LOCUS       BGC0001870             14658 bp    DNA     linear   BCT 23-OCT-2017
DEFINITION  Xenorhabdus budapestensis strain DSM 16342 Xbud_1, whole genome
            shotgun sequence.
ACCESSION   BGC0001870
VERSION     BGC0001870
KEYWORDS    .
SOURCE      Xenorhabdus budapestensis
  ORGANISM  Xenorhabdus budapestensis
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Xenorhabdus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 05:06:15
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 354426
            Orig. end    :: 369084
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..1812
                     /locus_tag="Xbud_00361"
     CDS             1..1812
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="Xbud_00361"
                     /product="desferrioxamine siderophore biosynthesis protein
                     dfoC"
                     /protein_id="PHM29812.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.8e-81, bitscore:
                     262.1, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSLYTKTELGSQSSHLTKENWSHANRHLVAKILRELSHEKLIYP
                     VHNQGKSYSIEIGKFQYHFQAQDCQLEHLDIDSSSIEKFIHGQPQQLDAIQLIIDLYPL
                     LGISEKMLPIYLDEISSTLYGCAFKYLNNRLTAQDLTQADYQTVETAMTEGHPVFIANN
                     GRIGFDSDDYLQYAPESANPVTLIWIAVHRNKTVFSALSSLSYSQLLAEELEKYLPAQF
                     ERYMQKLGLNLSDYYLMPVHPWQWKHRITISFAADIANQDIVYLGEGNDRYLAQQSIRT
                     FFNISQPKKNYVKTALSVLNMGFMRGLDPHSMVTTPQVNEWLYHLVAADTFFQQKGFTI
                     LRERAAMGYFNHYFESAIKKDNPHKKMLSALWRESPMTILEENQRLMTMASLLHVDREG
                     NAVIAALVQDSGLSVEMWVARYLDAYLSPLLRSFFTYDLVFMPHGENLMLVLENNIPVK
                     MLMKDIGEEIAILNGDLQLPEEIDFLHVTVQDDMKINYIFLDIFDCFFRYLSPLLQKHL
                     ALSETHFWELVAQCVYNYQSQHLNQIEKFCQFDLFKHDFVRTCLNRLQMANNQQMIDLD
                     DREKNLKFAGTLVNPLHAFREKYSVTV"
     subregion       1..14658
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="Other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..14658
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1895..4108
                     /locus_tag="Xbud_00362"
     CDS             1895..4108
                     /codon_start=1
                     /gene_functions="transport (smcogs)
                     SMCOG1051:TonB-dependent siderophore receptor (Score:
                     528.2; E-value: 5.6e-160)"
                     /gene_kind="transport"
                     /locus_tag="Xbud_00362"
                     /product="ferric alcaligin siderophore receptor"
                     /protein_id="PHM29813.1"
                     /transl_table=11
                     /translation="MINPILQRNQLTKRKVLSVLIPLLLAGNHSAIAEEAQGKNDKIIV
                     TAGTPEHEGVTEDSGMYNTTSMVTSTGLNLSARETPQSVSVMTKQRMVDENLDSVKSAI
                     GSITGMTVNQADSDRFTFSSRGMTVRNMLRDGVPTFYDIRFNYGDNLMDTVMFDRLEVV
                     RGAAGLMVGPGTPSAAVNVIRKRPTSDFRGEITLEGGSWDKWRTGLDLSSPLNEDGTVR
                     GRFVTAYQRSNSFIDRDKHEKYPFYGILEADLTDNTLLTIGADYQINHTRGGMFGGLPI
                     YFKDGSKTDYKRSNSYAPDWAFSKVRSSSIFTSLQHKFDNGWSAKGTFTYDNNALDQKV
                     LWATGFPDRITNQGMYPGSMTLIDGTRRQRNFDLQLNGNYGLLGRTHHASFGLNYQKQN
                     FRNDYYNAPCMKSRSCSNFPIGDFTQPSWGYPEPTWSKTRDTGSNGYIEQTAGYAVTQL
                     SLADPLTLILGGRITSWKTRGDNFGTPQNGTYNNEFVPYGGLVYNITPDFSVYGSYTKI
                     FEPEARINRHNQLLKPVTGENYELGLKGVAFNNGLDYSLAIFEIHQDNYTIRDNSKERH
                     SAIPKNSTVYYAANGIKTRGFEAEVSGQITDDWRLYAGYTQFRATMPGGKRVNTDKPNR
                     LFKLFTTYALPGVMNDLTLGGGVNWQDKTRLELDSPNGKREDGQGSFTTVNLMGRYQFT
                     PDLSLTVNLNNVFDKKYYTSFGSYTHYYYGAPRNVEATLRYKF"
     gene            4176..5234
                     /locus_tag="Xbud_00363"
     CDS             4176..5234
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 181.2; E-value:
                     3.7e-55)"
                     /gene_kind="transport"
