LOCUS       BGC0001925             20488 bp    DNA     linear   BCT 19-JAN-2019
DEFINITION  Streptomyces sp. NCIMB 40513 DNA, SB-203208 biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0001925
VERSION     BGC0001925
KEYWORDS    .
SOURCE      Streptomyces sp
  ORGANISM  Streptomyces sp.
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 05:24:31
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..3102
                     /gene="sbzA"
     CDS             1..3102
                     /codon_start=1
                     /gene="sbzA"
                     /product="Ile-tRNA synthetase like transferase"
                     /protein_id="BBG06550.1"
                     /transl_table=11
                     /translation="MAYPKAGSDNVPARPHFPDVELDVLDYWERHGIFHETVEARKSDE
                     EFVFYDGPPFANGLPHYGHLLAGYAKDVVPRYQTMRGRRVERRFGWTSHGLPAELDAEK
                     QLGITAKFDIERMGVARFNEVCRTTVMRYTHEWRDYVTRQARWVDFDQSVKTHDLDYME
                     SVMWAFKTVWDKGLIYQGHSVSWYCPHCETPLANAESSGRIDGSDTHREVPGTTVIVGV
                     RLDGGELLLVESDAPWALPATTAVAVHPDAEYAVVEKAGERYVVAADRLDAHAGLVGGQ
                     VRERCRGAELAGRRYQPLFDFVAPAADTHRVVAERHVDVGEGTGAVAVTPCFDERDHAV
                     ATAADIGRTYPVDSVGRYTDEVPPCAGTPVLESTGTVLGLLEAGGALLRSTPHVRSRPY
                     CWRCGTQLLQQAIPSWFVAVTRLRTRMLELNEQVNWTPEHVADGQFGKWVRGAKDWNIS
                     RNRYWGAPIPVWVSDDPAHPRVDVYGSLDEIERDFGVPGRDLHRPYIDQLTRPHPDDPT
                     GRATMRRVPEVLDCWFETGSMPFAQVHYPFENAEWFERHSPGDFVVEYYAQTRGWFYNM
                     HVMSTALFDRPAFANCTVLGVVLGHDGQAMSKARNNYLDVNDIFARDGSDAMRWFLMSS
                     PLLRARDVEVTEAGSKEALRQVLLPLWNAWHFLTLYADGDEGRVRGDAAHPLDRYLLAK
                     TRDLVDRTTRAMDDYDLSTACSGLRDHLDLLTNWYIRCSRDRFTAGDRGALDTLHTALE
                     VLCRLMAPLLPLITERVWRGLTGGRSVHLASWPTTDELPPDPELVRVMDKVREISSTAL
                     GQRKSHRLRLRLPLARLVIADRDAAALEPYTGLLRDQLNVKEIQLTTDVSAHGRMRLTP
                     NPRRCGPRLGXAVQKVLRAAAMDEWTTDADGNVVAAGIELLPDEYELRLVADGPGXAAA
                     LPGGSGLIVLDVEVTEELAAEGTARDLVRVVQQARRAAGLQVTDRIALTIDLPGATAAR
                     IRPYEALLVAETLAESLVFGPFADGGHDGLIGEGTAVRVHIATP"
     source          1..20488
                     /db_xref="taxon:1931"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp."
                     /strain="NCIMB 40513"
     misc_feature    1..20488
                     /note="SB-203208 biosynthetic gene cluster"
     subregion       1..20488
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001925"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..20488
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            3122..4720
                     /gene="sbzB"
     CDS             3122..4720
                     /NRPS_PKS="Domain: AMP-binding (9-425). E-value: 1.1e-105.
                     Score: 345.5. Matches aSDomain:
                     nrpspksdomains_sbzB_AMP-binding.1"
                     /codon_start=1
                     /gene="sbzB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     375.7; E-value: 4.9e-114)"
                     /gene_kind="biosynthetic-additional"
                     /product="AMP binding enzyme"
                     /protein_id="BBG06551.1"
                     /transl_table=11
                     /translation="MTRLEGLVSAQAARTPDADAVVFGRTRLTYRELEERSNRLAHALR
                     ADGLRPDDRVCLLVPKSPEAVVYLLGVLKAGGVCVPLDTASPAERLVSIVNRSGPCRLL
                     ADRPRTALAAELSAATAPGVVAAVCLPDGEATDGVPGCSLTAAETAAAPATAPEPVGGG
                     SDVAYVLFTSGSAGEPKGVPLTHAGIVHFVTWANEHFGLGPDDRISCHLQLHFDGSLWD
                     VYGPLTCGAELHLVPPEASLLPTTLAEFIRTSRLTQWLSVPSVLSAMARHDVMEKDDFP
                     DLRRVLWGGEVFPPPDVEYWMRRLPHVTFTGFYGTTETTIASSFHTLTDLPDQALPVGR
                     PIPGEWLEVVDDQLRPVAADEVGELVIGGAGVSPGYWRNPGRTATSFVELPPGSGRRAY
                     RTGDLGSRAADGLLRFHGRADRQVKVNGYRVELDDVMTELHALPEIAAGAVVAVPGRAG
                     GPLICAAYTLGAGVSLTTAQLKARLAGKVPAYMLPTRWLALESLPTNANGKTDLRALQR
                     LFADEETPHGGGGGA"
     aSDomain        3149..4396
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sbzB_AMP-binding.1"
                     /evalue="1.10E-105"
                     /label="sbzB_AMP-binding.1"
                     /locus_tag="sbzB"
                     /protein_end="425"
                     /protein_start="9"
                     /score="345.5"
                     /specificity="consensus: ile"
                     /tool="antismash"
                     /translation="AQAARTPDADAVVFGRTRLTYRELEERSNRLAHALRADGLRPDDR
                     VCLLVPKSPEAVVYLLGVLKAGGVCVPLDTASPAERLVSIVNRSGPCRLLADRPRTALA
                     AELSAATAPGVVAAVCLPDGEATDGVPGCSLTAAETAAAPATAPEPVGGGSDVAYVLFT
                     SGSAGEPKGVPLTHAGIVHFVTWANEHFGLGPDDRISCHLQLHFDGSLWDVYGPLTCGA
                     ELHLVPPEASLLPTTLAEFIRTSRLTQWLSVPSVLSAMARHDVMEKDDFPDLRRVLWGG
                     EVFPPPDVEYWMRRLPHVTFTGFYGTTETTIASSFHTLTDLPDQALPVGRPIPGEWLEV
                     VDDQLRPVAADEVGELVIGGAGVSPGYWRNPGRTATSFVELPPGSGRRAYRTGDLGSRA
                     ADGLLRFHGRADRQVKV"
     CDS_motif       3329..3370
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sbzB_0001"
                     /evalue="4.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="sbzB"
