LOCUS       BGC0001895             18350 bp    DNA     linear   BCT 10-AUG-2018
DEFINITION  Streptomyces sp. CB09001 chromosome, complete genome.
ACCESSION   BGC0001895
VERSION     BGC0001895
KEYWORDS    .
SOURCE      Streptomyces sp. CB09001
  ORGANISM  Streptomyces sp. CB09001
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 05:18:07
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18350
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[3517:5964]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 674.1; E-value:
                     1.4e-205)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 349.356"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 391.392"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      3518..5964
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 674.1; E-value:
                     1.4e-205)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 349.356"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 391.392"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     cand_cluster    1..18350
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..18350
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001895"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..18350
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(426..1361)
                     /locus_tag="C4J65_11095"
     CDS             complement(426..1361)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610263.1"
                     /locus_tag="C4J65_11095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="AXL88811.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.8e-12, bitscore:
                     38.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.5e-07, bitscore: 20.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKAPPKAPPTAPPTAPPTAPAAVSAKVGRITLQAGGITVSALLA
                     RPLYAPPRATVVALHGAGMSAAYFHGQTRPETSLLTLAADLGFAAVAVDRPGYGLSSAE
                     LPRGQTAAEQAATLTAALGDLADRYDTGAGLFLLAHSFGGKPALRMAAEGTLPALLGVD
                     VSGCGDAYTAPPTEPGTRDGGWRRSWGPLRLYPPGTFRSGAAVVARVPPGELADAARWP
                     AEFGRLAGRIRVPVRFTFAEYETWWRHDPPALDRLRSRLSAAPRVVIEHQPDAGHNISL
                     GWAARAYHLKALGFLEESMRHHGVGRESRT"
     gene            complement(1358..2314)
                     /locus_tag="C4J65_11100"
     CDS             complement(1358..2314)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (8-146). E-value:
                     3.2e-12. Score: 38.9. Matches aSDomain:
                     nrpspksdomains_C4J65_11100_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (155-277). E-value:
                     1.3e-08. Score: 27.1. Matches aSDomain:
                     nrpspksdomains_C4J65_11100_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 400.7; E-value:
                     7.3e-122)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 426.2; E-value: 1.4e-130)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640239.1"
                     /locus_tag="C4J65_11100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclase"
                     /protein_id="AXL88812.1"
                     /transl_table=11
                     /translation="MPSEPHESAHEIEIEAEAEAVYRMLAHAEKWPQLFPPTIHADHVE
                     RGEREERIRIWATAGDTVKNWTSHRSLDPERLRIRFRQEVSTPPVAQMGGTWQIDALPA
                     GRSLVRLLHDYRAVDAESLPWLDDVVDRNSRSELASLKAVAESGTAVAELTCSFEDSVR
                     IRGDVGVVYDFVNRADLWTERLPHVLRVRLEEPEPGVQTLEMDTMAKDGTSHTTKSHRV
                     GLAPHRIAYKQITLPALISLHTGHWTFGPADERGDVTASSQHTFTVRTDAIEKVLGSDA
                     TVQDAVDHVRTALSTNSLATLALAKAHAEGLAVDSRS"
     aSDomain        complement(1484..1849)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C4J65_11100_Polyketide_cyc2.2"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="1.30E-08"
                     /label="C4J65_11100_Polyketide_cyc2.2"
                     /locus_tag="C4J65_11100"
                     /protein_end="277"
                     /protein_start="155"
                     /score="27.1"
                     /tool="antismash"
                     /translation="CSFEDSVRIRGDVGVVYDFVNRADLWTERLPHVLRVRLEEPEPGV
                     QTLEMDTMAKDGTSHTTKSHRVGLAPHRIAYKQITLPALISLHTGHWTFGPADERGDVT
                     ASSQHTFTVRTDAIEKVL"
     aSModule        1484..2290
                     /domains="nrpspksdomains_C4J65_11100_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_C4J65_11100_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="C4J65_11100"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(1877..2290)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C4J65_11100_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="3.20E-12"
                     /label="C4J65_11100_Polyketide_cyc2.1"
                     /locus_tag="C4J65_11100"
                     /protein_end="146"
                     /protein_start="8"
                     /score="38.9"
                     /tool="antismash"
                     /translation="AHEIEIEAEAEAVYRMLAHAEKWPQLFPPTIHADHVERGEREERI
                     RIWATAGDTVKNWTSHRSLDPERLRIRFRQEVSTPPVAQMGGTWQIDALPAGRSLVRLL
                     HDYRAVDAESLPWLDDVVDRNSRSELASLKAVAE"
     gene            complement(2355..3143)
                     /locus_tag="C4J65_11105"
     CDS             complement(2355..3143)
                     /NRPS_PKS="Domain: PKS_KR (8-168). E-value: 1.1e-12. Score:
                     40.1. Matches aSDomain:
                     nrpspksdomains_C4J65_11105_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     259.4; E-value: 5.6e-79)"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 461.2; E-value: 2.1e-141)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103042.1"
                     /locus_tag="C4J65_11105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketoacyl reductase"
                     /protein_id="AXL88813.1"
                     /sec_met_domain="adh_short (E-value: 3e-38, bitscore:
                     122.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQHEQQRVVLVTGATSGIGLAVARLLAGRGHRVFIGSRTEDKVL
                     ATVKQLQEEQFDVDGVVLDVRSADSVHGYVRAAVDQFGTVDVLVNNAGISGGGVTADVP
                     DEVWDDVVDTNLNSVFRLTREVLTAGGLRHKDWGRIVNIASTAGKQGVVLGAPYSASKH
                     GVVGFTKALGNELAPTGITVNAVCPGYVETPMAERVRHNYSRLSGASEAAILEKFQAKI
