LOCUS       BGC0001922             37780 bp    DNA     linear   BCT 19-OCT-2018
DEFINITION  Streptomyces sp. SoC090715LN-16 DNA, Isoindolinomycin biosynthetic
            gene cluster, complete sequence.
ACCESSION   BGC0001922
VERSION     BGC0001922
KEYWORDS    .
SOURCE      Streptomyces sp. SoC090715LN-16
  ORGANISM  Streptomyces sp. SoC090715LN-16
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Thong,W.L., Shin-Ya,K., Nishiyama,M. and Kuzuyama,T.
  TITLE     Discovery of an Antibacterial Isoindolinone-Containing Tetracyclic
            Polyketide by Cryptic Gene Activation and Characterization of Its
            Biosynthetic Gene Cluster
  JOURNAL   ACS Chem. Biol. 13 (9), 2615-2622 (2018)
   PUBMED   30080389
  REMARK    DOI:10.1021/acschembio.8b00553
REFERENCE   2  (bases 1 to 37780)
  AUTHORS   Kuzuyama,T. and Thong,W.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAY-2018) Contact:Tomohisa Kuzuyama The University of
            Tokyo, Biotechnology Research Center; 1-1-1 Yayoi, Bunkyo-ku, Tokyo
            113-8657, Japan URL
            :http://park.itc.u-tokyo.ac.jp/biotec-res-ctr/saiboukinou/
            index-e.html
COMMENT     ##antiSMASH-Data-START##
            Version  :: 8.dev-5707d64f
            Run date :: 2025-08-15 20:33:20
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     region          1..37780
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..333
                     /gene="idmB1"
     CDS             1..333
                     /codon_start=1
                     /gene="idmB1"
                     /product="hypothetical protein"
                     /protein_id="BBE36449.1"
                     /transl_table=11
                     /translation="MYGLWWRLNHWVRCVITALVRGLAAMGRLHVGGEECDPFPFRTGR
                     LSAPPARHPERLRPDLPPTALERSLEHVVRGFPWSGRTRHSGRTRHSGAQRLRGRPPSP
                     PGGPAG"
     source          1..37780
                     /db_xref="taxon:1898658"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. SoC090715LN-16"
                     /strain="SoC090715LN-16"
     misc_feature    1..37780
                     /note="Isoindolinomycin biosynthetic gene cluster"
     subregion       1..37780
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001922"
                     /subregion_number="1"
                     /tool="antismash"
     cand_cluster    1..37780
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..37780
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[16717:19206](-)"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      complement(16718..19206)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     gene            519..1943
                     /gene="idmB2"
     CDS             519..1943
                     /codon_start=1
                     /gene="idmB2"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /product="transporter"
                     /protein_id="BBE36450.1"
                     /transl_table=11
                     /translation="MEMKGAKFALGGRSSFRTPAPAKTDWWPLTAIGLAVFMLMLDATV
                     VTVALPDMAKDLHADLTDLQWVMNAYTLAMSGLQLTSGSLADRLGRRRLFLVGVALFAV
                     ASLACGLATTAAVLIGARIVQGLAGALMFATTLALIGQCYTGRNRGVAFGVRGTIAGVA
                     VVLGPLLGGALIAWLNWRWIFLVNLPVAVVTLALGWAKLPRRELLEKRRRMDVGGPVTL
                     AATLTLLMFALLRGTEDGWSSTRIMLLFSGAAVSFVAFLLVERAHRDPMLDLSLFRIPS
                     FTGTQIGSFAVQGSIFALFVYLSLYFQSVLGYSAMRAGLCFLAVVVPILIAGPLVGQFM
                     DKLPRRLLVTGSLLLLGTGLVVMHGITPASDWKDVAPGMAMAGFACGIALPTLGSLAVE
                     VADERRLGMASGVNNTVLQIGFAMGIAVYGAVLARYGTTRTDFIDGLNQLFLLAAAVAY
                     GGALITFLLIRPRPRR"
     gene            2006..3085
                     /gene="idmB3"
     CDS             2006..3085
                     /NRPS_PKS="Domain: Aminotran_1_2 (40-341). E-value:
                     2.2e-41. Score: 134.1. Matches aSDomain:
                     nrpspksdomains_idmB3_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="idmB3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /product="aminotransferase"
                     /protein_id="BBE36451.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-41, bitscore:
                     134.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRATPRLRPIVKYLASRDALHDGWTGGLPVDHRAHLNESPYPPL
                     PSVVATIRGTADQVNRYPDTGNTELAAAIADRLGVPAAHVTVGPGSTALIHQLFLAAVA
                     PRETVVLTDPCADRYAFLTLLSGARPVQVRLDRGRQDLASMLHAVNRRTRVVVVGNPHD
                     PTGTLVAGEHLTELLAALPSDILVVLDETYREFVGTRTTPDGVEAYRLWPNVVAVRSFS
                     AAHGLAGLRVGFALAQPALSTALRSTALPYGTTRLAELAALASLRATAEMSGRIHRLTG
                     ERDRLRSVLRAQGWTIPHSQANFLWLPLGTRSVAFARACGDQGIAVRVWEGRGVRVTIG
                     DPESNDLIAYVASRFPPAS"
     aSDomain        2126..3028
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB3_Aminotran_1_2.1"
                     /evalue="2.20E-41"
                     /label="idmB3_Aminotran_1_2.1"
                     /locus_tag="idmB3"
                     /protein_end="341"
                     /protein_start="40"
                     /score="134.1"
                     /tool="antismash"
                     /translation="PYPPLPSVVATIRGTADQVNRYPDTGNTELAAAIADRLGVPAAHV
                     TVGPGSTALIHQLFLAAVAPRETVVLTDPCADRYAFLTLLSGARPVQVRLDRGRQDLAS
                     MLHAVNRRTRVVVVGNPHDPTGTLVAGEHLTELLAALPSDILVVLDETYREFVGTRTTP
                     DGVEAYRLWPNVVAVRSFSAAHGLAGLRVGFALAQPALSTALRSTALPYGTTRLAELAA
                     LASLRATAEMSGRIHRLTGERDRLRSVLRAQGWTIPHSQANFLWLPLGTRSVAFARACG
                     DQGIAVRVWEGRGVRVTIGD"
     misc_feature    2237..2239
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3103..4119)
                     /gene="idmB4"
     CDS             complement(3103..4119)
                     /codon_start=1
                     /gene="idmB4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     C13O|C17O (Score: 451.1; E-value: 4.6e-138)"
                     /gene_kind="biosynthetic-additional"
                     /product="methyltransferase"
                     /protein_id="BBE36452.1"
                     /transl_table=11
                     /translation="MESTDSPEVGLQQLLDTATGFWRSQVLFSAVECGVFGALVDGPAT
                     LAELQERTGLHERAARDLLDSLGALGLLLREGDHYRNAPVTERHLDPKQPGYVGGFLMF
                     MSKSLYPAWGRLPELLRTGHLQEGDDSFGEFYRDPDRVRGFMSAMDSAAAAVTAELVKW
                     PDWQRYQNFVDLGGARGNLAGRIALAHPHLKGGCFDLPPLEPFFTEHMASLDTADRVVF
                     HGGDFRSDPLPEADVLLFGHVLHDWDEDTRRLLVARAHAALRPGGSLLVYDELIDDDRG
                     GPARSLLMSLNMKLVRSGASEYSAAEAREWLAEAGFTEVGVQELTATERLIVARKAD"
     gene            4227..5009
                     /gene="idmB5"
     CDS             4227..5009
                     /NRPS_PKS="Domain: PKS_KR (22-191). E-value: 8e-08. Score:
                     24.3. Matches aSDomain: nrpspksdomains_idmB5_PKS_KR.1"
                     /codon_start=1
                     /gene="idmB5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     129.4; E-value: 4.4e-40)"
                     /gene_kind="biosynthetic-additional"
                     /product="dehydrogenase"
                     /protein_id="BBE36453.1"
                     /transl_table=11
                     /translation="MVSRSALPSGRAGPENSGMTISLVTGANKGIGFQIARGIGGTVLV
                     GARDDTRGRAAETALREAGADAHHLRLDVTDQDTIDAAVKWVADTYGSLDVLVNNAGCP
                     ALDWDVPPSEVSLDAVRRTYDTNVVGVIAVTNAFLPLLREAPAARIVNVSSRLASLTLG
                     ADENSPVSRVNLLAYNSSKAALNSITQAYAKELRETPVKVNAVNPGFCATDMAAGMARY
                     GKGMRTAEEGARPVIAAALLTADGPTGAFFDESGPLPW"
     aSDomain        4293..4799
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB5_PKS_KR.1"
                     /evalue="8.00E-08"
                     /label="idmB5_PKS_KR.1"
                     /locus_tag="idmB5"
                     /protein_end="191"
                     /protein_start="22"
                     /score="24.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="LVTGANKGIGFQIARGIGGTVLVGARDDTRGRAAETALREAGADA
                     HHLRLDVTDQDTIDAAVKWVADTYGSLDVLVNNAGCPALDWDVPPSEVSLDAVRRTYDT
                     NVVGVIAVTNAFLPLLREAPAARIVNVSSRLASLTLGADENSPVSRVNLLAYNSSKAAL
                     NSITQA"
     gene            complement(5059..5790)
                     /gene="idmB6"
     CDS             complement(5059..5790)
                     /codon_start=1
                     /gene="idmB6"
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /product="regulatory protein"
                     /protein_id="BBE36454.1"
                     /transl_table=11
                     /translation="MTERSRRAKLRIRPNPDGLWSDEPMDQQRLDRAEIVRVALELLES
                     QGVDAFSMRGLATALNIKSPSLYWHVRSKDELYDLVVDAVLGECDMPEDDAEGDWRTQL
                     AEIAREMRRVLLLHPAATRLLTGRVPLGPNWLRIAESVIGTLRRAHFGDRLAGYCYLVL
                     LYYAIGFVSQEVAFGQGAEGRVRLDQMREFFAGLPGDRYPNVTAVAGGLAERGLSDRFE
                     LGLNGILGGFSEELAAEHGDA"
     gene            complement(5868..7226)
                     /gene="idmB7"
     CDS             complement(5868..7226)
                     /codon_start=1
                     /gene="idmB7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /product="oxidase"
                     /protein_id="BBE36455.1"
                     /transl_table=11
                     /translation="MPCALPGDPGYETARAVWNTDVRRAPLAVVRPVTVAGVRGAVRFA
                     ADRGLPVAVRGGGHSLAGFGTADDAVVLDLGALAGIDIDARGRTLTVGGGAVWGRVDEA
                     TQRAGLAVTGADVPSVGVGGTTVGGGFGWLHRAAGMTCDNLLSAEVLTAAGETLTAAPD
                     SHSDLYWALRGGGGNYGVVTAFRFRLRPVATVVSGTVLHAYDRAADVLLHYQDVCDRAP
                     DHLALRATLLTAPPAPFVPPELRGGPVVMIGVADFAPSPASERLITELRGFGTPAVADV
                     RPRPYLELQQPPGRTVEAMRAHGHSAFLGRLDERLVKVLVETAGQPPSPLAMIQLQLLG
                     GVAGRVPADATPVPLRDAVQLLGVNALAARQNRTAGLAGWTKAAADAVRPYVRGGPYVN
                     FVTGDETAEQIRTAYGADTYDRLAAVKGVHDPENVFRFNANIVPRPLRPPNPN"
     gene            complement(7265..8671)
                     /gene="idmB8"
     CDS             complement(7265..8671)
                     /codon_start=1
                     /gene="idmB8"
                     /product="dTDP-2,3-dehydratase"
                     /protein_id="BBE36456.1"
                     /transl_table=11
                     /translation="MPEVRGTLREGMALRLAESEAVTDSRLMPNHRFPQWFAERSAAHD
                     HAVRRVPFATLKGWRFDPGTGNLGHDSGRFFTVEGLRVRTDDPRHGSWRQPILNQPEIG
                     ILGIVVREFEGVLHCLMQAKMEPGNINLVQLSPTVQATRSNYTMVHGGRRPRHLEFFTG
                     DRPVAVVADSLQSEHGHYFLRKRNRNMIVEVMDGPPEHEDFCWLTVGQLLRLLHQDNLV
                     NMDARTVLSCLALADPAPGQDRAVRLLNWMTEMRTRHELVQTVVPLHDVPSWRRSADTV
                     GRPDGRGFSIVAVEVAAASREVAGWSQPLLRVGARSLAALAVRRGVDGELLLLVHARQE
                     PGLTDVVELGPTVQCVPDHERGLPPEQATRYLDRVLAMPAERVRCDVVHSEEGGRFDQA
                     ETRYLVVEAPDGFDEPLPDDYRWAPLDEVTALLRHSYCVNVQLRTLLLTLRNGLWPELH
                     ADRDLHRRNP"
     gene            complement(8774..9847)
                     /gene="idmB9"
     CDS             complement(8774..9847)
                     /codon_start=1
                     /gene="idmB9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-1-glucose synthase"
                     /protein_id="BBE36457.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.6e-16, bitscore:
                     51.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRRLRALVLAGGRGTRLRPFTPALPKQLMPVAGKPVLVRCLEQ
                     LPALGVSEAAVIVGDGRPQIEAVLGDGSGLGLSVTYVPQPEPLGLAHCVALARAFLGDD
                     SFVLCLGDVVVTDGLAAAHERFVCEGPDAVVLTAKVADPRQYGVVEVDGRGRVLALAEK
                     PRVPRSDLVLAGVYFLSPAVHKAVAGLRPSARGELEITDALSALVADGATVLSTPVTGY
                     WKDVGDVEAVLDCNRVLMEALAPERAGSVDAASRLDGTVVVESGASVLRSRLIGPVLVG
                     AGSVVRDSRVGPYTAIGRDCRVSDTEITGSVLLDGAVMAGLDGVHNSVIGRGAEVRATH
                     PRTDRCFLVGDHTYVEV"
     gene            complement(9844..10680)
                     /gene="idmB10"
     CDS             complement(9844..10680)
                     /codon_start=1
                     /gene="idmB10"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /product="monooxygenase"
                     /protein_id="BBE36458.1"
                     /transl_table=11
                     /translation="MRIGIGLPATLPGVQRTQLLEWARRAEARGFSTLAAFDRLVYDNL
                     EPLIALSAAAAVTTRIRLATTILIAPLRANPVLLAKQAASLNRLADGRLTLGLAPGGRQ
                     DDFTTSDLDFHTRGHTLDHHLTRLHDTWNNPDIGPHHTTPRLLIGGFTPTSFTRAATHA
                     DGWIAGGGDPDFFRHCAQQAHTAWHTAHRTDTPHLTATCYFGLGPDAEPRAGDYLRDYY
                     SFAGSLADRIAAGVLTTKKKVSAAVEEWRAAGADELILFPVDPDPRQVDLLADAVG"
     gene            complement(10701..12056)
                     /gene="idmB11"
     CDS             complement(10701..12056)
                     /codon_start=1
                     /gene="idmB11"
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /product="Na:H Exchanger"
                     /protein_id="BBE36459.1"
                     /transl_table=11
                     /translation="MSSLTMTSLTATAVVPPLDAHTTVVLLCNLGGLLAVAVLLGRLAA
                     HFHMPPVVGELCAGVLLGPSLLAHLAPGLSAWLLPPDPARMHLLDAVGQLGVLLLTGMT
                     GMQLDLGLVRRRGASAARISLFGIVLPLGLGVGAGFLVPGSLLPDTADRGTFAAFLGVA
                     MGVSAIPVIAKTLTEMRLLHRDVGQLTLCAVAIDDIIGWILLSAVSAMATSTLTAHSLL
                     AHLAWVPVVLLAALLLRPPIRALLRAVTRSGTPGLFLATVTVLLLLAAAGTQAAGLEGV
                     FGAFLCGVVIGSTGFATPERCAALTTVVLAVLAPLYFATAGLRVDLTALRRPAVLLTAV
                     VVLSLAVFGKFAGAYLGARLSRMGHWEGLALGAGMNARGVIEVIVAMVGLRLGVLSPAL
                     YTIVVLVAVITSLMAPPVLRVAMAKVEHTAEERLREHAAVADLSPAPSTEHR"
     gene            complement(12053..12814)
                     /gene="idmB12"
     CDS             complement(12053..12814)
                     /NRPS_PKS="Domain: Thioesterase (24-242). E-value: 4.2e-30.
