LOCUS       BGC0001884             41956 bp    DNA     linear   BCT 19-OCT-2018
DEFINITION  TPA_exp: Fischerella sp. PCC 9339 aranazole biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0001884
VERSION     BGC0001884
KEYWORDS    Third Party Data; TPA; TPA:experimental.
SOURCE      Fischerella sp. PCC 9339
  ORGANISM  Fischerella sp. PCC 9339
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Hapalosiphonaceae; Fischerella.
REFERENCE   1  (bases 1 to 41956)
  AUTHORS   Moosmann,P., Ueoka,R., Gugger,M. and Piel,J.
  TITLE     Aranazoles: Extensively Chlorinated Nonribosomal Peptide-Polyketide
            Hybrids from the Cyanobacterium Fischerella sp. PCC 9339
  JOURNAL   Org. Lett. 20 (17), 5238-5241 (2018)
   PUBMED   30141631
REFERENCE   2  (bases 1 to 41956)
  AUTHORS   Moosmann,P., Ueoka,R., Gugger,M. and Piel,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-AUG-2018) Institute of Microbiology, ETH Zurich,
            Vladimir-Prelog-Weg 4, Zurich 8093, Switzerland
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Newbler v. 2.3
            Assembly Name         :: aranazole cluster
            Coverage              :: 30x
            Sequencing Technology :: 454; Illumina
            ##Assembly-Data-END##
            ##antiSMASH-Data-START##
            Version               :: 8.dev-5707d64f
            Run date              :: 2025-08-15 20:29:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start           :: 0
            Orig. end             :: 41956
            ##antiSMASH-Data-END##
            THIRD PARTY DATABASE: This TPA record uses data from
            DDBJ/EMBL/GenBank entries ALVS01000028.1, ALVS01000029.1 and
            MK045435.1
FEATURES             Location/Qualifiers
     gene            1..1371
                     /gene="arzA"
     CDS             1..1371
                     /codon_start=1
                     /gene="arzA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /product="ArzA - cytochrome P450"
                     /protein_id="DAB41903.1"
                     /sec_met_domain="p450 (E-value: 3.3e-78, bitscore: 253.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPNTLKTPALLQKLQWVIDPVGYMEQAAQQHPDLFTAEIVGFG
                     DTVVFLYDPQAIQEVLTNDRKKFVALSQGNRFLQPIVGDYSIAMLEGERHRKRRQLLLP
                     PLHGERLQAYSQLICNLTDKIFSQLPQNQSFSACVVTQQISVQVILEVIFGLSQGKKRY
                     QELEHLLMLAADIFQSHLAPIVLYFSFLQKDLGFWSPWGKFVRIQQQIDELIYAEIAER
                     REQFNPHCPSDMPRDRIDILSLLLSARDEMGNSITDLEVRCELMTLLLAGQESTASAMA
                     WGLYWVHQLPHVHEKLLCELNSLGGSPDPMSLVRLPYLTAVCHETLRIAPAVMVTFPRI
                     VQESVELLGHRLEPGMVVLGCVYLTHQREDLYPQPKQFKPERFLERQFSPYEFMPFGGG
                     ARGCIGGSLAQFELKLVLATILSKYQLELADHRPEQLRRRGITLAPTNGIKMKRTKI"
     source          1..41956
                     /db_xref="taxon:1174528"
                     /mol_type="genomic DNA"
                     /organism="Fischerella sp. PCC 9339"
                     /strain="PCC 9339"
     misc_feature    1..41956
                     /note="aranazole biosynthetic gene cluster"
     region          1..41956
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /subregion_numbers="1"
                     /tool="antismash"
     subregion       1..41956
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001884"
                     /subregion_number="1"
                     /tool="antismash"
     cand_cluster    1..41956
                     /SMILES="NC(C)CCC(=O)NC(CS)C(=O)C(C)C(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="interleaved"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="3"
                     /tool="antismash"
     protocluster    1..41956
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[18966:41956](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      18967..41956
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     protocluster    1..39034
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[16730:19034](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      16731..19034
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     gene            2003..3328
                     /gene="arzB"
     CDS             2003..3328
                     /codon_start=1
                     /gene="arzB"
                     /product="ArzB - aKG/Fe(II) oxygenase"
                     /protein_id="DAB41904.1"
                     /transl_table=11
                     /translation="MTTTLINDGKPQSNSKTQKLGSSWFRSLKAIIALTIYGLYELVFV
                     HKFFLHTFFRSFVSDVPPPISLKIGYWNKLQFKAILLMRYLLKNQFWGQQWLKRVHRSI
                     LENLNKQDIDFSKLKMPIPTVEPGKISAQEFWKTYVRTNTPVIIKGGSKHTFAYQNWTM
                     EMFRERCGDLKVRIINMSKNEHSDSRFKYEIGTIKDVIDSKGTENKLYLVVCANVFSIY
                     PDLLDEIGCLDFREYVGGNSTFFAGAQLFLGVHSFTGSHTHCERGNSLFFQIGGRKKWT
                     LVHPDYLWLMYPMLEHFFISCGSFVKNDYDQAYLEQYAPLQKYCPKYEAVLEPGDVLFN
                     PGWHWHAVENLTEETIGVGTRWPEVRQKRANQFFDFMQLISPKVWNIKFGLIAKDPNEL
                     VGGVLVELVENVFKKDTELVMLGKEDGVIAREFDKWPKEYQF"
     gene            3521..4729
                     /gene="arzC"
     CDS             3521..4729
                     /codon_start=1
                     /gene="arzC"
                     /product="ArzC - aKG/Fe(II) halogenase"
                     /protein_id="DAB41905.1"
                     /transl_table=11
                     /translation="MLTIYGIYEVVFVHKFFLHTFFRSSISNVLPPISLKIGYWNKLQF
                     KAILLMRYLLKDQFWGQQWLKRVHRSILENLNKQDIDFSKLKMPIPTVEPGKISAQEFW
                     KTYVRTNTPVIIKGGAKHTFAYQNWTMEMFRERFGDFKVNIANQSKNDELNVGTFKDVI
                     DSSESEDKLYITFYADIFSAYPELVDEVGCLEFREYMGGNAALFAGAQLFLGAKSSTGS
                     GAHCADGNNLFFQIHGKKKWTFVHPDYLWLMYPMLNRFFLFCGSFLKNEYDPVYLEQYA
                     PLQKYCPKCEAVLEPGDILLNPPWQWHAINNLTEKTIAVATRWSLVKQKRANTFFDFMQ
                     LFSPHIWRMRFDLLTKDPNEIGGVLDERTDNLFEKKDDFVVMGKGDAMTTWQFDKWPKK
                     YQF"
     gene            4821..6158
                     /gene="arzD"
     CDS             4821..6158
                     /codon_start=1
                     /gene="arzD"
                     /product="ArzD - aKG/Fe(II) halogenase"
                     /protein_id="DAB41906.1"
                     /transl_table=11
                     /translation="MTTTLIKERKSQNDKKMKKLSPSWFRALIAIVVLAIYGIYEVVFV
                     HKFFLHTFFRSSISNVPPPIALKIGYWNKLQFKAILLIRYFLKDQFWGQQWLKRVHRSI
                     LENLNKQDIDFSKLKMPIPTVELEQISAQEFWKTYVRTNTPVIIKGGAKHTFAYQNWTL
                     EMFRERFGDFRTDTVNLSSRNEYNGGTLHNVSTFKDVIDSRESNEKLYIVFCTDIFSAY
                     PELVNELSCLDFRAHMGGNAALFAGAQLFLGAKPLTGTDAHCADGNNLFFQICGKKKWT
                     FVHPDYLWLMYPMLDRFFLFCASFVKRDYEQVYLDQYAPLQKYCPKYEAVLEPGDVLLN
                     PPWQWHAIDNLTGDNIAVATRWSLVRQKRANTFFDFMQLFSPKIWRIRFDVVTRDPDAV
                     SILDKRTTDDLVKNKSVKSEEDFVGLGNEDGVTAWDFDKWPKEYQF"
     gene            6482..7402
                     /gene="arzE"
     CDS             6482..7402
                     /codon_start=1
                     /gene="arzE"
                     /product="ArzE - Rieske protein"
                     /protein_id="DAB41907.1"
                     /transl_table=11
                     /translation="MVKPLHYFGKDLVLFRTEDGKAHVLDAYCPHLGAHLGYGGQVKGH
                     TIRCPFHGLCFDSHGYCTHTTYAQKLNSNIRFWLVHETNGLILVYYDAQGKLPHWEIPT
                     LPEYNSKEWTQFQPVGRWKIRAHVQDMGENIPDIYHASALHSTLILDHTVFVEGPFWRE
                     LFNVKPVNNQKAPFLNIEVVGNYEVTSYGLGYTVSKQRLHHKAMLELRLILRYTVTPID
                     TEYVDLRFDISVKKFINSAITLAFTKPVFKALKTELEKDLIIWENKIYYSRPLFLEGEE
                     EIIEYRNWANQFYSEIPALNTKTLA"
     gene            7580..8902
                     /gene="arzF"
     CDS             7580..8902
                     /codon_start=1
                     /gene="arzF"
                     /product="ArzF - aKG/Fe(II) halogenase"
                     /protein_id="DAB41908.1"
                     /transl_table=11
                     /translation="MTTTLINDGKSQSDGTTKKVNLNWFRILKAIIILTIYSIYEIVFV
                     HKFFLHTFLRSSISDVPPPISLKIGYWNKLQFKAILLMRYLLKNQFWGQQWLKRVHRSI
                     LENLNKQDIDFSKLKMPIPTVEPGKISAQEFWKTYVRTNTPVIIKGGSKHTFAYQNWTM
                     EMFRERFGDFKTDLISQSRDEHGASTFKPVVHTFKDVINSRESEEKLYIAFCADIFSTY
                     AELVDEVGCLEFRKHMGGNTTFFAGAQLFLGAKALTGSDVHCANANNLFFQISGQKKWT
                     FIHPDYLWLMYPMLDRFCLYCGSFLKREYDQAYLEQYAPLQRYCPNYEAVLEPGDVLLN
                     PPWQWHAIDNLTGDNIAVATRWTDAIGQKRANTFFDCMQFFSPYIWRLRFDLVTKNPDA
                     VGVLDERTNNLVQTQDDYVGLGNENGVIAWEFDRWPKKYQF"
     gene            8994..10289
                     /gene="arzG"
     CDS             8994..10289
                     /codon_start=1
                     /gene="arzG"
                     /product="ArzG - aKG/Fe(II) halogenase"
                     /protein_id="DAB41909.1"
                     /transl_table=11
                     /translation="MTTTLINDSKSQSNGTTKKPIPSLFRTFTAIVISVIYGIYEVVFV
                     HKFFLYTFFRPFVSDVPPPVQLNIGYWNKLQFKIILIMRYLLKDQFWGQQWLKRVHRSI
                     LDNLDRQSIDFSKLNMPIPTVEPGEISAQEFWNTYVKTNTPVIIKGGSKHTFAYQNWSL
                     EMFQERFGDFKVNITNQSKNDEPDICTFKDVIDSEDKLYISFCADIFSAHPELVAELGC
                     LDFKKYMGGNATYFIGAQVFLGARSSTGTHPHCANGNNLFYQIRGKKKWTFVHPDYLWL
                     MYPMLDRLSFFCASFLKRDYDQAYLDQYAPLQKYCPKYEAILEPGDILLNPPWQWHAID
                     NLTGENIAVATRWAPATGQKRANTFFEFIQLLSPYMWGTRFDVLRKQPDAVGVLDEKAG
                     DAVKSQDDFVKLGNEDGLIPWEFDKWPKEYQF"
     gene            10378..11781
                     /gene="arzH"
     CDS             10378..11781
                     /codon_start=1
                     /gene="arzH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /product="ArzH - cytochrome P450"
                     /protein_id="DAB41910.1"
                     /sec_met_domain="p450 (E-value: 1.5e-74, bitscore: 241.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSIPGPKTPSFLQSLQWVFDPVSYLKSTHNRYPDIFMTRNLGLG
                     SPTSVLVSHPQALQQLFTSDRKQFSVPVEFNRILQPLIGEFSIFLIGGNLHAKRRQLVM
                     PSFHGDRIRAYGELIYRITEQVMDQLPPGKSFLALDVMQAISLEVIIKAVFGISKGERY
                     LLLKQNILSLTEPASSPLTSALIFFPNLLQNDWGSWSPWGRFLKRRQQTDDLIYAEIAE
                     RRANPDPNRTDILALLMRSRDEQGQALSDQELRDELMTLLLAGYETTATAITWGLYWMH
                     RLPNVKEKLLNELNSLGDFTSPLEISRLPYLSAFCQETLRICPVAMITFPRISCEPVKI
                     LGYPIEPGTIIAGCIYLTHHREDLYPNSSEFRPERFLERQYSPYEFIAFGGGSRRCVGD
                     ALAQFEMMLILATIACRYQLALADLRPEKLHRRGLALAPSRGVKMVMQKKTKRDDSVER
                     TLALFHHSE"
     gene            12200..13456
                     /gene="arzI"
     CDS             12200..13456
                     /codon_start=1
                     /gene="arzI"
                     /product="ArzI - aKG/Fe(II) halogenase"
                     /protein_id="DAB41911.1"
                     /transl_table=11
                     /translation="MTKKSVQNLFRTLKALVILAIYITYEVAFVHKFFLYTFLRSSISD
                     VPPPIRLKIGYWNKLQFKAILLMRYLLKDQFWGQQWLKRVHRSILENLNKQDIDFSKLK
                     LPIPTVELEQISAQEFWKTYVRTNTPVIIKGGAKHTFAYKNWTLEMFRERFGDFKVNIT
                     NQSRNQHKPDVSTFKDVIDSRESEEKLYISFCADIFSNYPELLNELGCLEFTAHMGGNS
                     VWFAGAQLFLGASSSTGTDAHCADGDNLFFQIRGKKKWTFVHPDYLWLMYPMLDRWFLF
                     CSSFIKRDYDQAYLDQYAPLQKYCPKYEAVLEAGDILLNPTWQWHAIDNITEENIAIAT
                     RWSFIKQKRANTFFDFIQLFSPYIWHMRFGVLKNPDKVDFLEDRTGDVVKNKDDFVKLG
                     SENEVIAWEFDRWPEKYQF"
     protocluster    12551..41956
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[32550:36813](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      32551..36813
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="3"
     gene            13544..14851
                     /gene="arzJ"
     CDS             13544..14851
                     /codon_start=1
                     /gene="arzJ"
                     /product="ArzJ - aKG/Fe(II) halogenase"
                     /protein_id="DAB41912.1"
                     /transl_table=11
                     /translation="MTTTLIQDGKSQSNGATKKSNLSWFRALIAIVVLAIYGIYEVVFV
                     HKFFLHTFFRSSISNVPPPIALKIGYWNKLQFKAILLIRYFLKDQFWGQQWLKRVHRSI
                     LENLNKQDIDFSKLKMPIPTVELEQISAQEFWKTYVRTNTPVIIKGGAKHTFAYQNWTL
                     EMFRERFGDFKVNIVNQSKNEHKPDVSTFKDVIDSRGSEEKLYIAFCADIFSAHPELLD
                     ELNCLDFRKHMGGNSALFGGAQLFLGASSSTGSHAHCADGNNLFFQIYGKKKWTFVHPD
                     YLWLMYPMLDRCFLFCASFVKKDYDQAYLDQYAPLQKYCPKYEAVLEPGDILLIPAWQW
                     HAIDNLTEETIAVATRWSMVKQEQANTFFNFIQLFSPKIWRVRFALLTKGPDEASLALG
                     ERTDDVVQSKNDFVSLGNEHRIITLEFDKWPKEYQF"
     gene            15005..15799
                     /gene="arzK"
     CDS             15005..15799
                     /NRPS_PKS="Domain: oMT (21-235). E-value: 5.3e-69. Score:
                     224.5. Matches aSDomain: nrpspksdomains_arzK_oMT.1"
                     /codon_start=1
                     /gene="arzK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /product="ArzK - O-methyltransferase"
                     /protein_id="DAB41913.1"
                     /transl_table=11
                     /translation="MQVTTNEFINRYDSMILNPLMREYFGQKGFFNLGYWLSNTQSVQE
                     SCENLMEKLLEFIPQKKGKILDVACGLGATTSYLLKYYSPADIVGINISTKQLEKCKVN
                     APGCNFIIMDAVQMIFEDNSFDNVICVEAAFHFDTRERFLQEAWRVLKPGGYLILSDII
                     FKKRLLTDDWMLLENKNVQNIKEYKDLYLKAGFQDIEIIDTTNESWIEFHRRLKPSLLK
                     EYQDGNLDESTYRYYLDITDEKLNSGNQYILVSAKKRKTLEC"
     aSDomain        15068..15709
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzK_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="5.30E-69"
                     /label="arzK_oMT.1"
                     /locus_tag="arzK"
                     /protein_end="235"
                     /protein_start="21"
                     /score="224.5"
                     /tool="antismash"
                     /translation="REYFGQKGFFNLGYWLSNTQSVQESCENLMEKLLEFIPQKKGKIL
                     DVACGLGATTSYLLKYYSPADIVGINISTKQLEKCKVNAPGCNFIIMDAVQMIFEDNSF
                     DNVICVEAAFHFDTRERFLQEAWRVLKPGGYLILSDIIFKKRLLTDDWMLLENKNVQNI
                     KEYKDLYLKAGFQDIEIIDTTNESWIEFHRRLKPSLLKEYQDGNLDESTYR"
     gene            16731..19034
                     /gene="arzL"
     CDS             16731..19034
                     /NRPS_PKS="Domain: CAL_domain (40-473). E-value: 1.8e-129.
                     Score: 424.5. Matches aSDomain:
                     nrpspksdomains_arzL_CAL_domain.1"
                     /NRPS_PKS="Domain: PKS_PP (608-689). E-value: 2.1e-20.