                     PLGRYSTPEEVAGLVGYLVSDTAASITSQALNVCGGLGNF"
     aSDomain        complement(2640..3119)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C4J65_11105_PKS_KR.1"
                     /evalue="1.10E-12"
                     /label="C4J65_11105_PKS_KR.1"
                     /locus_tag="C4J65_11105"
                     /protein_end="168"
                     /protein_start="8"
                     /score="40.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLVTGATSGIGLAVARLLAGRGHRVFIGSRTEDKVLATVKQLQE
                     EQFDVDGVVLDVRSADSVHGYVRAAVDQFGTVDVLVNNAGISGGGVTADVPDEVWDDVV
                     DTNLNSVFRLTREVLTAGGLRHKDWGRIVNIASTAGKQGVVLGAPYSASKHGVVGF"
     CDS_motif       complement(3045..3119)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C4J65_11105_0001"
                     /evalue="8.10E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="C4J65_11105"
                     /protein_end="33"
                     /protein_start="8"
                     /score="21.7"
                     /tool="antismash"
                     /translation="VVLVTGATSGIGLAVARLLAGRGHR"
     gene            complement(3177..3443)
                     /locus_tag="C4J65_11110"
     CDS             complement(3177..3443)
                     /NRPS_PKS="Domain: ACP (14-82). E-value: 2.5e-16. Score:
                     51.6. Matches aSDomain: nrpspksdomains_C4J65_11110_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 110.5; E-value:
                     5.2e-34)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 123.9; E-value: 4.5e-39)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640237.1"
                     /locus_tag="C4J65_11110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="actinorhodin polyketide synthase"
                     /protein_id="AXL88814.1"
                     /sec_met_domain="PP-binding (E-value: 6.2e-13, bitscore:
                     39.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHGVFTIDDLKRILLEGSGAPEGIDLDGSILDTEFSDLGYDSLA
                     LLETASRIEREYGIELDESVVGDATTPAALLDAVTAHLVAPAA"
     aSDomain        complement(3198..3401)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C4J65_11110_ACP.1"
                     /evalue="2.50E-16"
                     /label="C4J65_11110_ACP.1"
                     /locus_tag="C4J65_11110"
                     /protein_end="82"
                     /protein_start="14"
                     /score="51.6"
                     /tool="antismash"
                     /translation="LLEGSGAPEGIDLDGSILDTEFSDLGYDSLALLETASRIEREYGI
                     ELDESVVGDATTPAALLDAVTAH"
     gene            complement(3518..4711)
                     /locus_tag="C4J65_11115"
     CDS             complement(3518..4711)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (66-395). E-value:
                     9.6e-31. Score: 98.9. Matches aSDomain:
                     nrpspksdomains_C4J65_11115_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 639.2; E-value:
                     3.6e-194)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 674.1; E-value: 1.4e-205)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544761.1"
                     /locus_tag="C4J65_11115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketosynthase chain-length factor"
                     /protein_id="AXL88815.1"
                     /sec_met_domain="t2clf (E-value: 6e-201, bitscore: 657.7,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVSAVVTGLGVTAPNGLGARDFWAATLAGKSGIGRLTHFDVSGY
                     PAKLAGEIAGFEAAEHLPSRLLPQTDRGTRLSLVAADWALGDAGVNPAELAEFDMGVIT
                     ASSAGGFEFSQNELKNLWSRGGQYVSAYQSFAWFYAVNTGQISIRNGMKGPSGVVVTDQ
                     AGGLDAVAQARRHIRKGTSLVVAGAVDALLCSWGWVGLHTSGRLSTEEEPTHAYLPFDD
                     RAAGHVAGEGGALLVMESAESARARGARVYGEIAGYAATFDGRESGLRKALELALDDAR
                     VHPSDVDVVFADAAADPELDRVEAEALVEVFGPNGVPVTAPKTMTGRLYAGAASLDLAA
                     AFLALADGVIPPTAHIEPASRYGLDLVTSQPRAAELRTALVVARGHEGFNSAMVVRS"
     aSDomain        complement(3527..4513)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C4J65_11115_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="9.60E-31"
                     /label="C4J65_11115_PKS_KS.1"
                     /locus_tag="C4J65_11115"
                     /protein_end="395"
                     /protein_start="66"
                     /score="98.9"
                     /tool="antismash"
                     /translation="LPQTDRGTRLSLVAADWALGDAGVNPAELAEFDMGVITASSAGGF
                     EFSQNELKNLWSRGGQYVSAYQSFAWFYAVNTGQISIRNGMKGPSGVVVTDQAGGLDAV
                     AQARRHIRKGTSLVVAGAVDALLCSWGWVGLHTSGRLSTEEEPTHAYLPFDDRAAGHVA
                     GEGGALLVMESAESARARGARVYGEIAGYAATFDGRESGLRKALELALDDARVHPSDVD
                     VVFADAAADPELDRVEAEALVEVFGPNGVPVTAPKTMTGRLYAGAASLDLAAAFLALAD
                     GVIPPTAHIEPASRYGLDLVTSQPRAAELRTALVVARGHEGFNSAMVV"
     gene            complement(4708..5964)
                     /locus_tag="C4J65_11120"
     CDS             complement(4708..5964)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (2-391). E-value:
                     4.4e-53. Score: 172.5. Matches aSDomain:
                     nrpspksdomains_C4J65_11120_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 488.2; E-value:
                     3.5e-148)"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     768.2; E-value: 4.5e-234)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640235.1"
                     /locus_tag="C4J65_11120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ACP synthase"
                     /protein_id="AXL88816.1"
                     /sec_met_domain="t2ks (E-value: 4.8e-244, bitscore: 800.2,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVITGLDVLAPGGVGVKNFWSLLSEGRTATRRITFFDPGQFRSRV
                     AAEIDFDPYEHGLTPHEVRRMDRAAQFAVVAARGAVADSGLEVETLDPYRIGVTIGSAV
                     GATMSLDQDYRAVSDGGRLDLVDHRYADPFFYGCFVPSSFAAEVARTVGAQGPSSVVSA
                     GCTSGLDSVGSAVELIREGSADVMVAGATDAPISPITMACFDAIKATTPRCDEPEHASR
                     PFDGTRNGFVLGEGAAVFVLEERESALSRGARVYAEIAGYATRSNAYHMTGLRPDGAEM
                     AEAITVALDEARMNPTEIDYINAHGSGTKQNDRHETAAFKRSLGDHAYRTPVSSIKSMV
                     GHSLGAIGSIEIAASVLAVQHNVVPPTANLHTPDPECDLDYVPLTARDQLVDAVLTVGS
                     GFGGFQSAMVLAQPERNAA"
