BGC0001860: thiomuracin biosynthetic gene cluster from Thermobispora bispora DSM 43833
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Location: 604,806 - 621,192 nt. (total: 16,387 nt).
This entry is originally from NCBI GenBank CP001874.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001860
Short description thiomuracin biosynthetic gene cluster from Thermobispora bispora DSM 43833
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
CP001874.1
604806 - 621192
via Enzymatic assays
Compounds
  • thiomuracin
Species Thermobispora bispora DSM 43833 [taxonomy]
References
Chemical products information
thiomuracin Evidence: NMR, Mass spectrometry
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C62H55N15O13S6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • Tbis_0545
  • ADG87272.1
 604806 - 606020 (-) Coproporphyrinogen dehydrogenase
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    • Tbis_0546
    • ADG87273.1
    		 606239 - 607411 (-) cytochrome P450
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      • Tbis_0547
      • ADG87274.1
      		 607412 - 608632 (-) cytochrome P450
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        • Tbis_0548
        • ADG87275.1
        		 608653 - 609342 (-) transcriptional regulator, TetR family
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          • Tbis_0549
          • ADG87276.1
          		 609854 - 610003 (+) hypothetical protein
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            • Tbis_0550
            • ADG87277.1
            		 610088 - 612664 (+) Lantibiotic dehydratase domain protein
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              • Tbis_0551
              • ADG87278.1
              		 612661 - 613557 (+) hypothetical protein
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                • Tbis_0552
                • ADG87279.1
                		 613557 - 614633 (+) hypothetical protein
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                  • Tbis_0553
                  • ADG87280.1
                  		 614630 - 616006 (+) conserved hypothetical protein
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                    • Tbis_0554
                    • ADG87281.1
                    		 616003 - 617886 (+) protein of unknown function DUF181
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                      • Tbis_0555
                      • ADG87282.1
                      		 617879 - 619852 (+) protein of unknown function DUF181
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                        • Tbis_0556
                        • ADG87283.1
                        		 619864 - 621192 (+) amidohydrolase
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                          Biosynthesis information
                          Annotation changelog

                          Entry version: 3

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-10-07
                          Update chemical activity to schema version 2.11
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 2

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-09-15
                          Removed extra genes with no information
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 1

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2019-10-16
                          Submitted
                          • (ID: V2OY43CO37GLH274YHEO5ABU)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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