                     /locus_tag="Xbud_00363"
                     /product="putative lipoprotein"
                     /protein_id="PHM29814.1"
                     /transl_table=11
                     /translation="MMLIQRVRTHCRILAAVPLILLIGLLVGCDKPTTANNIPVDTTDY
                     SKAGYPKIITTELGTAVINQPPQRIVALGTGTEDILLDLGVIPVGIESHRWGGDTDGYL
                     PWFREEIERRGAKLPAIIEMYPELDIEKIIKLKPDLVLATQSGITQQNYDHLSHFVPVI
                     AYPHKPWQTTPRQQIELVARALDKMPQGEKLNAELDAILTQTGSTIPNIKHYSFAYIKA
                     GTTGNTLSIYVKNDPRVDTLVHLGLSLLPLADSLTAPFGSFAFNIGLENADLLNGADIL
                     VTWYTSEKERQQTEAQPLFRSIRAVREGGYIPMTDQSLVMSMSYGSLLSLRWGLPRFMP
                     LLKLEIAKHEKH"
     gene            5221..6231
                     /locus_tag="Xbud_00364"
     CDS             5221..6231
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 277.3; E-value: 2.4e-84)"
                     /gene_kind="transport"
                     /locus_tag="Xbud_00364"
                     /product="hypothetical protein"
                     /protein_id="PHM29815.1"
                     /transl_table=11
                     /translation="MRNTKQRLSLTLGLVLMALLTCLCVAVSLSLGSKSLPLSAIWQHY
                     WLGDQGSYYDLVINAREPRTLIGLMAGAALALAGTVTQGLLRNPLGDPGLLGINAGAAT
                     AVVFFSFIPVLDQLPRFGTAFIGAGLSTLLFYLLSGGSRNTNPVRLVLTGAAINASLFA
                     VVQGIVLMNAQAMDSYRFWTMGSLSTMSLREASLLIPYLLVAIVLTLSLSASLNVMVFG
                     EGIAGSLGANVARTRILSLLSATMLAAGATAMAGPIAFIGLVAPHLMRALVGSDFRWLL
                     PYCLFAGPCLLLISDVVGRLLIAPEEIMVGIITAALGAPLLYLVAKNRTQKIMVE"
     gene            6236..7288
                     /locus_tag="Xbud_00365"
     CDS             6236..7288
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 229; E-value: 1.2e-69)"
                     /gene_kind="transport"
                     /locus_tag="Xbud_00365"
                     /product="putative ferrichrome ABC transporter permease"
                     /protein_id="PHM29816.1"
                     /transl_table=11
                     /translation="MTQIDSSTPIRQPRVRTFALGKAVFITPSWQTRKMVFSMLLLLVV
                     LFYLTLSLGREGMDNPFLTTETPYQEFILLQIRLPRALLAIGAGIALALSGTLFQLTTR
                     NALGSPDIIGINAGAAVGIMAALLIWPGVLPIPLGGLLGAGLAVLLVYFGNGAGLGRMQ
                     TGKIVISGVAVAAFCMAMVDFAVSNIRIEQAQQIRSLLIGSLASRGWQDVITISGLIIF
                     TPVLFWLGRQLNYTHFGDDIANTLGVPVRFIQIVSILLAVIFAAMSVLVVGPVSFIALS
                     APQIAHRLVHAKGAALFCSALVGALLMLLSDLITLILPTPARLPVGLVTAVIGGIYLMY
                     LLYAELRRTR"
     gene            7288..8103
                     /locus_tag="Xbud_00366"
     CDS             7288..8103
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 198.3; E-value:
                     2.5e-60)"
                     /gene_kind="transport"
                     /locus_tag="Xbud_00366"
                     /product="hypothetical protein"
                     /protein_id="PHM29817.1"
                     /transl_table=11
                     /translation="MPSDENSPVTTSRLKALDLSLAYGKRTIIDGINIAIHDSEFSVII
                     GPNGCGKSTLLRAISRSMQPQQGEVQLDGINIHRYKPKAVARELSLLTQGAVITEALTI
                     YDLVSRGRYAYQTFLRQWSEEDERVVNEALRAVDLWDMSQKLVSELSGGQRQRAWFAMT
                     LAQQTPIILLDEPTTYLDISHQIEMLDLCQRLHQQGKTLVLVLHDINLALRYATRLIMM
                     KNGQVYAEGKPEEIITEQSIADVFGLACCIIRDPESDKPLVIPRYNRRV"
     gene            8105..8872
                     /locus_tag="Xbud_00367"
     CDS             8105..8872
                     /codon_start=1
                     /locus_tag="Xbud_00367"
                     /product="putative iron transport-related membrane protein"
                     /protein_id="PHM29818.1"
                     /transl_table=11
                     /translation="MANKNNHSSNQMISKIDINDIVNLFDSAFSHFNSSMKVNAGNIPS
                     ESMDFYQWSNEKEFSLLMQRYQNEYYGNNEQKPNNKGLYSLWAQWYFGLVVPPIMLMLL
                     EYPQAVDADYHLFQVEFHESGRPNMVYYQLNWMKEPISLLERYYSLLDRHIIPVCEKIE