                     /protein_end="83"
                     /protein_start="69"
                     /score="16.8"
                     /tool="antismash"
                     /translation="LGVLKAGGVCVPLD"
     CDS_motif       3620..3679
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sbzB_0002"
                     /evalue="1.10E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="sbzB"
                     /protein_end="186"
                     /protein_start="166"
                     /score="27.2"
                     /tool="antismash"
                     /translation="AYVLFTSGSAGEPKGVPLTH"
     CDS_motif       4202..4282
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sbzB_0003"
                     /evalue="5.80E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="sbzB"
                     /protein_end="387"
                     /protein_start="360"
                     /score="37.8"
                     /tool="antismash"
                     /translation="EVGELVIGGAGVSPGYWRNPGRTATSF"
     CDS_motif       4364..4426
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sbzB_0004"
                     /evalue="2.50E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="sbzB"
                     /protein_end="435"
                     /protein_start="414"
                     /score="29.3"
                     /tool="antismash"
                     /translation="FHGRADRQVKVNGYRVELDDV"
     gene            4717..5757
                     /gene="sbzC"
     CDS             4717..5757
                     /codon_start=1
                     /gene="sbzC"
                     /product="GNAT family transferase"
                     /protein_id="BBG06552.1"
                     /transl_table=11
                     /translation="MTGFSLTGCTARDRLEIADFQDSLWRGGTAANLAYMDWKYGANPY
                     LDDRYVTLAREGRELVGMVGVFGARWEVAGERFTLPCLTDTVVAPRYQGSPLFRILTDE
                     VVARLRADGVPWLLDFGDQGAGPAMLMNGWRPVGPWGQAVLKRAKPLVADRPWHELSAV
                     RGASSGLVVRPLESVDAEAMAGLVDRLPAGTGLRPVRDAGYFRWRAANPLARYFHLVAG
                     DDPIEGYLIGHRSGVDTDDGGTPTTIVDCEATSDAVFADLVTAAVEQLPGAEVLMWVRD
                     LPAARVAALRARGAELDEPTGLFTRDMYLPNLMIRATGAEVPRALSSIHGPDMWNLSGV
                     SGRAWR"
     gene            complement(5857..6861)
                     /gene="sbzD"
     CDS             complement(5857..6861)
                     /codon_start=1
                     /gene="sbzD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 69.7; E-value:
                     4.5e-21)"
                     /gene_kind="biosynthetic-additional"
                     /product="methyltransferase"
                     /protein_id="BBG06553.1"
                     /transl_table=11
                     /translation="MTTTPHAAHVPSTDSLFSASVAVSALSAAVELGLLDELKDRGVIR
                     FDGRQEGEDRIDPAVLHGILLPLAWAGIVELDDRAARPGPGFDAAYLDRGYFYWLAGGN
                     GALTSRAPHVALERHRQGEFYRRDMRAVAVSSRMIGDVEVELRFDKILADQPPRAVCDL
                     GCGSGQRLIRMARNHPHVRGVGVDIATASVDLSVASVTEAELSDRISVHHGDVHALPRL
                     PEFAGIDVVTCVFMGHDFWPYDKCVTVLRRIREVFPDVERFLLCDVVRSEVAPGADTPI
                     FTLGFEFAHALMGVTLPTRADWMTAFAASGWECEAVQEFNRPPGGLLFELRPS"
     gene            complement(6905..7687)
                     /gene="sbzE"
     CDS             complement(6905..7687)
                     /codon_start=1
                     /gene="sbzE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 104.9; E-value:
                     7.7e-32)"
                     /gene_kind="biosynthetic-additional"
                     /product="methyltransferase"
                     /protein_id="BBG06554.1"
                     /transl_table=11
                     /translation="MGNYYYTDGFASFFDSRYTGWVHTFSPRLADHLGRQGLPERSVID
                     LCCGTGVTASVFHDAGWQVTGVDGSAAMLDIARKKLAPALDAGALHLIEADARSFRTPR
                     RAAACVSMDGALNHLESVAELTRCFTAVSEALLPGGEFVFDLYEASHFRHWNNLTVTDE
                     PDAVIVKRGVWDDGARTGMLRVSGVFGTGSSVQRVDQTLRSWEYDAAEVAGALLSAQLV
                     PAAHDFGAAYVKCDSGSCSLTSVPCRTIYRARKPLEQG"
     gene            complement(7743..8705)
                     /gene="sbzF"
     CDS             complement(7743..8705)
                     /codon_start=1
                     /gene="sbzF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083:oxidoreductase (Score: 252.1; E-value: 1.3e-76)"
                     /gene_kind="biosynthetic-additional"
                     /product="luciferase like enzyme"
                     /protein_id="BBG06555.1"
                     /transl_table=11
                     /translation="MQIHGDGVRVGVHSGQQYTTFAEALDLWQRAEELGYDWVSLFDHF
                     RPPLGGPAGPCFEGMSLLSALAARTSRIRCAVLVSAVTWRHPALAAAIAATIDHVSDGR
                     LEFGMGAAGEDLAYGQYGIPFPGAGTRLDMLDEACRVVRGLWTGGAVTFEGKHFQLRDA
                     HLEPRPRQSRLPMVIGGEGERRMLRIVAEHADIWNTLAGTPDGYRRKLTKLAEHAAVVG
                     RDPGTIRTSVTFRAILAETEQEALERKEQLLRRLGADSPVWPEYLVFGTPEQCVERLRP
                     YLDLGVRDFLLGARPPVDEQTLDLFARQVAPVLRAHPAG"
     gene            complement(8750..9007)
                     /gene="sbzG"
     CDS             complement(8750..9007)
                     /NRPS_PKS="Domain: PP-binding (9-73). E-value: 1.4e-10.
