LOCUS       BGC0001917             17000 bp    DNA     linear   BCT 22-JAN-2019
DEFINITION  Streptomyces nigrescens HEK616 DNA, common biosynthetic gene
            cluster.
ACCESSION   BGC0001917
VERSION     BGC0001917
KEYWORDS    .
SOURCE      Streptomyces nigrescens
  ORGANISM  Streptomyces nigrescens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 16:32:38
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17000
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..17000
                     /collected_by="Hiroyasu Onaka"
                     /country="Japan"
                     /db_xref="taxon:1920"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces nigrescens"
                     /strain="HEK616"
     subregion       1..17000
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17000
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             149..1210
                     /codon_start=1
                     /note="unnamed protein product; orf1"
                     /protein_id="BBG06137.1"
                     /transl_table=11
                     /translation="MDDDIQLDVTGPVLVVGGYGTVGGDLARLAATSWPLLLTGRTPER
                     GAALAEEVGAAVRRWDLSDPEPFSAKVRAVISTVNDPEDRVLLAAIRGGVPYVDITRWT
                     ARLQRAVAVAAVNPPKAPVLLSSSWMGGVTALVAAALAAEVGGASAVEIAIRYDLKDRA
                     GTDSVEFMDRLGLDYEVTEGGQRRMIMPLSGAGHVAIGEHRTKVARIDTPEQFTLPLVL
                     GVDTALTRIGFSANSSTSTLLALKKTGFFRWGRGEKFQSTRRSMLYSPGEGGSACLRID
                     VRGRGGQRRTAVLTDPAGQAHLTALGGLLGLRRVLGEDGAAAPRGVVFPEMTPVPQDVV
                     AALEKAGVGVEVS"
     CDS             1207..1854
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 87.3; E-value: 3e-26)"
                     /gene_kind="regulatory"
                     /note="unnamed protein product; orf2"
                     /protein_id="BBG06138.1"
                     /transl_table=11
                     /translation="MSEEKDGGAGKGSTLTRQGSIRRTSLLDAAEAVLVAKGSDASLRA
                     IAGEAGVRVGHLQHYFPTRADLIKAVLERALERSLERLAETTGLRMVRDDPSAIELPAG
                     PANPDEVVGVVLAEQDDPQLVRLYVEVWALAARDDEIATVVREFYRKYVAHVEAYVQQG
                     RPDWSGEFCRARAETFVALVEGAALMRSGIAGSRSSAMDAQLAQFAVQLLRD"
     CDS             1897..3075
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 409.5; E-value:
                     2.4e-124)"
                     /gene_kind="biosynthetic-additional"
                     /note="unnamed protein product; orf3"
                     /protein_id="BBG06139.1"
                     /sec_met_domain="p450 (E-value: 7.1e-32, bitscore: 100.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEVVDLAELASTAGLEQELGRLAKRHGIIRTRQLNGQETWTVLG
                     AALTRELLSDPRLSNDVHTHAPHGALVPGMAVMLLEQDDPDHARHRRLVSAAFASRAVR
                     QLEPRIAEITDQLLDKLGDRGTADFIEEFTYPMPLEVICELLGVPAEDRDPFRQWAMDI
                     SAAPSLEAMQSAAAELFGYCIGLIGAKRERPTEDLLSELIAARFEDGSALSDEELSSFA
                     AVLLIAGHDTVTNLLANALHDLLAHPEQLAALRADPSLVGAAVEEALRFRGSAMTTVNR
                     VALEDVEAGGVVIRKGELVRFLLNAANRDPEVREDPHAFDLGRATAQHLSFGVGPHFCL
                     GQRLARQEATIALTEILRRFGTLELAVPAEEVRWLPSDAIRGLVELPLRYER"
     CDS             3118..3312
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265:ferredoxin
                     (Score: 65.9; E-value: 4.6e-20)"
                     /gene_kind="other"
                     /note="unnamed protein product; orf4"
                     /protein_id="BBG06140.1"
                     /transl_table=11
                     /translation="MVEIRVDRDVCDGLGQCALVAPEVFALDDDERLVVAPEVPDGLAG
                     KVAAAVRACPVRALVVEGA"
     CDS             3316..4509
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175:pyridine nucleotide-disulfide oxidoreductase
                     (Score: 92.1; E-value: 4.7e-28)"
                     /gene_kind="biosynthetic-additional"
                     /note="unnamed protein product; orf5"
                     /protein_id="BBG06141.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5e-47, bitscore:
                     150.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREVVVVGAGLAGVRAAGSLRAEGFDGRLTVVSDERELPYDRPPL
                     TKQVVAGTMTGDDIRLAGEAEFGARWIRGTGAVGLDRERRRVRLADGAELPYDGVVLAP
                     GAKAREWPGAGVPDGVVTVRGLADVRRLRAEVAGGADEVVIVGAGFVGVELASSLSGLG
                     VKVTLVEPFGAPLRALGGTVAEVVSEAAGRAGVALRLGVGVRGFAAAAGGRVRAVVLAD
                     GAEVSASLVVVAIGMVPATGWLVGSGLALPSGRIHCDERLFARAAGGAGGAGVADPAVV
                     VAGDAAWCEAVRTAEGPVPLEHWSNAAAQGELAGRNLLAGPAAAEPYVHVPSFWTAAFG
                     LRIRSVGLPGTGDREVVEAGSAAEGAVLVAHYRGERLVGAVSVNQGKLLPGYARRLN"
     CDS             4658..4843
                     /codon_start=1
                     /note="unnamed protein product; orf6"
                     /protein_id="BBG06142.1"
                     /transl_table=11
                     /translation="MTLLGSSGNVFIAPPGEAVQVLSVGHDEVVSPTYYGLFLCKQVSG
                     GSFATGDGMCHAFSDV"
     gene            5201..5779
                     /gene="stmA"
     CDS             5201..5779
                     /NRPS_PKS="Domain: PP-binding (12-69). E-value: 1.9e-11.