                     SYRGINGRLLWNNIGYVMYWYLSNFRERMDAEQYNILVNNLFFEQKLPDGRDNPLYRTV
                     ILRNNVIQRRCCCQRNKLPGVGNCHDCPLESTA"
     gene            9291..10907
                     /locus_tag="Xbud_00368"
     CDS             9291..10907
                     /NRPS_PKS="Domain: Beta_elim_lyase (169-367). E-value:
                     6.1e-07. Score: 20.8. Matches aSDomain:
                     nrpspksdomains_Xbud_00368_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 387.6;
                     E-value: 1.3e-117)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Xbud_00368"
                     /product="putative decarboxylase involved in
                     desferrioxamine biosynthesis"
                     /protein_id="PHM29819.1"
                     /transl_table=11
                     /translation="MFEESQVFAESLAKNTYLTGNDNFKNSDSFKENHFNQYLLNGDNA
                     GSYLEDSCDVIVKLKRILQKTKSPFSGILPNELSSSFKKINLDNPLGSWEHALEELQHL
                     YIKDAVYFHHPKYVAHLNCPLVLPSAIAETIIGCINSSVDTWDQSAGGTLIEQKVLDWT
                     LDKIGLGKEADGIFTSGGTQSNLMAMLLARDWFCHQRNPGHKNQLHGLPADFHKLRIFS
                     SSVSHFSTQKAAAILGLGYNAVVSVPCDDEFRMSVQALEANIKQCFDEGNIPFAIVATA
                     GTTDFGSIDPLPLLADLAEKYSLWLHVDAAYGCGLLVSSRHSHLLQGIDRADSVTVDYH
                     KSFFQPVSCSAFFVKNKQHFSHLTYHAEYLNPLSAEQEGTPNLVNKSIQTTRRFDALKM
                     WLTLRVIGAEQLGQAFDTLLDTAQSAYHLMRQNPCFELVHQPVLSTLVFRFVPKQGFPE
                     YAIDHLNANIRKALFREGECVIAGTKINDRQYLKFTFLNPATTVKHLQEIIDSIVTQGN
                     LLLTDLVFSDDSLFNQHQAVY"
     aSDomain        9798..10391
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Xbud_00368_Beta_elim_lyase.1"
                     /evalue="6.10E-07"
                     /label="Xbud_00368_Beta_elim_lyase.1"
                     /locus_tag="Xbud_00368"
                     /protein_end="367"
                     /protein_start="169"
                     /score="20.8"
                     /tool="antismash"
                     /translation="GKEADGIFTSGGTQSNLMAMLLARDWFCHQRNPGHKNQLHGLPAD
                     FHKLRIFSSSVSHFSTQKAAAILGLGYNAVVSVPCDDEFRMSVQALEANIKQCFDEGNI
                     PFAIVATAGTTDFGSIDPLPLLADLAEKYSLWLHVDAAYGCGLLVSSRHSHLLQGIDRA
                     DSVTVDYHKSFFQPVSCSAFFVKNKQHFSHLTYHA"
     gene            10934..12253
                     /locus_tag="Xbud_00369"
     CDS             10934..12253
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 397.5;
                     E-value: 1e-120)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Xbud_00369"
                     /product="L-lysine 6-monooxygenase involved in
                     desferrioxamine biosynthesis"
                     /protein_id="PHM29820.1"
                     /transl_table=11
                     /translation="MTTKTYDFIAIGVGPFNLGLACLVQPIKEITSLFIDQKAGFDWHP
                     GMMLENSTMQTPFMADLVTLASPTHPLSFLNYIKEKGRIYSFYIRENFFLMRKEYNQYC
                     QWAAEKLSNLRFNTKVEDISYDEAHSHYILQCADTLTGQKHQFFAKKLVLGTGPSSYIP
                     KCCKPFENQMITSGNYLSNKAALQQKKSITVLGSGQSAAEIFYDLLQDVDTYGYQLNWV
                     TRSPRFFPLEYTKLTLEMTSPEYVDYFYSLPENKREELNRSQKSLYKGINSSLINEIFD
                     LMYTKRLNGELNVSLYTNSELREIHCITENQNTVVKQKFVLDLFQQEQEALFYLETEGV
                     VLATGYQYQVPGFIEGIQQRIRWDKRGRYDVQRNYSIDYNNEIFVQNVELHTHGFVTPD
                     LGMACYRNSRLIEEITGKEHYVIEKSISFQQFSVASEGVC"
     gene            12253..14658
                     /locus_tag="Xbud_00370"
     CDS             12253..14658
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="Xbud_00370"
                     /product="desferrioxamine siderophore biosynthesis protein
                     dfoC"
                     /protein_id="PHM29821.1"
                     /sec_met_domain="IucA_IucC (E-value: 6.5e-79, bitscore:
                     254.3, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDIAPISFEKKLPDLGTFSLRPLDIDEDIAVITDWVNRDYACYW