                     Score: 33.4. Matches aSDomain:
                     nrpspksdomains_sbzG_PP-binding.1"
                     /codon_start=1
                     /gene="sbzG"
                     /product="carrier protein"
                     /protein_id="BBG06556.1"
                     /transl_table=11
                     /translation="MDPLMASVAEAVRRRAQAPPPAAGLDPDAELSALGVTSLGVAGLI
                     VDLEEEFSFQFPADAVTPEVFHTLRTLTDSVRALCRHQSG"
     aSDomain        complement(8789..8980)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sbzG_PP-binding.1"
                     /evalue="1.40E-10"
                     /label="sbzG_PP-binding.1"
                     /locus_tag="sbzG"
                     /protein_end="73"
                     /protein_start="9"
                     /score="33.4"
                     /tool="antismash"
                     /translation="EAVRRRAQAPPPAAGLDPDAELSALGVTSLGVAGLIVDLEEEFSF
                     QFPADAVTPEVFHTLRTLT"
     gene            complement(9057..10061)
                     /gene="sbzH"
     CDS             complement(9057..10061)
                     /codon_start=1
                     /gene="sbzH"
                     /product="epimerase"
                     /protein_id="BBG06557.1"
                     /transl_table=11
                     /translation="MAATIRRETIGTTAGHRGQGPTAVDAYTLDTGEGLAVVVWTYGAG
                     LVEVLVPDREGRTGNVVVRLADLDAYQDRAANPYVGSTVGRYCRCVADGRFRLDGVEHR
                     LDRNDGAHHIHGGSLGFDRYVWEAEAERSDGLLSLRLRLNSPDGDQGYPGALRAEVRYQ
                     VSPEGSLAFEYRATTTASTIVGLTNHAFWNLAGGGLIDDHLLALNSSRAVVFDDQLIPV
                     AGPPADLTGSRLDHRVPAPVGDRRLDNCFLLDDPAWAAELHDPASGRTMRVVTDQPAVG
                     VYSADGFTGRRRSGLCLETGPLPDAPNRDDYPPVRLDPGETYRHRTVHHFSAR"
     gene            complement(10061..10627)
                     /gene="sbzI"
     CDS             complement(10061..10627)
                     /codon_start=1
                     /gene="sbzI"
                     /product="GNAT family transferase"
                     /protein_id="BBG06558.1"
                     /transl_table=11
                     /translation="MADTRIPAGEATAAWQWEVSRDTGEVHALLCACDAHQAAASGTSA
                     PARRLETTEHRVRSGSVHLLRHDGRPAGMFTLTWDPPFAADEGAFPPAERPLYLSRLAV
                     APEWLTGGSLVGLRCLRRAIETAAQAGGDALRSEANPDLSATRSLLDILGFVQHGPTLS
                     DGQGRRRVHLHKSLRPASPGPGGED"
     gene            complement(10630..12024)
                     /gene="sbzJ"
     CDS             complement(10630..12024)
                     /codon_start=1
                     /gene="sbzJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 348; E-value:
                     1.1e-105)"
                     /gene_kind="biosynthetic-additional"
                     /product="aldehyde dehydrogenase"
                     /protein_id="BBG06559.1"
                     /transl_table=11
                     /translation="MPQERQKRSARMEDTQVAVLTDPRTGRERRRIALAGEPEVTAAVA
                     EARGAGSAWAALTPRLRARCLLRFADLIEERSAQYVVAERSGTGKPAAEAAGEVESCAD
                     LLRFYAGALRAGTAPAAGRLLPGRESWVRWEPLGVVAAIVPWNYPLMMAAWRIGPALAA
                     GNTVVLKPALTTPDTALLLARDAAETLGPGVLVTVPGDRDTGRLLVESAVDAVAFTGSE
                     AAGRDIVGRAGLRRLSLELGGNCPAVVLPDAPPDTYEALVRAATYNAGQSCASPSRVIT
                     LRENYQQAVEGLAKAMHARRAGVDFGPLNNADQAARYDRIVARSGAGIEHVAPLAPPPG
                     EEGGHWRPGRILADLPADDPAVCEEVFAPVLTVQAADDPAEALALANGMPQALAASVWG
                     SRTDAVLELAGELNAGEVWVNCHLEQTAELPHGGRGTSGHGTDMSVLALTEYQRPKTVT
                     VRLGGS"
     gene            complement(12039..12320)
                     /gene="sbzK"
     CDS             complement(12039..12320)
                     /NRPS_PKS="Domain: PP-binding (8-76). E-value: 1.2e-10.
                     Score: 33.6. Matches aSDomain:
                     nrpspksdomains_sbzK_PP-binding.1"
                     /codon_start=1
                     /gene="sbzK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147:putative acyl carrier protein (Score: 55.8;
                     E-value: 5.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /product="carrier protein"
                     /protein_id="BBG06560.1"
                     /transl_table=11
                     /translation="MNDPSGMTDRVARLLGDVLHIDPPAPGIDLIGTGLLDSIGFMHLF
                     VALEREFGIGVATGDLSPDRFRTVESIAAFVAAKQGGEQGPVVPAAAP"
     aSDomain        complement(12093..12296)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sbzK_PP-binding.1"
                     /evalue="1.20E-10"
                     /label="sbzK_PP-binding.1"
                     /locus_tag="sbzK"
                     /protein_end="76"
                     /protein_start="8"
                     /score="33.6"
                     /tool="antismash"
                     /translation="DRVARLLGDVLHIDPPAPGIDLIGTGLLDSIGFMHLFVALEREFG
                     IGVATGDLSPDRFRTVESIAAFV"
     gene            complement(12317..13996)
                     /gene="sbzL"
     CDS             complement(12317..13996)
                     /NRPS_PKS="Domain: AMP-binding (35-438). E-value: 8.4e-78.
