LOCUS       BGC0001881             43279 bp    DNA     linear   PLN 26-MAY-2019
DEFINITION  Pyricularia grisea strain NI980 phytotoxin pyrichalasin H5 gene
            cluster, complete sequence.
ACCESSION   BGC0001881
VERSION     BGC0001881
KEYWORDS    .
SOURCE      Pyricularia grisea (Magnaporthe grisea)
  ORGANISM  Pyricularia grisea
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Sordariomycetidae; Magnaporthales; Pyriculariaceae;
            Pyricularia.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 16:29:32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 43279
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..43279
                     /db_xref="taxon:148305"
                     /mol_type="genomic DNA"
                     /organism="Pyricularia grisea"
                     /strain="NI980"
     misc_feature    1..43279
                     /note="phytotoxin pyrichalasin H5 gene cluster"
     subregion       1..43279
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="NRPS, PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..43279
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(<245..>2095)
                     /gene="pyiA"
     mRNA            complement(join(<245..558,634..1088,1562..1611,
                     1685..>2095))
                     /gene="pyiA"
                     /product="PyiA"
     CDS             complement(join(245..558,634..1088,1562..1611,1685..2095))
                     /codon_start=1
                     /gene="pyiA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 149; E-value:
                     3.4e-45)"
                     /gene_kind="biosynthetic-additional"
                     /note="O-methyl transferase"
                     /product="PyiA"
                     /protein_id="QCS37511.1"
                     /transl_table=11
                     /translation="MASQDGTTELLSQSVNSTCIPGSTYHVDRGRASSASTPPTSPPLS
                     EVDYTPLLESTQEPRHEYTQLAHSLVKAMADYVGHLQEENLPMPSLEPAAQVHGGLKVQ
                     GGVAARDTVVKLAQKIVAMTMDPEMKLFISSLQFHFCSSLKVAIDLRVHELDECFRASS
                     RQADALALARYREPHEADTLGFGLAFNTTANFWEVLARDTEGKRSQRFNRAMRAVNINA
                     LEVIPRIYPFNRIGGNGLLVDVGGGLGQVARAIMATNQGSRLQRCIVQDVCAADDVLEE
                     VLESNRKLGVELQRHDFFDKQPVTGASIYFFRHIFHDWPDRACVKILKQIVQAMGRDSR
                     LLICDQVVDDEPSIPATLYDIDMWTLFGGKERNRSEWEALFRAADERLYIKKVWTTTEA
                     PTTILEVCLW"
     gap             2515..3354
                     /estimated_length=840
     gene            <3572..>5188
                     /gene="pyiE"
     mRNA            join(<3572..4390,4616..>5188)
                     /gene="pyiE"
                     /product="PyiE"
     CDS             join(3572..4390,4616..5188)
                     /codon_start=1
                     /gene="pyiE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /note="alpha-beta hydrolase fold protein"
                     /product="PyiE"
                     /protein_id="QCS37512.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.4e-12, bitscore:
                     35.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHKFFPRSGFFDFETVRILGTACYGGADVAEVLEAVGEIKSDDAA
                     SWEEAWRRQSWWAEALADQAREGGDREAARRAYLRASNYARASGYMYVSDLGAEGGNAP
                     PTQDPRALPVAEKVGRLFRKALALMEGEVRALSIPCGAQALPGLLYLPPPGKRIPGRDK
                     IPVLVFLGGADSCQEELYYLYPAAGPGLGYAVLTFDGPGQGIVLRKHGLRVRPDWEVVT
                     SSVLDYLEAYSAQHPGLELDMKAIAVSGASMGGYYALRSAVDRRVKACVSIDPFYDMWD
                     FGTAHVSPLFISAWTSGIISSGFVDKLMTVVSRLWFQMKWEIALTGTLFGLSSPSQILL
                     NMKNYTLSGKSDGSRANGKKSHSPTDGGGVESDSFLSEVRCPVFLSGAGKSLYLDVDSH
                     TRRCYDGLTGVAAKDKELWVPESEGQGSLQAKMGALALCNQKTFQFLDKVLGVQRVPLD
                     VSAHI"
     gene            complement(<5775..>7783)
                     /gene="pyiT"
     mRNA            complement(join(<5775..7093,7194..7404,7505..>7783))
                     /gene="pyiT"
                     /product="PyiT"
     CDS             complement(join(5775..7093,7194..7404,7505..7783))
                     /codon_start=1
                     /gene="pyiT"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 302.5; E-value:
                     6.7e-92)"
                     /gene_kind="transport"
                     /note="major facilitator superfamily transporter"
                     /product="PyiT"
                     /protein_id="QCS37513.1"
                     /transl_table=11
                     /translation="MEKAKDSLPTTGDPVPSQGTINPVDETGGSASDEKKAKKGCDFWF
                     TFSSLVLTAFLSALEGSVVSTALPTIARALEASENYVWVVNVYYLSKYETWLTYLLRFS
                     SAAFQPIYGQLADLWGRRWLTIGAVVIFTVGSGICGGATSIDMLIGGRAIQGLGSAGIN
                     MLVELILCDLLPLRERGQFFGIIFMFVILGSVIGPFLGGILVDRVSWRWVFYINIPFSG
                     VCVVLLFFFLHIKNAGTGNFIDKVKRIDFFGNFLLAASVGSCLFALTYGDTRYPFSDTR
                     IIVSLVLGLLGHVAFMFFEASPWCKEPVMPMVLFKNRTSAGAYIATFLQTLVSFWVLYF
                     LPLYFQSTQLVSATRSGVMLLPFSVVYALSSLAGGALTTKLGRFRNIHFASFALMTIGM
                     GTLTILNRSTSLAVIVVLEMIVALAIGVPTANLLTAIQAALPDELNALSTGTFAFLRSV
                     GTIWGVSIPAAIFNNRFDQLLPELSDPTAVRALQRGGAYQQATSEFVDSFPSDVRDVII
                     SIYERSLERVWQIGIVFAGVGFLVIFLERDLKLGTQKKTEDIEINDIPQTAADNSASRP
                     NTINDTASQAPILKQRRSTNQERETV"
     gene            complement(<9576..>11250)
                     /gene="pyiG"
     mRNA            complement(join(<9576..9982,10073..10753,10824..>11250))
                     /gene="pyiG"
                     /product="PyiG"
     CDS             complement(join(9576..9982,10073..10753,10824..11250))
                     /codon_start=1
                     /gene="pyiG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 119.5; E-value: 3.1e-36)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450"
                     /product="PyiG"
                     /protein_id="QCS37514.1"
                     /sec_met_domain="p450 (E-value: 7.4e-43, bitscore: 136.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNSAACIVLAITAVLGRMIYTHFYSNTCAAMKRALAHIPELHFE
                     EDDTPERYRTETRSLVRKGYERYLQYGIPFQMRNPVSELGNQVVLPVKYLEEVKRAPRS
                     LYSFEAFSEKVFLLKYIDAPRQTDALLYAVKLDINKNMDHILNGLWDETQVLLKETVPV
                     TGQITIPGGELACNIIARTMSYVLVGPSLCRNPEWTKIAIEATFALVAGTQGLRDRYSP
                     GWRWLARFQRSSEKLGEVREKAMELIKPLHEERMKALKDDSGQFRNFYDTIFWTMNKRK
                     VDRSLRAIVDQQLFLTLASIHTTAGTLQSILCDWLAHPEYHDEILAEINERLAAFKGAG
                     GKWTQQEVNEMKKLDSFMKESTRVNPVGCMTVQRYAQRTHTFSDGFVLPAGTIFQFPSD
                     AVHHDPKLFPDPEKFDGHRFLRLREKDANAYHYGYVSDTTLNWGAGTHACPGRFLATYV
                     LKFAFIALITQYDLSFPEGTGKPGYFYFDNSVRIDPTAKLDIKKSS"
     gene            complement(<11673..>12867)
                     /gene="pyiC"
     mRNA            complement(join(<11673..12228,12314..>12867))
                     /gene="pyiC"
                     /product="PyiC"
     CDS             complement(join(11673..12228,12314..12867))
                     /NRPS_PKS="Domain: PKS_ER (21-228). E-value: 3.8e-27.
                     Score: 87.1. Matches aSDomain:
                     nrpspksdomains_pyiC_PKS_ER.1"
                     /codon_start=1
                     /gene="pyiC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 180.1; E-value: 1e-54)"
                     /gene_kind="biosynthetic-additional"
                     /note="trans-acting enoyl reductase"
                     /product="PyiC"
                     /protein_id="QCS37515.1"
                     /sec_met_domain="ADH_N (E-value: 5.6e-09, bitscore: 25.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 7.8e-14, bitscore:
                     41.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTSNYGSLPTSRSAVVLGNDERLRIERHLPLPALRPNEVLVQVK
                     AVAINPCDYKMHQRFPCPGAVDGCDFAGVIVGVGPEVLKFGLGDRVCGAVHGSNPLRPE
                     SGSFTDYMTSESEFTLKIPAGLSFEQAVGMGVTGIGTLGMALFRTLQLPGSLDRPATKP
                     RTVLVHGGSSSVGTMAIQLLRLLGHVPIATCSPKNFALARRFGAEEVFDYNSPDCAAAI
                     KAYTKNTLSYILDPFTDAKSVDLCYKAMGRAGGRYCCLEMYPEYVLQRKSIKVGFVMGP
                     LLLGHRLALSQGYERDEDPEMRAFGVEWYKDVQKMLDRGLLKRHPIKLLGDSFEALIEG
                     VEMLQRKEVSGEKLVVALDSEQSKPVLTK"
     aSDomain        complement(join(12099..12228,12314..12804))
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiC_PKS_ER.1"
                     /evalue="3.80E-27"
                     /label="pyiC_PKS_ER.1"
                     /locus_tag="pyiC"
                     /protein_end="228"
                     /protein_start="21"
                     /score="87.1"
                     /tool="antismash"
                     /translation="ERLRIERHLPLPALRPNEVLVQVKAVAINPCDYKMHQRFPCPGAV
                     DGCDFAGVIVGVGPEVLKFGLGDRVCGAVHGSNPLRPESGSFTDYMTSESEFTLKIPAG
                     LSFEQAVGMGVTGIGTLGMALFRTLQLPGSLDRPATKPRTVLVHGGSSSVGTMAIQLLR
                     LLGHVPIATCSPKNFALARRFGAEEVFDYNSPDCAAAIKAYTKN"
     CDS_motif       complement(12322..12375)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiC_0001"
                     /evalue="7.30E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="pyiC"
                     /protein_end="182"
                     /protein_start="164"
                     /score="18.5"
                     /tool="antismash"
                     /translation="TVLVHGGSSSVGTMAIQL"
     gene            <13188..>14543
                     /gene="pyiF"
     mRNA            join(<13188..13984,14069..>14543)
                     /gene="pyiF"
                     /product="PyiF"
     CDS             join(13188..13984,14069..14543)
                     /codon_start=1
                     /gene="pyiF"
                     /product="PyiF"
                     /protein_id="QCS37516.1"
                     /transl_table=11
                     /translation="MLPSFIFVYSLLATATATSPDWPEPWPSHWREPGSDLFPNQQVHL
                     AVEEAGTGSGCRISNITSNEMAKGRTIVDFPLYAVGSLEEPKLQPLNSSGGEQWEFDGV
                     SEDGMQSFIFGFYRDPNYAILGTGNLRVSIEFGFEDRTRFSEVYYAQRSVVETCSLGTR
                     GLWVDKEAGWKFSFLVDAAMQEAIITLDSDTVKGRIIITSRAKPLAADGSTWPAENAST
                     VTIPYYYWSQPIPAGTVETNVEIKGKLIKWKGMGGHERFWSSFSWFTCMRSLQAVRAML
                     GPYVLSYFSFTSNLIPDLTHQSVVLFHDGAVVFRSTLGTPSETEDYATVTKTYGGATTG
                     TLKDKVTGFQLELVSPSKMRHYTFFVEHLNVGFEYILGEGVGGSGFSSQSRGGHVGLDQ
                     HEGVALTEALTFPKNSPLFRSNYV"
     gene            <16787..>18621
                     /gene="pyiD"
     mRNA            join(<16787..17080,17168..18065,18206..>18621)
                     /gene="pyiD"
                     /product="PyiD"
     CDS             join(16787..17080,17168..18065,18206..18621)
                     /codon_start=1
                     /gene="pyiD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 107; E-value: 1.9e-32)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450"
                     /product="PyiD"
                     /protein_id="QCS37517.1"
                     /sec_met_domain="p450 (E-value: 2.3e-37, bitscore: 118.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLSIKRKIIEPYLVIRQSLAPLKLSRWQLTKIMARTAFDGLPSG
                     TLIVLAALSLALLVAVLRIKSQERTRSKEIPGLPVVKRNHLHYLDIVREGRELYPGQPF
                     MAVNKRHSLVVFPPSCFNEIKRLPAHTASAKKFFNTTNYGDWSHVGEESPELIKSVIAD
                     LTRSLPARVHTRQDECRDVFDEVVGRRREWKEFPLLMTTFEIITQINACSFVGKTLATN
                     RSWVRSVMMLPVFIHVGVMLLDACPLIVRPFMAYLTFLPSIKNRWDLTRMLAPVLKKDL
                     EEYHEAKDKKEFLRPRAEGKVPFTGFLLSHYKSAQASLKQLISDYIHLSFDSTPNTAAV
                     MFHALCELAIHPEAVEALRQELDEVMVDGKLPPTHLQELRKMDSFLRECFRLHPFGIFT
                     LQRRVEQPVQLSVGPLLPPGTLMAVDGQAIDGSSELWPNPEKFDVYRFYNLRQKLGNEN
                     QYHFATTSPDSPGWGDGTQACPGRFFAVNTLKIAMAHFLRNYDIEIKPECLPLKTKPMP
                     SGFFSPDDRAIARIRART"
     gene            complement(<19597..>21432)
                     /gene="pyiR"
     mRNA            complement(<19597..>21432)
                     /gene="pyiR"
                     /product="PyiR"
     CDS             complement(19597..21432)
                     /codon_start=1
                     /gene="pyiR"
                     /note="Zn(2)C6 transcriptional regulator"
                     /product="PyiR"
                     /protein_id="QCS37518.1"
                     /transl_table=11
                     /translation="MHRFNPRRSACDRCRGHKLRCIRLDPGPNDTGALLPCKRCVKAGA
                     ECIHTANLSVKPPGDGHHSAHRATESPGHPAAFQQETRVSDRQLRESSLGISPTQPAPQ
                     RQTQRWSSSSGPHRPEDRESLPPWHMFATPMFSRQQLGFSKLPSHANGPPDDRTADGFE
                     VGSEAALAAPPGSERSPHRTSRAPSDGTTTFSLVDKVFDLDGRAVCPLSGSVLQENAGI
                     VTAAASTTVTSAQTHHMLPFSQVEPLTPSSYFNVPTCSTLTTGGAGSQSLRDQQMQQHQ
                     RHGSASGRSSAATQDSCLQLLSQLSSKFLMDFGKSSAGDWSKMANNNTNNHLSTTISNL
                     FDGLQIFLKTIECLRPATFLENSSSDSECSYSDLCDESEFVGSTGDNQMQVYPGAMAVD
                     HAHEGSSTENSAHRRGRGASPTADAAPQPLDMPMTLTILTCYTWLLKGYEVVLSEIYQM
                     LASQDRHQGLQTLPTIVQGVGIGGFKLEDHPDMQIEIVIHVGWQLLQRIEGLLGVRVVS
                     DEGRGGLGGSSRDESSTEGGDGGGAGSSASDERRILDPRAAAAVLDSWFTTTTRGGSGG
                     SGPGEGTGDSNGGRTVEIKGTIANIRKYLRSYGRN"
     gene            <22657..>24298
                     /gene="pyiB"
     mRNA            join(<22657..22902,23030..>24298)
                     /gene="pyiB"
                     /product="PyiB"
     CDS             join(22657..22902,23030..24298)
                     /codon_start=1
                     /gene="pyiB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transferase"
                     /gene_kind="biosynthetic-additional"
                     /note="O-acetyltransferase"
                     /product="PyiB"
                     /protein_id="QCS37519.1"
                     /sec_met_domain="Transferase (E-value: 1.9e-08, bitscore:
                     22.8, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFLSAGGLWASLFRARISPIVETDEVLPLTLIDNIAAARNAILS
                     EVIRFDQVLDVVKLRDGLTELIDKRGWRKLGGRLRLRPNGSLEIHVPREFTEERPAFRF
                     TSQAFDIAIEEHALGSQLPKLSDGPSLQPGSTSVDKFNLIPDKPEKLDDYVYSDRPILA
                     LHVTSFTNSCIVTLTWSHVVFGARGIKELIAAWSKVLHGEQNVPLLLGTHQDVLAGIGT
                     DGDKTAPFLLDPIKIKGLGLVRIIFGLLWEIWQHPTVETRALHLPKRFVSQLRQKCMEE
                     LGAFCREDPAPFISEGDVLEAWCSRFVAQARADEKPALVTNALDIKDRLTAPWSSRGEY
                     LQNTGCCTWTPVQPETLLRSPLGELAYVIRRSIQELATDDQLRAQLRIFRSLGHTKMLP
                     LFGNPNSRVISFSNWTKFNLFEVTNLGPAVISTSPSTRSDASTSPIGRPVYMHCEAAGD
                     SRMLRNCFNVTGKDWDGSYWITAHLYPEDWTKLEEYMRQTQQHISD"
     gene            <26197..>27596
                     /gene="pyiH"
     mRNA            join(<26197..26240,26339..26647,26736..26826,26952..27182,
                     27534..>27596)
                     /gene="pyiH"
                     /product="PyiH"
     CDS             join(26197..26240,26339..26647,26736..26826,26952..27182,
                     27534..27596)
                     /codon_start=1
                     /gene="pyiH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     121.9; E-value: 5.2e-37)"
                     /gene_kind="biosynthetic-additional"
                     /note="oxidoreductase"
                     /product="PyiH"
                     /protein_id="QCS37520.1"
                     /transl_table=11
                     /translation="MPNLQGRVAFVTGGNAGIGYHTVVFLAKAGAKVYFGARSASRAEA
                     AVERMYRENPGLLHGQVNWLQVDMASMKSVLAGCDKFRASESKLNILIHNAAHEGREPS
                     NMADSGVQITMQTNHLAVFAMTQELQPMLRTAAAEKDSDVRIVNVSSNAPSLTHSDEWR
                     PDFSDPHGGDIRYPAGQADGFLAAMKRYSVSKMAMNLLTAELQARYDREGVPIMVISVC
                     PGAVYFKPQVDTENVEEMMRQPT"
     gap             28848..28998
                     /estimated_length=151
     gene            <30235..>42858
                     /gene="pyiS"
     mRNA            join(<30235..30787,31078..37788,37851..39869,39944..>42858)
                     /gene="pyiS"
                     /product="PyiS"
     CDS             join(30235..30787,31078..37788,37851..39869,39944..42858)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (8-441). E-value:
                     1.2e-153. Score: 503.8. Matches aSDomain:
                     nrpspksdomains_pyiS_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (551-873). E-value: 1.8e-85.
