LOCUS       BGC0001863             11914 bp    DNA     linear   CON 11-FEB-2023
DEFINITION  Bacillus mycoides strain CER074 supercont1.4, whole genome shotgun
            sequence.
ACCESSION   BGC0001863
VERSION     BGC0001863
KEYWORDS    .
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            JH791994.1.
            The organism was changed from 'Bacillus cereus CER074' to 'Bacillus
            mycoides' in June 2018.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:27:17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11914
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..11914
                     /db_xref="taxon:1405"
                     /mol_type="genomic DNA"
                     /organism="Bacillus mycoides"
                     /strain="CER074"
                     /submitter_seqid="supercont1.4"
     protocluster    1..11914
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7619:7808]"
                     /cutoff="20000"
                     /detection_rule="(glycocin or sublancin)"
                     /neighbourhood="10000"
                     /product="glycocin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7620..7808
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(glycocin or sublancin)"
                     /neighbourhood="10000"
                     /product="glycocin"
                     /protocluster_number="1"
     cand_cluster    1..11914
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(glycocin or sublancin)"
                     /kind="single"
                     /product="glycocin"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..11914
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001863"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..11914
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="glycocin"
                     /region_number="1"
                     /rules="(glycocin or sublancin)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(700..1254)
                     /locus_tag="IEY_RS27940"
                     /old_locus_tag="IEY_05615"
     CDS             complement(700..1254)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101411.1"
                     /locus_tag="IEY_RS27940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05615"
                     /product="DUF3967 domain-containing protein"
                     /protein_id="WP_002130756.1"
                     /transl_table=11
                     /translation="MTPIIYENVSQIAKRLKISPSTVKKYYLLIESYNCYAFKRDERER
                     IIFNDYDVRLLQRLVELKSMPQVTLEDACKLLLKEEGLTVNNKNMTVITPGSDDLKEVL
                     RELKDTVELQQKQLQNQNEQIAKLTNVLESQQKLLTHSNTIEKQQVTDRDKAVMTVMRE
                     LQEVKQMVAASNEKKWYQFWK"
     gene            complement(2440..3024)
                     /locus_tag="IEY_RS27945"
                     /old_locus_tag="IEY_05616"
     CDS             complement(2440..3024)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033344.1"
                     /locus_tag="IEY_RS27945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05616"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_002130755.1"
                     /transl_table=11
                     /translation="MSKLVNLEQAEKKARLRDIENSKILSEEEMYIANELQAKASSRGM
                     KLVPERKIKNKAKFVQIIQQNIQYLFEIDYLTNAEKVFLLDISMCVGFLSNCLVSDINS
                     KEQIPLTQRELAKKIGRHETKVSPLVRKLIDKGIIARSESGVDDNNVRAYALFINPHIM
                     FSGNRDEVNPTLKAMFRKVPKQLKNLPIKLF"