                     Score: 253.5. Matches aSDomain:
                     nrpspksdomains_sbzL_AMP-binding.1"
                     /codon_start=1
                     /gene="sbzL"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 298;
                     E-value: 1.7e-90)"
                     /gene_kind="biosynthetic-additional"
                     /product="AMP binding enzyme"
                     /protein_id="BBG06561.1"
                     /transl_table=11
                     /translation="MVSSSPTDAERAHTYRGIPFEDRLTPHPTVVSWLVHHARTRGGAP
                     FLTTVSGDGEPSTLTYGELDVLSRRVARWLRAELDIAPGRTVALAPANDPVSVVALLGV
                     LRAGCALLLLGPQDPADRRRQQAEAARAQVVLRSPAVPAEALPEAVVIPDPGTLADPAG
                     PDADPVLDPAQDALFFATSGSTAAAKLVAQSHYNAAVNAEALGRHHGLRPGDRLLGCLP
                     VHHVNGLHFTVLGVLAAGAHVLLADGFAPLRYPRLLQRFRPRIASVVPSVLEALLETWR
                     QPELPADFGYFVSAAAPLTVRTARAVRDRFGARVLQGYGLTETVNFSTTLPADLSEDAY
                     RRLMLDTDIPSIGTALYGNEVAVLTPEGTRATPGQVGEICVRGHNVMSRYEANPHATAE
                     AFAGGWFHTQDLGLEVTDPDCDGPFIVITGRRKNIAKVGGETVSLDEMDRVLRAHPQVR
                     DAACAALPHRFLGEEIVAAVVPASGAQGPPDVRPALAAAFRPGVLPRRVELLDAIPRTR
                     TGKVLRRELANRLAGTDTADGVHGPRTPATPDSPRPNSGSTR"
     aSDomain        complement(12683..13891)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sbzL_AMP-binding.1"
                     /evalue="8.40E-78"
                     /label="sbzL_AMP-binding.1"
                     /locus_tag="sbzL"
                     /protein_end="438"
                     /protein_start="35"
                     /score="253.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="HHARTRGGAPFLTTVSGDGEPSTLTYGELDVLSRRVARWLRAELD
                     IAPGRTVALAPANDPVSVVALLGVLRAGCALLLLGPQDPADRRRQQAEAARAQVVLRSP
                     AVPAEALPEAVVIPDPGTLADPAGPDADPVLDPAQDALFFATSGSTAAAKLVAQSHYNA
                     AVNAEALGRHHGLRPGDRLLGCLPVHHVNGLHFTVLGVLAAGAHVLLADGFAPLRYPRL
                     LQRFRPRIASVVPSVLEALLETWRQPELPADFGYFVSAAAPLTVRTARAVRDRFGARVL
                     QGYGLTETVNFSTTLPADLSEDAYRRLMLDTDIPSIGTALYGNEVAVLTPEGTRATPGQ
                     VGEICVRGHNVMSRYEANPHATAEAFAGGWFHTQDLGLEVTDPDCDGPFIVITGRRKNI
                     AKVG"
     CDS_motif       complement(12794..12880)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sbzL_0003"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="sbzL"
                     /protein_end="401"
                     /protein_start="372"
                     /score="19.8"
                     /tool="antismash"
                     /translation="PGQVGEICVRGHNVMSRYEANPHATAEAF"
     CDS_motif       complement(13265..13297)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sbzL_0002"
                     /evalue="3.30E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="sbzL"
                     /protein_end="244"
                     /protein_start="233"
                     /score="2.1"
                     /tool="antismash"
                     /translation="LGVLAAGAHVL"
     CDS_motif       complement(13655..13693)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_sbzL_0001"
                     /evalue="1.60E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="sbzL"
                     /protein_end="114"
                     /protein_start="101"
                     /score="6.0"
                     /tool="antismash"
                     /translation="LGVLRAGCALLLL"
     gene            complement(14000..14686)
                     /gene="sbzM"
     CDS             complement(14000..14686)
                     /codon_start=1
                     /gene="sbzM"
                     /product="cupin dioxygenase"
                     /protein_id="BBG06562.1"
                     /transl_table=11
                     /translation="MSTQQVIAMLTEELHDLDPAERQAKTVELLAVFGRAKAEALQPEE
                     RPEAPDTKPGPLLICDWAADLGLDGTTQQLGIEVAPGPTKVTKTADATGHSLASSGHVG
                     ADILHVPAGSGFAPHTHPGDHLLFVLAGTGTIAVAGEIVRTRPGQVYMVQGDITHAVGA
                     VTDHMILSVGAPHRRLDSPDRQELTAYAALLGELGEITCRLCDISAAGGEELAAKGCTH
                     SPHRFG"
     gene            complement(14704..15861)
                     /gene="sbzN"
     CDS             complement(14704..15861)
                     /codon_start=1
                     /gene="sbzN"
                     /product="isomerase"
                     /protein_id="BBG06563.1"
                     /transl_table=11
                     /translation="MSDGNGPAAGSQAPPPLDPQVMLRQVAALAEDLREQTGPFDEQVR
                     SRLSARWAAVDSVTIVGDGDSYHAACAVQMAFASLAGVDCRPVNALRFVDYDLPFADCR
                     PSRTELTLAVSASGRTPLVVRSAERAREAGATAVAVTATSGSALAGASDGALLVTLPRT
                     ERSPGVRSYQASLLGLLLIAIRLGEARERLTRQEADALRGELTALAGPVEATAEAARER
                     CREPAERIAGAPVLTVVGSGPSYGTALFGAAKVIETSGVFATGQDLEEWCHVERFARPA