                     GMQDHTEQQVRDFYQDLIENQPDSVFIGIYQEQPVFLLECYWAQKDQIGQYYDALPDDM
                     GMHILVAPSDKKIKQFTWGIFQTIIAFIFSNSAVNRIVVEPDIRNEKIHRLNLRAGFVY
                     HKTVQLPHKTAGLAFCTREQHQIALQSAELPETLNHSDAFVRHLYPAIWQKVNRLHLKK
                     AISEFAHECLLSPELLTETTDQDGYRHYHLENNEHSVDYHFRARRLALDHWLIDADSLR
                     KMQAGDWVELDFILFIIEFKKQIGISDTVMPTYLEELTSTLHSSAFKYHRSGIKVEELV
                     DADFQAIEAEMMEGHPIFVANNGRIGFDAEDFQNFSPESAADIRLIWLAAHKRKAHFAC
                     IEQLTYQQLLEQELGKEEVTQFNNKLILMGLNPEEYLLMPFHPWQWQNKLPSVFAHDLA
                     NRNLIYLGKGSDIYQAQQSIRTLFNRSNPQRFYVKAALSILNMGFMRGLSPYYMATTPG
                     INEWLFDLVENDVVLQRCGFRLLREVASIGFRSSYYEQAINGDTPYKKMMAALWRENPL
                     QLIENNQNVMSMAALLHHDQQGNAFLPALISASGLSTDEWVRRYLGCYLLPLLHCLYAY
                     DLMFMPHGENIIMVLEEHIPQYIFMKDLAEEILVMNPDADLPEKASRVKVNMPEEMKSL
                     TILSDVFDGVFRYLSAILDEQGGYPQDDFWKAVADCILDYQFEHPELKEKFIQYELFTP
                     EIKRCCLNRLQIANNRQMLDLSDPSKSLKFSEELINPIAVFVKTAHIK"
ORIGIN
        1 atgacttcgc tgtacaccaa aactgaatta ggttcccaat cctctcatct aaccaaggaa
       61 aattggtcac atgcaaatcg gcatctcgta gctaaaatac tgcgtgaatt gtctcatgaa
      121 aaactgattt atccagtaca caatcaggga aagtcttatt ccattgaaat tggtaaattt
      181 caataccatt ttcaggctca ggattgtcaa ctagagcatt tagatattga ttcttcatca
      241 atcgaaaaat tcatccacgg tcaaccacaa caattggatg caattcaact gatcattgac
      301 ttgtatccat tgctgggcat atcagaaaag atgctgccta tttatcttga tgagatatcc
      361 agcacacttt atggatgtgc ttttaaatat ctgaataata gattgacagc acaggattta
      421 acccaagcgg attatcagac tgtggaaacg gcaatgactg agggccatcc ggtttttatt
      481 gccaataatg gtcgtattgg ttttgactca gatgattact tgcaatatgc gccagaaagt
      541 gcaaatccgg tgacattaat ttggatcgct gtacatcgca ataaaactgt tttctcagca
      601 ttatcttcgc tttcttattc tcagctgttg gcggaggaat tggaaaaata tttgccagcc
      661 cagtttgaac gatatatgca aaaattggga ttaaatctgt cagattatta tctgatgcca
      721 gtacatccct ggcagtggaa gcatcgtatt accatcagtt ttgcggcaga tattgctaat
      781 caagatatcg tttatctcgg tgagggcaat gatcgctatc tggctcagca atctatccgc
      841 acgtttttca atattagcca gcctaagaaa aactatgtca aaacagccct atctgtcctt
      901 aatatgggat ttatgagagg tttggatccc catagtatgg taacaacacc acaagttaat
      961 gagtggcttt accatttggt agcagcagat actttctttc agcagaaagg atttaccata
     1021 ttacgtgaac gggcggcgat ggggtatttt aaccattatt tcgaatccgc tatcaaaaaa
     1081 gacaacccac ataaaaaaat gttgtcagca ctatggcgag aaagcccaat gacgatcttg
     1141 gaagagaacc aacgtctgat gacgatggcg tcgttgttac atgtcgatag agaaggcaat
     1201 gcagtcattg ctgctttggt acaagattct ggtttatctg tagaaatgtg ggtagcccgc
     1261 tatctggatg cttatctttc accattacta cgttctttct tcacttatga tttggtcttt
     1321 atgccacatg gtgaaaatct gatgttagtg ctggaaaaca atattccagt gaaaatgttg
     1381 atgaaagata ttggtgaaga aattgccatt ttgaatggag accttcaatt acctgaggag
     1441 attgattttc tacatgtcac tgttcaggat gatatgaaga ttaactatat attccttgat
     1501 atttttgatt gtttcttccg ttatttgagt ccgttattgc aaaaacatct tgcattgtca
     1561 gaaacacatt tttgggaatt agttgctcag tgtgtttata actatcaatc acagcacttg
     1621 aaccaaatag aaaaattctg ccaatttgat ctatttaagc atgattttgt acgtacttgc
     1681 ttaaatcgac tgcaaatggc gaataaccag caaatgattg atcttgatga tcgagaaaaa
     1741 aatctgaaat ttgctggaac gttagttaat ccccttcatg catttcggga aaaatattcc
     1801 gtcacggttt agaacaaatg ggttagaaca atagttgacg gaaatacata aagtaaacat
     1861 aacaataaat tatttagata acaggatgaa tagagtgata aacccaattt tgcaacgaaa
     1921 tcagttaacc aagagaaaag tcctttctgt tttaatccca ctgcttcttg cagggaatca
     1981 ttcggcaata gcagaagaag cacaaggaaa aaacgataaa attatcgtaa cagcaggaac
     2041 tccggagcat gaaggggtaa ccgaagatag tggcatgtat aacaccacct caatggtgac
     2101 atcaacgggt ttgaatttgt ctgcgcgtga aacgccacaa agtgtcagtg tgatgaccaa
     2161 acagcggatg gtggatgaaa atctggacag tgtaaaaagt gccataggca gtattacggg
