LOCUS       BGC0001878             15780 bp    DNA     linear   BCT 28-NOV-2019
DEFINITION  TPA_exp: Streptomyces sp. NRRL B-1347 detoxin N2,N3 biosynthetic
            gene cluster, complete sequence.
ACCESSION   BGC0001878
VERSION     BGC0001878
KEYWORDS    .
SOURCE      Streptomyces sp. NRRL B-1347
  ORGANISM  Streptomyces sp. NRRL B-1347
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     THIRD PARTY DATABASE: This TPA record uses data from
            DDBJ/EMBL/GenBank entry JOJM01000013.1
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 05:12:25
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..15780
                     /db_xref="taxon:1476877"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. NRRL B-1347"
                     /strain="NRRL B-1347"
     misc_feature    1..15780
                     /note="detoxin N2,N3 biosynthetic gene cluster"
     protocluster    1..15780
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[37:13038]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      38..13038
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..15780
                     /SMILES="NC(C(C)CC)C(=O)N1C(CCC1)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..15780
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001878"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15780
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            38..3898
                     /gene="detF"
     CDS             38..3898
                     /NRPS_PKS="Domain: Condensation_LCL (2-290). E-value:
                     2e-101. Score: 330.7. Matches aSDomain:
                     nrpspksdomains_detF_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (453-845). E-value: 1e-102.
                     Score: 335.6. Matches aSDomain:
                     nrpspksdomains_detF_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (955-1023). E-value: 9.3e-18. Score:
                     56.1. Matches aSDomain: nrpspksdomains_detF_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1043-1263). E-value:
                     2e-31. Score: 102.0. Matches aSDomain:
                     nrpspksdomains_detF_Thioesterase.1"
                     /codon_start=1
                     /gene="detF"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     366.3; E-value: 3.4e-111)"
                     /gene_kind="biosynthetic"
                     /product="peptide synthetase"
                     /protein_id="DAC80528.1"
                     /sec_met_domain="Condensation (E-value: 2.8e-67, bitscore:
                     215.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7e-116, bitscore:
                     375.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-13, bitscore:
                     39.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGASEAYHLPTAVELRGALDRTALSRALDALVARHEVLRTRLEA
                     VAGAAVQRIDPPGAGLPLATDDLTGLPDAEAEAELARVRREEAAAPFDPARGPLLRGRL
                     VVLGADRHVLLLTVHHLVSDDWSMDVLTREVGALYAAFREGAPDPLPPLPAQYADYAAW
                     QRQWLADPSPDGAAARQSAYWRQALADAPAVLQLPTDRPRPAEQDYRGGRVELAFDEEL
                     TAALKDLGGRDGASLSTTVLAAWALVVARAAGQSDVVIGTPTANRRGAELEGLIGCFAN
                     TLALRIDVSDDLTVAGLLDRARTATLSALRHQDLPFEQVVDLVKPVRSLAHTPLFQVMF
                     DWNGTERAAWALPGLEATPLAPPRQVAEFDLTLSLAEEGGRLTGALGYATALFDAATAE
                     RYGRQLRHVLEQLAAGPDTPVAEVTLLDDRARRQVLVDFNDTARAGSPAGLVERFEAQV
                     RERPGQTAVVHGGDALDYATLERRANRLAHALIARGIGTDRVVGLHTHLSVDLLVGILG
                     VLKAGGAYLPLDPALPAERLAGMVADADALLVLSNDAAPPDDAWLPLTAVEAEGARDDA
                     PGRGFRPDDLAYVIYTSGSTGRPKGVAATHRGILNLLDYWLGQFDATPGQASAMWPSFA
                     FDASVQELLLPLTSGGVLQLVPKEVRDDPEALLDWMREHRIVEALLPPAYVKWICEAPE
                     ERLAGLSLRYIHTGLEPLPEDSLHRMTQVLPGLHILNGYGPTETALYCTAYLTPQPLER
                     QAPIGPPVANTRTYVLDERLRPVPVGVVGELYIAGAGMARGYLGRPDLTAERFVADPFV
                     PGARMYRSGDLVRWLPDGNLLYAGRRDHQVKVRGFRIELGEIEATLLDQPGVSEAAVIA
                     DRDGAGEPQLVAAVGVGDAAPRPAAEWRAALAQRLPAHMIPGIFVEVPRLPQTQNGKLD
                     RAALLERARADRPAQVNLASPRDHIELTLYQIWRSLLLQPDIGIRDSFFDIGGTSISAI
                     KLVHAIREAFGETLLVREVMLHPTIEELGGRLRRGASGAPPSNLLQFRPGDGDAHVVCV
                     HPAGGTAFCYLSLAKALPENVGVHGIQSPGVNPGETFLPTVEAMAEAYLKLIEPLSGGP
                     LILTGLSYGGLVVHEMGRLLAAAGHRDVSVVLLDAQGAGNAEQRANITTVDMAEFRDKL
                     VKFNGMYPGIDDRQIEQYFHIYNHNRTTAVAYDPRPTAARTVFLQAVEGATDQFLADVR
                     DFWRDRADGDFEVESIACDHWGMLESAEILRVAARIESELARFAGSAKPRLAESAPARE
                     AE"
     aSDomain        44..907
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detF_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.00E-101"
                     /label="detF_Condensation_LCL.1"
                     /locus_tag="detF"
                     /protein_end="290"
                     /protein_start="2"
                     /score="330.7"
                     /tool="antismash"
                     /translation="GASEAYHLPTAVELRGALDRTALSRALDALVARHEVLRTRLEAVA
                     GAAVQRIDPPGAGLPLATDDLTGLPDAEAEAELARVRREEAAAPFDPARGPLLRGRLVV
                     LGADRHVLLLTVHHLVSDDWSMDVLTREVGALYAAFREGAPDPLPPLPAQYADYAAWQR
                     QWLADPSPDGAAARQSAYWRQALADAPAVLQLPTDRPRPAEQDYRGGRVELAFDEELTA
                     ALKDLGGRDGASLSTTVLAAWALVVARAAGQSDVVIGTPTANRRGAELEGLIGCFANTL
                     ALRIDVS"
     aSModule        44..3826
                     /complete
                     /domains="nrpspksdomains_detF_Condensation_LCL.1"
                     /domains="nrpspksdomains_detF_AMP-binding.1"
                     /domains="nrpspksdomains_detF_PCP.1"
                     /domains="nrpspksdomains_detF_Thioesterase.1"
                     /final_module
                     /locus_tags="detF"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       56..163
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0001"
                     /evalue="6.90E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="detF"
                     /protein_end="42"
                     /protein_start="6"
                     /score="57.0"
                     /tool="antismash"
                     /translation="AYHLPTAVELRGALDRTALSRALDALVARHEVLRTR"
     CDS_motif       389..454
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0002"
                     /evalue="8.40E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="detF"
                     /protein_end="139"
                     /protein_start="117"
                     /score="31.1"
                     /tool="antismash"
                     /translation="VHHLVSDDWSMDVLTREVGALY"
     CDS_motif       503..541
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0003"
                     /evalue="9.30E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="detF"
                     /protein_end="168"
                     /protein_start="155"
                     /score="18.1"
                     /tool="antismash"