                     Score: 278.8. Matches aSDomain:
                     nrpspksdomains_pyiS_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (950-1131). E-value: 1.7e-13.
                     Score: 43.1. Matches aSDomain:
                     nrpspksdomains_pyiS_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1419-1600). E-value: 1.3e-86.
                     Score: 282.3. Matches aSDomain: nrpspksdomains_pyiS_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2128-2302). E-value: 6.8e-52.
                     Score: 167.9. Matches aSDomain:
                     nrpspksdomains_pyiS_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2413-2487). E-value: 1.9e-08.
                     Score: 26.4. Matches aSDomain:
                     nrpspksdomains_pyiS_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2645-2939). E-value:
                     6.3e-63. Score: 204.4. Matches aSDomain:
                     nrpspksdomains_pyiS_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (3112-3516). E-value:
                     2.6e-71. Score: 232.2. Matches aSDomain:
                     nrpspksdomains_pyiS_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (3641-3710). E-value:
                     6.1e-12. Score: 37.8. Matches aSDomain:
                     nrpspksdomains_pyiS_PP-binding.1"
                     /NRPS_PKS="Domain: TD (3757-3979). E-value: 4.8e-51. Score:
                     165.2. Matches aSDomain: nrpspksdomains_pyiS_TD.1"
                     /codon_start=1
                     /gene="pyiS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 190.3; E-value:
                     9.9e-58)"
                     /gene_kind="biosynthetic"
                     /note="polyketide synthase; nonribosomal peptide
                     synthetase"
                     /product="PyiS"
                     /protein_id="QCS37521.1"
                     /sec_met_domain="itr_KS (E-value: 1.3e-164, bitscore:
                     537.4, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.5e-86, bitscore: 278.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6.4e-43, bitscore:
                     136.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4e-56, bitscore:
                     179.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.4e-73, bitscore:
                     234.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.2e-12, bitscore:
                     37.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.2e-38, bitscore:
                     122.1, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATFSEPVAIIGTGCRFPGQCNTPSKLWELLQTPKDLLKEIPEN
                     RFSTEAFYHPQNYHHGTCNVRHSYFLEEDLRGFDAQFFGINPVEAHSVDPQQRLLLETV
                     YESLEAAGLSMKEMQGSDTAVYVGVMSADFTDMIGRDPETFPTYFATGTARSILSNRLS
                     FFFDWRGPSMTIDTACSSSLIEPRTGANKPDCAEQVAGSNLILGSEQYIAESKLQMLSP
                     TGRSRMWDADADGYARGEGVAAIVLKKLSQAIADGDHIECIIRETGANQDGRTPGITMP
                     SATAQEALIRTTYKKAGLDISKRSDRPQFFEAHGTGTPAGDPIEARAVSNAFFGPRSHF
                     SPTSPDDTLFVGSIKTVVGHTEGTAGLAAVIKASLALQAGVVPPNMHLSKLNPKIEPFY
                     GNVQILSEARQWPKLAEGGVRRVSVNSFGFGGANCHAILEAYEPESTLDRRRYNKRTGK
                     CFTPFLFSAATENALAAQLDKYRAHVACGNASAPGDLKKLSLTLSNRRSALPWRAVVPA
                     SNSVERLIENLDQCNDFTNETSASSLGTRPRILGIFTGQGAQWPRMGAALIESSPAAAK
                     ILARLDESLRLLPIRDRPTWSLREKILEGAESSSVAMAFISQPVCAAVQIMLVDMLRAA
                     GIEFSGVLGHSSGEISAAYAAGYLSSEDAIRAAYYRGFHMKSLTQKKGAMIAVGTSYDD
                     AKELCDLPAFEGRVCVAASNSPFSVTLSGDADAIDEVKALMDEEKKFNRLLQVDRAYHS
                     HHMKACAAAYMASLQQCGVRTLTRTAASSRCQWVSSVYVRHSAELAAEGGLEAKYWASN
                     LTMPVMFTEALQKLLGDCKDGKAYDLAIEVGPHPALKGPAVQTMSEFLGGQSIPYTGVL
                     SRGKDDVESFSTTLGYIWRTLGEGAVDFLGYSRFMNEEQGEATITPLNGLPTYPWDHHR
                     KFWHESRLSRAYRFNKDPVNELLGRQILDGAPDQLRWRNVLKRNELDWLDGHQVQRQTV
                     FPFMGYVSACVEAAMKIRGDANVQSIELQNFKVGQAVAFNDDDSWIEILVVLDSIKESK
                     VKGTKTISAHFAFHSSSNNETVDMTTHAGCDVLVTYGDSISDLLPPPEIQADDEYFMLG
                     VESDRFYNVLDDIGLGYTGPFRALSGLQRKLGKATGRIKNPASSKLWRKPLLVHPAMLD
                     AGIQSIMLAYCYPGDTMMRSIYLPTGIRRLIINPEHCQTFAGEETDVLFQSSASVDDPQ
                     GLSGDVSIYAPGGLSCKAIQVEGLQTQPLFNPTEANDLNIFTELVWGVDRPDAKEIVNK
                     VDVQQLDGDLLFSLERVAYYYLRILDKSIPLSQRTGIDWHFGQLFAYVDHVLSRVERGT
                     NRFARKEWQHDTKEIILEILERYPDNIDLRLMRAVGENIAAVIRGEITMLEPMLQNNML
                     NDFYVVAHGMPRYTKYLASLASQIGHRYPHMHVLEIGAGTGGATKSFLGALDDKFSTYT
                     FTDISSGFFEKARSVFASYSAKMSFKMLNIEKDIGDQGFVEGSYDVVIASLVLHATRNL
                     GQTLRNVRRLLKPGGYLLLLEITENDQMRFGLLFGGLEGWWLGYDDGRALSPCINIEEW
                     EKYLKQTGFSGIDTLMPHDEILPVPLSVIVSQAVDERTELLKQPLQRLDPSTTLVPQLT
                     IIGSGALAEEVHRLLRPFCGRVNVIESLGHMGADQLPVGGAVICLADIQEPVFKSMDAD
                     KLRGFQTIFKQSGSALWVTQGTLNGNPYSRMVIGFGRTIVLEMLHLRLQFLDLDHEAPA
                     DPTAIVETFIRLHLAENWKNDGVKITPLLHSVEPEMHIDKEGRGFIPRFKLNKKQNDRY
                     NSGRRKIVKEVPLRQQPVELVPPKSEDASWLLAEGKNMPELKGAIDIDVFYTVTRAVEV
                     SGGTFLYAVLGARRDTKEVVLALSPTQASIIRVPQAFIIPAQDSVEYLQLFYTELLARA
                     VLRDVAAGTVVVVLRPTSMLSCAVDRLAADRGARVLHLADEPGSDWDYLHHKSSKVQVQ
                     DWVKSRLGTEAPPAVLLLDFGADQFLLAYLLECLPAEVTRAMVGAQSTSSKARMKLGQS
                     EQEIRSFLADVRYALLPAQQTHQSSKGRSSLKVFTLEHLTTNRAGSDVSVVSWPAGTST
                     IPVQVQPVNSKVTFSNDKTYWLVGLSGTLGLSLCEWMAQQGARYIVITSRNPNVDERWK
                     NKMEKLGIKVEIIANNICDRKSVRSVYSHICQTMPPIGGVAQGAMVLHDTAFSELDLER
                     INKVMQPKVNGSIYLEEIFHNTPLEFFVFFSSMACVTGNPGQSAYAAANMFMSGLAVQR
                     RKRGLNASVVHIGAIFGNGYVTRELSLEQQNFLRKVGNMWLSEQDFRQLFAEAVLAGQP
                     ENTGSPELSTGMMTIDNSEGTKENITWFDNPMFQHCIKESTDGKLGGQTAKGRAVPVKT
                     QLLEAINSAEVYEIIHDAFAAKLRSSLQLEDDRPIVDQTADTLGIDSLFAVDIRSWFIK
                     ELQLEIPVLKILGGATVGEILETAQQLLPMELLPKMDPNDKSPARKLKAQPDSSPDKAA
                     SAERSRAKAQTAIENDGDRKFAATRAESGAKKGETVSKKVEAVTRPSVQWQVPVEPSTA
                     VGDLDDKSFPGEDGVRLRAGSLDTTFTHKSSASSSASILDASEDQSADSVWSLDTVNNE
                     LAVSKKTPISFAQSRIWFLEKFLEDPASALNITLTIELDGSLDVDRFGKAVKLVGQRHE
                     ALRTRFVHGDDFDAPMQEVLVHSTLSLEQQDIASDAEADEVYRELQKYRYKLGEGENMR
                     IILLKKSNQLFHLVIGYHHINMDGVSLEVVLRELQMAYDSKRLPNFGTILQYPDFAALQ
                     QKEYKSGAWQDEIEFWRKEFDGRPPSVLPLLPMAKTRSRTALTSYSSHTAEFSLDQITL
                     AGIQSACESSKATPFQFHLATFYALLSRMVDAADICIGIGSANRHDTAMMQSVGIYLNL
                     LPIVLKSQPNETFASTLKRVRSKVMTAFAHSRVPFDVIVNELGASRATTHNPLFQVLVN
                     YRQGTATRRSFCGCQSEVRSFEQGQAAYDLGLDIIENPGGECKVIMTGQSTLFVPEDMD
                     MLKDMYQRLLLAFSRNQALRLAIPSLYDPEMVKHALRIGRGPSYTHKWPETLIHQIDDI
                     AKQKSHSLAIVDGSGTFLTYAHMSRRTNAIAASLRGIRRGSRVGVHLDPGADWVCSVLA
                     IMRRDAVYLPLDAVSGYSRLSAILQDSKPDLVLVDNSTEKDATAYFSPILAADQIFNID
                     TVSVTPPETLAIAAKRGSVAALMYTSGSTGVPKGIIMKHESFRNNIEIISEKLGYNNGH
                     TVTLQQSSFNFDMSLGQIFLALSTGGTLHVVPRHLRADPVAISSIIALHGITNTSATPS
                     EFISWVRYGSVEELRNSAWAAVHSGGEPVRDSLKAAFLTVNKPGLRLLDCYGPTEVTFC
                     SHISDVDYGAEETSMNKGLEVLPNYATYIVDSGMKPVPAGVPGEVLIGGAGVVAGYLHT
                     ELNTRGFAHDSFASDEFRKQGWEQLHRTGDFGRINKLNGRLLLEGRIADDTQVKLRGLR
                     IDLKEIEAAMVRAAKGDILDCIVSVAQSADVSDEYLVAYATARPDASNHRLEHLMHQLP
                     LPQYMKPATLVLLEKMPTNASGKIDRSAFKSIPLPKATEDNGMQPEVGQDLNDTESRLK
                     QLWEGVLPKHVFSQHKFTAASDFFNVGGSSMLLISLRAKIQDTFAVVVSLFQLFEASTL
                     GDMAALVDELSSGSAEKTAGPNSALDINWEDETAVSPALLGIPVEKKFFTNPEIVVLTG
                     STGFLGRAILTRLLNDGIVKEIHCFAVREEIPLFDSPKIIVHRGDLTLPGFGLSQKELA
                     SIFSKAHAVIHNGADVSFVKSYHSLKPANLEATKQLVDLCLPYQISFHYISTAAVVNLT
                     GEKSWEQRSVGRFPPPAGTDGYIATKWASERYLEKFNDQYGLPIWIHRPSSITGPGAPA
                     NDLMANVVEFSRSTAATLNTNSWSGWLDFISVDEAALQIVDEVYEDYSWPGHVKYLYES
                     GERVVALEDMKNVLEREVGSVFEVVDVEEWISRAEKQGFNPLLGEYLKRVANAPLVFPK
                     LIRHEGFF"
     aSDomain        join(30259..30787,31078..31847)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.20E-153"
                     /label="pyiS_PKS_KS.1"
                     /locus_tag="pyiS"
                     /protein_end="441"
                     /protein_start="8"
                     /score="503.8"
                     /tool="antismash"
                     /translation="VAIIGTGCRFPGQCNTPSKLWELLQTPKDLLKEIPENRFSTEAFY
                     HPQNYHHGTCNVRHSYFLEEDLRGFDAQFFGINPVEAHSVDPQQRLLLETVYESLEAAG
                     LSMKEMQGSDTAVYVGVMSADFTDMIGRDPETFPTYFATGTARSILSNRLSFFFDWRGP
                     SMTIDTACSSSLIEPRTGANKPDCAEQVAGSNLILGSEQYIAESKLQMLSPTGRSRMWD
                     ADADGYARGEGVAAIVLKKLSQAIADGDHIECIIRETGANQDGRTPGITMPSATAQEAL
                     IRTTYKKAGLDISKRSDRPQFFEAHGTGTPAGDPIEARAVSNAFFGPRSHFSPTSPDDT
                     LFVGSIKTVVGHTEGTAGLAAVIKASLALQAGVVPPNMHLSKLNPKIEPFYGNVQILSE
                     ARQWPKLAEGGVRRVSVNSFGFGGANCHAILEAY"
     aSModule        30259..38047
                     /complete
                     /domains="nrpspksdomains_pyiS_PKS_KS.1"
                     /domains="nrpspksdomains_pyiS_PKS_AT.1"
                     /domains="nrpspksdomains_pyiS_PKS_DH.1"
                     /domains="nrpspksdomains_pyiS_cMT.1"
                     /domains="nrpspksdomains_pyiS_PKS_KR.1"
                     /domains="nrpspksdomains_pyiS_PKS_PP.1"
                     /iterative
                     /locus_tags="pyiS"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       30742..30786
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0001"
                     /evalue="3.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="pyiS"
                     /protein_end="184"
                     /protein_start="169"
                     /score="19.0"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSLI"
     CDS_motif       31209..31247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0002"
                     /evalue="6.60E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="pyiS"
                     /protein_end="241"
                     /protein_start="228"
                     /score="12.8"
                     /tool="antismash"
                     /translation="WDADADGYARGEG"
     CDS_motif       31455..31499
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0003"
                     /evalue="2.40E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="pyiS"
                     /protein_end="325"
                     /protein_start="310"
                     /score="10.5"
                     /tool="antismash"
                     /translation="FEAHGTGTPAGDPIE"
     CDS_motif       31590..31658
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0004"