                     Score: 36.3. Matches aSDomain:
                     nrpspksdomains_stmA_PP-binding.1"
                     /codon_start=1
                     /gene="stmA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /product="acyl carrier protein"
                     /protein_id="BBC20645.1"
                     /sec_met_domain="PP-binding (E-value: 5e-12, bitscore:
                     36.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNPYEADRIHDIVREGLAQVLGSSVDEITADATLVSDLGAESLD
                     LVEFRFEMETKLGVALPKSNVLDQLASALGGSEQLYDERGGISELAAEVLRRSAFGYSE
                     EQVHAGMRPYEVAAAATSAHWAAFTHRIFDHLPEACTECAADKAQIAPSGKVQCAGCGA
                     ALEAATGDEVMAEGVRAALAALGHAQPVG"
     aSDomain        5237..5407
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stmA_PP-binding.1"
                     /evalue="1.90E-11"
                     /label="stmA_PP-binding.1"
                     /locus_tag="stmA"
                     /protein_end="69"
                     /protein_start="12"
                     /score="36.3"
                     /tool="antismash"
                     /translation="IVREGLAQVLGSSVDEITADATLVSDLGAESLDLVEFRFEMETKL
                     GVALPKSNVLDQ"
     gene            5822..7132
                     /gene="stmB"
     CDS             5822..7132
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (62-435). E-value:
                     4.6e-46. Score: 149.4. Matches aSDomain:
                     nrpspksdomains_stmB_PKS_KS.1"
                     /codon_start=1
                     /gene="stmB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 316.8; E-value:
                     3.9e-96)"
                     /gene_kind="biosynthetic-additional"
                     /product="beta-ketoacyl synthase"
                     /protein_id="BBC20646.1"
                     /sec_met_domain="t2fas (E-value: 1.4e-95, bitscore: 310.4,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVNPHIPAGAGHEVVVTGIGLVAGRLTDPEALFDHLAQGNTLIA
                     EHPLHKEWGVPCAVSAHIDPAVRRSLEEAVPPEARPLGPAGALAWHAAAQAWERSGLPR
                     RLDSERGGVFLACNRMVMEPAELAGLADHVDFEAGALDLDAYLDAGGPDPRRHERVQPD
                     TATARLADYFGAAGVLETHADACAAGGMAIGSAYRYIRSGTLDVALAGGAESLTTLASV
                     AAFYGIGALAPAGDRDAAELSRPFDKDRSGFVIGDGAAFLVLESRAHAEARGARVLARV
                     AGYAGVTEAVKMTSSSRDGSDYATCIRAALADGGLTPDDIDHVNAHGTSTEANDTCEAA
                     ALHTVFGERVGRIPVTGNKSAMGHSLANSGAAEAVLSVLSLQRQAVLPTLNFHEPDEVT
                     RGLDIVTEQRHTPVTTVLSNSFGFGGQNCSLILAQAG"
     aSDomain        6008..7126
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stmB_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.60E-46"
                     /label="stmB_PKS_KS.1"
                     /locus_tag="stmB"
                     /protein_end="435"
                     /protein_start="62"
                     /score="149.4"
                     /tool="antismash"
                     /translation="IDPAVRRSLEEAVPPEARPLGPAGALAWHAAAQAWERSGLPRRLD
                     SERGGVFLACNRMVMEPAELAGLADHVDFEAGALDLDAYLDAGGPDPRRHERVQPDTAT
                     ARLADYFGAAGVLETHADACAAGGMAIGSAYRYIRSGTLDVALAGGAESLTTLASVAAF
                     YGIGALAPAGDRDAAELSRPFDKDRSGFVIGDGAAFLVLESRAHAEARGARVLARVAGY
                     AGVTEAVKMTSSSRDGSDYATCIRAALADGGLTPDDIDHVNAHGTSTEANDTCEAAALH
                     TVFGERVGRIPVTGNKSAMGHSLANSGAAEAVLSVLSLQRQAVLPTLNFHEPDEVTRGL
                     DIVTEQRHTPVTTVLSNSFGFGGQNCSLILAQA"
     gene            7141..8337
                     /gene="stmC"
     CDS             7141..8337
                     /codon_start=1
                     /gene="stmC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_kind="biosynthetic-additional"
                     /product="beta-ketoacyl synthase"
                     /protein_id="BBC20647.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.7e-10, bitscore:
                     30.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNLDAVRLTAPGLYTAAGADPASLWEALVAGKDTGRSDELLAEA
                     WPGAGTAFLVDDPDAATLGVHRRVLRTSEKQARMALYGARLALTGPSVTGPVGGEGWGL
                     YLGLPTVDEQLLRFSALDGLRRAADDSPGAVAALYGREVPPFSGLSHLNSTAAAHISAV
                     FGLTGAMAAYSPFSDAGLSALVDGVLSVAEGENEAAVIGAVSPKVHPLLFPQYEELGWT
                     GAAPGEGAAFLVARRGPDVPGARDVPAAPDGPAVRLAGYGRGFGADGADLTSALTEAVH
                     AALAMAGTDAAGIGWVLPDAGWTAAGEQAQRAALDRVFGPAGARPAVAGAERATGVLGP
                     AHPLAHVVLALHGLATGRLLADDGETVREEPLPVSRVLVLACGARGQVCAVVLEGAGS"
     gene            8334..9620
                     /gene="stmD"
     CDS             8334..9620
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (143-425). E-value:
                     3.4e-55. Score: 179.5. Matches aSDomain:
                     nrpspksdomains_stmD_PKS_KS.1"
                     /codon_start=1
                     /gene="stmD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 330.5; E-value:
                     2.7e-100)"
                     /gene_kind="biosynthetic-additional"
                     /product="beta-ketoacyl synthase"
                     /protein_id="BBC20648.1"
                     /sec_met_domain="t2fas (E-value: 2.6e-111, bitscore: 362.2,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRVVVTGLGAVCGLGLDWQTVWEGLCEGRSAIRGWQPPGVDDF
                     PVRYAAPVDDAAFAARYGADEDPGPVERRVRFGLAAAGQALADAGLAAGGDGAWTAGRI
                     GTAVGSGVPERDPLELLPALGEDGQPSWQALYARRDRLDRASGLFCTNDALAAGIAARH
                     RLRGPALNFSTACAGATHAIGHGFRMIRRGEVDAMVVGGADSVLNLPTMTGLHLLGAPS
                     TSELFGDRLCRAFDRDRSGLVAAEGAAMLVLESEESARRRGAIVYAEVAGFGSSLDAYQ
                     VTAPHPDGVGAALAMRRALADGGVAPEAVDSVNAHGTSTPLNDPIETRAIKDVFAGGEH
                     YRKLAVTANKTMLGHLIAAAGAPELIATVLSVRDGIVPPTLNLENPDPACDLDYVPDKA
                     RHQEVSVAVSNSFGFGGLNASLVVRGYDD"
     aSDomain        8763..9608
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stmD_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.40E-55"
                     /label="stmD_PKS_KS.1"
                     /locus_tag="stmD"
                     /protein_end="425"
                     /protein_start="143"
                     /score="179.5"
                     /tool="antismash"
                     /translation="RASGLFCTNDALAAGIAARHRLRGPALNFSTACAGATHAIGHGFR
                     MIRRGEVDAMVVGGADSVLNLPTMTGLHLLGAPSTSELFGDRLCRAFDRDRSGLVAAEG
                     AAMLVLESEESARRRGAIVYAEVAGFGSSLDAYQVTAPHPDGVGAALAMRRALADGGVA
                     PEAVDSVNAHGTSTPLNDPIETRAIKDVFAGGEHYRKLAVTANKTMLGHLIAAAGAPEL
                     IATVLSVRDGIVPPTLNLENPDPACDLDYVPDKARHQEVSVAVSNSFGFGGLNASLVVR
                     G"
     gene            9610..11001
                     /gene="stmE"
     CDS             9610..11001
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (202-422). E-value:
                     4.3e-19. Score: 60.5. Matches aSDomain:
                     nrpspksdomains_stmE_PKS_KS.1"
                     /codon_start=1
                     /gene="stmE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 148.2; E-value:
                     4.7e-45)"
                     /gene_kind="biosynthetic-additional"
                     /product="beta-ketoacyl synthase"
                     /protein_id="BBC20649.1"
                     /sec_met_domain="t2clf (E-value: 8.6e-37, bitscore: 116.7,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDLPSTNPSDELHDDPNPRTPHTPGTSGTGFDPDAIVVTGIGA
                     VLPTGRGPEALWSAWRQAQPALSPYRDPYVRTRKISHFGHVPDALQEESRDSVPHKLRK
                     FGTPFTFNAVLAAQDAMAAAGESWQQVPEERRGLYVAQDDSTDLSAAAFHKALDNARTD
                     HSPEAGVNLTRLVAEAFGNAATFNPFTVIRALNNNTLALISIAQRFRGDCAAFVQDAGA
                     ALGALQRAAFTLREGTCDTALVVGAGSYNEPLKLAAQYRAGHLTPGGPDGAALRSFDAE
                     RDGTVLAEGAVALVLERAGDAAARGARPLVTFLGAALRPAVDSGVGPSALAEGPRGLLA
                     EHGLTPDTLGAVLADGKGTVRHDAAEAELLRALLKDSGVLVGSLRPVTGTLGAAGPLAE
                     LALAPHLFATGELPPIAHLRTPPDDGTDFVMGAPRKRRIDSVLSLHSTFNGFAGALLAQ
                     RPHTD"
     aSDomain        10216..10875
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stmE_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="4.30E-19"
                     /label="stmE_PKS_KS.1"
                     /locus_tag="stmE"
                     /protein_end="422"
                     /protein_start="202"
                     /score="60.5"
                     /tool="antismash"
                     /translation="ISIAQRFRGDCAAFVQDAGAALGALQRAAFTLREGTCDTALVVGA
                     GSYNEPLKLAAQYRAGHLTPGGPDGAALRSFDAERDGTVLAEGAVALVLERAGDAAARG
                     ARPLVTFLGAALRPAVDSGVGPSALAEGPRGLLAEHGLTPDTLGAVLADGKGTVRHDAA
                     EAELLRALLKDSGVLVGSLRPVTGTLGAAGPLAELALAPHLFATGELPPIAHLRTPP"
     gene            11024..13909
                     /gene="stmF"
     CDS             11024..13909
                     /NRPS_PKS="Domain: Aminotran_3 (24-442). E-value: 2.7e-59.