                     DMPMVVVAAPGRSYRHAVEVAAKAAALGRRVIAVAPEDDTGLARHSWAALPVTGRVREE
                     FSPLLYHVFAAPLSCYLAQHLGRAPFLADRRPDPAPTPRHDGETP"
     gene            complement(15858..16664)
                     /gene="sbzO"
     CDS             complement(15858..16664)
                     /codon_start=1
                     /gene="sbzO"
                     /product="BtpA like enzyme"
                     /protein_id="BBG06564.1"
                     /transl_table=11
                     /translation="MDGWTAPGGHKLVLGMVHLSPLPGTPFHEDGSFDRVRDTAVRSAR
                     ALYEGGADGCLIQTVDRVYRVDDVSDPARTVAMGLIVRAVAEATDERFHIGVQLMRNAL
                     TPSLAVAKVAGGSYIRAGALVGQTLTPHGMVRPDPMEVMAYRRRIGATDVRIVAEIDSM
                     HFRWFGGEKSTAEVARAARAVGADAVSLCHPDEDTALEMIAAVRKAVPDLPVILAGHTR
                     HDNAARLLAAADGAFVGTCLERDGWGGEIDRDRVAAYVDIVRRLER"
     gene            complement(16668..18239)
                     /gene="sbzP"
     CDS             complement(16668..18239)
                     /NRPS_PKS="Domain: Aminotran_1_2 (137-361). E-value:
                     8.9e-20. Score: 62.9. Matches aSDomain:
                     nrpspksdomains_sbzP_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="sbzP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 111.4; E-value:
                     8.3e-34)"
                     /gene_kind="biosynthetic-additional"
                     /product="PLP binding enzyme"
                     /protein_id="BBG06565.1"
                     /transl_table=11
                     /translation="MKLFESLPSPRPRYTPQDARETAARAPQPGGVRDVFTPGIDERVL
                     EVYARARDPHDPLELRDLWLGRVEHELGAHALRPELAEGWRASRPRRTVGAEEVLSSRA
                     TVRFVKELFNSFFRDDLYGELRDNARYILSSGSIDEEKWGLPQSLKECIRYALDRDWYG
                     YSDSRGRVPAREAIAAYENARITGARYGAANVAITMGGTFAISTLADFVLHDGPRSSSP
                     ALCAIPNYPPLVESVARRHEVQLVPLASEGGQTSVDPVIAALTPDTPLVMLQTVGNPTG
                     AAVTESELARLIRAASPSTIIVLDECHEWLGTYEERSPERAAPNVVRVSSLSKSWSAPG
                     LKAGWFLADPAFIDEYYEYASSSFGGPPSFFYTVIEVLARLERWLITGVEVPGPAEAKE
                     FEASYSMDLAQLRNAYRGYRTERLRRAEDLTVLRDAATVRLAETSGLVLPPRFSINTAV
                     EFPGWDDSYRCFRDILRETGVSVFPGILTFCLSGGVVRVTTARSWDELAPAIDRLRSHA
                     GRTTGS"
     aSDomain        complement(17157..17828)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_sbzP_Aminotran_1_2.1"
                     /evalue="8.90E-20"
                     /label="sbzP_Aminotran_1_2.1"
                     /locus_tag="sbzP"
                     /protein_end="361"
                     /protein_start="137"
                     /score="62.9"
                     /tool="antismash"
                     /translation="IDEEKWGLPQSLKECIRYALDRDWYGYSDSRGRVPAREAIAAYEN
                     ARITGARYGAANVAITMGGTFAISTLADFVLHDGPRSSSPALCAIPNYPPLVESVARRH
                     EVQLVPLASEGGQTSVDPVIAALTPDTPLVMLQTVGNPTGAAVTESELARLIRAASPST
                     IIVLDECHEWLGTYEERSPERAAPNVVRVSSLSKSWSAPGLKAGWFLADPAFIDEYYEY
                     AS"
     gene            complement(18324..19238)
                     /gene="sbzQ"
     CDS             complement(18324..19238)
                     /codon_start=1
                     /gene="sbzQ"
                     /product="alpha-ketoglutarate-dependent dioxygenase"
                     /protein_id="BBG06566.1"
                     /transl_table=11
                     /translation="MEQRSPTSPTRPAAPREPGGGVTHGTFLTAADDPHVPLRERTLGN
                     GTPLRDLAPRPGPATGPHDALHAEVSDQLWRRGLAAVQLDEPLPNDRFTALGAFLGTAM
                     PERDPAVRPYVEDEVILNLRSEHRRTDDVSLQPFAGNYLSLHTESSGGPVERQPRYIVL
                     MCVAPGDASQGARTVLVPMRDVARRVAPRTTDVLSRTRYRHHPGVPTIARKAGDRWVFS
                     FRDFLTDELHWTREGPEGDAVAVNDALRDLLAAMYAPGHARAVHWRRGLLVVIDNTYFF
                     HGRTAGSAAPEARLRHLKRLRIV"
     gene            complement(19259..20488)
                     /gene="sbzR"
     CDS             complement(19259..20488)
                     /codon_start=1
                     /gene="sbzR"
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 205.4; E-value: 1.6e-62)"
                     /gene_kind="transport"
                     /product="MFS family transporter"
                     /protein_id="BBG06567.1"
                     /transl_table=11
                     /translation="MLNRILPASGPGRVLAVATLFITLGQGAFMTCSALYFTTVVGISV
                     TQLGLGLTLAGAVGLFAGVPLGHLADRRGPRGTAALLTAANGVAAAGYLVVGSFVQFTV
                     SACLFVMLERGSRAALQAAVAGTLDGGDLVETRAYLRAVTNAGVAVGAGLAGIALQVNT
                     PAAFRTVLVLDALFFLVAAGVLTRLPRVAPKPASDEDAGRPRLAVLRDRPFALVTALTA
                     VLSLHAVLLEIVVPLWIATHTAAPRWLVTVLFLLNTVSVVAFQVRIAKRVTQVPLAVRA
                     VLRAGIVLCVACALFAASATDSVAAAVTFLVLAGAVHVYGEMVLSAGAWVIGFDLAPAD
                     MQGQYQGFFFTGYATAAMIAPSFLTLTVVQGGAVGWLLLGGLFILASLAMKPAVGWAER
