BGC0001895 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001895 (Streptomyces sp. CB09001)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	18,350	huanglongmycin A/huanglongmycin B/huanglongmycin C	PKS	100%

BGC0001895 - Region 1 - T2PKS

Download region GenBank file

Download region SVG

Location: 1 - 18,350 nt. (total: 18,350 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 18,351
Label		BGC0001895

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001895	1.00	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0000231	0.57	Polyketide	griseusin A, griseusin B	Streptomyces griseus
BGC0000272	0.42	Polyketide	spore pigment	Streptomyces collinus
BGC0000234	0.41	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001723	0.35	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000866	0.34	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0002514	0.32	Polyketide	julichrome Q6.6	Streptomyces sampsonii
BGC0002000	0.32	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0002404	0.32	Other	falcarindiol	Solanum lycopersicum
BGC0000196	0.27	Polyketide	AQ-256, AQ-270a, AQ-284a	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001895	1.00	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0000231	0.82	Polyketide	griseusin A, griseusin B	Streptomyces griseus
BGC0000272	0.74	Polyketide	spore pigment	Streptomyces collinus
BGC0000234	0.73	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001723	0.68	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000866	0.68	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0002514	0.65	Polyketide	julichrome Q6.6	Streptomyces sampsonii
BGC0002000	0.65	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0002404	0.65	Other	falcarindiol	Solanum lycopersicum
BGC0000196	0.61	Polyketide	AQ-256, AQ-270a, AQ-284a	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters from MIBiG 4.0

NRPS/PKS substrates

Type II PKS

NRPS/PKS substrate predictions

C4J65_11165

AMP-binding (43..441): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: IVMYAGGHLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

Type II PKS gene cluster prediction details

Cluster section:: 0 to 18350
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Malonyl elongations:: 8|9 (Score: 674.1; E-value: 1.4e-205)
Product molecular weight(s):: acetyl-CoA_8: 349 Da
acetyl-CoA_9: 391 Da

C4J65_11100: CYC C7-C12 (Score: 426.2; E-value: 1.4e-130)
C4J65_11105: KR C9 (Score: 461.2; E-value: 2.1e-141)
C4J65_11110: ACP (Score: 123.9; E-value: 4.5e-39)
C4J65_11115: CLF 8|9 (Score: 674.1; E-value: 1.4e-205)
C4J65_11120: KS (Score: 768.2; E-value: 4.5e-234)
C4J65_11135: CYC C5-C14 (Score: 424.7; E-value: 3.9e-130)