                     Score: 192.7. Matches aSDomain:
                     nrpspksdomains_stmF_Aminotran_3.1"
                     /codon_start=1
                     /gene="stmF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 291.7;
                     E-value: 1.4e-88)"
                     /gene_kind="biosynthetic-additional"
                     /product="aminotransferase class III"
                     /protein_id="BBC20650.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.9e-58, bitscore:
                     187.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQFTEFVQPQMGRIFTALGLDVEYVRAEGNTLHHRDEQGAEVPV
                     LDLMGGYGSLILGHNHPEIVAHAHDLLDQRRAVHAQFSLREEAGRLGAALSDVVRRETS
                     VKEPYVATFGNSGAEAVEAAVKHAELVRVRAVAELADSVAAHVERAREAVGRGEAVVDA
                     DAFHAPAVRERAPEGEGIEALLAAVGAHNTAALATRPLFLALERSFHGKLVGSVQLTYN
                     SGFRTPFAHLGTRVRFVPMDRPELLDAIADEERVTLLDVETDGGRVRVVERDLPVITAF
                     LVEPVQGEGGIHALTVEQGRAIRLFCNKVGTALIIDEVQSGLGRCGAFLASSLIGLRGD
                     YYTLSKSLGGGLAKISAMLVRKSLYQGEFDIIHSSTFAMDDFSSGVARKVVELLEAGDG
                     QLYRQVTERGERLTAVLNDLKAAYPDVIEDVRGKGLFLGVQLRDQGGARSMVLRGSAYT
                     GSLGYLLSGYLLRQERIRIAPTGSAGNVLRIQPSAYLTDEEIEQVRGALDRLCRILRHE
                     DTLHLVHPASDRRIPKPRAEIRDFRGTLPGYEQDAPRPVTGPVRKVAFLNHLIEPAHLR
                     QVDPALADLSDAALRSFVLGMDPVKKAAPYPGVRIDSPLGSAVEFALYPLMVSSEQMGG
                     YLASGDVTGIRADIEERVQAARDDGCAVAGLGMYTSIVTNNCTSLRVPGIALTSGNALT
                     VAMGVQAMERGAQDRGWKVEDATLAVVGAAGNIASVYSQLFAERLGRIVLVGSRRDGSV
                     RRLRNTVHGIYQECWSRIAAGGELTGIPARLAEEPLITKWLAEGPGGDDAGRGRAIAEH
                     LQERYGSDPFLTVTQDSAALREAQLVLAASNSPEPFLTGEHFADGAVICDIAVPNNVVP
                     GVTEQRPDLAYMLGGIVATPNGESLHPSARAFLEAGQLFACMAETALMGLAGLDRHYSY
                     GNISRQQVIDIAALADAHGLRLADYKSAHSV"
     aSDomain        11096..12349
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stmF_Aminotran_3.1"
                     /evalue="2.70E-59"
                     /label="stmF_Aminotran_3.1"
                     /locus_tag="stmF"
                     /protein_end="442"
                     /protein_start="24"
                     /score="192.7"
                     /tool="antismash"
                     /translation="YVRAEGNTLHHRDEQGAEVPVLDLMGGYGSLILGHNHPEIVAHAH
                     DLLDQRRAVHAQFSLREEAGRLGAALSDVVRRETSVKEPYVATFGNSGAEAVEAAVKHA
                     ELVRVRAVAELADSVAAHVERAREAVGRGEAVVDADAFHAPAVRERAPEGEGIEALLAA
                     VGAHNTAALATRPLFLALERSFHGKLVGSVQLTYNSGFRTPFAHLGTRVRFVPMDRPEL
                     LDAIADEERVTLLDVETDGGRVRVVERDLPVITAFLVEPVQGEGGIHALTVEQGRAIRL
                     FCNKVGTALIIDEVQSGLGRCGAFLASSLIGLRGDYYTLSKSLGGGLAKISAMLVRKSL
                     YQGEFDIIHSSTFAMDDFSSGVARKVVELLEAGDGQLYRQVTERGERLTAVLNDLKAAY
                     PDVIEDVRGKGLFLGVQLR"
     gene            13942..14688
                     /gene="stmG"
     CDS             13942..14688
                     /NRPS_PKS="Domain: PKS_KR (6-168). E-value: 1.3e-21. Score:
                     69.2. Matches aSDomain: nrpspksdomains_stmG_PKS_KR.1"
                     /codon_start=1
                     /gene="stmG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     241.8; E-value: 1.3e-73)"
                     /gene_kind="biosynthetic-additional"
                     /product="enoyl-(acyl carrier protein) reductase"
                     /protein_id="BBC20651.1"
                     /sec_met_domain="adh_short (E-value: 3.1e-44, bitscore:
                     141.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.3e-35, bitscore:
                     113.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFEGQVALVTGGSRGIGRAIALKLAEGGCDIALNYRSATREAEQ
                     AAERIAALGRRIELFQGDVSDPDVPRQLVAGVRAAFGRIDVLVNNAGITRDELLVNQSL
                     KDIEQVLATNLVAPMLTVQAVAPLMMRQRYGRIVNISSSAASKPGRGQSNYAAAKGGLE
                     AFTKAMAVELASRGILVNAVAPGVINTEMTDAIRSHGEDEIMRRLLVKSYAEPETIADA
                     VAYLASPRNTYATGEVLHIDGGLKMA"
     aSDomain        13960..14445
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stmG_PKS_KR.1"
                     /evalue="1.30E-21"
                     /label="stmG_PKS_KR.1"
                     /locus_tag="stmG"
                     /protein_end="168"
                     /protein_start="6"
                     /score="69.2"
                     /tool="antismash"
                     /translation="VALVTGGSRGIGRAIALKLAEGGCDIALNYRSATREAEQAAERIA
                     ALGRRIELFQGDVSDPDVPRQLVAGVRAAFGRIDVLVNNAGITRDELLVNQSLKDIEQV
                     LATNLVAPMLTVQAVAPLMMRQRYGRIVNISSSAASKPGRGQSNYAAAKGGLEAFTKA"
     CDS_motif       13966..14109
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stmG_0001"
                     /evalue="1.70E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="stmG"
                     /protein_end="56"
                     /protein_start="8"
                     /score="20.6"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAIALKLAEGGCDIALNYRSATREAEQAAERIAAL
                     GRR"
     CDS_motif       14359..14415
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stmG_0002"
                     /evalue="5.30E-05"
                     /label="PKSI-KR_m4"
                     /locus_tag="stmG"
                     /protein_end="158"
                     /protein_start="139"
                     /score="15.7"
                     /tool="antismash"
                     /translation="ISSSAASKPGRGQSNYAAA"
     CDS_motif       14419..14472
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stmG_0003"
                     /evalue="7.20E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="stmG"
                     /protein_end="177"
                     /protein_start="159"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="GGLEAFTKAMAVELASRG"
     gene            14699..15529
                     /gene="stmH"
     CDS             14699..15529
                     /NRPS_PKS="Domain: PKS_KR (26-178). E-value: 1.8e-15.