     2221 gatgacagtt aatcaggctg acagtgatcg tttcactttc tcttcaaggg gaatgactgt
     2281 cagaaacatg ctgcgcgatg gtgtaccgac tttctacgat atccgtttta actatggtga
     2341 taacctgatg gacaccgtca tgtttgaccg cctggaagtc gtacgaggtg cagcgggttt
     2401 gatggttggg ccgggtacac cttctgccgc tgtgaatgtg atccgcaaac gtccaaccag
     2461 cgattttcgt ggtgaaatta cacttgaggg tggctcttgg gataaatggc gtactggtct
     2521 tgatctctct agtccattaa atgaagacgg tacagtcaga gggcgttttg tcaccgccta
     2581 ccagcgttcc aactctttta tcgatcgcga taaacatgaa aaatatccat tctatggcat
     2641 tcttgaagcc gatctgacag acaacacttt gctgaccatt ggtgctgatt atcagattaa
     2701 ccatacccgt ggcggaatgt ttggtggttt gccgatttat tttaaagatg gcagtaaaac
     2761 tgattataaa cgcagtaaca gctatgcacc ggattgggca ttttctaagg ttcgttcatc
     2821 ttctatcttt accagcctgc aacataaatt tgataatggc tggagtgcga aaggaacctt
     2881 tacttatgac aataatgccc ttgaccaaaa agtattatgg gcaacgggtt ttcctgatcg
     2941 tatcactaat cagggaatgt atccgggtag tatgaccctg atcgatggaa ctcgtcgtca
     3001 gcgtaatttt gatttgcagc taaatggtaa ttatgggttg ttggggcgta cacatcacgc
     3061 aagttttggt ttgaattatc agaaacagaa tttccggaat gattattaca atgccccatg
     3121 tatgaaatct cgtagttgtt caaatttccc aataggtgat tttacccagc cttcatgggg
     3181 ttatcctgag ccaacatgga gtaaaactcg tgacactggt tcgaatggtt atatcgaaca
     3241 aaccgcaggt tatgcagtta ctcagctttc attagcagat ccattaacat taatcctcgg
     3301 tggacgtatt acgagttgga aaacccgtgg tgataatttt ggtactccac agaatggcac
     3361 ctacaataat gagtttgtgc catatggtgg cttggtttac aacatcactc cagatttctc
     3421 tgtttatggt agttatacca aaatttttga accagaagcc cgtattaatc gccataacca
     3481 actcctcaag ccggttacag gggaaaacta cgaactgggt ctgaaaggtg ttgcatttaa
     3541 taacggcctt gattattcct tggcgatttt cgagatccat caggataatt atacaattcg
     3601 tgataattct aaagagcgac actcagccat tccaaagaat tctactgttt attatgcagc
     3661 caacggtata aaaacccgtg gttttgaagc tgaagtcagt ggccagatta ccgatgactg
     3721 gcgtttgtat gcgggttaca ctcaattccg cgccaccatg cctggtggta agcgtgtcaa
     3781 tacagataaa ccaaatcgtc tgttcaaatt gtttactact tatgccttac ctggagtaat
     3841 gaatgatctg actcttggtg gaggagttaa ctggcaggat aaaacacggc tggagcttga
     3901 tagccccaac ggtaaacgtg aagatgggca aggtagcttt accacggtta acctgatggg
     3961 acgttatcaa tttacgccag acctttccct gactgttaac ctgaataatg tgtttgacaa
     4021 aaaatactac acctcattcg gtagttacac tcattactac tatggtgcac cacgtaatgt
     4081 cgaagcgact ttacgttata agttctaact gaatcacggg cggcggtgat gtacttttat
     4141 ctatttaaac aacaagcggt aaaggatcat aagcgatgat gttgatacaa agagtacgaa
     4201 cacattgcag aattttggcc gccgtgccgt tgatattgtt gatcggttta ttagtcggtt
     4261 gtgataagcc gacaacagca aacaatatac cggtggatac caccgattat tcaaaagctg
     4321 gctatcctaa aatcattacc actgaactgg gaacggcggt gattaaccaa ccgccgcagc
     4381 ggattgtggc attgggaacc ggtactgaag atattttgtt agatcttggt gttattcccg
     4441 tgggtattga atcgcaccgt tggggtgggg atacagacgg gtatttaccc tggttcagag
     4501 aggaaataga gcgacgtggc gcaaaattac cagctattat cgaaatgtat cctgagctgg
     4561 atatcgaaaa aatcatcaag ctgaaaccgg atttagtttt ggcaacacaa tcaggtatta
     4621 cacagcaaaa ttatgatcat ctgtctcatt ttgtccctgt aattgcctac cctcataagc
     4681 cgtggcagac gacaccccgg cagcagattg agctggtggc tcgtgcgttg gataaaatgc
     4741 cacagggaga aaaactcaat gctgaactgg atgccatact gactcagacg gggagtacga
     4801 tccctaatat aaagcattat tcctttgcct atatcaaggc tggaacaaca ggtaacacct
     4861 tatccatcta tgtcaaaaat gatcccaggg ttgatacttt ggtacaccta ggcttgtcat
     4921 tgttgccatt ggcggattct ctgaccgctc cttttggtag ttttgcattc aatattggtc
     4981 tggagaacgc tgatttgttg aatggagcgg atattttagt tacctggtat accagtgaaa
     5041 aggagcgtca gcagacggaa gcacagcctc tgtttcgatc tattcgtgcc gtccgtgagg
     5101 gagggtatat tccgatgact gatcagtctc tcgtaatgtc aatgtcttat ggctcgctac
     5161 tgagtttgcg ttggggatta cccagattta tgccgttgtt gaagctggag atagcaaaac
     5221 atgagaaaca ctaagcaacg tctatctctc acattgggtt tggtgttgat ggcattactg
     5281 acctgtcttt gtgtcgccgt cagcttaagt ttgggatcga aatccctacc gctgtcagcc