                     /translation="QYADYAAWQRQWL"
     CDS_motif       806..895
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0004"
                     /evalue="3.30E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="detF"
                     /protein_end="286"
                     /protein_start="256"
                     /score="51.6"
                     /tool="antismash"
                     /translation="DVVIGTPTANRRGAELEGLIGCFANTLALR"
     CDS_motif       944..1063
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0005"
                     /evalue="1.30E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="detF"
                     /protein_end="342"
                     /protein_start="302"
                     /score="65.8"
                     /tool="antismash"
                     /translation="RTATLSALRHQDLPFEQVVDLVKPVRSLAHTPLFQVMFDW"
     CDS_motif       1196..1240
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0006"
                     /evalue="3.50E+01"
                     /label="C3_starter_134-155"
                     /locus_tag="detF"
                     /protein_end="401"
                     /protein_start="386"
                     /score="-2.2"
                     /tool="antismash"
                     /translation="GYATALFDAATAERY"
     aSDomain        1397..2572
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detF_AMP-binding.1"
                     /evalue="1.00E-102"
                     /label="detF_AMP-binding.1"
                     /locus_tag="detF"
                     /protein_end="845"
                     /protein_start="453"
                     /score="335.6"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEAQVRERPGQTAVVHGGDALDYATLERRANRLAHALIARGIGTD
                     RVVGLHTHLSVDLLVGILGVLKAGGAYLPLDPALPAERLAGMVADADALLVLSNDAAPP
                     DDAWLPLTAVEAEGARDDAPGRGFRPDDLAYVIYTSGSTGRPKGVAATHRGILNLLDYW
                     LGQFDATPGQASAMWPSFAFDASVQELLLPLTSGGVLQLVPKEVRDDPEALLDWMREHR
                     IVEALLPPAYVKWICEAPEERLAGLSLRYIHTGLEPLPEDSLHRMTQVLPGLHILNGYG
                     PTETALYCTAYLTPQPLERQAPIGPPVANTRTYVLDERLRPVPVGVVGELYIAGAGMAR
                     GYLGRPDLTAERFVADPFVPGARMYRSGDLVRWLPDGNLLYAGRRDHQVKVR"
     CDS_motif       1583..1624
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0007"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="detF"
                     /protein_end="529"
                     /protein_start="515"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LGVLKAGGAYLPLD"
     CDS_motif       1796..1855
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0008"
                     /evalue="6.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="detF"
                     /protein_end="606"
                     /protein_start="586"
                     /score="31.0"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAATH"
     CDS_motif       2366..2455
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0009"
                     /evalue="2.90E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="detF"
                     /protein_end="806"
                     /protein_start="776"
                     /score="57.9"
                     /tool="antismash"
                     /translation="PVGVVGELYIAGAGMARGYLGRPDLTAERF"
     CDS_motif       2537..2602
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0010"
                     /evalue="5.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="detF"
                     /protein_end="855"
                     /protein_start="833"
                     /score="37.7"
                     /tool="antismash"
                     /translation="YAGRRDHQVKVRGFRIELGEIE"
     aSDomain        2903..3106
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detF_PCP.1"
                     /evalue="9.30E-18"
                     /label="detF_PCP.1"
                     /locus_tag="detF"
                     /protein_end="1023"
                     /protein_start="955"
                     /score="56.1"
                     /tool="antismash"
                     /translation="ELTLYQIWRSLLLQPDIGIRDSFFDIGGTSISAIKLVHAIREAFG
                     ETLLVREVMLHPTIEELGGRLRR"
     aSDomain        3167..3826
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detF_Thioesterase.1"
                     /evalue="2.00E-31"
                     /label="detF_Thioesterase.1"
                     /locus_tag="detF"
                     /protein_end="1263"
                     /protein_start="1043"
                     /score="102.0"
                     /tool="antismash"
                     /translation="HVVCVHPAGGTAFCYLSLAKALPENVGVHGIQSPGVNPGETFLPT
                     VEAMAEAYLKLIEPLSGGPLILTGLSYGGLVVHEMGRLLAAAGHRDVSVVLLDAQGAGN
                     AEQRANITTVDMAEFRDKLVKFNGMYPGIDDRQIEQYFHIYNHNRTTAVAYDPRPTAAR
                     TVFLQAVEGATDQFLADVRDFWRDRADGDFEVESIACDHWGMLESAEILRVAARIES"
     CDS_motif       3353..3418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detF_0011"
                     /evalue="7.00E-05"
                     /label="NRPS-te1"
                     /locus_tag="detF"
                     /protein_end="1127"
                     /protein_start="1105"
                     /score="15.4"
                     /tool="antismash"
                     /translation="GPLILTGLSYGGLVVHEMGRLL"
     gene            3895..13038
                     /gene="detG"
     CDS             3895..13038
                     /EC_number="2.3.1.39"
                     /NRPS_PKS="Domain: AMP-binding (19-413). E-value: 1.4e-86.
                     Score: 282.4. Matches aSDomain:
                     nrpspksdomains_detG_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (524-590). E-value: 5.6e-08. Score:
                     24.8. Matches aSDomain: nrpspksdomains_detG_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (612-904). E-value:
                     1e-61. Score: 200.4. Matches aSDomain:
                     nrpspksdomains_detG_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1063-1467). E-value:
                     7.5e-79. Score: 257.0. Matches aSDomain:
                     nrpspksdomains_detG_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1572-1640). E-value: 5.8e-12.
                     Score: 37.5. Matches aSDomain: nrpspksdomains_detG_PCP.2"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (1663-2070). E-value:
                     4.1e-129. Score: 423.0. Matches aSDomain:
                     nrpspksdomains_detG_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_KR (2461-2635). E-value: 5.1e-34.
                     Score: 109.6. Matches aSDomain:
                     nrpspksdomains_detG_PKS_KR.1"
                     /NRPS_PKS="Domain: PP-binding (2724-2783). E-value:
                     3.6e-12. Score: 38.5. Matches aSDomain:
                     nrpspksdomains_detG_PP-binding.1"
                     /NRPS_PKS="Domain: Thioesterase (2808-3030). E-value:
                     5.6e-23. Score: 74.4. Matches aSDomain:
                     nrpspksdomains_detG_Thioesterase.1"
                     /codon_start=1
                     /db_xref="GO:0004314"
                     /gene="detG"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 272.9; E-value:
                     8.2e-83)"
                     /gene_kind="biosynthetic"
                     /product="malonyl CoA-acyl carrier protein transacylase"
                     /protein_id="DAC80529.1"
                     /sec_met_domain="Condensation (E-value: 8.3e-49, bitscore:
                     154.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1e-95, bitscore:
                     309.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.3e-13, bitscore:
                     38.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 3.8e-130, bitscore:
                     423.0, seeds: 2284, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIAAPVPSSAPTLARAVLDRARRHPDAVAVVEGERSRTYGELDT
                     ASAAVAAALRHHGVRPGQAVAVGLPRSWELVCAMLGALRAGAVVVPLDAQSPADRRAHI
                     LTDSASVAVIHGAAAPDALPDGVRPLPVAALLDGGHGASHELAPAAPVSFVFYTSGTTG
                     QPKGVEVRDAGVLRLARPGYVETHEGAGFACMSNPAFDAISFEVWVPLLTGGRCVLLDD
                     GTVQDPEVLAAALERLRVDIVFITVALFNAVVDKVPHCFSSVGQVLTGGEQLNARLIRR
                     WYRDNADSGTRLHNVYGPTEATTFALCHPIPRDFDGDVVPIGRALPGTETLLVAADGSR
                     AAAPGEVAELYLAGEALAAGYRNLPEETERRFVTLPWHEDGSRRHYRTGDLVRLDAAGD
                     VAYVERADRQVKVRGFRVEPGELERQIVAHPAVRQAYVCTRRDASGVNELLAYLVLGAD
                     LAYDDFDAHLAASLPAYMRPHRAYLIDALPLNANGKVDRAALLRRPDAPWRRADEPGAA
                     EAVTDRQREVLDLAGEVLGLTGLRLADRWIACGGDSLKALRLRFEARRRWGCELPQALV
                     LHGDFAQLAAAVEAGRDADGTGGSPYPAAPAPAGARSAPATSEQQRLWLLHQRDPASRA
                     YHVPMVFRVDGDVDTGALRRALSRLVERHPALRTAFEATPEGVRQVVAEPYDPWTEPDA
                     QALRDEDGRRAFTARFLAAPFDLARPRLFRACWLPRTGGGELLLLLHHIAVDGWSLNVL
                     FRELSADYAHDGEAPEQQTRPAPTPLDYATWQSEWFSREAYRTQRAELRAHYAESADAA
                     PDSAPLEPVRPDERAGLLHTTLDADRRAALDRLCAELGLTRFQLLLGVYAWSLYGVTGR
                     ARPRIAGPVANRPVQDFEASVGMFANTVLLPLDLAPGERLRTQLRQHGAAARAVLDRQD
                     VALADALADRGAGAGGAPFDFLFVLENTDFDAFALPGCATRPEWPVPDRAKCPLTLSVI
                     ERGTGFDCLWEYDAAHFDTAQLAALDALFRQALDQLADGSDTTLAELVAPYRRALPELG
                     RSTAEPLPFTTVAEGFARQARRTPDAPALAAGDRTVTYAELDAHAAALAAELSERHPVV
                     PGSPCHVALYFQPSVEHVVALLALARLNLTAVPLDPTYPPGLLRQILEQVEPLCVLVTP
                     GDEAALAALAPEDLPRHVVTAAAAAVEPVEQLPPHAGARPLYTLFTSGSTGTPKGVQVP
                     DLTMCNLLQWQRTSGGLTAPAATQQFSMLSFDVSFQEIYSTLCGGGTLHLVRPGWRQDA
                     PALLDQLDSAGIERLFLPYVALQVLAEHAVRLGRYPARLREVITAGEQLLCTDAIRTWF
                     AGLRGARLFNHYGPSETHVVSALCLEGDPAGWPERPAIGTAVTGAWLRVVDEAGQTVPP
                     GCPGRLLVGGPMVVPCYLNAPALNAERFVELPGLGTFYRSGDVARFDHDGLLHYLGRDD
                     QQIKLSGHRLELGQVEAALLRHPDVANAVVARDEDARLVACLECPGHVPSPEDLARHLA
                     PLLPAYVRIDRFRRLARLPLTPSGKLDRRAVLTAPGDELRPRGGAAPALSAREARLTEL
                     FEAVLGRPVGPEQRFFDAGATSLDLMRFHLRCGAEPGLDFTIPDLFEHVTIRSLARFLD
                     QGSAAAATSAPGSAAPGPEGLADEPIAVIGMAVRLPGADDLAAFWDLVRSGGRGMEHFD
                     AADGLVGARSQMSGLLGFDPEHFGISRQEARLMDPQQRHLLMSSVQALAHAGIADPAGR
                     RVGIVAGCGENTYHQSLVREADPERLPDSFQMALHHDKDFLTTKVAYHLDLTGPAFTVQ
                     AACASSLVAVHVAAGLLRQGDADVMLAGGVLVDTLLTDGYRYRPQHIFSKDGHCRPFSD
                     DASGTIGASGVGVVVLKPLRLARRDGDTVYAVITGSALNNDGSGKLSYSAPSLPGQREV
                     IRTALRRSGRTSADLGYVEAHGTGTQLGDPVEVGALRQAFDLAGADRCALTSVKSQIGH
                     LGAAAGVVGLVRAALAVHHGVIPPNVDFHQLNPKLGPDIAPFYVPTRTLPWPDARPRVA
                     AVSSFGIGGTNAHLVLEAADAPDTAAEHTAVPCLLLSSSSAEGLRADADRLASYLEARP
                     EAYGEVLRHLQAGRTPRRWRAAAVHADVTAAVAWLRTASGVEVTPDDEPCPAAGRTAAE
                     LADAWLSGRTVHWPEGPAQAPWDFPPPVFRLATYDFERAAEPRAAAAGPQRLPEADWLH
                     QPQWTRLTRAARTAASGTLRLLVVMTAEPLPPEAMRVFGAAYERVVRVEAAGAFARLAD
                     DVYAVDPADADSLRELFDALGDAAGAGIDWLHALPLTVAGPVGETSLERARWACLDTPA
                     ALVQAAGSLSLRPWWLSYGAQPVNGDVRRPELGLLAGAGEVVPQESGVDGRWLDLPGAA
                     PADWAVAVVGLLRGADAATDLPRRLALRQGYWWRQALLPVPAPALAAPAALSVAPGGTY
                     VILGGTGGIGCALAAWLLTHADCRVVLLSRSGRLPSDLAQWADRVDLVEADLATAAADD
                     VLALIERHTGRVDGVVHAAGAAGGGLIARRDGDAMRWVTAAKLGGALLVERLIERHRPE
                     FAVYCSSMAALFGGIGQFDYAASGGLLDGFARYRSDADEATLRIGIDWDIWSEVGMARD
                     ALRSDARHQAHLAFGLAVKEGQRLFERALHLQLPQLLVSTTDIERVRDFYAPPADPAAA
                     PAVGQPTTADAGPAAADTGALAGWLRDALGLDDLDPDASLYDHGADSLTLIDLIAEVDE
                     RFGVDIELSRLSHRVSLNEVLTHLGEVAPATTAEPVTLEVWQEGTGHEVVCLVHPVGGD
                     IQAYRALVSALDDRLTVCLIADPALRAAEPPVWSLAERARRYHAALQARFPHGTWRWRL
                     AGWSFGAWVAQAMAADAEAAGRPAAGLYLLDPPPPDAGAHFRAYDDTRLEAVFAHELNQ
                     GGGAARASAGATAYAERLARCCRANIAGMAEHEPPALAATPTWLWLATRPVAGLPALGA
                     PDRQQRLWQERLPALQECHPLDTTHYDIVRAPRVLTVADTVNATSAPVPEDR"
     aSDomain        3952..5133
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_AMP-binding.1"
                     /evalue="1.40E-86"
                     /label="detG_AMP-binding.1"
                     /locus_tag="detG"
                     /protein_end="413"
                     /protein_start="19"
                     /score="282.4"
                     /specificity="consensus: ile"
                     /tool="antismash"
                     /translation="DRARRHPDAVAVVEGERSRTYGELDTASAAVAAALRHHGVRPGQA
                     VAVGLPRSWELVCAMLGALRAGAVVVPLDAQSPADRRAHILTDSASVAVIHGAAAPDAL
                     PDGVRPLPVAALLDGGHGASHELAPAAPVSFVFYTSGTTGQPKGVEVRDAGVLRLARPG
                     YVETHEGAGFACMSNPAFDAISFEVWVPLLTGGRCVLLDDGTVQDPEVLAAALERLRVD
                     IVFITVALFNAVVDKVPHCFSSVGQVLTGGEQLNARLIRRWYRDNADSGTRLHNVYGPT
                     EATTFALCHPIPRDFDGDVVPIGRALPGTETLLVAADGSRAAAPGEVAELYLAGEALAA
                     GYRNLPEETERRFVTLPWHEDGSRRHYRTGDLVRLDAAGDVAYVERADRQVKVR"
     aSModule        3952..5664
                     /complete
                     /domains="nrpspksdomains_detG_AMP-binding.1"
                     /domains="nrpspksdomains_detG_PCP.1"
                     /locus_tags="detG"
                     /monomer_pairings="ile -> ile"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4132..4173
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0001"
                     /evalue="1.80E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="detG"
                     /protein_end="93"
                     /protein_start="79"
                     /score="8.9"
                     /tool="antismash"
                     /translation="LGALRAGAVVVPLD"
     CDS_motif       4201..4236
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0002"
                     /evalue="1.30E+01"
                     /label="C3_LCL_132-143"