     gene            complement(3291..3704)
                     /locus_tag="IEY_RS27950"
                     /old_locus_tag="IEY_05617"
     CDS             complement(3291..3704)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014639.2"
                     /locus_tag="IEY_RS27950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05617"
                     /product="disulfide bond formation protein B"
                     /protein_id="WP_002130754.1"
                     /transl_table=11
                     /translation="MKKISITRNQFLYFTFCISLFSILGSLYFSEVVGLNPCDLCWYQR
                     IFMYPLPLIIIISMLINDYKVKSYIRGFSLIGLLIGIYQYIIQLSHTKSAFCSIKSDCS
                     TIQVEWFGFITLPLLSVFAFFMIFISSFLVRKN"
     gene            complement(3721..4992)
                     /locus_tag="IEY_RS27955"
                     /old_locus_tag="IEY_05618"
     CDS             complement(3721..4992)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002130752.1"
                     /locus_tag="IEY_RS27955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05618"
                     /product="SunS family peptide S-glycosyltransferase"
                     /protein_id="WP_002130752.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-18,
                     bitscore: 56.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLYDFYQFVKMNNPNSQLFRDLCLIHNINTCDSIYLNLKDEIDN
                     SIQLYENSDFPLITCGIISYNEERCIQRCIDSVINEFDEIIVLDSVSVDQTTNIIKEKF
                     PEVKIFSELWKNDFSYQRNKLISYACNDWIYFIDADNYYGENNIGKAKRVARLIDFLEI
                     KCVISPMIHEYTGHIYVDTRRLFSLKHNILFSGKVHEEPVFDDKRIPDNIVVTIDVYHD
                     GYNPVIVNQLQKNKRNLELTEQMIQLEPNNPKWLFFYARELNQVKADKKLVKNVLLKAI
                     DLYEFSSEKRFLIESILLLCKISFEMKDFKTLIKYVSLMEKEFPNCYDIEFYKASLLLF
                     DLESRMNTIIESLHIAVDATNEHKYSEINSNGDHFKHLLINLYSLKQDWDSVFKLYNEV
                     QTPELKQDFLNNITKLKLKIDEIL"
     gene            complement(5031..5432)
                     /locus_tag="IEY_RS27960"
                     /old_locus_tag="IEY_05619"
     CDS             complement(5031..5432)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002130750.1"
                     /locus_tag="IEY_RS27960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05619"
                     /product="thioredoxin family protein"
                     /protein_id="WP_002130750.1"
                     /transl_table=11
                     /translation="MKKWFFITSLLVLSICAGFYIFNSKALEKPLYTNIDLKEYENHVN
                     SNDDVYIYVYKTSCPSCQQLKPVINKLIKEENLKLKALNIEEEKNYNESFLDKYKLNKT
                     PTILHYKEGKEIKRLEGYRPEELNEFFKK"
     gene            complement(5429..7531)
                     /locus_tag="IEY_RS27965"
                     /old_locus_tag="IEY_05620"
     CDS             complement(5429..7531)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 211.1; E-value:
                     4.8e-64)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002130748.1"
                     /locus_tag="IEY_RS27965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05620"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_002130748.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.1e-31, bitscore:
                     99.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKNKFIHTRQYNESDCGLACVSSLLKYYGFNYGIDYLRDLMMDK
                     KGYSLKDLILLLKNFKGLTCKPLEVNKDRLKEALNHINKPYIALIEEDGEKHYIVVYLK