                     Score: 64.8. Matches aSDomain:
                     nrpspksdomains_arzL_PKS_PP.1"
                     /codon_start=1
                     /gene="arzL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /product="ArzL - PKS (FAAL, ACP)"
                     /protein_id="DAB41914.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 3.2e-258, bitscore:
                     850.1, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-94, bitscore:
                     307.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.4e-16, bitscore:
                     48.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKWSTLVDLLRYRAQSQPNRRIYTFLQDGETESDSLTNWELDQQ
                     ARALAAHLQSLDLAGERALLIYPPGLEFITAFLGCLYASVIAVPAYPHLRRKQHISKLK
                     GIVADTHVKVALTSTSLLATIEGQFAQNAELASLQCLSTDKIASKLVSDWRKPEISSET
                     LAFLQYTSGSTGSPKGVMVSHGNILHNSEIIYTCFGHTDDSHVVSWLPPYHDMGLIGGI
                     LQPLYGGFPVTLMSPETFIQKPFCWLQQISRYKATTSGGPNFAYDLCVHKIKPEQLASL
                     DLSSWTLAFTGAEPVRAETMKQFAAAFEPYGFQWESFYPCYGMAEGTLIVSGGLKASPP
                     VIYFVEGAALEQNRVIASVAEGKSVRAIVGCGRSWLDQKIVIANPESLTQCPEGQVGEI
                     WVLGSSVTQGYWNRHKETQQTFKAYLAGTGEGPFLRTGDLGFLQDGELFVTGRIKDVII
                     IRGRNYYPQDIELSIQKIHPSLRPNYGAAFSVEIEDQERLMVAQEVERTCIREINVDEV
                     VEAIRRAVSEQHGLQVYGVLLLKPGSIPKTSSGKIQRYACRVSFLDKSLDIVGDWIGDP
                     RQIDLLQLQTEIDALWEQVQNSTKQLLSKKLKSANQKQRIDILITYLTEIVVRVLRLNE
                     NNLPNPKKGFFDMGMDSLMAVELGNRLQSDLGISFSATTVFEYSNIEELAFHLDKVIPL
                     DVERQKSQSTQQKDRPNEISLKQVSQLSENELQSSIEEELTQLETALQEIGDGQQGLWK
                     WKSTINTATSSAST"
     aSDomain        16851..18149
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzL_CAL_domain.1"
                     /evalue="1.80E-129"
                     /label="arzL_CAL_domain.1"
                     /locus_tag="arzL"
                     /protein_end="473"
                     /protein_start="40"
                     /score="424.5"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="ELDQQARALAAHLQSLDLAGERALLIYPPGLEFITAFLGCLYASV
                     IAVPAYPHLRRKQHISKLKGIVADTHVKVALTSTSLLATIEGQFAQNAELASLQCLSTD
                     KIASKLVSDWRKPEISSETLAFLQYTSGSTGSPKGVMVSHGNILHNSEIIYTCFGHTDD
                     SHVVSWLPPYHDMGLIGGILQPLYGGFPVTLMSPETFIQKPFCWLQQISRYKATTSGGP
                     NFAYDLCVHKIKPEQLASLDLSSWTLAFTGAEPVRAETMKQFAAAFEPYGFQWESFYPC
                     YGMAEGTLIVSGGLKASPPVIYFVEGAALEQNRVIASVAEGKSVRAIVGCGRSWLDQKI
                     VIANPESLTQCPEGQVGEIWVLGSSVTQGYWNRHKETQQTFKAYLAGTGEGPFLRTGDL
                     GFLQDGELFVTGRIKDVIIIRGRNYYPQDIELSI"
     aSModule        16851..18797
                     /complete
                     /domains="nrpspksdomains_arzL_CAL_domain.1"
                     /domains="nrpspksdomains_arzL_PKS_PP.1"
                     /locus_tags="arzL"
                     /monomer_pairings="NH2 -> NH2"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       17223..17282
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzL_0001"
                     /evalue="2.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="arzL"
                     /protein_end="184"
                     /protein_start="164"
                     /score="29.1"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGSPKGVMVSH"
     CDS_motif       17904..17993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzL_0002"
                     /evalue="7.20E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="arzL"
                     /protein_end="421"
                     /protein_start="391"
                     /score="31.2"
                     /tool="antismash"
                     /translation="PEGQVGEIWVLGSSVTQGYWNRHKETQQTF"
     CDS_motif       18078..18140
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzL_0003"
                     /evalue="1.60E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="arzL"
                     /protein_end="470"
                     /protein_start="449"
                     /score="17.5"
                     /tool="antismash"
                     /translation="TGRIKDVIIIRGRNYYPQDIE"
     aSDomain        18555..18797
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzL_PKS_PP.1"
                     /evalue="2.10E-20"
                     /label="arzL_PKS_PP.1"
                     /locus_tag="arzL"
                     /protein_end="689"
                     /protein_start="608"
                     /score="64.8"
                     /tool="antismash"
                     /translation="SANQKQRIDILITYLTEIVVRVLRLNENNLPNPKKGFFDMGMDSL
                     MAVELGNRLQSDLGISFSATTVFEYSNIEELAFHLD"
     gene            18967..26811
                     /gene="arzM"
     CDS             18967..26811
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (39-466). E-value:
                     5.3e-185. Score: 607.3. Matches aSDomain:
                     nrpspksdomains_arzM_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (571-864). E-value: 2.9e-114.
                     Score: 373.4. Matches aSDomain:
                     nrpspksdomains_arzM_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (963-1178). E-value: 2.2e-38.
                     Score: 123.9. Matches aSDomain:
                     nrpspksdomains_arzM_PKS_DH2.1"
                     /NRPS_PKS="Domain: cMT (1413-1625). E-value: 1.2e-99.
                     Score: 325.5. Matches aSDomain: nrpspksdomains_arzM_cMT.1"
                     /NRPS_PKS="Domain: PKS_ER (1870-2188). E-value: 1.5e-118.
                     Score: 387.4. Matches aSDomain:
                     nrpspksdomains_arzM_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2209-2386). E-value: 2.6e-67.
                     Score: 218.2. Matches aSDomain:
                     nrpspksdomains_arzM_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2471-2553). E-value: 1.3e-24.
                     Score: 78.4. Matches aSDomain:
                     nrpspksdomains_arzM_PKS_PP.1"
                     /codon_start=1
                     /gene="arzM"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /product="ArzM - PKS (KS, AT, DH, MT, ER, KR, ACP)"
                     /protein_id="DAB41915.1"
                     /sec_met_domain="mod_KS (E-value: 1.3e-187, bitscore:
                     613.8, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 5.7e-207, bitscore:
                     677.7, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 2.7e-168, bitscore:
                     550.2, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.1e-96, bitscore:
                     312.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.3e-164, bitscore:
                     538.0, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.4e-185, bitscore:
                     607.3, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 5.7e-71, bitscore: 229.4,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 7.7e-115, bitscore:
                     373.4, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2e-18, bitscore:
                     56.8, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.8e-64, bitscore:
                     206.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6e-16, bitscore:
                     48.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNKVCGNGSQLLTQQRLLLALKQANAKLDTIKKAQTEPIAIIGI
                     GCRFPGGANSPEFYWRLLHEGVDAITDVPATRWDINKYYDPKPGTPGKMYSRYGGFLQQ
                     PIDQFDPQFFGISPREAVKLDPQQRLLLEVAWEAIENAGLAAENLRGTQTGVFIGLSTH
                     DYEYSVFGGHLSSIDAYSGLGNARSIAAGRISYILGLQGPTFQLDTACSSSLVAVHLAC
                     QSLRAKECNLALVGGVNLILSPVPTIFFCKTQALSADGRCKTFDANADGYVRGEGCGIL
                     VLKSLSKAIADRDNILALIRGTAINHDGASSGLTVPNKQAQKLLLRQALDNATVNPADV
                     SYIEAHGTGTRLGDPVEVEALGEVFWENCPRLQPLTIGSAKTNIGHLEAAAGVAGLVKV
                     VLALQHQEIPPHLHFSKPNPCIPWNKFPIIIPQSQMPWLRGEKPRLAGVSSFGFSGTNA
                     HVVLEEAPVVEPVPPTVVRPIHLLTLSAKTEAALQELATRYQNHLATFADLDLGDICFN
                     ANIGRSHFNHRLAIVASSSTELKQKLADFTTKEEVTGIFRGQLPSVITRPKIAFLFTGQ
                     GSQYLHMGRQLYETQPTFRKALEQCDAILRNYLEKPLLHILYPQAGETSPIDDTAYTQP
                     TLFALEYALAELWKSWGIEPDVVMGHSVGEYVAACVAGVFSLEEGLKLIANRGRFMQTL
                     VKGGEMVAVLASENQVRDLIKPYESQVSIAAVNGLQSVVISGATHAICTLCAMLESQGV
                     KTKPLQVSHAFHSPLMEPMIAAFAAVVSEVTYSQPCIPIVSNVTGELADEEIATAEYWV
                     DHVQQPVRFADGMQTLHQQGCELFVEIGPKPVLLGMGRQCLTEDVAVWLPSLCPRQGEW
                     QQMLQSLAQLYVRGVAVNWLGFDQGYARRKVMLPTYPFQRQSYWFETTDTPHQTQLLSR
                     GKIFHPLLGQKLNLAGLKHQIRFESQISAKAPAYLSHHQVFGKPLLPAAAYLEMALAAG
                     STLFQIEGLMLEDVVIQQGLILSEEEAKTVQVILTISETQVYDFQIFSLNLEEAQKEPR
                     WTLHTEGKLRIENLETLPSKANLETWQIQCNQQVSVTNYYQQYHDLGIDYGSSFKVIQQ
                     LWRTEGKALGQIQLPQAFVLEADYQIHPILLDASFQVLVAAISTTHFQDIYLPVGVERL
                     RVYRRPSTFLWAQVEIIKEPNSQTLAAEVCLLDADGQLVAIVEGLQAKQATPQALVGNQ
                     QEPLQNWLYEVEWRPQVRFSWQLSSKYLPTPAEIHPQLHSQVSSLINQPDLVIYQDFLT
                     QLESLSIDYVLQAFHQLGWQFQLGQLFSTNLIAEQLGVVKQHHRLFSRLLEMLNEVGIL
                     RSFEDKWEVLQVPLTANPQEQAHTLVQQYPSALAELTLLKRCGAQLASVLQGNCDPLQL
                     IFPEGDLATVTQLYQDSPGAKIMNHLMQQAISLALEQIPKAQGVRVLEIGAGTGGTTAH
                     ILPHLNPAQTKYVFTDVSTLFTINAQEKFRDYPFVSYQTLDIEQNPIEQGFEPHQYDII
                     VIANALHATADLRQSLQNIRQLLSPKGLLVLLEGTSRQRWLDLIFGLLEGWWRFTDVDL
                     RSNYPLLTTSQWQTLLQESGLQLTANLLSTQEDSKVLSQQVVIVAQAVDVLPPSTLHEP
                     KGWLILVDEQGLGSQLAAQLRAKGEACTLVLPGEGYQQVGEQQFIINPNSSEDFQQIVS
                     KVASCQPALYGVIQCWSLETVESKALSSEELKALCQRECGSTLYLIQALVKVGMVQPPR
                     LWLVTRGCQPIPDLHPAISSVAHSPLWGMGKVIALEHPELKCVRIDLDPGTVRDEAQTL
                     FEEIWSEDTEDQVAFREGIRYVARLIRSRQTRESLRKEQLKISHAQPFRLTISTKGTLE
                     NLTLEPTTRRPPSAGEVEIQVKATGLNFLDVVNALGLVPKEVAGVSQEHLLKIDGFGGE
                     FAGEVVSIGEEVQGFEIGDSVIGLAPESFSKYVTVSATLVVSKPENLNFEEAAAIPINF
                     LTAYYALYHVAQISAGDRVLIHAAAGGTGMAAVQIAQQVGAEVFATASSSKWEVLRSMG
                     VQYIMNSRTLDFAEEVMKITRGDGVDIVLNSLTSKEFIAKSLSVVKSQGCFLELAKRDV
                     WNSNLMAEARGDVSYCIIDLLRMSQQQPDLIRSMLLDLMHMFHEGKLQLPPMKVFPIQD
                     VVSAFRYMQQAKHIGKVIVTHSLEQSDSTSERPLTFRGDSTYLITGGLGGLGLLVARWM
                     VDNGARHLVLVGRSGTKDNIRSQLEELQHKGANVIVTQADVSETEAIARVLTDIKQSLP
                     ALRGIIHSVGVLDDGVLQQQTWERFAQVLAPKVQGAWNLHNLTQHQPLDFFILFSSVAS
                     LLGSPGQASHSAANAFLDALAYHRRAQGLMGLSINWGAIAEIGAAAKRQISQRPNKNGI
                     KAIPPQKVLEALEQLMSSSSVEVGVVPICWSEFINQPSLSPFFSDWKKISELPSLTQTD
                     FLQKLLAAPTNNFRELLSEHICLQVAKVLGINSSQSIDLQQGFFELGMDSLTSVELRNR
                     LQTSLKCSIPSTLAFDYPSVEKLVDYLSHEILGTESLKNSAVGLNKGEEKNDKKVEKTS
                     VNIESLSENELEELINQKLKSLIKEEQSGYDY"
     CDS_motif       19009..19026
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0001"
                     /evalue="3.20E+01"
                     /label="PKSI-KS_m2"
                     /locus_tag="arzM"
                     /protein_end="20"
                     /protein_start="14"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="QQRLLL"
     aSDomain        19084..20364
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzM_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="5.30E-185"
                     /label="arzM_PKS_KS.1"
                     /locus_tag="arzM"
                     /protein_end="466"
                     /protein_start="39"
                     /score="607.3"
                     /tool="antismash"
                     /translation="IAIIGIGCRFPGGANSPEFYWRLLHEGVDAITDVPATRWDINKYY
                     DPKPGTPGKMYSRYGGFLQQPIDQFDPQFFGISPREAVKLDPQQRLLLEVAWEAIENAG
                     LAAENLRGTQTGVFIGLSTHDYEYSVFGGHLSSIDAYSGLGNARSIAAGRISYILGLQG
                     PTFQLDTACSSSLVAVHLACQSLRAKECNLALVGGVNLILSPVPTIFFCKTQALSADGR
                     CKTFDANADGYVRGEGCGILVLKSLSKAIADRDNILALIRGTAINHDGASSGLTVPNKQ
                     AQKLLLRQALDNATVNPADVSYIEAHGTGTRLGDPVEVEALGEVFWENCPRLQPLTIGS
                     AKTNIGHLEAAAGVAGLVKVVLALQHQEIPPHLHFSKPNPCIPWNKFPIIIPQSQMPWL
                     RGEKPRLAGVSSFGFSGTNAHVVLEEAP"
     aSModule        19084..26625
                     /complete
                     /domains="nrpspksdomains_arzM_PKS_KS.1"
                     /domains="nrpspksdomains_arzM_PKS_AT.1"
                     /domains="nrpspksdomains_arzM_PKS_DH2.1"
                     /domains="nrpspksdomains_arzM_cMT.1"
                     /domains="nrpspksdomains_arzM_PKS_ER.1"
                     /domains="nrpspksdomains_arzM_PKS_KR.1"
                     /domains="nrpspksdomains_arzM_PKS_PP.1"
                     /locus_tags="arzM"
                     /monomer_pairings="mal -> Me-redmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       19339..19365
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0002"
                     /evalue="4.60E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="arzM"
                     /protein_end="133"
                     /protein_start="124"
                     /score="7.0"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       19570..19617
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0003"
                     /evalue="1.80E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="arzM"
                     /protein_end="217"
                     /protein_start="201"
                     /score="16.9"
                     /tool="antismash"
                     /translation="GPTFQLDTACSSSLVA"
     CDS_motif       19759..19797
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0004"
                     /evalue="9.30E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="arzM"
                     /protein_end="277"
                     /protein_start="264"
                     /score="15.3"
                     /tool="antismash"
                     /translation="FDANADGYVRGEG"
     CDS_motif       19990..20037
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0005"
                     /evalue="3.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="arzM"
                     /protein_end="357"
                     /protein_start="341"
                     /score="12.9"
                     /tool="antismash"
                     /translation="YIEAHGTGTRLGDPVE"
     CDS_motif       20098..20142
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0006"
                     /evalue="2.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="arzM"
                     /protein_end="392"
                     /protein_start="377"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GSAKTNIGHLEAAAG"
     aSDomain        20680..21558
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzM_PKS_AT.1"
                     /evalue="2.90E-114"
                     /label="arzM_PKS_AT.1"
                     /locus_tag="arzM"
                     /protein_end="864"
                     /protein_start="571"
                     /score="373.4"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYLHMGRQLYETQPTFRKALEQCDAILRNYLEKPLLHI
                     LYPQAGETSPIDDTAYTQPTLFALEYALAELWKSWGIEPDVVMGHSVGEYVAACVAGVF
                     SLEEGLKLIANRGRFMQTLVKGGEMVAVLASENQVRDLIKPYESQVSIAAVNGLQSVVI
                     SGATHAICTLCAMLESQGVKTKPLQVSHAFHSPLMEPMIAAFAAVVSEVTYSQPCIPIV
                     SNVTGELADEEIATAEYWVDHVQQPVRFADGMQTLHQQGCELFVEIGPKPVLLGMGRQC
                     LTEDVAVWLPSL"
     CDS_motif       20683..20730
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0007"
                     /evalue="8.90E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="arzM"
                     /protein_end="588"
                     /protein_start="572"
                     /score="18.2"
                     /tool="antismash"
                     /translation="FTGQGSQYLHMGRQLY"
     CDS_motif       20860..20916
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0008"
                     /evalue="1.50E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="arzM"
                     /protein_end="650"
                     /protein_start="631"
                     /score="14.9"
                     /tool="antismash"
                     /translation="YTQPTLFALEYALAELWKS"
     CDS_motif       20920..21042
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0009"
                     /evalue="2.50E-28"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="arzM"
                     /protein_end="692"
                     /protein_start="651"
                     /score="90.5"
                     /tool="antismash"
                     /translation="GIEPDVVMGHSVGEYVAACVAGVFSLEEGLKLIANRGRFMQ"
     CDS_motif       21136..21174
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0010"
                     /evalue="7.40E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="arzM"
                     /protein_end="736"
                     /protein_start="723"
                     /score="9.8"
                     /tool="antismash"
                     /translation="AAVNGLQSVVISG"
     CDS_motif       21394..21429
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0011"
                     /evalue="2.30E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="arzM"
                     /protein_end="821"
                     /protein_start="809"
                     /score="11.5"
                     /tool="antismash"
                     /translation="YWVDHVQQPVRF"
     CDS_motif       21856..21933
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0012"
                     /evalue="1.30E-11"
                     /label="PKSI-DH_m2"
                     /locus_tag="arzM"
                     /protein_end="989"
                     /protein_start="963"
                     /score="36.8"
                     /tool="antismash"
                     /translation="YLSHHQVFGKPLLPAAAYLEMALAAG"
     aSDomain        21856..22500
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzM_PKS_DH2.1"
                     /evalue="2.20E-38"
                     /label="arzM_PKS_DH2.1"
                     /locus_tag="arzM"
                     /protein_end="1178"
                     /protein_start="963"
                     /score="123.9"
                     /tool="antismash"
                     /translation="YLSHHQVFGKPLLPAAAYLEMALAAGSTLFQIEGLMLEDVVIQQG
                     LILSEEEAKTVQVILTISETQVYDFQIFSLNLEEAQKEPRWTLHTEGKLRIENLETLPS
                     KANLETWQIQCNQQVSVTNYYQQYHDLGIDYGSSFKVIQQLWRTEGKALGQIQLPQAFV
                     LEADYQIHPILLDASFQVLVAAISTTHFQDIYLPVGVERLRVYRRPSTFLWA"
     aSDomain        23206..23841
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzM_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="1.20E-99"
                     /label="arzM_cMT.1"
                     /locus_tag="arzM"
                     /protein_end="1625"
                     /protein_start="1413"
                     /score="325.5"
                     /tool="antismash"
                     /translation="QLYQDSPGAKIMNHLMQQAISLALEQIPKAQGVRVLEIGAGTGGT
                     TAHILPHLNPAQTKYVFTDVSTLFTINAQEKFRDYPFVSYQTLDIEQNPIEQGFEPHQY
                     DIIVIANALHATADLRQSLQNIRQLLSPKGLLVLLEGTSRQRWLDLIFGLLEGWWRFTD
                     VDLRSNYPLLTTSQWQTLLQESGLQLTANLLSTQEDSKVLSQQVVIVAQ"
     CDS_motif       23287..23313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0013"
                     /evalue="1.80E+01"
                     /label="PKSI-KR_m3"
                     /locus_tag="arzM"
                     /protein_end="1449"
                     /protein_start="1440"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="PKAQGVRVL"
     CDS_motif       23965..24000
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0014"
                     /evalue="7.40E+00"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="arzM"
                     /protein_end="1678"
                     /protein_start="1666"
                     /score="0.3"
                     /tool="antismash"
                     /translation="LVLPGEGYQQVG"
     aSDomain        24577..25530
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzM_PKS_ER.1"
                     /evalue="1.50E-118"
                     /label="arzM_PKS_ER.1"
                     /locus_tag="arzM"
                     /protein_end="2188"
                     /protein_start="1870"
                     /score="387.4"
                     /tool="antismash"
                     /translation="GTLENLTLEPTTRRPPSAGEVEIQVKATGLNFLDVVNALGLVPKE
                     VAGVSQEHLLKIDGFGGEFAGEVVSIGEEVQGFEIGDSVIGLAPESFSKYVTVSATLVV
                     SKPENLNFEEAAAIPINFLTAYYALYHVAQISAGDRVLIHAAAGGTGMAAVQIAQQVGA
                     EVFATASSSKWEVLRSMGVQYIMNSRTLDFAEEVMKITRGDGVDIVLNSLTSKEFIAKS
                     LSVVKSQGCFLELAKRDVWNSNLMAEARGDVSYCIIDLLRMSQQQPDLIRSMLLDLMHM
                     FHEGKLQLPPMKVFPIQDVVSAFRYMQQAKHIGKVIV"
     CDS_motif       24919..24963
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0015"
                     /evalue="5.70E-05"
                     /label="PKSI-ER_m4"
                     /locus_tag="arzM"
                     /protein_end="1999"
                     /protein_start="1984"
                     /score="16.4"
                     /tool="antismash"
                     /translation="AAAIPINFLTAYYAL"
     CDS_motif       24988..25050
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0016"
                     /evalue="3.20E-09"
                     /label="PKSI-ER_m5"
                     /locus_tag="arzM"
                     /protein_end="2028"
                     /protein_start="2007"
                     /score="29.1"
                     /tool="antismash"
                     /translation="GDRVLIHAAAGGTGMAAVQIA"
     CDS_motif       25060..25107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0017"
                     /evalue="1.40E-03"
                     /label="PKSI-ER_m6"
                     /locus_tag="arzM"
                     /protein_end="2047"
                     /protein_start="2031"
                     /score="11.6"
                     /tool="antismash"
                     /translation="GAEVFATASSSKWEVL"
     CDS_motif       25177..25215
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0018"
                     /evalue="2.40E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="arzM"
                     /protein_end="2083"
                     /protein_start="2070"
                     /score="13.7"
                     /tool="antismash"
                     /translation="TRGDGVDIVLNSL"
     CDS_motif       25483..25530
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0019"
                     /evalue="1.10E-07"
                     /label="PKSI-ER_m9"
                     /locus_tag="arzM"
                     /protein_end="2188"
                     /protein_start="2172"
                     /score="24.4"
                     /tool="antismash"
                     /translation="AFRYMQQAKHIGKVIV"
     CDS_motif       25594..25692
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0020"
                     /evalue="3.40E-19"
                     /label="PKSI-KR_m1"
                     /locus_tag="arzM"
                     /protein_end="2242"
                     /protein_start="2209"
                     /score="61.3"
                     /tool="antismash"
                     /translation="TYLITGGLGGLGLLVARWMVDNGARHLVLVGRS"
     aSDomain        25594..26124
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzM_PKS_KR.1"
                     /evalue="2.60E-67"
                     /label="arzM_PKS_KR.1"
                     /locus_tag="arzM"
                     /protein_end="2386"
                     /protein_start="2209"
                     /score="218.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TYLITGGLGGLGLLVARWMVDNGARHLVLVGRSGTKDNIRSQLEE
                     LQHKGANVIVTQADVSETEAIARVLTDIKQSLPALRGIIHSVGVLDDGVLQQQTWERFA
                     QVLAPKVQGAWNLHNLTQHQPLDFFILFSSVASLLGSPGQASHSAANAFLDALAYHRRA
                     QGLMGLSINWGAIA"
     CDS_motif       25918..25947
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0021"
                     /evalue="7.30E-04"
                     /label="PKSI-KR_m3"
                     /locus_tag="arzM"
                     /protein_end="2327"
                     /protein_start="2317"
                     /score="12.8"
                     /tool="antismash"
                     /translation="PKVQGAWNLH"
     CDS_motif       25969..26079
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzM_0022"
                     /evalue="1.10E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="arzM"
                     /protein_end="2371"
                     /protein_start="2334"
                     /score="66.2"
                     /tool="antismash"
                     /translation="LDFFILFSSVASLLGSPGQASHSAANAFLDALAYHRR"
     aSDomain        26380..26625
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzM_PKS_PP.1"
                     /evalue="1.30E-24"
                     /label="arzM_PKS_PP.1"
                     /locus_tag="arzM"
                     /protein_end="2553"
                     /protein_start="2471"
                     /score="78.4"
                     /tool="antismash"
                     /translation="APTNNFRELLSEHICLQVAKVLGINSSQSIDLQQGFFELGMDSLT
                     SVELRNRLQTSLKCSIPSTLAFDYPSVEKLVDYLSHE"
     gene            26801..32554
                     /gene="arzN"
     CDS             26801..32554
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (36-462). E-value:
                     7.6e-192. Score: 629.8. Matches aSDomain:
                     nrpspksdomains_arzN_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (567-860). E-value: 2.2e-114.