                     /locus_tag="detG"
                     /protein_end="114"
                     /protein_start="102"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="HILTDSASVAVI"
     CDS_motif       4354..4404
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0003"
                     /evalue="5.30E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="detG"
                     /protein_end="170"
                     /protein_start="153"
                     /score="19.1"
                     /tool="antismash"
                     /translation="FVFYTSGTTGQPKGVEV"
     CDS_motif       4924..5010
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0004"
                     /evalue="6.20E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="detG"
                     /protein_end="372"
                     /protein_start="343"
                     /score="28.2"
                     /tool="antismash"
                     /translation="PGEVAELYLAGEALAAGYRNLPEETERRF"
     CDS_motif       5098..5163
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0005"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="detG"
                     /protein_end="423"
                     /protein_start="401"
                     /score="29.9"
                     /tool="antismash"
                     /translation="YVERADRQVKVRGFRVEPGELE"
     aSDomain        5467..5664
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PCP.1"
                     /evalue="5.60E-08"
                     /label="detG_PCP.1"
                     /locus_tag="detG"
                     /protein_end="590"
                     /protein_start="524"
                     /score="24.8"
                     /tool="antismash"
                     /translation="REVLDLAGEVLGLTGLRLADRWIACGGDSLKALRLRFEARRRWGC
                     ELPQALVLHGDFAQLAAAVEA"
     aSDomain        5731..6606
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.00E-61"
                     /label="detG_Condensation_LCL.1"
                     /locus_tag="detG"
                     /protein_end="904"
                     /protein_start="612"
                     /score="200.4"
                     /tool="antismash"
                     /translation="SAPATSEQQRLWLLHQRDPASRAYHVPMVFRVDGDVDTGALRRAL
                     SRLVERHPALRTAFEATPEGVRQVVAEPYDPWTEPDAQALRDEDGRRAFTARFLAAPFD
                     LARPRLFRACWLPRTGGGELLLLLHHIAVDGWSLNVLFRELSADYAHDGEAPEQQTRPA
                     PTPLDYATWQSEWFSREAYRTQRAELRAHYAESADAAPDSAPLEPVRPDERAGLLHTTL
                     DADRRAALDRLCAELGLTRFQLLLGVYAWSLYGVTGRARPRIAGPVANRPVQDFEASVG
                     MFANTVLLPLD"
     aSModule        5731..8814
                     /complete
                     /domains="nrpspksdomains_detG_Condensation_LCL.1"
                     /domains="nrpspksdomains_detG_AMP-binding.2"
                     /domains="nrpspksdomains_detG_PCP.2"
                     /locus_tags="detG"
                     /monomer_pairings="pro -> pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5797..5907
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0006"
                     /evalue="1.50E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="detG"
                     /protein_end="671"
                     /protein_start="634"
                     /score="55.9"
                     /tool="antismash"
                     /translation="AYHVPMVFRVDGDVDTGALRRALSRLVERHPALRTAF"
     CDS_motif       6112..6171
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0007"
                     /evalue="4.40E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="detG"
                     /protein_end="759"
                     /protein_start="739"
                     /score="32.0"
                     /tool="antismash"
                     /translation="LHHIAVDGWSLNVLFRELSA"
     CDS_motif       6232..6261
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0008"
                     /evalue="1.50E-02"
                     /label="C4_LCL_164-176"
                     /locus_tag="detG"
                     /protein_end="789"
                     /protein_start="779"
                     /score="8.2"
                     /tool="antismash"
                     /translation="DYATWQSEWF"
     CDS_motif       6529..6594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0009"
                     /evalue="3.30E-07"
                     /label="C5_LCL_267-296"
                     /locus_tag="detG"
                     /protein_end="900"
                     /protein_start="878"
                     /score="22.8"
                     /tool="antismash"
                     /translation="PVANRPVQDFEASVGMFANTVL"
     aSDomain        7084..8295
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_AMP-binding.2"
                     /evalue="7.50E-79"
                     /label="detG_AMP-binding.2"
                     /locus_tag="detG"
                     /protein_end="1467"
                     /protein_start="1063"
                     /score="257.0"
                     /specificity="consensus: pro"
                     /tool="antismash"
                     /translation="FARQARRTPDAPALAAGDRTVTYAELDAHAAALAAELSERHPVVP
                     GSPCHVALYFQPSVEHVVALLALARLNLTAVPLDPTYPPGLLRQILEQVEPLCVLVTPG
                     DEAALAALAPEDLPRHVVTAAAAAVEPVEQLPPHAGARPLYTLFTSGSTGTPKGVQVPD
                     LTMCNLLQWQRTSGGLTAPAATQQFSMLSFDVSFQEIYSTLCGGGTLHLVRPGWRQDAP
                     ALLDQLDSAGIERLFLPYVALQVLAEHAVRLGRYPARLREVITAGEQLLCTDAIRTWFA
                     GLRGARLFNHYGPSETHVVSALCLEGDPAGWPERPAIGTAVTGAWLRVVDEAGQTVPPG
                     CPGRLLVGGPMVVPCYLNAPALNAERFVELPGLGTFYRSGDVARFDHDGLLHYLGRDDQ
                     QIKLS"
     CDS_motif       7516..7569
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0010"
                     /evalue="6.40E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="detG"
                     /protein_end="1225"
                     /protein_start="1207"
                     /score="21.9"
                     /tool="antismash"
                     /translation="YTLFTSGSTGTPKGVQVP"
     CDS_motif       8095..8184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0011"
                     /evalue="1.80E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="detG"
                     /protein_end="1430"
                     /protein_start="1400"
                     /score="33.0"
                     /tool="antismash"
                     /translation="PPGCPGRLLVGGPMVVPCYLNAPALNAERF"
     CDS_motif       8260..8325
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0012"
                     /evalue="1.50E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="detG"
                     /protein_end="1477"
                     /protein_start="1455"
                     /score="23.8"
                     /tool="antismash"
                     /translation="YLGRDDQQIKLSGHRLELGQVE"
     aSDomain        8611..8814
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PCP.2"
