BGC0001922: isoindolinomycin biosynthetic gene cluster from Streptomyces sp. SoC090715LN-16
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Location: 1 - 37,780 nt. (total: 37,780 nt).
This entry is originally from NCBI GenBank LC386909.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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General
Compounds
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Biosynthesis
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KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001922
Short description isoindolinomycin biosynthetic gene cluster from Streptomyces sp. SoC090715LN-16
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
LC386909.1
via
Compounds
  • isoindolinomycin
Species Streptomyces sp. SoC090715LN-16 [taxonomy]
References
Chemical products information
isoindolinomycin Evidence:
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C24H26N1O8Cl1
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BBE36449.1
  • idmB1
 1 - 333 (+) hypothetical protein
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    • BBE36450.1
    • idmB2
    		 519 - 1943 (+) transporter
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      • BBE36451.1
      • idmB3
      		 2006 - 3085 (+) aminotransferase
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        • BBE36452.1
        • idmB4
        		 3103 - 4119 (-) methyltransferase
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          • BBE36453.1
          • idmB5
          		 4227 - 5009 (+) dehydrogenase
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            • BBE36454.1
            • idmB6
            		 5059 - 5790 (-) regulatory protein
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              • BBE36455.1
              • idmB7
              		 5868 - 7226 (-) oxidase
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                • BBE36456.1
                • idmB8
                		 7265 - 8671 (-) dTDP-2,3-dehydratase
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                  • BBE36457.1
                  • idmB9
                  		 8774 - 9847 (-) dTDP-1-glucose synthase
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                    • BBE36458.1
                    • idmB10
                    		 9844 - 10680 (-) monooxygenase
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                      • BBE36459.1
                      • idmB11
                      		 10701 - 12056 (-) Na:H Exchanger
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                        • BBE36460.1
                        • idmB12
                        		 12053 - 12814 (-) thioesterase
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                          • BBE36461.1
                          • idmB13
                          		 12819 - 14168 (-) pyruvate carboxylase
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                            • BBE36462.1
                            • idmB14
                            		 14176 - 14637 (-) biotin carboxyl carrier
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                              • BBE36463.1
                              • idmB15
                              		 14624 - 16339 (-) acetyl-CoA carboxylase
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                                • BBE36464.1
                                • idmB16
                                		 16341 - 16661 (-) monooxygenase
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                                  • BBE36465.1
                                  • idmB17
                                  		 16718 - 17944 (-) beta-ketoacyl synthase
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                                    • BBE36466.1
                                    • idmB18
                                    		 17947 - 19206 (-) beta-ketoacyl synthase
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                                      • BBE36467.1
                                      • idmB19
                                      		 19208 - 19600 (-) polyketide cyclase
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                                        • BBE36468.1
                                        • idmB20
                                        		 19618 - 19968 (-) polyketide cyclase
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                                          • BBE36469.1
                                          • idmB21
                                          		 20146 - 21678 (-) amino acid adenylation domain-containing protein
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                                            • BBE36470.1
                                            • idmB22
                                            		 21688 - 22158 (-) polyketide cyclase
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                                              • BBE36471.1
                                              • idmB23
                                              		 22158 - 22409 (-) acyl carrier protein
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                                                • BBE36472.1
                                                • idmB24
                                                		 22443 - 23489 (-) methyltransferase
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                                                  • BBE36473.1
                                                  • idmB25
                                                  		 23538 - 23792 (-) acyl carrier protein
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                                                    • BBE36474.1
                                                    • idmB26
                                                    		 23830 - 25059 (-) tryptophan halogenase
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                                                      • BBE36475.1
                                                      • idmB27
                                                      		 25223 - 27139 (-) regulatory protein
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                                                        • BBE36476.1
                                                        • idmB28
                                                        		 27459 - 28463 (-) dTDP-2,3-ketoreductase
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                                                          • BBE36477.1
                                                          • idmB29
                                                          		 28460 - 29257 (-) dTDP-4-ketoreductase
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                                                            • BBE36478.1
                                                            • idmB30
                                                            		 29257 - 30495 (-) glycosyl transferase
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                                                              • BBE36479.1
                                                              • idmB31
                                                              		 30747 - 31166 (-) hypothetical protein
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                                                                • BBE36480.1
                                                                • idmB32
                                                                		 31597 - 33072 (+) dioxygenase
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                                                                  • BBE36481.1
                                                                  • idmB33
                                                                  		 33114 - 33437 (+) antibiotic biosynthesis monooxygenase
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                                                                    • BBE36482.1
                                                                    • idmB34
                                                                    		 33458 - 33778 (+) antibiotic biosynthesis monooxygenase
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                                                                      • BBE36483.1
                                                                      • idmB35
                                                                      		 33825 - 34568 (+) abhydrolase
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                                                                        • BBE36484.1
                                                                        • idmB36
                                                                        		 34605 - 34886 (+) hypothetical protein
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                                                                          • BBE36485.1
                                                                          • idmB37
                                                                          		 34883 - 35824 (+) quinone reductase
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                                                                            • BBE36486.1
                                                                            • idmB38
                                                                            		 35870 - 36709 (+) hypothetical protein
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                                                                              • BBE36487.1
                                                                              • idmB39
                                                                              		 36734 - 37780 (+) methyltransferase
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                                                                                Biosynthesis information

                                                                                No biosynthesis information available for this record.

                                                                                Annotation changelog

                                                                                Entry version: 4

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2024-03-19
                                                                                MIBiG v4 annotathon
                                                                                • (ID: UOPRUH5Q7GYGWE2YOK43UGOW)
                                                                                • (ID: HSOJFFPY5IUT4HBQLSN7DGJX)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 3

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2022-10-07
                                                                                Update chemical activity to schema version 2.11
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 2

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2022-09-15
                                                                                Updated bioactivity data
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                2022-09-15
                                                                                Added AMP-binding domain substrate specificities
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 1

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2019-10-16
                                                                                Submitted
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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