     aSDomain        complement(4792..5958)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C4J65_11120_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="4.40E-53"
                     /label="C4J65_11120_PKS_KS.1"
                     /locus_tag="C4J65_11120"
                     /protein_end="391"
                     /protein_start="2"
                     /score="172.5"
                     /tool="antismash"
                     /translation="ITGLDVLAPGGVGVKNFWSLLSEGRTATRRITFFDPGQFRSRVAA
                     EIDFDPYEHGLTPHEVRRMDRAAQFAVVAARGAVADSGLEVETLDPYRIGVTIGSAVGA
                     TMSLDQDYRAVSDGGRLDLVDHRYADPFFYGCFVPSSFAAEVARTVGAQGPSSVVSAGC
                     TSGLDSVGSAVELIREGSADVMVAGATDAPISPITMACFDAIKATTPRCDEPEHASRPF
                     DGTRNGFVLGEGAAVFVLEERESALSRGARVYAEIAGYATRSNAYHMTGLRPDGAEMAE
                     AITVALDEARMNPTEIDYINAHGSGTKQNDRHETAAFKRSLGDHAYRTPVSSIKSMVGH
                     SLGAIGSIEIAASVLAVQHNVVPPTANLHTPDPECDLDYVPLTARDQLV"
     gene            complement(6386..6850)
                     /locus_tag="C4J65_11125"
     CDS             complement(6386..6850)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /locus_tag="C4J65_11125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /product="hypothetical protein"
                     /protein_id="AXL88817.1"
                     /transl_table=11
                     /translation="MTQLAATRGPGAGLVLLQTLAVLYTTGFVWTLQLMDYPMVARMRD
                     GASESYMAAHNNMFWKVLAPGLLVAGVTSVLLALVGPPTVPLWAALVMIGLLITIMVLS
                     GAVATPDRDSLAAHFSTPVHAHLLRVSWVRTTLFTVWSGLDAWLIWRLMR"
     gene            complement(6847..7551)
                     /locus_tag="C4J65_11130"
     CDS             complement(6847..7551)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151537.1"
                     /locus_tag="C4J65_11130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="AXL88818.1"
                     /transl_table=11
                     /translation="MTPSSPPAGARRPRGRRREADRNDERVLMAAHQAFAELGWNASVT
                     EIARRAGLGMGSLYRRYRGKEELAQHLRIVGMEHLTKVAQAAALEQPNGWSALVRFMND
                     AVSSSAGTLLPLIGGVLPATHGVEAATTRLHDAVEPIVARARDEGSLRADIGSADLVLL
                     LVHLKAKLPAPPDRARQLRFRYLQMALHGMRSGPDPEPAGPVFPAPDWRELRALWHALP
                     EPCRPTEPGGRP"
     gene            complement(7605..8531)
                     /locus_tag="C4J65_11135"
     CDS             complement(7605..8531)
                     /codon_start=1
                     /gene_functions="resistance (resist) ClassB (Score: 87.4;
                     E-value: 6.1e-27)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     56.8; E-value: 3.6e-17)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C5-C14
                     (Score: 424.7; E-value: 3.9e-130)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019524862.1"
                     /locus_tag="C4J65_11135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="AXL88819.1"
                     /transl_table=11
                     /translation="MPDVRDAPATPVYALREIEESVYAYLQPDGGWCLNNAGLVLGSSG
                     PLLIDTAATEKRAALLRDTVRALDSRPVDILVNTHSHGDHTFGNHLFPDATVVAQEKAA
                     AEMAEYGTALRGLWPEVTWGHVEAGVPDVVFKDHLVVPGTGRRVELLHLGPGHTAGDAV
                     VWLPDQRVLFAGDLVFSGATPFVLMGSIEGSLRVLDQLRALEPLHVVPGHGPVGGPELL
                     DLNAGYVRWVRDLARQGLADGAEPLAVARSVGLGPYGHLLDGERIVGNLTRAYAEERGT
                     PPAAPLDVTAAFGEMIEFHGSRPTCSA"
     misc_feature    complement(8487..8489)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8533..8856)
                     /locus_tag="C4J65_11140"
     CDS             complement(8533..8856)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:PF03992.14"
                     /locus_tag="C4J65_11140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="AXL88820.1"
                     /transl_table=11
                     /translation="MPEEWRIVMIVLVNVFEINDSEENFERAFCAVSEVMRRQGGFGRH
                     RLVRSESTPTTYINVAEWTDERSLRAALAHPEVSRRVRTLMRSATAVPQICRPVLDASR
                     QEA"
     gene            9047..9868
                     /locus_tag="C4J65_11145"
     CDS             9047..9868
                     /codon_start=1
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     273.9; E-value: 5.6e-83)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:PF00486.26"
                     /locus_tag="C4J65_11145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="AXL88821.1"
                     /transl_table=11
                     /translation="MEIGILGPLTVHSGDREAAPSAPKPRQLLAMLAVRAGQAIAMDLL
                     VDELWESSPPRSAVTAVQTYIVTLRRSIAESLRITTDEAADKVLQYTGWGYRLQPGQGA
                     HDALVFTRYAAQGQQALVEGDYGRASLLLRRGLSMWRGPALADVPVGTQLLAHRTSLDE
                     RRMSAVEQRIEADLQMGLHQELVGELSGLCIQHPLHENMHSLLMVSLYRAGRPRKSLET
                     FQKLRQNLRAELGMDPSGRTKAIHHAILSGDADGDSNLFRRGAAPLKLAAD"
     misc_feature    9275..9277
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9979..11367)
                     /locus_tag="C4J65_11150"
     CDS             complement(9979..11367)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 425.2; E-value:
                     4e-129)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645199.1"
                     /locus_tag="C4J65_11150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="AXL88822.1"
                     /transl_table=11
                     /translation="MAITSIAAFMVSLDQLVVTTALPKIREDLHTDVQGLEWVVNAYTL
                     TFAVLLLTAAAVADRFGRRRLFGIGLALFTAASAVAAMSSGIGVLVAARAIQGLGAAIV
                     LPLTLTLLSAAHPPEKRGAALGVWGAVAGLAVACGPVVGGFITESASWQWIFWINVPIG
                     VAMLAFVGRGLAESRGPNSRLDLPGTALGSLGLLGVVFAIERGQSAGWSSAQTWASGLG
                     GLVLLAGFLAWERRAPAPMLPMRLFRSRTFSVVNGLSLFMFFGMFGSIFLVTQYLQTVQ
                     GSSPLGAGLKMLTWTGMVLFAAPLGGGLSDRIGGRPILVAGLGLQAVGLLWLAVVADST
                     TSYGALVPAFVCNGIGMGLYFGPTGNIVMGSVARSEEGIASGTNNAIRELGGVLGVAVL
                     ASVFTAHGGYDTPEHFADGLHYALWLGFPLVALGAVTAAFLPGRRAAAGSGDETVPVPE
                     HAAV"
     misc_feature    complement(11035..11037)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11309..12247
                     /locus_tag="C4J65_11155"
     CDS             11309..12247