                     /evalue="6.20E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="pyiS"
                     /protein_end="378"
                     /protein_start="355"
                     /score="0.1"
                     /tool="antismash"
                     /translation="TVVGHTEGTAGLAAVIKASLALQ"
     CDS_motif       32178..32225
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0005"
                     /evalue="4.20E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="pyiS"
                     /protein_end="567"
                     /protein_start="551"
                     /score="13.0"
                     /tool="antismash"
                     /translation="IFTGQGAQWPRMGAAL"
     aSDomain        32178..33143
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_PKS_AT.1"
                     /evalue="1.80E-85"
                     /label="pyiS_PKS_AT.1"
                     /locus_tag="pyiS"
                     /protein_end="873"
                     /protein_start="551"
                     /score="278.8"
                     /tool="antismash"
                     /translation="IFTGQGAQWPRMGAALIESSPAAAKILARLDESLRLLPIRDRPTW
                     SLREKILEGAESSSVAMAFISQPVCAAVQIMLVDMLRAAGIEFSGVLGHSSGEISAAYA
                     AGYLSSEDAIRAAYYRGFHMKSLTQKKGAMIAVGTSYDDAKELCDLPAFEGRVCVAASN
                     SPFSVTLSGDADAIDEVKALMDEEKKFNRLLQVDRAYHSHHMKACAAAYMASLQQCGVR
                     TLTRTAASSRCQWVSSVYVRHSAELAAEGGLEAKYWASNLTMPVMFTEALQKLLGDCKD
                     GKAYDLAIEVGPHPALKGPAVQTMSEFLGGQSIPYTGVLSR"
     CDS_motif       32448..32543
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0006"
                     /evalue="4.30E-10"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="pyiS"
                     /protein_end="673"
                     /protein_start="641"
                     /score="31.6"
                     /tool="antismash"
                     /translation="VLGHSSGEISAAYAAGYLSSEDAIRAAYYRGF"
     aSDomain        33375..33917
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_PKS_DH.1"
                     /evalue="1.70E-13"
                     /label="pyiS_PKS_DH.1"
                     /locus_tag="pyiS"
                     /protein_end="1131"
                     /protein_start="950"
                     /score="43.1"
                     /tool="antismash"
                     /translation="ELLGRQILDGAPDQLRWRNVLKRNELDWLDGHQVQRQTVFPFMGY
                     VSACVEAAMKIRGDANVQSIELQNFKVGQAVAFNDDDSWIEILVVLDSIKESKVKGTKT
                     ISAHFAFHSSSNNETVDMTTHAGCDVLVTYGDSISDLLPPPEIQADDEYFMLGVESDRF
                     YNVLDDIGLGYTGPFRAL"
     CDS_motif       33456..33533
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0007"
                     /evalue="5.20E-05"
                     /label="PKSI-DH_m2"
                     /locus_tag="pyiS"
                     /protein_end="1003"
                     /protein_start="977"
                     /score="15.9"
                     /tool="antismash"
                     /translation="WLDGHQVQRQTVFPFMGYVSACVEAA"
     aSDomain        34782..35324
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="1.30E-86"
                     /label="pyiS_cMT.1"
                     /locus_tag="pyiS"
                     /protein_end="1600"
                     /protein_start="1419"
                     /score="282.3"
                     /tool="antismash"
                     /translation="ASLASQIGHRYPHMHVLEIGAGTGGATKSFLGALDDKFSTYTFTD
                     ISSGFFEKARSVFASYSAKMSFKMLNIEKDIGDQGFVEGSYDVVIASLVLHATRNLGQT
                     LRNVRRLLKPGGYLLLLEITENDQMRFGLLFGGLEGWWLGYDDGRALSPCINIEEWEKY
                     LKQTGFSGIDTLMPHDEI"
     CDS_motif       36909..37007
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0008"
                     /evalue="5.10E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="pyiS"
                     /protein_end="2161"
                     /protein_start="2128"
                     /score="48.0"
                     /tool="antismash"
                     /translation="TYWLVGLSGTLGLSLCEWMAQQGARYIVITSRN"
     aSDomain        36909..37430
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_PKS_KR.1"
                     /evalue="6.80E-52"
                     /label="pyiS_PKS_KR.1"
                     /locus_tag="pyiS"
                     /protein_end="2302"
                     /protein_start="2128"
                     /score="167.9"
                     /tool="antismash"
                     /translation="TYWLVGLSGTLGLSLCEWMAQQGARYIVITSRNPNVDERWKNKME
                     KLGIKVEIIANNICDRKSVRSVYSHICQTMPPIGGVAQGAMVLHDTAFSELDLERINKV
                     MQPKVNGSIYLEEIFHNTPLEFFVFFSSMACVTGNPGQSAYAAANMFMSGLAVQRRKRG
                     LNASVVHIGAI"
     CDS_motif       37278..37388
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0009"
                     /evalue="1.10E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="pyiS"
                     /protein_end="2288"
                     /protein_start="2251"
                     /score="63.0"
                     /tool="antismash"
                     /translation="LEFFVFFSSMACVTGNPGQSAYAAANMFMSGLAVQRR"
     aSDomain        join(37764..37788,37851..38047)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_PKS_PP.1"
                     /evalue="1.90E-08"
                     /label="pyiS_PKS_PP.1"
                     /locus_tag="pyiS"
                     /protein_end="2487"
                     /protein_start="2413"
                     /score="26.4"
                     /tool="antismash"
                     /translation="AEVYEIIHDAFAAKLRSSLQLEDDRPIVDQTADTLGIDSLFAVDI
                     RSWFIKELQLEIPVLKILGGATVGEILET"
     aSDomain        38522..39403
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.30E-63"
                     /label="pyiS_Condensation_LCL.1"
                     /locus_tag="pyiS"
                     /protein_end="2939"
                     /protein_start="2645"
                     /score="204.4"
                     /tool="antismash"
                     /translation="KKTPISFAQSRIWFLEKFLEDPASALNITLTIELDGSLDVDRFGK
                     AVKLVGQRHEALRTRFVHGDDFDAPMQEVLVHSTLSLEQQDIASDAEADEVYRELQKYR
                     YKLGEGENMRIILLKKSNQLFHLVIGYHHINMDGVSLEVVLRELQMAYDSKRLPNFGTI
                     LQYPDFAALQQKEYKSGAWQDEIEFWRKEFDGRPPSVLPLLPMAKTRSRTALTSYSSHT
                     AEFSLDQITLAGIQSACESSKATPFQFHLATFYALLSRMVDAADICIGIGSANRHDTAM
                     MQSVGIYLNLLPI"
     aSModule        38522..42597
                     /complete
                     /domains="nrpspksdomains_pyiS_Condensation_LCL.1"
                     /domains="nrpspksdomains_pyiS_AMP-binding.1"
                     /domains="nrpspksdomains_pyiS_PP-binding.1"
                     /domains="nrpspksdomains_pyiS_TD.1"
                     /final_module
                     /locus_tags="pyiS"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       38594..38707
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0010"
                     /evalue="1.60E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="pyiS"
                     /protein_end="2707"
                     /protein_start="2669"
                     /score="43.0"
                     /tool="antismash"
                     /translation="ALNITLTIELDGSLDVDRFGKAVKLVGQRHEALRTRFV"
     CDS_motif       38912..38977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0011"
                     /evalue="1.10E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="pyiS"
                     /protein_end="2797"
                     /protein_start="2775"
                     /score="21.2"
                     /tool="antismash"
                     /translation="YHHINMDGVSLEVVLRELQMAY"
     CDS_motif       39458..39574
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0012"
                     /evalue="5.40E-13"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="pyiS"
                     /protein_end="2996"
                     /protein_start="2957"
                     /score="41.2"
                     /tool="antismash"
                     /translation="SKVMTAFAHSRVPFDVIVNELGASRATTHNPLFQVLVNY"
     aSDomain        39997..41208
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_AMP-binding.1"
                     /evalue="2.60E-71"
                     /label="pyiS_AMP-binding.1"
                     /locus_tag="pyiS"
                     /protein_end="3516"
                     /protein_start="3112"
                     /score="232.2"
                     /tool="antismash"
                     /translation="IAKQKSHSLAIVDGSGTFLTYAHMSRRTNAIAASLRGIRRGSRVG
                     VHLDPGADWVCSVLAIMRRDAVYLPLDAVSGYSRLSAILQDSKPDLVLVDNSTEKDATA
                     YFSPILAADQIFNIDTVSVTPPETLAIAAKRGSVAALMYTSGSTGVPKGIIMKHESFRN
                     NIEIISEKLGYNNGHTVTLQQSSFNFDMSLGQIFLALSTGGTLHVVPRHLRADPVAISS
                     IIALHGITNTSATPSEFISWVRYGSVEELRNSAWAAVHSGGEPVRDSLKAAFLTVNKPG
                     LRLLDCYGPTEVTFCSHISDVDYGAEETSMNKGLEVLPNYATYIVDSGMKPVPAGVPGE
                     VLIGGAGVVAGYLHTELNTRGFAHDSFASDEFRKQGWEQLHRTGDFGRINKLNGRLLLE
                     GRIAD"
     CDS_motif       40411..40470
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0013"
                     /evalue="1.30E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="pyiS"
                     /protein_end="3270"
                     /protein_start="3250"
                     /score="21.0"
                     /tool="antismash"
                     /translation="AALMYTSGSTGVPKGIIMKH"
     CDS_motif       40996..41073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0014"
                     /evalue="2.70E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="pyiS"
                     /protein_end="3471"
                     /protein_start="3445"
                     /score="23.0"
                     /tool="antismash"
                     /translation="PAGVPGEVLIGGAGVVAGYLHTELNT"
     CDS_motif       41209..41259
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0015"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="pyiS"
                     /protein_end="3533"
                     /protein_start="3516"
                     /score="17.8"
                     /tool="antismash"
                     /translation="DTQVKLRGLRIDLKEIE"
     aSDomain        41584..41790
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_PP-binding.1"
                     /evalue="6.10E-12"
                     /label="pyiS_PP-binding.1"
                     /locus_tag="pyiS"
                     /protein_end="3710"
                     /protein_start="3641"
                     /score="37.8"
                     /tool="antismash"
                     /translation="RLKQLWEGVLPKHVFSQHKFTAASDFFNVGGSSMLLISLRAKIQD
                     TFAVVVSLFQLFEASTLGDMAALV"
     aSDomain        41932..42597
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_pyiS_TD.1"
                     /evalue="4.80E-51"