                     KGDKLVISDPLKDKVSTMLVDDFSKVFSGVLLVVDSTDHNKLYNFDQRYKKTSFFKEVL
                     KENKLFFILTFILSVFVVGMAIVLSFFVKFLTDLVIPMRLDTTLIQFSLVFLTINFVKV
                     LFDYIRNYFVVRISYNLDKGLAEKYFNKIINMPIKFFENRDDGEIISRFRDSYHIRNAF
                     SVNVVTGILDVMIILGISFFLYKMNAVLFFTLLVPLLLLVSCAVIFYEILNKRNRELMA
                     NEAKTTSFLVPFIKNMPTIYSLNKEKYFFNSFQNFFRIQINSALKEFNVVNINNTVRML
                     IQSSFSIIILWVGTQQVLNDSITLGTLLLINSLAMFMLSSLERLISLQSELQKAIVATE
                     RFLDIVDYPVFQMKNTKEISNVFDIEFKDFSFSYDNLNSVVRDVNMKISKGDRVLLVGE
                     SGVGKSTLVKNLVKFYDVERSQILVNGIDINEVNTSTLREKIIYLNENPFLFKGTIKEN
                     LCMGKKFSDEELIRSCEIAGILDVVFSSNDNFDFKLNENATNLSTGQKQRFSLARAILH
                     NPEVLILDESLSNVDKESFERIHNNLLEMKFTLIVISHTSEALKNYNRKFIFKDKTIIE
                     EKEVLI"
     gene            complement(7620..7808)
                     /locus_tag="IEY_RS27970"
                     /old_locus_tag="IEY_05621"
     CDS             complement(7620..7808)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     glycocin: sublancin"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002130747.1"
                     /locus_tag="IEY_RS27970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05621"
                     /product="hypothetical protein"
                     /protein_id="WP_002130747.1"
                     /sec_met_domain="sublancin (E-value: 1.4e-19, bitscore:
                     59.8, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLFKELKVEELEEHVGNGGMGWAQCAALLAQCSSAGSFGCGGG
                     WSQAYSQCNTYRRSCNK"
     gene            complement(7971..8345)
                     /locus_tag="IEY_RS27975"
                     /old_locus_tag="IEY_05622"
     CDS             complement(7971..8345)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002130745.1"
                     /locus_tag="IEY_RS27975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05622"
                     /product="PH domain-containing protein"
                     /protein_id="WP_002130745.1"
                     /transl_table=11
                     /translation="MIKQDVLYENEVVENYIQAYYKNQTGLSILAGNVFNSPNIPGTLV
                     ATNLRMFFYTEVMKVNKILIEIDYKEIIEINEKKQSIGMFKTIPSIVVHHKEEEYFSTM
                     GDLEAFSKLKSFFSVIPVNK"
     gene            8878..9450
                     /locus_tag="IEY_RS27980"
                     /old_locus_tag="IEY_05623"
     CDS             8878..9450
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 107.8; E-value: 1.5e-32)"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017674723.1"
                     /locus_tag="IEY_RS27980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05623"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_002130744.1"
                     /transl_table=11
                     /translation="MNKKPHLIDVQPIRSKEQIEDMKWALKRHCSARDYILFLIGIHTG
                     LRVSDLLQLETQTIIKLKRKKRKEFKIKEGKTKKERMINLTSIFDEVYSYAQPLENTWL
                     FPSRKGDQPISKIQAYRQLQKAGDFAGIESIGTHTMRKTFGYWFYKQTKDVAMLQEILN
                     HSTPQITLKYIGINKEEKDNILDTFFL"
     gene            complement(9526..10338)
                     /locus_tag="IEY_RS27985"
                     /old_locus_tag="IEY_05624"
     CDS             complement(9526..10338)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002131483.1"
                     /locus_tag="IEY_RS27985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05624"