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 85.5; E-value: 4e-26)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:PF13463.4"
                     /locus_tag="C4J65_11155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="AXL88823.1"
                     /transl_table=11
                     /translation="MVTTSWSKETMNAAIDVMAMVGPARPMVSGCAAVAVDLAMTVRLL
                     KEGRLRTGGGRLPAPGSGSSVHRCTNLASARDTEGSRVKQLARKPSGGDTRWRMVSMST
                     VEGSPSGAVPPEVLRPGFQAWLSLVHTYGSVAKVLDRRLTRDLEMSLAWFEVLTLLLTA
                     ADGRRRMLELSQLLVVSKASVSKLVDRMERAGLVRRETTEQDRRAVYAVITPSGEEAIR
                     KALPLQIANVDECFSGLLDEQDMDDLVRILGKVISHYEGVGPSTPSTPSSALLNAEAPA
                     ADRPVPAGSPADGADVERKGRPAPHPLRKRQ"
     misc_feature    11564..11566
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12176..13072)
                     /locus_tag="C4J65_11160"
     CDS             complement(12176..13072)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     87.5; E-value: 1.4e-26)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606965.1"
                     /locus_tag="C4J65_11160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="AXL88824.1"
                     /transl_table=11
                     /translation="MTDSATTGPADAGLWRVDGRCIDCDVARQLAPGNTAQRDGTTVVT
                     RQPRTADEEAGLWRAALACPVAAVRPPREATAPTGLLPSRIEDEVYLCGYNSKETFGAN
                     AYFVRRPEGNLLIDAPRFSRAVAARYEELGGVSRILVTHRDHVPHVARYAQHFGAPVWI
                     HEGDSASAPFATEILRGSAPETVQRGVVALPVTGHTPGSTVYLVDDRFCFTGDTLYWSR
                     DQEDLEVFETVVWHSRQELLESVRRMAAQARFEWVLPGHGDRRRLPADEMTTRLLALAQ
                     RMRGRPALPLDIGAVRW"
     gene            complement(13125..14789)
                     /locus_tag="C4J65_11165"
     CDS             complement(13125..14789)
                     /NRPS_PKS="Domain: AMP-binding (43-441). E-value: 2.1e-81.
                     Score: 265.4. Matches aSDomain:
                     nrpspksdomains_C4J65_11165_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     328.9; E-value: 7.6e-100)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:PF13193.4"
                     /locus_tag="C4J65_11165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="AXL88825.1"
                     /sec_met_domain="AMP-binding (E-value: 5.7e-85, bitscore:
                     275.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDRTSAEGAVVTDAQPEGRTAGPAPGPGLGPGSAGRVDGLLAAA
                     AAAHPDRPAVIGETRLTFADLDARASRYAEALRPLIAGRGAPVVVSSAPHPEFMAAYYG
                     AIRAGAVAVPMNPLLPDPAVERVIEQSGAVVALLAPQVFTRVEASRPRLPRLAHVLRLW
                     DDAGEGGVLVAAGPGPTSTARAGGPASVTPVADGSDPAVVMFTSGTTGPSKGVAVSHHA
                     VRTNAAQFGDAHGIDDRSVVMCHLPIVSPMHMNAAVRAGACQLLCPDPDIRSSVRMANA
                     HRATHYYSLPVRLARLASAPELGGLAFDTVRMIAAGNQTIAAHIIKGLSERFGVPVFQG
                     YGLTESTHLAHTDGPVEPRPGSAGPPVAGSRSRIVDTVTGRVRGPGEVGELQINGPQLM
                     TGYVNRPELSPFDDEGWFATGDVARLDEDGYLYVLDRLADVFRHDGLLVSPSRLERALE
                     AHPDVVEAGVADQPDGSRGRTPVAFVVPKDARSDSGPMQCGALLAAVNSSLEAHERIRH
                     AVVTDAVRRSATNGKVDRKALREELARRPAPEVLDEG"
     aSDomain        complement(13467..14660)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C4J65_11165_AMP-binding.1"
                     /evalue="2.10E-81"
                     /label="C4J65_11165_AMP-binding.1"
                     /locus_tag="C4J65_11165"
                     /protein_end="441"
                     /protein_start="43"
                     /score="265.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="AAAAAHPDRPAVIGETRLTFADLDARASRYAEALRPLIAGRGAPV
                     VVSSAPHPEFMAAYYGAIRAGAVAVPMNPLLPDPAVERVIEQSGAVVALLAPQVFTRVE
                     ASRPRLPRLAHVLRLWDDAGEGGVLVAAGPGPTSTARAGGPASVTPVADGSDPAVVMFT
                     SGTTGPSKGVAVSHHAVRTNAAQFGDAHGIDDRSVVMCHLPIVSPMHMNAAVRAGACQL
                     LCPDPDIRSSVRMANAHRATHYYSLPVRLARLASAPELGGLAFDTVRMIAAGNQTIAAH
                     IIKGLSERFGVPVFQGYGLTESTHLAHTDGPVEPRPGSAGPPVAGSRSRIVDTVTGRVR
                     GPGEVGELQINGPQLMTGYVNRPELSPFDDEGWFATGDVARLDEDGYLYVLDRLADVF"
     CDS_motif       complement(13563..13637)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C4J65_11165_0002"
                     /evalue="3.50E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="C4J65_11165"
                     /protein_end="409"
                     /protein_start="384"
                     /score="28.9"
                     /tool="antismash"
                     /translation="PGEVGELQINGPQLMTGYVNRPELS"
     CDS_motif       complement(14130..14189)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C4J65_11165_0001"
                     /evalue="1.40E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="C4J65_11165"
                     /protein_end="220"
                     /protein_start="200"
                     /score="23.8"
                     /tool="antismash"
                     /translation="AVVMFTSGTTGPSKGVAVSH"
     gene            14988..15518
                     /locus_tag="C4J65_11170"
     CDS             14988..15518
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:PF13577.4"
                     /locus_tag="C4J65_11170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxylacyl-CoA dehydrogenase"
                     /protein_id="AXL88826.1"
                     /transl_table=11
                     /translation="MAPPNAPRGHPVTSDSIAPVATPFETPFDTPDTAVDIALYHDIQQ
                     FYVRQMHAGDGGDFTAWAASFTEDAVFVSNGLPAPVAGRAAIDAATRAGAAARAERGAT
                     HRHVVTMLDVRPKGEHRAEARSYVLVVEAIRGGATTVHVSTVCEDRLVLREGRWLVEER
                     RVTRDDRPKRTSA"
     gene            15543..16013
                     /locus_tag="C4J65_11175"
     CDS             15543..16013
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:PF13577.4"
                     /locus_tag="C4J65_11175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="AXL88827.1"
                     /transl_table=11
                     /translation="MPRDTATDTHTDTHTDVGTQAVVLIRLQQFYAAQVHALNDGDHVT
                     YRGTFTTDAEFVLGGAPAPLHGAEAITEHSRSLASRRSESGDVQRHHVTMTGLVNRPGT
                     AIAAGSRTLITTTTPHGATVVTASTTCLDEFAVEGGVLRIRRRVVVRDGARG"
     gene            complement(16083..16670)
                     /locus_tag="C4J65_11180"
