LOCUS       BGC0001886             36704 bp    DNA     linear   PLN 15-APR-2013
DEFINITION  Claviceps purpurea 20.1 WGS project CAGA00000000 data, contig
            scaffold00034, whole genome shotgun sequence.
ACCESSION   BGC0001886
VERSION     BGC0001886
KEYWORDS    .
SOURCE      Claviceps purpurea 20.1
  ORGANISM  Claviceps purpurea 20.1
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Clavicipitaceae;
            Claviceps.
COMMENT     Sequencing was performed by University of Kentucky Advanced Genetic
            Technologies Center
            Guldener U., Oeser B., O'Sullivan D., Tudzynski P. Westfaelische
            Wilhelms-Universitaet Muenster
            Institut fuer Biologie und Biotechnologie der Pflanzen,
            Hindenburgplatz 55, 48143 Muenster, Germany
            birgitt.oeser@uni-muenster.de, tudzyns@uni-muenster.de NIAB,
            Huntingdon Road, Cambridge CB3 0LE, UK
            donal.osullivan@niab.com.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:30:09
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     exon            1..237
                     /locus_tag="CPUR_05422"
     gene            1..2027
                     /locus_tag="CPUR_05422"
     CDS             join(1..237,305..565,654..992,1059..1239,1312..2027)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 360.3; E-value:
                     2e-109)"
                     /gene_kind="transport"
                     /locus_tag="CPUR_05422"
                     /note="CP_05422.1"
                     /product="probable aflatoxin efflux pump AFLT"
                     /protein_id="CCE31569.1"
                     /transl_table=11
                     /translation="MSAMSAMGKPEHGSATTSDLEHRATESSLEKQDVEAAPPGPVKPV
                     DPSPKQSTLKTTLLLASVFLAMFLVAVDRTIISTAIPSITNDYNSLNDVGWYGSIYLLT
                     CCAFQLLFGKLYAMYSARVVLLVSLVIFLAASALCGAAPNSEAFIVGRAISGVGSAGIF
                     AGNIVAIVHTIPLAKRPKIQGLMGAVMGLATIIGPLIGGAFTTRVTWRWCFYINLPFGG
                     LALVAIFFYFKVPNRSPAADLSLKQKILSLDIPGTILLVPAIVCLLLALQWGGQVYDWN
                     NKYIIVLLTLMAVLFVAFIAVQICLPKTATVPPRLLMHRSVVAGFLTTIAIGSAQYIFV
                     YYIPIWFQTVRGVNAVDSGIQLLPLMISFVVASIVGGLLNQRIGYYTALGIFGSSVMAV
                     GAGLMTTWNLEISQGKVIGYQILFGFGMGLAFQTPNLAVQTVLPRPEVPMGIALMFFGQ
                     LLSAAIFVAVGQNILANQLLSRLAGIDGFEHLKSLILSGGVTAVIDAVPEESKHRVLVA
                     YSDALQQVFIVGLAMSCVGVVGTSCMEWKNILKKPAPPAGPPAGAPTESAPVETKAAGH
                     T"
     subregion       1..36704
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001886"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..36704
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     exon            305..565
                     /locus_tag="CPUR_05422"
     exon            654..992
                     /locus_tag="CPUR_05422"
     exon            1059..1239
                     /locus_tag="CPUR_05422"
     exon            1312..2027
                     /locus_tag="CPUR_05422"
     exon            complement(4562..5883)
                     /locus_tag="CPUR_05423"
     gene            complement(4562..6211)
                     /locus_tag="CPUR_05423"
     CDS             complement(join(4562..5883,5989..6211))
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 156.6; E-value: 1.8e-47)"
                     /gene_kind="other"
                     /locus_tag="CPUR_05423"
                     /note="CP_05423.1"
                     /product="related to maackiain detoxification protein 1"
                     /protein_id="CCE31570.1"
                     /transl_table=11
                     /translation="MVDKFLIETDQNEFQPNLWKNGDSDRLPNRCPETQLNVLVVGAGP
                     SGLMTALECWRKGHNVVKILERSNSPVFTGDVIVIGPSALRAFRHWPDMCAELEKSKMD
                     SIMYYRKHNGELILGPTSLGHNDPEYTAAWKGIPFAAPHQIRKDFYRMLLRQVARVGIR
                     VEYGQRVEKYFDDEAAMLGGVITDQGTIMFADLVVAADANRTRSDLLIAGAHTPSRSSG
                     MSVYRTAFPTERALQDEAFRTRWGDAIEKGISHHEFWMGPGMHLGLFISPEFVAFGLTP
                     RDSFLHEGGNEPIESWEPDVDPEEVTKVLNRVPDWNPVIKSLVKNTQRGSIVHWPLLWR
                     NLRREWTSKSGRVVQAGDAAHSSIPASISGGTLALEDAVTLASCLHLSCSSAGSKGAPL
                     GARIYNLLRYQRVSCVQKMSFVNAEGLSGSSMEDAIKENPESVRVRFPRWLYRHDPEAY
                     VYEKYGQAFAHLVEGTDFENTNLPPGHTFEPWTIEQIHKDMMAGKRVADFLDGDWS"
     exon            complement(5989..6211)
                     /locus_tag="CPUR_05423"
     gene            6694..7647
                     /locus_tag="CPUR_05424"
     exon            6694..7647
                     /locus_tag="CPUR_05424"
     CDS             6694..7647
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 55.5; E-value:
                     9.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CPUR_05424"
                     /note="CP_05424.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE31571.1"
                     /transl_table=11
                     /translation="MESTIPAKPDFSNKVFAKDERFWLNYLEGRPTAPKSFFDRIYRYH
                     EEHRGHFGTVHDVGAGNGPYAKELRLKFSHVIVSDIAAENVTLAQERLGNDGFQYRVSR
                     LEDADDIPPGSVDMVFATNVLHFCDQDVAMRALARQLRPGGTFACASFGSAYFADEKVQ
                     EIYTRIGRAGARLLLKTLDDPERLLRAMDRTDGTYNVAPLDEKLFMPGAQRVDLNMPER
                     GMLSPLPPEMEVTERDESHTRPSDVLIQEEEDEWKFSMNIGQIKAHIESFPFGKDVATE
                     LSPLWREMENLVQDRRIDGHWPAKIILATRADASVE"
     exon            8124..8330
                     /locus_tag="CPUR_05425"
     gene            8124..8783
                     /locus_tag="CPUR_05425"
     CDS             join(8124..8330,8529..8783)
                     /codon_start=1
                     /locus_tag="CPUR_05425"
                     /note="CP_05425.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE31572.1"
                     /transl_table=11
                     /translation="MPAPAEVQQATLSKFVDAWKRWNADDFIGLWSDSFTFKVLPLSDG
                     KPTRPRDKVAPLYRNLIGTLTDYKLDVKHIVHDASKGKACIYAVASANAPCGDYKNEQA
                     IFITFSESGDKIESMEEMNDNAFRKEWDPKYHAYHGYGQPPTAKAAAGS"
     exon            8529..8783
                     /locus_tag="CPUR_05425"
     exon            9297..9503
                     /locus_tag="CPUR_05426"
     gene            9297..10034
                     /locus_tag="CPUR_05426"
     CDS             join(9297..9503,9882..10034)
                     /codon_start=1
                     /locus_tag="CPUR_05426"
                     /note="CP_05426.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE31573.1"
                     /transl_table=11
                     /translation="MPAPVEIQQATLSKFIDAWKRWNADDFIGLWSDSFTFQVLPFSDG
                     KPTRPRDMIAPMYRNFIETLTNYKAIFIAFSESGDKIERLEEVNDNAFRKEWDPKCHAY
                     WGYGQPPKAKAVAGS"
     exon            9882..10034
                     /locus_tag="CPUR_05426"
     gene            10660..12024
                     /locus_tag="CPUR_05427"
     exon            10660..12024
                     /locus_tag="CPUR_05427"
     CDS             10660..12024
                     /codon_start=1
                     /locus_tag="CPUR_05427"
                     /note="CP_05427.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE31574.1"
                     /transl_table=11
                     /translation="MASTTGTEATPSRISLSQDHLGILHDVKVNTASIEIANSLLQKNH
                     EEWHMFFRDRAGHNHISHSILTCLALGGSPEDIQRAYDDGLEIQRPMPPLDDALVARLG
                     DDNVMYESLGSISQYRSFLAYFQHHMEEHGWKATVTKYLFSHTKLSEKMLARMYEGAYH
                     PVIHLGLGFEFQQPAIVAEALAQAAAHDDSNLYTYFIACEEESEIAYPLQQAKTLLQIM
                     ADASSSKTIRNAPHWEDYGNKMRDGVLGRACRETANVASKFVIRKTPESLRRRTAEMID
                     TCAYVAASSQRSGRKRKIDFFYMHMVTSSLFFSVIGEQDWIPLNDRIRMVEWKARLDVA
                     WYVVCGCADIQQLALTAYNDPVTDGMGWEELYAAVVKEHDDGHVSKMIRALKNGQEAAR
                     PFENGPYRNAFPLHGDMWLKAARMTLGTTTGCDEDTKFVMFTGFDIPWETRPDLQ"
     protocluster    10968..36704
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[30967:36704]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      30968..36704
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    10968..36704
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     exon            complement(12584..12937)
                     /locus_tag="CPUR_05428"
     gene            complement(12584..13230)
                     /locus_tag="CPUR_05428"
     CDS             complement(join(12584..12937,13046..13143,13206..13230))
                     /codon_start=1
                     /locus_tag="CPUR_05428"
                     /note="CP_05428.1"
                     /product="probable scytalone dehydratase"
                     /protein_id="CCE31575.1"
                     /transl_table=11
                     /translation="MSKTPSYEDATACQAALFEWAESYDLKDWNRLSKCIAPTLQIDYR
                     AVFGQFWEAMPADEFVGMISSPGFLGNPLIKTQHFVGMTRWTQTSEDSVTGRHQMRVAH
                     QKYADAQMKEVVLKGHGHGGATTWFRKVDGDWKFAGIEPEIRWAEFDLDKIFAE"
     exon            complement(13046..13143)
                     /locus_tag="CPUR_05428"
     exon            complement(13206..13230)
                     /locus_tag="CPUR_05428"
     exon            13652..13984
                     /locus_tag="CPUR_05429"
     gene            13652..14695
                     /locus_tag="CPUR_05429"
     CDS             join(13652..13984,14145..14471,14561..14695)
                     /NRPS_PKS="Domain: PKS_KR (14-173). E-value: 1.8e-11.