                     Score: 49.1. Matches aSDomain:
                     nrpspksdomains_stmH_PKS_KR.1"
                     /codon_start=1
                     /gene="stmH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     218.7; E-value: 1.4e-66)"
                     /gene_kind="biosynthetic-additional"
                     /product="enoyl-(acyl carrier protein) reductase"
                     /protein_id="BBC20652.1"
                     /sec_met_domain="adh_short (E-value: 1.5e-36, bitscore:
                     116.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDVTTPGVPGVPGGGPAPGELAGKTAVVTGAAQGIGRETALLL
                     AEAGAARLILLDRDAGQLETVVKEAAGLGATAVAVAADLRDRELLRGRLRAELRAAGTL
                     DILVNNAGVADENGPDDETTWLRVLDINLHGTFAVTAACLEYLVDHGRIVNVSSILGKA
                     GKMRNTAYCASKHGLIGYTKGLALDLAARGITVNAVLPGWIDTPMLRRELAAQADEIGA
                     DPARMLRQARKGIPLRRLVEAREAAELIGFLVSGRAAAITAQSLTVDGGYTRGM"
     aSDomain        14777..15232
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stmH_PKS_KR.1"
                     /evalue="1.80E-15"
                     /label="stmH_PKS_KR.1"
                     /locus_tag="stmH"
                     /protein_end="178"
                     /protein_start="26"
                     /score="49.1"
                     /tool="antismash"
                     /translation="TAVVTGAAQGIGRETALLLAEAGAARLILLDRDAGQLETVVKEAA
                     GLGATAVAVAADLRDRELLRGRLRAELRAAGTLDILVNNAGVADENGPDDETTWLRVLD
                     INLHGTFAVTAACLEYLVDHGRIVNVSSILGKAGKMRNTAYCASKHGL"
     CDS_motif       14783..14872
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stmH_0001"
                     /evalue="1.30E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="stmH"
                     /protein_end="58"
                     /protein_start="28"
                     /score="30.6"
                     /tool="antismash"
                     /translation="VVTGAAQGIGRETALLLAEAGAARLILLDR"
     CDS_motif       15131..15271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stmH_0002"
                     /evalue="1.90E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="stmH"
                     /protein_end="191"
                     /protein_start="144"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="EYLVDHGRIVNVSSILGKAGKMRNTAYCASKHGLIGYTKGLALDL
                     AA"
     gene            15519..16415
                     /gene="stmI"
     CDS             15519..16415
                     /NRPS_PKS="Domain: Thioesterase (23-253). E-value: 1.4e-52.
                     Score: 171.2. Matches aSDomain:
                     nrpspksdomains_stmI_Thioesterase.1"
                     /codon_start=1
                     /gene="stmI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 237.5; E-value: 1.9e-72)"
                     /gene_kind="biosynthetic-additional"
                     /product="thioesterase"
                     /protein_id="BBC20653.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.5e-14, bitscore:
                     43.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MECSRWLRRLGPAPAADGAPPAARVVCFPHAGGGAAAFRPLAKAV
                     AAAAAEEGAGPYEVLAVRYPGRHDRLHEERLEDLRELAARAFRGLLPLTGRQPLVLLGH
                     SMGALIAYEVTRLLEGTGAGRPLRLVVSGAWAPSRVRGGTVHLRDDDGLIEEIRRTRGT
                     DPRVLDDRELLAMALPVVRSDYKAVETYRHRPGPPLDTPLTALVGDADPLVAVDDAAAW
                     RAHTAGDFRLRVFPGGDHFYLTRHWPDLARAVVAAPDRAASDRQGAVRPAGPGLLRGAQ
                     GGERQQAARPARLQQVG"
     aSDomain        15588..16277
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_stmI_Thioesterase.1"
                     /evalue="1.40E-52"
                     /label="stmI_Thioesterase.1"
                     /locus_tag="stmI"
                     /protein_end="253"
                     /protein_start="23"
                     /score="171.2"
                     /tool="antismash"
                     /translation="RVVCFPHAGGGAAAFRPLAKAVAAAAAEEGAGPYEVLAVRYPGRH
                     DRLHEERLEDLRELAARAFRGLLPLTGRQPLVLLGHSMGALIAYEVTRLLEGTGAGRPL
                     RLVVSGAWAPSRVRGGTVHLRDDDGLIEEIRRTRGTDPRVLDDRELLAMALPVVRSDYK
                     AVETYRHRPGPPLDTPLTALVGDADPLVAVDDAAAWRAHTAGDFRLRVFPGGDHFYLTR
                     HWPDLARA"
     CDS_motif       15807..15872
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_stmI_0001"
                     /evalue="9.40E-09"
                     /label="NRPS-te1"
                     /locus_tag="stmI"
                     /protein_end="118"
                     /protein_start="96"
                     /score="27.7"
                     /tool="antismash"
                     /translation="QPLVLLGHSMGALIAYEVTRLL"
ORIGIN
        1 cctggggccc tgggggcgtc gggtggatgc gtgacgggcg gccggcgggc ccggggtggg
       61 ggtgtgaggg caggtcgtgg gtctgggccg gccggtgtga cgtagatcgt cgttgtgttt
      121 ctaggtcgcg tgacctagtg tcggggttgt ggacgatgac atccagcttg atgtgacggg
      181 cccggttctt gtggtgggtg gctacgggac cgttggcggg gatttggcgc ggctggcggc
      241 tacttcgtgg ccgttgctcc tgacggggcg tacgccggag cgtggggcgg cgctggccga
      301 ggaggtcggt gcggcggtgc ggcggtggga tctgagtgat ccggagccgt tctcggcgaa
      361 ggtgcgggcc gtgatcagca cggtgaacga ccccgaggac cgggtgctgt tggcggcgat