     CDS             complement(16083..16670)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017536725.1"
                     /locus_tag="C4J65_11180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="AXL88828.1"
                     /transl_table=11
                     /translation="MAGAVPSEPRLRADARRNSEQIRSAAIGAFQGQGLTVPLEEVAKA
                     AGVSKATIFNRFGGRVGLIEAVIEEVVASELFAVVDRTRTIDDGGERIAYYLTAIRDLQ
                     YRQPAFNDVLLQTYPHSEQLMEICRVGSGANEEIVAAARARGALRPEFTAGDLHALVLD
                     NALALKHGERPAREDYDRRTRYLLDGIRPASG"
     gene            16793..17647
                     /locus_tag="C4J65_11185"
     CDS             16793..17647
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 197.6; E-value: 5.3e-60)"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388473.1"
                     /locus_tag="C4J65_11185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="AXL93232.1"
                     /transl_table=11
                     /translation="MIVVTGATGGLGGATVEHLLRRVPADRIGVSVRDTAKARHLADRG
                     VRVRQGSYEDPAALRDSFAGAEQVLLVSGNDPAADIVGLHRNAVEAAVAAGVRRIVYTS
                     QQGAVPGNPYPPSDLHIATEAILGDSGVAWTALRNGAYGPLDQVLGPWQRTGVIAKPED
                     GPVPYTDRDDIAEATAVVLAGDRPLDGPVNLTAPTAVTFDDLARTASGLTGRSVERVVL
                     DDDQWIADHIATGVPEQMARLMLTYYQAARAGYFAEADPLLAELLGREPRTVADRLAAD
                     MAA"
     gene            17775..18341
                     /locus_tag="C4J65_11190"
     CDS             17775..18341
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575782.1"
                     /locus_tag="C4J65_11190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="deaminase"
                     /protein_id="AXL88829.1"
                     /transl_table=11
                     /translation="MRRVTYSMNVSLDGYIVDASGDIDWSDPDEAVFRYWTDELRETGA
                     HLLGRRLYETMLYWETAEQDESLGAAELEWAALWKALPKVVFSRTLTTVRGTNTRLASG
                     TLAEEIERWRAEPGEGDISIGGATLAAEASDAGLIDEYRAVVHPVLVGGGTPFFPHHGR
                     RVNLELVESRTFGRNVILLRHHVAR"
ORIGIN
        1 aggaggggta ccggcagacc ggcgaacgcc cagcacgacg ccccgaccgc cgggcggccc
       61 ggcgggcctg tgggcggcgc cgtccaccgg ccgtggccgc tcagttgacg ctgcgccaga
      121 tgtggggctc cggctcttcc tcgtgctcct gcgtgtgcgg gccgtcgagg tcgtgtccct
      181 cgccggactg ccgcggatgc tcttccatgg gcacgctgct cccctccgcc ccgtgccgcg
      241 cggctgaatt ggtcatgttc cttccaagcc cagccgccac cggtgagcgc cgggagcgaa
      301 gatgctcaat gccaccagca gggggtgctc gtcgcactcg gtggcccggg gcggcgcgca
      361 ctgtgctttc ggcggccgcg caggggcgac gcctgcgatc tccgtgatgt ccgtgatgtc
      421 ctgtgtcatg tccgggattc cctccctacg ccgtggtgtc gcatggactc ctccagaaag
      481 ccgagggcct tcaggtggta ggcgcgggcc gcccagccga ggctgatgtt gtggcccgcg
      541 tcgggctggt gctcgatcac gacacgcggg gccgcgctca accgggaccg caagcggtcc
      601 agggccggcg ggtcgtgccg ccaccacgtc tcgtactcgg cgaaggtgaa ccgcaccggc
      661 accctgatcc gccccgcgag ccggccgaac tccgcgggcc accgcgcggc gtccgcgagt
      721 tcccccggtg gcacgcgggc cacgacggcg gcccccgacc ggaaggtgcc cggcggatac
      781 agccgcagcg gcccccagct gcgccgccat ccgccgtccc gtgtgccggg ctcggtgggc
      841 ggtgccgtgt aggcgtcgcc gcagcccgag acgtccaccc cgagcagtgc gggcagcgtt
      901 ccctccgccg ccatccgcag cgccggcttc ccgccgaagg agtgggccag gaggaagagt
      961 ccggcgccgg tgtcgtaccg gtccgcgaga tcgcccagcg cggccgtcag cgtggccgcc
     1021 tgctccgccg ccgtctgccc acgcggcagt tcggccgagg acagcccgta gccggggcgg
     1081 tcgactgcca ccgccgcgaa gcccagatcc gcggcgagcg tcagcagcga ggtctccggc
     1141 cgggtctgcc cgtgaaagta cgcggcgctc ataccggcgc cgtgcagggc gacgacggtc
     1201 gcccgcggcg gcgcgtacag ggggcgggcc agcagtgcgg acacggtaat gccgcccgct
     1261 tgcaacgtga tccgccctac cttcgcggac accgccgccg gcgccgtcgg cggggctgtc
     1321 ggcggggccg tcggcggggc tttcggcggg gctttcgtca tgaacggctg tccacggcca
     1381 ggccctccgc gtgcgccttg gcgagggcga gcgtcgccag actgttggtg ctgagcgccg
     1441 tacggacgtg gtcgacggcg tcctggacgg tcgcgtcgga acccagcacc ttctcgatgg
     1501 cgtcggtccg gaccgtgaag gtgtgctgcg aggacgccgt gacatcgcct cgctcgtcgg
     1561 cagggccgaa ggtccagtgg ccggtgtgca gggagatcag ggcggggagg gtgatctgct
     1621 tgtacgcgat ccggtgcggg gcgagcccca cccggtgtga cttcgtggtg tgcgaggtgc
     1681 cgtccttggc catggtgtcc atctccaggg tctgcacccc cggctccggc tcctccaggc
     1741 gcaccctgag tacgtgcggc agccgttcgg tccacaggtc ggcccggttg acgaagtcgt
     1801 acacgacacc gacgtcgccc cggatccgga ccgagtcctc gaaggagcag gtcagttcgg
     1861 cgaccgcggt gccggactcg gcgaccgcct tcagggacgc cagctcggag cgggaatttc
     1921 ggtccactac gtcgtcgagc cacggcaggc tctccgcgtc gacggcccgg tagtcgtgca
     1981 ggaggcgcac cagcgaccgg ccggcgggca gggcgtcgat ctgccaggtg ccgcccatct
     2041 gcgccacggg cggggtgctg acctcttgcc ggaaccggat ccgcagacgt tccgggtcca
     2101 ggctccggtg ggacgtccag ttcttgacgg tgtcgccggc cgtcgcccag atgcggatgc
     2161 gctcttcgcg ctcaccgcgt tcgacatggt cggcgtggat ggtcggggga aacagctgcg
     2221 gccacttctc cgcgtgggcc agcatgcggt acacggcctc ggcctcggcc tcgatctcga
     2281 tctcgtgggc ggactcgtgc ggttcggacg gcatggagct ctcctcgtgg gtcggtcggg
     2341 tgcgggcggc ggggtcagaa gttgccgagg ccgccgcaga cgttcagcgc ctgggaggtg
     2401 atggacgccg ccgtgtcgga gaccaggtag ccgaccaggc cggcgacttc ctcgggagtc
     2461 gagtaccggc ccagggggat cttggcctgg aacttctcca ggatcgccgc ctcggaggca
     2521 ccggagaggc gggagtagtt gtgccggacg cgttcggcca tcggcgtctc tacgtagccg
     2581 gggcagacgg cgttgaccgt gattccggtc ggcgccagtt cgttgccgag tgccttggtg
     2641 aagccgacga cgccgtgctt ggacgcggag tagggggcgc cgagcacgac gccctgcttg
     2701 ccggcggtgg aggcgatgtt gacgatgcgg ccccagtcct tgtgccgcag tccgcccgcg
     2761 gtgaggacct ccctggtcag gcggaacaca ctgttgaggt tggtgtcgac gacgtcgtcc
     2821 cacacctcgt cggggacgtc ggcggtgacc ccgcctccgc tgatcccggc gttgttgacg
     2881 agcacgtcga ccgtgccgaa ctggtcgacg gctgcccgga cgtagccgtg tacggagtcg
     2941 gcggaccgta cgtcgagaac cacaccgtcg acgtcgaact gctcctcctg gagctgcttg
     3001 accgtcgcga ggaccttgtc ctcggtgcgc gagccgatga acacccgatg cccccggccg
     3061 gccagcagcc gggcgaccgc gagaccgatg ccgctggtcg ctccggtcac caggacgacc
     3121 cgctgctgct cgtgctgtgt catgtcctga agtcccttcg tgtcgtcgtt cgtgggtcag
     3181 gcggcgggcg cgaccagatg tgcggtgacg gcgtcgagaa gggcggcggg ggtggtggcg
     3241 tcgcccacca cggactcgtc cagctcgatg ccgtactcgc gttcgatccg gctggccgtc
     3301 tccagcagcg cgagcgagtc gtagccgagg tcgctgaact cggtgtccag gatgctcccg
     3361 tccaggtcga tgccctcggg ggcgccggac ccctccagga gaatccgctt gaggtcgtcg