                     /evalue="5.80E-12"
                     /label="detG_PCP.2"
                     /locus_tag="detG"
                     /protein_end="1640"
                     /protein_start="1572"
                     /score="37.5"
                     /tool="antismash"
                     /translation="EARLTELFEAVLGRPVGPEQRFFDAGATSLDLMRFHLRCGAEPGL
                     DFTIPDLFEHVTIRSLARFLDQG"
     aSDomain        8884..10104
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="4.10E-129"
                     /label="detG_PKS_KS.1"
                     /locus_tag="detG"
                     /protein_end="2070"
                     /protein_start="1663"
                     /score="423.0"
                     /tool="antismash"
                     /translation="IAVIGMAVRLPGADDLAAFWDLVRSGGRGMEHFDAADGLVGARSQ
                     MSGLLGFDPEHFGISRQEARLMDPQQRHLLMSSVQALAHAGIADPAGRRVGIVAGCGEN
                     TYHQSLVREADPERLPDSFQMALHHDKDFLTTKVAYHLDLTGPAFTVQAACASSLVAVH
                     VAAGLLRQGDADVMLAGGVLVDTLLTDGYRYRPQHIFSKDGHCRPFSDDASGTIGASGV
                     GVVVLKPLRLARRDGDTVYAVITGSALNNDGSGKLSYSAPSLPGQREVIRTALRRSGRT
                     SADLGYVEAHGTGTQLGDPVEVGALRQAFDLAGADRCALTSVKSQIGHLGAAAGVVGLV
                     RAALAVHHGVIPPNVDFHQLNPKLGPDIAPFYVPTRTLPWPDARPRVAAVSSFGIGGTN
                     AHLVLEAA"
     aSModule        8884..12984
                     /domains="nrpspksdomains_detG_PKS_KS.1"
                     /domains="nrpspksdomains_detG_PKS_KR.1"
                     /domains="nrpspksdomains_detG_PP-binding.1"
                     /domains="nrpspksdomains_detG_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="detG"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       9319..9366
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0013"
                     /evalue="1.10E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="detG"
                     /protein_end="1824"
                     /protein_start="1808"
                     /score="14.6"
                     /tool="antismash"
                     /translation="GPAFTVQAACASSLVA"
     CDS_motif       9742..9789
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0014"
                     /evalue="1.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="detG"
                     /protein_end="1965"
                     /protein_start="1949"
                     /score="13.7"
                     /tool="antismash"
                     /translation="YVEAHGTGTQLGDPVE"
     aSDomain        11278..11799
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PKS_KR.1"
                     /evalue="5.10E-34"
                     /label="detG_PKS_KR.1"
                     /locus_tag="detG"
                     /protein_end="2635"
                     /protein_start="2461"
                     /score="109.6"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="GTYVILGGTGGIGCALAAWLLTHADCRVVLLSRSGRLPSDLAQWA
                     DRVDLVEADLATAAADDVLALIERHTGRVDGVVHAAGAAGGGLIARRDGDAMRWVTAAK
                     LGGALLVERLIERHRPEFAVYCSSMAALFGGIGQFDYAASGGLLDGFARYRSDADEATL
                     RIGIDWDIWSE"
     CDS_motif       11281..11379
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0015"
                     /evalue="6.80E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="detG"
                     /protein_end="2495"
                     /protein_start="2462"
                     /score="34.8"
                     /tool="antismash"
                     /translation="TYVILGGTGGIGCALAAWLLTHADCRVVLLSRS"
     CDS_motif       11638..11742
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0016"
                     /evalue="5.60E-11"
                     /label="PKSI-KR_m4"
                     /locus_tag="detG"
                     /protein_end="2616"
                     /protein_start="2581"
                     /score="35.0"
                     /tool="antismash"
                     /translation="EFAVYCSSMAALFGGIGQFDYAASGGLLDGFARYR"
     aSDomain        12067..12243
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_PP-binding.1"
                     /evalue="3.60E-12"
                     /label="detG_PP-binding.1"
                     /locus_tag="detG"
                     /protein_end="2783"
                     /protein_start="2724"
                     /score="38.5"
                     /tool="antismash"
                     /translation="LRDALGLDDLDPDASLYDHGADSLTLIDLIAEVDERFGVDIELSR
                     LSHRVSLNEVLTHL"
     aSDomain        12319..12984
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_detG_Thioesterase.1"
                     /evalue="5.60E-23"
                     /label="detG_Thioesterase.1"
                     /locus_tag="detG"
                     /protein_end="3030"
                     /protein_start="2808"
                     /score="74.4"
                     /tool="antismash"
                     /translation="VCLVHPVGGDIQAYRALVSALDDRLTVCLIADPALRAAEPPVWSL
                     AERARRYHAALQARFPHGTWRWRLAGWSFGAWVAQAMAADAEAAGRPAAGLYLLDPPPP
                     DAGAHFRAYDDTRLEAVFAHELNQGGGAARASAGATAYAERLARCCRANIAGMAEHEPP
                     ALAATPTWLWLATRPVAGLPALGAPDRQQRLWQERLPALQECHPLDTTHYDIVRAPRVL
                     "
     CDS_motif       12517..12570
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_detG_0017"
                     /evalue="1.00E-07"
                     /label="NRPS-te1"
                     /locus_tag="detG"
                     /protein_end="2892"
                     /protein_start="2874"
                     /score="24.4"
                     /tool="antismash"
                     /translation="WRLAGWSFGAWVAQAMAA"
     CDS             13069..14124
                     /codon_start=1
                     /note="FIG01024442"
                     /product="hypothetical protein"
                     /protein_id="DAC80530.1"
                     /transl_table=11
                     /translation="MNPYQALPPRSFWRTAVAEPDPRDITGLWTPAFALGQDDVVLTAG
                     SCFARHIGRALLERGMNWRDAEPAPPGLTPAEREARQYGAFSFRTGNIYTAATLRQWLS
                     WAFGESAPPQEVWQDGDRFFDPYRPSVEPEGFASPDEVARAREHTLAAIRGAVTEADCL
                     IFTLGLTEAWLDRVDGTVLPVCPGTVRGTYDAERHAFHNFTFAEVHRDLAGAVELARAV
                     NPGLRVLLTVSPVPLTATATGGHALTATTYSKSVLRAVAGQLAQELDHVDYFPSYEIVT
                     GAPFKAGFFEPNLRTVTPEGVDFVMGRFFEALSQAPSAAEQRPPAARPTTPTSGEDFWC
                     DDAVLDYYNSH"
     CDS             14171..14794
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAC80531.1"
                     /transl_table=11
                     /translation="MIGRAAKAAGIPFSGGPVGSGRDFNAEFFDRRGDDVVFRKADTDA
                     LYRGFLKELGIGGLDELTVPLVCTFGFSAHFVATTANWDVYRVGGGFVPGFLESRLFDD
                     LVRATVRDALAFYGHARDLGLRVVSAMPPQRVPGMSDPVVFMAAQDVMRRALLELGVEV
                     VDLRARVTDAAGVQRPEFSEATDAIHGSLGFGRLILAELLALGL"
     gene            14887..15759
                     /gene="tauD"