      421 ccggggtggt gtgccgtatg tggacatcac acggtggacg gcgcggctgc agcgggcggt
      481 ggcggtggcg gcggtgaacc cgccgaaggc gccggtgctg ttgtcgtcga gctggatggg
      541 cggggtgacg gcgctggtcg cggccgcgct ggcggccgag gtcggcgggg cgtcggcggt
      601 ggagatcgcg atccggtacg acctgaagga ccgggcgggc acggactcgg tggagttcat
      661 ggaccggctg gggctggact acgaggtgac cgagggcggg cagcggcgga tgatcatgcc
      721 gttgtccggg gccggccatg tggccatcgg ggagcaccgg acgaaggtcg cgcggatcga
      781 cacgccggag cagttcacgc tgccgctggt gctgggggtg gacaccgccc tcacgcggat
      841 cgggttcagt gccaactcgt cgacgtcgac gctgctggcg ctgaagaaga ccgggttctt
      901 ccggtggggg cgtggtgaga agttccagtc gacgcggcgg tcgatgctgt attcgccggg
      961 tgagggcggc agtgcgtgcc tgcggatcga tgtgcgcggg cggggcggtc agcggcgtac
     1021 ggccgtgctg acggatccgg ccgggcaggc tcatctcacg gcgctgggcg ggctgttggg
     1081 gctgcgccgg gtgctgggcg aggacggggc ggccgcgccg cgcggggtgg tgttcccgga
     1141 gatgacgccg gtgccgcagg acgtcgtggc ggcgctggag aaggcgggcg tcggggtcga
     1201 ggtgtcatga gcgaggagaa ggacggcggg gccggtaagg gctcgacgct gacgcggcag
     1261 gggagcattc ggcggacgag tctgctggac gcggccgagg ccgtgctggt ggccaagggg
     1321 tcggatgcct cgttgcgggc gatcgccggt gaggcggggg tgcgggtcgg gcatctgcag
     1381 cactacttcc cgacccgggc ggatctgatc aaggccgtgc tggagcgggc gctggagcgt
     1441 tcgctggagc ggctggcgga gacgacgggg ctgcggatgg tgcgggacga cccgtcggcc
     1501 atcgagttgc cggcggggcc ggcgaacccc gacgaggtgg tgggggtggt cctcgccgag
     1561 caggacgatc cgcagctggt ccggctgtat gtcgaggtgt gggcgctggc ggcgcgggac
     1621 gacgagatcg ccaccgtggt gcgggagttc taccggaagt acgtggccca tgtggaggcg
     1681 tacgtccagc aggggcggcc ggactggtcg ggtgagttct gccgggcccg ggccgagacg
     1741 ttcgtggcgc tggtcgaggg ggcggccctg atgcggtcgg ggatcgccgg cagccggtcg
     1801 tccgcgatgg atgcgcaact ggcgcagttt gccgtgcaat tgctccggga ctgagcgttc
     1861 cggggccaac cagggggaat cagggggaag tacgtcatga ccgaagtggt ggatctggcc
     1921 gagctggcgt cgacggcggg gctggagcag gagctgggcc ggctggcgaa gcggcacggg
     1981 atcatccgta cccggcagtt gaacgggcag gagacctgga ccgtgctcgg ggcggcgctg
     2041 acgcgggagc tgttgagcga tccgcggctg tccaacgacg tgcacacgca tgcgccgcac
     2101 ggggcgctgg tgccggggat ggcggtgatg ctgctggagc aggacgaccc ggatcacgcg
     2161 cggcaccgcc ggctggtgag tgcggcgttc gcgtcgcggg cggtgcggca gttggagccg
     2221 cggatcgcgg agatcaccga ccagttgctg gacaagctgg gggaccgcgg tacggcggac
     2281 ttcatcgagg agttcacgta tccgatgccg ctggaggtga tctgcgagct gctgggggtg
     2341 ccggcggagg atcgggatcc gttccggcag tgggcgatgg acatctcggc ggcgccgtcg
     2401 ctggaggcga tgcagtcggc ggccgcggag ctgttcggat actgcatcgg gctgatcggg
     2461 gcgaagcggg agcggccgac ggaggatctg ctcagtgagc tgatcgcggc gcggttcgag
     2521 gacgggagtg cgctcagtga tgaggaactg tcgtcgttcg cggcggtgtt gctgatcgcg
     2581 gggcatgaca cggtcacgaa tctgctggcc aacgcgttgc acgatctgct ggcgcatccg
     2641 gagcagctgg cggcgctgcg ggcggatccg tcgctggtcg gtgcggcggt ggaggaggcg
     2701 ttgcggttcc gggggtcggc gatgacgacc gtgaaccggg tggcgctgga ggacgtcgag
     2761 gcgggcgggg tggtgatccg taagggggag ctggtgcggt tcctgctgaa cgcggcgaat
     2821 cgggatcccg aggtgcggga ggatccgcat gcgttcgacc tggggcgggc gaccgcgcag
     2881 catctgtcgt tcggggtggg gccgcacttc tgcctggggc agcggctggc ccgtcaggag
     2941 gcgacgatcg cgctgaccga gatcctgcgg cggttcggca cgctggagct ggcggtgccg
     3001 gcggaggagg tgcggtggct gccgtcggat gcgatccggg ggctggtgga gctgccgctg
     3061 cggtacgagc gctgacgcgg tatcaggagc agggtgagag cggtgggggg tagcgggatg
     3121 gtggagatcc gggtcgaccg ggacgtgtgt gacgggctcg ggcagtgtgc gctggtggcg
     3181 cccgaggtgt tcgcgctcga tgacgacgag cgcctggtgg tggcgccgga ggtgccggac
     3241 gggctggcgg gcaaggtggc cgccgcggtg cgggcgtgtc cggtgcgggc gctcgtggtc
     3301 gagggggcct gagcgttgcg cgaggtcgtc gtggtggggg cgggtctcgc gggggtgcgg
     3361 gccgcggggt cgctgcgggc cgaggggttc gacggccggc tgacggtggt gtcggacgag
     3421 cgggaactgc cctacgaccg gccgccgctg acgaagcagg tggtggccgg gacgatgacc
     3481 ggggacgaca tccggctggc gggtgaggcg gagttcggcg cccgctggat ccgggggacc
     3541 ggggcggtcg ggctggaccg ggagcggcgg cgggtgcggc tggccgacgg tgcggagctg
     3601 ccgtacgacg gggtggtgct ggcgccgggt gcgaaggcgc gggagtggcc cggggccggg
     3661 gtgccggacg gggtggtgac ggtgcggggg ctggcggacg tccggcggtt gcgggccgag
     3721 gtggccggtg gggccgatga ggtggtgatc gtcggtgccg ggttcgtcgg ggtggagctg
     3781 gcgtcgtcgc tgagcgggct gggggtgaag gtcacgctgg tggagccgtt cggtgcgccg
     3841 ctgcgggcgc tgggcggcac ggtggcggag gtggtgtcgg aggcggcggg ccgggcgggg
     3901 gtggcgttgc ggctgggcgt gggtgtgcgg ggtttcgcgg cggccgcggg cggccgggtg
     3961 cgggcggtgg tgctggcgga cggggcggag gtgtccgcgt cgctggtggt ggtggcgatc
     4021 gggatggtgc cggccacggg gtggctggtg gggtcggggc tggcgttgcc gtccgggcgg
     4081 atccactgtg acgagcggct gttcgcgcgg gccgcgggtg gtgccggtgg tgcgggtgtg
     4141 gcggatccgg cggtggtggt ggccggggac gcggcgtggt gtgaggcggt gcggacggcg
     4201 gaggggccgg ttccgttgga gcactggagc aatgcggccg cgcagggtga gctggcgggg
     4261 cggaatctgc tggcggggcc ggcggcggcc gagccgtatg tgcatgtgcc gtcgttctgg
     4321 acggcggcgt tcgggttgcg gatccggtcg gtggggctgc cgggtacggg ggaccgcgag
     4381 gtggtggagg cggggtccgc ggcggagggt gcggtgctgg tggcgcacta ccggggggag
     4441 cgtctggtgg gtgcggtgag tgtgaatcag gggaagctgc tgccggggta tgcgcggcgg
     4501 ttgaattagg cggccgggtc ggttttcggg acggttcggg acggaaaaac aggcccacgg