     3421 atggtgaaaa ctccgtgcga catgaactgc ctttcttctg gggtgaatcg gtgtgcgggt
     3481 cggtgcgcgt cgatggggtg cgggggccgc ccggcggtca ggagcgcacg accatggccg
     3541 agttgaagcc ctcgtgaccg cgtgcgacga ccagcgccgt acgcagttcg gcggcgcgtg
     3601 gctgggaggt gaccaggtcg aggccgtatc ggctcgcggg ctcgatgtgg gcggtcggcg
     3661 ggatcacccc gtccgccagc gcgaggaacg ccgcggcgag gtccagggag gcggcaccgg
     3721 cgtacaggcg gccggtcatc gtcttgggcg cggtcaccgg gaccccgttc ggaccgaaga
     3781 cctcgacgag ggcctcggcc tcgacgcggt ccagctcggg atcagcggcg gcgtccgcga
     3841 agaccacgtc cacgtccgac gggtgcaccc gtgcgtcgtc gagggcgagt tccagggcct
     3901 tgcgcaggcc ggactcccgc ccgtcgaagg tggccgcgta tccggcgatc tctccgtaca
     3961 cccgggcgcc gcgggcgcgc gcggactcgg cggactccat gacgagcagc gcaccgccct
     4021 cgcccgccac atgaccggcg gcccggtcgt cgaagggcag ataggcgtgg gtgggctcct
     4081 cctcggtgct gagtcgaccg ctggtgtgca gcccgaccca cccccaggag cacagcagcg
     4141 cgtccaccgc gccggccacg acgagcgagg tgcccttgcg gatgtgccgc cgggcctggg
     4201 ccaccgcgtc cagaccgcct gcctggtcgg tcaccacgac gccgctgggg cccttcatcc
     4261 cgttgcggat ggagatctgt ccggtgttga ccgcgtagaa ccaggcgaac gactgatatg
     4321 cgctgacgta ctggccgccc ctgctccaca ggttcttcag ctcgttctgg ctgaactcga
     4381 atccgcccgc cgaactcgcg gtgatcacac ccatgtcgaa ctccgcgagt tcggcggggt
     4441 tcaccccggc gtccccgagg gcccagtcgg cggcgaccag cgagagccgg gtgccccggt
     4501 cggtctgcgg cagcagccgg ctcggcaggt gctccgccgc ctcgaatccg gcgatctccc
     4561 cggcgagctt ggccggatag ccggatacgt cgaagtgggt gagccggccg atgccgctct
     4621 tgccggccag tgtcgccgcc cagaagtcgc gggctccgag cccgttgggg gcggtcacgc
     4681 ccagccccgt caccactgcc gagaccgtca tgccgcgttc ctctccggtt gggccagcac
     4741 catcgcgctc tggaagccgc cgaagccgct gccgaccgtg aggacggcgt cgaccagctg
     4801 gtcgcgcgcg gtcaagggca cgtagtccag gtcgcattcg gggtcggggg tgtgcaggtt
     4861 cgccgtcggc ggcacgacgt tgtgctggac cgcgagtacc gacgccgcga tctcgatgga
     4921 gccgatcgcc ccgagcgagt gcccgaccat cgacttgatg gagctcaccg gggtgcggta
     4981 ggcgtggtcg cccaggctcc gcttgaacgc ggccgtctcg tgccggtcgt tctgcttcgt
     5041 tcccgagccg tgcgcgttga tgtagtcgat ctcggtggga ttcatccggg cctcgtcgag
     5101 agccacggtg atcgcttccg ccatctccgc tccgtcgggg cgcagccccg tcatgtggta
     5161 ggcgttgctg cgcgtggcgt accccgcgat ctccgcgtag acgcgggcgc cgcggctcag
     5221 ggcgctctcc cgctcctcta ggacgaacac cgccgcgccc tcgccgagca cgaacccgtt
     5281 gcgggtgccg tcgaacgggc gggaggcgtg ctcgggctcg tcgcagcgcg gtgtggtcgc
     5341 cttgatcgcg tcgaagcacg ccatcgtgat cggcgagatc ggcgcgtcgg tggcgccggc
     5401 caccatgacg tccgccgacc cctcccggat cagctcgacg gcgctgccga ccgagtcgag
     5461 ccccgacgtg catcccgccg acacgacgct gctcgggccc tgggcgccca cggtccgggc
     5521 cacctcggcc gcgaaggagc tcggtacgaa gcagccgtag aagaacggat ccgcgtaccg
     5581 gtggtcgacc aggtcgagcc ggccgccgtc gctgaccgcg cggtagtcct ggtccaggct
     5641 catggtggca cccaccgcgc tgccgatggt cacgccgatc cggtaggggt cgagcgtctc
     5701 cacctcgagg ccgctgtcgg cgaccgcacc acgcgcggcg accacggcga actgcgccgc
     5761 ccggtccatc cgccgcacct cgtgcggggt cagaccgtgc tcgtacggat cgaagtcgat
     5821 ctcggcggcc acccgcgacc ggaactgccc ggggtcgaag aaggtgatcc tcctggtcgc
     5881 cgtacggccc tcgctcagca gggaccagaa gttcttgacg ccgacgccgc cgggcgccag
     5941 cacgtccagg ccggtgatga ccacccggcg gggtacgtgg gcgcctcgtc ccggctgtgt
     6001 tgcgcggcgg gcgtcccgtg ccgggtccgt cgcagacata tcagctgcct ttcgtggagg
     6061 ggttccccgg catgacacgg cacggcattc ggctgccgga tacgagcggg gaacgtcgtg
     6121 gaggggccgt ccgcagtgac atcggatcgg ctgcaacgaa cctccggtcg gcccctcaag
     6181 ggccgatcaa ggacgggcca aggaggtccc cgtggctgtc ggagtgcccc tgtgatctgg
     6241 tccgatccgc gcttgaacgg ttctgttgcc gttcttgagc ggtatgcgtc cgccccgttc
     6301 cccgtccgga cggcacgaag aggcggcgcg gaccgtgagg tccgcgccgc ccgggtgcgg
     6361 cggggcttgc gcccgtggtt cgggttcagc gcatgagccg ccagatcagc cacgcgtcca
     6421 gtccgctcca gacggtgaac agggtggtgc gcacccagct cacgcgcagg aggtgggcgt
     6481 gtacgggtgt ggagaagtgc gccgcgaggg agtcgcggtc gggggtggcc acggcgccgg
     6541 agagcaccat gatcgtgatc agcaggccga tcatgacgag agccgcccac agggggacgg
     6601 tgggtggccc gaccagcgcg agcagcaccg aggtcacccc ggccaccagc agtccgggag
     6661 cgagcacctt ccagaacatg ttgttgtgag cggccatgta cgactcggac gcgccgtccc
     6721 gcatccgggc caccatcggg tagtccatca gctgcagcgt ccagacgaat ccggtggtgt
     6781 agaggaccgc cagggtctgc aggagcacaa ggcccgcgcc cggtccgcgt gttgcggcga
     6841 gctgggtcat ggtcgtcctc cgggctcggt ggggcggcac ggctccggca acgcgtgcca
     6901 cagggctcgc agttccctcc agtccggggc ggggaagacg ggccccgccg gttccgggtc
     6961 cggtccggac cgcattccgt ggagagccat ctggaggtag cggaacctga gttgccgggc
     7021 ccggtcgggc ggggcgggca gtttcgcctt caggtggacc aggagcagca ccaggtcggc
     7081 cgagccgatg tcggctctga gggacccctc gtccctggcc cgtgccacga tcggctccac
     7141 ggcgtcgtgc agccgggtgg tggccgcttc gaccccgtgg gtggccggca gcacgccgcc
     7201 gatgagcggg agcagcgtac cggcgctgga cgagacggcg tcgttcatga agcggaccag
     7261 ggcgctccag ccgttcggct gctccagcgc ggcggcctgc gcgaccttcg tgaggtgctc
     7321 cattcccacg atgcgcagat gctgggccag ctcctccttt ccccggtatc tgcggtagag
     7381 actccccatc cccaaccccg cccgccgggc gatctcggtc accgaggcgt tccagccgag
     7441 ctccgcgaac gcctggtggg ccgccatgag cacgcgttcg tcgttgcggt cggcctcgcg
     7501 ccggcggccg cgcgggcggc gcgcgccggc cgggggcgag gacggcgtca tggcctcgtt
     7561 cctcctctcc tcgtccgggc gcgtcgcgtc gctcggtgcg gcgctcatgc ggagcaggtc
     7621 ggacgggagc cgtggaattc gatcatctcg ccgaaggcgg ccgtcacgtc gagcggagca
     7681 gcgggcggtg ttccccgttc ctcggcgtag gcgcgggtca ggttgcccac gatccgttcg
     7741 ccgtcgagca ggtgaccgta cggtccgagg cccaccgacc tcgcgaccgc caacggctcg
     7801 gccccgtccg ccaggccctg ccgggcgagg tcccgcaccc agcggacgta gccggcgttc
     7861 aggtccagca gttccggccc gccgaccggc ccgtgtcccg gcacgacgtg cagcggttcc
     7921 agggcccgca gctggtcgag cacccgcagg ctgccctcga tcgatcccat caggacgaag
     7981 ggagtggcgc cggagaagac gaggtcccct gcgaacagca cccgctggtc gggcagccat
     8041 acgaccgcgt cccccgccgt gtggccgggc cccaggtgca gcagttcgac gcggcggccg
     8101 gtaccgggga cgaccaggtg gtccttgaag acgacatcgg gcacaccggc ttcgacgtgt
     8161 ccccacgtga cctcgggcca cagccctcgc agcgccgttc cgtactcggc catctccgcc
     8221 gccgcctttt cctgggccac caccgtcgcg tccgggaaga ggtggttgcc gaaggtgtgg
     8281 tcgccgtggg agtgcgtgtt gacgaggatg tcgacgggcc gggaatcgag agcgcggacg
     8341 gtgtcccgca gcagcgcggc ccgcttctcg gtggcggcgg tgtcgatgag caggggcccg