                     Score: 36.1. Matches aSDomain:
                     nrpspksdomains_CPUR_05429_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.5; E-value: 1.5e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CPUR_05429"
                     /note="CP_05429.1"
                     /product="probable tetrahydroxynaphthalene reductase"
                     /protein_id="CCE31576.1"
                     /transl_table=11
                     /translation="MSETHIPYRLDGKIALVTGSGRGIGAAMAVELGRLGAKVVVNYVN
                     SVESAEKVVDEIKGLGSDAVAIQADVRQVSQIVELMDKAVKHFGGLDIVCSNSGVVSFG
                     HFGDVTEEEFDRVFSLNTRGQFFVAREAYRHLNNGGRIILMSSNTAKDLSVPKHSLYSG
                     SKGAIDSFVRIFSKDAGDKKITVNAVAPGGTVTDMFHSCSQHYIPGGDKYTAEERQAMA
                     AHASPLTRNGFPLDIAKVVCFLASDEAEWVNGKVLTLDGGAA"
     aSDomain        join(13694..13984,14145..14330)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_05429_PKS_KR.1"
                     /evalue="1.80E-11"
                     /label="CPUR_05429_PKS_KR.1"
                     /locus_tag="CPUR_05429"
                     /protein_end="173"
                     /protein_start="14"
                     /score="36.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGSGRGIGAAMAVELGRLGAKVVVNYVNSVESAEKVVDEIKG
                     LGSDAVAIQADVRQVSQIVELMDKAVKHFGGLDIVCSNSGVVSFGHFGDVTEEEFDRVF
                     SLNTRGQFFVAREAYRHLNNGGRIILMSSNTAKDLSVPKHSLYSGSKGAIDSFVR"
     exon            14145..14471
                     /locus_tag="CPUR_05429"
     exon            14561..14695
                     /locus_tag="CPUR_05429"
     gene            17856..18632
                     /locus_tag="CPUR_05430"
     exon            17856..18632
                     /locus_tag="CPUR_05430"
     CDS             17856..18632
                     /codon_start=1
                     /locus_tag="CPUR_05430"
                     /note="CP_05430.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE31577.1"
                     /transl_table=11
                     /translation="MASYAVLGATGNCGSALIQLLLQRPDASIHAFCRNKPKLIGLLPE
                     IEKSERVTIYQGSIKDTDLLTACLRGRRAVFMVLSSNINEPGFRVGRDANKAVIEVLRT
                     LHREDSGSTGPPPKIILLSSATLDDTLSRKTPYLLRQILHMSASHIYNDLAETEKLLRA
                     EQEWLTTVFVKPGALSVDEQRGHALSFVESDNPVSYLDLAAAMIEAADDTTDKYDMKNI
                     GVVNTNGAARFPTGTPLCIATGLLRHFVPSLHPYLP"
     gene            19228..20751
                     /locus_tag="CPUR_05431"
     exon            19228..20751
                     /locus_tag="CPUR_05431"
     CDS             19228..20751
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 334.3; E-value:
                     2.3e-101)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CPUR_05431"
                     /note="CP_05431.1"
                     /product="related to phenol 2-monooxygenase"
                     /protein_id="CCE31578.1"
                     /sec_met_domain="DAO (E-value: 5.4e-12, bitscore: 35.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANSSVYADVIVVGAGPVGLFVACELALHDVSVIVLERDADSDNV
                     WKKGLLGGRGMYKPALEAFYRRGLLADLLYDEKRVTYLEKTSGFQYAGHFGGRLLNANA
                     VDFSRFKYHLPGPTFLPAKTTIADIECELSKRATECGVRIVRGVEISRVEDEGDEVTVW
                     ADNQSFKSNWLVACDGGKSTIRKAAGFQFTGTDSELTCYIAVCDVDKPELLGKGMKPTD
                     AGMYIVSGPRHLYVMDFDTTFDRSQTVTKEHLERVLQRVSGTSVKIEALELVSTFTDRC
                     KQTTQYRKGRILLAGDSAHIHSPLGAQGLTTGIADAFNLGWKLASTVKGYASADLLDTY
                     QRERQPEGAWTLDWSRSQVVIMRPDPAGKAISRLVTEYMATDDGTTFFVNKIWGISRRY
                     DLVGAQAHPLVGCSVPDFQFEDGSYLGSKLHEGKFMTVDFSGSKLLEEATDLVQPWVGY
                     LSCSVKDRLGMNALLLRPDGVVAWVAEDEVKVDSWKAALSQWIVLPGEA"
     exon            complement(21167..21712)
                     /locus_tag="CPUR_05432"
     gene            complement(21167..22980)
                     /locus_tag="CPUR_05432"
     CDS             complement(join(21167..21712,21965..22486,22645..22980))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 81.2; E-value:
                     1.4e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CPUR_05432"
                     /note="CP_05432.1"
                     /product="o-methyltransferase that catalyse the methylation
                     of nor-rubrofusarin resulting in formation of rubrofusarin"
                     /protein_id="CCE31579.1"
                     /transl_table=11
                     /translation="MEKLAALKKLPSILRPLLTSKSSYHRVPSDRPTIMDAATSEQLHG
                     LTNRLLTEVNALVSSYSSIDCQHPFLAAACESQNDGSEARSNILSSLSEIEAIVRGPKE
                     FLENIAIQCEMLGSIQWLGEFQILACIPLSQEVPIQDVANLSNVPEQQLAQMIGLTARC
                     GFLIEPRRGYVAHTPLSASFVTNPSHLDAAMFLAEQAAPAALKSATATQRFTESHTNNE
                     TAFSLATTTKVPFEAAQEQSPRLSRQWAAYLHHAGGLPEDHVLADAMAKLHWSNISKAG
                     GQVVEVGAFLAAKPLARLFPQLRFLVQLPAGASSCESILCDPSDPIKPGQISIANRVPG
                     SPQSVTNAAVYVLHLPSSVPSQILTELQVHLPALRMSNGVMLIMSGRVLPGQDEPIRAR
                     HAAVAHARGLIMYQMSNEVEMDLSSLLQMLDTVRDSTGKLVLVHKLRSCSGMTVAVVVK
                     YQLMAGGAS"
     exon            complement(21965..22486)
                     /locus_tag="CPUR_05432"
     exon            complement(22645..22980)
                     /locus_tag="CPUR_05432"
     gene            24588..26054
                     /locus_tag="CPUR_05433"
     exon            24588..26054
                     /locus_tag="CPUR_05433"
     CDS             24588..26054
                     /codon_start=1
                     /locus_tag="CPUR_05433"
                     /note="CP_05433.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE31580.1"
                     /transl_table=11
                     /translation="MDHSIGGRNCQSGGTTASAPRSTGSDEFPSKLRETCHACSLSKVR
                     CSKEKPSCSRCAKRGVPCEYIVTKRPGRKRDPTKSAGLTSSHCKSFDAATAAPNNTNAN
                     CAWLEDVLLTDMGGSGGGSTGHAYLDSTQTDTGSPMLWPLMANDGADIAGDMSDFLMPL
                     ITPLSCTFTARTPDFLSAAAEFSAPISPPNNHDDKNNNQSMQDGSNVMQLLLPDDVHGG
                     HAAENAAQEAPSVDFHSSCSSRSLSSVPESFLSSKIASNSDFGSASSSCECLIKALDIM
                     AKVSSTDLAVTPDTPSTRRNSVQDEAVVAGHDQTSPLLHATFMANKQTIEALSNMLHGS
                     CQENVYLLTCMSMIVFKVLRRYEMAAGQSISAGVLDMHEAARPRHGDLDRDSLRRAAAQ
                     LVLGELHLVQQLVSRLSRRLQLSMDKTPNDGADSELSDSTLATRVFTLDEDDKADTSAF
                     SAATLSQMDHDLRKGLARLSSNIINMLRRL"
     exon            complement(26279..26330)
                     /locus_tag="CPUR_05434"
     gene            complement(26279..27035)
                     /locus_tag="CPUR_05434"
     CDS             complement(join(26279..26330,26421..26617,26859..27035))
                     /codon_start=1
                     /locus_tag="CPUR_05434"
                     /note="CP_05434.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE31581.1"
                     /transl_table=11
                     /translation="MKMGMAKHSPRNKEYLCLTICGYRKEGMSEEAYRNHMVNVSAPMT
                     KDLMVKYGIRRWTQIHNQNATRALMAELFDPQMCRLADFDCFSQVVFDNIEDYKRMKQD
                     PWYKKHLMHDHEMFADTKRSMMTIGWIKEFVVDGKAV"
     exon            complement(26421..26617)
                     /locus_tag="CPUR_05434"
     exon            complement(26859..27035)
                     /locus_tag="CPUR_05434"
     exon            27943..28009
                     /locus_tag="CPUR_05435"
     gene            27943..28543
                     /locus_tag="CPUR_05435"
     CDS             join(27943..28009,28086..28543)
                     /codon_start=1
                     /locus_tag="CPUR_05435"
                     /note="CP_05435.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE31582.1"
                     /transl_table=11
                     /translation="MLRGFAPTGVHVVALASGVFLSGAMFSVSAIMIPTLLDTNKEPAG
                     LTTQWARLYHYGSVLMPSMSVAIAAVYGFASTQYRQSPQGMRCLAAGALTLAIAPYTWL
                     AMIPTNNALFAMAASAPGFAGMQDANEKARDLVMKWVVLHSIRSILPLAGAIMGFTGIS
                     SGQEGVVGSAN"
     exon            28086..28543
                     /locus_tag="CPUR_05435"
     exon            complement(28784..29554)
                     /locus_tag="CPUR_05436"
     gene            complement(28784..29814)
                     /locus_tag="CPUR_05436"
     CDS             complement(join(28784..29554,29653..29814))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     145.1; E-value: 3.1e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CPUR_05436"
                     /note="CP_05436.1"
                     /product="uncharacterized protein"
                     /protein_id="CCE31583.1"
                     /transl_table=11
                     /translation="MAGDKGGYRQINSSLNICAFEDYLKSQTDNLPELPDVEQITPRVL
                     RVLGQNPGKFTYQGTNTYIVGTGKHRLIVDTSGGEIEWAELLESTLSSLNISLSHVLLT
                     HWHGDHTGGVPDLLRIYPHLEHDIYKNEPESGQQDIVDGQIFRVEGATVRALHVPGHSD
                     DHMCFILEEEQAMFTGDNILGHGTSAVEDLGTFMASMQRMLDQRCLTGYSAHGAVIADL
                     PGKIRTELANKRRREKQILLALGRVRQRRQKSITVEDLVTEIYGESMDESTRTLALTPF
                     TDEVLRKLAGDFKVAFEVRAGKRRWYSVE"
     exon            complement(29653..29814)
                     /locus_tag="CPUR_05436"
     exon            30968..31323
                     /locus_tag="CPUR_05437"
     gene            30968..36704
                     /locus_tag="CPUR_05437"
     CDS             join(30968..31323,31450..32854,32952..35345,35433..36704)
                     /NRPS_PKS="Domain: SAT (30-272). E-value: 2.2e-53. Score:
                     173.1. Matches aSDomain: nrpspksdomains_CPUR_05437_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (409-842). E-value:
                     1.4e-142. Score: 467.4. Matches aSDomain:
                     nrpspksdomains_CPUR_05437_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (942-1245). E-value: 7.1e-88.
                     Score: 286.6. Matches aSDomain:
                     nrpspksdomains_CPUR_05437_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1338-1657). E-value: 5.8e-112.
                     Score: 366.0. Matches aSDomain:
                     nrpspksdomains_CPUR_05437_PT.1"
                     /NRPS_PKS="Domain: ACP (1743-1804). E-value: 1e-10. Score:
                     33.7. Matches aSDomain: nrpspksdomains_CPUR_05437_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 169.2; E-value: 2.8e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CPUR_05437"
                     /note="CP_05437.1"
                     /product="polyketide synthase that catalyse the
                     condensation of one acetyl-CoA and six malonyl-CoA
                     resulting in formation of nor-rubrofusarin"
                     /protein_id="CCE31584.1"
                     /sec_met_domain="itr_KS (E-value: 1.2e-156, bitscore:
                     511.8, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2e-88, bitscore: 286.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-10, bitscore:
                     31.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIYTPNKSSDANSESSSLRVIFFGNELPNDDLQTHFRRLHTRSK
                     DKNHPLLARFIDEATLVLKEEISALSTDLGRLIPTFETVLQWSEDANASLREGLLCGAI
                     DGVLLVVLQLASYICYHEILTYDKEECVHIALTGLGIGLLSSTAVSLAPTPSHLPLAGA
                     DVVRLAFRLGIHVLGVSELLEARDVSGKPASWAYLVQIADSDAAQAELDLLYGNAESSA
                     NSNKIIISAVSQTSIVASGPPSRLKLLFNKSPLFRNARSTALPVFGGLCHAAHIYGEND
                     ARSIVECASLNTVTENCTPLLPIYSTSTGNPYLANNATETFECVISELLRKQICWDNVI
                     NGIRERINYSGASAAAVDHFGNSASLHDLEVALKSVLHESQVTLTNILTMSCVPPPKEI
                     SPRSTGLSKLAIVGMACRLPGGATDTEKFWDILVKGLDVSRKVPADRFDIETHYDPTGK
                     QMNKSMTQYGCFIDEPGLFDAPFFNMSPREAQTTDPQMRLALVTAYEALEQAGYVGNRT
                     NSTKLERIGTYYGQAADDYREVNQGQEVSTYYIPGGCRAFGPGRINYFFKFAGPSYSID
                     TACSSGLAAIEVACQGLWNGVIDTAVAGGVNVLTNPDGFAGLCNGHFLTKGHNACKTWD
                     STADGYCRADGIGSLVIKRLEDAEADNDNILGIILGAGTNHSAEAVSITHPHAGHQAYL
                     SRQVLRQAGVDPLDVSYVELHGTGTQAGDYEEMQGILDVYAPLTKRRSADNPLHIGAVK
                     ANLGHGESVAGTTALMKVLLMFREQAIPPHIGIKGEINPKIPKDLAKRNLHIPMNLESW
                     RRRSDKKRLAVVNNFGAAGGNTTMVLEEAPIRCIEEMDPRQTHVISVSAKTKNSLVGNI
                     ERLIAYLDSNPDTSLADLSYTTMARRYQHSWRVAMAPSTMKDLKKQLSAYLEKIDLVKP
                     AGKSGPPTVAFTFTGQGASHKSMNLALYHDVPSFRDYIQRLDAIAQGQGFPSFIPAIDG
                     SHPQDHQHSAVVTQLALVCSEMAMAQYWFSLGIKPDVVIGHSLGEYAAMHVAGVISASD
                     TIFMVGRRAQLLQEKCKLGSHSMVAVRASLEEIKQNTSSTDSDAEFTIACINGPTDTVL
                     SGTKNAIDAVSKTLEQAGFRCTKLDVAFAFHSDQTDPILDEFEDIVKASVSFQEPKMPV
                     ISPLLGKVVFDGKTLNANYVRRATRETVDFISALHNAQKMSTISEDTVWIEVGPHAVCT
                     NMIKKILPATKLALPSMRRDADNWKTVSDSLAALHSSGVEIFWNEFHRPFERRLRLLDL
                     PTYSWNNQTYWLQYQGDWCLTKGNGFYGTLGQGSGSAASSSSPSLLASSVSNLHTSTVQ
                     CIIEETIDGTNGTVVMQSDLMQPDLYTAAEGHRMNDCAVVTSSIHADIAFTLAEYMLPK
                     LLPASKKLKAIIQDLVVTKGLVANHDRNSPQLFRVTATTTDILHHGLDLTWQNVDNDGT
                     VHEPFATAKITFGDPEQWLSSWSPMVHLVQSRVEALEALVADGTANRFSRAMAYGLFAK
                     NLVDYSEKYRGMQSVIMHGLEGFANVRLTDKESGNWTVPPHFIDSVAHLAGFIMNCSDA
                     INTVDNYCVTPGWKAMQFAKPLTPGARYQSYVKMIPQADNSGTYLGDVYIMQDGDIIGK
                     VWGIEFRRYPRLLLSRFFSAPGKSSTTTTTKASVSAPVKSKPVETKLSAASKPPTVAQT
                     GIPPEQKPAPEVQPVTTNSPATAAAAPASTQAADTDTVSAKALRLIANEAALDLSQLED
                     DAGFAELGIDSLMSLVIAEKFKIELDVKVGGSLFLDYPTIGDLRKWLEEYYS"
     aSDomain        join(31058..31323,31450..31909)
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_05437_SAT.1"
                     /evalue="2.20E-53"
                     /label="CPUR_05437_SAT.1"
                     /locus_tag="CPUR_05437"
                     /protein_end="272"
                     /protein_start="30"
                     /score="173.1"
                     /tool="antismash"
                     /translation="DDLQTHFRRLHTRSKDKNHPLLARFIDEATLVLKEEISALSTDLG
                     RLIPTFETVLQWSEDANASLREGLLCGAIDGVLLVVLQLASYICYHEILTYDKEECVHI
                     ALTGLGIGLLSSTAVSLAPTPSHLPLAGADVVRLAFRLGIHVLGVSELLEARDVSGKPA
                     SWAYLVQIADSDAAQAELDLLYGNAESSANSNKIIISAVSQTSIVASGPPSRLKLLFNK
                     SPLFRNARSTALPVFGGLCH"
     exon            31450..32854
                     /locus_tag="CPUR_05437"
     aSDomain        join(32321..32854,32952..33716)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_05437_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.40E-142"
                     /label="CPUR_05437_PKS_KS.1"
                     /locus_tag="CPUR_05437"
                     /protein_end="842"
                     /protein_start="409"
                     /score="467.4"
                     /tool="antismash"
                     /translation="AIVGMACRLPGGATDTEKFWDILVKGLDVSRKVPADRFDIETHYD
                     PTGKQMNKSMTQYGCFIDEPGLFDAPFFNMSPREAQTTDPQMRLALVTAYEALEQAGYV
                     GNRTNSTKLERIGTYYGQAADDYREVNQGQEVSTYYIPGGCRAFGPGRINYFFKFAGPS
                     YSIDTACSSGLAAIEVACQGLWNGVIDTAVAGGVNVLTNPDGFAGLCNGHFLTKGHNAC
                     KTWDSTADGYCRADGIGSLVIKRLEDAEADNDNILGIILGAGTNHSAEAVSITHPHAGH
                     QAYLSRQVLRQAGVDPLDVSYVELHGTGTQAGDYEEMQGILDVYAPLTKRRSADNPLHI
                     GAVKANLGHGESVAGTTALMKVLLMFREQAIPPHIGIKGEINPKIPKDLAKRNLHIPMN
                     LESWRRRSDKKRLAVVNNFGAAGGNTTMVLEEAP"
     aSModule        32321..36689
                     /complete
                     /domains="nrpspksdomains_CPUR_05437_PKS_KS.1"
                     /domains="nrpspksdomains_CPUR_05437_PKS_AT.1"
                     /domains="nrpspksdomains_CPUR_05437_PT.1"
                     /domains="nrpspksdomains_CPUR_05437_ACP.1"
                     /iterative
                     /locus_tags="CPUR_05437"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       32801..32848
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_05437_0001"
                     /evalue="7.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="CPUR_05437"
                     /protein_end="585"
                     /protein_start="569"
                     /score="18.1"
                     /tool="antismash"
                     /translation="GPSYSIDTACSSGLAA"
     exon            32952..35345
                     /locus_tag="CPUR_05437"
     CDS_motif       33090..33128
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_05437_0002"
                     /evalue="4.80E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="CPUR_05437"
                     /protein_end="646"
                     /protein_start="633"
                     /score="10.3"
                     /tool="antismash"
                     /translation="WDSTADGYCRADG"
     CDS_motif       33321..33368
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_05437_0003"
                     /evalue="3.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="CPUR_05437"
                     /protein_end="726"
                     /protein_start="710"
                     /score="10.1"
                     /tool="antismash"
                     /translation="YVELHGTGTQAGDYEE"
     aSDomain        34017..34925
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_05437_PKS_AT.1"
                     /evalue="7.10E-88"
                     /label="CPUR_05437_PKS_AT.1"
                     /locus_tag="CPUR_05437"
                     /protein_end="1245"
                     /protein_start="942"
                     /score="286.6"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="FTGQGASHKSMNLALYHDVPSFRDYIQRLDAIAQGQGFPSFIPAI
                     DGSHPQDHQHSAVVTQLALVCSEMAMAQYWFSLGIKPDVVIGHSLGEYAAMHVAGVISA
                     SDTIFMVGRRAQLLQEKCKLGSHSMVAVRASLEEIKQNTSSTDSDAEFTIACINGPTDT
                     VLSGTKNAIDAVSKTLEQAGFRCTKLDVAFAFHSDQTDPILDEFEDIVKASVSFQEPKM
                     PVISPLLGKVVFDGKTLNANYVRRATRETVDFISALHNAQKMSTISEDTVWIEVGPHAV
                     CTNMIKKILPATKLALPSMRRD"
     CDS_motif       34251..34373
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CPUR_05437_0004"
                     /evalue="1.80E-17"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="CPUR_05437"
                     /protein_end="1061"
                     /protein_start="1020"
                     /score="55.4"
                     /tool="antismash"
                     /translation="GIKPDVVIGHSLGEYAAMHVAGVISASDTIFMVGRRAQLLQ"
     aSDomain        join(35205..35345,35433..36248)
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_05437_PT.1"
                     /evalue="5.80E-112"
                     /label="CPUR_05437_PT.1"
                     /locus_tag="CPUR_05437"
                     /protein_end="1657"
                     /protein_start="1338"
                     /score="366.0"
                     /tool="antismash"
                     /translation="TSTVQCIIEETIDGTNGTVVMQSDLMQPDLYTAAEGHRMNDCAVV
                     TSSIHADIAFTLAEYMLPKLLPASKKLKAIIQDLVVTKGLVANHDRNSPQLFRVTATTT