     4561 gtatgtgaat cccacgttaa gtttttcatt accacggaac cttttgagtt gaccccgcgg
     4621 ggaagagatt gggtcacgtg acctaccgca catttccgtg acgcttctgg ggagctctgg
     4681 taacgttttt atcgcgcctc cgggagaggc ggtgcaggtc ctttcggtgg gccacgacga
     4741 agtggtttcg ccgacgtatt acggcctgtt cctgtgtaag caggtatcgg ggggatcatt
     4801 tgctacgggg gatggcatgt gtcacgcgtt cagcgatgtc tgaagcgatg tctgaagcaa
     4861 tgtccgtaac gacgtcaggt ggccgggctt cccgcttccc gggagagtgc cccggcgttc
     4921 agcggcccgg ggccgagtgt gccgcgctgg cggccgccgc ctcctgccgg gcgtactgag
     4981 cagaattttc cgacggtttt ccggtaattc attccggctt tgcgaagccg ttctgtgtaa
     5041 aaccgtcgcg ggctcagtca tgtcctctca ccgcactttc cttccggttt tcgtccggtt
     5101 gacgaaacgt gccgccaagt aatttccgct gccgttttcc agtgtttcca tggccggtaa
     5161 aaggtggcgt gcagagtgct ttcgaaacga ggagagaacc atgcagaacc cctacgaggc
     5221 agaccggatc cacgacatcg tccgcgaggg actggcgcag gtgctgggca gcagcgtcga
     5281 tgagatcacc gcggacgcca ccctcgtctc cgacctcggg gccgaatccc tcgacctggt
     5341 cgaattccgc ttcgagatgg agaccaagct cggcgtggcg ctgcccaagt ccaatgtgct
     5401 cgaccagctg gcgtcggcgc tcggcgggtc ggagcagctc tacgacgagc gcggcgggat
     5461 ctccgagctg gccgccgagg tgctgcggcg cagcgcgttc ggctacagcg aggagcaggt
     5521 gcacgccggg atgcgcccgt acgaggtcgc cgcggcggcc accagcgcgc actgggcggc
     5581 gttcacccac cggatcttcg accaccttcc cgaggcctgc accgaatgcg ccgccgacaa
     5641 ggcgcagatc gcgccgtccg gcaaggtcca gtgcgccggc tgcggtgccg cgctggaggc
     5701 ggccaccggt gacgaggtga tggccgaggg cgtccgcgcg gcgctggccg cgctggggca
     5761 cgcccagccc gtcggctgac cctggccggc cgccgccgaa ggcgttcgac gtgcgaaagg
     5821 aatgcaagtg aacccccaca tacccgccgg ggccggtcat gaggtcgtgg tgaccggtat
     5881 cggcctggtg gccggtcgac tgaccgaccc cgaggcgctg ttcgaccatc tcgcgcaggg
     5941 gaacaccctc atcgccgagc acccgctcca caaggagtgg ggcgtgccct gcgccgtctc
     6001 ggcccacatc gaccccgcgg tgcggcggtc cctggaggag gcggtgccgc cggaggcccg
     6061 cccgctgggg ccggccggcg cgctcgcctg gcacgccgcc gcccaggcct gggagcgcag
     6121 cggactgccg cggcgcctgg actccgagcg cggcggcgtc ttcctcgcct gcaaccgcat
     6181 ggtgatggag cccgccgaac tcgccggtct ggccgaccat gtggacttcg aggcgggcgc
     6241 gctggacctg gacgcatacc tcgacgcggg cgggccggac ccgcggcggc acgagcgggt
     6301 ccagccggac accgccaccg cgcggctggc cgactacttc ggtgcggccg gggtgctgga
     6361 gacgcacgcg gacgcctgcg ccgcgggcgg gatggccatc ggcagcgcgt accgctacat
     6421 ccgcagcggc accctcgacg tggcgctggc cggcggcgcg gagagcctga cgacgctggc
     6481 ctcggtcgcc gcgttctacg ggatcggtgc gctggcgccg gccggggacc gggacgcggc
     6541 ggagctgagc cgcccgttcg acaaggaccg ctccgggttc gtcatcgggg acggcgccgc
     6601 gttcctggtg ctggagtcgc gggcgcacgc cgaggcccgg ggcgcccggg tgctggcccg
     6661 ggtcgcgggc tacgccgggg tgaccgaggc ggtgaagatg acgtccagtt cccgcgacgg
     6721 ctccgactac gccacctgta tccgggcggc gctcgcggac ggcgggctga ccccggacga
     6781 catcgaccac gtcaatgcgc acggcacctc gaccgaggcc aacgacacct gtgaggcggc
     6841 ggcgctgcac accgtgttcg gcgagcgggt gggccggatc ccggtgaccg gcaacaagtc
     6901 cgccatgggc cattcgctgg cgaacagcgg ggcggccgag gcggtgctgt cggtgctcag
     6961 cctgcagcgg caggccgtgc tgccgacgct caacttccac gagccggacg aggtgacccg
     7021 cggtctggac atcgtcaccg agcagcggca cacgccggtg accacggtgc tgtccaactc
     7081 cttcggtttc ggcgggcaga actgctcgct gatcctggcg caggcggggt gagtgacgcg
     7141 atgacgaacc tcgatgcggt gcggctgacc gcacccggct tatacaccgc ggcgggcgcg
     7201 gaccccgcgt cgctgtggga ggccctggtg gccggcaagg acaccggccg gtccgacgag
     7261 ctgctcgccg aggcctggcc cggcgcgggt accgcgttcc tcgtcgacga cccggacgcg
     7321 gcgacgctcg gtgtgcaccg gcgggtgctg cgcacctccg agaagcaggc gcggatggcg
     7381 ctgtacgggg cgcggctggc gctgaccggt ccctcggtga ccggcccggt gggcggggag
     7441 ggctggggtc tgtacctcgg actgcccacg gtcgacgagc agttgttgcg gttctccgcc
     7501 ctggacgggc tgcggcgggc ggcggacgac tcgcccggtg cggtcgcggc gctctacggc
     7561 cgggaggtcc cgccgttcag cgggctgtcc catctcaaca gcacggccgc ggcgcacatt
     7621 tcggcggtgt tcgggctgac cggtgcgatg gccgcgtact ccccgttctc cgacgcgggc
     7681 ctttcggccc tggtcgacgg ggtgctctcg gtcgccgagg gcgagaacga ggcggccgtc
     7741 atcggtgcgg tcagcccgaa ggtgcatccg ctgctgttcc cgcagtacga ggagctgggc
     7801 tggaccggtg ccgcccccgg ggagggggcc gcgttcctcg tcgcccggcg cgggccggac
     7861 gtaccggggg cgcgggacgt acccgcggcg cccgatggtc cggcggtgcg gctggccggt
     7921 tacgggcgcg ggttcggtgc ggacggtgcg gacctgacct cggcgctcac cgaggcggtg
     7981 cacgcggcgc tggcgatggc cggtaccgac gccgcgggga tcggctgggt gctgccggac
     8041 gccgggtgga cggcggccgg cgagcaggcc cagcgcgccg cgctcgaccg ggtcttcggg
     8101 ccggccggcg cccggcccgc ggtggccggg gccgagcgcg ccaccggtgt gctcgggccc
     8161 gcccatccgc tggcccatgt ggtgctggcg ctgcacgggc tggccaccgg gcggctcctc
     8221 gcggacgacg gggaaaccgt ccgcgaggag ccgctgccgg tctcccgggt gctggtgctg
     8281 gcctgcggcg cacgcggtca ggtgtgtgcc gtcgtactgg aaggagccgg atcatgagcc
     8341 gccgcgtcgt ggtgaccgga ctgggcgccg tctgcggact ggggctcgac tggcagaccg
     8401 tgtgggaggg cctgtgcgag ggccgctcgg cgatccgcgg ctggcagccg ccgggcgtgg
     8461 acgacttccc ggtgcgctat gcggcgccgg tcgacgacgc ggcgttcgcg gcgcggtacg
     8521 gggccgacga ggacccgggg ccggtggagc ggcgggtgcg gttcgggctg gcggcggccg
     8581 gccaggcgct ggccgacgcc ggtctggcgg ccggcgggga cggggcgtgg acggcgggcc
     8641 ggatcggcac cgcggtcggc tcgggcgtac cggaacgcga cccgctggag ctgctgccgg
