BGC0001872 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001872 (Xenorhabdus bovienii SS-2004)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	hglE-KS,PUFA	1	20,491	fabclavine-polyamine	PKS	100%

BGC0001872 - Region 1 - PUFA,hglE-KS

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Location: 1 - 20,491 nt. (total: 20,491 nt) Show pHMM detection rules used

Region on contig edge.

hglE-KS: (hglE or hglD)
PUFA: PUFA_KS

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 20,492
Label		BGC0001872

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001872	2.00	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000863	0.59	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0002429	0.50	Terpene, Polyketide	higginsianin B	Colletotrichum higginsianum IMI 349063
BGC0002483	0.49	Polyketide	usnic acid	Cladonia uncialis subsp. uncialis
BGC0002648	0.49	Polyketide	eicosapentaenoic acid	Shewanella sp. N2AIL
BGC0000861	0.49	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0000284	0.47	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0001130	0.47	NRP, Polyketide	fabclavine Ia, fabclavine Ib, fabclavine IIa, fabclavine IIb	Xenorhabdus budapestensis
BGC0000056	0.47	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000862	0.47	Other	eicosapentaenoic acid	Shewanella pneumatophori

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001872	1.00	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000863	0.63	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0002429	0.59	Terpene, Polyketide	higginsianin B	Colletotrichum higginsianum IMI 349063
BGC0002483	0.58	Polyketide	usnic acid	Cladonia uncialis subsp. uncialis
BGC0002648	0.58	Polyketide	eicosapentaenoic acid	Shewanella sp. N2AIL
BGC0000861	0.58	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0000284	0.57	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0001130	0.57	NRP, Polyketide	fabclavine Ia, fabclavine Ib, fabclavine IIa, fabclavine IIb	Xenorhabdus budapestensis
BGC0000056	0.57	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000862	0.57	Other	eicosapentaenoic acid	Shewanella pneumatophori

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 20491:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

XBJ1_2946

AMP-binding (35..212): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DELICDP-DK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

XBJ1_2953

PKS_AT (593..896): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 41.5
Methoxymalonyl-CoA: 26.3
Methylmalonyl-CoA: 19.9
Acetyl-CoA: 19.1
fatty_acid: 10.8
Benzoyl-CoA: 9.0
inactive: 8.2
trans-1,2-CPDA: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0