     CDS             14887..15759
                     /EC_number="1.14.11.17"
                     /codon_start=1
                     /db_xref="GO:0000908"
                     /gene="tauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121:dioxygenase, TauD/TfdA (Score: 281.3; E-value:
                     1.2e-85)"
                     /gene_kind="biosynthetic-additional"
                     /product="alpha-ketoglutarate-dependent taurine
                     dioxygenase"
                     /protein_id="DAC80532.1"
                     /transl_table=11
                     /translation="MEQFALDAIEAITTRPPEVYDHITVDALTPVIGAEVSGLDLSKEL
                     TDEQAAEVKRAFLRHHVLVFRDQVIDGEQHKRFARHFGELHPVALAPEGSDPHILEISA
                     DAESRNVAGHGWHADGTADLKPSLGSMLYVTRTPEIGSGGDTMFSNMHLAYEMLSPAMK
                     ALLDPMTAVHNGLLAWEGATPPPEYDVPVNVHPVVARHPDTGRKLLFVNGIYVSHIEQL
                     SKGESRAIIDMLVKHITNTALLSCRVRWTPNTLVFWDNRCVQHHAIWDYFPHSRYAQRV
                     AIAGHRPTA"
ORIGIN
        1 gtcctccgca cagcaacggc tgtggttcct gtcgcaaatg ccgggcgcga gcgaggcgta
       61 ccacctgccc acggcggtgg agctgcgggg cgccctggac cggacggcgc tgagccgggc
      121 cctggacgcg ctcgtcgccc gccacgaggt gctgcgcacc cgtctcgagg ccgtcgcggg
      181 cgcggccgtc cagcggatcg acccgcccgg cgccggcctg cccctcgcga ccgacgacct
      241 gaccggcctg cccgacgccg aggccgaggc cgaactcgcg cgcgtgcggc gggaggaggc
      301 cgcggccccg ttcgacccgg cgcgcgggcc cctgctccgc ggccgcctgg tggtcctcgg
      361 cgccgaccgg cacgtcctgc tgctcacggt gcaccacctc gtgtccgacg actggtccat
      421 ggacgtcctg acccgggagg tcggcgccct gtacgcggcc ttccgcgagg gcgcgcccga
      481 cccgctgccg ccgctgcccg cgcagtacgc cgactacgcc gcctggcagc ggcagtggct
      541 ggccgacccc tcgcccgacg gggccgcggc ccggcagagc gcctactggc ggcaggccct
      601 cgcggacgcc cccgcggtgc tccagctgcc caccgaccgg ccgcgcccgg ccgagcagga
      661 ctaccgcggc gggcgcgtcg agctcgcctt cgacgaggag ctgacggccg cgctcaagga
      721 cctcggcggg cgcgacggcg cgtccttgtc cacgacggtc ctcgccgcgt gggccctggt
      781 ggtcgcgcgc gccgcgggcc agtccgacgt ggtgatcggc acgcccaccg ccaaccgccg
      841 cggcgccgaa ctggaagggc tcatcggctg cttcgccaac accttggcgc tgcggatcga
      901 cgtgtccgac gacctgacgg tggccgggct gctcgaccgc gcccgcacgg caacgttgtc
      961 agcactgcgt caccaggacc tgccgttcga gcaggtcgtc gacctcgtca agccggtccg
     1021 cagcctcgcg cacacgccgc tgttccaggt gatgttcgac tggaacggca ccgagcgggc
     1081 cgcgtgggcg ctgccgggcc tggaggcgac cccgctcgcc ccgccccgcc aggtcgccga
     1141 gttcgacctg accctgtccc tggcggagga gggcggccgg ctcacgggcg cgctcggcta
     1201 cgccaccgcc ctgttcgacg ccgcgacggc cgagcggtac ggccgccagc tgcggcacgt
     1261 cctggagcag ctggccgcgg gtcccgacac gccggtcgcc gaggtgaccc tgctcgacga
     1321 ccgcgcccgc cgtcaggtgc tcgtggactt caacgacacc gcccgcgcgg gctcgcccgc
     1381 cggtctggtg gagcgcttcg aggcccaggt gcgggagcgg cccggccaga ccgccgtggt
     1441 ccacgggggc gacgcgctcg actacgccac gctcgaacgg cgtgccaacc ggctcgccca
     1501 cgcgctcatc gcccgcggca tcgggaccga ccgcgtcgtc ggcctgcaca cgcacctgtc
     1561 ggtggacctg ctcgtgggca tcctgggcgt cctgaaggcg ggcggcgcgt atctgccgct
     1621 cgaccccgcg ctgcccgcgg agcgccttgc gggcatggtg gcggacgccg acgccctgct
     1681 ggtcctgagc aacgacgccg cgccgccgga cgacgcctgg ctgccgctca ccgccgtgga
     1741 ggccgagggg gcgcgggacg acgcgcccgg ccgcggcttc cgcccggacg acctggcgta
     1801 cgtgatctac acctccggtt ccaccggccg ccccaagggc gtggccgcga cgcaccgggg
     1861 catcctcaac ctcctggact actggctggg gcagttcgac gcgacgccgg gccaggcatc
     1921 ggcgatgtgg ccgagcttcg ccttcgacgc ctcggtgcag gagctgctgc tcccgctcac
     1981 ttcgggcggg gtcctccagc tggtgcccaa ggaggtgcgg gacgaccccg aggccctcct
     2041 ggactggatg cgcgagcacc gcatcgtgga ggcgctgctt ccgcccgcct acgtgaagtg
     2101 gatctgcgag gctcccgagg agcgtctcgc gggcctgtcc ctgcgctaca tccacaccgg
     2161 tctggagccg ctgcccgagg acagcctgca ccgcatgacc caggtcctgc cggggctgca
     2221 catcctcaac ggctacggcc ccaccgagac cgccctgtac tgcaccgcgt acctcacgcc
     2281 ccagccgctg gagcgccagg ccccgatcgg cccgccggtg gccaacaccc gtacgtacgt
     2341 gctcgacgag cgcctcaggc cggtgccggt cggcgtggtg ggcgagctgt acatcgccgg
     2401 ggccggtatg gcgcgcggct atctgggccg cccggatctg accgccgagc ggttcgtggc
     2461 cgaccccttc gtgcccggcg cgcgcatgta ccgcagcggc gacctggtcc gctggctgcc
     2521 ggacggcaac ctcctgtacg ccgggcgccg cgaccaccag gtcaaggtgc gcggcttccg
     2581 catcgagctg ggcgagatcg aggcgacgct gctcgaccag cccggcgtgt ccgaggccgc
     2641 ggtcatcgcc gaccgcgacg gcgcgggcga gccgcagctg gtggccgccg tgggcgtggg
     2701 cgacgcggcg ccgcgcccgg ctgccgagtg gcgcgcggcc ctggcccagc gcctcccggc
     2761 ccatatgatc ccgggcatct tcgtcgaggt gccgcgcctt ccgcagaccc agaacggcaa
     2821 gctcgaccgg gcggcgctcc tggagcgggc ccgcgccgac cggcccgccc aggtcaacct
     2881 ggcgagcccg cgcgaccaca tcgagctgac gctctatcag atatggcgga gcctgctgct
     2941 ccagccggac atcggcatcc gcgacagctt cttcgacatc ggcggcacct cgatctccgc
     3001 catcaagctg gtgcacgcca tccgcgaggc cttcggcgag accctcctgg tccgcgaggt
     3061 catgctgcac ccgaccatcg aggagctggg cgggcggctg cgccgcggcg cctccggagc
     3121 gccgcccagc aacctcctgc agttccgccc gggcgacggc gacgcgcacg tcgtctgcgt
     3181 ccacccggcg ggcggcaccg cattctgcta cctctcgctc gccaaggcgc tgccggagaa
     3241 cgtcggcgtc cacggcatcc agtcccccgg cgtgaacccc ggagagacct tcctgcccac
     3301 ggtcgaggcc atggccgagg cctatctgaa gctcatcgag ccgctctccg gcgggccgct
     3361 gatcctcacc ggactctcct acggcggtct cgtcgtccac gagatgggcc ggctgctggc
     3421 cgcagcgggc caccgggacg tcagcgtggt cctgctcgac gcccagggcg ccggcaacgc
     3481 ggagcagcgc gccaacatca ccaccgtcga catggccgag ttccgcgaca agctggtgaa
     3541 gttcaacggc atgtacccgg gcatcgacga ccggcagatc gaacagtact tccacatcta
     3601 caaccacaac cgcaccaccg cggtcgccta cgacccgcgg ccgaccgcgg cccgcaccgt
     3661 cttcctccag gcggtcgagg gcgcgacgga ccaattcctc gcggacgtac gggacttctg
     3721 gcgggaccgc gccgacggcg acttcgaggt ggagtcgatc gcctgcgacc actggggcat
     3781 gctggagtcc gccgagatcc tccgggtggc cgcgcggatc gagtcggaac tggcccggtt
     3841 cgccgggtcc gccaagccgc ggctcgccga gtccgccccc gcacgggagg cggaatgacc
     3901 atcgccgcac cggtgccgtc ctcggccccc acgctcgccc gggcggtgct cgaccgggcc
     3961 cgccgccacc ccgacgccgt cgcggtcgtc gaaggggagc ggtcgcgcac ctacggagag
     4021 ctcgacaccg cgagcgccgc cgtcgccgcc gccctgcgcc accacggcgt acgcccgggc
     4081 caggcggtcg cggtcggtct gccgcgctcc tgggagctgg tctgcgccat gctcggcgcc
     4141 ctgcgcgcgg gcgcggtggt cgtgccgctc gacgcccaga gcccggccga ccggcgcgcc
     4201 cacatcctga ccgactcggc gagcgtggcg gtgatccacg gtgccgcggc gcccgacgcg
     4261 ctacccgacg gcgtgcggcc gctgccggtg gccgcgctgc tcgacggcgg ccacggcgcg
     4321 tcgcacgagc tcgcgcccgc cgcgccggtc tcgttcgtct tctacacctc cggcaccacc
     4381 gggcagccca agggcgtcga ggtgcgggac gcgggcgtcc tgcgcctggc ccggcccggc
     4441 tacgtcgaga cgcacgaggg cgccggcttc gcctgcatgt ccaaccccgc cttcgacgcg
     4501 atcagcttcg aggtgtgggt gccgctgctc accggcggcc gctgcgtgct cctcgacgac
     4561 gggacggtcc aggaccccga ggtcctcgcg gccgccctgg agcggctgcg cgtcgacatc
     4621 gtgttcatca cggtggcgct gttcaacgcc gtcgtggaca aggtgccgca ctgcttctcc
     4681 tccgtcggcc aggtcctcac cggcggtgag cagctcaacg cccgcctcat ccgccgctgg