                     /label="pyiS_TD.1"
                     /locus_tag="pyiS"
                     /protein_end="3979"
                     /protein_start="3757"
                     /score="165.2"
                     /tool="antismash"
                     /translation="VVLTGSTGFLGRAILTRLLNDGIVKEIHCFAVREEIPLFDSPKII
                     VHRGDLTLPGFGLSQKELASIFSKAHAVIHNGADVSFVKSYHSLKPANLEATKQLVDLC
                     LPYQISFHYISTAAVVNLTGEKSWEQRSVGRFPPPAGTDGYIATKWASERYLEKFNDQY
                     GLPIWIHRPSSITGPGAPANDLMANVVEFSRSTAATLNTNSWSGWLDFISVDEAALQIV
                     "
     CDS_motif       41935..41985
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_pyiS_0016"
                     /evalue="1.60E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="pyiS"
                     /protein_end="3775"
                     /protein_start="3758"
                     /score="-1.7"
                     /tool="antismash"
                     /translation="VLTGSTGFLGRAILTRL"
ORIGIN
        1 tacagttgat agttgagaca ctcactcgac tctagcatct ttctttcctc actgcacttg
       61 ttactccccc acccctgaac agccagtccg cctttatcgc tcggttttct tcttcttctt
      121 gcttttccaa aattagcttg ttcaacgcct ttggcacttt tagtcttcca ttcgattttg
      181 gccaccccat taattccaat aacggaccac gtcgacggaa tctcaaacgt tgccacgccg
      241 tactttacca aagacaaact tccaaaatgg tcgttggggc ctcggtagtt gtccacacct
      301 tttttatgta cagcctttcg tctgcagccc ggaataaggc ttcccattca gaccgattcc
      361 tttccttacc accgaaaagg gtccacatat caatatcgta cagcgtggcc gggatagacg
      421 gctcgtcgtc cacgacctgg tcgcagatta gcaacctgct atccctgccc atggcttgga
      481 ctatctgctt caggatttta acacaggccc ggtccggcca atcgtggaag atgtgacgga
      541 aaaagtagat agaagcgcct ggagttttaa aacagccata tcgtgggtca gctactacgt
      601 gctttatatt aaaagcggga attcgaagct cacctgtcac cggctgctta tcgaaaaaat
      661 cgtgtctttg cagctccact cccaattttc gattcgactc caacacctct tccaacacgt
      721 cgtcggccgc acaaacatct tggacaatac acctttgcaa ccggctccct tggttcgtgg
      781 ccataatcgc ccgcgcgacc tggcctaggc cgccaccgac gtcgaccaat agcccgtttc
      841 ctccgatgcg gttaaaaggg tatatacgcg gaattacttc caaagcgtta atattcacag
      901 ccctcatcgc gcggttaaac cgttgcgaac gttttccctc tgtatcacgc gccaaaacct
      961 cccaaaagtt ggccgtcgta ttaaaggcca aaccgaaccc tagggtatcg gcttcgtggg
     1021 gctcgcggta tcgagcgagg gccaacgcgt cggcctggcg actcgaggcg cggaaacact
     1081 cgtccaatct acaaaaaggg ggacagcggg aaaagtgtgc tttagagtta gttttttttc
     1141 tctctttctt tttatcctgc catgggttta actttgcgga gggaaggagt aatgagatat
     1201 ttgcataagc tgtaaggagt gcaaaatgcg atggccccgg gaaccgactt accggtggcc
     1261 caaaagatca attatgtcgg gcgacttcat tatacaccag gaaatagtcg tgtgggcata
     1321 tgtaccgggt gtgggagaag aaaagacatg ttgagtaatt aggacccgca taattcggac
     1381 tatttacgag ggataaattt atataagtaa ataatctttt tatatgggtg ggttacagct
     1441 atttatacaa agggaatgcc gcggtaatag acgccaaatg tacataccca aaacagtctc
     1501 atctgcgcca acttttgtgg ctaattcgga acagtttatc gtcccttgac gaggaacata
     1561 ctcgtggact ctcaaatcga tagcaacttt gagcgacgag cagaaatgga actattccaa
     1621 gaaaagaaaa ccccgttttg ttaaccaggc tgccacggga aaaggtgtgt tataaaccac
     1681 ttacctgcag ggagctgatg aatagtttca tctctgggtc cattgtcatg gcgacgattt
     1741 tttgcgccag tttaacgaca gtatctcgtg ccgctacgcc accctgcact ttgaggccgc
     1801 cgtggacttg agcagctggt tcgaggctag gcataggaag attttcttcc tgcagatggc
     1861 ccacgtagtc cgccattgcc tttaccaggc tgtgagcaag ttgagtatat tcgtgtcggg
     1921 gttcctgggt tgattcaagt agcggcgtgt agtcaacctc tgacaggggc ggtgatgttg
     1981 gtggcgtcga ggctgagctc gcccgacctc tatccacatg ataggtgctg ccagggatgc
     2041 atgtgctgtt cacggactgg gacaggagct ccgtggtacc atcttgggag gccatagtta
     2101 atgcagacca ggtcaacgta ccgctatgga gatgcgggag cggcaatttt gacactttgt
     2161 gtttgttttg ataagatgag cacgaggctg atggagcaat ggagatgatc tatgtcgtct
     2221 cactgcctca ggtaccagga aaaccaagag ggaatgtgag tttctcaagt cgcaaagggg
     2281 gagttgtgag gaacccggtg acagttgggg gttgagtata tcttccctgt tgtgtatatc
     2341 cacttatagc cggactactg agatgcgatt agtttaaatt aactaggcta tccccgatcg
     2401 gtacattcat tcagggggtg tactacgtga cccgctccga accacatcgt tacttcaact
     2461 ccgacacgcc gaatcttttg catatctcac atattaaact gtaccaaaaa aaaannnnnn
     2521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnaaaaaa
     3361 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaacatg atggtgtggt ggatttcctc
     3421 ctcagtgcac actgtaggtt agcaaaaagg tattttaccg ccatcaactt tacgaaaacg
     3481 ggcatcggaa aaataaatcc ctcacaccgc ttgtgtctca ccattgaagc tgtcttcccc
     3541 ccctattcct ctcgccttca gacccgtcaa gatgcataag ttcttcccgc gcagcggctt
     3601 cttcgacttc gaaacggtcc gcatcctggg cacggcgtgc tacggcggtg ctgacgtggc
     3661 cgaggtgctc gaggccgtgg gcgagatcaa gtccgacgac gcggcatcct gggaggaggc
     3721 ttggcgcagg cagtcgtggt gggccgaggc gctcgccgac caggcgcgcg agggcggcga
     3781 ccgcgaggcc gcgcggaggg cctacttgcg cgcctccaac tacgcccgcg ccagcggcta
     3841 catgtacgtg tcggacctgg gcgccgaggg tggcaacgcg cccccgacgc aggacccgcg
     3901 tgcgctgccc gtggccgaga aggtcggcag gctgttccgc aaggccctgg cactgatgga
     3961 gggcgaggtg cgcgcgctgt cgattccgtg cggcgcgcag gccctccccg gactgctgta
     4021 cctgcctccg cccggaaaac gcatcccggg gcgcgacaag atccccgtcc tcgtcttcct
     4081 gggcggtgcc gattcgtgcc aggaggagct gtactacctc taccctgctg cgggaccggg
     4141 gctgggatat gccgtgctca cctttgacgg gccgggccag ggcatcgtgc tgaggaagca
     4201 cgggctgcgg gtgcgtcccg actgggaggt tgttaccagt tctgttctcg actatctcga
     4261 ggcatacagt gcgcagcacc ccggcttgga gctcgacatg aaggccattg ccgtatccgg
     4321 tgcctccatg ggtggttact atgcgctgcg atctgcggtc gaccggaggg tgaaagcttg
     4381 tgtttccatt gtaggtttcc tttttccccc ctcaccctcc caattcccta ctctttttgt
     4441 gctcttgttg gttcaagaaa aaacaacgaa aaacatctgg ctttctttca atttcgccac
     4501 cagtttaatt tgcaatattg gactttggat ttgaatcgat gtgcagtaat cgtaactatg
     4561 aattcatttg gcaaactact ccatctgact gcaagagaaa aaaaaacacc tacaggaccc
     4621 tttttacgac atgtgggact ttggcaccgc ccacgtatcc ccgctcttca tctcggcctg
     4681 gacttcgggc atcatcagct ccggcttcgt agacaagctc atgaccgtcg tgtcccggct
     4741 ctggtttcag atgaagtggg aaatagcctt gaccggaacc ttgtttggcc tgtcatcgcc
     4801 gtcccagata ctgctcaata tgaagaacta taccctgagc ggaaagagcg acggcagccg
     4861 tgccaacggc aagaagagcc actcccccac ggacggcggc ggcgtggaaa gcgacagctt
     4921 cctttccgag gtgcgatgtc ccgtcttcct ctcgggtgcc ggcaagtcgc tctacctgga
     4981 cgtagacagc cacacgcggc gctgctacga cgggctcacg ggcgtggcag ccaaggacaa
     5041 ggagctctgg gtgcccgaga gcgagggcca gggcagcctg caggcaaaaa tgggcgcctt
     5101 ggccctgtgc aaccagaaga ccttccaatt cctggacaag gttctgggcg tgcagagggt
     5161 gccgctggat gtttcagcac acatttaggc agacttgaaa agaaaatgcg tgtactggtc
     5221 tgtctgtcgt ttaaatttgc tgcattctat tcccccactt tcggtactgt ccattgtcaa
     5281 attggatcag cacattatga tagctctgtt tgttttatgt cctgcttgcc ttatcttgaa
     5341 gacttgtttt ttcggtagca aaaacagcat gctgccaact ttataattaa ttatcaaaat
     5401 cttctattgg cgaatgacat gcaaaatagc ggcattctac cgccttggtg tatgctgccg
     5461 gcagcgtaca aagagacgga tgagagaaga agaaagaagc gaaaaagaaa acggaaaaca
     5521 aaagaaaaaa aaaatatgag ccaaacctga agaagatgtt ccgcggcttg acagtgtaac
     5581 aaatcccgta gcatatatga gatctaaaga tccagactgt ccttttccta ccctttcctc
     5641 tattcctacc atgactacaa aacttttggt ggtccgagca ggtaccccca agcagtctac
     5701 ccgcctagtg ggcaaggaac caaagtagtt ccgttgttaa ttcgatgtgt ccccgacttt
     5761 tgttgcatct tgccctagac agtctctcgc tcttggtttg ttgaccgtcg ttgcttcaag
     5821 ataggggctt gagaagcagt atcgttaatt gtgtttgggc gggacgcaga attatcggcg
     5881 gctgtctggg ggatgtcgtt gatttctatg tcttccgtct ttttctgagt tcccagcttc
     5941 aaatctcttt ccaggaaaat gaccaggaac ccaacgccag caaagacgat tccgatctgc
     6001 cagactcgct ccagactccg ctcgtagata ctgatgatca catcacgcac atcagaaggg
     6061 aaagaatcca caaattcgct cgttgcctgt tggtatgccc ctccacgctg gagggccctc
     6121 acggcagtcg ggtcagagag ctcaggcaag agctgatcga agcggttgtt gaatatggct
     6181 gccgggatgc tgacacccca gatggtgccc acactcctca ggaacgcaaa ggtacctgtg
     6241 ctgagagcgt ttagctcgtc gggcaaggcg gcttggatcg ccgtcaacag gtttgctgtg
     6301 gggacaccaa tggctaaggc aacgatcatc tcgagcacaa cgatgacggc caaagatgta
     6361 ctcctattaa gtatcgtgag agtgcccatg ccgatggtca tgagggcgaa agaggcgaaa
     6421 tgaatgtttc ggaaacggcc cagtttcgtc gttagcgcac cccccgccag agatgagagg
     6481 gcgtagacga cggagaatgg caggagcatg acacctgatc tcgtggcgga gaccagctga
     6541 gtcgattgga aatagagcgg gaggaagtag aggacccaga aagagacaag ggtctggaga
     6601 aatgtcgcaa tgtacgcgcc tgcagacgtc ctatttttga acagcaccat cggcatgacg
     6661 ggctccttgc accatggcga ggcttcgaaa aacataaagg caacgtgacc cagaagtcct
     6721 aggacgaggc tcacaatgat gcgcgtgtcg gagaagggat accgtgtatc gccgtacgtg
     6781 agggcgaaca ggcaggagcc cactgacgcc gcgagcagaa agttgccgaa aaagtcaatc
     6841 ctcttcactt tgtcaatgaa gttgccggtc ccagcattct taatgtggag gaaaaagaac
     6901 aaaagtacca cacaaacgcc agagaagggt atgttgatat agaataccca tctccaggaa
     6961 acccgatcga cgagaatgcc acccagaaag gggcctatga cggatccgag gatcacgaac
     7021 ataaagatga tgccaaagaa ctggccgcgc tcccgcaaag gcaaaaggtc gcacaagatc
     7081 aattcgacga gcactagcaa ccacagattg tcagtcactc agctcgtttg gcttctttga
     7141 atgcatttga ctgaagaaag aaaacacaag caaaaccccc agtcacgact tactattgat
     7201 accagcagag cccaagcctt ggattgctcg gccgccgatg agcatgtcaa tcgatgtcgc
     7261 accaccgcat ataccactgc cgacggtaaa gatgacaaca gcgccgatgg taagccatcg
     7321 tcgaccccaa agatcagcca gctggccgta aatgggctgg aaggcagcac tagagaagcg
     7381 gagaagatag gtaagccagg tctcctgttg atgtatgcaa agtagagacc aggtcaaggc
     7441 aagctgagcc aagattgagg ccaaggtgag ggcaaagtga gggccaagga gccatttcgc
     7501 ctacatactt tgacaggtag taaacattga ctacccaaac gtagttttcg gaagcctcga
     7561 gggcacgcgc aatggtcggt agtgcagtgg atacgactga gccttccagt gcgctaagga
     7621 aggccgtaag aacaaggctg gagaaagtga accaaaaatc gcaacccttc tttgcctttt
     7681 tctcgtcaga cgctgaaccg cctgtttcgt ctacggggtt gatcgttcct tgggaaggaa
     7741 cggggtcacc agttgtcggc aacgaatcct ttgctttttc catgttggaa tggtgggatt
     7801 tgggcaaggg ttaggtttct gtttatctcc ttgtgttaag tttgagttgg ttgtcttcct
     7861 gatgctgttg tattgaatga aggacagtat gggggtattt tgggttttta ttttgtggct
     7921 agatgaggaa gggagaaaac aagagcagga gcgatggttc aagttgaagc aggacgcgaa
     7981 atgagcaggc agcggtggta acacaggatg ggggctgcac gtttgcagtt ctgtctcttg
     8041 tgtctaggta ggtacctacc tacctaggta ggtactgcct accatcccta ggtatcttac
     8101 ctaccaaggt acctacccag gtaattacct accttgcaaa tgcagcctgg catggatggg
     8161 gacccgcagt ggcatggtcg gtactcaaat ctaccctgta tctacacttg atttcttaag
     8221 ccctggtgtg ctctctccgt gtctttcgtc tccatcttgt gttgaaaaga ttcaaatctc
     8281 aattggctag gtagggaaaa atctcagccg tctaggtagg atgtgtattg gccaagttaa
     8341 aatgaatttg caatcaaaca cgaggaaggc caagcaaggc caaatgtgaa ctcaatccaa
     8401 aggcggacac caacacaatc cgcgagaacc actacggagt gcataaggta ctttgtagac
     8461 cagtttcaac attgggactg ccggtcgtag atacgatgga cttgattatt gcaggttatg
     8521 tttgcctgga caacagcatt agctagggac tggagcgttt gttttaacac cgcatttggg
     8581 tgctaacagt tacaggaccg gaaggttgac cacagtccac agcttgacag gtcgtagatt