                     DILHHGLDLTWQNVDNDGTVHEPFATAKITFGDPEQWLSSWSPMVHLVQSRVEALEALV
                     ADGTANRFSRAMAYGLFAKNLVDYSEKYRGMQSVIMHGLEGFANVRLTDKESGNWTVPP
                     HFIDSVAHLAGFIMNCSDAINTVDNYCVTPGWKAMQFAKPLTPGARYQSYVKMIPQADN
                     SGTYLGDVYIMQDGDIIGKVWGIEFRRYPRLLLSRFFS"
     exon            35433..36704
                     /locus_tag="CPUR_05437"
     aSDomain        36507..36689
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CPUR_05437_ACP.1"
                     /evalue="1.00E-10"
                     /label="CPUR_05437_ACP.1"
                     /locus_tag="CPUR_05437"
                     /protein_end="1804"
                     /protein_start="1743"
                     /score="33.7"
                     /tool="antismash"
                     /translation="ANEAALDLSQLEDDAGFAELGIDSLMSLVIAEKFKIELDVKVGGS
                     LFLDYPTIGDLRKWLE"
ORIGIN
        1 atgtccgcca tgtccgccat gggcaaaccc gaacacggca gcgcaacgac cagcgaccta
       61 gaacaccgag ccaccgaaag ctcacttgag aaacaagatg tcgaggccgc acctccaggg
      121 cctgtcaagc ccgtcgaccc gagcccgaag cagtcaactc tgaaaacgac acttctcctg
      181 gcttctgttt tcttggccat gttcctcgtg gccgtggaca gaacaatcat ctcaacggta
      241 cggcacacct ggagaggaaa cattatacct tttgacgcaa gctaactcgg ttcattcgca
      301 acaggccata cccagcatca caaacgacta caactcgcta aacgatgttg gttggtacgg
      361 cagtatatac ctattgacct gctgcgcgtt ccagctgcta tttggaaagc tctacgccat
      421 gtattctgcc agagtggtcc tcctcgtcag cctcgtcatc tttttggctg cttctgcgct
      481 ttgcggcgcg gcgcccaact cagaggcctt catcgtcggc cgagcaatct ccggagtcgg
      541 ctctgccggt attttcgcag gaaatgtacg cttcctccca tttttttggt caacggtcta
      601 tagtttatgt ggcctgcggc tcgctaactc gactttcttt ttcttctact cagatcgttg
      661 ccattgtcca cacaatccca ctcgcgaagc gtccaaaaat ccagggcttg atgggcgcag
      721 tcatgggact cgctaccatc attggccctt tgattggcgg tgcctttact acaagagtga
      781 cctggaggtg gtgcttctac atcaatctcc cctttggtgg tttggccctg gtggctattt
      841 tcttctactt caaggttccg aatcgaagcc cggcagcaga cctatcgctg aaacagaaga
      901 ttctgagctt ggatattccg ggcaccatcc tccttgtgcc tgccattgtg tgtcttcttc
      961 tagcgcttca atggggtggc caagtatacg atgtaagttt accatgagaa agctctgttc
     1021 ctttcacgta tagaccgcca gtgctgacat gactccagtg gaacaacaaa tacatcattg
     1081 tgctgctgac gctcatggcg gtgttgttcg tcgcattcat agccgttcag atatgtctgc
     1141 ccaagacagc aaccgtgcca ccgcgtcttc tcatgcatag aagcgtggtt gctggctttc
     1201 ttaccaccat cgccattggg tctgcccaat acatctttgg tacgtgcaaa cctttccatt
     1261 cctgagcttc gtgttccatc gacgtgcttt cgctaatcga ccgacttcca gtttattata
     1321 tccccatctg gttccagacc gtccgaggtg tcaacgccgt agattctgga atccagctcc
     1381 tgcctctcat gatttcattt gttgtcgcct ccattgtcgg cggcctattg aaccaaagaa
     1441 tcggatacta cacagcgctc ggaatcttcg gctccagtgt catggctgtg ggcgccggcc
     1501 tcatgaccac ctggaacctc gaaatatccc aaggcaaagt gatcggatac cagattcttt
     1561 tcggcttcgg catgggtctt gccttccaga ctcccaatct cgccgtccag actgtgttgc
     1621 ctaggcccga agtccccatg ggcatcgcgc tgatgttctt cggccagctg ctcagtgcag
     1681 ccatctttgt ggctgtgggt caaaacatac ttgccaatca actgctttcc agactcgccg
     1741 gtattgatgg cttcgaacat ctcaagagcc tcatcttgtc gggaggtgtg acggctgtga
     1801 ttgatgcagt gcccgaggag tccaagcaca gggttctggt ggcctacagt gatgccttgc
     1861 agcaggtgtt cattgtcgga ctggccatgt cttgcgtcgg cgtcgttggc acatcctgca
     1921 tggagtggaa gaatattctc aagaagcctg cgcctcccgc tggtcctccg gccggtgctc
     1981 cgaccgagag tgcgcctgtt gagaccaaag cagctgggca tacataggtg gaggtcgagg
     2041 gccgaggcga tggtaattgt atacgaggag gaataatctc gagggtcgtg ttttcatgat
     2101 ttgatatccc aaaatggcta aagtgaatac ccaaatagcg ctcagtgcat ttaagcgacg
     2161 gagatcagtg atggaatatt ttatttaatg gaaatcatgt atatagctgg cacatacctt
     2221 ggtatgtctg cgcgacaatg agaatgtaat tgctcaatga tcattgcgat gtgactgcac
     2281 aaaagcaggt gcaacttgct acattgtctt tgtaactagg tacaagcgta ggtacgtaga
     2341 caggaacgta gaaaagccac tttgcatgct gaagatgcgc aattgggcat caatctatag
     2401 agttttcacg ggataaacag atggcgcacg tggatgaaag caattgacgc gatgcgacgc
     2461 ccgtgacttc gtgttttatt ttatttttcc gccttctgat gaagaaatga agggtgagat
     2521 gctcggaaac caacattttt cgtcttgttg ggagacctta atgagtacat acctcagcaa
     2581 ctgcctaatc accaccctaa gaatagccag accggcccaa gacaacttct ttttagcgct
     2641 ccaatttcca tgaaaattac tataagtaat tcgtcatacg tttatgatca aaacttgagt
     2701 cttatattta atccctcatc ccttccagca cgtgctcagc acctcatgga tgatggacga
     2761 tgatagagga ggtacaaagc gagatgtggt cagccacagc atgattggct gcgctacaga
     2821 cgaaccatac ctacttaggc aacttggggt ggtgattagg cagttgttga ggtgctcatt
     2881 aaggtctcac ccgtcttgtt ctccctcgtt acctatttgg gacaagtctg tttcctcggc
     2941 ttgattagcc caccataaaa ctcctccttt tcacaacaca aaaaaccgcc ctctcagaaa
     3001 catccatcat tttcccatcc acctccatct catcaatcaa tccatctcta cacgacgact
     3061 caatctcaaa gatgcctcga atgttcacgc acactcaatg gaaggggcga ggatcgagag
     3121 acatctcctc ccagagccaa cacgctcctc cagaaacgca ccaggccagg atcccccccc
     3181 ccccccatca gactcgctcc ccgtgctctc gcctcttggg cactgggcag tagtgtctcg
     3241 agcatccaat gaaatgcttc ggcgaatagt ttgaatttaa atggtgatgt gtgcatccca
     3301 aaagggagtg cttggattca tctcacacaa ctgttcccaa accgagaatt gcctcccgtt
     3361 tgggttgcac accgcaccat ttatatttat cctatttgcc gaagcattgc actgcatggt
     3421 cgaggcacta ctacccaacg tcctgctgcg acattacctc gatgacttca ttttcgtcct
     3481 ccgcgcggga gatatccagc gagcactgtc acgacctgca ctacataacc tcaatcaagc
     3541 tgcagacgtg caacttggtc acttgaccta ttgggtggaa cgggtggtta tgcgtttctc
     3601 acaagcacca ctcatgcacg acacctggcg ggcgattacc gacttcctgg gtttgtatcg
     3661 caacgaatcg atggacgccg agagcacgtg cgtggatgtg ctccgagtcg agttcgaggt
     3721 cgatacgatc aacatgcaag cgcgcctgtc gagcaagaag gtggcgaagg ccaatacata
     3781 gcctgatcac tagtggcgct caccctgact acggtgaccc tccgcagatt caggggctca
     3841 caggcttcct caacttctgt acggcggtaa tacccattgg gcttgcgtgc caaagccgtg
     3901 accagtttca agcactcggc cgttggtcgt caggcgctgt cgaccgatac tacagaacgg
     3961 atcaacagca cctattcatg ctgcagcgac ggttgaaacc aaaacaacca acagcattgt
     4021 aatttgggcg tgagcttggg gcctcccttc tcgcacgaat ggcctgctac aacgacccgc
     4081 ggcgctttct tagagccccg ggctggaagc ttgtcttcgc gaagagctcc cacggtgact
     4141 ctctcgccta cgaagacctt ctccggtttc tggcaggcct atatgcggct cacgcctccc
     4201 caaataaagc gtcttacgaa ctatactaca agaccctctc tctccctctg tctccctctc
     4261 tctccctctg tctccctctc tctccctctc tctggagtct gcatcggtat tggcgtggtg
     4321 aataaatcga ccccaaacgc atgcccacac tgcacctctt tttgctgcaa gatctacttc
     4381 gcattttcca tgagtcaagt aaagatacat gcatagtcct gtcaccatct cgaatgctta
     4441 tactattcac acgcgctcaa gctatgtgtc ttacgacctt acgagtatgt tccacgccaa
     4501 tgtgggcgac caaaaacggc ttagcgtggc ggtacgcatg ttcagaactt aggcttcatc
     4561 ctcacgacca atctccatcc aaaaaatccg caactctctt cccggccatc atgtccttgt
     4621 ggatctgctc aatcgtccaa ggctcaaagg tatgtcccgg gggaagattc gtattctcaa
     4681 agtccgtacc ctcgaccaaa tgcgcgaacg cctgcccata cttctcgtag acgtacgcct
     4741 ctggatcgtg cctatacaac cacctcggaa agcggacgcg aacactctcg gggttctcct
     4801 tgatggcgtc ttccatggaa gagccgctga ggccttccgc gttgacaaac gacattttct
     4861 gcacacagct cacgcgctgg taccggagga ggttgtagat tcgtgcgccc agaggagcgc
     4921 ccttggagcc agcggacgag catgagaggt gcagacacga ggcgagcgtc acggcatcct
     4981 cgagagctaa cgtaccgccg ctgattgatg cagggatgct actatgcgca gcgtcgccgg
     5041 cttggacaac gcgaccactc ttggatgtcc actcgcggcg tagattgcgc cagagcaacg
     5101 gccagtgcac gatgctgcct ctttgggtgt ttttcacgag gctcttgatc acggggttcc
     5161 agtctgggac gcggttaagc actttggtga cttcttccgg gtcgacgtct ggctcccagg
     5221 actcaatggg ctcattgccg ccctcatgca ggaaggaatc acggggcgtg agtccaaagg
     5281 cgacgaactc gggtgagatg aagagaccga gatgcatgcc gggccccatc cagaattcat
     5341 gatgcgatat ccccttctca atggcgtcgc cccatcgcgt gcgaaaggcc tcgtcctgaa
     5401 gagcccgctc tgttgggaac gcggtgcggt acacagacat accactcgaa cggcttggcg
     5461 tgtgcgctcc agcgattaac agatccgatc gagtcctgtt cgcgtcagca gcgacgacaa
     5521 ggtctgcgaa catgatggtg ccttggtctg tgatgacgcc tccaagcatc gctgcttcgt
     5581 cgtcaaagta tttctccaca cgctgtccgt actcgactcg gattcctacc ctggccactt
     5641 gtcgcagaag catgcggtag aagtccttgc gaatctggtg cggtgccgca aaggggatgc
     5701 ccttccatgc agcggtgtac tcggggtcgt tgtgtccaag agaggtcggc ccgaggatga
     5761 gctcgccgtt gtgcttgcga taatacatga tgctgtccat cttgcttttc tctagctctg
     5821 cacacatgtc gggccaatgg cggaatgctc gaagggcgga tgggccgatg acgatgacgt
     5881 cgcctggtac gcaaggggca cattggccgg ttgttagcgg tgggaggctt tttcgcgatt
     5941 acgattcatc aactctctcc gtttatcggt tcagtgacgc aaactcacca gtgaacactg
     6001 ggctgttact tctctcgagg attttgacaa cattatggcc ttttctccag cattccagcg
     6061 ctgtcatcaa tccggatggt cctgcaccca cgacaagcac attgagttga gtttcgggac
     6121 accggttggg gagtcgatcg gagtcaccat tcttccacaa attgggttga aactcatttt
     6181 ggtctgtctc gatgagaaat ttgtctacca tggtggaatt actttttgtt tgcacagtat
     6241 ggatcgtcta ctactctacg ggcggaagca gttgtccctg cagaggggcc cgcgctgtta
     6301 agagtctacc aggagatacg cggaacaatg aggcgctatt tccgtattaa gctattgttt
     6361 tgtgacacgt tcgggtatca ctaagcaagg ctggaggtac tttttcgcca ctaatatcac
     6421 gaggtcatat gggcacggtc tactcgattg atgtcggtgc tcgggctcag ctctttcggc
     6481 ccaacatcga tgcttttcac tcgagaaaag atgcacagtg cttcttcatg atcttattct
     6541 ccaacaggca aatcacttgc tcagattgtc tttgggtcat caccagcaac gagcgcttga
     6601 acgaaagtct ttttacatga cttcttgttt ggtgctgcaa ctatcgacac aggagttcct
     6661 ctgctgctct gctgccatca accagtcgaa acaatggaat cgaccatccc agccaaaccc
     6721 gatttttcaa acaaagtctt cgccaaagac gagaggttct ggctcaacta ccttgagggc