     4741 taccgcgaca acgccgacag cggcacgcgg ctgcacaacg tgtacggccc caccgaggcc
     4801 accacgttcg cgctgtgcca ccccattccg cgcgacttcg acggcgacgt ggtgccgatc
     4861 gggcgcgccc tcccgggcac cgagacgctc ctggtggcgg ccgacggcag ccgggcggcc
     4921 gcgcccggcg aggtggccga gctgtatctg gcgggcgagg cgctcgccgc gggctaccgc
     4981 aacctccccg aggagaccga gcgccgcttc gtcacgctgc cctggcacga ggacggctcc
     5041 cggcgccact accgcaccgg cgacctggtg cgcctggacg ccgcgggcga cgtggcgtac
     5101 gtggagcgcg ccgaccgcca ggtcaaggtc cgcggcttcc gcgtcgaacc gggcgagctg
     5161 gagcggcaga tcgtggcgca cccggcggtg cgccaggcct acgtgtgcac ccgccgcgac
     5221 gcgagcggcg tcaacgaact gctcgcctat ctcgtcctcg gcgccgacct cgcgtacgac
     5281 gacttcgacg cgcacctggc ggcgagcctg cccgcgtaca tgcggccgca ccgcgcctat
     5341 ctcatcgacg cgctgccgct caacgcgaac ggcaaggtgg acagggccgc gctgctgcgg
     5401 cgccccgacg cgccctggcg acgggccgac gaacccggtg cggccgaggc cgtcaccgac
     5461 cggcagcgcg aggtgctcga tctggcgggc gaggtgctcg gcctcaccgg gctccgcctc
     5521 gccgatcgct ggatcgcctg cggcggcgac tccctgaagg cactgcgcct gcgcttcgag
     5581 gcgcgccgcc gctggggctg cgaactgccc caggccctgg tcctgcacgg ggacttcgcc
     5641 cagctggccg ccgccgtcga ggcgggccgc gacgcggacg gcaccggcgg ctcgccctac
     5701 ccggcggcgc ccgccccggc cggtgcgcgc tccgcccccg cgacctccga gcagcagcgg
     5761 ctctggctcc tgcaccagcg cgaccccgcg tcacgggcgt accacgtgcc gatggtcttc
     5821 cgcgtggacg gggacgtgga caccggcgcg ctgcggcgcg ccctgtcccg cctcgtcgag
     5881 cggcacccgg cgctgcgcac cgccttcgag gccacgcccg agggggtgcg gcaggtggtg
     5941 gccgagccgt acgacccgtg gacggagccg gacgcgcagg cgctgcgcga cgaggacggc
     6001 cgccgcgcct tcaccgcgcg gttcctcgcc gcccccttcg acctggcgcg gccccggctg
     6061 ttccgcgcct gctggctgcc caggaccggc ggcggcgaac tgctgctgct cctgcaccac
     6121 atcgcggtcg acggctggtc cctcaacgtg ctcttccgcg agctttcggc cgactacgca
     6181 cacgacggcg aagcaccgga gcagcagacg cggcccgcgc cgaccccgct cgactacgcc
     6241 acctggcaga gcgagtggtt ctcccgcgag gcctaccgga cgcagcgcgc cgaactgcgc
     6301 gcgcactacg ccgagtcggc cgacgccgcc ccggacagcg cgccgctgga gccggtccgt
     6361 cccgacgaac gcgcggggct gctgcacacc acgctcgacg cggaccgccg cgccgcgctc
     6421 gaccggctct gcgccgagct cggcctcacc cgcttccagc tcctcctcgg ggtgtacgcc
     6481 tggagcctgt acggggtgac gggccgcgcc cggccccgga tcgcgggccc cgtcgccaac
     6541 cggccggtgc aggacttcga ggccagcgtc ggcatgttcg ccaacaccgt cctgctgccc
     6601 ctcgacctgg cgccgggcga gcggctccgc acccagctgc ggcagcacgg cgccgcggcg
     6661 cgcgccgtcc tcgaccggca ggacgtggcc ctcgccgacg ccctggcgga ccggggagcg
     6721 ggcgcgggcg gcgccccgtt cgacttcctg ttcgtcctgg agaacaccga cttcgacgcg
     6781 ttcgccctgc ccggctgcgc gacccgcccc gagtggccgg tcccggaccg ggcgaagtgc
     6841 ccgctgacgc tgtcggtgat cgagcgcggc accggcttcg actgcctgtg ggagtacgac
     6901 gccgcgcact tcgacaccgc gcagctggcg gccctcgacg cgctgttccg acaggccctg
     6961 gaccagctgg ccgacggctc cgacaccacc ctggccgagc tggtcgcgcc ctaccggcgc
     7021 gccctgcccg agctcggccg ctccaccgcg gagccgctgc cgttcaccac cgtcgccgag
     7081 ggcttcgccc ggcaggcgcg gcgcaccccc gacgcaccgg cgctcgccgc cggggaccgc
     7141 accgtcacgt acgccgaact cgacgcgcac gccgccgccc tcgcggccga gctgagcgag
     7201 cggcacccgg tggtgccggg cagcccgtgc cacgtcgcgc tgtacttcca gccgtccgtc
     7261 gagcacgtgg tggcgctcct cgcgctcgcc cggctcaacc tgaccgcggt gccgctcgac
     7321 ccgacgtacc cgcccgggct gctgcggcag atcctggagc aggtggagcc gctgtgcgtg
     7381 ctcgtcacgc ccggcgacga ggcggccctg gccgccctcg ctccggagga cctgccgcgc
     7441 cacgtggtca cggcggccgc ggccgccgtg gaaccggtgg agcagctccc gccgcacgcc
     7501 ggggcgcggc cgctctacac gctgttcacc tcgggctcca ccggcacgcc caagggcgtc
     7561 caggtgcccg acctgacgat gtgcaacctg ctccagtggc agcgcacgtc cggcggcctc
     7621 acggcacccg ccgccaccca gcagttctcc atgctgtcgt tcgacgtctc cttccaggag
     7681 atctacagca cgctgtgcgg cggcggcacg ctgcacctcg tccggcccgg ttggcgccag
     7741 gacgcgcccg cgctcctcga ccagctcgat tccgcgggga tcgaacggct cttcctgccg
     7801 tacgtggcgc tccaggtcct cgccgagcac gcggtgcggc tcggccgcta ccccgcgcgg
     7861 ctgcgcgagg tgatcacggc gggcgagcag ctgctgtgca ccgacgcgat ccgcacctgg
     7921 ttcgcggggc tgcgcggggc acggctgttc aaccactacg ggccgagcga gacgcacgtc
     7981 gtgagcgccc tgtgcctgga gggcgacccg gcgggctggc cggagcgccc cgccatcggc
     8041 accgccgtga cgggcgcctg gctgcgggtg gtcgacgagg ccggccagac cgtgccgccg
     8101 ggctgccccg gccgactgct cgtcggcggt ccgatggtgg tgccctgcta cctcaacgcc
     8161 ccggccctca acgcggagcg cttcgtcgag ctgccggggc tcggcacctt ctaccgcagc
     8221 ggcgacgtgg cccgcttcga ccacgacggc ctcctgcact acctgggccg agacgaccag
     8281 cagatcaagc tgagcggcca ccggctcgaa ctgggccagg tcgaggcggc gctcctgcgc
     8341 cacccggacg tcgccaacgc ggtggtggcc cgggacgagg acgcccggct cgtggcgtgc
     8401 ctggagtgcc ccggccacgt cccgtccccg gaggacctgg cccgccatct ggcgccgctc
     8461 cttcccgcgt acgtacggat cgaccggttc cggcggctgg cgcggcttcc gctcacgccg
     8521 agcggcaagc tggaccgccg cgcggtgctg accgcgcccg gcgacgagct gcggccgcgg
     8581 ggcggggccg cgccggccct gtcggcgcgc gaggcccggc tcaccgagct gttcgaagcc
     8641 gtgctcggcc gtcccgtcgg gcccgagcag cgcttcttcg acgccggtgc gacgagtctc
     8701 gacctgatgc gcttccatct gcgctgcggc gccgagccgg gtctcgactt caccattccc
     8761 gacctgttcg agcacgtcac gatccgcagt ctggcccgct tcctggacca gggctccgcc
     8821 gccgcggcga cgagcgcgcc cgggtccgcg gcgcccgggc ccgagggcct ggccgacgag
     8881 ccgatcgccg tgatcggcat ggccgtgcgg ctgcccggcg ccgacgacct ggccgcgttc
     8941 tgggacctgg tgcggtccgg gggccgcggc atggagcact tcgacgccgc cgacgggctg
     9001 gtcggcgccc gcagccagat gtccgggctg ctcggcttcg acccggagca cttcggcatc
     9061 agccgccagg aggcgcggct gatggacccg cagcagcgcc acctcctgat gagttccgtc
     9121 caggccctgg cgcacgccgg gatcgcggac cccgcggggc ggcgcgtcgg catcgtcgcc
     9181 gggtgcggcg agaacacgta ccaccagtcc ctggtgcgcg aggccgaccc cgagcggctg
     9241 cccgacagct tccagatggc cctccaccac gacaaggact tcctcaccac caaggtcgcc
     9301 taccacctcg acctgacggg ccccgccttc accgtccagg cggcgtgcgc gagttcgctc
     9361 gtggccgtgc acgtggcggc cgggctgctg cgccagggcg acgccgacgt gatgctggcg
     9421 ggcggcgtgc tcgtcgacac gctcctgacg gacggctacc gctaccgccc gcagcacatc
     9481 ttctccaagg acggccactg ccggccgttc agcgacgacg ccagcggcac catcggcgcc
     9541 agcggcgtcg gcgtggtcgt gctcaagccg ctgcggctcg cgcggcgcga cggcgacacc
     9601 gtgtacgcgg tgatcaccgg ttcggcgctc aacaacgacg gctcgggcaa gctcagttac
     9661 agcgccccgt cgctgccggg ccagcgcgag gtgatccgca ccgcgctgcg ccgcagcggc
     9721 cgcaccagtg ccgacctcgg ctacgtcgag gcccacggca ccggcaccca gctcggcgac
     9781 ccggtcgagg tgggcgcgct gcgccaggcc ttcgacctgg ccggggccga ccggtgcgcg
     9841 ctgacgtcgg tgaagagcca gatcggccac ctgggcgccg ccgcgggcgt ggtcggcctg
     9901 gtgcgggccg cgctcgcggt gcaccacggg gtgatcccgc ccaacgtcga cttccaccag
     9961 ctcaatccga agctcggccc cgacatcgcg ccgttctacg tgccgacgcg gacgctcccc
    10021 tggcccgacg cgcggccccg ggtcgccgcg gtcagcagct tcggcatcgg cggcacgaac
    10081 gcgcacctgg tgctcgaagc cgccgacgcg ccggacacgg ccgccgaaca caccgccgtg
    10141 ccctgcctgt tgctctccag cagcagcgcg gagggcctgc gggccgacgc cgaccgcctc
    10201 gcctcctacc tggaggcgcg gcccgaggcg tacggcgagg tgctgcgcca cctccaggcg