                     /product="hypothetical protein"
                     /protein_id="WP_002131483.1"
                     /transl_table=11
                     /translation="MFEEQLLDFYLKKLNIWNLVYKDVRKQLFSVISIFVLVFIGFLVF
                     IYLNNSFRQYIFFDPFYASLLYFLVYITLFICCMYLFVFRLAISTCITKYNISFKSKHW
                     KVFIYLMIQTYLYDRKILGSDSKLNEKSLDFLLNALKERKEEVNELNLLNTLSSYFALF
                     FLLAVPVWSAFNGWIYNHGGIDDLGKAIWYLATMILIIAISVFSIWMPIKVSLLEELFR
                     RKSSKILYLIKALESIKFSLENPNYVKTEKPGVIKQSIINSIVKEDNK"
     gene            complement(10380..10877)
                     /locus_tag="IEY_RS27990"
                     /old_locus_tag="IEY_05625"
     CDS             complement(10380..10877)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002130758.1"
                     /locus_tag="IEY_RS27990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05625"
                     /product="hypothetical protein"
                     /protein_id="WP_002130758.1"
                     /transl_table=11
                     /translation="MNTDKLINKILLSSDKELVSFIDRNFLCKNFDDFSDVKKKEESLF
                     KLNEDVLNHALFRLESLEEIYDTSKGSSAGFNLIGILFGFILKDYISIFVEPSIYPKLY
                     IFGQLMIFILISYGLIRILRNLNSSSENKSKIIYFKKLLDYVLKEKEKQKKKEVETKVH
                     AI"
     gene            11218..11883
                     /locus_tag="IEY_RS27995"
                     /old_locus_tag="IEY_05626"
     CDS             11218..11883
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.9; E-value: 3.3e-18)"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002091625.1"
                     /locus_tag="IEY_RS27995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IEY_05626"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_002130757.1"
                     /transl_table=11
                     /translation="MNIGKKIKHLRLINNMTQEDVASQLFISRQVISKWELGKSLPDLT
                     NLLALSNLFNVSIDSLLKEDSNLQNQIIKQSNYKRYLLIASLYIYSLITIVVIFYCLIA
                     FLLIPKDIKTSDLKVINSHFYQKSDKREILYIYSKLTPFFSNYSGDYSIETKDHEINIH
                     ANRNSIPFRNKDVLFSIEKDIPHGIDWEEKDIYIVDENNNKILIYNHKNKKLYYQIKN"
ORIGIN
        1 caataacaaa atacttatat ataaccataa aaataaaaaa ctatattatc aaataaaaaa
       61 ttaaagtagg tgatcaaaat tagaaacatc tataaatata cttttataat aactacattt
      121 atccttaacg taattagtac actacttatt gcaaatacag gatttgcacc aaacgttata
      181 gtattttcta ttagcttttt atttttcacc attttatttc aatcaatcac aattctattc
      241 attatctata tgattaaaaa tgatgcatct aaaaaaataa aaataatttt atacgttttt
      301 ttaacactag atatatttat ctttttatca ttgctataca tggcctatat cgtaataact
      361 caaactctat aaaaaaataa catactaata gcaaggaaat gcttgtatgc tgatctgtac
      421 tgcattccct tattctatgt atgctatatt cttattcgcc tttttctaac agtagaacca
      481 cgaatcttgg cgaagacatt ggtttttgcc ctgtcctggg gtccgtcctc gctttttatt
      541 ccacggttcc cttgaccacg agcctccgaa ccctcaaact cccaaagcta accccagcgg
      601 gcaaaaaccg cccttctggg gccacccctg gcgagtttgc atgagggttc ccctcatcgt
      661 caaggaactt tcgcggcata aacgccagga ctcagcaaat cacttccaaa attgatacca
      721 tttcttttca ttacttgctg caaccatctg ttttacttct tgaagttctc gcataacagt
      781 cataaccgct ttatcccgat cagtaacctg ttgtttttct atagtattag aatgagtcaa
      841 taacttttgt tgagattcca atacgtttgt tagtttagct atttgctcat tttgattctg
      901 taattgtttt tgttgtaact ctactgtatc ttttaattct ctcaatactt cttttaaatc
      961 atcagatcca ggagttataa cagtcatatt tttattatta actgttaatc cttcttcttt