     8701 ccctcggcga ggacgggcag cccagctggc aggcgctgta cgcgcggcgc gaccgactcg
     8761 accgggccag cggcctgttc tgcaccaatg acgcgctggc cgccgggatc gcggcccggc
     8821 accggctgcg cggcccggcg ctgaacttca gcaccgcctg cgcgggcgcc acgcacgcca
     8881 tcgggcacgg gttccggatg atccggcgcg gtgaggtgga cgcgatggtg gtgggcggcg
     8941 ccgactcggt gctgaacctg cccaccatga ccgggctgca cctgctgggg gcgccctcca
     9001 cgtccgagct gttcggggac cggctgtgcc gcgccttcga ccgggaccgc agcggtctgg
     9061 tcgccgcgga gggcgccgcg atgctggtgc tggagagcga ggagagcgcc cggcggcgcg
     9121 gcgcgatcgt ctatgccgag gtggcgggtt ttggtagctc cctcgacgct tatcaggtca
     9181 ccgccccgca tccggacggc gtgggcgcgg cgctggcgat gcgccgggcg ctggcggacg
     9241 gcggcgtggc tccggaggcg gtggactcgg tcaatgcgca cggcacgtcc acgcccctga
     9301 acgatccgat cgagacccgg gcgatcaagg acgtcttcgc cggcggcgag cactaccgga
     9361 agctggcggt gaccgccaac aagacgatgc tcgggcacct gatcgccgcg gccggcgcgc
     9421 cggagctgat cgcgacggtg ctgtccgtgc gcgacggcat cgtgccgccc acgctcaacc
     9481 tggagaaccc cgacccggcc tgcgatctcg attacgtccc ggacaaggcc cggcaccagg
     9541 aggtgtcggt ggcagtgagc aattccttcg gcttcggcgg cctcaacgcc agtctggtgg
     9601 tacgcggtta tgacgactga cctcccgagt acgaacccct cggacgagct ccacgacgac
     9661 cccaaccccc gcacccccca cacccccggc acctccggta cgggcttcga cccggacgcg
     9721 atcgtcgtca ccggcatcgg cgcggtgctg cccaccgggc gcggccccga ggcgctgtgg
     9781 tcggcctggc ggcaggcgca gccggcgctg tcgccgtacc gggacccgta cgtgcggacc
     9841 cggaagatca gccacttcgg acacgtgccg gacgcgctcc aggaggagag ccgggacagc
     9901 gtcccgcaca aactgcgcaa gttcgggacg ccgttcacgt tcaacgcggt gctcgccgcg
     9961 caggacgcga tggcggcggc cggggagagc tggcagcagg tgccggagga gcggcgcggg
    10021 ctgtacgtcg cgcaggacga ctccaccgac ctgagcgcgg cggcgttcca caaggcgctg
    10081 gacaacgccc gcacggacca ctcgccggag gcgggggtga acctgacgcg gctggtggcg
    10141 gaggcgttcg gcaacgcggc caccttcaac ccgttcaccg tcatccgggc gctgaacaac
    10201 aacacgctcg cgctgatcag catcgcgcag cggttccggg gcgactgcgc ggcgttcgtc
    10261 caggacgccg gggccgcgct gggcgcgctg cagcgggcgg ccttcacgct gcgcgagggg
    10321 acgtgcgaca ccgcgctggt ggtcggcgcc ggcagctaca acgagccgct gaagctggcc
    10381 gcgcagtacc gcgccggcca tctgacgccc ggcgggcccg acggggcggc gctgcgcagc
    10441 ttcgacgcgg agcgggacgg caccgttctg gccgagggcg cggtggcgct ggtgctggag
    10501 cgggccgggg acgcggcggc gcgcggggcg cggccgctgg tgacgttcct gggggcggcg
    10561 ctgcggccgg cggtggacag cggcgtcggc ccgtccgccc tcgccgaggg cccgcgcggg
    10621 ctgctggccg agcacggcct gacgcccgac accctcggcg ccgtcctcgc cgacggcaag
    10681 ggcaccgtcc ggcacgacgc cgcggaggcg gagctgctgc gggcgctgct gaaggacagc
    10741 ggggtgctgg tcggctcgct gcggccggtc accggcaccc tcggtgccgc cggcccgctg
    10801 gccgaactcg ccctggcgcc gcacctgttc gccaccgggg agctgccgcc gatcgcgcat
    10861 ctgcggacgc cgccggacga cggcaccgac ttcgtcatgg gtgcgcccag gaagcggcgg
    10921 atcgactccg tcctgagtct gcacagcacc ttcaacgggt tcgccggagc cctgctggcc
    10981 cagcggccgc acacggactg acgcacgagg ggaccaccaa cacatgtcgc agttcaccga
    11041 gttcgtgcag cctcagatgg gccggatctt caccgccctg gggctggacg tggagtacgt
    11101 ccgggcggag ggcaacaccc tccaccaccg tgacgagcag ggcgccgagg tgcccgtcct
    11161 ggacctgatg ggcggctacg gctcgctgat cctgggccac aaccatcccg agatcgtcgc
    11221 ccacgcgcac gatctgctcg accagcggcg ggccgtgcac gcccagttct cgctgcggga
    11281 ggaggccggc cggctcggcg ccgcgctcag cgacgtcgtc cggcgggaga cctccgtcaa
    11341 ggagccgtac gtcgccacgt tcggcaacag cggcgccgag gccgtcgagg cggccgtcaa
    11401 acacgccgag ctggtccggg tccgggccgt cgcggagctc gccgactccg tcgccgccca
    11461 tgtggagcgg gcgcgggagg cggtcggccg gggcgaggcc gtcgtcgacg cggacgcctt
    11521 ccacgccccg gcggtgcggg agcgggcgcc ggagggcgag ggcatcgagg cgctgctggc
    11581 ggcggtcggc gcgcacaaca cggcggcgct cgccacccgg ccgctgttcc tggcgctgga
    11641 gcggtccttc cacggcaagc tcgtcggcag cgtgcagctg acgtacaaca gcggcttccg
    11701 gacgccgttc gcccacctcg ggacgcgggt gcggttcgtg ccgatggacc ggcccgagct
    11761 gctggacgcc atcgccgacg aggagcgggt gacgctgctc gacgtggaga ccgacggcgg
    11821 gcgggtccgg gtcgtcgagc gggacctgcc ggtgatcacc gcgttcctgg tggagccggt
    11881 gcagggcgag ggcggcatcc atgcgctgac cgtcgaacag ggccgggcca tccggctgtt
    11941 ctgcaacaag gtcggcaccg cgctgatcat cgacgaggtg cagagcggcc tgggccgctg
    12001 cggcgcgttc ctcgccagct cgctgatcgg gctgcgcggc gactactaca cgctgtccaa
    12061 gtcgctcggc ggcggcctcg ccaagatctc cgcgatgctg gtgcggaagt cgctgtacca
    12121 gggcgagttc gacatcatcc acagttccac gttcgccatg gacgacttct cctcgggcgt
    12181 ggcccggaag gtcgtcgagc tgctggaggc cggcgacggg cagctctacc ggcaggtcac
    12241 cgagcgcggc gagcggctca ccgcggtgct gaacgatctc aaggccgcct accccgacgt
    12301 catcgaggac gtccgcggca agggcctgtt cctcggcgtg cagctgcgcg accagggcgg
    12361 ggcccgctcg atggtgctgc gcggcagcgc gtacaccggg tcgctgggct atctgctctc
    12421 cggctacctg ctgcggcagg aacgcatccg catcgcgccg accggcagcg ccggcaacgt
    12481 gctgcgcatc cagccgtccg cgtacctcac cgacgaggag atcgagcagg tgcgcggggc
    12541 gctggaccgg ctgtgccgca tcctgcgcca cgaggacacc ctgcacctgg tccacccggc
    12601 cagcgaccgc cggatcccca agccgcgcgc cgagatccgg gacttccggg gcacgctgcc
    12661 cggctacgag caggacgcgc cgcggccggt gaccgggccg gtgcgcaagg tcgcgttcct
    12721 caaccacctc atcgaaccgg cccatctgcg gcaggtcgac ccggcgctcg ccgacctgag
    12781 cgacgcggcg ctgcgctcgt tcgtcctggg catggacccg gtcaagaagg ccgcgcccta