                     TRSVRPAHCG"
ORIGIN
        1 atggcatatc cgaaagccgg gtccgacaac gtacccgcga gaccacactt tccggacgtc
       61 gaactcgatg tgctggatta ctgggaacgc cacggcatct tccacgagac ggtggaggcg
      121 cggaaatccg acgaagaatt cgtgttctac gacggaccgc cgttcgccaa cggcctgccg
      181 cactacggac atctgctggc cgggtatgcc aaggacgtgg tgccgcggta ccagaccatg
      241 cggggacgca gggtcgagcg acgcttcggc tggacctcac acgggctgcc cgccgaactc
      301 gatgccgaga agcaactcgg tatcaccgcg aagttcgata tcgagcgcat gggcgtcgcc
      361 cgattcaacg aggtctgccg caccacggtg atgcgctaca cccatgagtg gcgcgactat
      421 gtcacccgcc aggcccgctg ggtcgacttc gaccagtccg tcaagaccca tgacctcgac
      481 tacatggaga gcgtcatgtg ggcgttcaag accgtgtggg acaaggggct catctaccaa
      541 ggacattcgg tctcctggta ctgcccgcac tgtgagacgc cgctcgccaa cgcggagagc
      601 agcggccgta tcgacggcag tgacacccat cgcgaggtgc cgggtaccac cgtgatcgtg
      661 ggcgtgcggc tggacggcgg cgagctgctg ctggtggagt ccgacgcgcc ctgggcgctg
      721 cccgccacca cggcggtggc cgtgcatccc gacgccgaat acgccgtggt cgaaaaggcg
      781 ggggagcgct acgtggtggc ggctgaccgg ctcgacgccc acgccggcct ggtgggcggg
      841 caggtgcggg aacggtgccg cggcgccgag ctggcgggac gccggtacca gccgctgttc
      901 gacttcgtcg ctcccgcggc ggacacgcac cgcgtggtgg cggaacggca tgtggacgtc
      961 ggcgagggca ccggtgccgt cgccgtgacc ccgtgcttcg atgagcgcga ccatgccgtt
     1021 gcgacggccg cggacatcgg ccggacctac ccggtcgact ccgtcggcag gtacaccgac
     1081 gaggtgccgc cgtgcgccgg aacgccggta ctggagtcca ccgggaccgt gctcgggctg
     1141 ctggaggccg gcggtgcgct gctgcgcagc accccgcacg tccgctcccg gccgtactgc
     1201 tggcgctgtg gcacacagct gctgcaacag gccatcccct cctggttcgt ggccgtgacg
     1261 cggctgcgca cccggatgct ggagctcaac gagcaggtca actggacgcc ggaacacgtg
     1321 gcggacggcc agttcggcaa gtgggtgcgc ggcgccaagg actggaacat ctcccgcaac
     1381 cgctactggg gcgcccccat cccggtgtgg gtatcggacg atcccgcaca cccccgggtc
     1441 gacgtgtacg gctcgctgga cgagatcgag cgtgacttcg gggtccccgg ccgcgacctg
     1501 caccgtccgt acatcgacca gctcacccgc ccccacccgg acgaccccac gggccgggcg
     1561 acgatgcggc gggtgcccga ggtactggac tgctggttcg agaccggctc catgccgttc
     1621 gcgcaggtgc actacccctt cgagaacgcc gagtggttcg agcggcactc gccgggcgac
     1681 ttcgtggtcg agtactacgc ccagacccgc ggctggttct acaacatgca cgtcatgtcc
     1741 acggcgctgt tcgaccggcc ggccttcgcc aactgcaccg tcctcggcgt ggtgctcggc
     1801 cacgacggac aggcgatgtc caaggcccgc aacaactacc tcgacgtgaa cgacatcttc
     1861 gcccgtgacg gctccgacgc catgcgctgg ttcctcatga gctcgccgct gctgcgcgcc
     1921 cgcgacgtgg aggtcaccga ggccggcagc aaggaggccc tgcgccaggt gctgctgccg
     1981 ctgtggaacg cctggcactt cctgacgctg tacgcggacg gcgacgaggg ccgtgtccgc
     2041 ggcgacgcgg cacatccgct ggaccgctac ctcctggcca agacccggga tctggtcgac
     2101 cggacgaccc gcgcgatgga cgactacgac ctctccaccg cgtgctccgg gctgcgggac
     2161 cacctggacc tgctgaccaa ctggtacatc cgctgctccc gcgaccggtt cacggccggc
     2221 gaccgcgggg ccctggacac cttgcacacc gcgctcgaag tgctgtgccg gctgatggcg
     2281 cccctgctgc cgctgatcac cgagcgggtg tggcgagggc tgaccggggg ccggtcggtg
     2341 cacctggcct cgtggcccac gacggacgag ctgccgccgg atccggaact ggtgcgcgtg
     2401 atggacaagg tgcgggagat ctcctcgacc gcgctcggtc agcgcaagag ccaccggctg
     2461 cggctgcgcc tgcccttggc acgactggtg atcgccgacc gcgacgccgc cgcgctggag
     2521 ccctacaccg gactgctgcg cgaccagctc aacgtcaagg agatccagct caccaccgat
     2581 gtctccgcac acggcaggat gcggctgacc cccaaccccc gccggtgcgg accccgcctc
     2641 ggcngcgcgg tgcaaaaggt gctccgcgcc gccgccatgg acgagtggac cacggacgcc
     2701 gacgggaacg tcgtggcggc aggcatcgaa ctgctccccg acgagtacga gttgcggctg
     2761 gtcgccgacg gcccgggcgn cgccgcggca cttcccggcg gatccggact gatcgtgctc
     2821 gacgtcgagg tgaccgagga gctggcggcc gagggcacgg cccgcgatct ggtgcgggtg
     2881 gtgcagcagg cacgccgcgc ggccggcctc caggtcaccg accgcatcgc gctgaccatc
     2941 gacctgccag gggcgacggc ggcacgcatc cggccgtacg aggcgcttct cgtggcggag
     3001 accctcgccg agtcactggt gttcggtccg ttcgcggacg gcggtcacga cggcctcatc
     3061 ggcgagggca ccgcggttcg ggtgcacatc gccacgccct gaccaaggaa ggaagcagcg
     3121 catgacgcgc ctcgaagggc ttgtgagcgc acaagccgcc cgaacgccgg acgcggacgc
     3181 ggtcgtcttc ggccggaccc ggctcaccta ccgcgagctg gaggagcggt ccaaccggct
     3241 ggcccacgca ctgcgcgccg acggactgcg cccggacgac cgggtgtgcc tgctggtgcc
     3301 gaagagcccg gaagcggtgg tgtacctgct cggcgtgctc aaggccggcg gcgtgtgcgt
     3361 gccgctggac accgcgtcgc cggcggagcg gctggtgtcc atcgtgaacc ggagcgggcc
     3421 gtgccggctc ctcgccgacc gcccgcgcac cgccctggcc gccgagctgt cggccgccac
     3481 cgcgcccggc gtggtggcgg ccgtatgcct gcccgacggc gaggccacgg acggtgttcc
     3541 cggatgctcg ctcaccgccg ccgagaccgc cgccgcgccg gcgaccgcgc ccgagccggt
     3601 gggcggcggc tccgacgtcg cctacgtcct gttcacctcg ggctcggcgg gcgaacccaa
     3661 gggcgtgccg ctcacccacg ccggcatcgt ccacttcgtg acctgggcca acgagcactt
     3721 cgggctcggg ccggacgacc ggatctcctg ccacctccaa ctgcacttcg acggctcgct
