BGC0001859: fosfomycin biosynthetic gene cluster from Pseudomonas syringae
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Location: 1 - 23,175 nt. (total: 23,175 nt).
This entry is originally from NCBI GenBank JX102649.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001859
Short description fosfomycin biosynthetic gene cluster from Pseudomonas syringae
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (phosphonate)
Loci
JX102649.1
via Enzymatic assays
Compounds
  • fosfomycin
Species Pseudomonas syringae [taxonomy]
References
Chemical products information
fosfomycin Evidence: NMR, Mass spectrometry
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C3H7O4P1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFM38982.1
 6610 - 7518 (-) F1 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
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    • AFM38983.1
    		 8404 - 9615 (-) MFS family transporter
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      • AFM38984.1
      		 9608 - 10627 (-) hypothetical protein
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        • AFM38985.1
        		 10614 - 11354 (-) hypothetical protein
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          • AFM38986.1
          		 11790 - 12665 (+) phosphoenolpyruvate phosphomutase
          • Scaffold biosynthesis
          • Activity assay
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          • AFM38987.1
          		 12628 - 13221 (+) hypothetical protein
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            • AFM38988.1
            		 13179 - 13955 (+) hypothetical protein
            • Scaffold biosynthesis
            • Activity assay
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            • AFM38989.1
            		 13972 - 14544 (+) epoxidase
            • Scaffold biosynthesis
            • Activity assay
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            • AFM38990.1
            		 14572 - 15357 (+) phosphotransferase
            • Resistance/immunity
            • Activity assay
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            • AFM38991.1
            		 15363 - 15992 (+) hypothetical protein
            • Resistance/immunity
            • Activity assay
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            • AFM38992.1
            		 15989 - 16876 (+) 6-phosphogluconate dehydrogenase
            • Scaffold biosynthesis
            • Activity assay
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            • AFM38993.1
            		 16861 - 18003 (+) trans-homoaconitate synthase
            • Scaffold biosynthesis
            • Activity assay
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            • AFM38994.1
            		 18014 - 18589 (+) non-heme Fe-binding protein
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              • AFM38995.1
              		 18779 - 19144 (+) hypothetical protein
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                Biosynthesis information
                Annotation changelog

                Entry version: 3

                Date
                Changes
                Submitters
                Reviewers
                2022-10-07
                Update chemical activity to schema version 2.11
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 2

                Date
                Changes
                Submitters
                Reviewers
                2022-09-15
                Fetch compound properties from PubChem
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                2022-09-15
                Removed gene names of 'No gene ID'
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 1

                Date
                Changes
                Submitters
                Reviewers
                2019-10-16
                Submitted
                • (ID: ZMZXFLPDGFEHMQPX76IB4OQ3)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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