     1021 taaaagtaat ttgcaagcat cttccaatgt aacttgtggc atacttttta actctactaa
     1081 tctttgtaat aacctaacat cataatcatt aaaaataatt cgttctcgtt cgtccctttt
     1141 aaaggcataa cagttataac tctcaattag taagtaatat tttttaaccg tagaaggtga
     1201 tatttttaat ctttttgcaa tctgggatac attttcataa ataataggtg tcataatagt
     1261 cataacctcc ttttcaatat ttcaaattcg ttataacagt tataactcct ttatcttaac
     1321 acttcacatg aaattaagtt atatcaatcc taattcttca tgcacagtat tcattagatc
     1381 ttgtacttac gaaataggta gttttaattt ctttttcttc tttggtactc actttactta
     1441 aattattcaa taaaaaacat acaaattaat taacactttg ttttttaaca taataatttc
     1501 cgactaaaaa tgaactactc tataaaattg gaaattctga atcaaaaaaa agagaagagc
     1561 ataaggggtt tttgggccca actaggggtt gggactaggc ggagcctagc ttaaacgtgg
     1621 gtacacgaaa attcccagga tgtccactca ctgacgacac aaaaccctcc aaatgtcccc
     1681 attatgtccc tagatgtaga ctcagtgagt acacaaagtc cctttgatgt ctccatatga
     1741 gtactcacta aggacatgat atttttaata aattgcaatc aaacattact ttaaaatact
     1801 aaaagaaaac aattggcatt aaataaatat aaatcctcag tctagaatca aataacaaga
     1861 aaatacaaaa tgctatttaa atgcttcaga atccttttta aaagatataa atctaaaaca
     1921 atactattta tcgttaaaac gaaaataaac gcttaaaaag caaaacaaac aggtttaaaa
     1981 gaaggtttac ctttgctttt ggggttgagg ctggttcgtc gtgtggggac gagcccccac
     2041 gtattacgta tctattaata tggtaagtga aattattaaa cgaaagcact agcggttcgg
     2101 ctcgtataat agcaattcaa gccgatgatc cccaatagtt gcttttggat gtatcggctt
     2161 ggtgatatcc aaactcgagc cgaaaaaagt tttgcaagga tgtagcaaag cgaaaagggt
     2221 ggagattttc tgaagcaaag cgaaagaaaa tacaacccgt tccttgcgga acttttagct
     2281 atttctatat agagtgagaa gggacaagca tactaaagtc gaaaataccc agtaatacca
     2341 aggctttcag gatttttcgt acttaccgtt tttggtaagt aaacttaccg tttttggtaa
     2401 gtacgaattt aataaaaaaa gtctacttta aaagtagact tagaataatt taataggtaa
     2461 atttttaagt tgtttgggaa cctttctaaa catagcttta agtgtcggat taacttcatc
     2521 tctatttcct gaaaacatga tgtgaggatt tataaataat gcatatgctc taacattatt
     2581 atcatcaaca ccactttctg aacgagctat aataccttta tcaattaact ttctaactaa
     2641 tggactaact ttagtttcat gtcttccaat ttttttagcc aattctcgct gagttaatgg
     2701 gatttgttct ttcgaattaa tatcactaac taaacaatta ctcaaaaaac ctacacacat
     2761 tgaaatatct aataaaaata ctttttcagc atttgttaaa taatcaattt caaataaata
     2821 ttggatattt tgttgaatga tttgaacaaa ttttgctttg ttctttattt tacgttcagg
     2881 aactaatttc attcctcttg aactagcttt tgcttgaagt tcatttgcta tatacatctc
     2941 ttcttctgac aagatcttcg aattctctat atctcttaat cttgcttttt tttcagcttg
     3001 ttctaaatta acgagctttg acataatctt tctcctcttt tctaacattt acaactagag
     3061 aagagcaaca ttttatgtta taatttataa agaaatttaa aaataaattt gtacacaaaa
     3121 gtcccttttc tctaattgat ggtttggtca ctttcaatta taacatatag ggactttttc
     3181 tatatctaaa attcaactat ataaaatatg cctatacact ttgtcccata taattattta
     3241 aaattcataa tattacctta ctaacatcct taaagaaatt cttataatat ctaattctta
     3301 cgtactaaaa atgaagatat aaatatcata aaaaatgcaa aaacacttaa aaggggtaaa
     3361 gtaataaatc caaaccattc gacctgaatc gtagaacagt cacttttaat actacaaaaa
     3421 gcactttttg tatgagaaag ttggatgata tattgatata tacctattaa caaaccaatt
     3481 aatgaaaatc ctcgaatata actcttcacc ttataatcat taattagcat agaaatgatt
     3541 ataattaaag gtaaaggata catgaaaatc ctttgatacc aacataaatc acagggattc
     3601 aaaccaacta cctcactgaa atataaactt cctaaaattg aaaaaagaga aatacaaaat
     3661 gtaaaataaa gaaattgatt tcgtgttata gatatttttt tcatactaat cccagctctc
