BGC0001918: JBIR-06 biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 32,523 nt. (total: 32,523 nt).
This entry is originally from NCBI GenBank LC375135.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0001918
Short description JBIR-06 biosynthetic gene cluster from Streptomyces sp.
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: LC375135.1
Compounds
  • JBIR-06
Species Streptomyces sp. [taxonomy]
References
Chemical products information
JBIR-06
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BBD17739.1
 1 - 1365 (-) hypothetical protein
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  • BBD17740.1
  • smlA
 1443 - 1961 (-) sigma factor
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  • BBD17741.1
  • smlB
 2466 - 16226 (+) non-ribosomal peptide synthetase
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  • BBD17742.1
  • smlC
 16219 - 21171 (+) polyketide synthase
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  • BBD17743.1
  • smlD
 21243 - 22037 (+) thioesterase
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  • BBD17744.1
  • smlE
 22074 - 22718 (-) phosphopantetheinyl transferase
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  • BBD17745.1
  • smlF
 22723 - 24201 (-) AMP-ligase
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  • BBD17746.1
  • smlG
 24201 - 24446 (-) acyl carrier protein
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  • BBD17747.1
  • smlH
 24646 - 25650 (+) epoxidase complex component
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  • BBD17748.1
  • smlI
 25647 - 25937 (+) epoxidase complex component
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  • BBD17749.1
  • smlJ
 25930 - 26679 (+) epoxidase complex component
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  • BBD17750.1
  • smlK
 26676 - 27173 (+) epoxidase complex component
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  • BBD17751.1
  • smlL
 27170 - 28264 (+) epoxidase complex component
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  • BBD17752.1
  • smlM
 28336 - 29145 (+) tryptophan dioxygenase
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  • BBD17753.1
  • smlN
 29138 - 29950 (+) kynurenine formamidase
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  • BBD17754.1
  • smlO
 29964 - 31220 (+) kynureninase
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  • BBD17755.1
  • smlP
 31224 - 32000 (-) aminotranferase
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  • BBD17756.1
 32061 - 32504 (-) chitinase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
smlB
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Homology
  • Heterologous expression
smlF
Module ?
Specificity: anthanillic acid
Evidence for specificity:
  • Structure-based inference
  • Homology
  • Heterologous expression
Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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