     8641 cgggtccgaa tgtagagacg aattaatatc actagcaaag gtgtgtgtgc ttcgtattgt
     8701 ggatacgctc gaccgactac cacccctaaa aagttatctc ggtggtgtgg agccgccacc
     8761 cgacaaagtg gtgtgtttgc ggaacatatg taccgagcca ctagcattag cctgaaggac
     8821 gagggtcttg gttcgttttc agtgatgcat tttttttttt gtaacacagg gctgtgcaag
     8881 ctgccaagct gccaagagag tcgggggaga caggggttca ggtgatcttc gcattagtta
     8941 tatttgtata ttgtccccac atttctaatt ctctttctgc agccagtttc gataccgccc
     9001 ctttgacttg tttgggcttg aagagaccct ccgtcgttat gggactctac aaaccaacta
     9061 aaaggcttgt gggttcgatc ggaagaccaa cgaaacgagt gtatagcggc tcgtttgtta
     9121 gacgggctgg attgtgacga cggctatagc gcgcgtttat tcctgctggg cgtactcgat
     9181 accaagatag atgagcgctg gtacagggac ttaacattgt gaagaacggc tgatatagat
     9241 ctttgaagct atcgccaaac aataagagtc gttaaactag agttgatcac tacgtgaaac
     9301 gatgatgacc gaggggtatg tgaaaagagg cttttttgcg gccacaaccc atagcccctg
     9361 gtcatcccgg gtagcccggt cgaaaaagaa aaatctactt ccaagccact cccccccttt
     9421 tttttcctac caggttaaag taccgcctaa ttgctgaaaa ctcgatcaag tcagaagatc
     9481 acgcccttag gcaactagga aacttacact aggcaacagt tctaggcctc aattcatgtt
     9541 tcctgtttgc cgaggacatt tgagaatttc tgcaactaag agctcttctt tatatccagc
     9601 ttcgccgtcg ggtcaatcct caccgaattg tcaaaataaa aatatcccgg tttccccgtg
     9661 ccctccggga atgataggtc gtactgcgtg atcaatgcga tgaacgcaaa cttgaggaca
     9721 taagtggcga gaaagcgtcc cgggcaggcg tgcgtaccag cgccccagtt cagagtcgtg
     9781 tccgagacgt agccgtagtg atatgcattt gcgtcttttt cgcgaaggcg gaggaatcga
     9841 tgcccgtcga acttttcggg gtcgggaaag agcttcggat catgatggac ggcatccgag
     9901 ggaaattgga agatggtccc cgccggcagg acgaacccgt cgctaaaagt atgagtcctt
     9961 tgggcgtagc gctggactgt cactggtaat cacacaagat gcggtcagcc ttgggcatga
    10021 ttggtacatg attgtctaac tgcagtcggt gtttggcgtg gatgtccctt actgcaaccg
    10081 accgggttta cccgcgtgct ttccttcatg aaactatcca actttttcat ctcgttaact
    10141 tcctgctgag tccatttgcc tccggcaccc ttgaacgcag ctagcctctc gttgatctcg
    10201 gccaggatct cgtcatggta ctcgggatgg gcgagccagt cacacagtat ggactgcagg
    10261 gttccggcgg tggtgtggat ggatgccagg gttaagaaca gctgctggtc gacaattgcc
    10321 ctgagcgatc tatctacctt tctcttgttc atcgtccaga agatagtatc gtaaaagttt
    10381 cggaattggc cactgtcatc tttgagagcc ttcattcttt cttcgtgcaa cggcttgatc
    10441 agctccatgg ccttttcccg cacctctccc agcttttctg acgagcgttg aaaccgggcc
    10501 agccatctcc atccgggcga atatctgtcg cggaggccct gagtgcctgc gaccagggca
    10561 aacgtcgctt ctatcgcgat cttggtccac tcggggttcc ggcagagcga gggccccacg
    10621 aggacatagg acatggtgcg cgcgatgatg ttgcaggcaa gttcgccgcc gggaattgtg
    10681 atctggccgg taacgggaac cgtctccttt agaagcacct gggtctcatc ccagagcccg
    10741 tttaatatat gatctaggta gctccattgc gacgatcagc ttgagagccc ctccccaata
    10801 ctgtgccggg acgccttact cacccatgtt cttattgata tccagtttaa ccgcgtagag
    10861 gagagcatcc gtctggcgag gcgcgtcaat gtatttcagc agaaacactt tctcagagaa
    10921 ggcctcgaaa ctgtacagcg acctgggagc gcgcttgact tcctcgaggt atttcacagg
    10981 aagcacaacc tgattgccta gctcggacac cggattacgc atctggaatg ggatgccata
    11041 ctggaggtat ctttcgtacc cttttctcac gagggagcga gtctctgtcc tgtatcgctc
    11101 aggcgtgtca tcctcttcaa aatggagctc tggaatgtgc gctagagccc gtttcatcgc
    11161 agcacaggtg tttgaataga agtgggtgta gatcatacgg cccaagaccg ctgtgatggc
    11221 aagaacaata caggctgctg agttcaacat ttccacatgc agtcgcgaga tattgttggt
    11281 atttaaactg ggcttcgtaa aggtgttaag ttggttacag gggcagcgcc agtcaaccaa
    11341 tctgcgatga tcagatatgt atctatttat atgtaatcgg catgtcgggg gattcttttt
    11401 actgttcgcc aaatggagcc aatgttcggg cgcttacaac cttccttctg gggactggct
    11461 gcactagttt tttttttttt ttcttttttt taacaaaaag aaaaacaaaa aaaacaagag
    11521 ggatctggga gtgttaccag cccacaagat actgagcttg tttaaatttt agttgattgg
    11581 aagtggtctt tttgtgacga gaacccattt agccaaggag ttctcgagga cgagtggttt
    11641 cccaatttcg ctttgtttta attatatcat agctacttcg tcaaaactgg ctttgactgt
    11701 tcactgtcga gggcaaccac cagtttctcc cccgaaactt cttttctctg cagcatttca
    11761 accccctcaa tcaacgcctc gaaactgtcg cccaaaagtt tgatagggtg ccgtttcaac
    11821 agaccccggt caagcatctt ctgcacgtcc ttataccact ccacgccgaa tgcgcgcatt
    11881 tcgggatcct cgtccctttc gtagccctgg ctcagcgcca accggtggcc cagcaaaaga
    11941 gggcccatca cgaagcccac cttgatcgac ttgcgctgga gaacgtactc tggatacatc
    12001 tccaaacagc agtagcggcc tccagcgcgc cccatggcct tgtaacagag atccacactc
    12061 tttgcatcgg taaaagggtc caatatgtaa gacagtgtgt ttttggtata ggccttgatg
    12121 gctgcggcgc agtccggaga gttgtagtca aagacttcct ctgcgccgaa ccttcgggca
    12181 agtgcaaagt ttttgggaga acaagtagct atgggtacgt gtccgagtct tgtgtgcaac
    12241 tcccccagca tgttagccaa taataagatg cgttgcgcca ttcgtatgca ggagctgcgg
    12301 ggttgtcact cacagtcgca gaagctggat ggccatggtc cctactgagg agctaccacc
    12361 gtgcacgagc actgttcgcg gcttcgtcgc cggccggtcc aggctccccg gcagctgcaa
    12421 cgtcctgaac aacgccatgc ccaacgtccc tatacctgtc acgcccatcc ccacggcctg
    12481 ttcgaacgac aagccggctg ggattttaag cgtgaactcg gactcggacg tcatgtagtc
    12541 ggtgaaggag cccgactcgg gccgaagagg gttcgagccg tgaactgccc cacagaccct
    12601 gtcgccaagt ccgaacttga ggacctcagg cccgaccccg acaatcaccc ctgcaaaatc
    12661 gcaaccgtcg accgccccag gacaggggaa cctttggtgc atcttgtaat cgcatggatt
    12721 gatggccacg gccttgacct gcaccaggac ctcgttgggt cgcagtgcgg gcagcggcag
    12781 atggcgctcg atgcggaggc gctcatcatt gcccaagaca acggcggagc gtgatgttgg
    12841 cagcgagcca tagtttgatg tttgcatgct tgcagtgctt tgtcttgaca accacacgcc
    12901 aagaaaggtt tgcttaacga aggctcctcg cagcagtcac ccctatctct tctccttcgc
    12961 gaccatttta tacatctgtg gagccgcctt gcttgctgtc gcaactccga atgacttcgg
    13021 acgtgctatg tagacttaga atagagggcc gaaaacagca gccataaatt tgaagcctta
    13081 tatttgcttt cgcaacaaag attgtagaag tttcttcatt gtgtcagact caagcgtgaa
    13141 ccttgtacgc gtaaatttgt cctatttttt cttaccaaga acccacgatg ctgcccagct
    13201 tcatatttgt atacagcctg ctggccaccg caactgcgac cagccccgac tggccagagc
    13261 cttggccctc ccactggcgc gagccgggaa gcgatctgtt tcctaatcag caggttcacc
    13321 tagcagtcga ggaggctggc accggatcag gctgccgaat aagcaacatt acatcgaacg
    13381 agatggcaaa aggcaggact attgtggact ttccattgta tgccgtggga agcctggaag
    13441 agccaaaact ccaaccgctc aactcttcgg gcggagagca atgggaattt gatggcgttt
    13501 ccgaagatgg aatgcagtcc tttattttcg gattttacag agatcccaat tacgccatcc
    13561 tgggaactgg caacctgcgc gtgtctatag agtttggatt cgaggaccgc acaagatttt
    13621 ccgaagtgta ttacgcacag cgttccgtcg tcgaaacgtg ctctttggga acccgcggtt
    13681 tgtgggtaga caaggaggcc ggatggaaat tctctttcct tgtcgacgca gctatgcagg
    13741 aagccattat aacattggat tcggacaccg tcaaaggcag aatcattata acgtctcggg
    13801 cgaagccact cgcggcagat gggtccacgt ggccggctga gaacgcatcc acagtgacca
    13861 ttccttacta ctattggtcg caacctattc cagccgggac ggtcgaaaca aacgtggaaa
    13921 tcaagggtaa actcatcaag tggaaaggca tggggggcca tgagcggttt tggtcctcgt
    13981 tcaggtgaga tctttttggt gatattcggc caaatcacct tttgtaccaa tccagttgta
    14041 tctgacgctt acttccggtg atttatagtt ggtttacttg catgagaagc ctccaagcgg
    14101 tacgcgccat gttaggccct tatgtgctca gctacttttc cttcacctcc aacctcatcc
    14161 cggacctcac tcatcaatcc gtcgtgttgt tccacgacgg agctgtggtc ttccgaagca
    14221 cgctcgggac gccctcggag acagaggact acgctaccgt caccaaaacg tacggcgggg
    14281 ctaccacggg caccctgaag gacaaagtca ccggtttcca gctggagctg gtgtcgccgt
    14341 ctaagatgcg tcactataca ttcttcgtag agcacctcaa cgttgggttc gagtatatcc
    14401 tcggcgaggg cgtcggtggc agcggcttct cctctcaatc gaggggtggc cacgtcgggc
    14461 tggaccagca tgaaggggtc gcgcttaccg aggccttgac cttccccaag aactcacctc
    14521 tgttccgaag taactatgta tagactaagc tgaacactat ggcgcagggg taaatttgct
    14581 cccctatgct agggtttttc ccctggcggt tgaacctgta ccaagacata accaatttca
    14641 gaaggggtac atctaacagg gattcctaac aaatatttgg gcttcaaatg accttgttac
    14701 ctaaaaaagc atgattcggt ggaaaatttc taaaaagaaa aaaaaagaaa acagacatgg
    14761 caggcgataa agaagtctct ttttttcaac taccgcaggg gtcgtctctc ctggtattgg
    14821 atgagaaaaa agaaaggatg ttgtgatgat taaaaacttg tttgtcacaa gacggatagg
    14881 taacggcaag cctgcatcag tcgatgtatg tcgagctttg gctttggata cacaagacaa
    14941 aatattcgaa tgcaccaagt ttgtgcatat atgtaatttc actatcttat tcaaatagct
    15001 gactgaaaaa ttcagtacag ttttgtagct tggttgtttc tttccaagca caccggataa
    15061 catggctatt actgcaatgg cgcagagccc ctggttgtgc acacacccat aacccctacc
    15121 tgtcgagcaa gcgaaaggta gttgtcaccc ttttgattaa aggatgcaat gtataagtca
    15181 cccgcaagcc cccttgcaat agaaagcaac aggtactaat tagtcattga ttttaaagaa
    15241 cgaatatgag caaagaaagc ccttgcttgt cctgcctgat tgtttaccgg tctctaaaga
    15301 gttgaaccct ctgtctgacc aaagtctatt caaaaactgc accgtttgaa cagggcgttg
    15361 ctccactacc tacttcgaac ctcgttcggc gtaatggaaa gattttaacg gcaataagga
    15421 ttcaaatact tattcccaag caaatcgtgg tgatttgtat taaattttcc caaagagaaa
    15481 atgagtgagt atgctaacag tgtctatccc tcttttggag atccctctga agttcctata
    15541 caatggtgga aggcacaggg tcgccaggga cactgacgag taatctagct aattgattgt
    15601 ccgcacaact actatgtacc taaagctcaa catatctcag ttcaatagtc gggccgctca
    15661 agcggggcat cgctttactc cgactccgaa ccatgatcgg cgttattgga gcccctctgc
    15721 ggcagaaaga tcccatggtt tttaaattga cactcagggg ttttatttcc caatcaatcc
    15781 tagccttaca gtactggtgg tacactccga aaggctccac aaatacaaga actggggttc
    15841 gacaatggat gtctcactcg cgtacacccc aactagtctc agtgctcaga ctagaccccc
    15901 ctgcgttgca gggtggaccg aacgctccat ataccatagt accttccagc cacatggctt
    15961 ttcgaccaat caatttggcc ggaaaaatgg cgcccgttct actccgtagt ttgaggacat
    16021 tttgtcggtt attcccgttt acggaagtaa caaacacagt tttgagagca gtgcgcgtac
    16081 tgctcaagta aaaggttata tagtaaaaaa acggtgtatt ttttatttac gaatatttaa
    16141 tattgcaggt ggagcaggat tgcctgagaa ttgcattcgc ttccgggaat gagctacgcg
    16201 gtacgcccac agttagagcc aagtcaaaga cgctgttccc gttttcgcgg gccgatgcaa
    16261 tagcctaaaa actcggtgga ttgatcgatc aatcacgtca ggtcataata atatggtcat
    16321 gatggagaat aatgaaatag gctgcatata ttatctatcg atggcttagt gaaaaaggtt
    16381 gcactgtgca ggggcactta ccctgcgccc tttcaaaccc ttagcctctt ccttctccat
    16441 ggtatgtaag tttgcagcac tttataaaac atccgtggtc cgaaatcatt cccaaaattt
    16501 cttgacaatg gcgggagggc ggcgtaatgc gggatggtgg gtcttcggac tccgggtcag
    16561 tcgctttcag atccggtgac tgttatggcg ataagttcgg tgtcttgcgc atggaaagat
    16621 ttggtgaaat tcgaagccgg agaatattgt tgaaaattcc catacagtcg atctgtaggg
    16681 cgggtttctt ggttaatagc acatttttgt tagagccaca aattgttcct ccttagttct
    16741 actttcgctg atactcgtta catttcatca agtgatccat ggcaacatgt tcttgagcat
    16801 caagaggaag ataatcgagc cgtatctggt gatacggcag agcttggcgc ctctcaagct
    16861 gtccaggtgg cagcttacga aaatcatggc ccgcacagcg tttgacgggc tgccgtctgg
    16921 aaccttgatt gtcctggcgg cactgtcatt agcactgctt gttgctgtac tccggatcaa
    16981 atctcaggaa agaacacgct caaaggaaat acctgggctt cctgtagtga agcgaaacca
    17041 tctgcattac ctcgatatcg tcagggaggg gcgagagctg gtaggtgaac ccaaacctca
    17101 caccattgta attttttacc gagaggacaa ttattttccc caagcaacat ctgacacaaa
    17161 agatcagtac cccggacagc ccttcatggc tgtgaacaag cgtcacagtc ttgtggtgtt
    17221 tccgccttcg tgttttaatg aaatcaagcg gcttccggca cataccgcat ctgcaaaaaa