     3721 ctataaaatt tcatcaattt tcaattttaa tttcgtaata ttatttaaaa aatcttgttt
     3781 taattccggt gtttggactt cattatacaa tttaaaaaca ctgtcccaat cttgttttaa
     3841 actatataaa ttaattaata aatgtttaaa atgatcccca ttagaattaa tttcactata
     3901 cttatgttca ttggttgcat ctacagctat atgtaaagat tcaataattg tattcattct
     3961 actttctaaa tcaaaaagta acaaagaagc tttataaaac tcaatatcat aacaattagg
     4021 gaattctttt tccatcaaag acacatattt tatcaaagtt ttaaaatctt tcatttcaaa
     4081 agaaatttta caaagcaaca aaatagattc aattaaaaat cttttttcag agctaaattc
     4141 atataaatct attgctttta ataatacatt tttaactaac tttttatcgg ctttcacttg
     4201 atttaattcc ctagcataaa aaaataacca tttaggatta ttaggttcta actgaatcat
     4261 ttgttcagtt aattcaagat ttcgtttatt cttttgaagt tgattaacaa taacaggatt
     4321 atatccatca tgatatacat ctatagttac aacaatatta tctggaattc ttttatcatc
     4381 aaaaactggt tcttcatgta ctttcccaga aaaaagtata ttatgcttta aagagaatag
     4441 ccttctcgta tctacatata tatgacctgt atattcatgg atcattgggc taataacaca
     4501 ttttatctct aaaaaatcta ttaaccttgc cactctttta gctttaccaa tattattttc
     4561 accataataa ttatcagcgt ctataaaata aatccaatca ttacatgcat aactaattaa
     4621 cttatttcgt tgataagaaa aatcattttt ccataattcg gaaaaaattt taacttctgg
     4681 gaatttttct tttattatat ttgttgtttg atcaacagag actgaatcta aaactataat
     4741 ttcatcaaac tcattaatta cactatctat acacctttgt atacatcttt cttcattata
     4801 actaataatt ccgcaagtaa ttaaagggaa gtcactattc tcatacaatt gaatactatt
     4861 atctatctca tcttttaaat ttagataaat ggaatcacat gtatttatat tatgtattaa
     4921 acacaaatcc ctaaaaagtt gtgaattagg attgttcatc tttacaaatt gataaaaatc
     4981 atacaaattc ataaaattac gcctcttcca tttgaaattt taaataatca ttatttttta
     5041 aagaactcat ttaactcttc tggacggtat ccttctaagc gcttaatctc ttttccttcc
     5101 ttataatgaa gaatggtagg agttttattc aatttatatt tatccaaaaa agactcattg
     5161 taattttttt cttcttctat atttaaagcc tttaatttta aattctcttc tttaatcaat
     5221 ttattaataa caggtttaag ctgttgacaa gaaggacaac tggtcttata tacatatata
     5281 taaacatcat cattagaatt gacatgattc tcatattctt taagatcaat atttgtataa
     5341 agcggctttt caagtgcttt agaattaaaa atataaaatc ctgcacatat agatagtact
     5401 aataatgaag taataaaaaa ccactttttc atattaaaac ctctttctct tcaattattg
     5461 tcttatcttt aaaaataaat ttacggttat aattttttaa tgcttcagaa gtgtgagaaa
     5521 taacaattaa tgtaaatttc atttccaaca aattattatg tattctctca aaactttctt
     5581 tatcaacatt actcaatgac tcatctagaa taagaacttc tggattatgc aaaatagccc
     5641 ttgctaaaga aaatctttgt ttttgtcctg ttgatagatt agtagcattt tcatttaact
     5701 taaaatcaaa attatcatta gaagaaaata caacatccaa aattcctgca atttcacaag
     5761 atcgaataag ttcttcatca ctaaattttt ttcccatgca caaattctct ttaatagttc
     5821 ctttaaaaag aaatggattc tcatttaaat aaataatttt ctctcttaat gtacttgtat
     5881 ttacttcatt aatatcgatt ccatttacta aaatttgaga tctttctaca tcataaaact
     5941 taactaaatt tttaactaaa gtacttttac caacaccact ttctcctact aacagaaccc
     6001 gatcgccttt agaaatcttc atattaacat ctctgacaac actatttaaa ttatcataac
     6061 taaaactaaa atctttaaat tcaatatcaa aaacatttga tatctcctta gtatttttca
     6121 tttgaaaaac tggataatct actatatcta agaatctttc agtcgccact atggcttttt
     6181 gtaattctga ttgtaaactt atcagccttt ctaaagaaga taacatgaac atagctaaag
     6241 aattaattaa taataatgtt cctaatgtaa tagaatcatt cagtacttgc tgagtaccaa
     6301 cccacaaaat aataatagaa aaagaagact gaattaacat tcgaacagta ttgttaatat
     6361 taacaacatt aaattccttc aatgccgaat ttatttgtat cctaaaaaaa ttttgaaatg
     6421 aattaaaaaa gtatttttct ttattcaacg aatatatagt aggcatattc ttaataaatg