     5341 atttggcagc attattggct aggggatcaa ggcagttatt atgatttggt tatcaatgct
     5401 cgtgagccgc gtacactcat tggtttaatg gccggagccg cactggcact tgcaggaact
     5461 gttactcaag gattgttacg taatccgttg ggagatcccg gtttgttggg aattaatgcg
     5521 ggggcggcga ccgcggtagt ctttttctct ttcattccag tgttggatca actgcctcgt
     5581 tttgggacag catttattgg cgctggctta tcaactttat tgttctacct gcttagcggg
     5641 ggttcccgca ataccaatcc tgtacgattg gttttgacag gagcagctat taatgcctcc
     5701 ctgtttgccg tggtacaggg aattgtactg atgaatgcac aggcaatgga cagttatcgt
     5761 ttttggacaa tgggttcttt gagcaccatg tcattaaggg aagcaagttt attgatccct
     5821 tatctgctgg tggctatcgt tttgacgctt tcactcagtg cttcattgaa tgtgatggtt
     5881 tttggtgaag ggatcgctgg ctctctcggt gccaatgttg cccgtacccg tatattgtca
     5941 ttattaagtg ccaccatgtt ggcggcagga gcgacagcca tggcgggccc gattgccttt
     6001 attggtctgg tggcaccaca tttgatgcgg gccttagtag gcagtgattt ccgctggttg
     6061 ctgccttact gcctgtttgc aggcccttgt ttgctattga tatcggatgt tgtgggacga
     6121 ttgctgatag cgccagagga gatcatggtt ggaattatta cagcagccct tggtgcaccg
     6181 ttgctttatc tggttgccaa aaaccggaca caaaaaataa tggtggaata gaagtatgac
     6241 gcagattgat tcgtcaacac caatcaggca gccacgtgtc agaacattcg cattgggaaa
     6301 ggccgttttt atcacaccat cgtggcagac aaggaaaatg gtattttcga tgttgctgtt
     6361 gttggtagtg cttttttatc tgaccttatc attaggcaga gaagggatgg ataacccttt
     6421 tctgacaacg gaaacacctt atcaggaatt tattctattg cagatacgtt tgcccagagc
     6481 gttgctagca attggagcgg gaatagcact ggctctttcg gggacactat ttcagctgac
     6541 tacccgcaat gcacttggta gcccagacat cattggtatt aatgccggag ccgcagtagg
     6601 tattatggca gcactgctta tctggcccgg tgtactgcca attcctttag gtggcttatt
     6661 gggagccggg cttgctgtgt tgttggttta tttcggtaat ggcgccggtc tgggaagaat
     6721 gcaaaccggg aaaatagtga tatccggggt tgcagttgct gcattttgta tggcaatggt
     6781 tgactttgct gtctcaaata tccgcataga gcaggctcag caaatacgtt cattactgat
     6841 aggtagtctt gccagcagag gatggcagga tgtgataact atcagtgggt tgataatttt
     6901 tactcccgta ttgttttggt tgggcaggca attaaattat acccattttg gcgatgacat
     6961 cgctaataca ctgggtgtgc cagtacgttt tatccagatt gttagcatat tgttggcagt
     7021 catttttgcc gccatgtctg tattagttgt cggccctgtt tcctttattg ccctttctgc
     7081 accacaaatt gcccatcgat tagtacatgc gaaaggagct gcattgtttt gctctgcttt
     7141 ggttggggct ttgctgatgt tgttgtctga tttaattacc ctgatattac caactccggc
     7201 tcgtttacct gtcggtttag ttactgcggt aattggtggg atctatttga tgtatttact
     7261 gtatgcagaa ttaaggagaa cacgataatg ccatcggatg agaattcccc tgtgacgact
     7321 tcacggctta aagccctgga tctttcactg gcatacggta aaagaacgat cattgacggt
     7381 attaatatcg cgattcacga tagtgaattt agtgtcatca ttggccccaa tggatgcgga
     7441 aaatcaacct tgttgcgggc gatcagccgc agtatgcagc cacagcaggg tgaggtccaa
     7501 cttgatggaa taaatatcca tcgctataag ccaaaagctg ttgcacgtga gttgtcatta
     7561 ttaacgcaag gggcagttat aactgaggcg ttgacaatct atgaccttgt ttcgcgtgga
     7621 cgttacgctt atcagacttt cttgcggcag tggtcagaag aagatgaacg tgtcgtcaat
     7681 gaagcattac gggcagtaga tttatgggat atgtcgcaga aattggttag tgaattgtca
     7741 ggtggtcagc gtcagcgcgc atggtttgcc atgacattgg cacagcaaac ccccattatc
     7801 ctgttggatg aaccgacgac ttatctggat atctctcatc aaattgagat gcttgatttg
     7861 tgtcagcgtt tacatcaaca agggaaaact ctggtactgg ttttacacga tatcaatttg
     7921 gctctacgtt atgccacacg gttaatcatg atgaagaacg ggcaagttta tgcagaaggc
     7981 aagccggaag aaatcatcac agaacaaagt attgcagatg tatttggtct ggcctgttgc
     8041 attattcgtg atccggaatc tgacaagccg ttagttattc cgagatataa caggagagtg
     8101 taaaatggca aataaaaata atcatagctc caatcaaatg atatcaaaaa tagatattaa
     8161 cgatattgtt aatttattcg acagtgcatt cagtcacttt aactcatcaa tgaaagtgaa
     8221 tgcgggaaat atcccatcag agagtatgga tttttatcaa tggtcgaatg aaaaagaatt
     8281 ctcattatta atgcagcgtt accaaaacga gtactatggg aataatgaac agaagccaaa
     8341 taataaaggt ctttattcgt tatgggcaca atggtatttt ggcttggttg ttcctcctat
     8401 tatgttaatg ttgttggaat atccacaggc agtagatgca gattaccatc tttttcaggt