                     Score: 97.8. Matches aSDomain:
                     nrpspksdomains_idmB12_Thioesterase.1"
                     /codon_start=1
                     /gene="idmB12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /product="thioesterase"
                     /protein_id="BBE36460.1"
                     /sec_met_domain="Thioesterase (E-value: 1.8e-26, bitscore:
                     85.0, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.1e-11, bitscore:
                     35.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATAAALDRWFLGPPPGPDAEAVLYCLPPAGAGATGYLGWRRHA
                     PAGLHVQPVQPPGRENRITEPPDLSTDELAEALCRRTDRPYALYGHSMGGVVAHAVVQA
                     LVRSGAPLPSRVYVGAAPPPLSPMSWLGRWLDAGDSDLVRETAALGGTPARVLAHARTR
                     ERLVRVLRSDLGWLAAHRPAVQPPLPVPLRGFAGDRDPLVGLDAMTGWRSFTDRSYVLR
                     AVRGGHFFHLEDPRTLARAVAADLRLTEEDL"
     aSDomain        complement(12089..12742)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB12_Thioesterase.1"
                     /evalue="4.20E-30"
                     /label="idmB12_Thioesterase.1"
                     /locus_tag="idmB12"
                     /protein_end="242"
                     /protein_start="24"
                     /score="97.8"
                     /tool="antismash"
                     /translation="LYCLPPAGAGATGYLGWRRHAPAGLHVQPVQPPGRENRITEPPDL
                     STDELAEALCRRTDRPYALYGHSMGGVVAHAVVQALVRSGAPLPSRVYVGAAPPPLSPM
                     SWLGRWLDAGDSDLVRETAALGGTPARVLAHARTRERLVRVLRSDLGWLAAHRPAVQPP
                     LPVPLRGFAGDRDPLVGLDAMTGWRSFTDRSYVLRAVRGGHFFHLEDPRTLARAV"
     CDS_motif       complement(12500..12568)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_idmB12_0001"
                     /evalue="4.70E-10"
                     /label="NRPS-te1"
                     /locus_tag="idmB12"
                     /protein_end="105"
                     /protein_start="82"
                     /score="31.8"
                     /tool="antismash"
                     /translation="DRPYALYGHSMGGVVAHAVVQAL"
     gene            complement(12819..14168)
                     /gene="idmB13"
     CDS             complement(12819..14168)
                     /codon_start=1
                     /gene="idmB13"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /product="pyruvate carboxylase"
                     /protein_id="BBE36461.1"
                     /sec_met_domain="ATP-grasp (E-value: 2.4e-12, bitscore:
                     38.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1e-13, bitscore:
                     42.6, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRKILVANRGEIAVRVVRACRELGIPSVAVHSTADADAEHVRLA
                     DESVHIGPAPARRSYLHIPNVVSAALRAGADAIHPGYGFLSEDPYFAEICASNGITFIG
                     PPPDVMDAVGDKASARRLMTEAGLPLLPGTAEAVAGPEEALAVAGELGYPVVVKALAGG
                     GGRGIAVARSAAELAHVYLTTRAHAQAVFGDSRVYVERFLPVARHIEIQVLADAHGNAV
                     HLGERDCSVQRRHQKLIEESPSPALDDQLRGQIGEAALLGTKALGYCGAGTMEFLLDDD
                     GRFWFMEMNARIQVEHPVTEMVCGVDLVQQQILVAAGAPLELEQADVNLRGHAVEVRIN
                     AEDPDRQFAPTPGTLTEFRLPAGPGVRVDTHCVPGSSIPAHYDSLIAKLVVWAQDRPAA
                     LNRMRRALGEVRVEGAGVRTTVPFHQRVLDHPVFRSGDAHTDFLTRHLEV"
     gene            complement(14176..14637)
                     /gene="idmB14"
     CDS             complement(14176..14637)
                     /codon_start=1
                     /gene="idmB14"
                     /product="biotin carboxyl carrier"
                     /protein_id="BBE36462.1"
                     /transl_table=11
                     /translation="MGEIDAPGESTRVQELSTAVERIVEGLPGTIRRLTVSVGECSVDV
                     TWSNRGARTAAPVAARPASTDVVGSAPALAVTAPLVGAFYSRPTPDAPAFVEIGAVVRP
                     GDQVALIEAMKLFTPVRTELAGRVIAFLVADGDMVEYGQPLLDLEPVEE"
     gene            complement(14624..16339)
                     /gene="idmB15"
     CDS             complement(14624..16339)
                     /codon_start=1
                     /gene="idmB15"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /product="acetyl-CoA carboxylase"
                     /protein_id="BBE36463.1"
                     /transl_table=11
                     /translation="MASPPLATDDWVRCTGCGELVYRRRLDRLLKVCPDCGHHFRLRAR
                     EWLDLLVDSGSGVRFGEEVVPEDVLGFVDSKPYPERIAEGRRRSGNSAAALCATARIDG
                     VPIVIAALDFAFLGGSIGGAVGELISRAARHALKDRVPLLIVSASGGARMQEGAIALMQ
                     LAKTSQEMARLHAAGVLVVNLNTDPTYGGASASFAMLGDVIIAEPGARIGFAGPEVIRQ
                     TIRQELPDRFQTAEFLWENGQIDLVVPREELRTVLSRLLRLHSLAARPGLRPVVSGDTA
                     HAGDTPVTDPALLPERDPAEIVALARDLGRPTTRDYCAYVFDDFLELHGDRQGGDDPAI
                     VGGLARLDGRTVVAIGHQKGHEVGELVRRNFGMPQPWGYHKAHRLMDYAARFGLPLVTF
                     VDTPGAYPGIEAEQRGQAYAIARCIMRMSELPVPVVCVVTGEGGSGGALALAVGNRVLI
                     LENSYFSVISPEGCSTILFGDRSAAQRAAEQLRLTPRDLLRLGIVDGVLKEPGDGAHTQ
                     HTATAQRVKAALVQTLDELSELQPSQLVDQRYQRYARFGDPKLRLTKGLGHGGD"
     gene            complement(16341..16661)
                     /gene="idmB16"
     CDS             complement(16341..16661)
                     /codon_start=1
                     /gene="idmB16"
                     /product="monooxygenase"
                     /protein_id="BBE36464.1"
                     /transl_table=11
                     /translation="MAVITGQDDYYTLVNVFKVAPEHQTRVYDAIVGATDVIRALPGFV
                     SANVHLTKDGVHVVNYAQWRSKADFDAMLVSPGVQDHFKVCRELAEMDTILCRTTALVE
                     AA"
     gene            complement(16718..17944)
                     /gene="idmB17"
     CDS             complement(16718..17944)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (53-406). E-value:
                     8.4e-34. Score: 109.1. Matches aSDomain:
                     nrpspksdomains_idmB17_PKS_KS.1"
                     /codon_start=1
                     /gene="idmB17"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ene_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) CLF
                     (Score: 630.4; E-value: 2.7e-192)"
                     /gene_kind="biosynthetic"
                     /product="beta-ketoacyl synthase"
                     /protein_id="BBE36465.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-47, bitscore:
                     153.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="t2clf (E-value: 1.7e-190, bitscore: 624.2,
                     seeds: 26, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 3.4e-32, bitscore: 103.1,
                     seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 1.2e-30, bitscore: 97.9,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 1.2e-24, bitscore: 78.2,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 7.7e-28, bitscore: 88.8,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 1.2e-19, bitscore: 61.5,
                     seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDATRVVITGIGALAANGDNAERHWAATLAGRSGIVPIGRFDAS
                     RYPTRLGGEIRGFDARGRVPRRLLPQTDRVTQYALAAAEEALEDARVDPARYDRYDLGV
                     ITASGCGGFEFGQRELQKLWSEGPQRVSAYQSFAWFYAVNTGQLSIRHGMRGHSSVVVA
                     EQAGGLDALAAARRQVRRGTVRVALAGGLDAPLSPWGLTAQIPNGLLSEADDPHRAYLP
                     FDRRASGYVPGEGGALLVLEPASAARERGAPTVYGEVAGYAATFDPPPHSGRGPNLAPA
                     IRGALRDAGTDPAEIDAVCADAAGLPDRDAEEAAALVEVFGRRAVPVTAPKTLIGRTYA
                     GGGPLDVISALLMMRDGVIPPTANVGEVPDDYGIDLVLGDPRARPVRRVLVVARGHGGF
                     NAALVLTRT"
     aSDomain        complement(16727..17785)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB17_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="8.40E-34"
                     /label="idmB17_PKS_KS.1"
                     /locus_tag="idmB17"
                     /protein_end="406"
                     /protein_start="53"
                     /score="109.1"
                     /tool="antismash"
                     /translation="EIRGFDARGRVPRRLLPQTDRVTQYALAAAEEALEDARVDPARYD
                     RYDLGVITASGCGGFEFGQRELQKLWSEGPQRVSAYQSFAWFYAVNTGQLSIRHGMRGH
                     SSVVVAEQAGGLDALAAARRQVRRGTVRVALAGGLDAPLSPWGLTAQIPNGLLSEADDP
                     HRAYLPFDRRASGYVPGEGGALLVLEPASAARERGAPTVYGEVAGYAATFDPPPHSGRG
                     PNLAPAIRGALRDAGTDPAEIDAVCADAAGLPDRDAEEAAALVEVFGRRAVPVTAPKTL
                     IGRTYAGGGPLDVISALLMMRDGVIPPTANVGEVPDDYGIDLVLGDPRARPVRRVLVVA
                     RGHGGFNAALVLT"
     CDS_motif       complement(17240..17278)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_idmB17_0001"
                     /evalue="4.60E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="idmB17"
                     /protein_end="235"
                     /protein_start="222"
                     /score="13.3"
                     /tool="antismash"
                     /translation="FDRRASGYVPGEG"
     gene            complement(17947..19206)
                     /gene="idmB18"
     CDS             complement(17947..19206)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (5-390). E-value:
                     3.8e-55. Score: 179.4. Matches aSDomain:
                     nrpspksdomains_idmB18_PKS_KS.1"
                     /codon_start=1
                     /gene="idmB18"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ene_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     707.1; E-value: 1.5e-215)"
                     /gene_kind="biosynthetic"
                     /product="beta-ketoacyl synthase"
                     /protein_id="BBE36466.1"
                     /sec_met_domain="t2ks (E-value: 4.9e-217, bitscore: 712.1,
                     seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 8.8e-51, bitscore:
                     164.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 1.6e-46, bitscore: 150.3,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 2e-43, bitscore: 140.1,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 8.4e-45, bitscore: 144.6,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 6.6e-50, bitscore: 161.4,
                     seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 6e-29, bitscore: 92.2,
                     seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKAVITGLGVVAPGGGLGAKPFWEQITSGRSATRAVTLFDATGY
                     RSRIAGEVDFDPVAAGLSEDQAGRLDRMIQFALVALREALDDSGLVAAPPSPSRTGVSL
                     GTAVGCTMGLESQYATVSRHGRDWLVDHTLAAEQLFDYFVPSSLAREVAWAAGAEGPST
                     VVSTGCTSGLDAVGHALELIRDGAADIVITGASDAPLSPITYACFDALRATSPDNDDPA
                     GACRPFDRTRNGFALGEGAAVMVLEESGHARRRGAHAYAEFAGFATRCNGYHMTGLSVD
                     GTEMAEAITAAMWQAQVVPDDIDYVNAHGSGTRQNDLHETAAFKRALGRAAHGVPISSI
                     KSMIGHSLGSVGSLEIAACALAVEHGLLPPTANLHEPDPECDLDYIPLVARECRTDVAL
                     TVGSGFGGFQSAAVLRRPEV"
     aSDomain        complement(18037..19191)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB18_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.80E-55"
                     /label="idmB18_PKS_KS.1"
                     /locus_tag="idmB18"
                     /protein_end="390"
                     /protein_start="5"
                     /score="179.4"
                     /tool="antismash"
                     /translation="ITGLGVVAPGGGLGAKPFWEQITSGRSATRAVTLFDATGYRSRIA
                     GEVDFDPVAAGLSEDQAGRLDRMIQFALVALREALDDSGLVAAPPSPSRTGVSLGTAVG
                     CTMGLESQYATVSRHGRDWLVDHTLAAEQLFDYFVPSSLAREVAWAAGAEGPSTVVSTG
                     CTSGLDAVGHALELIRDGAADIVITGASDAPLSPITYACFDALRATSPDNDDPAGACRP
                     FDRTRNGFALGEGAAVMVLEESGHARRRGAHAYAEFAGFATRCNGYHMTGLSVDGTEMA
                     EAITAAMWQAQVVPDDIDYVNAHGSGTRQNDLHETAAFKRALGRAAHGVPISSIKSMIG
                     HSLGSVGSLEIAACALAVEHGLLPPTANLHEPDPECDLDYIPLVA"
     gene            complement(19208..19600)
                     /gene="idmB19"
     CDS             complement(19208..19600)
                     /codon_start=1
                     /gene="idmB19"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MannoseP_isomer"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C5-C18
                     (Score: 171.8; E-value: 1.4e-53)"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide cyclase"
                     /protein_id="BBE36467.1"
                     /sec_met_domain="MannoseP_isomer (E-value: 4e-08, bitscore:
                     24.6, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDVPASRRLGADIRFLLTEKSVGARSGFLGTMTLEPGEYVSAHY
                     HPYSDEFVFLAEGSLRMRVDGEDILVERHEAVLVPKGAHHRYENVGDSTAFLVFQVAPL
                     APSPEEGHVEVEPVPQPSAQPPSVGS"
     gene            complement(19618..19968)
                     /gene="idmB20"
     CDS             complement(19618..19968)
                     /codon_start=1
                     /gene="idmB20"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225: Polyketide synthesis cyclase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C21/C2-C23|C2-C19 (Score: 135.1; E-value: 1.9e-42)"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide cyclase"
                     /protein_id="BBE36468.1"
                     /transl_table=11
                     /translation="MQRVLFVDRMRPDDAPAVAEAWAAHDRTGLPEEIGLASRTLFRFH
                     GLYAHLVEGRPELEGDLLEHIFAARAHPAFAEIRDRLGSHLTPYSPAFRTLKDTRAEEF
                     YSWRADITGATR"
     gene            complement(20146..21678)
                     /gene="idmB21"
     CDS             complement(20146..21678)
                     /NRPS_PKS="Domain: AMP-binding (12-415). E-value: 1e-73.