                     Score: 373.8. Matches aSDomain:
                     nrpspksdomains_arzN_PKS_AT.1"
                     /NRPS_PKS="Domain: oMT (1004-1225). E-value: 1.1e-86.
                     Score: 282.9. Matches aSDomain: nrpspksdomains_arzN_oMT.1"
                     /NRPS_PKS="Domain: PKS_KR (1537-1714). E-value: 1.9e-69.
                     Score: 225.2. Matches aSDomain:
                     nrpspksdomains_arzN_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1807-1892). E-value: 9.4e-18.
                     Score: 56.3. Matches aSDomain:
                     nrpspksdomains_arzN_PKS_PP.1"
                     /codon_start=1
                     /gene="arzN"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /product="ArzN - PKS (KS, AT, OMT, KR, ACP)"
                     /protein_id="DAB41916.1"
                     /sec_met_domain="mod_KS (E-value: 2.3e-196, bitscore:
                     642.7, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 7e-211, bitscore: 690.6,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 2.5e-174, bitscore:
                     570.1, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.5e-98, bitscore:
                     319.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.5e-168, bitscore:
                     551.0, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 2e-192, bitscore: 629.8,
                     seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 1.5e-67, bitscore: 218.1,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.9e-115, bitscore:
                     373.8, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.1e-64, bitscore:
                     206.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.7e-13, bitscore:
                     40.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIEQMSQLSPLQRSFLVIERLQSKLDALKDSAKEPVAIIGMGCR
                     FPGGAKTPEALWHLLHDGKSAITEVPASRWDIEAYYDPNPATLGKMYTRYGGFIEQFQE
                     FDPQFFGISPREVLSLDPQQRLLLEVSWEALENAGLNPQQLAGTPTGVFIGICSNDYSK
                     RLLARGLSKIDAHLGTGTAHSVASGRLSYSLGLTGPSVAVDTACSSALVTIHLACQSLR
                     NRESNLALAGGVNLLLSPEITLTFCKARMLSRDGYCKTFDASADGYVRAEGCGIIILKR
                     LSDAVANGDNILAVIRGSAVNQDGRSSGLTVPNGPSQQAVIRQALENGGVDPAQVSYIE
                     AHGTGTSLGDPIEVRALGEVFSSSHSQKHPLIIGSVKTNIGHLEAAAGIAGLIKVILQL
                     QHKEIAPHLHLKQPNPHINWDELPIVVPLHLTPWLRGEKPRLAGVSSFGFSGTNAHVVL
                     EEAPVVEPVPPTVVRPIHLLTLSAKTEAALQELATRYQNHLATFADLDLGDICFNANIG
                     RSHFNHRLAIVASSSTELKQKLADFTTKEEVTGIFRGQLPSVITRPKIAFLFTGQGSQY
                     LHMGRQLYETQPTFRKALEQCDAILRNYLEKPLLHILYPQAGETSPIDDTAYTQPTLFA
                     LEYALAELWKSWGIEPDMVMGHSVGEYVAACVAGVFSLEEGLKLIANRGRFMQTLVKGG
                     EMVAVLASENQVRDLIKPYESQVSIAAVNGLQSVVISGATHAICTLCAMLESQGVKTKP
                     LQVSHAFHSPLMEPMIAAFAAVVSEVTYSQPCIPIVSNVTGELADEEIATAEYWVDHVQ
                     QPVRFADGMQTLHQQGCELFVEIGPKPVLLGMGRQCLTEDVAVWLPSLCPRQGEWQQML
                     QSLAQLYVRGVAVNWLGFDQGYARRKVMLPTYPFQRQSYWFETTDENGYQKTGIAPSEK
                     HKSPITNFLDQGNTEQLTQYLEKTANLSEAQRASLSELLELLVREHQKHLLVKSNIVFD
                     YYNSLSRTSSESSQEKYLTFAPFPKIVPGFSWLLTLAEPQKYQKYMQATLDAQKEMRDV
                     LFAKVDFSSSTKVLDFGCGYGSDLIDLAEKYSHLKLYGYTISSEQAKIATKKIHERHLQ
                     ERVTVFNRDSSKDEFTEQYDLEFGFEVAHHIKDKSALFSNLGRSLKDEGFLVLADFISN
                     ATFPIEHHETSSYFITKEEWVEQLSHNHLKIIDCIDVSQEIANFLYDPNFEENLEKLYQ
                     TNPDDNIRAALQSYNQLGKLLGNGLASYVLLTAQKENHLSKDKIHDLNKQRLNTLVSYS
                     QRAFKQWLYEIEWQPKAFHAIDQNLSQSQKNQPGSWLIFADQGGVGEALAQHLEKQGEH
                     CILFFPGKECEILEAEHWTIDYTNPEKFQQQIKEILKKNKRLCRGVVHLWSLDSSLSEN
                     LTTSLLKATQTKNCGSVLNLVQALAQLEVSELPRLWLVTKGAQVVGQTQTTLQVQQAPL
                     WGLSRVIAKEHPNLRCVCLDLEQTEQSNKIQDIYQELWFSDQEDQIAYRQGVRYVARLV
                     QRSSQVSVSQISVNENSSYLVTGGLGALGLKVAHWMVKQGAKHLILISRREVSDVDQTS
                     VSQLEQAGAQVLVVKSDVSDQMDLARTLQEIKSSMPPLRGIVHAAGILDDGVLLQQNWE
                     RFASVMAPKVEGAWNLHSLTQNLPLDFFVCFSSVAAVLGSPGQGNYAAANAFLDALAYY
                     RRSLGLSALSINWGPWTNTGMVAGLESRHQARLAVQGMGTIAPEQGLQVLGELLGQNTP
                     QVMALPVNWTKFLSHFPADMYPALLLEIAHQEQQQWKLERSPAQQLELLGQLKAANPSD
                     RLELLVTYLQTRVAKILGLGASLQPEPDDSLNELGLDSLMGIELKNRITTELGVNIPLQ
                     KFTEGISIKQLALAVLEELMLTSIIQSNFFSQELNDDVEEITI"
     aSDomain        26909..28186
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzN_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="7.60E-192"
                     /label="arzN_PKS_KS.1"
                     /locus_tag="arzN"
                     /protein_end="462"
                     /protein_start="36"
                     /score="629.8"
                     /tool="antismash"
                     /translation="VAIIGMGCRFPGGAKTPEALWHLLHDGKSAITEVPASRWDIEAYY
                     DPNPATLGKMYTRYGGFIEQFQEFDPQFFGISPREVLSLDPQQRLLLEVSWEALENAGL
                     NPQQLAGTPTGVFIGICSNDYSKRLLARGLSKIDAHLGTGTAHSVASGRLSYSLGLTGP
                     SVAVDTACSSALVTIHLACQSLRNRESNLALAGGVNLLLSPEITLTFCKARMLSRDGYC
                     KTFDASADGYVRAEGCGIIILKRLSDAVANGDNILAVIRGSAVNQDGRSSGLTVPNGPS
                     QQAVIRQALENGGVDPAQVSYIEAHGTGTSLGDPIEVRALGEVFSSSHSQKHPLIIGSV
                     KTNIGHLEAAAGIAGLIKVILQLQHKEIAPHLHLKQPNPHINWDELPIVVPLHLTPWLR
                     GEKPRLAGVSSFGFSGTNAHVVLEEAP"
     aSModule        26909..32476
                     /complete
                     /domains="nrpspksdomains_arzN_PKS_KS.1"
                     /domains="nrpspksdomains_arzN_PKS_AT.1"
                     /domains="nrpspksdomains_arzN_oMT.1"
                     /domains="nrpspksdomains_arzN_PKS_KR.1"
                     /domains="nrpspksdomains_arzN_PKS_PP.1"
                     /locus_tags="arzN"
                     /monomer_pairings="mal -> OMe-ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       27392..27436
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0001"
                     /evalue="1.50E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="arzN"
                     /protein_end="212"
                     /protein_start="197"
                     /score="17.1"
                     /tool="antismash"
                     /translation="GPSVAVDTACSSALV"
     CDS_motif       27581..27619
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0002"
                     /evalue="1.50E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="arzN"
                     /protein_end="273"
                     /protein_start="260"
                     /score="14.7"
                     /tool="antismash"
                     /translation="FDASADGYVRAEG"
     CDS_motif       27812..27859
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0003"
                     /evalue="1.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="arzN"
                     /protein_end="353"
                     /protein_start="337"
                     /score="13.7"
                     /tool="antismash"
                     /translation="YIEAHGTGTSLGDPIE"
     CDS_motif       27920..27964
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0004"
                     /evalue="3.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="arzN"
                     /protein_end="388"
                     /protein_start="373"
                     /score="12.9"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAAAG"
     aSDomain        28502..29380
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzN_PKS_AT.1"
                     /evalue="2.20E-114"
                     /label="arzN_PKS_AT.1"
                     /locus_tag="arzN"
                     /protein_end="860"
                     /protein_start="567"
                     /score="373.8"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYLHMGRQLYETQPTFRKALEQCDAILRNYLEKPLLHI
                     LYPQAGETSPIDDTAYTQPTLFALEYALAELWKSWGIEPDMVMGHSVGEYVAACVAGVF
                     SLEEGLKLIANRGRFMQTLVKGGEMVAVLASENQVRDLIKPYESQVSIAAVNGLQSVVI
                     SGATHAICTLCAMLESQGVKTKPLQVSHAFHSPLMEPMIAAFAAVVSEVTYSQPCIPIV
                     SNVTGELADEEIATAEYWVDHVQQPVRFADGMQTLHQQGCELFVEIGPKPVLLGMGRQC
                     LTEDVAVWLPSL"
     CDS_motif       28505..28552
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0005"
                     /evalue="6.20E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="arzN"
                     /protein_end="584"
                     /protein_start="568"
                     /score="18.6"
                     /tool="antismash"
                     /translation="FTGQGSQYLHMGRQLY"
     CDS_motif       28682..28738
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0006"
                     /evalue="1.10E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="arzN"
                     /protein_end="646"
                     /protein_start="627"
                     /score="15.4"
                     /tool="antismash"
                     /translation="YTQPTLFALEYALAELWKS"
     CDS_motif       28742..28864
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0007"
                     /evalue="2.90E-28"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="arzN"
                     /protein_end="688"
                     /protein_start="647"
                     /score="90.3"
                     /tool="antismash"
                     /translation="GIEPDMVMGHSVGEYVAACVAGVFSLEEGLKLIANRGRFMQ"
     CDS_motif       28958..28996
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0008"
                     /evalue="5.20E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="arzN"
                     /protein_end="732"
                     /protein_start="719"
                     /score="10.2"
                     /tool="antismash"
                     /translation="AAVNGLQSVVISG"
     CDS_motif       29216..29251
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0009"
                     /evalue="1.70E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="arzN"
                     /protein_end="817"
                     /protein_start="805"
                     /score="11.9"
                     /tool="antismash"
                     /translation="YWVDHVQQPVRF"
     aSDomain        29813..30475
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzN_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.10E-86"
                     /label="arzN_oMT.1"
                     /locus_tag="arzN"
                     /protein_end="1225"
                     /protein_start="1004"
                     /score="282.9"
                     /tool="antismash"
                     /translation="KYLTFAPFPKIVPGFSWLLTLAEPQKYQKYMQATLDAQKEMRDVL
                     FAKVDFSSSTKVLDFGCGYGSDLIDLAEKYSHLKLYGYTISSEQAKIATKKIHERHLQE
                     RVTVFNRDSSKDEFTEQYDLEFGFEVAHHIKDKSALFSNLGRSLKDEGFLVLADFISNA
                     TFPIEHHETSSYFITKEEWVEQLSHNHLKIIDCIDVSQEIANFLYDPNFEENLEKLYQ"
     CDS_motif       31412..31510
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0010"
                     /evalue="4.30E-17"
                     /label="PKSI-KR_m1"
                     /locus_tag="arzN"
                     /protein_end="1570"
                     /protein_start="1537"
                     /score="54.6"
                     /tool="antismash"
                     /translation="SYLVTGGLGALGLKVAHWMVKQGAKHLILISRR"
     aSDomain        31412..31942
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzN_PKS_KR.1"
                     /evalue="1.90E-69"
                     /label="arzN_PKS_KR.1"
                     /locus_tag="arzN"
                     /protein_end="1714"
                     /protein_start="1537"
                     /score="225.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="SYLVTGGLGALGLKVAHWMVKQGAKHLILISRREVSDVDQTSVSQ
                     LEQAGAQVLVVKSDVSDQMDLARTLQEIKSSMPPLRGIVHAAGILDDGVLLQQNWERFA
                     SVMAPKVEGAWNLHSLTQNLPLDFFVCFSSVAAVLGSPGQGNYAAANAFLDALAYYRRS
                     LGLSALSINWGPWT"
     CDS_motif       31736..31765
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0011"
                     /evalue="1.90E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="arzN"
                     /protein_end="1655"
                     /protein_start="1645"
                     /score="11.6"
                     /tool="antismash"
                     /translation="PKVEGAWNLH"
     CDS_motif       31787..31897
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzN_0012"
                     /evalue="4.60E-24"
                     /label="PKSI-KR_m4"
                     /locus_tag="arzN"
                     /protein_end="1699"
                     /protein_start="1662"
                     /score="77.1"
                     /tool="antismash"
                     /translation="LDFFVCFSSVAAVLGSPGQGNYAAANAFLDALAYYRR"
     aSDomain        32222..32476
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzN_PKS_PP.1"
                     /evalue="9.40E-18"
                     /label="arzN_PKS_PP.1"
                     /locus_tag="arzN"
                     /protein_end="1892"
                     /protein_start="1807"
                     /score="56.3"
                     /tool="antismash"
                     /translation="LKAANPSDRLELLVTYLQTRVAKILGLGASLQPEPDDSLNELGLD
                     SLMGIELKNRITTELGVNIPLQKFTEGISIKQLALAVLEE"
     gene            32551..36813
                     /gene="arzO"
     CDS             32551..36813
                     /NRPS_PKS="Domain: Heterocyclization (74-372). E-value:
                     4.4e-110. Score: 359.7. Matches aSDomain:
                     nrpspksdomains_arzO_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (543-942). E-value: 5.8e-98.
                     Score: 320.1. Matches aSDomain:
                     nrpspksdomains_arzO_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1317-1385). E-value: 2.4e-18.