     3781 gtgggatgtg tacgggccgc tgacctgcgg cgccgaactg cacctggtcc ctccggaggc
     3841 cagcctgctg ccgaccaccc tggccgagtt catccgcacc tcacggctga cccagtggct
     3901 ctcggtcccg tcggtactca gtgcgatggc gcggcacgac gtgatggaga aggacgactt
     3961 cccggacctg cggcgggtgc tgtggggcgg cgaagtcttc ccgcccccgg acgtcgagta
     4021 ctggatgcgc cgcctgcccc acgtgacgtt caccgggttc tacggcacca ccgagaccac
     4081 catcgccagt tccttccaca cgctgaccga cctgccggat caggcgctgc ccgtcggccg
     4141 gcccatcccc ggggagtggc tggaggtcgt cgacgaccag ctgcgcccgg tcgccgccga
     4201 tgaggtgggc gagctggtga tcggcggcgc cggggtcagc cccggctact ggcgcaatcc
     4261 cggacggacc gcgacctcgt tcgtcgagct gccccccggc agcggacggc gcgcgtaccg
     4321 caccggcgat ctgggcagcc gggccgcgga cggactgctg cgcttccacg gccgtgccga
     4381 ccgccaggtc aaggtcaacg gctaccgggt ggaactcgac gacgtgatga ccgaactgca
     4441 cgcactgccc gagatcgccg caggggcggt cgtggccgtg ccgggccgtg ccggcggtcc
     4501 gctgatctgc gcggcctaca ccctcggcgc cggggtctcg ctgaccaccg cgcagctgaa
     4561 ggccaggctc gccgggaagg tgcccgccta catgctgccg acgcgctggc tggcactgga
     4621 gtcgctgccc accaacgcca acggcaagac cgacctgcgg gcactccagc ggctcttcgc
     4681 cgacgaggag acaccgcacg gcggaggtgg cggcgcgtga ccgggttctc cctcaccgga
     4741 tgcacggccc gcgaccgcct ggagatcgcg gacttccagg actcgctgtg gcgcggcgga
     4801 acggcggcca atctggcgta catggactgg aagtacggcg ccaaccccta cctcgacgac
     4861 cggtacgtca ccctcgcccg agagggacgg gaactggtcg gcatggtggg cgtcttcggg
     4921 gcgcgctggg aggtggcggg ggagcggttc accctgccct gcctcaccga caccgtggtc
     4981 gccccccgct accagggcag ccccctgttc cggatcctga ccgacgaggt ggtggcccgg
     5041 ctgcgcgccg acggtgtgcc gtggctgctg gacttcggcg accagggggc cggccccgcc
     5101 atgctgatga acggctggcg cccggtcggg ccatgggggc aggccgtgct gaagcgggcg
     5161 aagccgctgg tggcggaccg gccgtggcac gagctgtccg ctgtgcgggg ggcgagttcc
     5221 ggcctggtcg tacgtccgct ggagtccgtg gacgcggagg ccatggccgg tctggtggac
     5281 cgtctgccgg ccggcaccgg cctgcgcccg gtgcgggacg ccggctactt ccgctggcgc
     5341 gcggcgaacc cactggcccg gtacttccat ctggtggcgg gggacgaccc catcgagggc
     5401 tacctcatcg gacaccgctc cggcgtcgac accgacgacg gcgggacccc caccacgatc
     5461 gtggactgcg aggcgacctc cgacgcggtg ttcgcggact tggtgacggc cgcggtcgag
     5521 cagctgccgg gcgccgaggt cctgatgtgg gtacgcgatc tgccggcggc acgggtcgcg
     5581 gcgctgcgcg cacggggtgc cgaactcgac gaacccaccg ggctgttcac ccgcgacatg
     5641 tacctcccca acctgatgat ccgggcgacc ggcgccgagg tgccgagggc gctcagcagc
     5701 atccacgggc cggacatgtg gaacctcagc ggtgtgtccg gccgcgcgtg gcgatgaccc
     5761 gtacgaccgc cggctgacgc ctccgccgcc gtggaccgac agcgcactgc tcgccttcca
     5821 gaagtccggt acctctggaa ggcgagcagt gttgcgtcag ctggggcgca gctcgaagag
     5881 cagaccgccg ggcggccggt tgaactcctg gaccgcctcg cactcccaac cggaagcggc
     5941 gaacgccgtc atccagtccg cgcgcgtcgg cagcgtgacg cccatgagcg cgtgcgcgaa
     6001 ctcaaagccc aacgtgaaga tcggggtgtc cgctccgggc gccacctcgc tgcgcaccac
     6061 atcgcacagc aggaaccgtt cgacgtcggg aaacacctcg cggatccggc gcagcacggt
     6121 cacacacttg tcgtacggcc agaagtcgtg ccccatgaac acacaggtga ctacgtcgat
     6181 accggcgaat tcgggcagtc ggggcagggc gtgcacatcg ccgtggtgca cggagatccg
     6241 gtccgacagc tcggcctcgg tgaccgaggc caccgacaga tccacggagg cggtggcgat
     6301 gtccaccccg acgccccgga catggggatg gttgcgcgcc atacggatga gccgttggcc
     6361 cgatccgcac ccgaggtcgc acaccgctcg gggtggctgg tcggcgagta tcttgtcgaa
     6421 gcgcaactcg acctcgacat cgccgatcat ccgggagctc accgccacgg cccgcatgtc
     6481 cctgcggtag aactcgccct gccggtggcg ctccagcgcg acgtgcggcg cccggctcgt
     6541 cagcgcgccg ttgccgccgg ccagccagta gaagtagccg cggtccaggt aggccgcgtc
     6601 gaagcccggc cccggccggg ccgcccggtc gtcgagttcg acgatcccgg cccacgccag
     6661 ggggaggagg atgccgtgga gcacggcggg gtcgatgcgg tcctcgccct cctggcggcc
     6721 gtcgaaccgg atgacgcccc ggtccttgag ttcgtcgagc agcccgagtt cgacggccgc
     6781 cgacagtgcg gaaaccgcca cggacgcact gaacagggaa tcggtgctcg ggacatgggc
     6841 agcgtgcgga gtagtggtca tcgctgatcc tttgtgagtg gtggggtggt cgcggcggtg
     6901 ctggtcaccc ctgttccagg ggcttgcggg cgcggtagat cgtgcggcag ggcacgctgg
     6961 tcagggagca ggagcccgaa tcgcatttga cgtacgccgc cccgaagtcg tgtgcggccg
     7021 ggacgagttg ggccgacagc agcgcacccg ccacctcggc ggcgtcgtac tcccagctgc
     7081 gcagtgtctg gtccacccgc tggacggagc tgcccgtgcc gaacaccccg gacacccgca
     7141 gcatcccggt ccgtgcgccg tcgtcccaga caccgcgttt gacgatgacc gcgtccggct
     7201 cgtccgtcac ggtgaggttg ttccagtggc ggaagtgcga cgcctcgtag aggtcgaaga
     7261 cgaactcccc gccgggcagc agcgcctcgc tcaccgcggt gaaacaccgc gtcagctccg
     7321 ctaccgactc caggtggttg agcgcaccgt ccatgctcac gcaggccgcg gcccgccgtg
     7381 gcgtacggaa ggaccgggca tcggcttcga tgaggtggag cgccccggca tcaagggcgg
     7441 gggccagctt cttgcgcgcg atgtccagca tggcggccga tccgtccacg ccggtgacct
     7501 gccagccggc gtcgtggaag acggacgccg tgacgcccgt gccgcagcac aggtcgatca
     7561 ccgaacgctc cgggagcccc tgccgtccca gatggtcggc gagccggggc gagaaggtgt