     8401 gaactcccca ggaccagtcc ggcgttgttc aggcaccagc cgccgtccgg ctgcagatag
     8461 gcgtagacgg attcctcgat ctcccgtaac gcgtacacgg gtgtggcggg ggcgtctcga
     8521 acgtcgggca tgtcaggcct cctgtcgtga agcgtcgagg acggggcggc agatctgcgg
     8581 tacggccgtc gccgaccgca tcagggtgcg aacgcgccgc gagacctccg ggtgggcgag
     8641 cgcggcccgc agggaccgct cgtcggtcca ctcggcgacg ttgatgtagg tcgtcggcgt
     8701 gctctcggac cggaccagcc tgtggcggcc gaacccgccc tgccgtctca tgacctcgga
     8761 gaccgcgcaa aaggcgcgtt caaaattctc ctccgagtcg ttaatttcga acacattcac
     8821 aagaacgatc attacaatcc tccactcctc gggcatgaaa tgaccccgtg agctaggtca
     8881 ctgcggacca aaaccctccg ataaagattg acggttgacg cgttaactgt agactcgacc
     8941 catgatctga tcacgagtga ccacttcggc gattcacatc atctccgcac ccttcacaac
     9001 aacaagggag cggtgcgttc tgactactca tctctggggg gagagtatgg aaatcggtat
     9061 tctgggaccg ctcaccgttc actcggggga ccgggaagcg gcgcccagcg caccgaagcc
     9121 gaggcagctg ctggcgatgc tcgcggtccg tgcgggccag gcgattgcca tggatctgct
     9181 cgtggacgag ctgtgggaga gcagcccgcc ccgttcggcg gtgaccgccg tgcagaccta
     9241 catcgtgacc ctgcggcggt ccatcgccga gagcttacgg atcaccacgg acgaagcggc
     9301 cgacaaggtc ctgcagtaca cggggtgggg ctatcggctg cagccgggcc agggcgccca
     9361 tgacgccctc gtcttcaccc ggtacgccgc acaggggcag caggcgctcg tcgagggcga
     9421 ctacggcagg gcgtcgctgc tcctgcgccg gggcctgagc atgtggcggg gtcccgccct
     9481 ggccgacgtg ccggtcggca cccagctgct cgcccaccgc acctccctgg acgagcgccg
     9541 catgtccgcc gtcgaacagc ggatagaggc cgatctccag atgggcctgc accaggaact
     9601 ggtcggtgag ctttccgggc tctgtattca gcacccactc catgaaaaca tgcactccct
     9661 gctcatggtt tccctgtatc gcgcgggccg gcccagaaaa tctctggaaa cttttcaaaa
     9721 gcttcgacaa aatctcaggg ccgaactcgg aatggatccg tccggcagaa cgaaggccat
     9781 tcatcacgcg atcctctccg gagacgccga cggtgactcg aacctgtttc gccgcggggc
     9841 ggcacctctg aagctggccg ccgactgaag cctgccgtcg gatccgccac tccgtttccc
     9901 cgccgcacgc cggacaggct ggccgcctgt ccggcgtgcg gcgtgttccg ggcggcacgc
     9961 cgcaccggcc ggcgggggtc agaccgcggc gtgttcggga accggaacgg tttcgtcgcc
    10021 ggacccggcc gccgcccgcc ggcccggcag gaacgccgcg gtgaccgctc cgagggcgac
    10081 cagggggaag cccagccaga gtgcgtagtg cagtccgtcc gcgaagtgct ccggggtgtc
    10141 gtacccgccg tgtgccgtga agacggacgc cagaaccgcg acgccgagca caccgcccag
    10201 ctcgcggatg gcgttgttgg tgccggaggc gatgccctcc tccgagcggg cgacggaccc
    10261 catcacgatg tttccggtcg ggccgaagta cagccccatg ccgatgccgt tgcagacgaa
    10321 cgcgggcacc agggcgccgt aggacgtggt ggagtcggcc accaccgcca gccacagcag
    10381 gccgacggcc tggaggccga gtccggccac cagaatcggc cggccgccga tgcggtccga
    10441 gagtccgcca cccagtggtg cggcgaagag caccatgccg gtccaggtca gcatcttgag
    10501 cccggcgccc aggggggaac tgccctggac cgtctgcagg tactgcgtga ccaggaagat
    10561 cgagccgaac atcccgaaga acatgaacag cgagaggccg ttgactacgg agaaggtccg
    10621 gctgcggaac agccgcatgg gcagcatggg agcgggcgcg cgccgttccc aggcgaggaa
    10681 gccggccagc agcaccagcc cgcccaggcc gctggcccag gtctgcgcgg aggaccagcc
    10741 ggcgctctga ccgcgctcga tggcgaagac cacgcccagc agccccaggc tgcccagagc
    10801 cgttcccggc aggtccagac gggagttggg accccggctc tcggcgagtc ccctgcccac
    10861 gaaggccagc atggccacac cgatcggcac gttgatccag aagatccact gccaggacgc
    10921 ggactcggtg atgaatccac cgacgacggg cccgcaggcg acggcgaggc ccgccacggc
    10981 gccccacacg cccagagcgg cgccacgctt ctccggcggg tgtgccgcgg acagtaacgt
    11041 caaggtcagc gggagcacga tggccgcccc cagcccctgg atggcacggg ccgccaccag
    11101 gaccccgatc cccgacgaca tggcggccac cgccgacgcc gcggtgaaca gcgcgaggcc
    11161 gataccgaac agccggcgtc gtccgaagcg gtccgccacc gcggcggccg tgagcagcag
    11221 tacggcgaag gtcagcgtgt aggcgttcac cacccactcg agaccctgga cgtccgtgtg
    11281 caggtcctcc cggatcttgg gcagggcggt ggtgaccacc agttggtcca aggagaccat
    11341 gaacgcggcg atcgacgtga tggccatggt ggggcccgcg cgtccaatgg tgtccggatg
    11401 tgctgctgtg gccgttgatt tggccatgac tgtccgactc cttaaagagg ggcggctgag
    11461 aacgggcggc ggccggcttc cggctccggg gagcggcagc tctgttcacc gatgtacgaa
    11521 tcttgcgagc gcccgtgaca cggaaggctc ccgcgtgaaa cagttagcta ggaaaccttc
    11581 cgggggcgac actagatgga ggatggttag catgtcaacc gtagaaggct ccccctcggg
    11641 agcggtcccg ccggaggtgc tgcgccccgg tttccaggcc tggctctcgc tggtccacac
    11701 ctacggctcc gtcgccaagg tcctcgaccg tcgcctcacg cgcgacctgg agatgtccct
    11761 ggcctggttc gaagtgctga cgctgctcct caccgcggcc gacggccgac gccgcatgct
    11821 ggagctgtcc cagttgctgg tggtctccaa ggcgagcgtg agcaagctcg tcgaccgcat
    11881 ggagcgagcg ggactggtac gcagggagac gacggagcag gaccgcagag cggtctacgc
    11941 cgtgatcacg ccgagcggtg aggaagcgat caggaaggcc cttccgctgc agatcgccaa
    12001 cgtggacgag tgcttctccg gcctcctcga cgaacaggac atggacgatc tggtccggat
    12061 cctcggcaaa gtgatctctc actacgaggg cgtgggaccg tccaccccca gcaccccgag
    12121 ttcggcgctg ctcaacgccg aggctccggc cgcggaccgg ccggtgccgg ccggatcacc
    12181 agcggacggc gccgatgtcg agaggaaggg caggccggcc ccgcatccgc tgcgcaagcg
    12241 ccagtagccg cgtcgtcatc tcgtcggcgg gcagccgccg ccgatcgccg tggccgggca
    12301 gcacccactc gaagcgggcc tgcgcggcca tgcggcggac cgactccagc agctcctgcc
    12361 tggagtgcca caccaccgtc tcgaacacct ccaggtcctc ctggtcgcgg gaccagtaga
    12421 gggtgtcgcc ggtgaagcag aaccggtcgt ccacgagata gaccgtgctg cccggggtgt
    12481 ggccggtcac cggcagtgcc accacaccgc gctgaaccgt ctcgggcgcg ctgccgcgaa
    12541 ggatctccgt ggcgaagggc gccgaggccg agtcgccttc gtggatccac accggcgccc
    12601 cgaagtgctg tgcgtagcgg gcgacatgag ggacgtggtc gcggtgcgtc accaggatcc
    12661 gggagacgcc tcccagctcc tcgtaccgcg cggcgaccgc tcggctgaag cggggcgcgt
    12721 cgatcagcag gttcccctcc ggccggcgga cgaagtacgc gttggcgccg aacgtctcct
    12781 tcgagttgta tccgcacagg tacacctcgt cctcgatccg cgaggggagc agccccgtcg
    12841 gcgccgtcgc ctcccgcggt ggacgcacgg ccgcgaccgg acaggccagg gccgcccgcc
    12901 agaggccggc ctcctcgtcg gcggtccggg gctggcgggt gacgacggtc gtgccgtcgc
    12961 gctgcgcggt gttcccggga gccagctggc gggcgacgtc gcagtcgatg cagcggccgt
    13021 cgactcgcca gagcccggcg tccgccggcc cggtggtggc ggaatccgtc atcggtcagt
    13081 actccttgtc acagacgtcc ggcgcgcacg tgcggttcga gcggtcaccc ctcatcgaga
    13141 acttccggtg ccggccgtcg cgccaactcc tcgcgcaggg ccttgcggtc cactttgccg
    13201 ttggtcgcgg accgtcgcac ggcatccgtc accacggcgt gccggatccg ctcgtgcgct
    13261 tccagcgagg agttgacggc ggccagcagc gcaccgcact gcatcggacc ggagtcggac
    13321 cgcgcgtcct tggggacgac gaaggcgacc ggcgtccgcc cgcggcttcc gtccggctgg
