BGC0001918: JBIR-06 biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 32,523 nt. (total: 32,523 nt).
This entry is originally from NCBI GenBank LC375135.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001918
Short description JBIR-06 biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
LC375135.1
via
Compounds
  • JBIR-06
Species Streptomyces sp. [taxonomy]
References
Chemical products information
JBIR-06 Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BBD17739.1
 1 - 1365 (-) hypothetical protein
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    • BBD17740.1
    • smlA
    		 1443 - 1961 (-) sigma factor
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      • BBD17741.1
      • smlB
      		 2466 - 16226 (+) non-ribosomal peptide synthetase
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        • BBD17742.1
        • smlC
        		 16219 - 21171 (+) polyketide synthase
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          • BBD17743.1
          • smlD
          		 21243 - 22037 (+) thioesterase
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            • BBD17744.1
            • smlE
            		 22074 - 22718 (-) phosphopantetheinyl transferase
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              • BBD17745.1
              • smlF
              		 22723 - 24201 (-) AMP-ligase
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                • BBD17746.1
                • smlG
                		 24201 - 24446 (-) acyl carrier protein
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                  • BBD17747.1
                  • smlH
                  		 24646 - 25650 (+) epoxidase complex component
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                    • BBD17748.1
                    • smlI
                    		 25647 - 25937 (+) epoxidase complex component
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                      • BBD17749.1
                      • smlJ
                      		 25930 - 26679 (+) epoxidase complex component
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                        • BBD17750.1
                        • smlK
                        		 26676 - 27173 (+) epoxidase complex component
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                          • BBD17751.1
                          • smlL
                          		 27170 - 28264 (+) epoxidase complex component
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                            • BBD17752.1
                            • smlM
                            		 28336 - 29145 (+) tryptophan dioxygenase
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                              • BBD17753.1
                              • smlN
                              		 29138 - 29950 (+) kynurenine formamidase
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                                • BBD17754.1
                                • smlO
                                		 29964 - 31220 (+) kynureninase
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                                  • BBD17755.1
                                  • smlP
                                  		 31224 - 32000 (-) aminotranferase
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                                    • BBD17756.1
                                    		 32061 - 32504 (-) chitinase
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                                      Biosynthesis information

                                      Biosynthetic modules

                                      Name
                                      Unk01
                                      Type
                                      nrps-type1
                                      Genes
                                      smlB
                                      Substrates
                                      threonine (evidence: Structure-based inference, Homology, Heterologous expression)
                                      Integrated Monomers
                                      Domains
                                      adenylation
                                      Name
                                      Unk02
                                      Type
                                      nrps-type1
                                      Genes
                                      smlF
                                      Substrates
                                      anthanillic acid (evidence: Structure-based inference, Homology, Heterologous expression)
                                      Integrated Monomers
                                      Domains
                                      adenylation
                                      Annotation changelog

                                      Entry version: 2

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-09-15
                                      Added NRP substrate specificities
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 1

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2019-10-16
                                      Submitted
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      Detailed domain annotation
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