                     Score: 240.2. Matches aSDomain:
                     nrpspksdomains_idmB21_AMP-binding.1"
                     /codon_start=1
                     /gene="idmB21"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="BBE36469.1"
                     /sec_met_domain="AMP-binding (E-value: 5.9e-78, bitscore:
                     253.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSERTLYDWFTGSVAQHPDACALEVADARLSYRELDLLVRHLAVD
                     ITRTLGAVPARVGVHANRSLTAYVAYLAAQRLGATAVPLNPSFPRSRRVRVAALADVDL
                     VVAQERATYPVPVLVAEDDALLERVGRPAPEAPGRAARAADVAYTLFTSGSTGVPKGVP
                     IRHSNVDAYLGHVIPRYGLGPGERVSQTFDLTFDLSVFDLFATWGSGATLVVPTRRELL
                     APARFVAARRITHWFSVPSVISMALRLGRLPEGGMPGLRWSLFCGERLTLEQARAWRAA
                     APGSVLENLYGPTELTLSCTQFRLPEAPGDWPRTANGTVPIGTPYPGLEHLVIDDRGAA
                     ATRGELCVRGPQRFAGYLDPAHNRHRFLRFDGVRATPADAGPRPAAELWYRTGDLVTET
                     DRVLVHLGRADHQVKVQGYRVELGEIEAELRRQDGVEDAIVVALTEPDSGPVTLHAVCT
                     GANADTDGLLAALRERLPAHMLPRDVVHWARLPLNPNGKVDRAAIVTRLDPD"
     CDS_motif       complement(20401..20466)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_idmB21_0003"
                     /evalue="3.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="idmB21"
                     /protein_end="426"
                     /protein_start="404"
                     /score="35.2"
                     /tool="antismash"
                     /translation="HLGRADHQVKVQGYRVELGEIE"
     aSDomain        complement(20434..21642)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB21_AMP-binding.1"
                     /evalue="1.00E-73"
                     /label="idmB21_AMP-binding.1"
                     /locus_tag="idmB21"
                     /protein_end="415"
                     /protein_start="12"
                     /score="240.2"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="SVAQHPDACALEVADARLSYRELDLLVRHLAVDITRTLGAVPARV
                     GVHANRSLTAYVAYLAAQRLGATAVPLNPSFPRSRRVRVAALADVDLVVAQERATYPVP
                     VLVAEDDALLERVGRPAPEAPGRAARAADVAYTLFTSGSTGVPKGVPIRHSNVDAYLGH
                     VIPRYGLGPGERVSQTFDLTFDLSVFDLFATWGSGATLVVPTRRELLAPARFVAARRIT
                     HWFSVPSVISMALRLGRLPEGGMPGLRWSLFCGERLTLEQARAWRAAAPGSVLENLYGP
                     TELTLSCTQFRLPEAPGDWPRTANGTVPIGTPYPGLEHLVIDDRGAAATRGELCVRGPQ
                     RFAGYLDPAHNRHRFLRFDGVRATPADAGPRPAAELWYRTGDLVTETDRVLVHLGRADH
                     QVKV"
     CDS_motif       complement(20578..20649)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_idmB21_0002"
                     /evalue="5.30E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="idmB21"
                     /protein_end="367"
                     /protein_start="343"
                     /score="12.5"
                     /tool="antismash"
                     /translation="GELCVRGPQRFAGYLDPAHNRHRF"
     CDS_motif       complement(21181..21240)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_idmB21_0001"
                     /evalue="1.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="idmB21"
                     /protein_end="166"
                     /protein_start="146"
                     /score="27.0"
                     /tool="antismash"
                     /translation="AYTLFTSGSTGVPKGVPIRH"
     gene            complement(21688..22158)
                     /gene="idmB22"
     CDS             complement(21688..22158)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (6-145). E-value: 9e-19.
                     Score: 60.2. Matches aSDomain:
                     nrpspksdomains_idmB22_Polyketide_cyc2.1"
                     /codon_start=1
                     /gene="idmB22"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C9-C14
                     (Score: 234.0; E-value: 1.3e-72)"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide cyclase"
                     /protein_id="BBE36470.1"
                     /transl_table=11
                     /translation="MASDTDNSVHIEAPIDLVWRLTNDVRTWPELFTEYASVEVLAERG
                     NTVRFRLTMHPDPDGSVWSWVSERTTDPLNHTVSAHRVETGPFEFMRINWEFTPEGNGT
                     RMRWRQEFAAGPDAPFDDAGITKRINDNTAIQMAVIKEKVETAARTAARGAR"
     aSDomain        complement(21724..22140)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB22_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="9.00E-19"
                     /label="idmB22_Polyketide_cyc2.1"
                     /locus_tag="idmB22"
                     /protein_end="145"
                     /protein_start="6"
                     /score="60.2"
                     /tool="antismash"
                     /translation="NSVHIEAPIDLVWRLTNDVRTWPELFTEYASVEVLAERGNTVRFR
                     LTMHPDPDGSVWSWVSERTTDPLNHTVSAHRVETGPFEFMRINWEFTPEGNGTRMRWRQ
                     EFAAGPDAPFDDAGITKRINDNTAIQMAVIKEKVE"
     gene            complement(22158..22409)
                     /gene="idmB23"
     CDS             complement(22158..22409)
                     /NRPS_PKS="Domain: PKS_PP (7-76). E-value: 2.6e-08. Score:
                     26.1. Matches aSDomain: nrpspksdomains_idmB23_PKS_PP.1"
                     /codon_start=1
                     /gene="idmB23"
                     /product="acyl carrier protein"
                     /protein_id="BBE36471.1"
                     /transl_table=11
                     /translation="MATTSTTLSKLRTVLTEHIGLDQQTVSGAGDSSLTELGVDSIGVI
                     ELEKELFEPHGVDMPEEAPTMTITQIAAYLDGATRSED"
     aSDomain        complement(22182..22388)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB23_PKS_PP.1"
                     /evalue="2.60E-08"
                     /label="idmB23_PKS_PP.1"
                     /locus_tag="idmB23"
                     /protein_end="76"
                     /protein_start="7"
                     /score="26.1"
                     /tool="antismash"
                     /translation="LSKLRTVLTEHIGLDQQTVSGAGDSSLTELGVDSIGVIELEKELF
                     EPHGVDMPEEAPTMTITQIAAYLD"
     gene            complement(22443..23489)
                     /gene="idmB24"
     CDS             complement(22443..23489)
                     /codon_start=1
                     /gene="idmB24"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET C11O
                     (Score: 505.8; E-value: 1.1e-154)"
                     /gene_kind="biosynthetic-additional"
                     /product="methyltransferase"
                     /protein_id="BBE36472.1"
                     /transl_table=11
                     /translation="MEANAETAPRNPVPDDLHAQHLLLLACSGRLSQIVEVLVELEVAD
                     HLAPGPLPVEELAERAGAHPDALYRVLRCAASVGIFAEGPAHVFSSTPLADGLRSDNPD
                     GVLPLVRYNRMELTERPYASFLHSVRTGEPVFRQAFGSTFIEYLEQNPGIDDFYDGFMS
                     HWSRQFAAEELNQWDLGRFRRIADLGGGDGFFLAQILKRHPDTTGVLVDLPHVAKKAAS
                     VLAEEGVADRAEIRAGDLLKDPLPEGCDGYLLKAVLHDFDDAEARRILTGVRESMPDSS
                     ARLLVVDSILDPGNAWDHGKFLDLDMLVLHGGRERNLDDWRELFAAAGFELLSEPIYHW
                     TLLECRPV"
     gene            complement(23538..23792)
                     /gene="idmB25"
     CDS             complement(23538..23792)
                     /NRPS_PKS="Domain: ACP (11-78). E-value: 2.7e-10. Score:
                     32.4. Matches aSDomain: nrpspksdomains_idmB25_ACP.1"
                     /codon_start=1
                     /gene="idmB25"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 99.8; E-value: 1.5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /product="acyl carrier protein"
                     /protein_id="BBE36473.1"
                     /sec_met_domain="PP-binding (E-value: 2.1e-10, bitscore:
                     32.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREITVEELFELTRERAGEPEERELNADVLDVVFEHLGYDSVALL
                     EVLSEIRHRYGIELADEAMSRGRTPREVLEAVNGVIRDR"
     aSDomain        complement(23559..23759)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB25_ACP.1"
                     /evalue="2.70E-10"
                     /label="idmB25_ACP.1"
                     /locus_tag="idmB25"
                     /protein_end="78"
                     /protein_start="11"
                     /score="32.4"
                     /tool="antismash"
                     /translation="LTRERAGEPEERELNADVLDVVFEHLGYDSVALLEVLSEIRHRYG
                     IELADEAMSRGRTPREVLEAVN"
     gene            complement(23830..25059)
                     /gene="idmB26"
     CDS             complement(23830..25059)
                     /codon_start=1
                     /gene="idmB26"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     conventional flavin-dependent halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_functions="biosynthetic-additional (t2pks) HAL
                     (Score: 392.8; E-value: 4.5e-120)"
                     /gene_kind="biosynthetic-additional"
                     /product="tryptophan halogenase"
                     /protein_id="BBE36474.1"
                     /sec_met_domain="DAO (E-value: 5e-09, bitscore: 27.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /sec_met_domain="Trp_halogenase (E-value: 9.1e-28,
                     bitscore: 88.5, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEHHVRTTEYDVIVIGGGPAGSATAGLLARSGHDVLLLEREKFP
                     RYHIGESLITGCMGVLEELGIRERVAALGFVEKYGGSLVWGRDGRWRFAFAEGKPEFPH
                     AYNVRRADFDALVLTRARELGAHVLEQATVKEAVVDNGRVVGVRYVVRGGEEGEARARM
                     VVDASGQARVLGRTLGGVDWQDDLRNVAVWSYYQDGEPLAGDETGNIFVEHVPGGWFWY
                     IPLHDGTHSVGFVTAAEDAAATGLELPALFEAKVEESVHLKQYMKRAKRTDAFRTARDW
                     SYVCREFAGPGWMLVGDAAGFVDPLFSTGVTLAMLAGRAAAEAIPVILKDPERESTVQA
                     RYDKSYREFLGTILSFVRYFYDVGLDRDAYYQYAQALVDPGQLFFPRKDFVTLISGLNS
                     LQPVFDLDVD"
     gene            complement(25223..27139)
                     /gene="idmB27"
     CDS             complement(25223..27139)
                     /codon_start=1
                     /gene="idmB27"
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /product="regulatory protein"
                     /protein_id="BBE36475.1"
                     /transl_table=11
                     /translation="MQFRLLGNLEIESGDGRIVPLAPKLRTILSLLLTLNNQTVPVSRL
                     IDELWPDEPPTTVVATIQTYVYQLRKILESRKFAKEKVPSLVTETSGYRLNVLPESIDS
                     HVFERCFREGRLAFEAGDFERSARALHAGLSLWRSSAFADVTMGPRLEAYATQLEEARL
                     QAIELRVDAKTELGQHQEVVRELKALTIAHPLHEGFQAKLMLALYRLGRRHESLDTYAR
                     LRTNLVEALGVEPTAATQRLHRALLAADDSVDEFLGAPRASSAAVHVHPAQLPADIPDF
                     TGRTALLARTERLVLDCVDDTATNITVLTGRTGVGKTAFAVRLAHRLKRRFPDGQFYAS
                     LTDDNGEPADPRRLLGDFLRSLGFTPEQIPDTLEARSQLFRSWSADRGVLMVLDDALSE
                     REARPLVPGGAHCAVLVSSCQSLPGLSGARVVEVDPLAPNEAVELLGRIVGRRWNDGDL
                     PTLRTIVDKCECLPLALRAIGSRLCAPTHVSLEACAARLVDRHRRLSELRSGDLDLRAR
                     LARGRRQLTPATRGCLAPLSRETSTTFTSREAADILRCSTVQAEVALLEASQIRLVLPV
                     GENGDGDMLFRIPDVVRIYFMEESGRGPLPERGGHRGMHVTEGSRSATTSAYWPTRTVG
                     AAT"
     misc_feature    complement(27065..27067)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(27459..28463)
                     /gene="idmB28"
     CDS             complement(27459..28463)
                     /codon_start=1
                     /gene="idmB28"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     46.9; E-value: 6.4e-15)"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-2,3-ketoreductase"
                     /protein_id="BBE36476.1"