     8461 tgaatttcat gaaagtggcc ggcctaatat ggtttattac cagttaaact ggatgaaaga
     8521 acctatatcc ctgctggaac gttattattc tttattggat cgccatatta ttcctgtttg
     8581 tgagaaaatt gaatcttatc ggggaattaa tgggcgttta ttatggaaca atattggtta
     8641 tgtgatgtat tggtatttga gtaatttcag ggaaagaatg gatgctgaac aatacaacat
     8701 attggtaaat aaccttttct ttgaacagaa attaccggat ggcagggata atccattgta
     8761 tcggacagtt attctgagaa ataatgtgat tcagcgtcgt tgctgctgtc aaagaaacaa
     8821 actaccggga gtaggaaatt gtcatgattg tcctcttgaa tcaactgcat aaatagtatt
     8881 aggttgaatt accttatttt ttaaaagaag gttatgattc tttcttttta tgactttgtt
     8941 aacttgattg ttaatagagg aattcatatt gtaaaaaata ctttaaaagg ttatctatat
     9001 accaaataga ttttattttt tgttaataat aagtaaggta tttccccgga acatatagaa
     9061 tatatgttca taattatgtt atcgggataa attagctaag ccagatagat aaaaattaaa
     9121 aattaaaaaa tgaaaagaat atctaatgaa tttagagcct aaatttagga atagtagact
     9181 aaagattaaa aaatatagag ctatatataa ctaggtttaa tgaacatagt tataagatca
     9241 ataagttaga atattaatgc tatagcttat ataaaaagta aggatatata atgtttgaag
     9301 aatctcaagt atttgccgaa tctttggcca aaaacaccta tttaacggga aatgataatt
     9361 ttaaaaatag cgatagcttt aaagaaaacc actttaatca atatctatta aatggtgata
     9421 atgcagggag ctacctagaa gattcctgcg atgtaattgt taagttaaaa aggatattgc
     9481 agaaaacaaa atctcctttt agcggaatat tacctaatga attatcttca tcatttaaaa
     9541 agataaattt agataaccca ttgggatctt gggaacatgc attagaagaa ttgcagcacc
     9601 tttatattaa agatgctgtt tatttccatc atcctaaata tgttgcacac cttaactgtc
     9661 cacttgtgct gccatcagcg atagctgaaa caataattgg ttgcataaac tcatctgtag
     9721 atacatggga tcaaagcgct ggagggacac tgatagaaca gaaagttctt gattggacgc
     9781 tggataagat tggtttaggt aaagaagcag atggcatatt taccagtggt ggtacgcaat
     9841 caaacctgat ggcaatgcta ttggcacggg actggttttg ccaccaacga aacccagggc
     9901 acaaaaacca actgcatggt ttacctgcgg attttcataa actacgtatt ttttcctcat
     9961 cggtgagcca cttcagcact caaaaagccg ctgcgatatt ggggttaggt tataacgctg
    10021 ttgtctctgt cccatgtgat gatgaattcc gaatgtctgt acaggcatta gaagcaaata
    10081 ttaaacaatg ttttgatgaa gggaatattc cttttgccat tgttgctact gcgggaacga
    10141 cagattttgg tagtatcgat ccattacctt tacttgctga tttagccgaa aagtacagtt
    10201 tatggttgca tgttgatgct gcttatggat gtggtctact ggtttcatcc cgccactctc
    10261 atttacttca gggcatagac agagcggatt ccgtcaccgt ggattaccac aaatcctttt
    10321 tccagcctgt aagttgcagt gctttcttcg ttaaaaataa acagcatttt tctcatctga
    10381 cctaccacgc ggagtatttg aaccctttga gtgcggaaca ggagggaacg ccgaatctgg
    10441 tgaataaaag catccagacg acgcgtcgtt ttgatgcact gaagatgtgg ctgacactgc
    10501 gcgtgattgg tgccgaacaa cttggacagg catttgatac tttattggac acggcacagt
    10561 ccgcgtatca tttgatgaga caaaacccat gttttgaact tgtccatcaa cctgtattaa
    10621 gtacgttggt atttcgcttt gtcccgaagc aaggattccc tgaatatgcg attgatcacc
    10681 ttaatgccaa catccgtaag gcactgttta gagaaggaga gtgtgttatt gctggcacta
    10741 aaatcaatga caggcaatat ctgaaattca cgttccttaa tccggctaca accgtaaaac
    10801 atttacaaga gatcatcgac agtattgtca ctcagggaaa cctgttactg accgatctcg
    10861 tattttctga tgattcatta ttcaatcaac atcaagctgt ttattgatca acttgtattt
    10921 attaggagta attatgacaa ccaagactta tgattttatc gcaattggag tcggcccatt
    10981 taatctgggg ttggcttgtc tggttcagcc tataaaagaa atcactagcc tgtttattga
    11041 tcagaaagca ggatttgatt ggcatccagg catgatgtta gaaaactcga ctatgcagac
    11101 tccgtttatg gcggatttgg taacattagc ttctccgaca catccattga gctttctcaa
    11161 ttatataaaa gagaagggac gtatttattc attctacatt cgggaaaact ttttcctgat
    11221 gcgcaaagaa tataaccaat actgtcaatg ggcagcggaa aaactttcta atcttcgttt
    11281 taacacaaag gttgaagata ttagttatga tgaagctcat tcgcattata ttttgcaatg
    11341 tgcggatact ttgacagggc agaaacacca attttttgca aaaaaattgg tgttaggaac
    11401 agggccttct tcttatattc caaagtgttg caagcccttc gaaaatcaaa tgataacatc
    11461 tggaaattat ttaagtaata aagcagcttt acagcaaaag aaatctatta cagttttagg
    11521 gagtggtcag agtgccgcag agatttttta tgatctgtta caggacgttg atacctatgg