    17281 gttcttcaac actacgaact atggcgactg gagtcatgtc ggcgaagagt ctccagaact
    17341 catcaagtca gtgattgcgg acctgacacg gtcgcttcct gcacgagtgc atactcgaca
    17401 agatgaatgc cgggatgtgt ttgacgaggt agtcgggcgc cgacgtgaat ggaaggagtt
    17461 ccctctgcta atgactacgt tcgaaatcat cactcaaatc aacgcctgtt ctttcgtcgg
    17521 caaaacactc gccaccaaca ggagctgggt caggtccgtg atgatgttgc ccgtcttcat
    17581 ccacgtcggt gtgatgctgc tagacgcttg ccctcttatc gtccggccgt tcatggccta
    17641 tcttacattt ctacccagca tcaaaaaccg atgggatctg acacgcatgc tcgctccggt
    17701 tctgaagaag gatcttgagg agtatcacga ggcgaaggac aagaaggaat tcttgcggcc
    17761 gcgagccgaa ggaaaggtgc ccttcactgg gtttcttctc tcccattaca agtcggctca
    17821 agcatccctc aagcagctga tttccgacta cattcacctc agcttcgact ccacccccaa
    17881 cactgcagcg gtgatgttcc acgccctttg cgaattggct attcatcccg aggctgtcga
    17941 ggctctgcgt caggaacttg acgaggtcat ggttgacgga aagctacctc cgacacatct
    18001 tcaggagcta aggaaaatgg atagtttcct gcgcgagtgc ttccgattac acccttttgg
    18061 tatctgtgag taatctccgt cggcttagtg atactttgtc tgccattctg tgcgtgccgc
    18121 cgtcaagagg ccgcagataa caatggcttt tcttttcttt tcttttctct tttttttccg
    18181 tctcctaact ttgctcaaaa cgtagtcacg cttcaacgcc gcgtcgaaca gcccgtccag
    18241 ctatcggtcg gcccgctcct acccccgggg acgctgatgg cagtcgacgg gcaggcaatc
    18301 gacgggtcct cggagttgtg gccgaacccg gaaaagttcg acgtgtaccg cttttataac
    18361 ctgcgtcaga agctgggcaa cgagaaccag taccactttg cgacgaccag cccggattcg
    18421 cccggctggg gcgacggaac tcaggcctgc ccgggccggt tctttgccgt gaacacactc
    18481 aagatcgcca tggcgcactt ccttcgcaac tacgacattg agattaagcc agagtgcctg
    18541 ccgctgaaaa ccaagcccat gccgagcggg ttcttttcgc ccgacgacag ggcgatcgca
    18601 cgcatccggg cgcgaacttg agattgtcgt ccaagatctt gctaggtttt ggccgtcgtc
    18661 ttggacttct ggctacttaa tgtgtccctc atggggaaaa ctgtacatta cggtatcaat
    18721 tgaagggcga gatcggatga gtcttggaaa aagcaaaaag caaaaaaaat gcggaatatt
    18781 tgccgtgtat tcgatgcgct tctgtggttg tctcttgggg ataggtgtca tccttaggga
    18841 aggtgatgga ttcctgtaaa aacacgagca tgtacggctc ctccacctta cacacttcaa
    18901 ggtagcatgg cggggattca agcaacgacg ttttcctact ttatcatgtt atgtagggtt
    18961 gagaggtctg acttaaaggt gtctagcctt cttaagaacc aacgaagcaa ttgattgtat
    19021 cgctgcccgt tcggttgact gacgaaaata agctccaaaa tatgaaaata ccaaccttag
    19081 cttgcaatac ggggacaata ctttgagagg tactcatctg ctgcgcgatt aatacaagta
    19141 ttgcatgcgc aagtgcgttg gatgttgaat ccaactgtct ggaaacttct cccgtgcgtt
    19201 cctctatttt caaattctcc tacctcgtag ctccaaatgt attcactgtt caaaatcaaa
    19261 ggtagccatt tttgagtaaa atggtgcagg atacagataa aagtaactga tcaagatcta
    19321 aataaaaaaa caattggcgc tctgttgtta gtggtctccg gcccctgatt tatgatattg
    19381 taacaggggc taccgggcga gttttgcttg tcaaaccccg ttaaatccat tttattgcaa
    19441 ttaggtggtc actaattcat ccattgaggc ctacagctta caataggtat tctgtgcgct
    19501 gttaaaaata actctgtagg tgttgatccc tcgatataca tcgccggttt tctttttttt
    19561 tttctggttt tttttttggg gaggggggac cccaacttaa tttcttccat aactcctcag
    19621 atattttcta atgtttgcta tagtgccttt aatctctacc gttctgcctc cattcgaatc
    19681 acccgtgccc tcacctggtc cactgccccc actgccaccc ctggtggtgg tggtgaacca
    19741 gctgtccaga acggcggctg cagccctggg gtcgaggatc cgtcgctcgt cgctggcgga
    19801 cgaccctgcg ccaccgccgt ccccaccttc agtcgaggac tcatctcgag aggagccgcc
    19861 aaggcctcct ctcccctcgt cggagacgac tcgaactcct agcagcccct cgatccgctg
    19921 cagcagctgc cagccgacgt ggatgacaat ttctatctgc atgtcagggt ggtcctccag
    19981 tttgaaaccg ccaatcccga ccccttggac gatggtcggc agggtctgta ggccttggtg
    20041 gcggtcctgc gacgccagca tctggtagat ctcggacagg accacctcgt atcccttgag
    20101 cagccacgtg tagcaggtga gtatcgtcag cgtcatgggc atgtccagcg gctgaggtgc
    20161 tgcgtcggcc gtcgggctgg ctcctcgacc gcgacgatga gcgctgttct ccgtggacga
    20221 gccctcgtgg gcgtgatcga ccgccatggc gcccgggtat acctgcattt ggttgtcccc
    20281 tgtcgagccg acaaactcgg actcgtcgca caggtcagaa tatgaacact ccgagtccga
    20341 agaactgttc tcgaggaatg tcgctggccg caggcactcg atggttttca agaagatttg
    20401 caggccgtcg aaaagattgc tgattgtagt gctcaagtgg ttgttggtgt tgttgttggc
    20461 cattttggac cagtcgccgg cactggattt gccaaaatcc atcagaaatt tcgagctgag
    20521 ctgcgatagg agctgcaggc agctatcctg ggtagctgcc gaggaacggc cactcgcgga
    20581 cccgtggcgt tggtgttgct gcatctgctg gtcgcgtagg ctttggctgc cggcgccgcc
    20641 agtggtcagg gtgctgcatg ttggaacgtt gaagtagctc gaaggtgtga gcggctcaac
    20701 ctgcgagaac ggcaacatgt ggtgcgtctg cgccgaggtg accgtggtgc tagccgcagc
    20761 agtgacaatc cccgcgtttt cctgcagcac cgagccggag agtgggcaga cggctcggcc
    20821 gtccaggtca aatactttgt ccactaggct gaaagtcgtg gtgccatcag aaggggcgcg
    20881 acttgttcga tgtgggcttc tctcgctgcc gggcggtgcc gcgagcgcag cctcggatcc
    20941 gacctcgaaa ccgtcggcag tgcggtcgtc tggcggcccg tttgcgtgac tcggtagctt
    21001 tgaaaagccc agctgctgtc tggaaaacat cggagtggca aacatgtgcc aaggcggcag
    21061 cgactccctg tcctctggtc tgtgagggcc gctactactg gaccacctct gtgtctggcg
    21121 ctgaggcgcc ggctgcgtcg gggaaatgcc cagagatgat tctctaagct gccggtcact
    21181 gacccgcgtc tcttgctgaa acgccgccgg atggccagga gactccgtcg cgcggtgcgc
    21241 cgaatgatgg ccatctcccg ggggttttac actcaggttg gcggtgtgga tacactcggc
    21301 gccagccttc acgcaccgct tgcatggcag cagggcgcct gtgtcgtttg ggccaggatc
    21361 gagcctgatg caacgaagtt tgtggcctct gcaccggtca cacgcacttc gccgtgggtt
    21421 gaacctgtgc attgcaaggg tatgtagggt aggagtatcg catgtggtgg aggaagcaaa
    21481 aagattacgg acatttaaga tattgcctgt atccaggata aaagcttcgc tttataggcc
    21541 tgttataagt tccattctct cctaggttcg tcttggaagc cttgccaagt catcgcattg
    21601 catactgttg tgtatcaata ttgaggaggt tgcagaaagt tatcataatg ccctctccat
    21661 attcaatatg taatactctc tctgtatgta cgtgcgagga cttaaatcga cctgcaaact
    21721 ttaccaaggt tcgtaaagtt tgcaggtcga tttaagcact cgcttgtacc agtttctgat
    21781 aacaaagatt ccaccgtcat agcatcccgc ttcgccattt ccatttcaca tcatgtcact
    21841 aggttttttt ttcggtttta ccgcggtagt aggtatggtt ccagtgggct taccttgttc
    21901 ccacccaacc ttgagccata gcagcagggg caagaaatga tagggcatga ggggttgggt
    21961 catcacgtac ctaatctcca ctttgagatt acatgagacc tgatggttcg atatctgcgt
    22021 ctgtctggcc aacatatccc ttatcgtgct tcaaagctta ctattcagct acaagtctta
    22081 cctgtggaaa gatctaaaag aggaaggtat aggccgtctg cacggcgatc atcactcgtc
    22141 tgaacattgt ttgacatgtc atatgctagg tatcaaagta ctagacgaac tagctagagg
    22201 tgttggactg gaggatgctg catcgggccg tagtggactc gtggggtatc cctggggaac
    22261 ccctgttagc caggggattg taacgcccga gatttgtgtc cgaatctttc cgatacaatc
    22321 ttcaacagtt tagccatcta tgcacaacat acttactaag cttaccctat agactagcct
    22381 actacgtatt aatataatag aagcgccgtt gtggaaacga tgatatcgct agcgaatagg
    22441 gtcccaactt tgaccttaat tccaacacag acttcactga acaaagtttg tgaaatggag
    22501 ttgacctcat gcgtactgct actactacta atgtacacgt acctcgccga accggtgtag
    22561 atctaccgtt tggtgtgtct ttttaaaggg aaaatatccc cctttccccc acgtctgctg
    22621 gtctttctcc tcaaaccaca ttcggcacct tgcaaaatgg ggtttttatc tgccggtggg
    22681 ctgtgggcca gtctctttcg ggcaaggatc tctccaatcg tagagacgga tgaagtcctc
    22741 ccacttaccc tcatcgataa catagccgca gcacgcaacg ccattctaag cgaggtcatc
    22801 cgtttcgacc aagttctgga tgtcgtcaaa ttacgtgacg ggctgacaga gctgattgac
    22861 aaacgtggtt ggagaaagtt gggtggtcga cttcggttgc gagtaggttc acgataactg
    22921 cctaaatcca tctccgctga tccccaacat gctgttcacc cctcctcccc acccacccaa
    22981 gaaaacacat gggaactttt gctgagctga tcactgcaac atggcatagc ccaacgggtc
    23041 tcttgagatc cacgtgccaa gggagttcac ggaggagcgt cctgcttttc gcttcaccag
    23101 ccaggccttc gacatagcca ttgaggagca tgcgcttggc agccaattgc ccaagctgag
    23161 tgatggtccc tcgttacaac ctgggtcaac tagtgtcgac aagttcaacc ttattccgga
    23221 taaacccgaa aagttggatg actacgtcta cagcgaccgc cccattcttg cgttgcacgt
    23281 cacgtctttt accaactcat gcatagtcac acttacctgg tcccacgtcg tcttcggtgc
    23341 caggggcata aaggagctca tcgcagcctg gtcaaaagtg ctccatggcg agcaaaatgt
    23401 acccctatta cttggcactc accaagacgt cctggcgggc atcgggaccg acggcgacaa
    23461 gacggccccg ttccttctcg acccgatcaa gatcaaaggg ctgggcttgg taagaataat
    23521 ttttggactt ttgtgggaga tctggcaaca tcctacggta gagacccggg ccctgcattt
    23581 acccaaacga ttcgtctcgc agctgaggca gaagtgtatg gaggagcttg gggcgttctg
    23641 cagggaagat ccagcaccgt tcatcagcga gggggacgtc ttggaggcct ggtgctcgag
    23701 gtttgtagcc caggcacgtg ccgatgagaa gcccgctcta gtcacgaacg ccctcgacat
    23761 aaaggatcga ttgactgctc cgtggagcag ccgaggtgaa tacctgcaga acaccggctg
    23821 ctgcacgtgg accccggtgc agcccgagac tttgttgaga agccctcttg gtgaactagc
    23881 atacgtgata cgtcgcagca tccaagagct ggccacggac gaccaactcc gcgcccagtt
    23941 gcgcatcttc agatcactcg gacacacaaa gatgctgccg ctctttggaa accccaactc
    24001 ccgcgtgata agcttttcca attggaccaa gttcaacctt ttcgaagtta ccaacctcgg
    24061 cccggcggtg atctcaacgt cgccatcgac taggtccgat gcctctacca gccctatagg
    24121 aaggccagtt tacatgcatt gcgaagctgc gggtgatagt cgaatgctcc gaaactgctt
    24181 caacgtcact ggaaaggatt gggatggcag ctactggatc accgcacatc tttatccgga
    24241 ggattggacc aaactggagg aatacatgcg acagacacag cagcacatta gtgattagac
    24301 gccatgaata attataggcc aaagctccac acgttgttgc tacatacctt acatatgggc
    24361 ttttggatgt gggattacct gtcagacttc ccaggtgcct tggcggcgca taaaaacttt
    24421 tgaaaacacg ggtttgcaca ccgaatatat agatgaattg aaggtcacgt tatgtatcat
    24481 ccacgatccc tcagccagca cctatctttt agccacctaa caccaagatt tgtaacatac
    24541 gtatcgcgac tttttgtgta agacattcct ggtaagtagc cctaatccct aaccttcaac
    24601 gcgcaatcca gaccatgagg tagtagtggt ggtgacggtg atgatacttc ataccccagt
    24661 gcatttataa aatacatgcc tgggaaaaag agacactagc tccaaagtcg tggctgatta
    24721 atagggtaat tttgccagtg atcgggggtg ccaccgtttc ctatcgagac taatcaatct
    24781 cgttcagttc tcaaggtaaa ttacatcacc ctacccgctc acgaactgtt gtgctagggg
    24841 ctaacgcaga gaaatgatga tgatggcgat gtatggctag gtgagctcgc tgcatactcc
    24901 atagtcactc ccgcgcactg taggcgtcat ctcttttatt aaaccactca tcgcttgtag
    24961 ctcaaaaaaa acaagggatt caaagcacct gccactgcat gcgatgaggc ttttggatac
    25021 ctccacgaac ggtccgggtg cgggcacatt gaacccccaa gcccactggg tattgcacga
    25081 caccagggta ttaataaaaa agaacagagc gttatgcgca cccatgggca gtggacctaa
    25141 aggccgaaat gcgaatccat caccccgaat ccgaactact ctcatggcgg gggggggggg
    25201 tgaaaatcgg gccctctctg caagcaaaag tacagttgtg ggcagcgcga acagctgtgg
    25261 gccacacgaa ttcaagaata cccagaagca gttactgctg catcaacgtt aacccatacc
    25321 atagtaagct tgagcattgt tcagggccct tggtaaagca ctccaaaccc cacccgtggt
    25381 ggagggctgg aaataagcga cgagccggct tgccggctac cgagcgcggg ctggattagt
    25441 ctgccccttt tttacacggg gaaagggatg ggtaggggtg ggtggcaacg ggtggacggg
    25501 ctgacagccg agcgggtcat cccgtccgcc ccatttcacc ggccgaaaag acccgtggct
    25561 acctaagggt agttgggtag tatttattgc gggccccttt tgtttgaccc cataggcctt
    25621 tcgggctgtg ccgtgctata tgcaccttaa atgtacatac atacatggga agtgttgcac
    25681 taaaacatcc tcaaaaacga aagctcccct caaatgacta atgccagtga ctagggtaaa
    25741 tatagcctgc gacaggaagt atatattttt ggcaggcctt agtccgaacg gtgccagtcc
    25801 gagcgggcca ccccgaatcc gaggtatgca cgcctagcaa tctagagccc aagattgcag
    25861 ttttttttat taaaaaaaaa aaaaaaaaaa agaagaagaa agaaagaaag aaaaaattct