     6781 aggcccacag cgccaaagtc cttcttcgac cgcatctacc gctaccacga agagcatcgt
     6841 ggccatttcg gcacggtcca cgacgtaggc gccggcaatg gcccctatgc gaaagaactg
     6901 cggctcaagt tctcgcacgt cattgtttcg gacattgctg ccgaaaacgt gacgctcgca
     6961 caggagcgtc tgggtaacga cgggttccaa taccgcgtca gccgcttgga agacgcggat
     7021 gacatcccgc ccggcagcgt ggacatggta tttgccacca acgtgttgca tttctgcgat
     7081 caggacgtgg ctatgagagc acttgccaga cagctacggc ccggcggcac tttcgcatgc
     7141 gcaagcttcg ggtcagccta ttttgcggac gagaaggtgc aggaaatcta tacccgtatc
     7201 ggccgagctg gggcccgcct gctcctcaag acgctggacg accccgagag gcttcttcgg
     7261 gccatggacc gcaccgacgg cacctacaat gttgcgccgc tggacgaaaa gctctttatg
     7321 ccgggcgcgc agcgtgtgga cctgaatatg cccgagaggg gtatgctgtc acctcttccc
     7381 ccggaaatgg aggtgacgga gcgggatgag tcgcacacga ggccgagcga tgtcctcatc
     7441 caggaggagg aagatgaatg gaaattttct atgaacattg gacagatcaa ggcgcacatc
     7501 gaatcgtttc cctttgggaa agacgtggca accgagctga gtccgctgtg gcgggagatg
     7561 gaaaatttgg tgcaggacag acggattgac ggacattggc cggccaagat tatcctggcg
     7621 acgagagctg acgcgagtgt ggagtagcgg aatctgggtc tcggagaatt tcattctacg
     7681 tcggcgtgtt aatctaccgg taatacatca tgcatgcatg gcggtgtcgt catcgggata
     7741 cggtcaattg agtctcgtcc aatatcaagc gccaccttct tgcaaagcct gccaacactg
     7801 gtgattgaga tcaatctcgg catgttccga agaccgagac atacctacct accctgtgca
     7861 atgacagtcc acacaataga ccgaatctgg ggcaaatctt tctccattcc cccccgccac
     7921 ggtttcacac gccttcttga gaaatgccgt gcaagatgcc gaaacgagaa aagattgaaa
     7981 agagacctga tttggcatgt ctatctgccc aatgcctgct tgtccaacgt tctacaaact
     8041 cctagacaga attctccaca tttccttcct ccacgaataa tcttgtgtag aaaaaaagat
     8101 cctcgcccca ggtttcccgg aaaatgcctg cccctgccga ggtccagcaa gcgacgctga
     8161 gcaagttcgt cgatgcgtgg aagaggtgga acgccgacga ctttattggc ctctggtctg
     8221 actcgttcac gttcaaggtc ctgccactta gcgatgggaa gccgacgagg ccacgggaca
     8281 aggttgcgcc gctgtatagg aatctcattg ggacgctcac ggactacaag gtacgtttct
     8341 cgtgagcatg ctcaatacat gtgaactgaa accggataaa acatgataca aaagtaaaga
     8401 tgaggctatt caaagcatgg agacgaagac tggggcatat caaaaaaagc gtgttcatct
     8461 gtcttcttcc atttgagacg gattaaggga gtttccatcc agctgatcca tttattgttg
     8521 ctcaacagct tgacgtcaaa cacattgttc acgacgcctc aaagggaaag gcctgcatct
     8581 acgccgtcgc gagcgccaac gccccctgtg gggactacaa gaatgagcag gccatattca
     8641 tcaccttcag cgaaagcggc gacaagatcg agagcatgga ggagatgaat gacaacgcgt
     8701 ttcggaagga gtgggatccc aagtaccacg cgtatcatgg gtatggacag cctcccacgg
     8761 cgaaggcggc ggcaggttct tagagtggag ggctctagat gagctttctg gtacatagat
     8821 gatagcttat ttggcatgag tgcttttggt gcagacgggg ttacgcgaaa ctggcaaacg
     8881 aggttacgag ttaccaacaa cttgagacgt gtgataagcc aagggttcta cctagatctc
     8941 acggagagac tagagtgcat gtcgggagca cgccatcaat gttcaaaata cgttcccaca
     9001 aagttatgtt ccgaagactg agacatacct acgctatcat ctatgtaggt aatttagaca
     9061 acagtccgaa cccgggcgaa tcgtttcccg ttgggacatt tcctccgcca cggtctcaca
     9121 cacccaccct cttgagaatg ccgtggaaga tgccgaacca aggagaagat tgaaaaataa
     9181 ccccgactga gcatgcctac ccgccgagtg cctgcttgtc aaatgcttca gaagatccta
     9241 gacagattct ccacatttcc ctcctcaaca aagaatctac aacaggttcc cggaaaatgc
     9301 ctgcccctgt cgagatccag caagcgacgc tgagcaagtt catcgatgcg tggaagaggt
     9361 ggaacgccga cgactttatt ggtctgtggt ctgactcgtt tacgtttcaa gtcctgccgt
     9421 tcagcgatgg gaagccgacc aggccacggg acatgattgc gccaatgtat aggaacttca
     9481 ttgagacgct cacaaactac aaggtacgtt ggcgttgatg tttctacttt ctagaaaacc
     9541 ttgagaagaa gagagaaaaa agacagatgc gagcatgtaa catgttcact acccttggaa
     9601 ttaaatcgag taaagcatga cccaaacgca aaaatgaggc tatttaaagc attgaggcat
     9661 tgcaagactg gggcgcattg aaaacgtgtc ctgtccatcc atctttccat ttgaggcaga
     9721 tgatagatga agggagttac ggctgacccg gttcgagccc aacgctcaac agcttgacgt
     9781 caaacacgtt gttcacgatg catcatgccg cgaacggcaa ggcctgcatc tacgccgtcg
     9841 cgagcgccaa cgctccttgc ggggattata ataatgaaca ggccatattc atcgctttca
     9901 gcgaaagcgg cgacaaaatt gagaggttgg aggaggtgaa tgacaacgcg tttcggaagg
     9961 agtgggatcc caagtgccat gcgtattggg gttacggaca gcctcccaag gcgaaggcgg
    10021 tggcaggttc ttagaatggg tccatgggat gcgaggatgc tgttctcgag atgggctttc
    10081 cacttctagt acacagatga tatcatcatg atagctgtat atgggtgttt tttttagaaa
    10141 tttagtgcag acgcggctac gcgacactag aaaacggaca acttgagagt gacggccgtc
    10201 aatgtttgaa aatagtaaat agtaaatacg tccccacaaa gtcagtgaga tggcaccacc
    10261 ctctgccgaa agtcacctcg tacgaggata catactcgtc atgttcacga catcatgtaa
    10321 gcgggccttt gaagtttggc tttatcattt atgtacgacg cccataacaa cccggcgagc
    10381 caccaatcgc tttgtcccgg agattcggtc aatggaaagc tgaaaactcg tagggtgtga
    10441 tttggacaca gttcaataca tactaataca ccgtactgag tacaactcat cagcccactt
    10501 ctcgttcgac aaatagccct tactaggtat tcagtgtctt tagcagaccg aacccacgga
    10561 cggattttga ctttttgcgt caaccccgct ctcttgactc tcgcagaact ctctccaaag
    10621 taaagggaac aaaatcatcg accagaataa gcggcaagta tggcatcaac tacgggaaca
    10681 gaagcaacgc catcgcgcat tagcctttct caagatcatc tcgggatcct tcacgatgtc
    10741 aaagtcaata ccgcgtccat cgagatagcc aacagcctcc tgcagaaaaa ccacgaagaa
    10801 tggcacatgt tcttccgcga ccgagctgga cacaaccaca tttcacactc cattctcacg
    10861 tgcctcgccc ttggcggctc tcccgaggac atccagcgag cgtacgatga cggcctagaa
    10921 atccaacgac ctatgccccc ccttgacgac gccctggtag cgcgtctggg cgacgacaac
    10981 gtcatgtacg agtccctagg ctccatctca cagtacagat cattcctggc ctacttccag
    11041 caccacatgg aagagcacgg atggaaagcc accgtcacaa agtacctctt ctcgcacacc
    11101 aagctctccg agaagatgct agcacgaatg tacgagggcg cataccaccc cgtgattcat
    11161 ctcggcctag gcttcgagtt ccagcagcca gccatcgtgg ccgaggcgct cgcccaagca
    11221 gccgcccacg acgacagtaa cctatacacc tacttcattg cgtgtgagga agaatccgaa
    11281 atcgcgtatc cgttgcagca ggcgaaaact cttctgcaga tcatggccga tgcgagcagc
    11341 agcaagacga tccgcaatgc gccgcactgg gaagactacg ggaataagat gcgcgatggt
    11401 gttcttggcc gtgcatgtag ggagacggcg aatgtggcct ccaagtttgt cattcggaag
    11461 acgccggagt ctttgcgccg tcgcacggcc gagatgattg acacgtgtgc gtatgtggct
    11521 gcctcgagtc agcgatctgg ccggaagcgc aagattgact tcttctacat gcacatggtt
    11581 accagctcgc tcttcttcag tgtcattggt gagcaggatt ggattccgct gaatgaccgg
    11641 atccgcatgg ttgagtggaa ggctcgactc gacgtggcat ggtacgttgt gtgtggctgt
    11701 gccgacattc agcagctggc tctcacggct tataatgacc cagttacgga tgggatggga
    11761 tgggaggaat tgtatgcggc ggtggtgaag gagcatgatg atgggcatgt ctccaagatg
    11821 attcgcgctt tgaagaatgg ccaggaagct gcgcggccgt ttgagaatgg gccgtacaga
    11881 aatgcgtttc cgcttcatgg cgatatgtgg ctcaaggcgg cgcgtatgac gctgggtacg
    11941 acgacggggt gtgatgaaga cacaaagttt gttatgttta ctggctttga tatcccgtgg
    12001 gagacgcgtc cggatttgca gtagtggtgg attacatcac gggtccggac tccggggtga
    12061 cgggaaagta gtggctgaag tttgggttct cgttcgtgta tcaactcacc gagatctaca
    12121 ttgcatttag gcttcttagt tttagttaat ttgatcatcc gaatggttgt gagcggcaaa
    12181 atgatctata gactatacgt attatgtata ccaaagtatc gcaacggtca ttgacacaga
    12241 tgagacgcgc atgcttctca ccattccgac aagtctcgcg cgaaacggac tgagaagtca
    12301 agtacgtgat accaacgcca tttccatttc aacgtcacgc tgagcttatc gacagtacgt
    12361 attgtgttac aaaaaataat cgccataaac agtagctaga ccttgttatt cttttatact
    12421 actctcattg acgagtctgt ggtggacgtg ggatcccatc gctcgcgagt cgctaccaag
    12481 gtgtcatgtc ctcacttttg tagtaagaca atgaaggcat cggattgaaa atacaaaata
    12541 agtgacagta ataggctata gcagtgagag tgtcttttat ctctcactcc gcaaagattt
    12601 tgtcgaggtc aaactcggcc caccgaatct cgggctcaat tcccgcaaac ttccaatcgc
    12661 catctacttt gcgaaaccac gtcgtagctc ccccgtgccc gtgtcccttg agcacaactt
    12721 ccttcatctg cgcatctgca tatttctgat gtgccacccg catctggtga cgacccgtga
    12781 cagaatcctc gctcgtctgg gtccaacgcg tcatccccac gaagtgctgc gttttgatca
    12841 agggatttcc gaggaaaccg gggctggaaa tcatgccgac gaactcgtct gctggcatgg
    12901 cctcccagaa ttggccgaac acggcgcggt agtcaatcta ccatgagagt cagacagcgg
    12961 tattgactct tgagaacgca ctcgcgagag ttgtgccgtg ttctttcgaa aaggatgccg
    13021 catgacggtc attaataaaa cttacttgca gcgtgggtgc gatgcatttg gagagacgat
    13081 tccagtcttt tagatcgtaa ctctcggccc attcaaagag ggctgcttgg catgctgtcg
    13141 catctggaac agacgatcgt tagcattttg gagcggcaaa tacgaacgag tggatttcag
    13201 ctcaccttcg tacgagggag ttttagacat ttcaaaggtt cgctcaaagg ttcagggtat
    13261 gcgattgttc ttttgaagtt ggtctaggct cgaaaagtgt aattgtgtca acagcttagc
    13321 ctcgcatttg agaggggaaa ccgaggggga tacctatttt ttgactccga ttcccgacag
    13381 tagacaaaaa cagacgtctt cgggcctcaa caacatataa ttgactccaa tcaaggggct
    13441 ctcggtcatt cgcttgtgga accaacttca acagaagtga ttcgaccgaa ctcataagcg
    13501 gccgacgggc ccgacgcaac cccccgggtg tagccactat aaagtccgct cctcccaaat
    13561 gagcaatgca agaaaagaaa atacacaaaa tacatacaac acagcaatcg taatacatat
    13621 caattcatac atatccagaa aatcttcagt catgtcggaa actcacattc cataccgcct
    13681 ggacggcaag atcgccctcg tgactgggtc aggccgcggc atcggcgccg cgatggccgt
    13741 tgaactcggc cgtctgggcg ccaaagtcgt cgtcaactac gtcaactcag tcgagtcggc
    13801 cgaaaaggtt gtagacgaga tcaagggcct aggctcagat gccgtagcca tccaggcgga
    13861 tgttcgacaa gtgtcgcaga tcgtagagtt gatggacaaa gcggtgaagc actttggagg
    13921 gctggatatc gtgtgcagca attcgggagt tgtgagcttt ggccatttcg gagatgttac
    13981 agaggtgcgt tgcaagtctt ggcttataat cgttgcctgc gcaattgagc tgtccgccct
    14041 cttttatcgg aagtccaatg tcttttgcaa ttgagaagag gaaaaagaac aggatcaaat
    14101 tttaagaaag gagaacatgc acttatcagg agacacctca ataggaagag tttgaccgcg
    14161 tcttctctct gaacactcgc ggccagtttt tcgtcgcgcg cgaggcatac cgccacctca