                     Score: 58.1. Matches aSDomain: nrpspksdomains_arzO_PCP.1"
                     /codon_start=1
                     /gene="arzO"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /product="ArzO - NRPS (Cy, A, Ox, PCP)"
                     /protein_id="DAB41917.1"
                     /sec_met_domain="Condensation (E-value: 1.9e-50, bitscore:
                     161.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2e-110, bitscore:
                     359.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PF00881 (E-value: 5.8e-19, bitscore: 58.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.9e-14, bitscore:
                     42.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLNELLTELSQQNMELRAEGDQVRVRAAKGTLTPEIRDSIAEHK
                     TQLLDLLQKSNMRADNTSLPSVVPAPDKRYDPFPLTDIQYAYWIGRNEIYELGNVVTHA
                     YLELDCQDLNLERLNLAWQKVIERHEMLRAVVLPDGQQQILEQVPPYQISVLDLCGQSA
                     ESIDFTFETLRQRMSHQVRLADQWPLFEIQAVHLDNQHFQLHLSFDVLMIDMGSLLCLF
                     REWSQLYQNPKLELPLLELSFRDYVLAEKRLVETQLYQRSQDYWFNRLDTLPPAPELPL
                     LKSPSSCHQPRFHRRTFRLDPELWQQLKKRAISTNLTSSGVLLAAFAEVLTAWSKYPQF
                     TINITLFNRLPLHPQVNQIAGDFTSLTLLQVDNSTVNESFASRAVRLQKQLWQDLDYHH
                     VSGVHILRELARRQGNSRRSIMPIVFTSALAVDSLDRNNSGLSQFGEMVYGVSQTPQVL
                     LDHQVIEQDQGLIFNWDAVENLFPPGMLEDMFNTYCHFLARLATDESVWYSTTRQLIPP
                     EQLSQRDTINATEAPLSNEMLHTLFISQVERCSDHCAVISPQRTLTYLELSKLARQVGY
                     KLRQLGASPNNLVAVVMEKGWEQVVGVLGILMSGAAYLPIDPELPTERQKYLLDQGEVK
                     IALTQSHLNEKLEWSAGIYRLNVDNQKLTDENLPIFESVQSPEDLAYVVYTSGSTGVPK
                     GVMIDHQGAVNTILDINQRFQVGEQDRVLALSALNFDLSVYDIFGILAAGGTIVIPEAA
                     ATKDPSHWMELIARHQVTLWNSVPALMQMFVEYVRLHPNKVSQSLRLALLSGDWLPLNL
                     PTQIKSLWPNALVVSLGGATEASIWSIFYPIEKVSSEWKSIPYGRPMTNQYFYVLNEAL
                     EPCPVWVTGQLYIGGTGLAKGYWKDDLKTHSSFIIHPRTRKRLYKTGDLGRYLPDGNIE
                     FLGRKDFQVKINGYRIELGEIETILEQHPLVNHAVVTAAGETRENKQLVAYIVSNSFSS
                     SQEQLAASNQIAEAYRPSQSNKVLTDPVKRLEFKLKQPGLRLLETNRFSVELIKPQFDE
                     VLIQTYVKRQSYRHFLDTPIPFAQFSELLSCLLQIKLNNAPLPKYRYASAGNLYPVQTY
                     LYVKPGRVEGLEAGTYYYHPADHRLVLLSPEAVIERHIHSEINQPIFDESAFSLFLIGQ
                     LSAITPMYGELARDFCLLEAGYISQLLMSVAPASQIGLCPVGAQDFAAIQNVFEIDSNH
                     ILLHSFFGGRIELEKTQQALQPKATPSVATIADELRSFLQGKVPDYMVPAIYVLLDTLP
                     LTVNGKVDRRALPTPALVQSKLNVVDAPPQTEVERTLANIVQAVLQVETVGIHSNFFEL
                     GANSVHMIQIYNKLKEALGIDVAIVEMFKHPTINFLAKYLSQEIDESSSLEQIHDRVFK
                     QKEAIKQQKRLMEKRKNG"
     aSDomain        32773..33666
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzO_Heterocyclization.1"
                     /evalue="4.40E-110"
                     /label="arzO_Heterocyclization.1"
                     /locus_tag="arzO"
                     /protein_end="372"
                     /protein_start="74"
                     /score="359.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DVLMIDM"
                     /tool="antismash"
                     /translation="YDPFPLTDIQYAYWIGRNEIYELGNVVTHAYLELDCQDLNLERLN
                     LAWQKVIERHEMLRAVVLPDGQQQILEQVPPYQISVLDLCGQSAESIDFTFETLRQRMS
                     HQVRLADQWPLFEIQAVHLDNQHFQLHLSFDVLMIDMGSLLCLFREWSQLYQNPKLELP
                     LLELSFRDYVLAEKRLVETQLYQRSQDYWFNRLDTLPPAPELPLLKSPSSCHQPRFHRR
                     TFRLDPELWQQLKKRAISTNLTSSGVLLAAFAEVLTAWSKYPQFTINITLFNRLPLHPQ
                     VNQIAGDFTSLTLLQVD"
     aSModule        32773..36705
                     /complete
                     /domains="nrpspksdomains_arzO_Heterocyclization.1"
                     /domains="nrpspksdomains_arzO_AMP-binding.1"
                     /domains="nrpspksdomains_arzO_PCP.1"
                     /locus_tags="arzO"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       32923..32976
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0001"
                     /evalue="1.40E-09"
                     /label="Cy2"
                     /locus_tag="arzO"
                     /protein_end="142"
                     /protein_start="124"
                     /score="30.0"
                     /tool="antismash"
                     /translation="VIERHEMLRAVVLPDGQQ"
     CDS_motif       33496..33555
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0002"
                     /evalue="1.10E-07"
                     /label="Cy4"
                     /locus_tag="arzO"
                     /protein_end="335"
                     /protein_start="315"
                     /score="24.5"
                     /tool="antismash"
                     /translation="NLTSSGVLLAAFAEVLTAWS"
     CDS_motif       33568..33606
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0003"
                     /evalue="2.70E-04"
                     /label="afterCy4"
                     /locus_tag="arzO"
                     /protein_end="352"
                     /protein_start="339"
                     /score="13.6"
                     /tool="antismash"
                     /translation="FTINITLFNRLPL"
     CDS_motif       33607..33666
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0004"
                     /evalue="9.00E-08"
                     /label="Cy5"
                     /locus_tag="arzO"
                     /protein_end="372"
                     /protein_start="352"
                     /score="24.3"
                     /tool="antismash"
                     /translation="HPQVNQIAGDFTSLTLLQVD"
     CDS_motif       33811..33837
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0005"
                     /evalue="1.10E-02"
                     /label="Cy6"
                     /locus_tag="arzO"
                     /protein_end="429"
                     /protein_start="420"
                     /score="8.8"
                     /tool="antismash"
                     /translation="MPIVFTSAL"
     CDS_motif       33901..33975
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0006"
                     /evalue="1.10E-06"
                     /label="Cy7"
                     /locus_tag="arzO"
                     /protein_end="475"
                     /protein_start="450"
                     /score="21.5"
                     /tool="antismash"
                     /translation="VSQTPQVLLDHQVIEQDQGLIFNWD"
     CDS_motif       33991..34020
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0007"
                     /evalue="9.30E-03"
                     /label="afterCy7"
                     /locus_tag="arzO"
                     /protein_end="490"
                     /protein_start="480"
                     /score="9.4"
                     /tool="antismash"
                     /translation="FPPGMLEDMF"
     aSDomain        34180..35376
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzO_AMP-binding.1"
                     /evalue="5.80E-98"
                     /label="arzO_AMP-binding.1"
                     /locus_tag="arzO"
                     /protein_end="942"
                     /protein_start="543"
                     /score="320.1"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="SQVERCSDHCAVISPQRTLTYLELSKLARQVGYKLRQLGASPNNL
                     VAVVMEKGWEQVVGVLGILMSGAAYLPIDPELPTERQKYLLDQGEVKIALTQSHLNEKL
                     EWSAGIYRLNVDNQKLTDENLPIFESVQSPEDLAYVVYTSGSTGVPKGVMIDHQGAVNT
                     ILDINQRFQVGEQDRVLALSALNFDLSVYDIFGILAAGGTIVIPEAAATKDPSHWMELI
                     ARHQVTLWNSVPALMQMFVEYVRLHPNKVSQSLRLALLSGDWLPLNLPTQIKSLWPNAL
                     VVSLGGATEASIWSIFYPIEKVSSEWKSIPYGRPMTNQYFYVLNEALEPCPVWVTGQLY
                     IGGTGLAKGYWKDDLKTHSSFIIHPRTRKRLYKTGDLGRYLPDGNIEFLGRKDFQVKIN
                     "
     CDS_motif       34360..34401
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0008"
                     /evalue="8.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="arzO"
                     /protein_end="617"
                     /protein_start="603"
                     /score="12.9"
                     /tool="antismash"
                     /translation="LGILMSGAAYLPID"
     CDS_motif       34591..34650
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0009"
                     /evalue="1.90E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="arzO"
                     /protein_end="700"
                     /protein_start="680"
                     /score="32.5"
                     /tool="antismash"
                     /translation="AYVVYTSGSTGVPKGVMIDH"
     CDS_motif       34762..34794
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0010"
                     /evalue="1.50E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="arzO"
                     /protein_end="748"
                     /protein_start="737"
                     /score="0.1"
                     /tool="antismash"
                     /translation="FGILAAGGTIV"
     CDS_motif       35173..35262
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0011"
                     /evalue="3.20E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="arzO"
                     /protein_end="904"
                     /protein_start="874"
                     /score="32.3"
                     /tool="antismash"
                     /translation="PVWVTGQLYIGGTGLAKGYWKDDLKTHSSF"
     CDS_motif       35341..35406
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzO_0012"
                     /evalue="2.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="arzO"
                     /protein_end="952"
                     /protein_start="930"
                     /score="38.8"
                     /tool="antismash"
                     /translation="FLGRKDFQVKINGYRIELGEIE"
     aSDomain        36502..36705
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzO_PCP.1"
                     /evalue="2.40E-18"
                     /label="arzO_PCP.1"
                     /locus_tag="arzO"
                     /protein_end="1385"
                     /protein_start="1317"
                     /score="58.1"
                     /tool="antismash"
                     /translation="ERTLANIVQAVLQVETVGIHSNFFELGANSVHMIQIYNKLKEALG
                     IDVAIVEMFKHPTINFLAKYLSQ"
     gene            36806..41956
                     /gene="arzP"
     CDS             36806..41956
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (12-439). E-value:
                     1.2e-165. Score: 543.4. Matches aSDomain:
                     nrpspksdomains_arzP_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (543-838). E-value: 4e-115.
                     Score: 376.2. Matches aSDomain:
                     nrpspksdomains_arzP_PKS_AT.1"
                     /NRPS_PKS="Domain: cMT (1070-1276). E-value: 1.3e-81.
                     Score: 266.0. Matches aSDomain: nrpspksdomains_arzP_cMT.1"
                     /NRPS_PKS="Domain: PKS_PP (1323-1402). E-value: 6.9e-13.
                     Score: 40.8. Matches aSDomain:
                     nrpspksdomains_arzP_PKS_PP.1"
                     /codon_start=1
                     /gene="arzP"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /product="ArzP - PKS (KS, AT, OMT, ACP, TE)"
                     /protein_id="DAB41918.1"
                     /sec_met_domain="mod_KS (E-value: 4.3e-136, bitscore:
                     444.1, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 1.5e-176, bitscore:
                     577.5, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 1.9e-160, bitscore:
                     524.4, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 7.2e-76, bitscore:
                     245.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 3.3e-166, bitscore:
                     543.4, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 7.5e-130, bitscore:
                     423.5, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 1.6e-64, bitscore: 208.2,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.1e-115, bitscore:
                     376.2, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.8e-10, bitscore:
                     30.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 3.9e-25, bitscore:
                     79.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSEVNSDSIESIAIIGMSGRFPGAKNLNEFWQNLRDGKESISFF
                     SEQELIDNGIDPVMVSHSNYVKAGAILEDVDLFDASFFSFSNREATFMDPQHRFFMECA
                     WEALESAGYTSETYDGKIGVYAGSSMNSYLLSNLHQHFDPTIGTDILQALIGNDKDYLT
                     TRLSYKLNLKGPSITVQTACSTSLVAVCQGCQSLLNYQCDMALAGGVSIRLPLKAGYLF
                     EKGSILSPDGHCRAFDARAQGTIFGSGVGVVVLKRLADAINDRDDIHAVIKGCAINNDG
                     ALKVGYTAPGLDGQAEVIGMAQVLAGVEPETITYIEAHGTGTSIGDPIEVAALTQVFRA
                     STKKKGFCAIGSVKTNIGHLEAAAGVASLIKTVLALKHKLIPPSINFVVPNPQIDFAKS
                     PFYVNTKLAEWQTNGFPRRAGVSSFGIGGTNAHVVLEEAPRPKLKHIQQERPIHLLCLS
                     AKSEKALRELAQQFGSHLAANPSAQLGDICFTANAGRSHFSHRLVVVGESKEQMHDKLN
                     AFTASRETSEVLSMYVLSSNQQKIAFLFTGQGSQYVGMGRQLYDTQPIFREILNRCDKI
                     LYPYLKQSLLSVLYPEPSTISPLDETAFTQPALFALEYALTELLQSWGIKPSVVMGHSL
                     GEYVAACVAGVFSLEDGLKLVAERSRLMQSLPQDGAMAVVFTSKARVVAAIQTYAREVV
                     IASVNGPQNIVISGKREAVNEVIAVLQAEEVQTRILKVSHAFHSPLMEPMLATFEQIAK
                     QITYSSPRLDVISNVTGEIAKREIATPQYWCRHIRQPVKFAASMETLYQQGYEIFLEIG
                     PKPTLLGMGRQCLPEGSRAWLPSLRQGHSDWQQLLQSLGELYVRGAKVDWFGFDQGYPR
                     YRVQLPTYPWQRSCHWLEEAHEERLDKKLEASHLWETAVSASRYQAHRGPLDLALHTYS
                     AKQEFLERLTTAYITEVLFNLGAYIQAGERHSVDDLLHQFKISSTYRKLLSLWLEKMTN
                     AGLLKQQEEEIFVCDHPLACSQMDSLFSEVREIFTDAPFLLDYLQYCGSRLADILASKQ
                     TSLETLFLGGSLDTSENFYGKWAVARYFNDIIRSITESVVKALSPGKQLRILEIGAGTG
                     ATTASVLSVLPPEKTIYYFTDVSDFLFTRAREKFKAYPFVHYGLLDIERDPRNFGYTYQ
                     SFDVVIATHVLHTTSNLGETLEHVLSLLAPGGLLLLNEFTCHTLWLEMFMGLLGGRQQF
                     DDPFRQENSLLSEKQWEEALRDCGFEKVVAFPEPGSLAEILGQHILVAQVPVHVTYPQD
                     CCISAIADQSLISKPGGKFSTSYPVVQTPESSLTRKKLLALPLGKRQDLLRSYLGEQVA
                     KALGISTSQLDTEHSLKDIGLDSLMAIVIKNQVEMDLGLVMPIANFLQDISLDQLTMQA
                     LEQLTVISFTPEASNTAVLETALKHFGSPSKSLVEIQPTGSKPPFICVHPGGLDVSGYA
                     NLARHLTNEQPVYVLQPPELDNYRSLNEELPLFTTIEDVAAQCVKALCGLQPQGPYLLG
                     GWSLGGCVAFEIAQQLHKQGHKVALLALLDVADIFHSPLDNDYALVSGFASYLGARRDK
                     ELLISYNDLQGLDLDEQLNQVLKQAIMMGVVPWNTGISEIRNFFQIYKTGTQTSLRRLQ
                     NYRPQIYPNQITLFQASEALGGLSEVVREPIFNWGDWSKFSTKPPELHIVPGNHYTILV
                     EPHVQVLAQKLKHCLDQVK"
     aSDomain        36842..38122
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzP_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.20E-165"
                     /label="arzP_PKS_KS.1"
                     /locus_tag="arzP"
                     /protein_end="439"