                     /transl_table=11
                     /translation="MTARTDVVYKSLGRTALQVSTPCLGTLNLGVRTTEDEGHALMDHA
                     LDNGVNFVDTADTYGWQVHRGYTEELIGRWFAQGGGRRERVVLGTKVFGAMGDGPNDGG
                     LSARHIVAACEDSLRRLRTDWIDLYQMHHVDRRAPWEEIWQAMELLVAQGKVRYVGTSN
                     FAGWHLAAAQESANRRHFLGVVSEQCVYNLVTRHVELELIPAARAYGIAVLAWSPLHGG
                     LLGGALRKLADGTAVKTAQGRAMEALDGHRSALAAYEKLCAELGESPARVGLAWVMSRP
                     GVTAPVIGPRTVEQLDDALWAACLKLPEEVLTRLDELFPPVGKGGPAPEAWCW"
     gene            complement(28460..29257)
                     /gene="idmB29"
     CDS             complement(28460..29257)
                     /codon_start=1
                     /gene="idmB29"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-4-ketoreductase"
                     /protein_id="BBE36477.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.2e-09, bitscore:
                     26.1, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIVGSGFLARHLAPLTEAHDEVVAFAAGPSSTRATDAAEFDREA
                     AALYAWVRRCRADGRLLLYFSTASASMYGGAEGPGREDGPVLPGSAFGRHKLAMEGVLK
                     ASAPRHLILRLGHAAGPGQRPHQLVPALVRQVVAGRVLIQRGACRDLIAVAHAVGLVER
                     LLSAGVVNDVVNVASGTAVSVEEIVTHLEGRIGVRARREYVRAAGPQTPVSVDRLRRLL
                     GGGEGVPPFPGDYYRTVLDACLTADSGSPVGVEPNPDRGGHRP"
     gene            complement(29257..30495)
                     /gene="idmB30"
     CDS             complement(29257..30495)
                     /codon_start=1
                     /gene="idmB30"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_functions="biosynthetic-additional (t2pks) GT (Score:
                     399.3; E-value: 5.6e-122)"
                     /gene_kind="biosynthetic-additional"
                     /product="glycosyl transferase"
                     /protein_id="BBE36478.1"
                     /sec_met_domain="MGT (E-value: 1.4e-129, bitscore: 424.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILFATWAWATHYFPMVPLARAFDSADHEVLVASQPALADTVLR
                     SGLVPIPAGEDFDLIGEFQGNPWLMADQRTNPRSAPLTWDEAAIRKRRHFIGFFCRIAE
                     LMLDDLLRIARRWQPDLLVWDALTFAAPVVAQACGVPHVRMPWGLDILGTQPPDLEERL
                     RPQELLDLYARAGQRPAAHLAPWTIDICPPDLQIANESPRLPMRYVPYNGLGGVLPDWL
                     LEPVRATRRVCVCWGTSTTRFFGPDHYLVPGILEGLADYDAEIVVAATPDQRPLLGDLP
                     ANVRVAESLAISALMPSCSAFIHQGGAGTTLTAAHAGVPQLVVPQVFDQRTDAEQLAGT
                     GAGRFVLGQELTPQSVRRELDALLADPGYAKNAVRLRDQLRSLPTPADLVPVLTRFAAD
                     PAGFAPETARAAH"
     misc_feature    complement(29368..29370)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(30747..31166)
                     /gene="idmB31"
     CDS             complement(30747..31166)
                     /codon_start=1
                     /gene="idmB31"
                     /product="hypothetical protein"
                     /protein_id="BBE36479.1"
                     /transl_table=11
                     /translation="MTEKAVYTAEAIATGDGRAGRVRTVDDGLVLDLALPPALGGSGRG
                     SNPEELFAAGYAACFHNALRMVARRAKADVEGSQVTGRVTLLQEGWDFRLSVHLTVDVP
                     GARLEEARKLAEEAHQACPYSKAIRGNVTVETELV"
     gene            31597..33072
                     /gene="idmB32"
     CDS             31597..33072
                     /codon_start=1
                     /gene="idmB32"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 228.7; E-value: 3.3e-70)"
                     /gene_kind="biosynthetic-additional"
                     /product="dioxygenase"
                     /protein_id="BBE36480.1"
                     /transl_table=11
                     /translation="MELFRTVGIQQAVWDVAEKVVLGKYWSETDLPPRQLPRAILRANS
                     LADVVAGNVVVMEEGANLFTNVGPVEPVWCGQDRVEPIMLREARRRGAHIDFNTEMLSF
                     TADAEGVSARVRDRGTGEETSVRAKYLIGADGAGGKIRTEVGIERRGNGTVGHVLNVLF
                     KADLDGILGGRRFLILYLSHPEAAGMLFKLDDERWIFGWFCGPEQIEEGRVTDAECVDL
                     IRKATGEPQLSVDIHMTMGWWMAHEIVDSYRSDRVFLTGDACHVLPPTGGFGANAGIQD
                     ANNLAWKLAGVLNGWADEKLLDSYEAERRPVGRATADQAWMRHTQWSDPGAANRHDQRD
                     QTVVTTAYRYSSDAVVGARHDEVFGHDLTIDGRPGMRVPHVWVTSGGEQVSTVDLAGTG
                     FALLAAADGARWAGAAETVAQRLGVPLTARRVAPDGDLTAPRGALASVCGIEETGAVLV
                     RPDGFVGWRSPGLPADPTAELHDALARIVGRQT"
     gene            33114..33437
                     /gene="idmB33"
     CDS             33114..33437
                     /codon_start=1
                     /gene="idmB33"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="BBE36481.1"
                     /transl_table=11
                     /translation="MATISAEKDYFTTINVFTTTPEHQQKVLEIISGAEEKMRDFPGFV
                     SASIHVSHDGTQVIGYAQWAKKEDFDGMRARADLQQHFQAVRKLVSSVDPIAARVTYTH
                     DGT"
     gene            33458..33778
                     /gene="idmB34"
     CDS             33458..33778
                     /codon_start=1
                     /gene="idmB34"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="BBE36482.1"
                     /transl_table=11
                     /translation="MARISVKDEYFTTINVFSTTPEHQKRLAEIVVEGAEAMKSHPGFV
                     SASIHLSYDGTRVVGYAQWASEDDFHGMRARADLQGHFEEVHELGTIESIACRVAYTSD
                     ED"
     gene            33825..34568
                     /gene="idmB35"
     CDS             33825..34568
                     /codon_start=1
                     /gene="idmB35"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /product="abhydrolase"
                     /protein_id="BBE36483.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 7.6e-10, bitscore:
                     29.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDALLAETVRFHGAGGDEIEGYLARPLAPGPFGGVVVIHHMPGY
                     DEATKQITRKFAARGFAALCPNLYYREAPGADPHDAAAAARANGGVPDDRLVGDAEGAI
                     AVLRSLTNANGKVGVIGYCSGGRQSFLAACSLPLDAAVDCYGAFVVGRPPEGMPLQIEP
                     IAHLTKDLSGPLLGLFGAEDTTPSPAETAELETELKRHGKTFEFHTYENAGHGFFDVDR
                     KTYRPKAATEGWQKVFDFFGRHLAS"
     gene            34605..34886
                     /gene="idmB36"
     CDS             34605..34886
                     /codon_start=1
                     /gene="idmB36"
                     /product="hypothetical protein"
                     /protein_id="BBE36484.1"
                     /transl_table=11
                     /translation="MCTYITEKLAASGSAKGAGGWFDLTEITVYFDHPQHAQEAHTLNI
                     DFLDPTQGASARVAVELTADTALALAEAVRSILASVPAGLLPEPAGQA"
     gene            34883..35824
                     /gene="idmB37"
     CDS             34883..35824
                     /NRPS_PKS="Domain: PKS_ER (23-182). E-value: 1e-24. Score:
                     79.2. Matches aSDomain: nrpspksdomains_idmB37_PKS_ER.1"
                     /codon_start=1
                     /gene="idmB37"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /product="quinone reductase"
                     /protein_id="BBE36485.1"
                     /transl_table=11
                     /translation="MSTALMRAVGFTAFGGPEVVSVAEVPVPEPGPGQVLVRVSAAPLH
                     FFDRAARSGALRSMLAEGPRYVLGWDMCGTVHTVGPGVVAFAPGDPVVGMVDWLTTRTG
                     TQAEYAVLDASALAPAPAGTTPAAASTLPLNALTATQALDLLRLDAGRTLAVTGAGGAV
                     GGYVVELAKDRGLRVVALSASRDEGFLTGLGAVFVPRSDDPAGALLAAAPEGVDGLVDG
                     ASLGDRVLPAVRDGGGFVAVRPPATPEPQRGIRTMPVITRGDGAQLRSLVDLVDKGRLT
                     LRVARTFAYEEAHLAHEQLDRGGQRGRLVLLP"
     aSDomain        34952..35428
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_idmB37_PKS_ER.1"
                     /evalue="1.00E-24"
                     /label="idmB37_PKS_ER.1"
                     /locus_tag="idmB37"
                     /protein_end="182"
                     /protein_start="23"
                     /score="79.2"
                     /tool="antismash"
                     /translation="EVPVPEPGPGQVLVRVSAAPLHFFDRAARSGALRSMLAEGPRYVL
                     GWDMCGTVHTVGPGVVAFAPGDPVVGMVDWLTTRTGTQAEYAVLDASALAPAPAGTTPA
                     AASTLPLNALTATQALDLLRLDAGRTLAVTGAGGAVGGYVVELAKDRGLRVVALS"
     gene            35870..36709
                     /gene="idmB38"
     CDS             35870..36709
                     /codon_start=1
                     /gene="idmB38"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /product="hypothetical protein"
                     /protein_id="BBE36486.1"
                     /transl_table=11
                     /translation="MQIGIGLPSNIPGVRRTQLLEWARRAEARGFSTLAANDRLVYDNL
                     EPLIALSAAAAVTTRIRLATTILIAPLRANPVLLAKQAASLNRLADGRLTLGLAPGGRQ
                     DDFTTSDLDFHTRGHTLDHHLTRLHDTWNNPDIGPHHTTPRLLIGGFTPTSFTRAATHA
                     DGWIAGGGDPDFFRHCAQQAHTAWHTAHRTDTPHLTATSHFVIGAEAEARARRFLLDYF
                     AFAGPHAREIVDSSLKVDEADIKATVDACANAGADELILFSVDPDPDQVDRLADIVL"
     gene            36734..37780
                     /gene="idmB39"
     CDS             36734..37780
                     /codon_start=1
                     /gene="idmB39"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     (Score: 214.2; E-value: 6.3e-66)"
                     /gene_kind="biosynthetic-additional"
                     /product="methyltransferase"
                     /protein_id="BBE36487.1"
                     /transl_table=11
                     /translation="MADTSTATAQQAAQELRDALQAGFTAQLLRAFVRLGIADLLADGP
                     RDLPTLTKALGAHPGALAGFLGACAGEGLVEGEADGRITVTERGLLLRPSGSLGQQALW
                     VAGPGASRTYEHITEVVRTGKSGGEAAGQHLYDYYAAHLEEATAYEEVMSELTEGCIDA
                     LLEAYDFTAHRRIVDVGGGRGTLLARVLERAPEATGLLYDAPYVVDMARGAQKARTEGG
                     EDGRLEFAAGDFLESVPGGGDLYVIKSILCDWGDEEAARLLRNVHEAAPEGSELLIVDW
                     FRPEPRDGAAQGLSSGGFFIWTLLGGRLRTATEMEDLVRTAGFKITRREPDFAPGFFSW
                     NFLAATRD"
     misc_feature    36779..36781
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 atgtatggcc tgtggtggcg gctgaatcac tgggtgcgct gtgtgatcac ggcgctggtg
       61 cgtgggctgg cggcgatggg gcgccttcac gtcgggggcg aggagtgcga ccccttcccc
      121 ttcaggaccg gccggctgtc cgctccgccg gcgcggcacc ctgagcggtt gcggcccgat
      181 cttccaccca ccgcgctgga acggagcctc gagcacgtgg tgcgcggctt cccgtggtcc
      241 ggtcgtacgc ggcactcggg tcgtacgcgg cactcgggcg cccagcgtct acgaggccgg
      301 ccgccttctc cgcccggcgg tcctgccgga tgaccgaaag ggacttgttc cgcgagccgg
      361 cggagccggg tgccgcgggg ctgctcccca ggcccgaagt gttctgacgg tcgccgctga
      421 gccgtactcc ggggcttcgc acatggcgtg aactagcgac gctagaggct acctaacggt
      481 gctagtgtca atctatcggt gctagacgaa aggatcgggt ggagatgaag ggcgcaaaat
      541 tcgcgctggg gggccggagc tcattccgga ccccggcccc tgcaaagacc gactggtggc
      601 ccctgaccgc catcggcctc gccgtgttca tgctcatgct ggatgccacc gtggtgacgg
      661 tggccctgcc cgacatggca aaggacctgc acgccgatct cacggacctg cagtgggtca
      721 tgaacgccta caccctcgcg atgtccggcc tccagctcac ctcgggctcg ctggccgacc
      781 gcctcggacg gcgccggctg ttcctcgtcg gcgtggcact cttcgccgtt gcctcgctcg
      841 cgtgcggtct ggccaccacg gcggccgtgc tcatcggcgc ccgcatcgtg cagggcctcg
      901 ccggtgccct gatgttcgcc accacgctgg ccctgatcgg ccagtgctac acgggccgca
      961 accgtggcgt ggccttcggc gtgcgcggca ccatcgcggg cgtcgccgtc gtcctcggcc
     1021 cgctcctcgg cggcgccctt atcgcctggc tgaactggcg ctggatcttc ctcgtcaacc
     1081 tgccggtcgc ggtggtcacc ctcgctctcg gctgggccaa gctgccgcgc cgcgagttgc
     1141 tggagaagcg ccgccggatg gacgtcggag ggccggtgac gctggccgcg acgctgacgc
     1201 tgctgatgtt cgcgctgctg cgcggaaccg aggacggctg gtcgagcacc cgcatcatgc
     1261 tgctgttctc cggcgccgcc gtgtccttcg tcgccttcct gctcgtcgag cgcgcccacc