    14221 acaatggcgg tcgcatcatt ctcatgtcct ccaacacggc caaggatctc agcgtgccca
    14281 agcactcgct gtactcgggt tccaaggggg ccattgactc gtttgttcgc atcttctcca
    14341 aggatgctgg cgacaagaag attacggtca atgcagtggc gccggggggg acggtcacgg
    14401 acatgttcca cagttgctcg cagcattaca ttcctggcgg cgacaagtac actgccgagg
    14461 agcgccaagc ggtatgttga gacggtgttg caatttattc ctgtcttcga tgaacgtcgt
    14521 agaggaaagt cacgggctat gatggctgac actatggtag atggctgctc acgcatcgcc
    14581 cttgacgcgg aacggattcc ccctcgacat tgccaaggtt gtgtgcttcc tggccagcga
    14641 tgaggcggaa tgggttaatg ggaaagtgct cacgttggat ggaggagctg catgaatgat
    14701 gatgagcgta tcactatccc agtgttcact gttgctctgt atggcgtatg aaggacagct
    14761 ttgggccttt ggccatggga tatttgtaaa attgcacttc tgaagtgtaa gaggccacga
    14821 ttacttgcgg attctctcaa gccctgcagt ggatcatgat gtttcttcat cttgccatag
    14881 acttgcgatt gtaaagacgc ataaccgacc atagcaagct tgcaactgaa tctgtcccta
    14941 gatgatccaa gcattcagac catgatgtcc gagccagctg ctatgtacct aagggccttc
    15001 caagtgctgg gcccaccgtc acccacgtga gcggtgggac tgagatattc gtcaacgaac
    15061 gcaatgaggc attatttctg ttctgctgcc ttctgcaaca ttgtgcataa tctacacacc
    15121 gattgtttca gatacggtcc tctcagacgc aagagagacc acaaaaggcc ccaacaggac
    15181 cttcaacgat tacatctatc ggaggctata ccccaagatt accccaattc ccgacccgac
    15241 gaataattcc ccggacccga acgtgagcag accccactgc gcctgcctaa ataggaacga
    15301 tgggtacgta cctttacggc acgggcctag cgcacggctt agcgatccat cgaatcacaa
    15361 caagcgtcag caaacaccgt tgcacttgcc tgcgattggt ccgcatcaac cccaacccca
    15421 acttccaagg gatgaacgtt gaggaccgtc gggttattaa tctcgtgctc ggaatattgt
    15481 gtcttggcca cgccccgcag tggcaaccta tcaaagcttg ccgttcctcc cgatcggcga
    15541 gcttccggtc cggtttccgg tcggttagtc ttctccgaag gggtcccgct ttgtacattc
    15601 cttcgggtgg cgaacacgaa caagaagaaa ggagacaaaa tccggcaact cgggacccgg
    15661 gcagggccca gggggggttt acccatgtaa caacgctgta gcctgtgcgg catttattag
    15721 agcaagggag cacaatcttc ggaatgtgct taataaaagg ctctgatcca cgagcgccga
    15781 caaactttca tacacatagt ggataggtac aaggcgaatg tgggtcgccg actctgtacc
    15841 acacgtgaca cagtaccata cagggattac caaagcggca ccgccttccg ttcgtggccg
    15901 agaatccggc aaaaatcgtc gaagcgccag tgccggtgct ttccgccgtc ccagcgcctc
    15961 gatatagcgg ccaacacccc ccgcgagtgc taaaactcgc tgcgactgcg ctgcaacagt
    16021 gctgtgcggc gccgcgtgtc aggggttctc tgtccatcag acatcgggat tgcattaata
    16081 tcgatacagc agtgacaaga tcgtcaaaat cgtcatcttt cacgatacta tgctctatag
    16141 aaaggtaatt actgccgatg aatgccgtca tggtggcgtt ggtctcattg ttgattaatt
    16201 gattgattga attgaatggc gtcggcgcgt gggaagactt tgcatgcatg taggtaaaaa
    16261 tgtttgtcgg cacgtttttc ctgccgacaa aattcaggcc gacaaacatg caaagtaccc
    16321 actttcttcc tattgtaggc atctacgcgg cccctactag cgcggtacat cgaaagcatc
    16381 tcgaacggga tttaacgaac ttttcgactt aatccatgtc atttagtggg gcgagctaga
    16441 cgcttttgga caaaaacccc gctttgttac gagctttttc tctgtcggcg ctcgtggatc
    16501 agaccctaag attgacctga gattggggct tggctttgag atgagcctag ccggcagcat
    16561 ctgcaccacc agtgaccaca actgaaaatt ggtgagaccg gttctccttc cgggccgaaa
    16621 cacgctctct ctctcttaag tcagggattt gcatctcggc tcttggggtt tgcggcccga
    16681 agaagcaaat tgaccccctg agcccgattt cgacgtcgtg cgacacataa agtcggggcc
    16741 tcgtgaaatg aaccccctct ttgtgttacg tatctttctt ctgctgtttt ctgaaattct
    16801 cgtgtgaatt agtcccgttg attatgtatg aaatgttgtc tcaaagaaaa gcacaattat
    16861 gtacaggcat gcgtaatatc gcgcattctg atcagttgag ttcgaattcc tgtttgatgg
    16921 gaatacggcg acacgacaca tgttcttgca gaaagggcac cgcctaggaa gcaaagagtc
    16981 cgtcttcttc gctaccgact atcgattgaa ggattgatcg tctgttgtat ctattgacag
    17041 ccggtgttga gagctttttt ttgggcgttg ttgttgtgaa cacggaaggg caagggctcg
    17101 gaacgggagt actttttacc gatggggttg gcagtgacca atcagcgagt gcgacctttt
    17161 tcttgcggaa aaaaacatgc ggacacaaaa tcgcgtaact ctctgtctgt attttttttt
    17221 gtggggcaaa atgcaaaagg cgttatttca atatagtata gatgacatcc ccatcatcag
    17281 tggtgaacgc acgtatgtat atcttgcata aagctaggca gcattgaaaa aacgttacct
    17341 aatgctacgc gggacatgat gacgctgagg gtaaaagaaa gagccccccc ccccccccgt
    17401 tcttcgggct ttcgtgggcg ggcagaaatg gggatccgat gggttgtccc gacagaaagg
    17461 tgagcgttgc aaagttctcg ttgatgattg atatacatac atacggagta tgtacataca
    17521 taccggtacc ggcggtacgt acgtacgccc atggcggggc agcacgagaa aacaagagtg
    17581 ttggaacttg cagtccttgg ccctaattag tgcgcgtcat ttgtctcacc ttcccggctt
    17641 tcttccatat ttttctttcg tcgcttgatc gggggctgct cattatcgtg agatgtgcct
    17701 aggtacgtgt gcccactgat gatgaaagct ccatctcaac atcttttacg ataaaacata
    17761 tcgaaacata tcacaaacta atcacaaggt ctgagatctt cttctgcatc cccctctgat
    17821 ctcggcattg tacatactcc acaacatatt ccataatggc ctcatacgca gtgctgggcg
    17881 ccaccgggaa ttgcggctct gcgttgatcc agctcctgct gcaacgcccc gatgcctcta
    17941 tccacgcttt ttgtcggaac aagcccaaac tcataggcct tctacccgaa attgagaaga
    18001 gcgaacgcgt caccatctac cagggcagca tcaaggacac cgatctactc acggcctgcc
    18061 ttcgtggccg ccgcgccgtc ttcatggtcc tctccagcaa catcaacgag cctggatttc
    18121 gagtaggccg agacgccaac aaagcagtca tcgaggtgct tcggactctt cacagagaag
    18181 acagcgggtc tacaggtcct cctcccaaga tcatcttgct gtcttcggcg acactcgacg
    18241 ataccttgtc gcggaagacg ccctacctgc tccgacagat cttgcatatg tcggcatcgc
    18301 acatctacaa tgatctggca gagacggaaa agttgctgcg tgcggagcaa gagtggctga
    18361 cgaccgtgtt tgtgaaaccg ggggcgttgt cggtggacga gcagcgaggc catgcgttga
    18421 gcttcgtcga gtcagacaat cctgtctcgt acttggactt ggcggccgcg atgattgaag
    18481 cagcagatga tacgacggac aaatatgata tgaagaatat tggcgtggtc aacaccaatg
    18541 gcgcggcaag atttcccacg ggaacaccac tgtgcattgc cacggggtta ttgcgacact
    18601 ttgtgccgtc tctacatccg tatttgccgt aatacatcgc ggaacttgct tcatcgtgcg
    18661 aagtctcacc ttttggctca caaggaaagg gattcgaaag cgcccccacg caagaaaatg
    18721 acaggctttg catgggccga gaaggcaaag gttatacgga gcttacgacg gagcttacgg
    18781 aggatcctgc cctggcatgg aagctgtcta tcaagggtgg cgccatgaaa aaatgaggca
    18841 gcctactggc caatacttta gcgccaacgc ctcctttcat tcttgcagca atcattagta
    18901 tctttgttta aaaaagttca agaagaatct accaatcatg gcggtgtatt atcgtcatag
    18961 cgggatcatc caggtgcttg gtggctctag ttttattgat cacagatgat cccatgtatg
    19021 taggtaggta ggtggttatc tttctcgtcc attaaaggcc caccccttca ccttgcacgc
    19081 atgattattc cgtcgacgac tcgactattt gtctgattat ttgtcgcatt atcatttggc
    19141 gctcatcagg ttatatcggc gacatataat aggcgtctca tatatcttgt atacgctcgc
    19201 aggcgaatct gaaaatttga aatcagcatg gccaactcgt cagtgtacgc tgatgtcatt
    19261 gtcgtgggtg ccggcccggt cggcctcttt gtcgcatgcg aactggcact ccacgacgtg
    19321 tcagtcattg tgctggaacg agacgccgat tcagataacg tatggaaaaa aggacttctg
    19381 ggaggtcgcg gaatgtacaa gccggcgctc gaagccttct accgccgcgg tctcttggcc
    19441 gacctgctgt atgatgagaa gcgagtcacc tatctggaaa agacttccgg attccaatac
    19501 gctggccatt ttggtgggcg acttctgaac gccaatgcgg tggacttttc acgcttcaag
    19561 tatcatttgc cagggcctac atttcttccc gccaagacga ccattgcgga catcgaatgc
    19621 gagctctcca aacgggcaac agaatgtggg gtgcgtatcg tgagaggcgt ggagatctct
    19681 cgagttgaag atgaaggcga tgaggtaacg gtctgggccg acaatcagag tttcaagtcc
    19741 aactggcttg ttgcgtgcga cggtgggaaa agcacaattc gcaaggctgc aggatttcag
    19801 ttcacaggaa ctgactctga gcttacctgc tacatcgctg tatgcgatgt agataagcca
    19861 gagctactcg gaaagggcat gaagcctacc gacgctggaa tgtatatagt cagcgggcca
    19921 cgacacttgt atgtcatgga ctttgacacc accttcgacc gctctcagac cgtcaccaag
    19981 gaacatctcg agcgggtcct gcagcgggta tcgggaacga gtgtcaagat tgaagcactt
    20041 gagcttgtgt caacattcac cgatcggtgc aaacaaacga cccaatatcg caagggtcgc
    20101 atcttactcg cgggcgatag tgctcatatc cactctccac tgggcgccca aggcttgacg
    20161 accggaatag cagatgcttt caacctcggc tggaaactag catctacagt caaaggctat
    20221 gcatccgctg accttctcga cacataccaa cgcgaaaggc agccagaagg cgcatggacg
    20281 ttggattggt ctcgctcgca agtcgtcatc atgcgcccag accctgccgg aaaggccatt
    20341 tctcgcctag tcactgagta catggctacc gatgatggta ctaccttttt tgtcaacaag
    20401 atctggggaa tttctcgacg atatgacctt gtgggtgccc aagcgcaccc gctggtgggc
    20461 tgcagtgtgc ccgactttca attcgaggat ggatcgtatc ttggcagcaa gcttcatgaa
    20521 ggaaagttca tgaccgtcga cttcagtggc agtaaattat tggaggaagc cactgatctt
    20581 gttcaacctt gggtgggata cttgtcatgt tctgtgaaag atcgtcttgg catgaacgca
    20641 ctcctcttac gcccagacgg ggtcgtggcg tgggtggcgg aggatgaagt gaaggttgac
    20701 agctggaagg ctgcattatc acagtggata gttctacctg gagaggcttg aggggctgtc
    20761 tgactcaaga ttgtgtgcgt cgagtcagtc gaaacatcgt gacgaagata ttagaaccac
    20821 ctactctgca cgctgtcaat ggacgtctgg aaaagggggg tggggtacta gttgacgcac
    20881 ccgtggaggt atcatgaaac gtttgaatag aataagtaga agcaggtgtt taagccaatt
    20941 gatacgtccc atacgcgatg cgagcttaga attcgtgcgt gaaaacagtc tggtgatatg
    21001 atacacgttg cagaagatca agcatcaaaa cgctccgagg cccacaaagt gatgcattgt
    21061 gattggccaa gagcagcgga gcaaggcaag gccggtgcaa tcgcacgtga ccagatcgcg
    21121 ctctccttcc ttggcattca cccccccttc tcttcgcaag ccaaactcaa cttgcccctc
    21181 cggccatcag ctggtacttt accaccacgg cgactgtcat gccggagcat gagcgtagct
    21241 tatggaccag gaccaacttt cccgtactat ctcgaaccgt gtctagcatc tgcagcaagg
    21301 aactcaggtc catttccacc tcgttggaca tctgatacat gatcaatccg cgggcatgcg
    21361 ccaccgctgc atgcctcgct cggatgggct cgtcctgacc cggaagaact cgacccgaca
    21421 tgatgagcat gacgccgttg ctcatccgga gagcgggcag gtggacttgg agctcggtca
    21481 ggatctggct cggcacagat gatggtagat ggaggacata tacggcagca ttggtcaccg
    21541 attgtggcga acctggcaca cgattggcaa tcgaaatctg tcctggcttg atcggatctg
    21601 aagggtcgca caaaatcgat tcgcagctcg acgctccggc cggaagctga acgagaaagc
    21661 ggagttgcgg gaacaaacga gccagcggct tggcagccaa gaacgccccg acctgttggt