    11581 ttatcaactc aattgggtca cacgctctcc tcgctttttc ccgcttgaat ataccaaact
    11641 gacattggag atgacttctc ctgaatatgt ggattatttc tatagtttgc cagaaaacaa
    11701 gcgtgaagaa ctcaatcgct cacaaaaatc tctctataaa ggtattaata gctcacttat
    11761 taatgaaatt ttcgatttga tgtacaccaa gcgattaaat ggagaattga atgtttcgtt
    11821 atataccaac agtgaattgc gagaaataca ttgcataact gaaaaccaga atacagtagt
    11881 aaaacaaaaa tttgtattgg atttattcca gcaggaacag gaagccctgt tttatctgga
    11941 aacagaagga gtcgttctgg ctacaggata tcaatatcag gttcctggat ttattgaggg
    12001 tattcagcaa cgtatccgtt gggataaacg aggtcgttat gatgtgcagc gcaattatag
    12061 tatcgactac aacaatgaaa tctttgtaca aaacgttgaa ctgcatacac atggctttgt
    12121 gacgccagac ttgggaatgg cctgttaccg caattctcgc ctgattgagg aaatcacggg
    12181 aaaagaacat tacgtgatag aaaaaagtat ttcattccaa caatttagtg ttgccagtga
    12241 aggagtatgc tgatgtttga tattgcccct atatcatttg aaaaaaaact acctgatttg
    12301 ggaacgtttt cattgcgtcc attagatata gatgaagaca ttgcggttat tacagattgg
    12361 gttaaccggg actacgcttg ttattgggga atgcaagatc atactgaaca gcaggtaaga
    12421 gatttctatc aagacttaat agaaaatcag cctgattctg tttttattgg aatatatcag
    12481 gaacaaccgg ttttcttgct ggagtgttat tgggcacaga aagatcagat cggccaatat
    12541 tatgatgccc tcccggatga catggggatg catatactgg ttgcgccatc agataagaag
    12601 atcaagcaat ttacgtgggg gatctttcaa acaattattg catttatttt cagtaattct
    12661 gctgttaatc gaatcgttgt tgagcctgat atacgaaatg aaaagatcca ccgcctcaat
    12721 ttacgagctg gttttgttta tcataaaact gtgcaattac cacacaaaac tgctggattg
    12781 gcattttgta cgagagaaca gcaccaaata gcgttgcaat cagcggaatt accggaaact
    12841 cttaatcaca gcgatgcttt cgttaggcac ttataccctg ccatttggca aaaagtgaac
    12901 cgattacatt tgaagaaagc catttctgag tttgcccacg agtgtctgtt atcgccagag
    12961 ctattgactg aaaccacaga ccaggatggt tatcggcatt atcacttaga aaataatgaa
    13021 cattcggttg attatcattt ccgtgcacgt cggttggcac ttgaccattg gcttattgat
    13081 gctgattcat tacgaaaaat gcaggcaggg gattgggttg aactcgattt cattcttttt
    13141 atcattgagt ttaaaaaaca gattggtatt agcgataccg tgatgccaac ttatttggaa
    13201 gaattgacca gtacattaca tagcagtgca ttcaaatatc atcggagtgg tattaaagta
    13261 gaagaattgg tcgatgctga ttttcaggct attgaagctg aaatgatgga aggtcatccg
    13321 atatttgtgg ctaataatgg acgtattggc tttgatgcgg aagatttcca aaattttagt
    13381 cctgaatctg ctgctgatat tcgtttgata tggttggctg cgcataagcg caaagcacat
    13441 tttgcctgca ttgaacaact tacttatcag caactattgg agcaggaatt aggcaaagag
    13501 gaggtcactc aatttaataa taaacttatt cttatgggtc ttaatccaga agaatattta
    13561 ttgatgcctt ttcatccatg gcaatggcaa aacaaactgc catcggtatt tgctcatgac
    13621 cttgctaacc gaaacttgat ttatttgggg aagggaagcg atatttatca ggctcagcag
    13681 tcaataagaa ctctttttaa tcgtagcaac ccacaacgct tctatgtaaa agcagcttta
    13741 tctattctga atatgggatt tatgcgtggt ttatcacctt attatatggc gaccacaccg
    13801 ggcataaatg aatggttgtt tgatttagta gaaaacgatg tggttttaca gcgttgtggt
    13861 tttcgactct tgagagaagt cgcgagcatt ggttttagga gtagttatta tgaacaggcc
    13921 attaatggtg atacacctta taagaaaatg atggctgcgt tatggagaga aaaccctctt
    13981 caactgattg aaaataatca gaatgtgatg tcgatggcag cattattgca tcatgatcaa
    14041 caggggaatg ctttcttacc cgctttaata tctgcctcag gattatctac ggatgagtgg
    14101 gtacgtcgtt atttgggctg ctatctgctg ccgctattgc attgtttgta tgcttacgat
    14161 ctgatgttca tgccacatgg tgaaaatatc attatggtgc ttgaggagca tataccgcaa
    14221 tacatcttta tgaaagattt ggcagaagaa attctggtga tgaatcctga tgctgatttg
    14281 ccagaaaagg ctagtcgggt gaaagtaaat atgccagaag aaatgaaatc attgactatt
    14341 ttatctgacg tatttgatgg agtttttcgc tacctgtcag caattcttga tgaacaaggt
    14401 ggatatccac aagacgattt ctggaaagcg gtagccgatt gtattttgga ttatcagttt
    14461 gagcatccag aacttaaaga aaaatttatt caatatgaac tgtttacacc agaaattaaa
    14521 cggtgctgtc tgaatcgtct gcaaattgct aataatcgtc aaatgttgga tttgtctgat
    14581 ccctctaaga gtttgaaatt ttctgaggaa ttgattaatc caattgctgt atttgtaaaa
    14641 actgctcata taaagtga
//