     1321 gcgaccccat gctggacctg agcctcttcc gcatcccgtc cttcacgggc acgcagatcg
     1381 ggtcctttgc cgtccagggc agcatcttcg ccctgttcgt gtacctgtcc ctctacttcc
     1441 agagcgtcct cggctactcc gcgatgcgcg ccggcctgtg cttcctcgct gtggtcgtgc
     1501 cgatcctgat cgccggtccg ctggtcggcc agttcatgga caagctgcca cgacgcctcc
     1561 tcgtgacggg ctccctgctg ctgctcggca ccggactcgt ggtcatgcac ggaatcacgc
     1621 cggcctccga ctggaaggac gtcgcaccgg gcatggccat ggcgggcttc gcctgcggta
     1681 tcgcactccc gacgctgggc tccctcgccg tcgaggtggc cgacgagcgc cggctgggca
     1741 tggcctccgg agtgaacaac accgtcctcc agatcggctt cgccatgggc atcgccgtct
     1801 acggtgcggt cctggcccgg tacggcacca ccaggaccga tttcatcgac gggctgaacc
     1861 agctgttcct gctcgctgcc gcggtcgcct acggaggtgc gctgatcacc ttcctgctca
     1921 tccgcccccg accgcgccgc tgaccgtcac acgcccgaat ccctcatctc gccgagccag
     1981 aaccgaatcc ctcgaggagc cgtcgatgac gcgagcgacc ccccggctgc gccccatcgt
     2041 gaagtacctc gcaagccgag acgcattgca cgatgggtgg acggggggtc ttcccgtgga
     2101 ccaccgtgcc cacctcaacg agtcgcccta cccgccgctg cccagcgtcg tcgccacgat
     2161 ccgcgggacg gccgaccagg tgaaccgcta tcccgacacc gggaacacgg aactcgccgc
     2221 cgccatcgcc gaccgcttag gggtgccggc cgcccatgtc accgtggggc cgggcagtac
     2281 cgcgctgatt caccagctgt tcctcgccgc ggtcgcaccg cgagagaccg tcgtcctcac
     2341 cgacccgtgc gccgaccggt acgccttcct caccctgctc agcggcgccc ggcccgtcca
     2401 ggtccggctc gaccgcggca gacaggacct cgcgtccatg ctgcacgcgg tgaaccgccg
     2461 tacccgggtg gtcgtcgtcg gtaacccgca cgatcccacc ggaaccctgg tggccgggga
     2521 gcatctgacc gagctgctcg ccgcgctgcc cagcgacatt ctggtggtcc tggacgagac
     2581 ctaccgggag ttcgtcggca cccggacgac acccgacggc gtcgaggcct accggctgtg
     2641 gcccaacgtg gtcgccgtcc ggtccttctc cgcggcacac ggcctcgccg ggctgcgcgt
     2701 cggcttcgcc ctcgcgcagc ccgccctgag tacggccctg cgcagcacgg ccctgcccta
     2761 cggcaccaca cgtctcgccg agctggcggc cctcgcctcc ctgcgggcga cggcggagat
     2821 gtccggccga atccaccggt tgaccggtga acgcgaccgg ctgcgctccg tgctgcgcgc
     2881 acagggctgg acgattcccc acagccaggc caacttcctc tggctgccgc tcggtacacg
     2941 gtcggtcgcc ttcgcccggg cctgcggcga tcaggggatc gcggtgcgcg tatgggaggg
     3001 ccggggggtg cgggtcacga tcggcgaccc ggagtcgaac gatctgatcg cctatgtggc
     3061 ctcgcgattc cccccggcgt cctgatgcgg gtacctgccg gctcagtcgg ccttgcgggc
     3121 gacgatcagc cgttccgtcg ccgtcagctc ctggacgccg acctcggtga agcccgcctc
     3181 cgcgagccac tcccgtgcct cggccgcgct gtactcggag gcaccgctgc ggacgagctt
     3241 catgttgagg ctcatgagca ggctgcgggc cggcccgcca cggtcgtcgt cgatcagttc
     3301 gtcgtagacg agcagggaac cgcccggacg cagcgcggca tgggctcgcg cgaccagcag
     3361 acgccgcgtg tcctcgtccc agtcgtgcag cacatggccg aagagcagca cgtcggcctc
     3421 gggcagcgga tcggagcgga agtccccgcc gtggaacacc acccggtccg cggtgtccag
     3481 cgaggccatg tgctcggtga agaacggctc gagcgggggc aggtcgaagc agccgccctt
     3541 gaggtgcgga tgggccaggg cgatccggcc ggcgagattg ccgcgcgcgc ctcccaggtc
     3601 cacgaagttc tggtaccgct gccagtcggg ccacttcacc agttcggcgg tgaccgccgc
     3661 cgccgcgctg tccatggcgg acatgaaccc gcgcacccgg tcggggtccc ggtagaactc
     3721 gccgaaggag tcgtccccct cttgcaggtg tccggtgcgc agcagttcgg ggagtcggcc
     3781 ccaggccgga tagagcgact tgctcatgaa catgaggaag ccgcccacat agccgggctg
     3841 cttcgggtcg aggtggcgct cggtgacggg ggcgttgcgg tagtggtccc cttcccggag
     3901 gagcagtccc agtgcgccga ggctgtcgag caggtcccgc gcggcacgtt cgtgcaggcc
     3961 cgtgcgctcc tggagctcgg ccagggtcgc cggcccgtcg acgagcgcgc cgaacacccc
     4021 gcactccacg gcgctgaaca acacctggga ccgccagaaa ccggtggcgg tgtccagcag
     4081 ctgctgcagt ccgacttccg gggaatccgt tgactccatg gttctccctt ctcgccggtg
     4141 ccgaaatcct gtgcggccga ccggctggga cggaatggat cgacgggttt gatcgtcctg
     4201 ggcgccggtc gagaaggtct gaagacatgg taagtcgctc cgcccttccc tcgggtcgcg
     4261 ccggccccga gaattccggc atgactattt ctctcgtcac cggggcgaac aaaggcatcg
     4321 gatttcagat cgcgcgcggg atcggcggca ccgtgctggt cggggcgcgg gacgacaccc
     4381 gcggccgggc cgccgagacg gcgctgcggg aagcgggtgc cgacgcccac cacctccggc
     4441 tcgacgtgac cgaccaggac acgatcgacg ccgccgtgaa atgggtggcg gacacttatg
     4501 gcagcctgga cgtgctggtc aacaacgcgg gctgcccggc gctcgactgg gacgtgccgc
     4561 cgagcgaggt ctcgcttgac gcggtgcgca ggacgtacga cacgaacgtc gtcggtgtga
     4621 tcgccgtgac gaacgccttt ctgccgctgc tgcgcgaggc ccccgcggcc cgtatcgtga
     4681 acgtctccag ccggcttgcc tcattgacgc tcggcgcgga cgagaattct ccggtgagcc
     4741 gggtgaatct cctcgcctac aattcctcga aagctgcgct gaattcgatc acccaggcct
     4801 atgcgaagga actgagggaa acgcccgtca aggtgaacgc ggtcaacccc ggtttctgcg
     4861 cgaccgacat ggcggccgga atggcccggt acggaaaggg aatgcggacg gccgaggaag
     4921 gcgctcgccc ggtgatcgcg gcggccctgc tgaccgccga cggtccgacg ggcgcgttct
     4981 tcgacgagag cgggccactg ccctggtgac tcgccggcgc ggggcggcga ccaggccgtc
     5041 ccgcccccgc cgtaccggtc acgcgtcgcc gtgctcggcc gccagttcct cggagaaccc
     5101 gccgagaatg ccgttcagac ccaactcgaa gcggtccgac agaccgcgct ctgcaaggcc
     5161 gccggcgacc gccgtcacat tggggtagcg gtcgccgggc agaccggcga agaactcgcg
     5221 catctggtcg agccggacgc gcccctcggc gccctgaccg aaggcgacct cctggctgac
     5281 aaagccgatc gcgtagtaca gcagcacgag gtagcagtag ccggccagcc ggtcgccgaa
     5341 gtgggcgcgg cgcagggtgc cgatgacgct ttccgcgatg cgcagccagt tcgggcccag
     5401 cggaacccgg ccggtgagca accgggtggc cgccgggtgc agcagcagca cccggcgcat
     5461 ctcccgtgcg atctcggcca gttgggtgcg ccagtcgccc tcggcgtcgt cctcgggcat
     5521 gtcgcactcg ccgagcaccg cgtccaccac caggtcgtag agctcatcct tgctgcgcac
     5581 atgccagtag agggagggcg acttgatgtt cagcgccgtg gcgagccccc gcatgctgaa
     5641 cgcgtcgact ccctgcgact ccaggagctc cagggcgaca cggacgatct cggcccggtc
     5701 cagccgctgc tggtccatcg gctcgtcact ccacagaccg tccgggttcg gtcggatccg
     5761 aagcttggca cgtctggacc gctcggtcat aagcgcattc ccatcgtctc gcgtcgcgag
     5821 gaatctagca ccgctagggt actgcgggtc tcccggcaac gagtctgtca gttcgggttc
     5881 ggcggtctca acggacgcgg gacgatgttc gcgttaaacc ggaagacgtt ctcggggtcg
     5941 tggacgccct tcaccgcggc gagccggtcg taggtgtcgg ccccgtacgc cgtgcggatc
     6001 tgctccgcgg tctcgtcccc ggtgacgaag ttgacgtagg gcccaccgcg cacatacggc
     6061 cgtacggcat cggccgccgc cttggtccag ccggcgaggc ccgccgtccg gttctgccgc
     6121 gcggccaggg cgttgacgcc gagcagctgg acggcgtccc ggagggggac cggggtggca
     6181 tccgccggga cgcggcccgc gacgcccccg agaagctgca gctggatcat cgcgagggga
     6241 ctcggcggct gcccggccgt ctcgacgagc accttgacga gccgctcgtc gagacggccg
     6301 aggaaggcac tgtgcccatg ggcgcgcatg gcctccacgg tccggccggg cggctgctgc
     6361 agttcgagat acggccgggg gcgcacatcg gcgacggccg gcgttccgaa gccgcgcagt
     6421 tccgtgatca gccgctcgct cgcgggggac ggcgcgaagt cggcgacacc gatcatgacg
     6481 acgggcccgc cgcgcagttc gggcggcacg aacggcgcgg gcggggccgt cagcagggtc
     6541 gcgcgcaggg cgaggtggtc cggggcgcgg tcgcagacgt cctggtagtg cagcaagacg
     6601 tcggcggccc ggtcgtaggc atggaggacc gtgccggaga cgaccgtggc aaccggccgc
     6661 agccggaacc ggaaagcggt gacgacgccg tagttgccgc caccgccccg cagcgcccag
     6721 tagaggtcgg aatggctgtc cggcgcggcc gtcagggtct cgccggcggc cgtgagcacc
     6781 tcggccgaga gcaggttgtc gcaggtcatt ccggccgcgc gatgcagcca gccgaagccg
     6841 ccgccgaccg tcgtaccgcc cactccgacc gacggcacat cggcaccggt caccgcgagt
     6901 ccggccctct gggtcgcctc gtccacccgc ccccagaccg cgccgccgcc cacggtcagg
     6961 gtgcggcccc gggcatcgat gtcgatgccg gccagggcac ccagatcgag tacgacggcg
     7021 tcgtcggcgg taccgaatcc ggcgaggctg tggccgccgc cgcggacggc gacgggcagg
     7081 ccccggtcgg ccgcgaaccg cacggcgccg cgtactccgg ccaccgtgac cggcctgacc
     7141 acagcgagcg gtgctcggcg gacatccgtg ttccagaccg ctcgggcggt ctcgtagccg
     7201 gggtcgcccg gcagggcgca gggcacccgc gccgcgcgcg agagcgccga gcggacagcg
     7261 gaattcatgg gttcctccgg tgcaggtcgc ggtcggcgtg cagttcgggc cacaggccgt
     7321 tgcgcagggt cagcagcagg gtgcgcagct gcacgttcac gcagtagctg tgccgcagca
     7381 gggcggtgac ctcgtccagc ggggcccacc ggtagtcgtc cgggagcggc tcgtcgaacc
     7441 cgtccggtgc ctcgacgacc aggtagcggg tctcggcctg gtcgaagcgg ccgccctcct
     7501 cggagtggac gacatcgcag cggacccgtt cggcgggcat ggcgaggacg cggtccagat
     7561 agcgggtcgc ctgctcgggc ggcagcccgc gctcgtggtc ggggacgcac tgcacagtgg
     7621 gcccgagttc gaccacgtcc gtgagcccgg gttcctggcg ggcgtgcacg agcagcagca
     7681 gttccccgtc gacgcccctg cggaccgcca gcgcggcgag ggagcgggcg ccgacccgca
     7741 gcagcggctg ggaccagccg gcgacctcgc ggctggccgc cgcgacctcc acggccacga
     7801 tggagaagcc gcgtccgtcg ggtcgtccga ccgtgtccgc cgatcgccgc cagctcggca
     7861 cgtcgtgcaa cggcacgacg gtctggacga gttcgtgccg ggtgcgcatc tcggtcatcc
     7921 agttcagcaa cctgacggcc cggtcctggc ccggggcggg gtcggcgagc gcgaggcagg
     7981 acaggacggt gcgcgcgtcc atgttgacga ggttgtcctg gtgcagcagc cgcagcagtt
     8041 gaccgacggt cagccagcag aagtcctcgt gctccggcgg accgtccatg acctcgacga
     8101 tcatgttgcg gttgcgcttg cgcaggaagt agtggccgtg ttcggactgg agcgagtcgg
     8161 ccacgacggc caccggccgg tcaccggtga agaactccag gtgccggggg cgccggccgc
     8221 cgtgcaccat cgtgtagttg ctgcgcgtcg cctgcacggt cggcgacagc tggacgaggt
     8281 tgatgttgcc gggttccatc ttcgcctgca tcaggcagtg caggacgccc tcgaactcgc
     8341 gcaccacgat gccgaggatg ccgatctccg gctggttgag gatgggctgg cgccagctgc
     8401 cgtggcgcgg gtcgtcggtg cggacgcgca gtccctcgac ggtgaagaac cggccgctgt
     8461 cgtgtccgag gttcccggtg ccgggatcga agcgccagcc cttgagtgtc gcgaagggca
     8521 cccgccggac cgcgtggtcg tgtgccgcgc tccgttccgc gaaccactgg gggaaccggt
     8581 ggttgggcat caaccggctg tcggtcacgg cctcggactc ggccagccgc agggccatgc
     8641 cctcgcgcag cgttcctcgt acctcaggca tcgggacctc ccggccgggt acggagcatc
     8701 gaggtcgcgg gcgccctcgt accccgtgcg ggggagccga cggacccggc cctgtctgtc
     8761 accaggatgc gcatcagacc tccacgtagg tgtgatcgcc gaccaggaag cagcggtcgg
     8821 tgcgagggtg ggtggcacgg acctcggcgc cacggccgat caccgagttg tggacgccgt
     8881 ccagtccggc catgacggca ccgtcgagca gcaccgaccc ggtgatctcc gtgtcgctca
     8941 cccggcagtc gcggccgatg gcggtgtagg gcccgacccg gctgtcacgc acgacgcttc
     9001 cggcgccgac gaggaccggc ccgatcagcc gggaccgcag gacgctggca ccggattcga
     9061 cgaccaccgt gccgtcgagc cggctcgcgg cgtccacgct cccggcccgc tcgggcgcca
     9121 gggcctccat gagcacccga ttgcagtcga gtacggcctc gacgtcgccg acgtccttcc
     9181 agtaaccggt caccggggtg ctcagtacgg tggcgccgtc cgcgaccagc gccgagagcg
     9241 cgtcggtgat ctccaactcg ccgcgggcgc tgggacgcag gcccgcgacg gccttgtgga
     9301 cggccggcga caggaagtag acgccggcca ggacgaggtc gctgcgcggc acccggggct
     9361 tctcggccag ggcgagcacc ctgccgcgac cgtccacctc gaccacgccg tactgacggg
     9421 gatcggcgac cttggccgtg agcacgacgg cgtccgggcc ctcgcagacg aaccgttcgt
     9481 gggccgcggc cagtccgtcg gtgaccacga cgtccccgag gcacaggacg aaactgtcgt
     9541 cgccgaggaa cgcccgggcc agcgcgacac agtgcgcgag gccgagcggc tccggctgcg
     9601 gtacgtaggt gacggacagc cccaggcccg agccgtcacc aaggacggcc tcgatctgcg
     9661 ggcggccgtc ccccacgatc acggcggcct cggagacgcc gagcgcgggc aactgctcca
     9721 gacaacggac gagtacgggt ttgccggcga ccggcatcaa ctgcttgggc agtgcgggag
     9781 tgaacgggcg cagacgagta ccccgcccac cggcgagcac cagggcccgc aggcgtcgcc
     9841 ggctcacccc actgcgtccg cgagcaggtc gacctgacgg gggtcggggt cgacagggaa
     9901 gaggatcagc tcgtccgcgc ccgcggcacg ccattcctcg accgccgcgc tcaccttctt
     9961 cttggttgtg agcacgcccg cggcgatgcg gtcggccagt gacccggcga aggagtagta
    10021 gtcgcgcaga tagtccccgg cacgtggttc ggcgtcgggt cccagaccga aatagcaggt
    10081 ggcggtgagg tggggggtgt cggtgcggtg ggcggtgtgc caggcggtgt gggcttgttg
    10141 ggcgcagtgg cggaagaagt cggggtcgcc gccgccggcg atccagccgt cggcgtgggt
    10201 ggcggcgcgg gtgaaggagg tgggggtgaa gccgccgatg aggaggcggg gggtggtgtg
    10261 gtggggtccg atgtcggggt tgttccaggt gtcgtggagg cgggtgaggt ggtggtcgag
    10321 ggtgtggccg cgggtgtgga agtcgaggtc gctggtggtg aagtcgtcct gtcgtccgcc
    10381 gggggcgagg ccgagggtga ggcggccgtc ggcgaggcgg ttgagggagg cggcctgttt
