BGC0001886 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001886 (Claviceps purpurea 20.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	36,704	neosartorin	Polyketide	47%

BGC0001886 - Region 1 - T1PKS

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Location: 1 - 36,704 nt. (total: 36,704 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 36,705
Label		BGC0001886

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001886.1	0.58	Polyketide	secalonic acids	Claviceps purpurea 20.1
BGC0000013.1	0.27	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001858.1	0.24	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.23	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001284.1	0.23	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001257.1	0.23	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001258.1	0.23	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001265.1	0.23	Polyketide	melanin	Bipolaris oryzae
BGC0000107.1	0.23	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001909.1	0.23	Polyketide	strobilurin	Strobilurus tenacellus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001886.1	0.87	Polyketide	secalonic acids	Claviceps purpurea 20.1
BGC0000013.1	0.60	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001858.1	0.58	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.57	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001284.1	0.56	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001257.1	0.56	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001258.1	0.56	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001265.1	0.56	Polyketide	melanin	Bipolaris oryzae
BGC0000107.1	0.56	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001909.1	0.56	Polyketide	strobilurin	Strobilurus tenacellus

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 10967 - 36704:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

CPUR_05437

PKS_AT (942..1245): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; inactive: 62.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 94.1
inactive: 65.6
Methoxymalonyl-CoA: 47.3
Methylmalonyl-CoA: 46.6
Propionyl-CoA: 29.4
Isobutyryl-CoA: 24.2
Benzoyl-CoA: 16.9
2-Methylbutyryl-CoA: 16.3
CHC-CoA: 13.4
Ethylmalonyl-CoA: 12.6
Acetyl-CoA: 7.6
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0