BGC0001874: α-cyclopiazonic acid biosynthetic gene cluster from Aspergillus flavus
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Location: 1 - 16,901 nt. (total: 16,901 nt).
This entry is originally from NCBI GenBank JN712211.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001874
Short description α-cyclopiazonic acid biosynthetic gene cluster from Aspergillus flavus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
JN712211.1
via Knock-out studies
Compounds
  • α-cyclopiazonic acid
Species Aspergillus flavus [taxonomy]
References
Chemical products information
α-cyclopiazonic acid Evidence: NMR [1]
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C20H20N2O3
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFA26383.1
  • maoA
 441 - 1808 (+) monoamine oxidase
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    • AFA26385.1
    • dmaT
    		 2306 - 3676 (-) dimethylallyl tryptophan synthase
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      • AFA26384.1
      • cpaA
      		 4655 - 16375 (+) polyketide synthase A
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        Biosynthesis information

        Biosynthetic modules

        Name
        Unk01
        Type
        nrps-type1
        Genes
        cpaA
        Substrates
        tryptophan (evidence: Structure-based inference, Feeding study)
        Integrated Monomers
        Domains
        adenylation
        Annotation changelog

        Entry version: next

        Date
        Changes
        Submitters
        Reviewers
        2024-05-18
        MIBiG v4 annotathon
        • (ID: WGYEEFADVXA7X4KRF2R4CDK4)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 3

        Date
        Changes
        Submitters
        Reviewers
        2022-10-07
        Update chemical activity to schema version 2.11
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 2

        Date
        Changes
        Submitters
        Reviewers
        2022-09-15
        Added NRP substrate specificities
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 1

        Date
        Changes
        Submitters
        Reviewers
        2019-10-16
        Submitted
        • (ID: RZXXEFYXH3WXN74YX6LRS5EA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        Detailed domain annotation
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