     6481 gaactaaaaa agaagtagtc tttgcttcat tagccattaa ttctcgattt cttttattta
     6541 atatctcata aaagattact gcacaagaaa ctaaaagtaa caaaggtact aaaagagtaa
     6601 aaaatagcac agcattcatt ttataaagga aaaaacttat tcctaaaatt atcattacat
     6661 caagtattcc cgtaactaca tttacactaa aagcatttct aatatgataa ctatctcgaa
     6721 aacgtgaaat aatttcacca tcatctcgat tttcaaaaaa cttaataggc atattaatta
     6781 ttttattaaa atatttttca gccaatcctt tatctagatt atatgaaatt cgaacaacaa
     6841 aataatttct aatataatca aataaaacct ttacgaaatt tatagttaaa aatactaaac
     6901 taaattgaat taatgtagta tctaatcgca ttggaataac aagatctgtt aaaaatttaa
     6961 caaagaaaga aagaacaata gccataccaa caacaaatac agataaaata aaagttaaaa
     7021 taaaaaacaa tttattctct ttcaatactt ctttaaagaa agaagttttt ttataacgct
     7081 gatcaaaatt ataaagttta ttatgatctg tagaatctac aaccaaaagt accccagaaa
     7141 atacttttga aaaatcatca actaacattg tagaaacctt atcttttaat ggatcactaa
     7201 ttactaactt atcgcctttt tttaaataaa caacaatgta atgtttttct ccatcttctt
     7261 ctattaaagc tatataaggt ttatttatat gatttaaagc ctcttttaat ctatctttat
     7321 taacctctaa aggtttacaa gttaaacctt taaaattctt caacaaaaga attaaatctt
     7381 tcaaactata ccctttttta tccatcatta aatctcttaa ataatcaatt ccataattaa
     7441 aaccataata ctttaataaa gaggaaacac aagctaaacc gcaatcgctt tcgttgtatt
     7501 gtctagtatg tataaattta tttttcacca taaaatactc ttccttttat aatcaattat
     7561 tattctaacc aaaaagaaat ttcattaaat aatgaaattt ctctttggtt aaatttgatt
     7621 tatttattac aacttcttct atatgtatta cattgactat aggcttggct ccaaccgccg
     7681 ccacaaccaa agcttccagc acttgaacat tgagctaata atgccgcaca ttgtgcccat
     7741 cccattccac cattgcctac atgttcttct aattcttcaa cttttaattc tttgaataga
     7801 tctttcataa ttagtacctc catatttttt tactttaata ttaggaaatg taagcttact
     7861 attaaactct acaactttgt gcaaacgctt gcaatagttt tttcaaaaaa aatacaaaaa
     7921 aagatttttt atgtattttt tgtcatattt tttcatatat aaatttatac ttatttattg
     7981 actggaatta cactaaaaaa agattttaat ttagagaatg cttctaaatc tcccattgtt
     8041 gaaaaatatt cttcttcttt atgatgaaca acgatagaag gaatagtctt aaacatccca
     8101 atggattgtt tcttttcatt aatttctatt atttctttat aatcaatttc aataagaatc
     8161 ttatttactt tcattacttc tgtataaaaa aacattctca aatttgttgc tactaaagtt
     8221 ccaggtatat tagggctatt aaacacatta ccagctaata ttgaaagtcc agtttggttt
     8281 ttataataag cttgaatata gttttccacc acttcattct catacaacac atcttgtttt
     8341 atcataaata tctctcctta tttagaaata aaataactaa taataaatta ttatgatatt
     8401 tttaaaaaaa ctttatatta ctatattacc attaaatctc actataaaaa ttttaaaatt
     8461 ttgttattaa taaaattaat ttaaaaagat gttcaacatc aaaactctat ttataaaaaa
     8521 catctattta atatataata atatttgtat atcaaattga tatgaatatt attattgaat
     8581 ctatttccat acttaacaca aaacatacct tttactaact tataagagta gatgcaataa
     8641 gatttttcat tatatttata atgaatttgt taaatcttga aaataaaaat tataagacta
     8701 tataaaaaga aacctaattt attaggattc ttttttattc tccaaagtaa acttttagat
     8761 attagtttac attcaagttc ccttaatcat tgacttcaca ccaattcccc tgatatcctc
     8821 aatttatata ataaaagtat acattcaaaa cactataaat aaagaggtca taaaactatg
     8881 aacaaaaaac cacatcttat tgatgtccaa cccattcgta gcaaagaaca gatcgaagat
     8941 atgaaatggg ctcttaaacg tcattgttcc gcacgagatt atattctgtt tcttatcggt
     9001 attcataccg gattacgtgt aagtgatcta ctccaacttg aaacacaaac cataataaaa
     9061 ttaaaacgaa aaaagagaaa agaattcaaa atcaaagagg gaaaaacgaa aaaagaacgc
     9121 atgattaatc ttacttctat ttttgatgaa gtctattcgt atgcccaacc cctagaaaat