    25921 agcttggaat aagacgccag tcgcccggga acaaagtgtt gttgatcacg tcagttgaat
    25981 ctcaacgccc tccgggctcc atgcggacta attaataaaa ggacgctgac tggggcttga
    26041 ttatttaagt tgatccgcaa tcgcaaaata cctcctcgta taggagccag tagttgattt
    26101 ctctcctaat tttaatacca cattttcgct cataaaagtg gagcgagaac ctgattttgc
    26161 gaacacaaca tggcgtcatg gcatcacaaa cagcatatgc cgaatctgca aggcagggtt
    26221 gcgtttgtaa caggcggaaa gtaggcttgc cctgactgct caacgcagaa aaagaaatgt
    26281 gacaatccag catttattga tggacacaca aagcttttgc taaccgtgaa atttgcagcg
    26341 caggtatcgg ctaccatacc gtcgtctttc ttgccaaggc gggtgccaag gtgtattttg
    26401 gagcccggtc ggcctccaga gccgaggcgg ccgtcgagag gatgtatcga gagaatcccg
    26461 gcttactgca cgggcaggtc aattggctac aggttgatat ggcatccatg aagagcgttc
    26521 tagctggctg cgacaagttc cgcgcctctg agtcgaagct gaatatcctg atccacaacg
    26581 ccgctcacga aggaagagag ccatccaaca tggcggactc gggggttcaa attacaatgc
    26641 agacaaagta ggggtttccc actgacctgt tttcgattct ggttcctatt cttgtccttg
    26701 gaaagagatt ttcccgctga ttccccatgt tatagtcact tggcagtttt cgccatgacc
    26761 caagagcttc agccaatgct cagaaccgct gccgcagaga aagattccga tgttcgtatc
    26821 gtcaacgtat gttctctcat ccgctgaccc caatttcggt ggacttttga ggcaagaaaa
    26881 gccaaggcgt cgacacggta tatttgcacg ctggagcact gctgataacg catccgttgg
    26941 ctcacacaca ggtgagctcc aatgctccat ctttaactca ctctgatgaa tggcgtccgg
    27001 acttttccga cccccacggc ggggacattc ggtatcctgc tggccaggcc gacggcttcc
    27061 tagcggccat gaagcgatac agtgtatcca agatggccat gaacctgctg accgcggagc
    27121 ttcaagctcg ctatgaccgc gagggtgtgc ctataatggt tatatcagtt tgtcccggag
    27181 cggtatggac gccgggcacc aggcgtgtct taccctggta cctcctaccc gtctcctacg
    27241 ttaacagctg tagtgagatt gaaggtccca aggcagtact ttttgccgca gtggctaatg
    27301 aagttcggga acaagagatg tatttcaagg gacaattcat caatagaacc catctagtga
    27361 tcaagggtca tccagtcaca tataaccatg cagcaggtca gcagctatgg tcggtatcca
    27421 aggagttggt cagagaattc aaagataaag cacgtccaga atgatatctc tgagtctagt
    27481 tgagcataat tgatagagat agcaatcaga ctaaaggctc ccctgacgta aaggtctact
    27541 ttaaacctca agttgacacg gaaaacgttg aggagatgat gcgtcaaccg acgtgacgac
    27601 ggccgatcgt aactcccgtt cttcgttggg acctgaagtt ggtgcccaac aaatctgaac
    27661 atgagctgaa ctacacggag tgggccgaaa ttatcataga gacgcagatg gcactgctac
    27721 ggaagtcaac ccggaaccgt gagcgccggt acggctgtgc gcactgttaa tcccttgatg
    27781 gatggcgcat gagatgtatc catgcggtcc ggcaatgaat cgtcgatgct tggtctctca
    27841 tctttcagcg atggaataaa aaccttagcc atatccctcc aaacaccgaa atcgaaagat
    27901 ttatggacaa acacaatgca aagagaaaaa aagaaggaga gaaaaagaga gagagaattt
    27961 gtcatttgaa tcatcaaaag cctaggctgg gcttggacag acctcaagat accgacatgg
    28021 taggcatata aatgcaccca gttaaccacc gtaagccata atgtaaggaa ttcccaattt
    28081 caaacggtca tattggaaaa caaaatctgc agctcatcag gaggaaaagc taagatcgac
    28141 aagctttttt tcgaggctgt tattatttca caagggtgtg gttatttcac cgccacggtt
    28201 cgactaattc acggccatgt ggatactttt acaatgttat cattttccgg tactcaaagt
    28261 tgggtttgcg cacgtatagt caggtgctgt gcgaattttg tgtggcgtta gttgtggctt
    28321 cctaatatcc tatgtattgt tgattatttg cactgtaaaa gtatccacat ggccgtgaat
    28381 tagtcgaacc gtggcggtga aataaccaca cccagcaaag ccacaattaa accataggct
    28441 caattatgga tctctgggtt tctagtatgt agatagttcc agaaagttta gatatcatgc
    28501 ataaaaatac cgttgctttt gttttattgt ttttacgatt acagcaattg tatgacttct
    28561 attgacagtc aagacaaaag aatttatata tagcttcaag ggggctataa cgccactggg
    28621 atgagactcg cgcgggtcat taaaagttgc gacagtgtcc aggagacaag taggctggac
    28681 caaaatggat ataacatatt gacaattttc aactggtcag cactgtatgc agccataaaa
    28741 aagatctctc tggcatcttc gcccaccctg cggctcgccc tgtaggggtt gcacaagtct
    28801 atatcacatc attgtgactt gggggagaat gaagccataa ttaaaggnnn nnnnnnnnnn
    28861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    28921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    28981 nnnnnnnnnn nnnnnnnnag cctggtattc agggtaaagg cagtgggcgg tgggatacta
    29041 caaggcggtg atgaaaaatt aggacgagaa ccacgttgtt ttggcaaaga tagcatgata
    29101 atttgccttg ttcgttctct ttcattttct ttattatttt tggcggtagg caactgttct
    29161 tcggtgtgac cagctcgtac taggcttcga agggtgtata taatgtatgt ttacccacca
    29221 agtgtagatg caggatatcg tgtagggggg gaactggaaa caatggcgtg aatacgtgct
    29281 ggcgattgaa taacttggac tcttttagac acagccacaa attgaatatg ttggcaagcc
    29341 ctctgcagaa atataggctt cagggataca ttgccccggg cccggcccgt gacgatcggt
    29401 ccgatatatg aattcatgta gacttagata tcttgatgag aaggtgagaa ataacggaaa
    29461 acatgtgtcg gaagtgagag agggtgttga gcccaaagat ttgcgggatc ctgttttccc
    29521 gaaatttctt tgcatgatcg gagtcgctta gtatggtcag gtcttgctcg gagtcgagtt
    29581 tcggacagag caacgccagg tctattatcc gggagtagga cccggagcac agcgtgccta
    29641 tcggggtggt gagacctgaa tcggtccctg gaaacccgct gtggtcttta gtgccgtggg
    29701 gggagttcca ccactacagt acacataatt gtggtggacc cacagcagga cctcgcaccg
    29761 atctccgaat gggtgctggc tggaacttgc attgcagcaa cacagcgacc aatagcagaa
    29821 atcggcttta gggtctatag tgaaaaaata aggtactcaa gattaccctg tacctgcaga
    29881 tgaggtagta gggctccgcc aagtactgta cgtgtattgt gccaaatcct catcggtaca
    29941 ttttcatccc gggggtaact taaatgtatg atagatacta cgtacgtgta gaaagattcc
    30001 aattgcgggc attagaatac caggggtcaa ctaaagcaga tccatgagct ggagctgatc
    30061 atcaagttca cccgattccc ttttgtagag ccaacttccc ttctcaaagt ctgttgagca
    30121 tttcactcat tttcctgaca ttgggctcga attcaacatt tatcagtgat attttctttg
    30181 ccattgctgc ttgagagcca acacatctgg cctcaacacc agatcttgac aataatggcg
    30241 gcaactttta gtgagcccgt tgccatcatt ggcacgggat gcaggtttcc cggccagtgc
    30301 aacacacctt ccaagttatg ggaacttttg caaacgccca aagacctgct gaaagagatt
    30361 ccagaaaaca gattcagcac ggaggcattt taccaccctc agaattacca ccacggaaca
    30421 tgcaatgtgc gacattccta ttttttggag gaggacctcc gcggttttga tgcccaattt
    30481 ttcggcatta accccgtcga agcccattct gtcgaccccc agcagcgcct acttctcgaa
    30541 accgtctacg aaagtctcga ggctgctgga ttgtccatga aggagatgca agggtccgac
    30601 acggccgttt acgttggcgt tatgagcgcc gattttacag acatgattgg acgcgatccc
    30661 gagacctttc ccacgtattt tgccacggga acggcaagaa gtattctcag taacaggctg
    30721 tcttttttct ttgactggag aggtccatcc atgaccatag acacggcttg ttcatcgtct
    30781 ctcattggtg agtataccaa aaaccaattt cgtctcgaac ctcccagcct ttgtctccgt
    30841 ggcgtgatgc taacgcattc gcagtgggtg ttcctaatcg atgatttttt tcgaacacaa
    30901 tcctacaagt gtgttcgaaa gtggtagaga gattaatcaa attctaacgc gcgacgtttc
    30961 cgcataggcg atgcatcagg cagtgcagac tatccgtcgg ggagaatcat ccatcgcgat
    31021 tgcaagtttt attctacatg cttcttcaac catcctctcc gacaatcctg taaagagagc
    31081 ctaggactgg cgctaacaaa ccggactgtg ctgagcaggt ggccggatcg aacctgatcc
    31141 tgggctccga acaatacatc gctgagagca agctacaaat gctttcgccc actggcagaa
    31201 gccgcatgtg ggatgccgat gcagacggct atgctagagg tgaaggcgtt gcagccattg
    31261 tgctcaaaaa gctaagccag gcaattgcag atggtgatca tatcgagtgc atcatccgcg
    31321 agaccggcgc caaccaagat ggcagaacac ccggcatcac catgccaagt gccactgccc
    31381 aggaggcctt aatccggaca acatacaaaa aggccgggct ggacataagc aaacgttctg
    31441 accgccctca gttcttcgag gctcacggca caggtactcc tgccggcgat cccattgagg
    31501 cgagggcagt cagcaacgca ttctttgggc cgaggtctca cttcagtccc acaagtcccg
    31561 acgacacttt gttcgtgggg tcaatcaaga cagtcgtcgg tcatacagaa ggaacagcgg
    31621 gtctggccgc cgtgatcaag gcctcgctgg cactccaggc cggcgtcgtc ccccccaata
    31681 tgcacctgag caagttgaat cccaagattg agcccttcta cggaaatgta cagatcctgt
    31741 cggaagcgcg gcaatggccc aagcttgcag agggcggcgt gcgaagagtc agcgtcaaca
    31801 gttttggctt cggaggcgcc aactgccatg ccattctcga ggcctacgag cccgagtcga
    31861 cacttgaccg gcggcggtat aacaagagga cagggaaatg cttcacgccc ttcctcttct
    31921 cggcagcaac cgaaaatgca ctggcagctc agctcgacaa gtaccgagcc catgtcgctt
    31981 gtggaaacgc gagcgcgccg ggagacctga agaagttatc actgacgctc agcaatcgcc
    32041 gatctgcgct cccttggcgg gcggtagtgc cggcttccaa cagtgtcgag cgcctgattg
    32101 aaaacctcga tcaatgcaac gacttcacca acgaaacatc tgccagctcg ctcggcacaa
    32161 gaccccgtat tctcggcatc ttcaccggcc agggtgctca atggccgcgc atgggagctg
    32221 cactgatcga aagctctccc gccgctgcca agatactcgc gcgtctggac gagagtcttc
    32281 ggttactccc catacgggat cgtccgactt ggtcgctgcg tgaaaagatc ttggagggtg
    32341 ccgaatcgtc ctcggtcgcc atggccttta tatctcagcc tgtttgcgca gccgtgcaga
    32401 tcatgctcgt cgacatgctc agggcagccg gtatcgagtt ttcaggggta ttgggccatt
    32461 cctcgggcga gataagtgca gcgtacgcag cgggatatct ctcttccgag gacgccatcc
    32521 gcgcagcata ctaccgcggc ttccatatga aatcgctgac ccaaaaaaag ggggcaatga
    32581 ttgcggtggg gacctcgtac gacgacgcca aggagctttg cgatcttccg gccttcgagg
    32641 gacgcgtgtg cgtcgcagcg agcaattcgc cattcagtgt gactttgtcc ggcgatgctg
    32701 atgccatcga tgaggtaaag gcgttgatgg acgaggagaa aaagttcaac cgcctcctcc
    32761 aagtcgaccg ggcctatcat tcgcaccaca tgaaggcctg cgcggcagct tacatggcgt
    32821 ctttgcagca atgtggcgtc cgaactctta cgcggacggc tgcctccagc cgttgccaat
    32881 gggtttctag tgtttacgtt cgccattctg cagagctggc tgcagagggc ggtcttgaag
    32941 ccaaatattg ggccagcaac ctgaccatgc ccgtcatgtt caccgaggcg ttacaaaagc
    33001 ttctcggcga ctgcaaagat ggaaaagcct acgatctggc catcgaggtt ggaccgcacc
    33061 cggcgctcaa ggggcctgca gtacagacca tgtccgaatt ccttggtgga cagtccatcc
    33121 catacacagg cgtattgtcc cggggcaaag acgacgtaga gtcgttctcg acaacgcttg
    33181 gatacatatg gcgcaccctg ggagaaggag cagtggactt tcttggctac agccggttca
    33241 tgaacgagga gcaaggagaa gcgacaataa cacccctgaa cggcctgccg acttacccgt
    33301 gggatcacca ccgcaagttc tggcacgagt cgcgtctctc gcgtgcttac aggttcaaca
    33361 aagacccggt caacgagctc ctcggccgtc agatactgga cggcgctccg gatcagctcc
    33421 gctggcgtaa cgtgctcaag cgcaacgagc tggactggct agatggtcac caggttcagc
    33481 gtcaaaccgt cttcccattt atgggatacg tgtctgcatg tgtggaggcc gctatgaaga
    33541 ttcgtggcga tgctaatgtt caatctatcg agctccagaa ttttaaggtc ggccaggctg
    33601 tcgcatttaa tgatgacgac tcgtggatcg agatcttggt cgttcttgac agcatcaagg
    33661 aatccaaagt caaaggaacc aagacgatat cagcccattt cgcatttcat tcctcatcca
    33721 acaatgagac cgtggatatg acaacccacg ccggctgcga tgtccttgtc acgtatggtg
    33781 acagcatcag tgatcttctc ccgccgccag agatccaagc cgatgacgaa tacttcatgc
    33841 tgggtgtcga gtcggatcgg ttctacaacg ttctcgacga catcgggctt gggtatactg
    33901 ggcccttccg agcactctcg gggctgcagc gaaagttggg caaggctacg ggccgtatca
    33961 agaatcccgc gagcagcaag ctttggcgaa agcctcttct cgtgcacccg gcaatgttgg
    34021 atgcgggcat ccagtctatc atgctggcct actgttatcc gggagacact atgatgcgct
    34081 cgatatatct cccgaccggc atccggcggc tcatcatcaa cccagagcac tgtcaaacct
    34141 ttgcgggtga ggagacagac gtactgtttc agtcgtcggc atcagtggac gatcctcaag
    34201 gtctctctgg agacgtgagc atatatgcac ccggaggact ctcttgcaag gcaattcagg
    34261 tcgaggggct ccaaacgcag cctcttttta accccaccga ggcgaacgat ttaaatattt
    34321 tcaccgagct ggtatggggt gttgatcgcc ccgatgccaa agaaatcgtt aacaaggttg
    34381 atgttcagca gctcgatgga gatctgcttt tctcccttga acgggtggcg tactattacc
    34441 tgcgaatttt ggacaagtcc atacctctta gccagcgcac aggcatcgat tggcacttcg
    34501 gtcaactgtt tgcctacgtg gatcacgtcc tctctcgagt ggaacgcggg acgaaccgct
    34561 ttgccaggaa agagtggcag catgatacca aagaaataat cctcgaaatc cttgagaggt