    10441 ggcgagcagg acggggttgg cgcgcagggg tgcgatgagg atggtggtgg cgagccgtat
    10501 ccgggtggtc acggcggcgg ccgcggacag ggcgatcagt ggttccaggt tgtcgtacac
    10561 cagacggtcg aaagcggcga gtgtggagaa gccgcgtgcc tcggcacgcc gggcccattc
    10621 cagcagctgc gtccgctgca caccgggcag tgtggcgggc aggccgatcc ctatccgcat
    10681 ctcggtctcc tatcgggtgg tcaacggtgc tcggtcgacg gggccgggct gaggtcggcg
    10741 accgccgcgt gctcgcggag cctctcctcg gcggtgtgct cgaccttcgc catcgccacg
    10801 cgcagcaccg ggggcgccat gagcgaggtg atgacggcga cgagcacgac gatcgtgtag
    10861 agcgcggggc tgaggacgcc gagccggagc ccgaccatcg ccacgatgac ttcgatcacc
    10921 ccgcgggcgt tcatgccggc cccgagggcc agcccttccc agtgccccat ccggctcagc
    10981 cgcgcaccca gataggcgcc cgcgaacttg ccgaacacgg ccagcgacag caccacgacg
    11041 gcggtgagca ggaccgcggg gcggcgcagc gcggtgaggt cgacgcgcag tccggcggtg
    11101 gcgaagtaga ggggggcgag cacggccagc acgacggtgg tcagcgcggc acagcgctcg
    11161 ggggtggcga accccgtgct gccgatgacg accccgcaca ggaaggcacc gaagacaccc
    11221 tccaggccgg ccgcctgggt gccggcggcc gcgagcagca gcagcacggt caccgtggcg
    11281 aggaagagac ccggggtgcc ggaccgggtc acggcgcgca gcagggcccg tatcggcggc
    11341 cgcagcagca gggcggcgag caggaccacc ggcacccagg ccaggtgcgc cagcagactg
    11401 tgggccgtca gcgtcgaggt ggccatggcc gagaccgcgg acagcagaat ccagccgatg
    11461 atgtcgtcga tcgcgacggc gcacagcgtc aactggccga cgtcccggtg caggagccgc
    11521 atctcggtga gggtcttggc gatgaccggg atggcgctga cacccatggc gacgccaagg
    11581 aatgcggcga aggttccccg gtcggccgtg tccggcagca gggagccggg gaccaggaag
    11641 ccggcgccca cccccagccc gaggggcagc acgatgccga acagactgat ccgggcggcg
    11701 gacgcaccgc gccggcggac caggcccagg tccagttgca tgccggtcat gccggtcagc
    11761 agcagtacgc cgagctgccc caccgcgtcc agcagatgca tccgggcggg gtccgggggc
    11821 agcagccacg cggacaggcc cggggcgaga tgggcgagca gggagggacc gaggagcacg
    11881 cccgcgcaca actcgccgac cacgggcggc atatggaagt gggcggcgag ccgcccgagc
    11941 agcacggcca ccgccagcag tccgccgagg ttgcacagca gcacgaccgt ggtgtgcgcg
    12001 tcgagcggcg gcacgacggc ggtggcggtc agggacgtca tggtcaggga gctcataggt
    12061 cttcttccgt gaggcgaagg tcggcggcga cggcccgggc cagcgtgcgg gggtcctcga
    12121 ggtggaagaa gtggccgccg cgcaccgccc gcagcacgta cgaccggtcg gtgaaggacc
    12181 gccagccggt catggcgtcc aggccgacca gtgggtcgcg gtcgccggcg aacccgcgca
    12241 gcggcaccgg caacggtggc tgcacggcgg gccggtgcgc ggcgagccag cctagatcgg
    12301 agcgcagcac gcggacgagc cgttcccggg tgcgtgcgtg ggcgagcacc cgggccggtg
    12361 tgccgcccag cgccgcggtc tcccgcacga gatcgctgtc cccggcgtcg agccagcgcc
    12421 ccagccagct catcgggctc agcggcggcg gtgcggcgcc gacatagacc cgggacggca
    12481 gcggcgcacc ggaccggacc agggcttgga cgaccgcgtg cgcgacgacc ccgcccatgc
    12541 tgtgtccgta gagggcgtag ggccggtcgg tgcggcggca cagtgcctcg gccagttcgt
    12601 cggtgctcag gtcgggcggt tcggtgatcc ggttctcccg gcccggaggc tgcacgggct
    12661 ggacgtgcag tcccgcgggg gcgtgacggc gccagcccag atatccggtg gccccggcgc
    12721 cggccggagg caggcagtac aggacggcct cggcgtcggg gccgggaggt ggtccgagga
    12781 accagcggtc cagcgcggct gcggtggcgg acattgggtc agacctccag gtggcgggtg
    12841 aggaagtcgg tgtgcgcgtc gcccgaacgg aagaccgggt ggtccaggac ccgctggtgg
    12901 aacggaacgg tcgtgcgcac ccccgcgccc tcgacccgca cctcgcccag ggcgcgacgc
    12961 atccggttca gggcggcggg gcggtcctgc gcccagacga cgagcttggc gatcagcgag
    13021 tcgtagtggg cggggatcga cgaaccgggc acgcagtggg tgtcgacgcg tactccgggg
    13081 cccgccggca gccggaactc ggtgagcgtg ccgggtgtcg gcgcgaactg ccggtcggga
    13141 tcctcggcgt tgatccggac ctcgacggcg tggccccgca ggttgacgtc ggcctgttcg
    13201 agctccaggg gcgcgcccgc cgcgacgagg atctgctgct ggaccagatc gacaccgcag
    13261 accatctcgg tcaccgggtg ttcgacctgt atccgcgcgt tcatctccat gaaccagaag
    13321 cggccgtcgt cgtcgagcag gaattccatc gttccggctc cgcagtaccc gagcgccttg
    13381 gtgccgagca gggcggcctc gccgatctgg ccgcgcaact ggtcgtcgag cgccggcgag
    13441 ggtgactcct cgatgagctt ctggtgtctg cgctgcaccg aacagtcccg ttcaccgagg
    13501 tgcacggcgt tgccgtgggc gtcggcgagg acctggatct cgatgtgccg ggccaccggc
    13561 aggaagcgtt cgacgtacac gcggctgtca ccgaacaccg cctgggcgtg cgcccgggtg
    13621 gtcagataga cgtgggcgag ctcggctgcg gagcgtgcga cggcgatgcc gcgtccgccg
    13681 cccccggcca aggccttgac gacgaccgga taacccagct ctccggcgac ggccagcgcc
    13741 tcctccggac cggcgacggc ttccgcggtg ccgggcagca gcggcagccc ggcctcggtc
    13801 atcagccggc gggcgctcgc cttgtcaccg acggcgtcca tgacgtccgg cggggggccg
    13861 atgaaggtga tgccgttcga ggcgcagatc tccgcgaagt acgggtcctc ggagaggaat
    13921 ccgtagccgg ggtggatggc gtcggcgccg gccctgagcg ccgcggagac gacgttgggg
    13981 atgtggagat agctgcgccg ggccggtgcc ggtccgatgt gcacggactc gtcggcgagg
    14041 cggacgtgtt cggcgtcggc gtcggcggtc gagtggacgg ccacgctcgg gatgcccagc
    14101 tcgcggcagg cacggacgac cctgaccgcg atctctccgc ggttggcgac gagtatcttc
    14161 cggaacatca cggaatcact cctcgaccgg ttcgaggtcg agcagcggct ggccgtactc
    14221 gaccatgtcg ccgtcggcca ccaagaaggc gatgacgcgg ccggcgagct ccgtcctgac
    14281 cggggtgaac agcttcatcg cctcgatcag ggcgacctgg tcgccgggcc gcaccacggc
    14341 gccgatctcg acgaacgcgg gcgcgtccgg tgtgggccgg ctgtagaagg cgccgaccag
    14401 cggcgcggtg accgcgaggg ccggggcgga ccccaccacg tcggtcgacg ccggccgggc
    14461 cgcgacgggt gccgcggtcc gggccccgcg gttgctccag gtgacgtcca ccgagcactc
    14521 gccgacgctc accgtcagcc gccggatcgt gccgggcagg ccctcgacga tacgttccac
    14581 ggcggtgctc agttcctgta cccgggtgga ttcgcccgga gcgtcaatct cccccatgtc
    14641 caaggccttt cgtgagccgg agtttgggat cgccgaaccg tgcgtagcgc tggtaacgct
    14701 gatcgacgag ctgactcggc tgcagctcgc tcagctcgtc cagggtctgg accagggcgg
    14761 ccttgacccg ctgcgcggtc gcggtgtgct gggtgtgggc cccgtccccc ggctccttga
    14821 ggactccgtc gacgatgccg agccgcagca ggtcgcgtgg ggtcaggcgg agctgttcgg
    14881 cggcccgctg ggcggcggac ctgtcgccga agaggatcgt ggagcagccc tcggggctga
    14941 tgaccgagaa gtaggagttc tccaggatca gcacccggtt gcccaccgcg agcgcgagtg
    15001 ccccgccgct gccgccctct ccggtgacca cgcagacgac gggcaccggt agctcggaca
    15061 tgcgcatgat gcagcgggcg atcgcgtatg cctgtccgcg ttgttcggcc tcgatgcccg
    15121 gataggcacc gggtgtgtcg acgaacgtca ccagtggcag gccgaacctg gccgcgtagt
    15181 ccatcagccg gtgtgccttg tggtagcccc agggctgcgg catgccgaag ttgcgccgga
    15241 ccagctcgcc gacctcatgc cccttctggt ggccgatggc gaccacggtc cggccgtcca
    15301 gccgggccag gccgccgacg atcgccgggt cgtcgccgcc ctgacggtcg ccgtgcagtt
    15361 cgaggaagtc gtcgaagacg taggcgcagt agtcacgcgt ggtcggccgg cccaggtcgc
    15421 gggcgagggc cacgatctcg gcggggtcgc gttcgggcag cagcgccggg tcggtcaccg
    15481 gggtgtcccc ggcgtgcgcg gtgtcgccgg acaccaccgg gcggagaccg ggacgggcgg
    15541 cgagagagtg cagtcgcagc agccgggaga gcaccgtgcg cagttcctcg cgcggcacga
    15601 ccaggtcgat ctggccgttc tcccacagga attcggcggt ctggaagcgg tcgggcaact
    15661 cctggcggat cgtctgccgg atcacctccg ggccggcgaa gccgatccgg gcccccggct
    15721 cggcgatgat gacgtccccc agcatggcga aggaggcgga ggcgccgccg tacgtggggt
    15781 cggtgttgag gttgacgacg aggacgcccg ccgcgtgcag ccgggccatt tcctgactgg
    15841 tcttggccag ttgcatcagc gcgatcgcgc cctcctgcat ccgcgcgccc ccggaggcgg
    15901 acacgatcag cagtggcacc cggtccttca gcgcgtgccg ggcggcacgc gagatcagtt
    15961 cgccgaccgc gccgccgatg ctgccgccga ggaaggcgaa gtccagcgcc gcgatcacga
    16021 tgggcacgcc gtcgatgcgg gcggtcgcgc acagcgcggc ggcggagttg ccgctgcgtc
    16081 ggcggccttc ggcgatgcgc tcggggtacg gcttgctgtc gacgaacccg aggacgtcct
    16141 ccggaaccac ctcctcgccg aaccgcaccc cgctgccgga gtccaccagc aggtcgagcc
    16201 actcccgggc gcgcagccgg aagtggtgcc cgcagtccgg acacaccttc agcaaccggt
    16261 ccagccgccg gcggtagacg agttcgccgc agcccgtgca gcgcacccag tcgtcggtgg
    16321 cgagcggagg ggaggccatg tcacgccgcc tcgacgaggg ccgtcgtacg gcacaggatg
    16381 gtgtccatct cggcgagttc ccggcagacc ttgaaatggt cctggacgcc gggcgagacc
    16441 agcatggcgt cgaagtccgc cttgctgcgc cactgggcgt agttgacgac gtggaccccg
    16501 tccttggtga ggtgcacatt ggcggagacg aatcccggaa gcgcgcggat cacgtccgtg
    16561 gcgccgacga tggcgtcgta gacgcgcgtc tggtgttcgg gagccacctt gaagacgttg
    16621 accagggtgt agtagtcgtc ctgcccggtg atgaccgcca tcgttgacac ctttcacgtg
    16681 gttcggtggt tgtggatgcc gccggtgggg ccggcggtca ggtgcgggtc agtaccagtg
    16741 ccgcgttgaa gccgccgtgt ccccgggcga ccaccaggac ccggcgtacc ggccgggcgc
    16801 ggggatcgcc gaggacgagg tcgatgccgt agtcgtccgg cacctcgccg acgttcgcgg
    16861 tcggtgggat caccccgtcg cgcatcatca gcagggcact gatcacgtcc agcggcccgc
    16921 cgcccgcgta ggtgcggccg atcagcgtct tgggcgcggt gacgggtacg gcccggcggc
    16981 cgaagacctc gacgagggcg gcggcctcct cggcgtcccg gtccggcagt ccggcggcgt
    17041 ccgcgcacac cgcgtcgatc tccgcggggt cggtgccggc gtcccgcagc gccccgcgga
    17101 tggccggggc caggttcggt ccgcgcccgg agtgcggcgg cgggtcgaag gtggccgcgt
    17161 acccggcgac ctcgccgtag accgtgggtg cgccccgctc gcgcgcggcg gaggccggct
    17221 cgaggacgag gagggcgccg ccctcgccgg ggacgtatcc gctcgcccgg cggtcgaagg
    17281 gcaggtacgc ccggtgcggg tcgtcggcct cgctcagcag gccgttgggg atctgcgcgg
    17341 tcagccccca gggggagagc ggggcgtcca ggccgccggc cagggcgacc cggaccgtgc
    17401 cgcgccgcac ctggcggcgg gccgccgcga gcgcgtcgag gccgccggcc tgctcggcca
    17461 ccacgaccga gctgtggccg cgcatcccgt gccggatgga gagctggccg gtgttgacgg
    17521 cgtagaacca ggcgaacgac tggtacgcgc tgacccgttg cggtccctcg ctccacagct
    17581 tctgcagctc gcgttggccg aactcgaagc cgccgcagcc gctggcggtg atgacgccga
    17641 ggtcgtagcg gtcgtaccgg gccgggtcga cccgggcgtc ctccagtgcc tcctcggccg
    17701 ccgcgagggc gtactgggtg acccggtcgg tctgcggcag cagtcggcgc ggtacccgcc
    17761 cgcgggcgtc gaagccacgg atctccccgc cgagacgggt gggatagcgg ctcgcgtcga
    17821 accggccgat cgggacgatg ccggaccgtc cggccagggt cgccgcccag tggcgctcgg
    17881 cgttgtcgcc gttggccgcg agggcgccga tcccggtgat gaccactcgc gtcgcgtcgc
    17941 tcacggtcag acctccggtc gccgcagcac ggccgcgctc tggaagcccc cgaagccact
    18001 gcccacggtg agcgccacat cggtacggca ctccctggcg accagtggga tgtagtccag
    18061 gtcgcactcg ggatcgggct cgtgcaggtt cgcggtgggc ggcagcaggc cgtgctcgac
    18121 ggcgagggcg caggcggcga tctccaggga gccgacggag ccgagcgagt gcccgatcat
    18181 cgacttgatg gaactgatcg ggacgccgtg ggcggccctg ccgagcgcgc gtttgaaggc
    18241 ggccgtctcg tgcaggtcgt tctggcgggt gccggagccg tgggcgttga cgtagtcgat
    18301 gtcgtccggc acgacctggg cctgccacat cgcggcggtg atcgcctcgg ccatctcggt
    18361 gccgtccacg ctcagtcccg tcatgtggta gccgttgcac cgcgtcgcga agccggcgaa
    18421 ctcggcatag gcgtgggcgc cccggcggcg ggcgtgtccg ctctcctcga gcaccatcac
    18481 ggcggcgccc tcgccgagcg cgaacccatt gcgggtgcgg tcgaagggac ggcacgcgcc
    18541 ggccgggtcg tcgttgtcgg gcgaggtggc ccgcagcgcg tcgaagcagg cgtacgtgat
    18601 cggcgacagc ggcgcgtccg aggcgccggt gatcacgatg tcggcggctc cgtcacggat
    18661 cagttcgagg gcgtggccga ccgcgtcgag accggaggtg caaccggtcg acacgacggt
    18721 gctgggaccc tcggcgccgg ccgcccacgc gacctcccgg gccagcgacg aggggacgaa
    18781 gtagtcgaag agctgctcgg cggccagagt gtggtccacc agccagtccc tgccgtgcct
    18841 gctgacggtc gcgtactggc tctccaggcc catggtgcag ccgacggcgg tgcccaggct
    18901 caccccggtc cgcgacgggg acgggggcgc ggcgaccagc ccgctgtcgt ccagcgcctc
    18961 gcgcagcgcg accagcgcga actggatcat gcggtccagg cgtccggcct ggtcctcgga
    19021 gagaccggcg gccaccgggt cgaagtcgac ctcgccggcg atgcgcgacc ggtatccggt
    19081 ggcgtcgaag agggtgacgg cacgcgtcgc ggaccggccg gaagtgatct gttcccagaa
    19141 gggcttggca cccaggccgc ccccgggtgc gacgaccccg aggccggtga tgacggcttt
    19201 gcgcatgtca gctccccacc gacggcggct gggcggacgg ctgcggcacc ggctcgacct
    19261 cgacgtgtcc ctcttccggg ctgggcgcca acggcgcgac ctggaagacc aggaacgccg
    19321 tggaatcccc cacgttctcg tagcggtggt gcgccccctt ggggaccagg accgcctcgt
    19381 gccgctcgac caggatgtcc tcgccgtcga cccgcatgcg cagcgaaccc tcggccagga
    19441 acacgaactc gtcggagtag gggtggtagt gggccgacac gtactcgccc ggttcgaggg
    19501 tcatcgtgcc gaggaagccc gaacgggcgc cgaccgactt ctcggtgagc aggaaccgga
