BGC0001866 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001866 (Paecilomyces variotii)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	33,290	viriditoxin	Polyketide	64%

BGC0001866 - Region 1 - T1PKS

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Location: 1 - 33,290 nt. (total: 33,290 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 33,291
Label		BGC0001866

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002030.1	0.67	Polyketide	viriditoxin	Byssochlamys spectabilis
BGC0001866.1	0.67	Polyketide	viriditoxin	Byssochlamys spectabilis
BGC0001858.1	0.28	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0000041.1	0.28	Polyketide	oronofacic acid	Pseudomonas syringae
BGC0001068.1	0.25	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001909.1	0.24	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000107.1	0.23	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001258.1	0.22	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001265.1	0.22	Polyketide	melanin	Bipolaris oryzae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002030.1	0.87	Polyketide	viriditoxin	Byssochlamys spectabilis
BGC0001866.1	0.87	Polyketide	viriditoxin	Byssochlamys spectabilis
BGC0001858.1	0.62	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0000041.1	0.61	Polyketide	oronofacic acid	Pseudomonas syringae
BGC0001068.1	0.58	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001909.1	0.57	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000107.1	0.56	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001258.1	0.55	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001265.1	0.55	Polyketide	melanin	Bipolaris oryzae

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 33290:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (Me-pk) + (mal)
Non-colinear ordering:: C8Q69DRAFT_515060 + C8Q69DRAFT_480069

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

C8Q69DRAFT_515060

PKS_AT (512..808): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Isobutyryl-CoA: 66.7%; Methylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 73.4
Methoxymalonyl-CoA: 65.4
Ethylmalonyl-CoA: 43.8
Isobutyryl-CoA: 29.6
trans-1,2-CPDA: 27.4
Benzoyl-CoA: 23.3
Propionyl-CoA: 22.7
Malonyl-CoA: 18.0
Acetyl-CoA: 11.5
fatty_acid: 10.1
2-Methylbutyryl-CoA: 4.8
CHC-CoA: 4.2
inactive: 0.0
3-Methylbutyryl-CoA: 0.0

C8Q69DRAFT_480069

PKS_AT (906..1205): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 58.3%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 120.6
Methoxymalonyl-CoA: 78.2
Methylmalonyl-CoA: 72.6
inactive: 53.4
Propionyl-CoA: 35.2
2-Methylbutyryl-CoA: 30.8
Isobutyryl-CoA: 26.6
Ethylmalonyl-CoA: 25.1
fatty_acid: 19.9
3-Methylbutyryl-CoA: 19.2
CHC-CoA: 16.6
Benzoyl-CoA: 13.0
trans-1,2-CPDA: 10.9
Acetyl-CoA: 9.6