                     /protein_start="12"
                     /score="543.4"
                     /tool="antismash"
                     /translation="IAIIGMSGRFPGAKNLNEFWQNLRDGKESISFFSEQELIDNGIDP
                     VMVSHSNYVKAGAILEDVDLFDASFFSFSNREATFMDPQHRFFMECAWEALESAGYTSE
                     TYDGKIGVYAGSSMNSYLLSNLHQHFDPTIGTDILQALIGNDKDYLTTRLSYKLNLKGP
                     SITVQTACSTSLVAVCQGCQSLLNYQCDMALAGGVSIRLPLKAGYLFEKGSILSPDGHC
                     RAFDARAQGTIFGSGVGVVVLKRLADAINDRDDIHAVIKGCAINNDGALKVGYTAPGLD
                     GQAEVIGMAQVLAGVEPETITYIEAHGTGTSIGDPIEVAALTQVFRASTKKKGFCAIGS
                     VKTNIGHLEAAAGVASLIKTVLALKHKLIPPSINFVVPNPQIDFAKSPFYVNTKLAEWQ
                     TNGFPRRAGVSSFGIGGTNAHVVLEEAP"
     aSModule        36842..41011
                     /complete
                     /domains="nrpspksdomains_arzP_PKS_KS.1"
                     /domains="nrpspksdomains_arzP_PKS_AT.1"
                     /domains="nrpspksdomains_arzP_cMT.1"
                     /domains="nrpspksdomains_arzP_PKS_PP.1"
                     /locus_tags="arzP"
                     /monomer_pairings="mal -> Me-mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       37325..37372
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzP_0001"
                     /evalue="5.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="arzP"
                     /protein_end="189"
                     /protein_start="173"
                     /score="18.5"
                     /tool="antismash"
                     /translation="GPSITVQTACSTSLVA"
     CDS_motif       37748..37795
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzP_0002"
                     /evalue="1.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="arzP"
                     /protein_end="330"
                     /protein_start="314"
                     /score="13.9"
                     /tool="antismash"
                     /translation="YIEAHGTGTSIGDPIE"
     CDS_motif       37856..37900
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzP_0003"
                     /evalue="2.90E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="arzP"
                     /protein_end="365"
                     /protein_start="350"
                     /score="13.1"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAAAG"
     aSDomain        38435..39319
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzP_PKS_AT.1"
                     /evalue="4.00E-115"
                     /label="arzP_PKS_AT.1"
                     /locus_tag="arzP"
                     /protein_end="838"
                     /protein_start="543"
                     /score="376.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYVGMGRQLYDTQPIFREILNRCDKILYPYLKQSLLSV
                     LYPEPSTISPLDETAFTQPALFALEYALTELLQSWGIKPSVVMGHSLGEYVAACVAGVF
                     SLEDGLKLVAERSRLMQSLPQDGAMAVVFTSKARVVAAIQTYAREVVIASVNGPQNIVI
                     SGKREAVNEVIAVLQAEEVQTRILKVSHAFHSPLMEPMLATFEQIAKQITYSSPRLDVI
                     SNVTGEIAKREIATPQYWCRHIRQPVKFAASMETLYQQGYEIFLEIGPKPTLLGMGRQC
                     LPEGSRAWLPSLRQ"
     CDS_motif       38438..38485
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzP_0004"
                     /evalue="1.10E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="arzP"
                     /protein_end="560"
                     /protein_start="544"
                     /score="20.9"
                     /tool="antismash"
                     /translation="FTGQGSQYVGMGRQLY"
     CDS_motif       38621..38656
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzP_0005"
                     /evalue="9.40E-04"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="arzP"
                     /protein_end="617"
                     /protein_start="605"
                     /score="12.0"
                     /tool="antismash"
                     /translation="QPALFALEYALT"
     CDS_motif       38675..38797
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzP_0006"
                     /evalue="2.00E-28"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="arzP"
                     /protein_end="664"
                     /protein_start="623"
                     /score="90.9"
                     /tool="antismash"
                     /translation="GIKPSVVMGHSLGEYVAACVAGVFSLEDGLKLVAERSRLMQ"
     CDS_motif       38891..38929
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzP_0007"
                     /evalue="1.10E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="arzP"
                     /protein_end="708"
                     /protein_start="695"
                     /score="12.3"
                     /tool="antismash"
                     /translation="ASVNGPQNIVISG"
     CDS_motif       39149..39184
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzP_0008"
                     /evalue="1.70E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="arzP"
                     /protein_end="793"
                     /protein_start="781"
                     /score="18.1"
                     /tool="antismash"
                     /translation="YWCRHIRQPVKF"
     aSDomain        40016..40633
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzP_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="1.30E-81"
                     /label="arzP_cMT.1"
                     /locus_tag="arzP"
                     /protein_end="1276"
                     /protein_start="1070"
                     /score="266.0"
                     /tool="antismash"
                     /translation="AVARYFNDIIRSITESVVKALSPGKQLRILEIGAGTGATTASVLS
                     VLPPEKTIYYFTDVSDFLFTRAREKFKAYPFVHYGLLDIERDPRNFGYTYQSFDVVIAT
                     HVLHTTSNLGETLEHVLSLLAPGGLLLLNEFTCHTLWLEMFMGLLGGRQQFDDPFRQEN
                     SLLSEKQWEEALRDCGFEKVVAFPEPGSLAEILGQHILVAQVP"
     aSDomain        40775..41011
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_arzP_PKS_PP.1"
                     /evalue="6.90E-13"
                     /label="arzP_PKS_PP.1"
                     /locus_tag="arzP"
                     /protein_end="1402"
                     /protein_start="1323"
                     /score="40.8"
                     /tool="antismash"
                     /translation="ALPLGKRQDLLRSYLGEQVAKALGISTSQLDTEHSLKDIGLDSLM
                     AIVIKNQVEMDLGLVMPIANFLQDISLDQLTMQA"
     CDS_motif       41339..41413
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_arzP_0009"
                     /evalue="8.40E-15"
                     /label="NRPS-te1"
                     /locus_tag="arzP"
                     /protein_end="1536"
                     /protein_start="1511"
                     /score="47.0"
                     /tool="antismash"
                     /translation="QPQGPYLLGGWSLGGCVAFEIAQQL"
ORIGIN
        1 atgaaacttc ctaatacact caaaactcct gctcttctcc aaaagcttca gtgggttatt
       61 gaccctgttg gctatatgga acaagcagct cagcaacacc ctgacctgtt tacagctgag
      121 attgttggat ttggagatac ggttgtattt ctatatgatc cccaagctat tcaagaagtt
      181 ttaaccaatg ataggaagaa atttgtagct ttaagtcagg ggaacagatt tttacaacct
      241 attgttgggg attattcaat tgctatgctg gagggagaac gccacagaaa gcgacgacag
      301 ctcttgctac ctccgcttca tggggagcga ttgcaagcct acagtcagct catttgtaat
      361 ctgaccgaca aaatctttag tcagctaccc caaaatcagt ccttctctgc ttgcgttgta
      421 acgcagcaga tttccgtaca agtcatctta gaggtaattt ttggattgtc tcagggaaaa
      481 aagcgctacc aagaacttga gcatttgcta atgttggctg cggatatatt tcaatctcat
      541 ctagcaccta ttgtcctata tttttccttt ctgcaaaaag atttaggatt ttggagtcct
      601 tggggcaagt ttgtacgcat acagcagcaa attgatgaat tgatttatgc agagattgca
      661 gaacgccgag aacaattcaa ccctcattgc ccttcggata tgccacgtga tcgcattgat
      721 attctctcgt tgttgctgtc agctcgggac gaaatgggga actcaataac agatttagaa
      781 gtgcgttgtg aactgatgac actgcttcta gctggacaag aatcaacagc atcagcaatg
      841 gcttggggat tgtattgggt tcaccagttg ccacatgtgc atgaaaaact gctttgcgaa
      901 ctgaatagtc ttgggggttc accagacccc atgagtcttg tccgactacc ttatctcaca
      961 gctgtgtgtc atgaaacctt acggattgct cctgctgtga tggtcacgtt tcctaggatc
     1021 gtgcaagaat ccgttgaact gctgggacat agattagagc caggaatggt tgtactaggt
     1081 tgcgtttatt tgactcacca gcgtgaagat ttatatccac aacctaagca gtttaagcca
     1141 gagcgttttc tagaacgtca attttctcct tacgaattta tgccctttgg tggtggcgct
     1201 cgtggctgta ttggtggctc actagctcag tttgaactaa agcttgtctt agctactatc
     1261 ttatcaaaat atcaattaga attagcagat catcgtccag aacagcttcg acgtcgagga
     1321 attacccttg ctcctacaaa tggaattaaa atgaaacgta ccaagatata gatcggcaac
     1381 aacgttcatc taagtcatgt caatgcttta agctgaagca ggcactctat tagatgtact
     1441 gtatttagat agtcttacac gaatgaatct aaatggacaa aagatttcgt caccagtaac
     1501 agagttgaga tagaacaagt acttcaaaaa tctcattgtt cagaaacacc aatttaactt
     1561 ttaattgaat tcaggaatgg aatttcacta gttttgcaag atctagatgc taaaagccta
     1621 gacattcaca tagaatttgc gaatgcaatg gtgaaactga aggttgttca gtatctcaat
     1681 tgattcaaaa gcaagaggac agcatgctaa aaaacttgtg atatacatat gaatttagct
     1741 caacaattac aagcaatccc aaccgagcgt aatgtctacc actatcaata tgtttgaaat
     1801 gggagttcag gcataagttc tcaaacgagg aacattatat gctcagagag caaacaagct
     1861 ctatgaactc tataatacca agttgctaaa gctagtcttt ggaatcaagt tcactattaa
     1921 actgacttac gaacaaataa ttgcgatcaa agacaacttg gtataagacg atgagacgta
     1981 aactcatagt tgagtaacag tcatgactac aacccttatc aatgacggaa aacctcaaag
     2041 caatagtaaa actcagaaac tgggttcaag ttggtttcgc agtcttaaag ccattattgc
     2101 attaaccatt tatggtctct acgagttagt ctttgtacat aaattctttt tgcacacttt
     2161 ttttcgctca tttgtttctg acgttccgcc tccgatttcg ttaaagattg gttattggaa
     2221 taagcttcaa ttcaaagcta ttctcttgat gcgttacttg ttaaaaaacc aattttgggg
     2281 gcagcagtgg ttaaagcgtg tccatcgtag tattctagag aacctcaaca aacaggacat
     2341 tgatttttca aaacttaaga tgccaatccc tacggtagaa ccggggaaaa tttccgctca
     2401 agagttttgg aaaacctatg tgagaacgaa tacaccagtg attatcaaag gtggttcaaa
     2461 acacaccttt gcctatcaaa actggacaat ggaaatgttt cgggaacgct gcggcgactt
     2521 gaaagtcaga attattaata tgagcaaaaa cgaacatagt gatagtagat tcaaatatga
     2581 aattggaacg atcaaagatg taatcgatag taaaggaact gaaaacaagc tctatcttgt
     2641 agtttgtgca aatgtcttct ctatttatcc agacttattg gatgaaatag gctgtttaga
     2701 ttttagagaa tacgtaggcg gtaactctac tttttttgct ggtgcacagt tgtttttagg
     2761 agtacattct ttcaccggta gccatactca ttgtgaacgt ggtaatagtc tgtttttcca
     2821 aattggtggt aggaaaaagt ggacgcttgt gcatccggat tatctatggc tgatgtatcc
     2881 aatgctcgaa catttcttta tatcttgtgg ttcttttgtt aaaaacgatt acgatcaagc
     2941 ctatcttgag caatatgcac cgctccagaa atattgtccc aaatatgaag ccgtcttaga
     3001 gccgggagat gttcttttca atccaggatg gcattggcat gccgttgaga acctcacaga
     3061 agaaactatt ggtgttggaa ctcgttggcc tgaggtaaga caaaaacgtg caaatcaatt
     3121 ttttgacttt atgcagttaa tttcaccaaa ggtgtggaat attaaatttg gtttgatagc
     3181 gaaagacccc aatgaattag taggaggtgt attggttgaa ctagtagaaa atgtgttcaa
     3241 aaaagatact gaacttgtta tgttgggtaa agaggatgga gtaatagccc gggaatttga
     3301 taaatggcct aaggagtatc aattttagag cctgttcctg ttgcatattc tgtccaacag
     3361 atatgtatgc caatcaatcg tctagtaaga tgatgagact tgcacttgca gttgagtaac
     3421 aaccatgact acaaccctta gcaataacgg aagatctcaa agcaatagga caacgaacag
     3481 accaagtcca agtttgttcc gtactctaaa agtcatcgtt atgttgacta tctatggtat
     3541 ctatgaagta gtctttgtac ataaattctt tttgcacacc tttttccgtt catcgatttc
     3601 taatgttctg cctccaattt cattgaagat tggttattgg aacaagcttc aattcaaagc
     3661 tattctcttg atgcgttact tgttaaaaga ccaattttgg ggacagcagt ggttaaagcg
     3721 tgtccatcgt agtattctag agaacctcaa caaacaggac attgattttt caaaacttaa
     3781 gatgccaatc cctacggtag aaccggggaa aatttccgct caagagtttt ggaaaaccta
     3841 tgtgagaacg aatacgccag tgattatcaa aggtggtgca aaacacacct ttgcctatca
     3901 aaactggaca atggaaatgt ttcgggagcg ctttggtgac tttaaagtta atattgctaa
     3961 tcaaagcaaa aatgacgaac ttaatgttgg tacatttaaa gatgtcatcg atagcagtga
     4021 aagtgaggac aaactctata ttacgttcta tgcagacatc ttttctgctt atccagagtt
     4081 agtggatgaa gtaggctgtt tagaatttag agaatatatg ggtggcaacg ctgctttgtt
     4141 cgctggagca cagttgtttt taggagcaaa atcttcaacg gggagtggtg ctcattgtgc
     4201 tgatggtaat aatttatttt ttcaaattca tggcaagaaa aagtggacat ttgtgcatcc
     4261 ggattatcta tggctgatgt atccaatgct caatcgtttc tttctttttt gtggttcctt
     4321 tcttaaaaac gagtacgacc cagtgtacct cgagcaatac gcgccactgc agaaatattg
     4381 tcccaaatgt gaagccgtct tagagccggg agatattctc cttaatccac catggcaatg
     4441 gcatgccatt aacaatctca ctgagaaaac catcgccgtt gcaactcgct ggtctttagt
     4501 caaacaaaaa cgtgcgaata cattttttga tttcatgcag ttattctcac cacatatatg
     4561 gcgtatgcga tttgatctgc ttaccaaaga tcctaatgaa ataggaggtg tattggatga
     4621 aagaacagat aacttgtttg agaaaaaaga tgattttgtt gttatgggga aaggggacgc
     4681 aatgacaacc tggcagtttg ataaatggcc caagaagtat cagttttaga gtctgcctta
     4741 cggcaaacct atgtaacatt tatacccatc aaataattta gtcatacgaa gaaatacaaa
     4801 ctcacaatta agtaacagct atgactacaa ctctcatcaa agaaaggaaa tctcagaacg
     4861 ataaaaagat gaagaagctg agcccaagtt ggtttcgcgc cctcatagct atagttgtat
     4921 tggctatcta tggtatctat gaggtagtct ttgtacataa attctttttg cacacctttt
     4981 tccgctcatc aatttctaat gttccacctc cgattgcatt gaagattggt tattggaata
     5041 agcttcaatt caaagctatt ctcttaatac gttatttctt gaaagaccaa ttttggggac
     5101 aacagtggtt aaagcgtgtc caccgcagta ttctagagaa tctcaacaaa caggacatcg
     5161 atttttcaaa actcaagatg ccgatcccaa ccgtagaact agagcaaatt tccgctcaag
     5221 agttttggaa aacttatgtg agaacgaata caccagtgat tatcaaaggt ggtgcaaaac
     5281 atacctttgc ctaccaaaat tggacactag aaatgtttcg ggaacgcttt ggtgacttca
     5341 ggactgatac cgttaatctg agcagtagaa atgaatacaa cggtggcacg ttacacaatg
     5401 ttagtacctt caaagatgtg atcgacagca gggaaagtaa tgaaaaactt tatatcgttt
     5461 tctgcacaga tatcttctcc gcttacccgg agttagtaaa tgaactgagc tgtttagatt
     5521 tcagagcaca tatgggtggc aacgctgcct tgttcgctgg agcacagttg tttttaggag
     5581 caaagccttt aactggtact gatgctcatt gtgctgatgg taataacctg tttttccaaa
     5641 tttgcggtaa gaaaaagtgg acatttgtgc atccagatta tctatggcta atgtatccaa
     5701 tgcttgatcg tttctttcta ttttgtgctt cctttgttaa aagagattac gagcaagtgt
     5761 atctcgatca atacgcacca ctgcaaaaat attgtcccaa atacgaagcc gttttagaac
     5821 cgggagatgt tcttcttaat ccaccttggc aatggcatgc tattgacaac cttactggtg
     5881 acaacattgc cgttgccact cgatggtctt tagtaagaca gaagcgtgcg aatacatttt
     5941 ttgatttcat gcagttgttt tcaccaaaaa tctggcgtat tcgatttgat gtggtgacaa
     6001 gagatccgga tgcagtaagt atattggata aaagaacaac agatgattta gttaagaata
     6061 aatcagtcaa gagtgaagag gattttgttg ggttgggaaa cgaggatgga gtaacagctt
     6121 gggattttga taaatggcct aaggaatatc agttttagag ccttgtttgg ttgcacattg
     6181 tctctatcga tggcatgaca agtaatttaa atagtacttt cacccgtatc ttgcatctat
     6241 ccgtgtcaac tattagcagt gatcgctagc aacaaattaa agaagcacat tttgctggaa
     6301 attaccttta ctgtatcagg gttctaaaat ttgcatctta ggagcctatt aacttgtcgt
     6361 ttaactgttc aatctcaggt acaaaagtca ggtttaatgt cttatgacat cacgttttcc
     6421 atttccatcc tacccaaata gctggtactg tgtcgctcac agtgacgaac tgtcttctgg