    19561 tgtccgcgcc gagccggcga ctggccggca cgtcccgcat cctgatcttc gacggggtca
    19621 tcgggtcgct ccggtgatgt cggcacgcca gctgtagaac tcctcggccc gggtgtcctt
    19681 cagagtccgg aaggcggggg agtacggcgt gagatgggag ccgagacggt cgcggatctc
    19741 ggcgaaggcg ggatgggcac gcgccgcgaa gatgtgttcc aggagatcgc cctccaactc
    19801 cggccggccc tccaccagat gggcgtagag gccgtggaaa cggaacaggg tccggctcgc
    19861 gagaccgatc tcctcgggca ggccggtgcg gtcgtgggcc gcccaggcct cggcgacggc
    19921 gggggcgtcg tccggtcgca tccggtcgac gaagagaaca cgctgcatga ctactccagg
    19981 gcaaggacgg agaacggggc cgtcgggtcg tcggaacggg caggcacagg agcggggacg
    20041 ggcagggacg agcggagcac gggcggagac ggcagccggt ggcccggcac tcaccggccg
    20101 ggtgcgccgg acggccggga cgagggccgt ggcgggtcgc cgcggtcagt cggggtcgag
    20161 ccgggtgacg atggcggccc ggtcgacctt gccgttcgga ttgagcggga gccgggccca
    20221 gtgcacgacg tcacggggca gcatgtgcgc gggcagacgc tcccggaggg ccgccagcag
    20281 cccgtccgtg tcggcgttcg ccccggtgca gacggcgtgc agggtcacgg gaccggagtc
    20341 cggctcggtc agagccacca cgatcgcgtc ctccacaccg tcctggcgcc gcagttcggc
    20401 ctcgatctcg ccgagctcga cccggtagcc ctgcaccttc acctggtggt cggcccggcc
    20461 gaggtggacc aggacgcggt cggtctcggt gaccaggtcg ccggtgcggt accacagctc
    20521 ggcggcaggc cgcggaccgg cgtcggcggg agtcgcccgc acaccgtcga agcgcaggaa
    20581 ccggtgccgg ttgtgggccg ggtcgagata gccggcgaag cgctggggtc cgcggacgca
    20641 gagctctcca cgcgtcgccg ccgcacccct gtcgtcgatc accaggtgtt cgagaccggg
    20701 atacggcgtc ccgatcggga cggtgccgtt ggcagtccgg ggccagtccc cgggtgcctc
    20761 cgggagcctg aactgggtgc agctcagggt cagttcggtc ggaccgtaca ggttctccag
    20821 aacggacccg ggcgccgcgg cacgccaggc gcgggcctgt tccagggtca gccgctcacc
    20881 gcagaacagg ctccaacgca gccccggcat ccccccctcg ggcagtcggc ccagccgcag
    20941 ggccatcgag atcacggacg gcacggagaa ccagtgggtg atgcgccgcg cggccacgaa
    21001 gcgggcgggg gccaggagtt cgcgccgggt ggggacgacc agcgtggcgc cggagcccca
    21061 cgtggcgaac aggtcgaaga cggagaggtc gaaggtgagg tcgaaggtct gcgagacccg
    21121 ctccccgggc ccgagtccgt agcgcgggat cacatgcccg aggtaggcgt ccacgttgga
    21181 gtgccggatc ggcacccctt tggggacgcc ggtggacccg gaggtgaaga gcgtgtaggc
    21241 gacgtccgcg gcgcgggcgg cacggcccgg tgcctccggt gcgggccgcc cgacccgctc
    21301 cagcagcgcg tcgtcctcgg cgaccaggac cggcacgggg tacgtggccc tctcctgcgc
    21361 caccaccagg tcgacgtcgg cgagcgcggc cacccgtacg cggcgggatc gcgggaacga
    21421 cgggttgagc gggacggccg tggcacccag ccgctgcgcg gccagatagg ccacgtatgc
    21481 ggtgagcgag cggttggcgt ggacaccgac ccgggccggg acggcaccca gggtgcgggt
    21541 gatgtccacg gcgaggtggc ggaccagcag gtccagttca cggtaggaca ggcgcgcgtc
    21601 cgccacctcc agcgcgcagg cgtccgggtg ctgtgccact gagccggtga accagtcgta
    21661 cagcgtacgt tcagacatga cggtccttca gcgcgctccc cgggcggcgg tacgcgccgc
    21721 tgtctcgacc ttctccttga tgaccgccat ctggatcgcg gtgttgtcgt tgatgcgctt
    21781 ggtgatgccg gcgtcgtcga acggtgcgtc cggcccggcc gcgaactcct ggcgccagcg
    21841 catccgcgtc ccgttgccct ccggggtgaa ctcccagttg atgcgcatga attcgaaggg
    21901 cccggtctcc acgcggtggg cggagaccgt gtggttcagg gggtcggtgg tgcgctcgct
    21961 cacccagctc cacaccgagc cgtccgggtc cgggtgcatg gtcagccgga agcggacggt
    22021 gttgccgcgc tccgccagca cctcgacgct cgcgtactcg gtgaacagct ccggccaggt
    22081 gcgcacgtcg ttcgtcagac gccacacaag atcgatgggg gcttcgatgt gtacggagtt
    22141 gtcggtgtcg ctcgccatca gtcctcactc ctcgtcgcgc cgtccaggta ggcggctatc
    22201 tgagtgatcg tcatcgtggg tgcctcttcg ggcatgtcca cgccgtgcgg ttcgaacagt
    22261 tccttctcca gctcgatgac tccgatggag tcgactccga gttcggtgag cgagctgtcg
    22321 cccgcgccgc tgacggtctg ctggtcgagg ccgatgtgct cggtcaggac ggtgcggagt
    22381 ttcgacaggg tggtgctcgt ggtcgccatg ggggtgtcct ccgttcgcag gccggtgctg
    22441 tgtcagaccg gtcggcattc cagcagggtc cagtggtaga tcggctcgga gagcagttcg
    22501 aagcccgccg ccgcgaacag ctcccgccag tcgtccaggt tgcgttcgcg cccgccgtgc
    22561 agcacgagca tgtccaggtc gaggaacttg ccgtggtccc aggcgttgcc cgggtccagg
    22621 atcgagtcca cgaccagcag acgggcggag gagtccggca tgctctcgcg cacaccggtg
    22681 aggatgcggc gggcctcggc gtcgtcgaag tcgtgcagca cggccttgag caggtagccg
    22741 tcgcagccct cgggcagcgg gtccttcagc aggtcgccgg cccggatctc ggcccggtcg
    22801 gcgactcctt cctcggcgag gaccgaggct gccttcttcg cgacgtgcgg gaggtcgacc
    22861 agcacaccgg tggtgtcggg gtgccgtttg aggatctggg ccaggaagaa gccgtctcca
    22921 ccgccgaggt cggcgatgcg gcggaaccgg ccgaggtccc actggttgag ctcctcggcc
    22981 gcgaactgtc ggctccagtg cgacatgaac ccgtcgtaga agtcgtcgat gccggggttt
    23041 tgctccaggt actcgatgaa cgtgctgccg aacgcctggc ggaagacggg ctcgccggtg
    23101 cggacgctgt gcaggaagga ggcgtacggc cgctcggtca gctccatgcg gttgtacctg
    23161 accaggggca ggactccgtc ggggttgtcc gagcgcagcc cgtcggccag cggggtcgac
    23221 gagaagacgt gcgcggggcc ctcggcgaag atgccgacgg aggcggcgca gcgcagcacg
    23281 cggtagaggg cgtcggggtg ggctccggcc cgctcggcga gctcctcgac gggcagcggc
    23341 ccgggcgcca ggtggtcggc cacctccagc tccaccagga cctcgacgat ctgcgacagc
    23401 cggccggagc aggcgagcag cagcaggtgc tgcgcgtgca gatcgtcggg aaccgggttc
    23461 cgcggcgcgg tctcggcgtt ggcttccatg gtgctcactc ctcagctgtc ggtcttggca
    23521 cggcttttgc ggtgtggcta ccggtcgcgg atgaccccgt tgaccgcttc caggacttcg
    23581 cggggggtgc gtccgcggct catggcctcg tcggccagtt cgatgccata gcggtgccgg
    23641 atttcgctca gcacttccag cagggccacc gagtcgtatc ccaggtgttc gaagaccaca
    23701 tcgagtacgt cggcgttcag ttcccgctcc tcgggttctc ccgcgcgttc ccgggtgagt
    23761 tcgaagagtt cttccacggt gatttcccgc actgttatcg gactccttcc cgtgtctttc
    23821 cgtgccgtgt cagtcgacgt cgaggtcgaa gaccggctgc agggagttca gaccggagat
    23881 gagggtcacg aagtccttgc gggggaagaa gagctgcccg ggatccacca gtgcctgcgc
    23941 gtactggtag taggcgtcgc ggtccagccc gacgtcgtag aaatagcgga cgaacgacag
    24001 gatcgtcccg aggaattcgc ggtacgactt gtcgtagcgg gcctggacgg tggactcgcg
    24061 ctccgggtcc ttgaggatga ccgggatggc ctcggccgcg gcccggccgg ccagcatggc
    24121 cagggtgacc ccggtggaga acagcgggtc cacgaagccg gccgcgtcac cgaccagcat
    24181 ccacccgggc ccggcgaact cccggcagac gtaggaccag tcgcgcgccg tgcggaaggc
    24241 gtcggtgcgc ttggcccgct tcatgtactg cttgaggtga accgactcct cgaccttggc
    24301 ctcgaagagg gccggcagtt ccaggccggt ggcggccgcg tcctccgcgg cggtgacgaa
    24361 gccgacgctg tgggtgccgt cgtgcagcgg gatgtaccag aaccagccgc cgggtacgtg
    24421 ctcgacgaag atgttgcccg tctcgtcgcc cgctagtggc tcgccgtcct ggtagtagct
    24481 ccagacggcg acgttgcgca gatcgtcctg ccagtccacg ccgccgagcg tgcgcccgag
    24541 cacccgggcc tgcccggagg cgtcgaccac catgcgggcc cgcgcctcgc cctcctcccc
    24601 gccgcgcacg acgtaccgca cgccgacgac ccggccgttg tcgaccacgg cctccttgac
    24661 cgtggcctgc tccagtacgt gggcgccgag ctcccgggcg cgggtgagca ccagggcgtc
    24721 gaagtcggcc ctccgcacgt tgtaggcgtg cgggaattcc ggctttccct ccgcgaaagc
    24781 gaagcgccag cggccgtcac ggccccacac cagactgccg ccgtatttct cgacgaatcc
    24841 cagggccgcc acccgctcgc gaattccgag ttcttcgagg acccccatgc agccggtgat
    24901 cagggattct ccgatgtgat agcgcggaaa tttctcgcgc tccagcagga gtacgtcatg
    24961 accgcttcgg gcgaggagtc cggccgtcgc ggaacccgcc ggacccccgc cgatgacgat
    25021 gacgtcgtat tcggtggtcc gtacgtggtg ttcgggcatc gctgcatccc cttctcgcga
    25081 actcgatcac gctttccgag aaggttgacg gacgtctcta gaatcccgct gaaggtttca
    25141 taagggggag attcccacca cataaatgaa ccgccgcacc ggcgcggcgg ttcagcagag
    25201 cagggcggtt ctgggtggtg gctcaggtgg cggcgccgac cgtccgggtc ggccagtacg
    25261 cggatgtggt cgctgaacga gaaccctcgg tcacgtgcat cccccggtgt cccccgcgct
    25321 ccgggagcgg accgcgaccg ctctcttcca tgaagtagat ccgcacgacg tcggggatgc
    25381 ggaagagcat gtccccgtcg ccgttctccc cgaccggcag cacgagccgt atctgggagg
    25441 cctcgagcag tgcgacctcc gcctggaccg tgctgcagcg gaggatgtcc gccgcctcgc
    25501 gggaggtgaa ggtcgtcgac gtctcccggc tgagtggggc gaggcagccc cgggtcgccg
    25561 gtgtcagctg ccggcggccg cgggccagcc gagcccgtag atcgaggtcg ccggagcgca
    25621 gctcggacag ccggcgatgc cggtcgacca gccgggccgc gcaggcctcg agagagacat
    25681 gggtcggcgc gcagagccgg gagccgatgg cacgcagcgc gagcggcagg cactcgcatt
    25741 tgtcgacgat ggtgcgcagg gtcggcaggt caccgtcgtt ccaccgccgg ccgacgatcc
    25801 gtccgaggag ttccacggcc tcgttggggg cgaggggatc gacctccacc acgcgggctc
    25861 cgctcagccc gggcagcgac tggcagctgg acaccaggac cgcgcagtgc gcaccgcccg
    25921 ggaccagtgg tcgtgcctcc cgttcggaca gggcgtcgtc gagcaccatc agcacgcccc
    25981 ggtccgcgct ccagctgcgg aagagctgac tgcgcgcctc cagggtgtcc ggtatctgct
    26041 cgggggtgaa gccgagagag cggaggaagt ccccgagcag ccgacgcgga tcggcgggtt
    26101 cgccgttgtc gtcggtgagc gaggcgtaga actggccgtc cgggaagcgc cgcttgagcc
    26161 ggtgggcgag ccgtaccgcg aacgcggtct tgcccacccc cgtgcggccg gtgagcacgg
    26221 tgatgttggt ggccgtgtcg tcgacacagt ccagcaccag ccgttcggtc cgggccagca
    26281 gagccgtgcg tccggtgaag tccggtatgt cggccgggag ttgcgccgga tgcacatgga
    26341 cggcggcgga ggaggcccgg ggggcgccga ggaactcgtc gacggagtcg tcggcggcga
    26401 gcagcgcgcg gtggagccgc tgggtggcgg cggtgggttc cacccccagg gcctcgacca
    26461 ggttggtgcg cagcctggcg taggtgtcca gcgactcgtg gcgccggccg agccggtaca
    26521 gcgcgagcat cagcttcgcc tggaagccct cgtgcaacgg gtgggctatg gtcagcgcct
    26581 tcagttcccg gacgacctcc tgatgctggc cgagttccgt cttggcgtcc acgcgcagtt
    26641 cgatcgcctg gagacgagcc tcctccagtt gggtcgcgta cgcctccagg cgggggccca
    26701 tggtcacgtc ggcgaacgcc gaggagcgcc acagcgacag tccggcgtgc aatgcccggg
    26761 cactccgctc gaagtcgccc gcctcgaaag cgagccggcc ctcacggaag cagcgctcga
    26821 agacatgcga atcgatggac tcgggaagca cgttgagccg gtagccggac gtctcggtga
    26881 ccagggaggg cactttctcc ttggcgaact tgcgtgattc caggatcttg cggagctgat
    26941 agacgtaggt ctggatggtg gccacgacgg tggtcggggg ctcgtccggc cagagttcgt
    27001 cgatgagtct gctgacgggc acggtctggt tattgagagt cagcaggagt gagagaatcg
    27061 tgcgtaattt tggcgccagc ggaacaatcc tgccgtcacc gctttcgatc tctagatttc
    27121 ccaggagtcg gaactgcata acaccgccct actgatgtag gtgtttggtt gccgcaggtc
    27181 atggctcatt cacccggtgg ccggtcatca atacggccgg aatgcgggcc gttcggcggg
    27241 cgtctctcag cgaggcgccc ctagcactgt tcgggtgcgt atagcatagg catgcgaaga
    27301 gagcgtccag gtaaagttaa agcaaaacaa tcccgtgatt atccggactc ccggactcca
    27361 ccagctaaag tgctccaccc cgcacgcggg ccgcgtgcgg ggtggtgaaa tacttccaat
    27421 ttaaataaag atcgccggat ttaattcgga cgtgccgctt accagcacca ggcctcgggc
    27481 gcgggaccgc ccttgccgac aggcgggaac agctcgtcga ggcgcgtcag cacctcctcc
    27541 ggcagtttca ggcaggcggc ccacagcgcg tcgtcgagct gctcgacggt ccgcgggccg
    27601 atcacgggcg cggtgacacc gggccgggac atcacccagg cgagccccac tcgggccggc
    27661 gactccccga gttcggcgca cagcttctcg tacgcggcca gggcggaccg gtggccgtcg
    27721 agggcctcca tcgcccggcc ctgggcggtc ttcaccgcgg tgccgtcggc cagcttgcgc
    27781 agagcgccgc cgagcagccc gccgtgcagt ggggaccacg ccagcaccgc gatgccgtag
    27841 gcgcgcgccg cgggaatgag ctccagttcc acgtgccggg tcaccaggtt gtagacgcac
    27901 tgttccgaga cgacaccgag gaagtggcgg cggttcgcgc tctcctgggc cgccgccagg
    27961 tgccatccgg cgaagttgga ggtgccgaca tagcgcacct tgccctgggc cacgaggagt
    28021 tccatggcct gccagatctc ctcccagggc gcccgccggt cgacgtggtg catctggtag
    28081 aggtcgatcc agtccgtgcg cagccgacgg agcgagtcct cgcaggcggc cacgatgtgc
    28141 cgggccgaga gccctccgtc gttgggtccg tcccccatgg cgccgaagac cttggtgccc
    28201 agcaccacac gctcgcgccg gccgccgccc tgtgcgaacc atcggccgat gagctcctcg
    28261 gtgtaaccgc ggtgcacctg ccagccgtag gtgtcggcgg tgtcgacgaa gttgacgccg
    28321 ttgtcgaggg cgtggtccat cagggcgtgg ccctcgtcct ccgtggtgcg cacgcccaga
    28381 ttgagcgtgc ccagacaagg cgtgctcacc tggagcgcgg tacggccgag ggacttgtac
    28441 accacgtcgg tcctcgcggt catgggcggt gccctcctcg gtccgggttc ggttccactc
    28501 cgaccggcga gccggagtcc gccgtcagac aggcgtcgag gaccgtgcgg tagtagtcgc
    28561 cggggaaggg cggcacaccc tcgccaccgc ccagcagccg gcgcagcctg tccaccgaca
    28621 ccggagtctg cggtcccgcg gcgcgcacgt actcccgacg ggcccgcaca ccgatgcggc