    12841 ccccggcgta cggatcgact cgccgctcgg cagcgccgtg gagttcgcgc tctacccgct
    12901 gatggtgtcg tccgagcaga tgggcggcta tctggcctcc ggtgacgtga cggggatccg
    12961 cgcggacatc gaggagcggg tgcaggcggc ccgcgacgac ggctgcgcgg tggccggcct
    13021 gggcatgtac acctcgatcg tcacgaacaa ctgcacctcg ctgcgggtcc cgggcatcgc
    13081 gctgaccagc ggcaacgcgc tgaccgtggc gatgggtgtg caggcgatgg agcggggcgc
    13141 gcaggaccgc ggctggaagg tcgaggacgc cacgctggcc gtggtcggcg cggccggcaa
    13201 catcgcgtcg gtctacagcc agctgttcgc cgagcggctc ggccggatcg tgctggtcgg
    13261 cagccgccgc gacggctccg tccggcggct gcgcaacacc gtgcacggca tctaccagga
    13321 gtgctggtcg cggatcgcgg ccggcggcga actgaccggc atcccggcgc ggctcgcgga
    13381 ggagccgctg atcaccaagt ggctggccga ggggccgggc ggcgacgacg ccgggcgcgg
    13441 ccgggccatc gccgagcacc ttcaggagcg ctacggcagc gacccgttcc tgaccgtcac
    13501 ccaggacagc gcggcgctgc gcgaggcgca gctggtgctt gccgcctcca acagccccga
    13561 accgttcctg accggcgagc acttcgccga cggcgcggtg atctgcgaca tcgcggtgcc
    13621 caacaacgtg gtgccgggcg tgaccgagca gcggcccgac ctggcgtaca tgctcggcgg
    13681 gatcgtcgcc accccgaacg gcgagagcct gcacccgtcg gcgcgcgcct tcctggaggc
    13741 cggccagctg ttcgcctgca tggcggagac cgcgctgatg ggcctggcgg gcctggaccg
    13801 ccactactcg tacgggaaca tcagccgcca gcaggtcatc gacatcgcgg cgctggccga
    13861 cgcgcacggg ctgcggctgg ccgactacaa gagcgcccac tcggtctgag accggaccgc
    13921 accgactcgc gagaggacac catggaattc gaaggccagg tggcactggt gaccggcggc
    13981 agccggggca tcggccgggc catcgccctg aaactggcgg agggcggctg cgacatcgcg
    14041 ctcaactacc gcagcgccac ccgcgaggcg gaacaggccg ccgagcggat cgccgcgctc
    14101 ggccgccgca tcgagctctt ccagggggac gtctccgacc ccgacgtgcc gcggcaactg
    14161 gtcgcgggcg tacgcgccgc cttcgggcgg atcgacgtgc tggtcaacaa cgccggcatc
    14221 acccgcgacg aactgctggt caaccagagc ctgaaggaca tcgagcaggt gctggccacc
    14281 aacctcgtcg cgccgatgct caccgtccag gccgtggcgc ccctgatgat gcgccagcgc
    14341 tacggccgga tcgtcaacat ctcctcgtcg gcggcctcca agccgggccg cgggcagtcc
    14401 aactacgcgg cggccaaggg cggtctggag gcgttcacca aggcgatggc ggtggaactc
    14461 gcctcccgcg ggatcctggt caacgcggtc gcccccggcg tcatcaacac ggagatgacc
    14521 gacgccatcc gcagccacgg cgaggacgag atcatgcgcc ggctgctggt gaagtcctac
    14581 gccgaacccg agaccatcgc cgacgccgtg gcgtacctgg caagcccgcg caacacgtac
    14641 gcgacgggcg aggtgctcca catcgacggc ggcctgaaga tggcgtgagg ggacgaccat
    14701 gaccgatgac gtgacaacgc ccggggttcc gggcgtgccg ggcggcggtc ccgcgcccgg
    14761 cgaactggcc gggaagacgg ccgtggtgac cggcgcggcc cagggcatcg gccgggagac
    14821 ggccctgctg ctggcggagg ccggcgccgc ccggctgatc ctcctcgacc gggacgccgg
    14881 gcagctggag acggtcgtca aggaggccgc cggcctgggc gccaccgccg tggccgtcgc
    14941 cgcggacctg cgcgaccggg aactgctccg cggccggctc cgcgccgaac tgcgggccgc
    15001 cggcaccctc gacatcctcg tcaacaacgc cggcgtggcc gacgagaacg ggcccgacga
    15061 cgagaccacc tggctgcggg tgctggacat caacctgcac ggcaccttcg cggtcaccgc
    15121 ggcctgcctg gaatacctcg tcgaccacgg gcggatcgtc aacgtctcgt cgatcctcgg
    15181 caaggccggc aagatgcgga acaccgccta ctgcgcctcc aagcacggcc tgatcggcta
    15241 caccaagggc ctcgccctgg acctcgcggc ccgcggcatc acggtcaacg ccgtcctgcc
    15301 cggctggatc gacacgccca tgctgcgccg cgaactcgcc gcgcaggccg acgagatcgg
    15361 cgccgacccg gcccggatgc tgcgccaggc ccgcaagggc atcccgctgc gccggctggt
    15421 cgaggcgcgg gaggccgcgg agctgatcgg gttcctggtg tccggccggg cggcggcgat
    15481 caccgcgcag agcctgaccg tcgacggggg ctacacccgt ggaatgtagc cggtggctgc
    15541 gcagactggg cccggcgccg gccgcggacg gggcgccgcc ggccgcccgg gtggtgtgct
    15601 tcccgcacgc cggcggcggc gcggccgcgt tccggccgct cgccaaggcg gtggcggcgg
    15661 ccgccgccga ggagggggcc ggcccgtacg aggtgctggc ggtgcgctac ccgggccgcc
    15721 acgaccgcct ccacgaggag cgcctggagg acctgcgcga actggcggcc cgggccttcc
    15781 gcggactgct gccgctcacc ggccggcagc ccctggtcct gctcgggcac agcatgggcg
    15841 cgctgatcgc ctacgaggtg acccggctgc tggaggggac gggcgccggc cgcccgctgc
    15901 gactcgtcgt ctccggcgcc tgggcgccct cccgggtccg cggcggcacc gtccacctgc
    15961 gggacgacga cgggctgatc gaggagatcc gccgcacccg gggcaccgac ccccgggtgc
    16021 tggacgaccg ggaactgctg gccatggcgc tgcccgtggt ccgcagcgac tacaaggccg
    16081 tcgagaccta ccggcaccgg cccggaccgc cgctcgacac ccccctcacc gcgctggtcg
    16141 gggacgccga cccgctggtg gcggtggacg acgcggcggc ctggcgggcg cacaccgccg
    16201 gggacttccg gctgcgggtc ttcccgggcg gcgaccactt ctacctgacc cggcactggc
    16261 cggacctggc gcgggccgtc gtcgcggcac cggaccgggc ggcctcagac cggcagggag
    16321 cggtgcggcc agcgggcccg ggcctgctcc gcggagcgca gggtggcgag cgtcaacagg
    16381 ccgcgcgtcc ggcccgcctc cagcaggtcg ggtagcgcgg gcagcggcgc gagggccgcg
    16441 atgtcgtcca ggacgagggt gagtggtggg tcgagccgac cgtcggatga ccgttcggcc
    16501 atgcggcggc cgtgctcgac cacgtgcgag aggagtgcgg tgagcagggg catcgcaccc
    16561 gggtcggtac gcggatcctc gacgggctcg cctaccacgt agagcgttcc cccttcgtcg
    16621 atgaatgatt cgagaaggag cgaatccgcg cgcagcggat tgcaggcgtc ccggatgtgg
    16681 atcgacgaca gcgcggccag cgcccgcccg accaactcct tggccgcctc ccggcgttcg
    16741 gcgtgcgcgg tgagcaccga ctccagctca ccggcctgcc cggcggacgc ctgggcgctg
    16801 gtccgcagga tccgcaccgg ctcctgcgcg ccgcccgcgg cgtgcgccca gcggtgcagc
    16861 tgccggaacg gccggccgtc caccgcggcg gcgtgcagcc agcagcgcaa cagcgtctcc
    16921 gcggcgtccg cgagcgccga gtccagcgag ctggtggggc gtacgggggc cagcagggcg
    16981 gcggcgcggg cggccgcggt
//