     6481 tatggttaaa ccacttcact attttggaaa ggatctagtg ctgtttcgta cagaagatgg
     6541 taaagctcat gttcttgatg cttattgtcc acacttagga gcccacctag gttacggagg
     6601 gcaggttaag ggccacacca tccgatgccc gtttcatggt ttgtgcttcg acagccatgg
     6661 ttactgcacg cataccacct atgcccaaaa actaaattct aatatccgtt tttggttagt
     6721 tcatgaaact aatgggctaa ttttggttta ttatgatgct caaggaaaat taccccactg
     6781 ggagataccg acattaccag aatataattc aaaagaatgg actcaattcc agccagttgg
     6841 aagatggaag attcgtgctc atgtccagga tatgggtgaa aatattcctg atatttatca
     6901 tgctagcgct ttacattcaa cattgatatt ggatcatact gtatttgttg aaggtccatt
     6961 ctggagggag ttgtttaatg taaagcctgt gaacaatcaa aaggctcctt ttctaaatat
     7021 agaggtagtt ggtaactacg aagtaactag ctatggttta ggctacacgg tttctaaaca
     7081 aaggcttcac cacaaggcaa tgttggagct aaggttaatc cttcggtata cagtcacacc
     7141 tattgatact gagtatgtcg atcttcgctt cgatattagt gtcaagaagt tcattaattc
     7201 agctataact cttgccttta caaaaccagt gttcaaagca ctaaagacgg aattagagaa
     7261 agatctcata atttgggaga acaaaattta ctactctcgt cctctctttt tggaagggga
     7321 ggaagagatt atagaatatc ggaattgggc taaccagttc tactcagaga tacctgcatt
     7381 aaatactaaa actcttgctt gagaacaact aagtagtgtg ggtatgccca ggatgttctc
     7441 atatcccccc tatcaatgtg tttgaaatgg gagtttaggc ataagttttt aaacgaggaa
     7501 cattatatgc tcaaagagca aacaaacttt acaaactcta taagacgatg agacgtaaac
     7561 tcacagttga gtaacagcca tgactacaac ccttatcaat gatggaaaat cccaaagtga
     7621 tggaacaacg aagaaagtta atctaaactg gtttcgtatt ctcaaagcta tcattatatt
     7681 gactatctat agtatctacg agatagtctt tgtacataag ttctttttac acacctttct
     7741 ccgctcatca atttctgatg ttccacctcc gatttcgtta aagattggtt attggaataa
     7801 gcttcaattc aaagctattc tcttgatgcg ttacttgtta aaaaaccaat tttgggggca
     7861 gcagtggtta aagcgtgtcc atcgtagtat tctagagaac ctcaacaaac aggacattga
     7921 tttttcaaaa cttaagatgc caatccctac ggtagaaccg gggaaaattt ccgctcaaga
     7981 gttttggaaa acctatgtga gaacgaatac gccagtgatt atcaaaggtg gttcaaaaca
     8041 cacctttgcc tatcaaaact ggacaatgga aatgtttcgg gaacgctttg gtgactttaa
     8101 gaccgatctc atcagtcaaa gcagagatga gcatggtgct agtacattca aacctgttgt
     8161 tcatacgttt aaagatgtca ttaacagcag agaaagtgag gaaaaacttt atattgcgtt
     8221 ctgtgcagac atcttttcta cttatgcaga gttagtggat gaagtaggct gtttagagtt
     8281 tagaaagcac atgggtggca acactacttt cttcgctgga gcacaattgt ttttaggagc
     8341 aaaggcttta acgggtagtg atgtccattg tgcgaatgct aataacttgt ttttccaaat
     8401 tagcggccag aaaaagtgga cttttataca tccggattat ctgtggctaa tgtatccaat
     8461 gcttgatcgt ttctgtttgt attgtggttc ctttcttaaa agagaatacg accaagcata
     8521 tctcgagcaa tacgcaccac tgcaaagata ttgccccaat tacgaagctg tattggaacc
     8581 gggagatgtt ctccttaatc caccgtggca atggcatgct attgataacc tcactggtga
     8641 caatattgct gttgccactc gttggaccga tgctatagga cagaaacgtg caaatacatt
     8701 ttttgattgt atgcagtttt tctcaccata tatatggcgt cttcgatttg atttagtgac
     8761 caaaaatcct gatgccgtag gagtattgga tgaaagaaca aataatttag ttcagactca
     8821 agatgattat gttgggttgg ggaatgagaa tggagtgata gcctgggagt ttgatcgatg
     8881 gcccaagaag taccagtttt agaccctttc ctcattgcat attaagttta atagatatac
     8941 caatcgatca tttgtaagac gatgagacac aaactcatag ttgagtaata gccatgacta
     9001 caaccctcat caatgacagt aaatcccaga gtaatgggac aacgaagaaa ccgattccaa
     9061 gcttgtttcg cactttcaca gccattgtta tatcggttat ctatggtatc tacgaggtcg
     9121 tttttgtaca taaattcttt ttgtacacct ttttccgccc atttgtttct gatgttccgc
     9181 ctccagttca attaaatatt ggctattgga ataagcttca atttaaaatt attctaataa
     9241 tgcgttactt gttgaaagat caattttggg gacagcagtg gttgaagcgt gtacatcgta
     9301 gtattctgga taacctcgat aggcagagca tcgatttctc aaaacttaac atgccgatcc
     9361 ctacagtaga gccaggagaa atttcggctc aagagttttg gaacacttat gtgaaaacga
     9421 atacgccagt gattatcaaa ggtggttcaa aacacacctt tgcctatcaa aactggtcac
     9481 tagaaatgtt tcaagaacgt tttggtgact ttaaggttaa tattactaat cagagcaaaa
     9541 acgacgaacc tgatatttgt acattcaaag atgtcattga cagtgaggat aaactctata
     9601 tttcattctg tgcagatatc ttttctgctc atccagagtt agtggctgaa ttaggctgtt
     9661 tagacttcaa aaaatacatg ggtggcaacg ctacttactt cattggagca caggtgtttt
     9721 taggagcacg gtcctcaaca ggtactcatc ctcactgtgc taatggaaat aatctgttct
     9781 accaaattcg cggcaagaaa aagtggacgt ttgtgcatcc ggattatctg tggctaatgt
     9841 atccaatgct tgatcgctta tctttctttt gcgcttcttt tcttaaacga gattacgacc
     9901 aagcatatct cgatcaatac gcgccactgc agaaatattg tcccaaatat gaagctattt
     9961 tagaacctgg ggatattctc ctcaatccac catggcaatg gcatgctatt gacaatctga
    10021 ctggagaaaa tattgctgtt gctactcgtt gggctcctgc aacaggacaa aaacgtgcga
    10081 atacgttttt tgaatttatt cagttactct caccatatat gtggggtaca agatttgatg
    10141 tgttgaggaa acaacctgat gcagtaggtg tattagatga aaaagcaggt gatgcagtca
    10201 aaagccagga tgattttgtg aaattgggaa acgaggatgg attaataccc tgggagtttg
    10261 ataaatggcc caaggaatac cagttttaga gtttagcccc ttaactgaac catagaatca
    10321 agaaaacaaa gccttttgtg tccactaagt tttcgtaaag tatgtgattc aaattgtatg
    10381 aaatctatcc ccggtcccaa aactccaagc ttcctccaaa gtcttcagtg ggttttcgat
    10441 cccgttagct atctcaaaag cacacataat cgttatcctg acatctttat gaccaggaat
    10501 ctcgggcttg gatcaccaac ctctgttctc gttagtcatc cccaagcact acagcaactt
    10561 tttactagcg atcgcaagca gtttagtgtc cctgttgagt tcaaccgcat actgcaacct
    10621 ctgatagggg aattctcgat cttcctgata ggcggcaatc ttcatgcaaa acgtcgccag
    10681 ttagtcatgc cttccttcca cggtgatcgg attcgggcat acggggaact catttaccgc
    10741 atcacagagc aggtcatgga tcaacttcct cctggcaaat cgttcctagc gctggatgtc
    10801 atgcaagcta tttccttgga agtcatcatc aaagcagtct ttggtatatc aaaaggagaa
    10861 cgctatcttc ttcttaagca aaatatcctt tccttaacag agccagccag ttctcccctc
    10921 acctccgccc tcatcttctt tccaaatcta ctacagaatg attggggctc atggagtcct
    10981 tggggtaggt tcctaaagcg gcgacaacag acagatgacc taatatatgc tgaaattgcc
    11041 gagcgccgag ccaatcccga tccaaaccga actgatattc tcgccttact tatgaggtca
    11101 cgagatgaac agggacaggc tttaagcgat caagaattgc gagatgagtt aatgacccta
    11161 ttgttagcgg gctatgagac aacagctacc gcaattacat ggggattgta ttggatgcat
    11221 cgcttaccta atgtcaaaga aaagctttta aatgagttaa acagccttgg cgacttcaca
    11281 agtccactcg aaatcagtcg ccttccctat ctcagcgctt tctgtcaaga aactttgcgc
    11341 atctgcccag tagcaatgat caccttcccc agaattagct gtgaacctgt caagatttta
    11401 gggtacccca ttgaacctgg aactattatt gcaggttgta tatatctcac ccatcatagg
    11461 gaggatcttt atccaaactc aagcgaattt cgaccagaac gatttttgga gcgtcaatat
    11521 tcaccctacg aatttattgc ctttggcggt ggttcacgtc gttgtgtggg agatgcctta
    11581 gctcagtttg aaatgatgct catcttagcc actattgctt gccgctatca gcttgcatta
    11641 gccgatctac gcccagaaaa actccatcga cgaggactcg ctttagcccc ctccagaggg
    11701 gtcaagatgg ttatgcaaaa gaaaacaaag cgtgacgatt cagttgaacg cacattggcg
    11761 ctctttcatc actctgaata gagaaaattt atgtcctaat ttagaaaact aggtgtgttc
    11821 aagattttag ctgatttgta ataaataagt aaaaacatta gtcaattgat aagaggatgt
    11881 tttaaaaggg ccttttgaac ctcataatca agacagcgaa gcatcttagt atagaactaa
    11941 aaccttgatt tttcgttgca gttaagctga atcagaaact cctaattata ccttttcaaa
    12001 cttttaaaat atcctctaag agccattgta aatgaagggt tcatattttt atctgattaa
    12061 agtgatagaa gagcgagttc ttaatatgtc agccgactgt ccagtaagag taagacaatg
    12121 aaacacaaac tcataataca gttaagtatc agctatgact acaaccctaa tcaaagacaa
    12181 aaaatctcaa aataataaga tgaccaagaa atcagttcaa aacttgtttc gcactcttaa
    12241 agcccttgtt atattagcta tatacattac ttatgaggta gcctttgtac acaaattctt
    12301 tttgtatacc tttctccgct catcgatttc tgatgttccg cctccaattc ggttaaagat
    12361 tggctattgg aataagcttc aattcaaagc tattctcttg atgcgttact tgttaaaaga
    12421 ccaattttgg ggacagcagt ggttgaagcg tgtccatcgt agtattctag agaacctcaa
    12481 caaacaggac attgattttt caaaacttaa gctgccaatc ccaaccgtag aactagagca
    12541 aatttccgct caagagtttt ggaaaaccta tgtgagaacg aatacgccag tgattatcaa
    12601 aggtggtgca aaacacacct ttgcctacaa aaactggacg ctagaaatgt ttcgggaacg
    12661 ctttggtgac tttaaggtta atattaccaa tcaaagtaga aaccaacata aacccgatgt
    12721 tagtacgttc aaagatgtca ttgatagcag agaaagtgaa gaaaaactat atatttcatt
    12781 ctgtgcagat atcttctcta attacccaga gttgttgaat gagttaggct gtttagagtt
    12841 tacagcacac atgggtggca attctgtttg gtttgctgga gcacagttat ttttgggagc
    12901 aagttcctca acaggtactg atgctcattg tgctgatggt gataacctgt tttttcaaat
    12961 ccgtggcaag aagaaatgga cgtttgtgca tccagattat ctgtggttaa tgtatccaat
    13021 gcttgatcgt tggtttctat tttgcagttc gtttattaaa agagattacg accaagcata
    13081 tctagatcaa tatgcaccac tgcaaaaata ttgtcccaaa tacgaagccg tcttagaagc
    13141 gggcgatatt cttctaaacc caacatggca atggcatgct attgataata tcactgagga
    13201 aaatattgct attgctactc gttggtcttt catcaaacaa aaacgtgcaa atacattttt
    13261 tgatttcatt cagttgttct caccttatat atggcacatg cgatttggcg tcttaaaaaa
    13321 tcccgataaa gtagatttct tagaagatag aacaggtgat gtagtcaaga ataaagatga
    13381 ttttgtgaaa ttgggaagcg aaaacgaagt aatagcctgg gaatttgata gatggcccga
    13441 aaagtatcag ttttaaaact tttttccata gcaatcccat gtggcagata tgccaatcaa
    13501 tctattcagt aataagacac aaactcacac ttgagtaaca gccatgacta caaccctcat
    13561 acaagatgga aaatcccaaa gcaatggtgc aacaaagaaa tcgaatttaa gctggtttcg
    13621 cgccctcata gctatagttg tattggctat ctatggtatc tatgaggtag tctttgtaca
    13681 taaattcttt ttgcacacct ttttccgctc atcaatttct aatgttccac ctccgattgc
    13741 attgaagatt ggttattgga ataagcttca attcaaagct attctcttaa tacgttattt
    13801 cttgaaagac caattttggg gacaacagtg gttaaagcgt gtccaccgca gtattctaga
    13861 gaatctcaac aaacaggaca tcgatttttc aaaactcaag atgccgatcc caaccgtaga
    13921 actagagcaa atttccgctc aagagttttg gaaaacttat gtgagaacga atacgccagt
    13981 gattatcaaa ggtggtgcaa aacatacctt tgcctaccaa aattggacac tagaaatgtt
    14041 tcgggaacgc tttggtgatt ttaaggttaa tatcgtcaat cagagtaaaa acgaacataa
    14101 acctgatgtt agtacgttca aagatgtcat tgatagcaga ggaagtgaag aaaagcttta
    14161 tatcgcattc tgtgctgata tcttctctgc tcacccagag ttgttggacg aactaaactg
    14221 tttagatttc agaaaacata tgggcggcaa ctctgcttta tttggtggag cacagttgtt
    14281 tttaggagca agttcctcca caggtagcca tgctcattgt gctgacggta ataatctgtt
    14341 ttttcaaatt tatggtaaga aaaagtggac atttgtgcat ccagattatc tgtggttaat
    14401 gtatccaatg cttgatcgtt gttttctatt ttgcgcttcc tttgtgaaaa aggattacga
    14461 ccaagcatat ctagatcaat atgcgccact gcaaaaatat tgccccaaat acgaagccgt
    14521 cttggaaccg ggcgatattc tccttattcc agcatggcaa tggcatgcta ttgataatct
    14581 cactgaggaa actattgctg ttgccactcg ttggtctatg gtaaaacagg aacaagcaaa
    14641 tacatttttt aactttattc aattgttctc acccaaaatt tggcgtgttc gttttgctct
    14701 gttaacgaaa ggacccgatg aagccagttt agcattaggt gaaagaacag atgatgtagt
    14761 tcagagcaag aatgattttg ttagcttggg aaatgagcat agaataataa ctttggaatt
    14821 tgataaatgg cccaaggagt atcagtttta gatgcattgt ctagttaagg caaataacag
    14881 caggtagcag aatttaggcg ttgcaaaatt gaagtataaa ttttgtagaa agcctatata
    14941 ctgctctaga tgtagatcgc ctaagacttg taaaagctaa ttcttcgcca ggaaaagaaa
    15001 caccatgcag gtaacaacga acgaatttat taacagatat gacagtatga ttctaaaccc
    15061 tttgatgagg gagtactttg gtcaaaaagg ttttttcaat ttaggttatt ggctttcaaa
    15121 tacccaaagt gtacaggaaa gctgcgagaa ccttatggag aagcttttag aatttattcc
    15181 tcagaaaaag gggaaaattc ttgatgtcgc ctgcgggttg ggagcaacga ccagttattt
    15241 gttgaagtat tactcacctg ctgatatcgt aggcatcaat atttccacaa aacaattaga
    15301 gaaatgcaaa gtcaatgcac caggctgtaa cttcatcatc atggatgctg tgcagatgat
    15361 atttgaggat aattcgtttg ataatgtcat ttgtgttgaa gcagcctttc actttgatac
    15421 aagggagaga tttctacaag aagcttggcg tgtactaaag ccgggaggtt atttgatctt
    15481 gtctgacatt atctttaaaa aaagactgtt aacagatgat tggatgctgc tggaaaataa
    15541 gaatgttcaa aatattaagg aatataagga tctttattta aaagcaggat ttcaagatat
    15601 agaaattata gacacaacca atgaatcttg gatagaattt catcggcgtt tgaaaccctc
    15661 acttttgaag gagtatcagg acggaaattt agatgaatca acttaccgtt attacctcga
    15721 tattacagat gagaagctga attccggaaa tcagtatatt ttggtttcag caaagaagag
    15781 gaagacacta gagtgttgag ccacagttaa taccatttca caaaattatt gatacaaatc
    15841 ctctcccttg tcttccttgt ctcctgtcgc taaatgtatc aaacttatag tgaaacggta
    15901 taagccctct taccttcggc agataataat ctgaaaccct tctttttaga tagtttttca
    15961 acaagaggat ttaaatgaca aaggtggaat gcgatcacac aattcattga atggaaatgt
    16021 atttaaagtc tttatggaaa aatgcttact tctccaacta tgggagggtg ctgtagttgt
    16081 tatggataat gtcccggtgc ataaagtgga agaaatcgag cctttaattc aatcggttgg
    16141 cgcaagcgtt ctttatcagt caccctattc tcctgacttt aatccaatcg aacattggtg
    16201 gtcacaatta aaagcttttt tacgtcagtt ttctccaacc acttccaaaa tcgttgatat
    16261 tctaattgca attgtacttg atttaattaa tcctcaacat ttaaaaaact ggtttacaaa
    16321 ctgttgttac tgtacctcat aaacctgcaa tatgctctat gttcgcttcg ctcccaattg
    16381 cccgcaacag aatccaatgg aggatatttg gctgcaagcc aaaacatggg ttcgaagttc
    16441 ttgtgctttg attcctttct tctcacatta gtcgttactg tttcagtgtt ttatccaaca
    16501 caccactttt gattttctat ctctccagat atacggagtt ttttcaaaaa tcaaatagga
    16561 gtcctgtata ttatcttaag tgaagctcca tgatgctgca gacgctacac atccgcaagc
    16621 ttaaagcgaa cacctaattc atactttaca ttcagcaatt tttcaccttc caacaattta
    16681 cttaatttta aatgattatc aaatcaaatt gttcttatca ctcaaactat atgaataaat
    16741 ggtcaactct agtagatcta ctacgctacc gcgcacaaag tcagcctaac cgtagaattt
    16801 acacctttct acaggatgga gaaactgaat cagacagctt gactaattgg gaattggatc
    16861 aacaggcccg agcgctcgct gcccatctcc aatcccttga tcttgctggt gagcgtgcat
    16921 tattgattta cccaccaggt ctagaattta ttaccgcctt tttgggatgt ttatatgcat
    16981 ctgttattgc tgttcccgct tatccacatt tgcgacgcaa acagcatata tccaaattga
    17041 aggggatcgt agcagatact catgtaaagg tagcactaac ctcaacatcc ctattagcca
    17101 ctatagaagg gcaatttgcc caaaatgcag aattagcttc actacagtgc ttatcaactg
    17161 ataagatagc tagcaagctg gtatcagact ggcgaaaacc ggaaatcagc agtgaaactt
    17221 tagctttcct tcagtatacg tctggctcta caggctcgcc aaaaggggtg atggtcagtc
    17281 atggtaatat tttacacaat tcggagatca tctatacttg ttttggtcat acagatgata
    17341 gtcacgtagt ctcttggtta cccccttacc acgacatggg gttgattggt ggaatactac
    17401 agccgctcta cggtggtttt ccagtcacac tgatgtcgcc ggaaacattc attcaaaagc
    17461 ccttctgttg gttacagcaa atttctcgct ataaggcaac aacaagcggt ggaccgaatt
    17521 ttgcttatga tctatgcgtt cacaagatta aaccagaaca acttgcaagc ctcgatttga
    17581 gcagttggac gctagctttc acaggagctg agcctgtccg tgcagagaca atgaagcaat
    17641 ttgctgctgc ttttgaaccc tatggctttc aatgggaatc attttatccc tgctacggaa
    17701 tggcagaggg aactttaatt gtgtccggcg ggttaaaagc atctccacca gtcatttact
    17761 ttgttgaggg agcagcactt gaacaaaatc gtgtaatagc ttctgtagcc gagggtaaaa
    17821 gtgttcgggc aattgtaggt tgtggtcgaa gttggctaga ccagaaaatt gtgattgcta
    17881 accctgagtc cttaacccag tgcccagagg gacaagtagg agaaatttgg gtgctaggat
    17941 caagtgtcac tcagggttat tggaatcgac ataaggaaac tcaacagacc tttaaggctt
    18001 accttgcagg cacaggagaa ggaccatttc ttcggacagg tgacctagga tttttgcaag
    18061 atggtgagtt gttcgttaca ggccgcataa aagatgtaat tatcatccga ggaagaaatt
    18121 attaccctca agatattgaa ctgtcaatac agaaaattca tccatcatta cgtcctaatt
    18181 atggagctgc cttttctgtg gagatagagg atcaagaacg attgatggtg gctcaagaag
    18241 tggaacgcac ctgcatacga gaaataaatg ttgatgaagt tgttgaagca attcgtcggg