    21721 gcaaccatgc accgtgcata gcagttcgtc agttcgtcag ttcgtcagtt cttcagttcg
    21781 tcagtgctaa gtgctaagtg ctaagtgcgc ctgcaggtaa gactgaggtc cgcgaacaaa
    21841 cccgagaaga aaatgggggc gggccagtga gagtatgaga agacataaag caggttgagg
    21901 aacagggaga tggtgagggc agagcggcgt aaaatgcggg ggcaagtctg gtgcgacgtc
    21961 tcacctcgac aacttgtcct cctgctttgc ttatattgct ccaatgtaac ttggccattg
    22021 cgtcggcaag gacatgatcc tctggcagcc cgccggcatg gtgtagatat gcagcccact
    22081 gacgggagag ccttggactc tgctcttgag ccgcttcgaa cggcaccttg gtcgtcgtcg
    22141 ccaagctaaa ggcagtctcg ttattcgtat gagactctgt gaaccgctgc gtcgccgtcg
    22201 ccgacttgag tgccgcggga gccgcttgct cagctagaaa catggctgca tccaaatggg
    22261 aggggttagt cacgaagctc gccgagagag gcgtatgagc gacatagcct cgtcttggtt
    22321 cgatgaggaa gccacatctg gctgtgaggc ctatcatctg cgcgagctgc tgttctggga
    22381 cgtttgagag attggcaaca tcctggatcg ggacctcctg gctgagaggt atgcaagcca
    22441 ggatttggaa ctcgcccagc cattggatac ttccaagcat ctcacactga cacgtcattt
    22501 tcggcagtca gtcaagtcct ttctttcctt cgaagaaatg agaaaacaga caaagttcct
    22561 acccccaccc cccctttaca gggcatgcag ccgccggtcg caagaatttc gtcgagcaca
    22621 taagaaggac aaaaggccac agacctggat ggcaatattt tcaaggaact ccttggggcc
    22681 acggacgatg gcctcgattt cgctcaagct cgataagatg ttgcttctgg cttcacttcc
    22741 gtcgttctgg ctctcacatg ctgctgccag aaatggatgt tgacaatcaa tacttgaata
    22801 cgagctgacc aaagcgttga cctctgtcaa cagtctgttg gtaaggccat gcagctgttc
    22861 ggaagtagcg gcatccatta ttgttggtcg gtcgcttggc acacgatgat atgatgattt
    22921 cgaggtgagg agtggacgta gaatggacgg aagctttttg agtgctgcga gcttttccat
    22981 gataaggaga attcgaggct aggctgtttc ccatgttgag acaaacgtcg ggttctcccc
    23041 gcaaaaacca tctgcgaaat tctgcttctg aatttggcat tgccggattc atctgcactc
    23101 gcttcttgtc acagcacctt ccgcattatt tgatctacat ctagaactgc ggggcgaaag
    23161 gctcgtctct cccgtcacaa tctcgtaact ttactcatat gctgccgaca gggttccctc
    23221 gcgtgtcaca acagatgcgc aggcgcaggg gtcttcacga tcgggcatta ctggttggtc
    23281 cataaacatg catatgcatg caggcttctt cttcaacttg gcataagcgg taaaaagtac
    23341 cgtgttccaa aaatggcccg gtatcattgc gcgtggaggt aggtagtgcg ttgtccctat
    23401 ctgacttttc cgccacttct tcttttccgc cacatagtta tatcaagtcc ctttgtattg
    23461 gatgattagt cctccgctaa cgattctcaa gcatagtaat acgcaaatgg accttctcga
    23521 tttcccctgc atggtatttc tgcagctgca gaatagagta cgacgcagac ccgttcttca
    23581 gctcgagact ctcgatcgac gccgccattc gagaggttat tccaatcaga ccagatcgct
    23641 agataactga tagcgatgtt gggttttccg agatttgtac gacgcgaacc aggttggcag
    23701 cctcctaaca agcagttgaa ctaggtcaac ggcctcgact cacctagaac gtcttttacg
    23761 atgtatagag ctacggatat taaatcgccc gtcggtttta atggcgcatg cactcacatc
    23821 aacccaacgt gggacgtggc tcacgtggat ttagacgcgc cgagtgaaca agaaagggga
    23881 ccacttcgcc acacctcccc ccacctgctt ataaaaaagg aaagaaaaca gaagaagaaa
    23941 aatgagtaat cgaaaaatga ttgatagttg atcatgatat gattcatgcg gccatgagaa
    24001 ggcggcgaaa cgactgcggg gggattccaa gaagctcacc cactcctcat tacaactcga
    24061 gatggctgag taatactata ctgccatttg ctcgagggaa taagtcaagg cattcttcag
    24121 tgcagtctta cctctagctg aaacatgcat ggccggctgt ctcaatacgc ttttggtgtt
    24181 ttctttcctc ctgttgtgcg ttccgaactt gactcacatc tgactagccg tgttcacaat
    24241 ctcgaggtgt agcatgcaga tcggtcccga ttagagcctc agcatgcatg tccagcggct
    24301 accttattca gaaatgcaac accgcagtct ttacacgcag tagatatgag gattgaaatc
    24361 ctttttctcc cacgcatggc cgatattggc gaacaagaga gacctttccg caagctcctc
    24421 aatcacccga gcacttgtat aaggcgagtt cgacacattg gattacgcgt cacgccgcaa
    24481 cctccgtcct cgaagggaaa ccattcattg ccccctctcc ctttcccggg ttgtccgcct
    24541 tcggccccct ccctcgtgga ccctctctta ccctttattt caccgacatg gaccattcca
    24601 ttggcggcag aaattgccag agcggcggga caacggcgtc tgctccgcga agcacaggct
    24661 cggatgaatt cccatcgaag ctacgagaaa cctgccacgc atgttctctg tctaaagtcc
    24721 gatgctccaa ggagaagccg tcttgttccc ggtgtgcaaa acgaggagtc ccttgtgaat
    24781 acatcgtcac gaagcggcct ggacgcaagc gtgatcccac caaatcggcg ggtctcacaa
    24841 gcagccactg caagagtttt gatgctgcca cggctgcgcc gaataatacc aatgcgaatt
    24901 gtgcctggct cgaagacgtg ttgctcacgg atatgggcgg gagtggagga ggaagtaccg
    24961 gtcatgcgta tcttgactcg acacaaaccg acacaggctc acccatgttg tggcccttga
    25021 tggccaacga cggggcagat attgctggtg atatgtctga tttcctcatg cctctgatca
    25081 cgccgctgtc ttgtaccttt acggccagga cgccagactt ccttagtgcc gcagctgagt
    25141 tttcggcgcc aatctccccg cccaacaacc acgacgacaa aaataacaac cagtctatgc
    25201 aagatggctc caatgtgatg cagcttcttc tcccagacga cgtacatgga ggacatgctg
    25261 ccgagaatgc tgcccaggag gcgccgtctg tcgattttca ctccagttgc agttctagat
    25321 ccctgtccag tgtccctgag tcgttcctga gcagtaagat tgcgagcaat tcagacttcg
    25381 gctcagcctc aagctcatgc gaatgcctga tcaaagcact ggacatcatg gccaaggtct
    25441 cttcaaccga tctcgccgtc acgcccgaca caccgagcac gaggagaaat tccgtccaag
    25501 acgaagcagt tgtggcaggc cacgaccaaa caagtcctct gctccatgcc accttcatgg
    25561 cgaacaagca gaccattgag gcgctcagca acatgcttca tggttcctgc caagagaatg
    25621 tctatctcct cacatgcatg tccatgatcg tcttcaaggt tctccgaaga tacgagatgg
    25681 ctgcggggca gtccatctcc gctggggtac tcgacatgca cgaggcggcg cgcccgcgac
    25741 acggggacct ggatcgggat tctcttcgac gtgccgccgc ccagttggtg ctgggagagt
    25801 tgcacctggt gcagcagcta gtcagtcgct tatctcgccg gctgcagctg agcatggata
    25861 agacacccaa tgatggagca gactcggaac tcagcgatag caccctggcg acccgggtct
    25921 tcacgttgga cgaggacgat aaagcggata catcggcttt ttccgccgcc accttgtctc
    25981 agatggatca tgatctgcgc aagggtctcg cgaggctgtc atcaaatata attaacatgc
    26041 tgcgaagatt gtagcggttt tttctcattc tccttttttt ggatacacat gttttatttt
    26101 atagttcttg gtatgtacgg ggtagactga atagatatca tggcgcaatg tacttctccg
    26161 agcgatccat gtccgtaacc tccctcgggc atatgttcct cgggttacac tgtcccccca
    26221 agcctcaagg gccacgtcac tcccagccga agatttgctg gatcgtagcc ctgagtgtct
    26281 acacggcctt tccatccaca acaaactctt tgatccatcc aatcgtcatc ctgtatgggt
    26341 gtcaactctg ttatctgatg gaaaaagacg caaatgatgt tcactctttt cttttcttca
    26401 gggcaacgtc acgtgcttac atgcttctct ttgtgtccgc aaacatctca tggtcatgca
    26461 tcaggtgctt cttgtaccac ggatcctgct tcatgcgctt gtagtcctca atattgtcaa
    26521 agacgacttg gctgaagcag tcgaaatcgg cgagtcggca catttgcgga tcaaacagct
    26581 cggccatcag cgctcgggta gcattctgat tgtggatctg cgacgtgcgt aggtacaacg
    26641 gaggattaga aacggtgttg gacggcgccg cccgagcaga gtcacaggct gcagtggcga
    26701 gcattgatgt aggagaagta aaaggagaca gaagcggtca agtatgtatg cagctaattc
    26761 acaaaaaaat atttccccga ctggcccatc acctctgggt aaggaattga gatagagaac
    26821 gcagtaagta ggttaggtgc taaggtgata agtcatacct gtgtccagcg acgtatcccg
    26881 tacttcacca tgagatcttt cgtcatggga gcagacacat tcaccatgtg gtttcgatag
    26941 gcctcttcgg acatgccttc ctttcggtag ccacaaattg tgaggcacaa gtactccttg
    27001 ttgcgggggc tgtgcttggc catgcccatc ttcatgttga ggaagctggg catagcatgt
    27061 ctcgtgttcg ttttcgtgaa gaagagtgaa acagagaata aaactgctgc accaatggtg
    27121 cagataacca ggcttgacat tattgtgatt atttttatct gattcaacga attgatacac
    27181 actgagtctt tgagagaatg cggatccgtg tcttggatcg agtcttttgc gacaacttct
    27241 tcgctgcgct ttgcatcatt ttaatactaa ctagatgacc gcgtttcaaa cctcgtttag
    27301 cccattcaac aaaatggtgc agctaaatca gcctggacac gcgtctcggc tgccgacaac
    27361 tatcactatc atcatgtctt aatccagaat gatgggtaag gtcttaggtc cgtaggctgt
    27421 ctgcttgagg cctctttgga ttgactgttt tccccctatc gccgcctcat cgttgtacaa
    27481 tccgagccag ccccagactc aaatggggta ggtaggacgg tcttcgggtc gggcgacggg
    27541 catgagagac atacacgggt ggttgcatcg gcaagccggc acggtaaaga ccgagataag
    27601 ctttctgttc tacagttctg agcttagtga ctttctgtcg gaaggatgtg ccgcccttcc
    27661 cgtggctccg accgctgcgc cgtacaaggt acggtacata caagcaagtc tatgttgatg
    27721 tgccgctttg atactacttg ctactgaact tctgctcccc gccttcccgc aactggtgat
    27781 gacttgagac gtcagccgag gcgaccactt cttggccttt cttccacctt catcatatct
    27841 tttattgaca gctatcgtat ttacgtcgtc atacacgtct ccagcttcct ttccaagaca
    27901 tcaggacctt tacgagtggc gtccaacatc atgtgtgccg caatgctccg agggtttgcc
    27961 ccgactggtg tccatgttgt cgctctggca tcaggagtct tcctatctgg taagatttgc
    28021 ccaagatgat gtttcctacg attagacaca gtaacgcgtg tcgctaaccc ggtatcttgt
    28081 accaggcgcc atgttctccg tctcggcaat catgattcct acgctgctcg acacgaacaa
    28141 ggaaccagct ggtcttacca cgcaatgggc gcgtctatac cattatggtt ctgtgctgat
    28201 gccgtccatg tctgttgcga ttgcggccgt ctatggattt gcatcgacgc agtacagaca
    28261 gagcccacaa gggatgcgtt gtttggcagc cggcgcgttg accctggcga ttgcgcccta
    28321 cacttggctc gcaatgattc ccaccaacaa tgccttgttt gccatggcgg cctccgcccc
    28381 aggctttgct ggaatgcaag acgcaaatga aaaggcaaga gatcttgtga tgaagtgggt
    28441 ggtattgcat tcgattcgct caattctgcc gctcgcgggc gctattatgg gattcacggg
    28501 tatttcgagc ggacaggaag gtgtcgtcgg atccgcgaac tgatatgtca attgcctcga
    28561 gcgatgttgg tagatgatct gggacgtggt catgatcatc atctgtagga acgctgtgtg
    28621 gtgaatatat gactacggtg taatcaagat tcaagggaga gaagaaagag gtgaaagcgg
    28681 agcatcatac atgaagttgg aaaataatgt tgtgaacaat ttatcaacgt tgccataatt
    28741 gaatacatac atttgaaacc atgcaactcc aagatggatg attctactct acagagtacc
    28801 accgcctctt gcccgctcgc acctcaaacg ccaccttgaa atcacccgcg agcttccgca
    28861 gaacctcatc cgtgaaaggc gtcaaggcca aagtgcgtgt gctctcgtcc atagactctc
    28921 cataaatttc cgtaaccagg tcctcgacag tgatgctctt ctggcgcctc tggcgaactc
    28981 gtcctagtgc tagcaagatc tgcttctccc gtctccgttt gttggccagc tcagttcgga
    29041 tcttgcctgg caagtccgca atgacagctc cgtgggccga atagcccgtc aagcatcgct
    29101 ggtcaagcat gcgctgcata ctcgccatga aggtaccaag gtcttccaca gcgcttgtcc
    29161 cgtggcccag gatgttgtct ccggtgaaca tggcttgctc ttcttcgagg atgaagcaca