     9181 acctggttat tcccttcccg aaaaggagat cagcccatta gtaaaatcca ggcttatcga
     9241 caattgcaaa aagccggaga ttttgccggt atagaatcca ttggtactca taccatgcgc
     9301 aaaaccttcg gttattggtt ttataaacaa acaaaagatg tagccatgtt gcaagaaatt
     9361 ctaaatcata gcacaccaca aatcacatta aaatatatcg gtatcaataa agaagaaaaa
     9421 gacaacattc ttgatacatt ttttctttaa tatacttaac ttccgcatta ttcaacaact
     9481 taaattagcg aactttaaat gttcgctaat ttaaactaat atatactatt tattatcttc
     9541 tttaacaata gaattaatta tactttgttt tattacacca ggcttttctg ttttaacata
     9601 attaggattt tctaaagaaa acttaatact ttctaatgct tttatcaaat ataaaatctt
     9661 agaagacttc ctacgaaata actcttctaa taaggatact ttaataggca tccaaatcga
     9721 aaaaactgaa atagctatta tcaatatcat tgtagccaaa taccatattg cttttcctaa
     9781 atcatcaatt ccaccatgat tataaatcca gccattaaat gctgaccata ccggaacagc
     9841 taataaaaaa aacaaagcaa aataactaga taaggtattt aataaattca gttcattaac
     9901 ttcttccttt ctctctttta acgcatttaa taaaaaatcc aatgattttt cattaagttt
     9961 tgaatcgctc cccaaaatct ttctgtcata taaataggtt tgaatcatta aataaataaa
    10021 aactttccaa tgcttacttt taaaagaaat attatattta gtaatacaag tagaaatcgc
    10081 taaacgaaat acaaataaat acatacaaca tataaataac gttatataaa ctaaaaaata
    10141 aagtagtgaa gcataaaaag gatcaaaaaa aatatattgt ctaaaagaat tattcaaata
    10201 aataaacact aaaaacccaa taaaaactaa aacaaaaata gaaataacac taaataattg
    10261 ttttcgaaca tccttataaa ccaagttcca tatatttaac ttttttaaat aaaaatctaa
    10321 taattgctct tcaaacatat aaaatactcc ttaaattaaa atttgatcct attaaaaacc
    10381 tatatagcat gaacttttgt ttctacttct tttttctttt gtttttcctt ttctttcaat
    10441 acataatcta acaacttttt aaaatatata attttagatt tattttcact agacgaattt
    10501 aaatttctta atatccttat caggccatat gatatcaaaa taaaaatcat taattgacca
    10561 aaaatataca atttgggata aatactaggt tcaacaaata tagatatata atcttttaaa
    10621 ataaatccaa aaagtatacc tatcaaatta aaacctgctg acgaaccttt agaagtatca
    10681 taaatttcct ctaaactttc aagtctaaaa agagcatgat taagaacatc ttcatttaat
    10741 ttaaacaaag attcttcttt cttctttaca tctgaaaaat catcaaaatt tttacataaa
    10801 aaatttcgat ctataaaaga aactaattcc ttatcagaag agagtaaaat tttatttatt
    10861 aatttatcag tattcataat ataactccta ttcattaaat attacattac aaatttagct
    10921 ataaaaaata aaaaagactc taatttaaag agtccttttt atttaatata actaagcacc
    10981 tcttttagac gaattcatcg ctattacatt taaaatgtaa tatacaaatc cataaataaa
    11041 tataacataa aataataatt atatatacaa aaattgtaaa aacaaaagaa caaaaaataa
    11101 attgatagtc caaaatccag catgcaacac aacgttgcat gcctttttta taacgctacg
    11161 atgcgtttct tactatttaa cattagaata attaaagtaa ttaaaggagg tacatatatg
    11221 aacattggaa aaaaaataaa acatttaaga ttaataaata acatgacaca agaagatgta
    11281 gccagccaat tatttatttc aagacaagtt atatctaaat gggaactagg aaaaagcctt
    11341 cccgatctaa ctaatttatt agctttaagc aatctattta atgtttcaat tgattcttta
    11401 ttaaaggagg attcaaattt gcaaaatcag ataataaaac aaagcaatta taaaagatat
    11461 ttattaatag cctctctata catatattct ttaattacta ttgttgttat attttattgt
    11521 ctcattgcct ttttacttat accaaaggac ataaaaacat cagatctaaa ggttattaat
    11581 tcacactttt atcaaaaaag cgataaaaga gaaattcttt atatttatag taaattaaca
    11641 cctttcttct ccaattattc aggagattat agcattgaaa caaaagatca tgaaataaac
    11701 attcatgcta atcgaaattc aattcctttt agaaataaag atgttttatt ttcaattgaa
    11761 aaagatatcc cccatggaat agattgggaa gaaaaagata tttacattgt agacgaaaac
    11821 aataacaaaa tacttatata taaccataaa aataaaaaac tatattatca aataaaaaat
    11881 taaagtaggt gatcaaaatt agaaacatct ataa
//