    13381 tccgccaccc ccgcctcgac cacgtcggga tgcgcctcca gggcccgctc cagacgcgac
    13441 ggcgacacca ggaggccgtc gtgccggaac acgtcggcca gccggtccag gacgtagagg
    13501 tagccgtcct cgtccagccg ggcgacgtca ccggtggcga accacccctc gtcgtcgaac
    13561 gggctcagct cgggccggtt gacgtagccc gtcatcaact gaggcccgtt gatctggagt
    13621 tcgccgacct ctccgggccc gcggacccgt ccggtcaccg tgtcgacgat gcgggaccgg
    13681 ctgcccgcca ccggcggccc cgcggatccg ggacggggct ccaccgggcc gtcggtgtgg
    13741 gcgagatggg tggactccgt gaggccgtac ccctggaaga ccggtacccc gaaccgctcc
    13801 gacaggccct tgatgatgtg cgccgcgatc gtctgattgc ccgcggcgat catccgtacc
    13861 gtgtcgaagg ccagaccgcc tagctccggc gcgctcgcca gccgcgccag gcggaccggg
    13921 aggctgtagt agtgggtggc acgatgtgcg ttggccatgc gcaccgacga ccggatgtcc
    13981 gggtccgggc acagcaactg gcaggcgccc gcccgcacgg cggcgttcat gtgcatgggc
    14041 gacacgatcg gcaggtgaca catcacgacc gaccggtcgt cgatcccgtg cgcgtccccg
    14101 aactgggcgg cgttggtgcg gacggcatgg tgggagaccg ccactccctt ggacggtccg
    14161 gtcgtaccgc tggtgaacat cacgacggcc gggtccgacc cgtccgccac gggggtgacg
    14221 gacgcggggc cgccggcccg tgcggtgctc gtgggccccg gtccggcggc caccagtact
    14281 cctccctccc cggcgtcgtc ccacagccga aggacatggg ccagccgcgg cagccggggc
    14341 cgcgacgcct cgacccgggt gaagacctgc ggggcgagga gggcgacgac cgcgccggac
    14401 tgctcgatga cacgctcgac ggcgggatcc ggcagcagcg ggttcatcgg aaccgcgacg
    14461 gcacccgccc tgatcgcccc gtagtaggcg gccatgaact ccgggtgcgg cgccgaggac
    14521 accaccacgg gggcgccccg gccggcgatc aacgggcgca gcgcctccgc gtaccgggac
    14581 gccctcgcgt cgaggtcggc gaacgtcagc cgggtctccc cgatcaccgc cggccggtcc
    14641 gggtgtgccg ccgccgctgc cgcgagcagt ccgtcgaccc ggcccgcgct tccgggtccg
    14701 agcccgggtc cgggtgcggg tccggctgtt cgcccctccg gctgggcgtc ggtgacgacg
    14761 gctccctcgg cggatgtccg atccagcatc tgtcttcctc ctggccttcc gaacgatgct
    14821 gccgcgtccg cgtgcccgac agggcaggcg gcagcacccc ggacgctgct gccaccggct
    14881 caagccgggg ccaaggccgg gtcaacgcag gttccacgag gccaggtcca ccgccccggc
    14941 ccaccttgac cgagggttga gcggaccttg agagacgtca ccggagcatg gcgccaccga
    15001 acgcaccgag aggacaccca gtgaccagcg actccatcgc ccccgtcgcc acccccttcg
    15061 aaaccccttt cgacaccccc gacaccgccg tcgacatcgc gctctaccac gacatccagc
    15121 agttctacgt ccgtcagatg catgccgggg acggcggtga cttcaccgcg tgggcggcca
    15181 gtttcaccga ggacgccgtc ttcgtctcca acgggctccc cgctccggtg gccgggcgcg
    15241 ccgccatcga cgccgcgacc cgcgccggtg cggccgcccg cgccgaacgc ggcgccaccc
    15301 atcggcacgt ggtgaccatg ctcgacgtcc ggccgaaggg cgaacaccgt gccgaggccc
    15361 gctcgtacgt cctggtcgtg gaagcgatcc ggggcggcgc cacgacagtg cacgtcagca
    15421 ccgtctgcga ggaccggctc gtgctgcggg aaggccggtg gctcgtcgag gaacgccggg
    15481 tcacccggga cgaccgcccg aagcggactt ccgcctgaac cgtcgccctg gaggcccatc
    15541 ccatgccccg cgacaccgcc accgataccc acaccgatac ccacaccgac gtcggcaccc
    15601 aggccgtcgt actcatccgt ctgcagcagt tctacgcggc ccaggtacac gccctcaacg
    15661 acggcgacca cgtcacctac cgcggcacct tcaccacgga cgccgaattc gtcctcggcg
    15721 gcgccccggc tccgctgcac ggagccgaag cgatcaccga gcacagccgg tcactggcat
    15781 cccggcgatc ggaatcggga gacgtccagc ggcaccatgt caccatgacc ggcctggtga
    15841 accggcccgg caccgccatc gccgccgggt cccgcactct catcaccacg acaacaccgc
    15901 acggcgcaac cgttgtcacc gcgagcacca cgtgcctgga cgagttcgcc gtggagggcg
    15961 gcgtcctgcg tatccgacgc agagtcgtcg tccgtgacgg agcccgtggg taggcgacga
    16021 cggtcaccgc cgccgggccg cgtgtcacgg ccgcctgacc cacacgtcga cgcggagcga
    16081 actcacccag acgctggcct gatgccgtcc aggaggtacc tggtgcggcg gtcgtagtcc
    16141 tcccgggcgg gccgctcgcc gtgcttgagg gcgagggcgt tgtcgaggac gagtgcgtgg
    16201 aggtcgcccg ccgtgaactc cggccgcagc gcgccccggg cccgcgccgc tgcgacgatc
    16261 tcctcgttgg ccccgcttcc gacccggcag atctccatga gctgctccga gtgcggatac
    16321 gtctgcaaca ggacgtcgtt gaaggcgggc tggcggtact ggaggtcgcg gatcgcggtg
    16381 aggtagtacg cgatccgctc gccgccgtcg tcgatggtcc gcgtgcggtc gacgacggcg
    16441 aacagctcac tcgcgacgac ctcctcgatg acggcctcga tgagcccgac ccgcccgccg
    16501 aaccggttga agatcgtggc cttgctcacc cctgccgcct tggcgacctc ctccagcggc
    16561 acggtcaggc cctgcccctg gaaggcgccg atcgcggcgg agcggatctg ctcggaattg
    16621 cgccgcgcgt cggcccgcag ccggggttcc gaaggcaccg caccggccat ggccctcacc
    16681 gtcccttcct gtcctcacca tcacaacttg actcgtcgag tcagcttacc tacggtcgtc
    16741 ggcagaagag aaggtgaccc ctgtggtcaa cttacgcggg aaggccaaga ccatgatcgt
    16801 tgtgaccggc gccaccggtg ggctgggcgg cgccaccgtc gagcacctcc tcaggcgcgt
    16861 acccgccgac cggatcggcg tcagcgttcg cgacaccgcc aaggcgcggc acctcgccga
    16921 ccgcggcgtg cgcgtgcggc agggctccta cgaggacccg gccgcgctgc gcgactcgtt
    16981 cgccggtgcc gagcaggtcc ttctggtctc cggcaacgac ccggccgccg acatcgtcgg
    17041 cctgcaccgc aatgccgtcg aagccgcggt cgcggccggc gtccggcgga tcgtctacac
    17101 gagccagcag ggcgccgtcc ccggcaaccc gtacccgccg tcggacctcc acatcgccac
    17161 ggaggcgatc ctcggcgact ccggagtcgc ctggaccgca ctgcgcaacg gcgcctacgg
    17221 cccgctcgac caggtcctcg gcccgtggca gcggaccggc gtgatcgcca agccggagga
    17281 cggccccgtc ccgtacaccg accgtgacga catcgccgag gccaccgcgg tcgtcctcgc
    17341 cggtgaccgt cccctcgacg gcccggtgaa cctcaccgcg ccgaccgccg tcaccttcga
    17401 cgacctcgcc aggaccgcct ccggcctcac cggtcgcagc gtcgagcgcg tagtcctgga
    17461 cgacgaccaa tggatcgccg accacatcgc gaccggcgta ccggagcaga tggcccggct
    17521 gatgctcacc tactaccagg cagcccgcgc gggctacttc gccgaggccg accccctgct
    17581 ggccgaactc ctcggccgcg agccccgcac cgtcgcggac cggctcgcgg ccgacatggc
    17641 cgcctgatcg ccgatccggc caggtctacc tgcccctggc ggctgtgcgg tgcgcgccgc
    17701 acttccgaca cccgctgcgg cgcccgcccg gcggccgtac cgtcgaaccc aacggccacc
    17761 gaggagggct tccgatgcgc agagtgacct attcgatgaa cgtgtccctc gacggctaca
    17821 tcgtcgacgc gagcggcgac atcgactgga gcgacccgga cgaggcggtc ttccggtact
    17881 ggacggacga gctccgcgag accggcgccc acctgctggg gcggcggctg tacgagacga
    17941 tgctgtactg ggagaccgcc gagcaggacg agtcgctcgg cgccgcggag ctggagtggg
    18001 ccgcgctgtg gaaggcgctg ccgaaggtgg tgttctccag gacgctgacg acggtgcggg
    18061 gcaccaacac ccgcctggcc tccggcaccc tggcggagga gatcgagcgc tggcgggcgg
    18121 aacccggcga gggcgacatc tccatcggcg gcgcgaccct cgccgccgag gcctccgacg
    18181 ccggcctgat cgacgagtac cgggccgtgg tccacccggt gctggtcggc ggcggcaccc
    18241 cgttcttccc gcaccacgga cgcagggtga acctcgaact cgtcgagtcc cgcaccttcg
    18301 gccggaacgt catcctcctc cgccaccacg tggcccgctg acccaccccg
//
