BGC0001907 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001907 (Daldinia eschscholzii IFB-TL01)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS	1	58,609	High	chromane	PKS

BGC0001907 - Region 1 - T1PKS

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Location: 1 - 58,609 nt. (total: 58,609 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 58,610
Label		BGC0001907

Tailoring functions

Lyases: dehydratase

gene3: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

Ligases: synthase

gene4: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

gene5: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001907.2	1.00	PKS	chromane	Daldinia eschscholzii IFB-TL01
BGC0001254.3	0.77	PKS	ACT-Toxin II	Alternaria alternata
BGC0002192.3	0.75	PKS	FR901512	fungal sp. No.14919
BGC0002191.2	0.68	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001244.3	0.68	PKS	(-)-Mellein	Parastagonospora nodorum
BGC0001276.3	0.68	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001268.4	0.68	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0001273.3	0.66	PKS	asperlactone	Aspergillus ochraceus
BGC0001275.3	0.66	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001284.4	0.66	PKS	alternariol	Parastagonospora nodorum SN15

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001907.2	1.00	PKS	chromane	Daldinia eschscholzii IFB-TL01
BGC0001254.3	0.77	PKS	ACT-Toxin II	Alternaria alternata
BGC0002192.3	0.75	PKS	FR901512	fungal sp. No.14919
BGC0002191.2	0.68	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001244.3	0.68	PKS	(-)-Mellein	Parastagonospora nodorum
BGC0001276.3	0.68	PKS	6-methylsalicyclic acid	Aspergillus terreus
BGC0001268.4	0.68	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0001273.3	0.66	PKS	asperlactone	Aspergillus ochraceus
BGC0001275.3	0.66	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001284.4	0.66	PKS	alternariol	Parastagonospora nodorum SN15

Similar known clusters from MIBiG 4.0

Module view

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 58609:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

gene4: pk

PKS_AT (518..825): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Propionyl-CoA: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 82.5
Methoxymalonyl-CoA: 70.5
Malonyl-CoA: 53.0
Isobutyryl-CoA: 47.7
Ethylmalonyl-CoA: 40.6
Propionyl-CoA: 37.2
fatty_acid: 31.8
CHC-CoA: 23.5
trans-1,2-CPDA: 22.5
2-Methylbutyryl-CoA: 20.3
Benzoyl-CoA: 19.4
3-Methylbutyryl-CoA: 11.2
Acetyl-CoA: 5.4
inactive: 0.0

Link to PARAS substrate predictor