    10261 ggccgcacgc cgcgccgctg gcgggccgcg gccgtgcacg ccgacgtgac cgcggcggtc
    10321 gcgtggctgc gcacggcgtc cggcgtcgag gtgaccccgg acgacgagcc ctgccccgcc
    10381 gccggccgca cggccgccga actcgccgac gcctggctgt ccggcaggac cgtgcactgg
    10441 cccgagggcc ccgcccaggc gccgtgggac ttcccgccgc cggtcttccg cctcgccacg
    10501 tacgacttcg agcgcgccgc ggaaccccgg gcggccgccg cggggccgca gcggctgccc
    10561 gaggccgact ggctgcacca gccgcagtgg acgcgcctca cccgcgccgc ccgtacggcc
    10621 gcgagcggta cgctccgcct cctcgtggtc atgaccgccg agccgctgcc gcccgaggcg
    10681 atgcgcgtct tcggcgcggc gtacgagcgg gtggtgcggg tcgaagcggc cggtgccttc
    10741 gcccgcctcg ccgacgacgt gtacgcggtg gaccccgccg acgccgactc gctgcgggag
    10801 ctgttcgacg ccctgggcga cgcggccggg gccgggatcg actggctgca cgcgctgccg
    10861 ctcaccgttg cgggaccggt cggcgagacg agcctggagc gcgcccggtg ggcctgtctg
    10921 gacactccgg ccgcgctcgt ccaggcggcc gggtcgctga gccttcggcc ctggtggctg
    10981 tcgtacggag cgcagcccgt taacggggac gtgcgccggc ccgagctggg gctcctcgcg
    11041 ggcgccggtg aggtcgtgcc gcaggagtcc ggcgtcgacg gccgctggct cgacctgccc
    11101 ggtgccgcgc ccgccgactg ggctgtcgcc gtcgtgggcc tgctccgcgg ggcggacgcc
    11161 gcgacggacc tgccgcggcg gctcgccctt cggcagggct actggtggcg gcaggcgctg
    11221 ctcccggtgc ccgcgcccgc gctggccgcg cccgccgcgc tgtccgtggc gccgggcggc
    11281 acctacgtga tcctgggcgg cacgggcggc atcggctgcg ccctcgcggc ctggctcctc
    11341 acgcacgccg actgccgcgt ggtcctgctg tcccgcagcg gacgcctgcc gtccgacctg
    11401 gcgcagtggg cggaccgcgt ggacttggtc gaggcggacc tggccacggc cgcggccgac
    11461 gacgtcctgg ccctgatcga gcggcacacc ggccgggtcg acggcgtggt gcacgccgcc
    11521 ggcgcggcgg gcggcggtct gatcgcccgg cgcgacggcg acgcgatgcg ctgggtgacg
    11581 gcggccaagc tgggcggcgc gctgctcgtg gagcgtctga tcgagcgcca ccggcccgag
    11641 ttcgccgtgt actgctcgtc catggcggcg ctgttcggcg gcatcggcca gttcgactac
    11701 gccgcctccg gcggcctcct cgacggcttc gcccggtacc ggtcggacgc ggacgaggcc
    11761 acgctgcgga tcggcatcga ctgggacatc tggagcgagg tcggcatggc gcgcgacgcg
    11821 ctgcgctcgg acgcccggca ccaggcccac ctcgcgttcg gcctcgcggt gaaggagggc
    11881 cagcggctct tcgagcgggc gctgcacctc cagctgccgc agctcctcgt ctccacgacg
    11941 gacatcgagc gagtgcgcga cttctacgcg cccccggccg acccggctgc ggctcccgcc
    12001 gtggggcaac ccacgacggc ggacgccggg cccgccgcag ccgacaccgg tgcgctcgcc
    12061 gggtggctcc gggacgcgct cggcctggac gacctcgacc cggacgcctc gctgtacgac
    12121 cacggtgccg actcgctgac gctgatcgac ctgatcgccg aggtggacga gcgcttcggc
    12181 gtcgacatcg agctgtcccg gctcagccac cgggtgagcc tcaacgaggt gctcacgcac
    12241 ctcggcgagg tcgcgcccgc caccaccgcc gagccggtca ccctggaggt ctggcaggag
    12301 ggcaccgggc acgaggtggt gtgcctggtg cacccggtcg ggggtgacat ccaggcgtac
    12361 cgcgcgctgg tgtcggccct cgacgaccgc ctcaccgtct gtctgatcgc cgaccccgcg
    12421 ctgcgtgcgg ccgagccgcc cgtctggtcc ctggccgagc gggcccgccg gtaccacgcc
    12481 gcgctccagg cgcgcttccc gcacggcacg tggcggtggc ggctcgcggg ctggtcgttc
    12541 ggcgcctggg tggcgcaggc catggcggcc gacgcggagg cggccgggcg cccggccgcc
    12601 gggctctatc tgctcgaccc gccgccgccg gacgccgggg cgcacttccg ggcgtacgac
    12661 gacacccgcc ttgaggcggt cttcgcccac gagctgaacc agggcggcgg cgcggcgcgg
    12721 gcgagcgcgg gggcgacggc ctacgcggag cgcctcgcgc gctgctgccg ggccaacatc
    12781 gcgggcatgg cggagcacga gccgcccgcg ctcgcggcca cgcccacctg gctgtggctc
    12841 gcgacgcggc cggtggccgg gctgcccgcg ctcggcgcgc ccgaccgcca acagcggctg
    12901 tggcaggagc ggttgcccgc cctccaggag tgccacccgc tcgacaccac gcactacgac
    12961 atcgtccggg cgcctcgggt gctgacggtg gccgacaccg tcaacgccac gtcggcgccg
    13021 gtccccgagg accgctgaca ccgcccgacg cacgatcgaa ggaccctcat gaacccctat
    13081 caagcactgc cgccgcgctc cttctggcgc accgccgtgg ccgagcccga cccgcgcgac
    13141 atcaccggcc tgtggacacc cgcgttcgcc ctcgggcagg acgacgtggt cctcaccgcg
    13201 gggtcgtgct tcgcccggca catcggccgc gccctcctgg agcgcggcat gaactggcgc
    13261 gacgccgaac cggccccgcc ggggctgacc ccggccgagc gggaggcccg ccagtacggg
    13321 gcgttctcgt tccgcaccgg caacatctac accgccgcca cgctgcggca gtggctgtcg
    13381 tgggcgttcg gcgagagcgc cccgccgcag gaggtgtggc aggacgggga ccgcttcttc
    13441 gacccgtacc gcccgtccgt cgagcccgag gggttcgcct cgccggacga ggtggcgagg
    13501 gcgcgggagc acaccctggc ggcgatccgg ggcgcggtca ccgaggcgga ctgcctcatc
    13561 ttcacgctcg gcctgacgga ggcgtggctg gaccgcgtcg acggcacggt cctcccggtc
    13621 tgcccgggca ccgtgcgcgg cacctacgac gccgagcggc acgcgttcca caacttcacc
    13681 ttcgccgagg tgcaccggga cctggccggc gccgtcgagc tcgcccgcgc ggtcaatccg
    13741 ggcctgcggg tgctcctgac cgtgtcgccg gtcccgctga cggcgaccgc gacgggcggc
    13801 cacgcgctca ccgccaccac gtactccaag tccgtgctgc gcgcggtggc cggacagctg
    13861 gcgcaggagc tcgaccacgt cgactacttc ccgtcgtacg agatcgtcac cggcgccccc
    13921 ttcaaggccg ggttcttcga gccgaacctg cgcacggtca cgccggaggg cgtcgacttc
    13981 gtcatgggcc ggttcttcga ggcgctctcc caggccccga gcgcggcgga gcagcggccg
    14041 cccgccgccc ggcccaccac cccgaccagc ggagaggact tctggtgcga tgacgccgta
    14101 ctcgactact acaactccca ctgacgccgc cgcggcccgg ttcctgctcc tcggcgactc
    14161 gcacgcgggg gtgatcggcc gcgcggccaa ggcggccggg atccccttca gcggcggacc
    14221 ggtgggctcc gggcgcgact tcaacgcgga gttcttcgac cggcgcggcg acgacgtcgt
    14281 cttccgcaag gccgacaccg acgcgctcta ccggggcttc ctgaaggagc tcggcatcgg
    14341 cgggctcgac gagctcaccg tgccgctggt gtgcacgttc ggcttcagcg cgcacttcgt
    14401 cgcgacgacg gcgaactggg acgtctaccg cgtcggcggc ggcttcgtgc cgggcttcct
    14461 ggagagccgc ctcttcgacg acctcgtccg cgccacggtc cgcgacgccc tcgcgttcta
    14521 cggccacgcc cgtgacctgg ggctccgcgt ggtctccgcg atgccgccgc agcgggtgcc
    14581 cggcatgtcc gacccggtgg tcttcatggc cgcccaggac gtcatgcgcc gcgcgctcct
    14641 ggaactcggc gtcgaggtgg tggacctgcg cgcccgcgtc acggacgcgg cgggcgtcca
    14701 gcgcccggag ttcagcgagg ccaccgacgc gatccacggc agtctcggct tcggccggct
    14761 gatcctggcc gagctgctcg ccctgggcct ctgaccggcc gtaccccgag gccgcagacc
    14821 ggccgcaccg cgcgggccgc caccaccggc cccacccact catccgatcc gcaggaggac
    14881 acgaccatgg agcagttcgc actcgacgcc atcgaggcca tcaccacccg gccgcccgag
    14941 gtctacgacc acatcacggt cgacgcgctg accccggtga tcggcgccga ggtgtccgga
    15001 ctcgacctgt ccaaggagct cacggacgag caggccgcgg aggtcaagcg ggccttcctc
    15061 cgccaccacg tgctcgtctt ccgcgaccag gtgatcgacg gcgagcagca caagcggttc
    15121 gcccggcact tcggcgagct gcacccggtg gcgctcgccc ccgagggctc cgacccgcac
    15181 atcctggaga tcagcgccga cgcggagtcg cggaacgtcg cggggcacgg ctggcacgcc
    15241 gacggcaccg ccgacctgaa gccgtcgctc ggctcgatgc tgtacgtcac gcgcaccccg
    15301 gagatcggca gcggcggcga caccatgttc tccaacatgc acctcgccta cgagatgctg
    15361 tcgcccgcca tgaaggcgct cctggacccg atgacggcag tccacaacgg cctgctcgcc
    15421 tgggagggcg ccacgccgcc gcccgagtac gacgtgccgg tgaacgtgca cccggtggtg
    15481 gcccgccacc ccgacacggg ccgcaagctg ctcttcgtca acggcatcta cgtctcgcac
    15541 atcgagcagc tctccaaggg cgagagccgg gcgatcatcg acatgctcgt caagcacatc
    15601 accaacaccg cgctgctgag ctgccgcgtc cgctggaccc cgaacacgct ggtgttctgg
    15661 gacaaccgct gtgtgcagca ccacgcgatc tgggactact tcccgcactc gcggtacgcg
    15721 cagcgcgtgg ccatcgcggg ccaccggccc acggcctgac gtacgcctga cgtacgaggg
//