    18301 ctgtgtcaga acagcatggg ttacaggttt atggggtatt gttgctcaaa ccgggtagca
    18361 ttcctaaaac ttctagcgga aaaattcaac gttatgcttg tagagttagt ttcttagata
    18421 aaagtcttga cattgtcgga gattggatag gagatcctcg tcaaatagat ttactacaat
    18481 tgcagacaga aatagacgct ttgtgggagc aagtccaaaa ttcgacaaag caattgctat
    18541 ctaaaaagtt aaagtcagct aatcaaaagc agcgaataga catcctcatt acttatctaa
    18601 ctgagattgt ggtgagagtt ctacggttaa acgagaataa tttgcctaac ccaaagaaag
    18661 gtttctttga tatgggaatg gattctctaa tggcggtaga gttaggaaat cgcttgcaat
    18721 cagatttagg tatttcgttc tctgcaacaa cagtttttga gtattcaaat attgaggaac
    18781 ttgcatttca cttagataaa gttatccctc ttgatgttga gagacaaaaa tcgcaatcta
    18841 ctcaacaaaa agatagacca aatgagattt ctttgaaaca agtcagtcag ctttctgaaa
    18901 atgaacttca aagttcgatt gaagaagagc ttactcagct agaaactgct ttacaggaga
    18961 ttggcgatgg gcaacaaggt ttgtggaaat ggaagtcaac tattaacaca gcaacgtctt
    19021 ctgctagcac ttaagcaagc aaatgctaaa cttgatacaa tcaagaaagc ccaaactgag
    19081 ccgatcgcca ttattggaat aggttgtcgt tttcctggag gagcgaacag cccagagttt
    19141 tactggcggt tgcttcacga aggagtagat gctattactg atgttcctgc tacacgatgg
    19201 gacattaaca aatattatga tccgaagcct ggaactccgg ggaaaatgta cagccgttat
    19261 ggcggttttc ttcaacaacc catagaccaa ttcgatccac aattttttgg gatttctccc
    19321 cgagaggctg taaagttaga tcctcagcag cggcttctac ttgaagtggc ctgggaagca
    19381 attgaaaatg ccgggttggc agcagaaaat cttagaggta ctcaaacagg agtatttatt
    19441 ggcttaagta cccatgacta tgaatactca gtttttggag gtcatctaag tagcattgat
    19501 gcttacagtg ggttaggcaa tgcccgaagt attgctgctg gtcgaatttc ctacattctg
    19561 ggtctacaag gaccaacttt tcaactagat acagcctgct cctcatcttt agtagcagtt
    19621 catcttgcct gccagagctt gagagccaaa gagtgcaact tagctttagt cggtggggtt
    19681 aacctaatac tttccccagt tcccacaatt ttcttctgca aaacccaggc tttatcagcc
    19741 gatggtcgtt gtaaaacatt tgatgccaat gcagatggtt atgttcgagg agaaggatgt
    19801 ggaatattag ttctcaaatc tctaagtaag gctattgcag atagagataa tatcttagcc
    19861 ttaatccggg gaacagcaat taaccatgac ggagcaagta gtggattaac tgtgcctaat
    19921 aaacaggcac aaaaattact gcttcgtcaa gccttagata atgctacagt aaatccagca
    19981 gatgttagct acatcgaagc tcatggaaca ggaacccgtc ttggagaccc cgtagaggtt
    20041 gaggcattgg gagaggtgtt ttgggaaaat tgtccccgtc tgcaaccatt aactattggt
    20101 tcagctaaga cgaacattgg tcacttggaa gctgctgctg gagtagcggg tttagtcaaa
    20161 gttgtgctgg ctctacagca tcaggaaata cctcctcatc tacacttttc taaacccaat
    20221 ccttgtatac cttggaataa atttcctata ataattcctc agtcacagat gccttggctt
    20281 cgtggagaaa agccacggct agcaggggtt agttcctttg gttttagtgg caccaacgcc
    20341 catgttgttt tagaagaagc acctgtagta gaaccagttc caccaacagt agttcgtccg
    20401 attcatttac tgacactttc tgctaaaaca gaagcagcgc ttcaggagtt agcaactcgc
    20461 tatcagaatc atctagctac ttttgcagat ttggacttag gagatatctg ttttaacgcc
    20521 aatatagggc gctcccactt taaccaccgc ctagctatag ttgcttcctc gtccactgaa
    20581 cttaagcaaa aattggcaga cttcactact aaagaagaag tgacaggtat cttccgtggg
    20641 caactgccaa gcgtaattac cagacccaaa attgccttcc tattcactgg tcagggttcc
    20701 caatacctac atatgggaag gcaactgtat gaaactcagc ccaccttccg caaggcacta
    20761 gagcaatgcg acgctatttt acgtaactat ctggagaaac cactgctgca tatcttgtac
    20821 ccacaagcag gagaaacttc acccattgat gacacagctt acacccaacc cactctcttt
    20881 gcactggaat atgccttggc tgaactgtgg aaatcctggg gaattgaacc agatgtggtc
    20941 atgggtcaca gtgtgggaga atatgtggca gcttgtgtgg caggagtgtt tagcctggaa
    21001 gaagggctga agttaattgc taaccgagga cgtttcatgc aaaccttggt aaaaggcggt
    21061 gagatggtgg cagttttggc atctgagaat caagtacgag atctcatcaa gccttatgaa
    21121 tcacaagtct ctattgctgc agtcaatgga ctacaaagtg tggtaatttc tggcgctact
    21181 catgccattt gcactctgtg tgcaatgctt gagagtcaag gggtgaagac taagccattg
    21241 caagtatctc atgctttcca ctcacccttg atggaaccga tgatagctgc gtttgcagca
    21301 gtggtatcag aagtcactta ctctcagcct tgtataccta tagtttctaa tgtaactgga
    21361 gaacttgccg acgaggaaat tgccactgcc gaatattggg tagatcatgt acaacagcct
    21421 gtgagatttg ctgacggaat gcagactttg caccaacagg ggtgtgagct atttgtagaa
    21481 attggaccca aaccagtttt gttggggatg gggcgtcaat gtttgacaga agatgttgct
    21541 gtttggttgc cgagtctttg cccaagacaa ggagagtggc aacagatgct tcagagtcta
    21601 gcacagttat atgtgcgagg agtggcagtc aattggttag ggtttgatca aggttatgcc
    21661 cgtcgtaagg ttatgttgcc cacttatcct tttcaacgtc aatcctactg gtttgagacg
    21721 actgacactc ctcaccaaac acaacttttg tcaagaggta aaatttttca ccccttactt
    21781 ggtcaaaagt taaatttggc tggtttaaag caccagatcc gctttgaatc ccaaattagt
    21841 gcaaaggcac cagcatacct gtcacaccat caagtttttg gcaagcccct gctgccagca
    21901 gctgcttacc tagaaatggc cttagctgct ggctcaacct tgtttcagat cgaggggttg
    21961 atgcttgaag atgtcgttat tcagcaagga ttaatcctat ctgaggaaga agctaaaact
    22021 gtccaagtta ttctaacgat atccgaaact caagtttatg acttccaaat ttttagctta
    22081 aacttggaag aagctcaaaa agaacctcgc tggacactgc atactgaagg gaaattacga
    22141 attgaaaatc ttgaaaccct accctctaaa gccaatctag aaacttggca aattcagtgt
    22201 aatcaacaag tatcagtcac aaactactac cagcaatatc atgatctcgg cattgattac
    22261 ggttcttctt tcaaggttat tcaacaattg tggcggactg aaggaaaagc tcttggtcaa
    22321 attcagctac cacaagcatt tgttttagaa gcagattacc aaattcaccc tattctgcta
    22381 gatgctagtt ttcaagtctt agtagctgca attagtacaa ctcatttcca agatatttat
    22441 ttaccagtgg gagtagaacg actgcgagtg tatcgtcgtc caagtacttt tttatgggcg
    22501 caagtggaga taatcaagga acctaattca caaactttag ctgctgaagt ttgtctattg
    22561 gacgctgatg gacagttagt tgcaatagtc gaaggcttac aggccaaaca agcaactcct
    22621 caagccttgg tgggtaatca acaagagcct ctacaaaatt ggctttacga agtggagtgg
    22681 cgacctcagg tgcgtttcag ttggcaactg tcgtctaagt atctgcccac acctgcagaa
    22741 attcaccccc aacttcattc tcaagtttct agtttaataa atcaaccaga tttagtaatc
    22801 tatcaagatt ttctcactca attagaaagc ttaagcattg actatgtact ccaagctttc
    22861 catcaattag gttggcaatt ccagctagga cagcttttct caacaaactt aatcgctgaa
    22921 cagttagggg tagttaaaca acaccaccga ctttttagtc gtttgcttga gatgctaaac
    22981 gaagttggca ttctacgctc tttcgaggac aaatgggaag ttcttcaagt ccctctaaca
    23041 gcaaacccac aagagcaagc gcatactttg gtacagcaat atcctagcgc cttagcggag
    23101 ctcaccttac taaaacgttg tggggcacag ctggcttcag tgcttcaagg aaactgcgat
    23161 ccccttcaac ttatttttcc tgaaggcgat ttagcaaccg tcacccaatt gtatcaggat
    23221 tccccagggg ctaagattat gaatcacctg atgcaacaag ctattagttt agccttagaa
    23281 cagataccca aagcccaggg ggtacgagta ttagaaattg gagcgggaac tggaggaaca
    23341 actgcccata tcctacctca cctgaatcca gctcaaacaa agtatgtctt tacagacgtc
    23401 agcactctat tcactattaa cgcccaagag aagtttcggg attacccttt tgtctcttat
    23461 caaaccctag acatcgaaca aaatccaatt gaacaaggat ttgaacctca tcagtacgat
    23521 attatcgtga tagctaacgc cttacatgcc acagctgatt tgcgtcagtc cttgcagaac
    23581 atacggcaat tattatctcc aaagggtcta ttagtactgt tagaaggaac tagtcggcag
    23641 cgttggttgg atcttatctt cggtttgtta gaaggatggt ggcggtttac tgatgtggat
    23701 ttacgttcaa attatccact gctgacaaca tcccagtggc agacactttt acaagaaagt
    23761 ggtttgcaac tgacagctaa tctcctatca acccaagaag attccaaagt tttatcccaa
    23821 caggtagtga ttgtcgctca agcagtcgat gtcctcccac cctcaacctt acatgaaccg
    23881 aaaggttggc ttattttggt agatgagcaa gggctgggtt cgcaattggc agcccaactg
    23941 cgtgcaaaag gagaggcttg taccctcgtt ttgcctggtg aaggatatca acaagttggg
    24001 gagcaacagt ttattatcaa tccaaactcc tctgaagact tccagcaaat cgtatcaaaa
    24061 gtggcatcat gtcagcctgc tttatatggg gttatccaat gctggagttt agagacagta
    24121 gagtctaaag ctttatctag cgaggagtta aaagcacttt gccagagaga gtgtggtagt
    24181 actttatatt taatacaagc cttagttaag gtagggatgg ttcagccgcc tcggttatgg
    24241 ttagtcactc gaggatgtca gccgattccc gaccttcatc cagctatctc aagtgtggcg
    24301 cattccccac tatggggaat ggggaaagtt attgccttag agcatccaga actcaagtgt
    24361 gtacggattg atttagaccc tggcacagta agagatgagg cacaaacttt gtttgaagaa
    24421 atttggtcgg aagatactga agaccaagtt gcttttcgtg aaggaatccg ttatgtggct
    24481 aggttaattc ggagtcgtca gacccgagaa tctttaagaa aagagcaact gaagatttct
    24541 catgcccagc catttcgatt gaccatctcc acgaaaggta ctttagagaa cttaacttta
    24601 gaaccaacaa ctcgccgccc tccaagtgct ggtgaagtag aaattcaagt caaagccaca
    24661 ggactaaact ttctagatgt tgttaatgcc ttgggattag tacctaaaga ggttgctgga
    24721 gtatcccaag aacacctgct caaaatagat ggttttggtg gtgaatttgc tggtgaagtg
    24781 gtttcaattg gcgaagaagt tcaaggtttt gaaatcggtg attcggtcat tggtttggcc
    24841 cctgaaagtt ttagcaaata cgttacagtc agtgccactt tggtagtatc taaaccagag
    24901 aacctcaact ttgaggaagc cgcagcaatt cctattaatt ttctgactgc ttactatgca
    24961 ctctatcatg ttgctcaaat ctcagcggga gatcgagtat tgattcatgc agcagcggga
    25021 ggaactggaa tggctgctgt ccaaattgct caacaagtag gtgcagaagt ttttgcgact
    25081 gctagttcct caaaatggga agttctcaga tctatgggag tacaatacat tatgaactcc
    25141 cgtactctgg attttgctga ggaggtgatg aaaatcaccc gaggggacgg tgtagacatt
    25201 gtcctcaact cccttacctc caaagaattc attgccaaga gtctttcagt cgtcaagtct
    25261 caaggttgct tcttggaact cgcaaaacga gatgtttgga actctaacct tatggctgag
    25321 gcaagaggcg atgtttctta ttgcattatt gatcttctta ggatgtctca acaacaaccg
    25381 gatttaattc gatccatgtt gttagacttg atgcatatgt ttcatgaagg taaactacaa
    25441 ctgccaccaa tgaaagtgtt tcccattcag gatgttgtca gtgccttccg ctatatgcaa
    25501 caagcgaaac atattggtaa ggttattgtt actcactctt tagaacagtc tgactctaca
    25561 tctgaacgtc ctctaacttt ccgaggagac agtacctact taatcactgg aggtttagga
    25621 ggtctaggtt tacttgtggc tcgatggatg gtagataatg gtgctcgtca tctagtctta
    25681 gtcggtcgca gtggaaccaa ggataacatc aggagtcaac tagaggaatt gcaacacaaa
    25741 ggtgctaacg tcattgtgac ccaagcagat gtatctgaga ctgaggcgat cgctcgagta
    25801 ttaacagaca tcaagcaatc cctaccagca ctgcgaggta ttattcattc tgtaggagtg
    25861 ttagacgatg gggtgttgca gcagcaaact tgggagcgct ttgcccaagt acttgctccc
    25921 aaagtccaag gagcttggaa tctccacaac ttaactcaac atcagccttt ggactttttc
    25981 atactatttt cttctgtagc ttctctactg ggttctcccg gtcaagccag ccattcagcc
    26041 gctaatgctt ttctggatgc tttagcctat caccgtcggg ctcaaggatt aatgggacta
    26101 agcattaact ggggagcgat cgccgagata ggagcagcag ccaagcgaca gataagtcag
    26161 cgtcctaaca aaaatgggat caaagctatt cctccccaaa aagttttaga agcgttagag
    26221 caactgatga gtagttcctc tgtagaagtt ggagttgtac caatttgctg gtcagaattt
    26281 ataaaccaac cctcactttc tcccttcttc agtgattgga aaaagatatc tgaactacca
    26341 tcgttaactc aaacagattt tctccaaaaa ttattagcag cacctactaa caactttcga
    26401 gaacttttaa gtgaacatat ttgtttgcaa gtagcaaaag tattaggcat aaactcatcc
    26461 caatcaatcg acctacaaca aggttttttt gagttaggaa tggactcact gacatctgta
    26521 gagttgagaa atcgcttgca aaccagccta aaatgttcaa ttccctcaac actagctttt
    26581 gactatccta gcgttgaaaa attggtagac tacttgtctc atgaaatttt aggaacagaa
    26641 tctcttaaga attctgctgt tgggttaaat aaaggtgaag agaaaaatga taagaaggta
    26701 gaaaaaacat cagtcaatat cgaatcacta tcggaaaacg aattagaaga gctaattaac
    26761 caaaaattga aatctttgat taaggaggag caaagtgggt atgattattg aacagatgag
    26821 ccagttatct cctctgcagc gttcattttt agtcattgag cggttgcaat caaaattaga
    26881 tgcactgaaa gattctgcaa aagagcctgt tgctattatt ggtatgggct gccgatttcc
    26941 tggaggcgct aagaccccag aagctctttg gcatctatta catgatggaa aaagtgccat
    27001 caccgaagtt cctgcaagcc gatgggatat agaggcttac tatgacccta acccagcgac
    27061 tttggggaaa atgtacacgc gctatggcgg tttcattgaa cagttccaag aatttgaccc
    27121 ccagttcttt ggtatctctc cccgagaagt gctcagcctt gatccgcaac aacgtttgtt
    27181 actagaagtc agttgggaag cgctggaaaa tgcaggttta aatcctcagc agcttgctgg
    27241 aactccaacg ggtgtattca tcggcatctg tagcaatgac tactccaagc gcttgttagc
    27301 tagaggtttg tctaaaattg atgctcatct aggtactggt actgcccata gtgtagcatc
    27361 cggtcgctta tcttacagct taggtttgac tggtccaagt gtagcagtag atactgcctg
    27421 ctcttcagca ttagtaacga ttcatttagc ttgccaaagc ttgcgtaata gagagagcaa
    27481 tttagcttta gcaggaggtg ttaacttgct cctctcgcca gaaataaccc ttaccttctg
    27541 caaagctcgt atgttatctc gggatgggta ttgcaagact tttgatgcaa gtgctgacgg
    27601 ctatgttcgt gctgagggat gcggcatcat tattctcaaa cgtttatccg atgcggtggc
    27661 taatggagac aatattttag cagtcatccg tggctctgct gttaatcaag atggtcgaag
    27721 tagtggctta actgtaccca atgggccatc tcagcaagca gttattcgcc aagctctaga
    27781 aaatggcgga gtcgatcctg ctcaagtcag ttatattgaa gctcatggga caggcacatc
    27841 tctgggtgac ccaattgaag tcagggcgtt gggagaggta tttagttcta gtcactccca
    27901 aaaacatcct ttgatcatcg gttcagttaa gaccaatata ggtcacctgg aagctgcagc
    27961 aggtattgca ggtcttataa aagtaatcct acaactgcaa cacaaagaaa ttgctcccca
    28021 tctgcacttg aaacaaccta acccccatat taactgggat gaactaccaa tagtagtgcc
    28081 acttcacctc actccttggc ttcgtggaga aaagccacgg ctagcagggg ttagttcctt
    28141 tggttttagt ggcaccaacg cccatgttgt tttagaagaa gcacctgtag tagaaccagt
    28201 tccaccaaca gtagttcgtc cgattcattt actgacgctt tctgctaaaa cagaagcagc
    28261 gcttcaggag ttagcaactc gctatcagaa tcatctagct acttttgcag atttggactt
    28321 aggagatatc tgttttaacg ccaatatagg gcgctcccac tttaaccacc gcctagctat
    28381 agttgcttcc tcgtccactg aacttaagca aaaattggca gacttcacta ctaaagaaga
    28441 agtgacaggt atcttccgtg ggcaactgcc aagcgtaatt accagaccca aaatagcctt
    28501 tctattcact ggtcagggtt cccaatacct acatatggga aggcaactgt atgaaactca
    28561 gcccaccttc cgcaaggcac tagagcaatg cgacgctatt ttacgtaact atctggagaa
    28621 accactgctg catatcttgt acccacaagc aggagaaact tcacccattg atgacacagc
    28681 ttacacccaa cccaccctct ttgcactgga atatgccttg gctgaactgt ggaaatcctg
    28741 gggaattgaa ccagatatgg tcatgggtca cagtgtggga gaatatgtgg cagcttgtgt
    28801 ggcaggagtg tttagcctgg aagaagggct gaagttaatt gctaaccgag gacgtttcat
    28861 gcaaaccttg gtaaaaggcg gtgagatggt ggcagttttg gcatctgaga atcaagtacg
    28921 agatctcatc aagccttatg aatcacaagt ctctattgct gcagtcaatg gactacaaag
    28981 tgtggtaatt tctggcgcta ctcatgccat ttgcactctg tgtgcaatgc ttgagagtca
    29041 aggggtgaag actaagccat tgcaagtatc tcatgctttc cactcaccct tgatggaacc
    29101 gatgatagct gcgtttgcag cagtggtatc agaagtcact tactctcagc cttgtatacc
    29161 tatagtttct aatgtaactg gagaacttgc cgacgaggaa attgccactg ccgaatattg
    29221 ggtagatcat gtacaacagc ctgtgagatt tgctgacgga atgcagactt tgcaccaaca
    29281 ggggtgtgag ctatttgtag aaattggacc caaaccagtt ttgttgggga tggggcgtca
    29341 atgtttgaca gaagatgttg ctgtttggtt gccgagtctt tgcccaagac aaggagagtg
    29401 gcaacagatg cttcagagtc tagcacagtt atatgtgcga ggagtggcag tcaattggtt
    29461 agggtttgat caaggttatg cccgtcgtaa ggttatgttg cccacttatc cttttcaacg
    29521 tcaatcctac tggtttgaga cgactgatga aaatggatac caaaaaacag ggattgcacc
    29581 ttcagagaaa cataaatctc caatcactaa ctttcttgat caaggaaata ccgaacagtt
    29641 aactcaatat ttagaaaaga cagcaaacct ttcagaagct cagcgagcat cactgtctga
    29701 actactggaa ctcttagtca gagaacatca aaaacacctc ttggttaaaa gcaatattgt
    29761 atttgactat tataactccc tctcaaggac tagttctgaa tcaagtcaag agaaatattt
    29821 aacttttgct ccttttccta aaattgtgcc agggttttca tggcttctga ctcttgctga
    29881 gccacagaag tatcaaaaat atatgcaggc taccttagat gcacaaaagg aaatgagaga
    29941 tgtcctattt gcaaaagtgg atttctcatc ttctacaaag gtattagatt ttggctgtgg
    30001 atatggctcg gatttaatag atctagccga aaaatattcc catctcaaac tatatggata
    30061 caccatatct agtgagcaag caaaaattgc tacgaaaaaa attcatgagc gtcatctaca