    29221 tgtggtcatc agagtggccc ggcacgtgga gagcgcggac tgtggcaccc tctacccgaa
    29281 agatctggcc atcgacgatg tcctgctggc cactctcggg ctcgttcttg tatatgtcgt
    29341 gttcaaggtg tgggtagatt cgtaggaggt ccggaactcc accggtgtga tcgccatgcc
    29401 agtgcgttaa gagaacatgg ctcagagata tattcaggga gctcaatgtg gactcgagca
    29461 gctcagccca ttcaatctcg ccgccagagg tgtccacgat gaggcggtgt ttgccagtgc
    29521 cgacaatgta tgtattggtg ccctggtacg tgaactatcg acgtggtcag aactcagaag
    29581 gacaaaagac tggcggcaag tgagaagctc tacgcccttg ggtaatgcca atttcgtata
    29641 cacgacacat accttgcctg gattttggcc gaggacccgg agaactcgtg gcgtgatctg
    29701 ctcaacgtct ggcagctccg ggaggttgtc ggtctggctt ttgagatagt cttcaaaggc
    29761 gcagatgttg agagagctat ttatttgcct atatccgccc ttgtcacccg ccatggtcgc
    29821 gccattacga tctatctctg gcaccatggt catttactgt ccaagacaat acaagttaaa
    29881 cacttgttgg atgtaaccgc tagagacaga aaacggtcga aaaaagaacc agtcgaaaaa
    29941 agaaccagtc gaaaaaagta tcagtcgaaa agagaaccag tcgaaaagaa ttcagacgaa
    30001 aataagtcct gcggaaagag aacctgtcgg aaagaagacg agacgaaaat gaaaccgctg
    30061 caaaataaag tcatcgagtc atagaccccg tcacgacttc ggttgagcag aaagtcctaa
    30121 gctgcactac cctcccaact cagaagcaaa caagcaagcc cctgtcccca gtaagtcaca
    30181 cagagcttct tggcatccga acttgttcac tccagccgca gaagacgggg caacagtctc
    30241 ccccacaatc tcaaggaggt ggctcggatc tttggactcc gtatcgggaa aggcagtaag
    30301 tgtctcgggg gtccgaagcg cccataacat tacaggtggt gtcacgttca cacagcgatc
    30361 aggtaggacg ttggttcgga atcggtccag ccctccatga ttcgctctcg gtgttgcctg
    30421 gtagatctct gtaagcccga caacggtgac tggccgattg tctttggggg ccgcccaccc
    30481 cctccccaag ggccaaaagg cattcccagc gggcgtcatg caacacagca tcagcttgct
    30541 gatgtacagc ggaacccgtc ggaggaaaaa aggagcacga ttggtgtgcg agaccacaga
    30601 tcttgcgcca tccctatcgg catctagatc atgcgaatag ataatttctt tcgcttgcgg
    30661 gcttataacg taaaacttgg tattgcacga taccttggcc gatcccttcc cattcaacat
    30721 cccccgatca agaggaacgg ataagccaag tgagggatcg aaaagtaagc aaggacgacg
    30781 agaaagaaag aaaacagatc agagaaaaga gaactccctg gaattccgtt gcattgaaga
    30841 agctcggttc ttcctaccac ggcctccttc aagatatgct ccatcgccgg ccatatccgt
    30901 aacgacgaca acgcctctac atccgccttc ccagtgttga actgaaagga ggactgtata
    30961 tcccaccatg gcgatctata ccccgaacaa gagctctgac gccaacagcg aatccagcag
    31021 cctgagagta atctttttcg gcaatgaact cccaaatgat gacttgcaga ctcatttccg
    31081 tcgtctccac actcgtagca aggacaaaaa tcatcccctg ctggctcgct tcatcgacga
    31141 ggctacgctg gttctgaaag aagagatctc tgccctgagc actgacctcg gtcgcttgat
    31201 tccgacgttt gagacggtgc tgcaatggtc ggaggatgcg aatgctagtc tccgagaggg
    31261 gttactgtgt ggtgcaattg acggcgtttt gcttgtcgtg ctgcaactgg cttcctacat
    31321 ctggtactgt tcaaatttcc tttcgctttt cttttttttc tgttttggct tcgtcctgtc
    31381 gcttttctcc tccttcatca atgtagttcc tgtgtccccc ttttggtcac ctactaatca
    31441 cgtccacagc taccatgaaa tcctcacgta cgataaagaa gagtgcgtac acatagctct
    31501 taccggcttg ggcattggct tgctctcgtc gacggccgtg tcccttgcgc caaccccgtc
    31561 acacctgcca ctggcgggag cagatgtcgt tcgactcgct ttccgtctag gcattcacgt
    31621 gttgggcgtg tcagagctgc ttgaagcgcg agacgtatca ggaaagcccg cttcctgggc
    31681 ttatcttgtg caaattgcag attcagacgc cgctcaggcc gaacttgacc tcctgtatgg
    31741 caacgccgag tcgtcagcca actcgaacaa gataatcatc agcgccgtga gccagacgtc
    31801 cattgtcgcc agtgggccac cttcgcggct caagctcctg ttcaacaaat ccccgctgtt
    31861 ccgtaacgcg cggtcgacgg ccttgcctgt gtttggcggg ttgtgccacg cggcgcatat
    31921 ctacggtgaa aatgatgcac ggagcatcgt agaatgtgcc tcgctcaaca ccgtcacgga
    31981 gaactgcacg cctctgttgc ctatttactc aaccagcacg gggaatccat atctggccaa
    32041 caatgcgacc gagacctttg aatgtgtcat ttccgagctg ctgaggaagc agatttgctg
    32101 ggataatgtc atcaacggca ttcgtgagcg cataaattac tcgggtgcat cggccgcggc
    32161 agttgaccat tttggcaatt cagcctcgct tcatgatctc gaagtggccc tgaaaagcgt
    32221 ccttcatgag tctcaggtta ctctcaccaa catcctgacc atgagctgcg tcccacctcc
    32281 aaaggaaatc tccccgcgca gtactggtct ttcgaagctc gccatcgttg gcatggcgtg
    32341 ccgccttcct ggaggtgcca cagacacgga gaagttctgg gacatcctcg tcaagggtct
    32401 ggatgtgtcc cgcaaggttc cggcagaccg cttcgatatt gagacgcact atgatcccac
    32461 gggcaagcag atgaacaaga gcatgacgca gtacggatgc ttcattgacg agcctggctt
    32521 gtttgatgcg ccctttttca acatgtcgcc tcgtgaagcg cagacgacgg atccgcagat
    32581 gcgcttggcg cttgtcactg cgtatgaggc cctggagcag gctggctatg tcgggaaccg
    32641 caccaattcc acgaagctgg agcgcatcgg aacgtactat ggccaagctg cggacgatta
    32701 tcgtgaggtg aatcagggac aggaagtcag cacgtactac attccgggcg gttgtcgagc
    32761 ctttggtccc ggtcggatca attacttttt caagtttgcc ggtcccagct atagcattga
    32821 tacggcttgt tcgtctggac ttgccgcgat agaggtatgt gatggcttac acccaactat
    32881 tttgcctttt ttgttttcct gattggctgc tgtatgtttc gagccaaagc actgacgcaa
    32941 ctctgctaca ggtcgcctgc caaggtcttt ggaacggcgt catcgacaca gcagtagccg
    33001 gcggtgtcaa tgtactcacg aatcccgacg gatttgccgg cctctgcaac ggacatttcc
    33061 tgacaaaagg acacaacgca tgcaaaacat gggattcgac tgcggatggc tactgtcgcg
    33121 cagacggcat cggctccttg gtcatcaaga ggctcgagga cgccgaggca gacaacgaca
    33181 atattctggg catcatcctc ggagctggca caaatcactc ggcggaagca gtgtccatca
    33241 cgcaccccca cgccgggcac caggcatact tgtcccgcca agtcctccgt caggcaggcg
    33301 tcgatccctt ggacgtatcc tacgtggaac tgcatggcac cggcacccag gccggcgact
    33361 acgaggagat gcaaggcatc ttggacgtgt acgctccatt gactaaacgt cgcagcgcag
    33421 acaatccact tcacatcggt gccgtcaaag ccaatctggg ccatggagaa tccgtcgcgg
    33481 gcacgacagc cttgatgaag gttctgctca tgttccggga gcaagctatt ccgcctcaca
    33541 tcggcataaa gggggagatc aatccaaaga tccccaagga tctggcgaag cgcaatctac
    33601 acattccaat gaacttggag agttggcgcc gcagatcgga caagaagcgc cttgctgtcg
    33661 tgaataattt cggtgctgcc ggtggcaaca cgaccatggt gctggaggag gccccgatac
    33721 gctgcatcga ggaaatggac ccgcgacaga cgcacgtcat atccgtctcg gccaagacga
    33781 agaattcgct ggttggcaat atcgagcgac tcattgcgta cctcgatagt aatcccgaca
    33841 cttcgctggc ggacttgtcg tacacgacca tggcgaggcg ctaccagcac agctggcgcg
    33901 tggcgatggc gccgtccacg atgaaggatt tgaagaagca actgtctgcg tatctggaaa
    33961 agattgatct cgtgaagcca gctgggaagt ctggcccacc caccgtcgct ttcaccttta
    34021 ctggtcaagg ggcctctcac aagtccatga acctggcgct atatcatgac gtaccgtcgt
    34081 ttcgcgacta tatccagaga ctggatgcta tcgctcaggg tcaaggcttc ccctcgttta
    34141 ttcccgcgat cgatggctct catccccaag atcaccaaca ttccgccgtc gtcactcagc
    34201 tcgcactggt ctgctcggag atggccatgg cgcaatactg gttttctctc ggcatcaagc
    34261 ctgacgtcgt tatcggacac agcctgggcg agtacgctgc catgcatgtc gctggtgtta
    34321 tctctgcgag cgataccatc ttcatggtcg gtcgacgggc tcagctcctg caagaaaagt
    34381 gcaagttggg cagccactcc atggtagctg tgcgggcatc tctggaagag atcaaacaaa
    34441 acacatcgtc gactgattca gacgccgagt tcactattgc ttgcatcaac ggacctacag
    34501 atactgtgct gagcggcacc aagaatgcca ttgacgccgt gtcgaaaaca ctcgagcagg
    34561 cgggcttccg atgcactaag ctcgatgtcg cttttgcgtt ccactcggac cagacggacc
    34621 caatcttgga cgagtttgaa gatattgtca aggcaagcgt tagctttcaa gagcccaaga
    34681 tgcccgtcat ttctcccctg cttggtaaag tcgtcttcga cggcaagacc ctcaacgcga
    34741 actacgtccg tcgggccacg agagagacgg ttgacttcat ctcggcgctg cacaacgcgc
    34801 agaagatgtc gaccattagc gaagacaccg tctggatcga agtcggcccg cacgccgtct
    34861 gcaccaacat gatcaagaag atcttgccgg cgacgaagct ggcgctgcca tctatgcgtc
    34921 gcgacgcgga caactggaag acagtttcgg acagtctggc tgcactgcac agttcgggcg
    34981 tcgagatctt ctggaatgag tttcatcgcc cctttgagag gcgtctgcgc ttgctcgacc
    35041 tcccgacgta ttcgtggaac aaccaaacct actggttgca gtaccaggga gactggtgtt
    35101 tgaccaaggg caacggcttc tatgggaccc tgggccaagg cagcggaagt gctgcgtcgt
    35161 cttcttctcc ttctttgtta gcctcctcgg tgagcaattt acacacgtcg acggtccagt
    35221 gcatcatcga ggagacaatc gacggcacaa acgggacggt ggtcatgcaa tccgatctca
    35281 tgcagccgga tctatacacc gcggccgaag gacatcgtat gaatgattgt gccgtggtaa
    35341 catcggtaag ttatccaacc gttttcttgt ttcaattcct ttttctcgcc ggggaaagtg
    35401 ggatgcattg ctgactgctt cgctacatgt agtcgatcca cgccgatatt gcctttactc
    35461 tcgcggagta tatgctacca aagctgctgc ccgcatccaa gaaattgaaa gccatcatcc
    35521 aagacctcgt ggtcaccaag gggctggtgg cgaatcatga tagaaactcg cctcaactat
    35581 tccgcgtcac cgccacaacc acagatattc tgcaccacgg acttgatttg acgtggcaga
    35641 atgttgacaa tgacggcaca gtccacgagc cgtttgcgac ggccaagatc acatttggtg
    35701 accctgagca atggctttcg tcgtggagcc ccatggtcca cctcgttcaa agccgagtcg
    35761 aggccttgga ggcgttggtc gccgacggca cggcaaatcg tttctcgcgc gcaatggcgt
    35821 atggcctctt tgccaagaat ctggtcgact actcagaaaa ataccgcggc atgcaatcgg
    35881 tcatcatgca cggcctggag ggatttgcca acgtgcgcct cacagacaag gagagtggca
    35941 actggaccgt gccgccgcac tttatagaca gtgtagcaca cttggctggt ttcatcatga
    36001 actgctcaga tgcgatcaac accgtcgaca attactgcgt gacgcccggc tggaaagcga
    36061 tgcagtttgc gaagcccctc accccggggg cgcggtacca gtcgtatgtg aagatgattc
    36121 ctcaggctga taactcaggc acatacctag gcgacgtgta cataatgcag gacggagaca
    36181 taattgggaa agtttggggg attgagttcc gccgctaccc acgcttgttg ctcagccgct
    36241 tcttttcagc accaggcaag tcctcaacga cgacgacgac caaggcaagc gtctctgctc
    36301 cggtcaaatc gaaacctgta gagacgaagc tttctgcagc gagcaagccc cccacggtag
    36361 cgcaaacggg aatcccaccg gagcagaaac ccgcgcccga agtccagccc gtgacaacca
    36421 attctccagc aacagcagca gcagcacccg cgtcgactca agcagcagat acagacactg
    36481 tctccgcaaa agcactccgc ctcattgcca acgaagccgc cctagatctg tcccagctcg
    36541 aagacgatgc cggctttgcg gagctcggca tagacagcct catgtcgctt gtgattgctg
    36601 agaagttcaa aatcgagctt gatgtcaagg tcggcggcag cttgttcttg gactacccga
    36661 cgattggaga tttgagaaag tggctcgagg aatattatag ctga
//