    28681 cctccagatg ggtgacgatc tcctccacgg acaccgcggt gccggaggcg acgttcacga
    28741 cgtcgttgac cacccccgcg ctcagcaggc gctcgacgag tccgaccgcg tgggcgaccg
    28801 cgatgaggtc gcggcacgcg ccccgctgga tcagcacccg acccgccacc acctgccgca
    28861 ccaacgcggg cacgagctga tgcgggcgct ggccgggtcc cgccgcatgg ccgagccgca
    28921 gaatcaggtg gcggggcgcc gacgccttca ggacgccttc catcgcgagc ttgtgccggc
    28981 cgaacgccga acccggcagt acggggccgt cctcgcgacc ggggccttcg gcaccgccgt
    29041 acatgctcgc cgacgcggtc gagaagtaca gcagcagccg gccgtcggcg cggcaccgac
    29101 gcacccacgc gtacagcgcg gcggcctcgc ggtcgaactc cgcggcgtcc gtggcccgtg
    29161 tgctcgacgg cccggccgcg aaggcgacga cctcgtcgtg cgcctcggtc agcggggcga
    29221 gatggcgggc caggaacccg cttccgacga tctccatcag tgggccgccc gcgcggtttc
    29281 cggcgcgaag cccgcggggt ccgccgcgaa ccgggtcagg acgggcacca gatccgcggg
    29341 cgtgggcagt gaacgcagct gatcccgtaa ccgcaccgcg ttcttcgcgt acccggggtc
    29401 ggcgagcagc gcgtcgagtt cccgccgtac cgactgcggc gtcagctcct gcccgaggac
    29461 gaaccgcccg gccccggtgc cggccagctg ctcggcgtcc gtgcgctggt cgaagacctg
    29521 cggtacgacc agctgaggca ctccggcgtg tgcggcggtc agtgtcgtac cggcgccccc
    29581 ctggtggatg aaggccgaac agctcggcat cagcgcggag atggcgagag actcggccac
    29641 ccggacattg gccgggaggt caccgagcag cggccgctgg tccggggtcg cggccaccac
    29701 gatctcggcg tcgtagtccg ccagcccctc aaggatgccc ggcaccagat agtggtcggg
    29761 tccgaagaac cgagtggtcg acgtgcccca gcacacgcac acccgccggg tggcccgcac
    29821 cggttcgagc agccagtccg gcaggactcc gccgagaccg ttgtacggca cgtaccgcat
    29881 cggaagccgc ggggactcgt tggcgatctg gaggtccggc gggcagatgt cgatggtcca
    29941 gggcgccaga tgggcggccg gacgctgacc ggccctggcg tagaggtcga ggagttcctg
    30001 ggggcgcagc cgctcctcga ggtcgggcgg ctgggtcccg aggatgtcga ggccccaggg
    30061 catccgtacg tggggcacgc cgcaggcctg ggcgacgacc ggagcggcga aggtgagcgc
    30121 gtcccagacg aggaggtcgg gctgccagcg ccgggcgatc cggagcaggt cgtcgagcat
    30181 gagctcggcg atgcggcaga agaagccgat gaagtgcctg cgtttgcgga tcgcggcctc
    30241 gtcccaggtc agcggggcgc tgcggggatt ggtccgctga tcggccatca gccaggggtt
    30301 gccctggaac tccccgatca gatcgaagtc ctcgccggcc ggtatcggga cgaggccgga
    30361 gcgcaggacc gtgtccgcga gggcgggctg actcgcgacc agcacctcgt ggtccgcgga
    30421 gtcgaacgcg cgggccagcg gcaccatggg gaagtagtgg gtggcccagg cccaggttgc
    30481 gaagagtatg cgcatcatca cgtccagctg agtgggggga gggggatggt cgcgcctggt
    30541 caatcgcacc ggccggcgtc tccgcctagc acccgtgtcg tacgaccggg ctcgtggcag
    30601 accggaccac tgtgccgccc gcggttgggg attccctgaa cgaacgctga aggccccggc
    30661 agcaccgggg ccggcgtccc cgacggcctc gcaccgactc cgagtcggcc ccggccccgg
    30721 cgccatcggc gtcggtgcag ggccggtcag accagttctg tctccacggt cacgttgccg
    30781 cggatcgcct tggagtaggg gcaggcctgg tgggcctcct cggcgagttt tcgggcctcc
    30841 tccagccgtg cgcccggtac gtccaccgtc aggtgcacgc tcagccggaa gtcccagcct
    30901 tcctggagga gcgtgacgcg cccggtcacc tgggagccct cgacgtcggc cttggcccgg
    30961 cgcgccacca tccgcagcgc gttgtggaag caggccgcgt agccggccgc gaacagctcc
    31021 tcggggttgc tgccgcggcc ggagccgccg agggccggcg gcagtgcgag gtcgaggacg
    31081 agaccgtcgt ccacggtccg cacccgcccg gcacggccgt cgcccgtcgc gatcgcctca
    31141 gccgtgtaca ccgctttttc cgtcattgct cgcctccggg agtatcgaca cgcgcagcgg
    31201 aatgatgcgg ccagaattcc cagagaattc ggaccggccc ccatcatgcc gccggaaacg
    31261 ccgacacacc gcaaaaagcg atccgatccg gcaccatacg gccacccccg gcaccgctga
    31321 catggccgtt caccgattct tgagagcccc aagaggactt ccgcgcaacc tggttcgcag
    31381 ccgggcattc cctcggtcgg aaacggcatt cagtctgagc cacggatagg aaactccatg
    31441 ccagatgtcg aggttcccgt actgatagtc ggcggcggat tgtccggact ggcgtccgcc
    31501 ctctttctgc ggcagcacgg aatcgactgc cgtctcgtcg aacgcaatac gacgacatcc
    31561 cagctcttgc gctcgacgca tgtcagtcca cggacgatgg aactcttccg cacggtggga
    31621 atccagcagg ccgtgtggga cgtggcggaa aaggtggtcc tcggcaaata ctggtccgag
    31681 acggacctgc cgccccgtca gctgcccagg gccattctgc gcgcgaactc cctggccgac
    31741 gtggtcgccg gcaacgtcgt ggtgatggag gagggcgcca acctcttcac caacgtcggc
    31801 ccggtggaac cggtctggtg cggccaggac cgcgtcgagc ccatcatgct ccgcgaggcg
    31861 cgccggcgcg gcgcgcacat cgacttcaac accgagatgc tctcgttcac ggcggacgcc
    31921 gagggagtca gcgcgcgggt ccgcgaccgc ggcaccggcg aggagacgag cgtacgggcc
    31981 aagtacctga tcggcgccga cggcgcgggc gggaagatcc gcaccgaagt cggcatcgaa
    32041 cgccgcggca acggcacggt cggccacgtg ctcaacgtcc tcttcaaggc cgacctggac
    32101 gggatcctgg gcggccggcg cttcctgatc ctgtatctgt cgcaccccga agccgccggc
    32161 atgctcttca aactggacga cgagcgctgg atcttcggct ggttctgcgg ccccgagcag
    32221 atcgaggagg gccgggtcac ggacgccgag tgcgtcgacc tgatccgcaa ggcgaccggc
    32281 gagccgcagc tctccgtcga catccacatg accatgggct ggtggatggc ccacgagatt
    32341 gtcgacagct accgctccga ccgggtcttt ctcaccggcg acgcctgcca tgtgctgccg
    32401 cccaccggag ggttcggggc caacgcgggc atccaggacg ccaacaacct ggcgtggaag
    32461 ctcgccggag tgctgaacgg ctgggccgac gagaagctcc tggacagcta cgaggcggag
    32521 cgtcggccgg tgggccgggc aacggccgac caggcgtgga tgcggcacac ccagtggagc
    32581 gaccccggcg ccgcgaaccg acacgaccag cgtgaccaga cggtcgtcac caccgcctac
    32641 cgctactcct ccgacgccgt cgtcggcgcc cgccacgacg aggtgttcgg tcatgacctc
    32701 accatcgacg gccgccccgg tatgcgtgtg ccccatgtgt gggtgacctc cggcggcgaa
    32761 caggtctcca cggtcgatct ggccggtacc ggcttcgcgc tgctcgccgc ggccgacggc
    32821 gcccgatggg ccggcgccgc ggagacggtc gctcagcgcc tcggcgtccc gctgaccgcc
    32881 cgtcgcgtgg ccccggacgg cgatctcacc gccccgcgcg gagcgctggc atcggtgtgc
    32941 ggcatcgagg agaccggtgc cgtgctggtc cggccggacg gattcgtggg ctggcggagc
    33001 cccggcctgc cggccgaccc caccgccgaa ctccacgacg ccctcgcccg catcgtcggc
    33061 cgccagacct gaacccgcac tcgctgtccc acctttgaga ggaagaaacc accatggcga
    33121 cgatctcggc cgagaaggac tacttcacca ccatcaacgt cttcaccacg acgcccgaac
    33181 accagcagaa ggtcctggag atcatctcgg gcgccgagga gaagatgcgc gacttccccg
    33241 ggttcgtctc ggcgagcatc cacgtcagcc acgacgggac ccaggtcatc ggttacgcgc
    33301 agtgggcgaa gaaggaggac ttcgacggca tgcgcgcccg ggccgacctt cagcagcatt
    33361 tccaggccgt acgcaagctg gtcagctcgg tcgacccgat cgccgcccgc gtcacctaca
    33421 cccacgacgg cacctgatac gcgaaggagc tagacccatg gcacggattt ccgtcaagga
    33481 cgagtacttc accacgatca acgtcttcag caccacgccc gagcatcaga agcgcctggc
    33541 cgagatcgtc gtcgagggcg ccgaggcgat gaagtcccac cccgggttcg tctcggcgag
    33601 catccacctc agctacgacg gcacccgcgt ggtcggctac gcccagtggg cttccgagga
    33661 cgacttccac gggatgcgcg cccgcgccga cctccagggc cacttcgaag aagtgcacga
    33721 gctcggaacc atcgagtcca tcgcctgccg cgtggcctac accagcgacg aggactgaca
    33781 agacacccag agcactcaac acaccagcga cgaggggtcc ttccatgtac gacgcgctgc
    33841 tcgccgagac cgtgcggttc cacggtgccg gcggagacga gatcgagggt tatctggcac
    33901 gcccgttggc gccgggtccg ttcggcgggg tcgtggtgat ccatcacatg cccggctacg
    33961 acgaggccac gaagcagatc acccggaagt tcgccgcgcg gggtttcgcc gccctgtgcc
    34021 cgaacctcta ctaccgcgag gcgcccggcg ccgacccgca cgacgccgcc gcggcggccc
    34081 gggccaacgg cggggtaccc gacgaccgcc tggtcggcga tgccgagggc gcgatcgcgg
    34141 tactgcgctc gctgaccaac gccaacggca aggtcggtgt catcggctac tgctccggcg
    34201 gacgccagtc cttcctcgcg gcgtgcagcc tgccgctgga cgcggccgtg gactgctacg
    34261 gcgcgttcgt cgtcggtcgg ccgcccgagg gcatgcccct gcagatagag ccgatcgccc
    34321 atctcaccaa ggacctgtcc ggcccgctgc tcggactgtt cggcgccgag gacacgacgc
    34381 cctcgccggc cgagacggcg gagctggaga ccgaactgaa gcggcacggc aagaccttcg
    34441 agttccacac ctacgagaac gccggccacg gcttcttcga cgtcgaccgc aagacgtacc
    34501 gcccgaaggc cgccaccgag ggctggcaga aggtgttcga cttcttcggc cgccacctgg
    34561 cctcctgaaa tccgccgccc tttccagcga aggagacccc ggccatgtgc acctacatca
    34621 cggagaaact ggccgcctcg ggcagtgcca agggcgccgg cggatggttc gacctgacgg
    34681 agatcaccgt ctacttcgac cacccgcagc acgcccagga ggcccacaca ctcaacatcg
    34741 acttcctcga tccgacgcag ggtgcctcgg cacgcgtcgc cgtcgaactg accgccgaca
    34801 ccgctctcgc actggcggag gccgtgcgtt ccatcctggc ctcggtcccc gccgggctgc
    34861 tgccggaacc ggcgggtcag gcatgagcac cgccctgatg cgggccgtgg ggttcaccgc
    34921 gttcggcggg ccggaggtgg tgtccgtcgc cgaggtcccg gtccccgaac ccggcccggg
    34981 ccaggtcctg gtgcgcgtgt ccgccgcccc cctgcatttc ttcgaccggg ccgcccgctc
    35041 cggcgcgctg cgctcgatgc tggcggaggg gccgcggtac gtcctgggct gggacatgtg
    35101 cggaacggtc cacacggtcg gccccggagt ggtggccttc gccccgggcg acccggttgt
    35161 cggaatggtc gactggctca ccacccggac cgggacccag gccgagtacg cggtgctcga
    35221 cgcgtcggcg ctggccccgg ccccggccgg cacgacgccc gcggcagcgt cgacgctgcc
    35281 gctgaacgcc ctgaccgcca cccaggccct ggatctcctg cgtctcgacg caggccggac
    35341 cctcgcggtc accggggccg ggggagcggt cggcggctac gtggtcgagc tggccaagga
    35401 ccgcggcctg cgggtcgtcg ccctgtccgc atcgcgcgac gagggctttc tgacgggact
    35461 cggcgcggtg ttcgtcccgc ggtcggacga cccggcgggg gcgctgctcg cggctgcgcc
    35521 cgagggagtg gacgggctgg tggacggcgc ctcgctgggc gaccgggtgc tgcccgcggt
    35581 ccgcgacggg ggcggcttcg tcgccgtacg gccgccggcg acccccgaac cacagcgcgg
    35641 catcaggacc atgcccgtca tcacccgcgg cgacggcgca cagctgcgct cactggtgga
    35701 cctcgtggac aagggccggc tgacgctgcg cgtggcccgc accttcgcct acgaggaggc
    35761 ccacctggcc catgagcagc tggaccgggg cgggcaacgg ggccgcctgg tgctgctgcc
    35821 ctgacaacgg cgcgcggcgc ggccggacaa gaaccgaagg agacccgaga tgcagatagg
    35881 gatcggactg ccgtccaaca tccccggtgt gcggcggacg caactgctgg agtgggcccg
    35941 gcgtgcggag gcacgcggct tctccacact ggccgccaac gaccgtctgg tgtacgacaa
    36001 cctggaacca ctgatcgccc tgtccgcggc cgccgccgtg accacccgga tacggctcgc
    36061 caccaccatc ctcatcgcac ccctgcgcgc caaccccgtc ctgctcgcca aacaggccgc
    36121 ctccctcaac cgcctcgccg acggccgcct caccctcggc ctcgcccccg gcggacgaca
    36181 ggacgacttc accaccagcg acctcgactt ccacacccgc ggccacaccc tcgaccacca
    36241 cctcacccgc ctccacgaca cctggaacaa ccccgacatc ggaccccacc acaccacccc
    36301 ccgcctcctc atcggcggct tcacccccac ctccttcacc cgcgccgcca cccacgccga
    36361 cggctggatc gccggcggcg gcgaccccga cttcttccgc cactgcgccc aacaagccca
    36421 caccgcctgg cacaccgccc accgcaccga caccccccac ctcaccgcca cctcgcactt
    36481 cgtgatcggc gccgaggccg aggcacgtgc gcgccgattc ctgctcgact acttcgcctt
    36541 cgccgggccg cacgcgcggg agatcgtcga cagctcgctc aaggtcgacg aggccgacat
    36601 caaggccacc gtcgacgcgt gcgccaacgc gggcgcggac gagctgatcc tcttctcggt
    36661 cgaccccgac cccgaccagg tcgaccgcct ggccgacatc gtcctgtgag cgtccgtccc
    36721 aaggagggca agcatggctg acacgagcac cgccaccgca cagcaggccg cacaggagtt
    36781 acgggacgcg cttcaggccg gattcaccgc gcaactgctg cgggccttcg tccggctggg
    36841 catcgccgac ctgctggcgg acggcccccg cgacctcccc acgctcacga aggcgctcgg
    36901 cgcgcatccg ggcgcgctcg ccggattcct cggtgcctgc gcgggggagg ggctcgtgga
    36961 aggcgaagcc gacgggcgga tcacggtgac cgaacgcggg ctgctgctcc gcccgtccgg
    37021 ctcgctcggc cagcaggcct tgtgggtcgc cggccccggc gcctcacgga cgtacgaaca
    37081 catcacggag gtggtgcgca cgggcaagtc aggcggcgag gcggccggtc agcacctcta
    37141 cgactactac gccgcccact tggaggaggc gaccgcctac gaagaggtga tgtcggaact
    37201 caccgagggc tgcatcgacg ccctgctgga ggcctacgac ttcaccgcac accggcggat
    37261 cgtcgacgtc ggcggcggcc ggggaaccct gctcgcccgg gtcctggaac gggcgccgga
    37321 ggccacggga ctgctgtacg acgcccccta cgtcgtggac atggcgcgcg gtgcccagaa
    37381 ggcacggacg gagggcggtg aggacggtcg cctggagttc gcggccggtg acttcctgga
    37441 gtcggtgccc ggaggcggcg acctctatgt gatcaagagc attctgtgcg actggggtga
    37501 cgaggaggcc gcccgcctgt tgcgtaacgt gcacgaggcc gcacccgagg gctccgaact
    37561 gctgatcgtg gactggttcc gccccgagcc ccgcgacggt gccgcacagg ggctgtcgtc
    37621 cggcggattc ttcatctgga ccctcctggg cgggcgcctg cgtaccgcga ccgagatgga
    37681 ggacctggtc cgcaccgcgg gcttcaagat cacccgcagg gaaccggact tcgccccggg
    37741 tttcttctcc tggaacttcc tggccgcgac ccgcgactga
//