    30121 agaacgtgtc acagttttta atcgtgatag ttcaaaagat gaatttacag agcaatatga
    30181 tctggaattt ggatttgaag tagcgcatca tataaaagac aaaagtgctt tattctcaaa
    30241 tttgggtaga tctttaaaag atgaaggttt cttagtttta gctgatttta tttctaacgc
    30301 aacttttcca attgagcatc atgagacatc ttcctacttc attactaaag aagaatgggt
    30361 tgagcagctt tcacacaatc atctaaaaat tatcgattgc atagatgtta gtcaagaaat
    30421 agccaatttt ctctatgatc caaattttga agaaaatcta gagaagcttt atcaaactaa
    30481 tccagacgat aacataagag cagctttgca atcttataat cagttaggta agttacttgg
    30541 taatggtcta gcaagctatg tactgttgac tgctcagaag gaaaaccatc tgtcaaaaga
    30601 caaaattcac gacttgaaca aacagagatt aaatacactt gtttcttact cacagagagc
    30661 atttaagcaa tggctttatg aaattgagtg gcagcctaaa gcttttcatg caatagacca
    30721 aaacttgagt caaagtcaga aaaatcagcc aggaagttgg ttaatttttg ctgaccaagg
    30781 tggtgtggga gaagccttgg ctcagcattt agagaagcaa ggtgagcact gtattctctt
    30841 ttttccagga aaagagtgtg aaattttaga ggcagaacat tggacaattg actacaccaa
    30901 tccagaaaag tttcagcagc agatcaagga gattttgaag aaaaataaac ggctatgtcg
    30961 tggagtagtt catttgtgga gtttagactc gtcactttct gaaaatttaa ccacatcatt
    31021 attgaaagcc acgcaaacta aaaattgcgg tagtgtatta aacttggttc aagctttagc
    31081 tcaattagaa gtttctgaac tccctcgtct ttggttagtg actaaaggtg ctcaagtagt
    31141 aggacaaact caaacaactt tgcaggtgca acaagctcct ctgtggggat taagccgggt
    31201 gattgctaaa gagcatccta atcttcgctg tgtatgcttg gacttggaac aaacagagca
    31261 atcaaataaa attcaagata tttatcaaga attgtggttc tcagatcaag aagaccaaat
    31321 cgcttatcgt caaggagtac gttatgtagc tagactagta caacggtctt ctcaagtatc
    31381 tgtgagtcag atatcagtta atgagaacag cagctatttg gtcactggtg gacttggggc
    31441 gctggggctt aaggttgccc actggatggt aaaacaggga gcaaagcatc tgattttaat
    31501 cagtcgtcgt gaggtttcgg atgtagacca aacgtcagtc agtcagttag agcaagctgg
    31561 agcccaggtt ttggtcgtta agtctgatgt ttctgatcag atggatttag ctagaacgct
    31621 acaagagatt aagtcatcca tgccaccctt acgaggtata gttcacgcag ctggtattct
    31681 ggatgacggg gttttattac agcaaaactg ggaacgcttt gccagtgtga tggctccgaa
    31741 ggttgaagga gcttggaatt tgcactcctt aacccaaaac ttaccgttgg acttttttgt
    31801 ttgtttttcc tctgttgccg cagttttagg ttcaccaggg caaggaaatt atgcagcggc
    31861 taatgctttc ctagacgccc tagcctacta tcgtcggtca ttaggtttgt cggccttaag
    31921 catcaactgg ggaccttgga caaatactgg aatggtagca ggtttggaaa gtcgtcacca
    31981 agctcggttg gccgttcaag gaatgggtac aatagcccca gagcaaggat tgcaagtact
    32041 aggagaattg ttgggacaga atacacctca ggtaatggca ctaccagtta attggacgaa
    32101 gtttctgagc cactttccag cggatatgta tcctgcctta ctcttggaaa tagctcacca
    32161 agaacagcaa caatggaaac ttgagcgatc accagcacaa caacttgaac ttctcggtca
    32221 actgaaagca gccaacccca gtgatcgcct agaacttttg gtaacttatt tgcaaactcg
    32281 agtagctaaa atcctcggac taggcgcatc ccttcagcca gagcctgatg actcattaaa
    32341 cgagttaggg cttgactctt taatgggcat tgagctgaag aaccgaatca ccactgaatt
    32401 gggagtaaat atacctttac aaaagtttac tgaagggatc agcatcaagc agttggcttt
    32461 agctgtactt gaagagttaa tgttgacaag cataatccag tcaaatttct tttctcaaga
    32521 gcttaatgac gatgtagagg aaatcacaat atgaacctga atgaactttt gactgagctt
    32581 tcccagcaaa atatggaatt gcgggctgag ggtgatcaag tacgtgttcg tgctgcaaaa
    32641 ggaacactaa caccagaaat acgcgattct atagctgagc acaagacaca gcttctcgat
    32701 ttgctgcaaa aaagcaatat gagagcagat aatacttccc taccatcagt ggtgcctgca
    32761 cctgataaac gctacgatcc ctttcctctg actgacatcc agtatgccta ctggatagga
    32821 cgcaatgaaa tatatgaact aggcaatgtt gttactcacg cttatttgga attggattgt
    32881 caggacttaa atctagagcg actcaattta gcctggcaaa aagttatcga gcgtcatgag
    32941 atgttgcggg ctgtggtgtt accagatggt cagcagcaga ttcttgagca agtgcctcct
    33001 tatcaaatct cggtcttgga cttatgtgga caaagtgctg aaagtataga ctttactttt
    33061 gagacacttc gtcagcgaat gtctcatcag gttcgactag ctgatcaatg gccattgttt
    33121 gaaattcaag ctgttcacct ggataatcag cacttccaac ttcacctcag cttcgatgta
    33181 ttaatgatcg acatgggaag cctactttgt cttttcaggg agtggagtca gctttaccag
    33241 aacccaaaat tggagttacc actactggaa ctttcattcc gagattacgt tttagctgaa
    33301 aagcgcttag tagaaaccca attatatcag cgatcccaag actattggtt caaccgttta
    33361 gatactttac ctccagcccc agaacttccg ctactcaaaa gtccaagctc ttgccatcaa
    33421 ccccgatttc atcgtcgcac ttttcgactt gatccagaac tttggcaaca gcttaaaaaa
    33481 cgtgcaataa gtactaactt aacttcctcc ggagttctgc ttgcggcttt tgctgaagtt
    33541 ttgacagctt ggagcaaata tcctcaattt actattaata tcactctgtt taaccgttta
    33601 ccgcttcacc ctcaagtcaa tcaaattgct ggggatttta cttctttaac attgctgcaa
    33661 gttgacaact caacagttaa tgaatcattt gcctctcgtg ctgtccgtct ccaaaagcaa
    33721 ctttggcaag atttagacta tcaccatgtt agcggagtac atatcctaag agaattagcg
    33781 cgtagacaag gtaactctcg aaggtcaatt atgcctattg tcttcacaag tgccttggct
    33841 gttgattcct tggatcgcaa caattctgga ttgagtcaat ttggagaaat ggtttatggt
    33901 gtgagccaaa cacctcaagt tttgttagat catcaagtca ttgaacaaga ccaaggatta
    33961 attttcaact gggacgctgt ggaaaacctc tttcctccag ggatgttgga agatatgttc
    34021 aacacctact gccatttttt agcgcgacta gctacagatg aatcagtatg gtactcaaca
    34081 accagacaac ttatcccccc agagcaatta tcccaaagag acactatcaa tgctacagag
    34141 gcacctttgt ctaatgaaat gttgcacact ctatttataa gtcaggtaga gcgttgtagc
    34201 gatcattgtg ccgtaatctc gccccagcgc accttgactt atttagagtt aagtaaatta
    34261 gctcgtcaag ttgggtataa gttgcgacaa ctaggagcct ctcccaataa tttagtagct
    34321 gtagtgatgg agaaaggctg ggagcaagtc gttggcgtac tggggatatt aatgtcgggt
    34381 gcagcttatc tcccaattga tccagagtta ccaactgagc gccaaaagta tctgctcgat
    34441 caaggcgaag ttaaaatagc tttaactcaa tcacatctca atgaaaaact agagtggtct
    34501 gcaggtattt atagactaaa cgttgacaat caaaagttga cagatgagaa cctgcctatc
    34561 tttgaatcag ttcagagtcc agaagatctg gcttacgtcg tctatacttc tggctcaaca
    34621 ggtgtaccta agggagtgat gattgaccat caaggtgctg tgaataccat ccttgatatt
    34681 aatcaacgct ttcaggttgg agagcaagat cgtgtactag ccctttcagc tttgaacttt
    34741 gatttatcag tctacgatat cttcggtatt ttagctgctg gaggaactat tgtgattcct
    34801 gaagcagcag caactaaaga cccatctcac tggatggaac tcatagctcg tcaccaggtg
    34861 acattatgga actcagttcc agccttgatg cagatgtttg ttgaatatgt acggctccat
    34921 cctaacaagg tgtctcagtc tttacgtttg gctcttctaa gtggagattg gttgccactg
    34981 aacttaccta ctcaaatcaa aagtttatgg ccaaatgctc tggttgtcag cttaggggga
    35041 gcaactgaag cttcaatatg gtctatcttt tatcccattg aaaaggtttc ttcagaatgg
    35101 aaaagtattc cttatggtcg gccaatgacc aaccagtact tttatgtgct gaatgaagcg
    35161 ctagaaccat gtccagtatg ggttacagga cagctttaca ttgggggaac aggattagct
    35221 aaaggttatt ggaaagatga tcttaaaact cacagcagct tcattattca tccccgtaca
    35281 agaaagcgat tatacaaaac aggtgacttg ggtcgttatc tacctgatgg caatattgag
    35341 tttctgggac gaaaggattt ccaggtcaaa atcaacggct accgcattga actaggtgaa
    35401 attgagacta tacttgagca acatccatta gtcaatcatg ctgtggtgac agcagcagga
    35461 gagacacgag aaaacaaaca attggtagcc tatatcgttt cgaactcctt ctcaagctct
    35521 caagaacagc tagctgcctc taatcagata gcagaagctt acagaccatc acaatccaac
    35581 aaagtactga cagatcctgt aaaacgcttg gaatttaagc ttaagcagcc cggattacgc
    35641 ttgctcgaaa ctaatagatt ttctgtcgag ctgatcaaac cgcagttcga cgaagtattg
    35701 atccaaacct atgtgaaacg tcaaagctat cgtcattttt tggatacccc cattccgttt
    35761 gctcagttca gtgagctttt gagttgtctg ctacaaatca agctaaataa cgctccattg
    35821 cctaagtacc gctatgcatc ggctggcaac ctttatccag tacagactta cctatatgtc
    35881 aaacctgggc gagttgaagg gttggaagca ggtacttact attaccatcc cgcagatcac
    35941 cgtttagtat tactctctcc tgaggctgtg attgaacgcc acattcacag tgagattaat
    36001 caacctattt tcgatgaatc agccttttcg ctatttttaa ttggacaact aagtgccatt
    36061 acccccatgt atggggagtt agctagagac ttttgcttgt tggaagcggg ttatataagc
    36121 cagttgctca tgagtgtagc accagctagc caaattgggc tttgtcctgt gggtgctcag
    36181 gatttcgcag cgatacaaaa tgtcttcgag atcgattcca atcatattct gctgcacagt
    36241 tttttcggtg gaagaatcga gctagaaaaa actcagcaag cgttgcagcc caaagcaact
    36301 ccgtcagtag ctactattgc tgatgaactg cggagctttt tgcaagggaa agtgccagat
    36361 tatatggtac ctgcgattta tgtgcttctt gataccttgc cgctaacagt aaatggaaaa
    36421 gtggatcgtc gggcattacc tacaccagct ttggtacagt caaagcttaa tgtggtcgat
    36481 gcaccacccc aaaccgaagt ggagcgaacc ttagcaaaca ttgtgcaagc agtgcttcaa
    36541 gtcgaaacag ttggtatcca tagcaatttc tttgaactgg gagcaaattc tgttcacatg
    36601 attcaaattt acaacaagct caaagaagct ttaggtatag acgtagcgat tgttgaaatg
    36661 ttcaagcatc caactattaa ctttttagct aaatacttaa gtcaggaaat tgatgaatca
    36721 tcatctttag agcaaattca tgaccgggtt ttcaagcaaa aagaagctat aaaacaacaa
    36781 aagcgactga tggagaagag aaaaaatgga tagtgaggtt aattctgact caattgaaag
    36841 cattgctatt attggcatga gtggtcgatt tcctggagcc aaaaatttga atgagttttg
    36901 gcagaacctg cgagacggaa aagagtctat ttcctttttc tctgagcagg aactcattga
    36961 taatggaatc gacccagtta tggtgagtca ctctaattat gtgaaggcag gtgcgattct
    37021 agaagatgta gatctgtttg atgcttcctt cttcagcttc agcaataggg aggctacttt
    37081 catggaccct caacaccgct tcttcatgga atgtgcttgg gaagccttag aaagcgcagg
    37141 ctacacctca gaaacctacg acggtaagat tggtgtttat gctggttcaa gtatgaacag
    37201 ttatctgctg tccaatttac atcaacactt tgatcctaca attggaaccg acattctcca
    37261 agccctgatt ggcaatgata aagattacct gacaacccgc ctttcttaca aattaaactt
    37321 gaaaggacca agtattacgg ttcaaaccgc ttgttctaca tcattagttg ctgtctgtca
    37381 aggttgccaa agcttactaa actaccaatg tgatatggct ttggcaggtg gcgtttccat
    37441 caggttgccc ctcaaagcag gctatttgtt tgaaaaaggc agtatacttt ctcctgacgg
    37501 acattgccga gcatttgatg ctcgcgccca aggaactatt tttggtagcg gtgttggtgt
    37561 agtcgtgcta aaacggctgg cagatgcgat caatgatcgc gacgacattc atgccgtaat
    37621 caaaggctgc gcgatcaata atgatggagc tttgaaagtt gggtacactg cacctgggtt
    37681 agatggtcag gcagaggtga ttggaatggc ccaggtcttg gcaggggttg agcctgaaac
    37741 cattacttat atagaagccc acggtacggg aacttcaatc ggtgacccaa ttgaggttgc
    37801 agcgctcacg caggttttta gagccagtac taagaaaaaa gggttctgtg caattggttc
    37861 agtcaaaacc aatattggtc atttggaggc tgctgcggga gtagcaagct taatcaagac
    37921 tgtcttagca ctcaaacaca agcttattcc ccccagcata aactttgtgg tgcccaatcc
    37981 tcaaattgat ttcgcaaaaa gtcctttcta cgtcaacacc aagctggcgg aatggcagac
    38041 aaatggattt cccaggcgag ctggagtgag ctcctttggg attggaggca ccaatgctca
    38101 tgtcgttctg gaagaagcac ccagaccaaa actgaaacac atacagcaag agcgtccgat
    38161 ccatctcctt tgcctgtcag caaagagcga aaaggcgttg agagaacttg cccagcagtt
    38221 cggaagtcat ttagcagcaa atccatccgc acagttggga gacatttgtt tcacagcaaa
    38281 tgcagggcga tcacattttt ctcaccgtct agttgtagta ggtgagtcaa aagaacaaat
    38341 gcacgataag ctaaatgctt tcactgcgtc tcgggagaca tctgaagtgc tgagtatgta
    38401 cgtgctgagt tcaaatcagc agaagatagc tttcttattc accggtcagg gctcccagta
    38461 tgtaggcatg ggacgtcagc tctatgacac acaaccaatt ttccgcgaga tccttaacag
    38521 gtgtgacaaa atactgtatc cctatctaaa gcagtccttg ttgtcagtgc tttatccaga
    38581 accgagtact atctcgccct tagatgagac agcattcacc caacccgcac tatttgcctt
    38641 ggaatacgcc ctaaccgagt tattgcagtc gtggggcata aaaccatctg tggtgatggg
    38701 gcacagttta ggggaatacg tggctgcctg tgtggctggg gtgttcagcc tagaagatgg
    38761 gctcaagctt gttgccgaac gcagtcggct gatgcaatct ttaccacagg atggtgcgat
    38821 ggcagtggtg tttacctcta aagcgcgggt agtagctgct attcaaacct atgcgagaga
    38881 agtggtaatc gcatctgtga atggtccgca gaatattgtg atttctggca agcgtgaggc
    38941 agtaaacgaa gtaatagccg tcctgcaagc tgaagaagtc cagactagaa ttttgaaggt
    39001 ttcccatgcc ttccattctc ccctgatgga gccaatgctg gcgacttttg agcagattgc
    39061 taagcaaatc acttactcat ctccgcgctt agacgtaatt tctaatgtca ctggagagat
    39121 agccaaaagg gagatagcca ccccacaata ttggtgccgt catatacgac aaccagttaa
    39181 atttgctgca agtatggaaa ccctttatca gcaaggttat gaaatattcc tagaaatagg
    39241 tccaaagcca actctattag gaatgggtcg tcaatgtctg ccagaaggat caagagcttg
    39301 gctacctagt ctgcgtcaag ggcattcgga ttggcaacag ctactccaga gtttaggaga
    39361 gctgtatgtg cggggggcaa aagtagattg gtttggcttt gatcagggtt atccacgtta
    39421 ccgtgttcaa ttgccaactt atccttggca gcgatcgtgt cattggttgg aagaggctca
    39481 tgaggaacgg ctagataaga agttagaagc ctcgcacctt tgggagaccg cagtgtcagc
    39541 tagtcgctat caagcccacc gaggtccatt ggatttagcg ctccacacct actcagctaa
    39601 acaagagttt ttggagcgct tgacaactgc atatataaca gaagtgctgt tcaacttggg
    39661 tgcttatatc caagctggtg aaagacattc tgtggatgat ttattgcatc agtttaagat
    39721 ttcatcgacc tacagaaaac ttctttctct atggctagag aaaatgacca acgctggtct
    39781 cctaaagcaa caagaagagg aaatctttgt ctgcgatcac cccttggctt gttcccaaat
    39841 ggattctctc ttcagtgagg tcagagaaat tttcacagac gctccttttt tgttggatta
    39901 tttacagtac tgcggcagtc ggttagcaga catcttggca agcaagcaga cttcgttaga
    39961 aaccctattt cttggaggtt ctttagacac atctgaaaac ttttatggaa aatgggctgt
    40021 ggctcgctac ttcaatgata tcattagaag tattaccgaa tcggtagtga aagccctgtc
    40081 gccaggaaag cagttacgga ttttagaaat cggggccgga acaggggcaa caactgcatc
    40141 tgttctatca gtattgccac ctgaaaaaac catttattat ttcactgatg tttcagactt
    40201 tctctttacc cgagccaggg aaaaattcaa ggcgtaccca tttgttcatt atggcttgtt
    40261 agacatcgaa cgagatcccc ggaactttgg ctatacatac caaagctttg acgtggttat
    40321 agcaactcat gtcttacata ctactagtaa cctgggagaa accttagagc atgttctgtc
    40381 tctcctggcc cctggtggat tgctcctact taatgaattt acatgtcata ccttatggct
    40441 ggaaatgttt atgggactgc tgggaggtag gcagcagttt gatgacccat tcagacagga
    40501 gaactcactg ctctcagaaa agcagtggga agaggctctt cgagattgtg ggtttgagaa
    40561 ggtagtggct tttcctgagc ctggttcttt agcagaaatt ttgggacaac atatactggt
    40621 ggctcaggtt ccagtacatg ttacataccc acaagactgc tgtatctctg ctatagcaga
    40681 tcaaagtctg atttctaaac ctggtggaaa attctcaact tcataccctg tggtacaaac
    40741 acccgagtca agcctgaccc gcaagaaact tttagcgtta ccattaggga aacgccaaga
    40801 tctactcaga tcttatctag gcgaacaagt tgccaaagcg ctggggattt ctacctcaca
    40861 gctggataca gaacattccc tcaaagacat aggacttgac tctcttatgg caatagtcat
    40921 aaagaaccag gttgaaatgg atctggggtt agttatgcca atagcgaatt ttttacagga
    40981 tatcagcttg gatcagctaa caatgcaagc gctcgagcaa ctgacagtaa tatcttttac
    41041 ccctgaggca tctaataccg cagtgctgga aactgctctc aaacattttg gttcaccgtc
    41101 taagtcacta gtcgaaattc agcctactgg ttcaaagcca ccttttatat gtgtacatcc
    41161 gggtggttta gacgtttctg gttacgctaa tttagcgcgc cacttgacca atgaacaacc
    41221 tgtttacgta ctgcaaccac cagaacttga caattatcga agccttaacg aggaactacc
    41281 gctttttacc accattgaag acgtagccgc tcagtgtgtt aaagccctat gcggtcttca
    41341 gccacaagga ccatatcttt tgggaggttg gtcattagga ggttgtgtag ccttcgagat
    41401 tgctcagcag ctacacaagc aaggtcataa ggtggctctg ctcgccttgc tcgacgttgc
    41461 cgacatattc cattcacctt tagacaatga ttacgcactg gtgtctgggt ttgccagtta
    41521 tttgggagct cgccgcgata aagaactgtt gatcagctac aatgaccttc aggggctaga
    41581 tctggacgag caattgaatc aggtcttaaa acaagcaata atgatgggtg ttgtgccttg
    41641 gaatactggt atttcggaaa ttcgtaattt tttccagatt tacaaaaccg gcactcagac
    41701 ttctttacgg cgattgcaga actacagacc acagatctac ccaaatcaaa tcaccctatt
    41761 tcaagccagt gaagcgttag gagggttaag tgaagttgtc cgcgaaccca tattcaattg
    41821 gggagattgg agcaaattct ctactaaacc gccagagtta catattgttc ctggcaatca
    41881 ttatacgata ctagtcgaac ctcacgttca ggtgctggcg caaaagttga aacactgcct
    41941 tgatcaagtt aagtga
//