    34621 atcccgataa cattgacctc aggctcatgc gagctgtggg cgaaaacatt gctgccgtta
    34681 tccgtggcga aatcaccatg ttggagccta tgctgcaaaa caatatgctc aacgattttt
    34741 acgtcgtcgc acatggtatg cctcgttata ctaaatatct ggcctctttg gctagtcaaa
    34801 tcggtcacag ataccctcac atgcacgttc ttgaaattgg tgccggcacg ggtggtgcca
    34861 ccaaatcgtt cctcggagcg ctggacgaca aattttcgac ctacaccttt accgatattt
    34921 ctagtggctt tttcgaaaag gcgaggagtg tatttgcgtc gtatagtgcg aaaatgagct
    34981 tcaaaatgct taatatcgaa aaggatatcg gagaccaggg attcgtcgaa gggtcctacg
    35041 acgtggttat cgcatctttg gtccttcacg ctacacgaaa tttgggccaa acgcttcgaa
    35101 atgtccgccg tcttcttaag cccggtggct atctcctgct tcttgaaatc acagaaaacg
    35161 accagatgag atttggcttg ctttttggtg gtctcgaagg ctggtggctc ggctacgacg
    35221 acggccgagc cctatcccct tgcattaaca tcgaggaatg ggagaaatac ctgaagcaga
    35281 cgggtttctc ggggatcgac acgttaatgc cccatgatga gatactcccc gttcctttgt
    35341 ccgtcatcgt atctcaggcc gtcgacgaaa ggaccgagct cctgaaacag ccgttgcagc
    35401 gactggatcc atcgacaaca ctcgtgccgc agctgacaat catcggcagc ggggcattgg
    35461 cagaggaagt ccatcgtctc ttgcgcccgt tctgtggccg cgtcaacgtt atcgagtcgc
    35521 tcggccacat gggtgccgac caactccctg ttggaggtgc cgtaatctgc ctggctgaca
    35581 ttcaggagcc ggtcttcaag tcgatggacg cagacaagct gcgtggattc cagacaatct
    35641 tcaagcagtc cggcagtgct ctctgggtta ctcagggcac cctcaacgga aacccctact
    35701 cccgcatggt gataggattc ggccgcacaa tagtactgga gatgttgcat ctgcgcttac
    35761 aattcctcga cctcgatcac gaggcacctg ctgatcctac tgcgattgtc gagactttta
    35821 tacgcctgca cctggcagag aactggaaga acgacggcgt gaagatcaca cctttactcc
    35881 actcggtcga gcccgaaatg cacattgata aggagggtcg ggggttcatt cctcggttca
    35941 agctgaacaa gaaacagaac gatcggtaca actcgggacg acgcaagata gtcaaagaag
    36001 tgccactccg acaacagccc gtcgaacttg ttccgcccaa gtcggaagat gcctcatggt
    36061 tgctggcaga gggcaagaat atgcctgagc tcaaaggagc catagatatt gatgtctttt
    36121 acactgtcac tcgggccgtc gaggtatcgg gaggaacttt tctgtacgcc gtgctggggg
    36181 caagacgaga cacgaaagag gtggtgctag cgctttcgcc gacgcaggct tccatcatca
    36241 gagtccctca agcttttatc attcctgctc aggactcagt ggaatatctt caattgttct
    36301 acacagagct ccttgcccgt gccgtcctca gagacgttgc ggccgggaca gttgttgtcg
    36361 ttctgcgacc taccagcatg cttagctgcg cggtcgatcg tctcgccgcg gacaggggag
    36421 ccagagtcct ccatcttgcc gatgaacctg gctcggattg ggactacctt catcacaaat
    36481 cctcaaaagt ccaagttcag gactgggtga aatctaggct cggaaccgaa gctccacccg
    36541 ctgtgttgct actagatttc ggcgcggacc agttcctctt ggcatacctc ctggaatgcc
    36601 tgccggcaga ggttactcgg gccatggttg gcgctcagtc cacttcctcc aaggcgcgta
    36661 tgaaactggg gcagtcggag caggaaatca ggtctttcct cgctgatgtc aggtatgccc
    36721 tgctgccagc ccagcaaaca caccaatcga gcaaagggcg ctcaagcttg aaggttttca
    36781 ctctggagca cttgacaacg aacagagctg gcagcgacgt gtctgtggtg tcctggcctg
    36841 ccggcaccag caccattcca gttcaggtcc aacctgtcaa ttccaaggtc accttcagca
    36901 atgacaagac atactggctt gttggccttt ccggcacttt gggtctgtca ctctgtgagt
    36961 ggatggctca gcagggggct cgttatattg tcatcaccag ccggaatccc aacgtcgacg
    37021 agaggtggaa aaataaaatg gaaaaattgg gaatcaaggt cgaaataatt gccaacaaca
    37081 tctgcgaccg aaagtccgtc cgatccgtct acagccacat ctgtcaaacc atgcctccaa
    37141 tcggaggagt cgcccaagga gccatggtcc ttcacgatac tgcgttttcg gagcttgatt
    37201 tggaacgaat taacaaagtg atgcaaccaa aagtgaatgg gagtatttat ttggaagaga
    37261 tattccataa cacccctttg gaatttttcg tctttttttc ctccatggct tgcgtaactg
    37321 gaaatccagg ccaatccgcc tacgccgctg ccaacatgtt tatgtcgggc ttggcggttc
    37381 aacgtaggaa aagaggcctt aatgcctccg tggtacacat cggtgccatc ttcggcaacg
    37441 gttacgtgac cagagagttg agcctggaac agcaaaattt cttgcgcaag gtcggcaaca
    37501 tgtggctttc ggaacaagac tttagacagc tgtttgccga ggcggttctt gccggtcagc
    37561 ctgagaatac gggatctccg gagctctcca ccggaatgat gaccatagat aacagcgaag
    37621 gcaccaagga aaacatcact tggttcgata atcccatgtt ccagcactgc atcaaagaga
    37681 gcacagacgg taaattgggt ggccagaccg ccaagggtcg agccgtgccg gtgaagactc
    37741 aactcctaga ggctatcaac tcggccgagg tctacgagat tattcacggt aagagattcc
    37801 caaccttcat ttttgataat tctcatttat ttactgacat gtctttccag atgcatttgc
    37861 tgccaaactg cggtctagtt tgcagcttga agacgatcgg cctattgttg atcagacagc
    37921 cgacacactt ggcatagact ccctcttcgc cgttgacatc aggtcatggt tcatcaaaga
    37981 gctccaactt gagatcccgg ttctcaagat cctgggcgga gcaacagtcg gcgagatcct
    38041 cgagactgcg caacagttgt tacccatgga gctgctcccc aagatggacc ccaacgacaa
    38101 gagccccgcg aggaaactaa aagcacaacc cgacagcagc ccagacaagg ctgcttcggc
    38161 tgaaaggtct cgtgcaaaag cccaaacggc catcgaaaac gatggtgacc gcaagtttgc
    38221 tgctacaagg gcggaatccg gcgccaagaa aggagaaaca gtctccaaga aagtggaagc
    38281 cgtcacgcgc ccctcggtgc agtggcaggt gcctgttgaa cccagtacag cggtcggtga
    38341 tctggatgac aaatcgtttc ctggtgaaga tggagtcaga ttaagggctg gtagtttgga
    38401 cacgaccttt acccacaagt cttctgcttc ttcgagtgcg tcgattttgg acgcatctga
    38461 agaccaatca gccgactcgg tgtggtctct tgacacggta aacaacgagc ttgccgtcag
    38521 caagaaaacc ccaatctcat tcgcccagtc acggatttgg tttttggaaa agttcctgga
    38581 ggatcctgcc tcagcgctaa acatcactct gacgattgag ctcgacggct ctctggacgt
    38641 cgatcggttc gggaaagcag tcaagcttgt tggtcagcgc catgaggcgt tgagaacgcg
    38701 attcgtacat ggagacgatt ttgatgcgcc catgcaagaa gtccttgttc actcgacgtt
    38761 gagcttggag caacaagaca tagccagcga cgcggaggcg gatgaggtgt atcgcgaatt
    38821 gcaaaaatac agatacaagc tcggtgaggg cgagaacatg aggatcatac ttctcaaaaa
    38881 gtcaaaccaa ttattccacc ttgttattgg ataccatcac ataaatatgg atggcgttag
    38941 tcttgaagtg gtcctccgcg aattgcaaat ggcgtacgat tcaaaaagac tcccgaactt
    39001 tggcaccatt ctccagtatc cagattttgc cgcactacag cagaaagaat acaaatcggg
    39061 agcatggcaa gacgaaatcg agttttggag gaaggagttt gatggtcgtc cgccctctgt
    39121 tctcccactc ttgcctatgg ccaagactcg atcacgcaca gcgctcacat cctactcgag
    39181 ccacactgcg gaattcagcc tggaccaaat aacactcgct ggcatccagt ctgcttgcga
    39241 atcttccaag gccaccccgt tccaattcca tctcgccacc ttttatgctt tgttgtcccg
    39301 aatggtggat gcggcggata tctgcatcgg catcggctcg gcaaacaggc acgataccgc
    39361 catgatgcag agcgtcggca tttatttgaa cctcctcccc atagtactca agtctcagcc
    39421 caacgagacc tttgccagca ctcttaaacg agtacgaagc aaggtcatga ctgcattcgc
    39481 tcactccagg gtgccgttcg acgttatcgt caacgagctt ggtgcgtcac gcgccactac
    39541 ccacaaccct ttgttccaag ttttggtcaa ctatcgacag gggacagcaa cgaggagaag
    39601 tttctgcggc tgccagagcg aggtcagatc ctttgagcaa ggacaggctg cgtacgatct
    39661 cggcctggac atcatcgaga accccggggg agagtgcaag gttatcatga ctggccagtc
    39721 gacactcttc gtgcctgaag atatggatat gctgaaagat atgtaccaac gacttctgtt
    39781 ggccttctct cgcaatcagg ctctacgatt ggcgatacca tcgctttacg acccagaaat
    39841 ggtaaaacac gcgcttagaa tcggacgagg taggttgaag atggtaaaat cctttctcag
    39901 tgctctcaac ttactaactg aaatttgata taaaaaaaaa caggtccctc gtacactcac
    39961 aaatggcccg agaccttgat ccaccaaata gacgacatag ccaagcaaaa gagccatagc
    40021 ctggccattg tagacggctc cggaacattt ttgacctatg cgcacatgtc aagaagaacc
    40081 aacgccattg ctgcctcgct gcgtggcatt cgacgcggga gcagagtcgg tgtccatctc
    40141 gaccctggag cagactgggt ctgctccgtc ttggccatta tgcggcgaga tgcagtatac
    40201 ctgcctctcg atgctgtctc gggatattct cgattgtctg ccattctcca agatagcaag
    40261 ccggacctgg tgctagtgga caactctacc gagaaggatg ctacagctta tttctcgcct
    40321 atactggcag cagaccagat cttcaatatc gatactgttt cggtcacccc gcccgagact
    40381 ttggccatcg cggcgaagcg aggttcggtc gctgcactca tgtacaccag tggttccacg
    40441 ggagttccca agggaatcat aatgaagcat gagtcttttc gcaacaatat tgagatcata
    40501 tcagagaagc tgggctacaa caatggtcac actgtcacac ttcagcagag ctcatttaac
    40561 ttcgacatgt ctctaggcca aatcttcctg gcgctttcga caggtggaac acttcacgta
    40621 gtaccaagac atctccgggc agaccctgtg gcgatctctt ccatcattgc cctccacggc
    40681 attaccaaca cttcagcgac tccttctgag ttcatcagct gggtccgata cggaagcgtc
    40741 gaagaattgc gcaactcggc ttgggcagca gtgcacagcg gcggcgagcc cgtgagggat
    40801 agtttgaagg ctgccttcct cacggtcaac aagccaggac tgcgcctcct ggactgctac
    40861 ggacctaccg aggtcacatt ctgcagccat attagcgacg tcgactacgg agcggaagag
    40921 accagcatga acaagggact tgaggtgttg cctaactacg cgacctacat tgtggactcg
    40981 ggcatgaaac ccgttcccgc cggcgttccc ggggaggtac tgatcggagg agccggcgtc
    41041 gtggccggat atctacacac agaactaaac acccgaggtt ttgcacatga cagcttcgct
    41101 tctgacgagt tccgcaagca gggctgggag cagctgcatc ggacgggcga ctttgggcgc
    41161 atcaacaagc tcaacgggcg cctgctgctt gagggccgca tcgcggacga cacgcaggtg
    41221 aagctgcggg gcctgcggat agatttgaag gagatcgagg ctgccatggt ccgcgccgcc
    41281 aagggagaca ttctcgactg catcgtcagc gttgcacagt cggccgacgt gtcagacgag
    41341 tacctggtcg catatgccac cgcccgcccg gatgccagca accatcgtct tgagcacctc
    41401 atgcaccaac ttcctctacc tcaatacatg aagcctgcca cgctcgttct tttggaaaag
    41461 atgcctacca acgcgtcagg aaagattgac cgatccgcgt tcaagtcgat tccactccca
    41521 aaggccaccg aagacaatgg aatgcagccc gaggttggcc aggacctcaa cgacaccgag
    41581 tcgcggttga agcagttgtg ggagggtgtc ctgcccaaac acgtcttttc ccagcacaaa
    41641 ttcacagccg cgtccgattt cttcaacgtt ggcggcagtt ccatgttgct catcagcctg
    41701 cgagccaaga tccaggacac ctttgcggtg gtggtttcgc tcttccagct cttcgaggcc
    41761 agcaccctcg gggatatggc ggccctggtc gacgagcttt cgagcggcag tgctgaaaaa
    41821 acggcaggtc ccaacagcgc tttggacatc aactgggaag acgaaactgc cgtctcgcca
    41881 gcgttgctgg gtattccggt ggaaaaaaag tttttcacaa acccggaaat tgttgtgctt
    41941 actggatcga ctgggttttt gggccgagcg attctcacgc gtctattaaa cgatggtatc
    42001 gttaaggaaa tccactgttt tgctgtgcgg gaggagattc ctttattcga ttcacccaag
    42061 attatcgtcc accgcgggga tttaacgctg ccgggattcg gtttgtccca gaaggagctc
    42121 gcaagcatat tttctaaagc ccacgccgtt atccacaacg gtgcagatgt ttcttttgtt
    42181 aaatcttacc acagtttgaa gcccgccaat ttggaagcca cgaaacagct ggttgacctg
    42241 tgtttacctt atcaaatatc gtttcattac atttcgaccg ccgcagtcgt aaacctaacc
    42301 ggcgaaaaaa gctgggagca acgatccgtg ggccggttcc caccgcccgc cggaaccgat
    42361 ggctacatcg cgacgaaatg ggcttcggaa cggtatttgg aaaagtttaa cgatcaatac
    42421 gggctcccga tttggatcca ccggccgtcg tccattaccg ggccgggagc acccgccaac
    42481 gacctcatgg ccaacgtggt cgaattttcg cgcagtaccg cggcaaccct gaacacaaat
    42541 tcctggagcg gttggctgga tttcatttcg gtggacgagg cggcgttgca aatcgtcgac
    42601 gaggtgtacg aggattattc gtggccgggc cacgttaaat acctgtacga atcgggtgag
    42661 cgggtcgtcg cgctcgaaga tatgaaaaac gtgttggaaa gggaagtcgg gtccgttttc
    42721 gaggttgtcg atgtggagga atggattagc agggctgaaa agcaaggatt taaccctttg
    42781 ctaggagagt atctgaagcg tgtcgccaat gcccctcttg tttttcctaa actgattcga
    42841 cacgaaggtt ttttttaaaa cctagctttt tttcaatttg caatcatgtt caactaagat
    42901 attcctgatg gctgggtaac gcacactaac gaacacgtcc aggcagaatt aatagggtag
    42961 gagagccata tattgggtta aatagcgcta tttagccaaa aaagcgcgga agctctttta
    43021 tcctgctttt aacgttaatt taacgctcgc tattatataa taattcgatt tatcggatta
    43081 tttaatacga tatacccccc aattaacccc taatattata ttagggatta attgtaatat
    43141 aacccaaata taaccttttt aagccgtatt ttaaatgcgt atatttattt acaaaataaa
    43201 ggaaaaataa tattaaataa cggtagcggt ataaggcgta ccgtaatttt attttattat
    43261 tatattaaac gtaggcggt
//