     7621 gcacccaccc cgtgtaccgg ctgtcgaaga aggacgcgaa accgtccgtg tagtaatagt
     7681 tccccatggt gagcctccgt gggccgtggt gtggatgaac cggcgaccgg gccggcgcct
     7741 ggtcagccgg ccgggtgggc gcgcagcacc ggcgcgacct gccgggcgaa gagatcgagg
     7801 gtctgctcgt ctacgggagg gcgggcgccg agcaggaaat cgcggacacc caggtcgaga
     7861 tagggacgca gccgctcgac gcactgctcg ggggtgccga acaccaggta ctccggccac
     7921 accggcgaat cggcgcccag tctccgcagc agctgctcct tgcgctccag ggcctcctgc
     7981 tcggtctcgg cgagtatcgc ccggaacgtc accgatgtgc ggatggtccc gggatcgcgg
     8041 ccgacgacgg cggcatgttc ggccagcttc gtgagcttgc gccggtagcc gtccggagtt
     8101 ccggccaggg tgttccagat atcggcgtgc tcggcgacga tccgcagcat ccgccgctcg
     8161 ccctcgccac cgatcaccat cggcagccgt gactgacggg ggcgcggctc cagatgggcg
     8221 tcccggagct gaaagtgctt cccttcgaag gtcaccgccc cgccggtcca cagtccccgt
     8281 acgacccggc aggcctcgtc cagcatgtcc agccgcgtcc cggcgcccgg gaaggggatg
     8341 ccgtactgcc cgtaggcgag gtcctcgccg gccgcgccca tcccgaactc caggcggccg
     8401 tccgagacgt ggtcgatggt cgccgcgatg gccgcggcca gtgccggatg ccgccaggtc
     8461 accgccgaga cgagcacggc gcagcggatc cggctggtgc gtgccgccag cgccgagagc
     8521 agcgacatgc cctcgaagca cgggccggcc gggccgccga gcggcggacg gaagtggtcg
     8581 aagagggaga cccagtcgta cccgagttcc tccgcccgct gccacaggtc gagcgcctcg
     8641 gcgaaggtcg tgtactgctg gcccgagtgg acgccgactc ggacgccgtc tccatggatc
     8701 tgcatgatgt ccgctccgtg aaaggactgc ccgggaaccg ggccggggtt cagcccgact
     8761 ggtggcggca cagtgcgcgg accgagtcgg tgagggtgcg aagggtgtgg aacacctcgg
     8821 gggtgaccgc atcggccggg aactggaagg agaactcctc ctccagatcc acgatcagac
     8881 cggccacacc cagcgaggtc acgccgaggg cggacagctc cgcgtccggg tccagcccgg
     8941 cggccggtgg cggcgcctgc gcgcgacgcc gtacggcctc cgccacggaa gccatgaggg
     9001 ggtccattta ggggttacct cctgttgagg gtcatggccc ggccggtggg ggcgggtcag
     9061 cgggccgaga agtggtggac ggtgcggtgg cggtaggtct caccggggtc gaggcggacc
     9121 gggggatagt cgtcgcggtt cggcgcgtcc ggcagcgggc ccgtctccag acacaggccg
     9181 gaccgccgcc gcccggtgaa tccgtcggcg gagtacaccc ccaccgcggg ctggtcggtg
     9241 acgacgcgca tggtgcgccc cgaggcgggg tcgtgcagct ccgccgccca ggccgggtcg
     9301 tccaggagga agcagttgtc cagccgacgg tcgccgacgg gcgccggcac gcggtggtcc
     9361 agccggctgc cggtgaggtc agcgggcggc ccggcgaccg ggatgagctg gtcgtcgaag
     9421 accaccgccc gggaggagtt gagcgccagc aggtggtcgt cgatcaggcc gccgccggcc
     9481 aggttccaga acgcgtgatt ggtcagcccc acgatggtgc tcgcggtggt cgtggcccgg
     9541 tactcgaagg ccagactccc ctcgggggac acctggtagc ggacctcggc gcgcagcgca
     9601 ccggggtagc cctggtcgcc gtccgggctg ttgaggcgca gtcgcagcga cagcagaccg
     9661 tccgagcgtt ccgcctccgc ctcccacacg taccggtcga agccgaggga cccgccgtgg
     9721 atgtggtggg cgccgtcgtt gcggtcgagc cggtgctcca caccgtcgag ccggaaccgg
     9781 ccgtccgcca cgcaccggca gtaacggccc acggtcgagc cgacatacgg gttggccgcc
     9841 cggtcctggt aggcgtcgag gtccgcgagc cgcaccacca cattgccggt acggccctcg
     9901 cggtcgggga ccaggacctc cacgagcccg gccccgtacg tccacaccac gacggccagg
     9961 ccctcgccgg tgtcgagggt gtaggcgtcc acggcggtcg gcccctggcc gcggtgtccg
    10021 gcggtggtgc cgatcgtctc gcgccggatc gtcgctgcca tcagtcctcc ccgcccgggc
    10081 ccggggacgc agggcggagg gacttgtgga gatggacgcg gcgcctgccc tgcccgtcgc
    10141 tcagcgtggg cccgtgctga acgaacccca ggatgtcgag cagggaccgg gtggccgaca
    10201 ggtccgggtt ggcctccgag cgcagtgcgt caccgccggc ctgtgccgcg gtctcgatgg
    10261 cccggcgcag gcagcgcagc ccgaccaggg acccacccgt cagccactcg ggcgcgacgg
    10321 ccagccgcga cagatacagg ggccgttcgg caggagggaa ggcgccctcg tccgcggcga
    10381 acggcgggtc ccaggtcagg gtgaacatgc cggcgggccg gccgtcgtgg cgcagcaggt
    10441 gcacggagcc ggagcgcacc cggtgctcgg tggtctccag gcgccgcgcc ggcgccgacg
    10501 tgccggaggc cgcagcctgg tgggcgtcgc acgcgcacag cagcgcgtgc acctccccgg
    10561 tgtcgcggct cacctcccac tgccacgcgg ccgtcgcttc cccggccgga atgcgggtgt
    10621 ccgccatgct cagctcccgc ccagacgtac ggtgacggtc ttgggccgct ggtactcggt
    10681 gagcgccagc acgctcatgt ccgtaccgtg cccggacgtg ccgcgcccgc cgtggggcag
    10741 ttccgcggtc tgctccagat ggcagttgac ccacacctcg ccggcgttca gctcgccggc
    10801 cagttccaga accgcgtccg tgcgcgagcc ccagacgctc gcggcgaggg cctgcggcat
    10861 cccgttggcc agcgccaggg cctcggcggg atcgtccgcc gcctgcaccg tgagcaccgg
    10921 cgcgaacacc tcctcgcaca ccgcgggatc gtccgccggc aggtcggcga ggatgcggcc
    10981 gggccgccag tggccgccct cctcgcccgg gggcggcgcg agcggggcga catgctcgat
    11041 gcccgccccg ctccgcgcga cgatccggtc gtaacgggcc gcctggtccg cgttgttgag
    11101 tggcccgaag tcgacgcccg cgcgccgggc gtgcatggcc ttggccagcc cctccacggc
    11161 ctgctggtag ttctcccgca gggtgatgac ccgggagggg gaggcacagc tctgcccggc
    11221 gttgtaggtg gccgcgcgca ccagcgcctc ataggtgtcc ggtggcgcgt ccggcagtac
    11281 caccgcgggg cagttgccgc cgagctccag gctgagccgg cgcaggcccg cgcggccgac
    11341 gatgtcgcgc ccggccgcct cgctgccggt gaacgccacc gcgtcgacag cgctctccac
    11401 cagcaggcgg ccggtgtcgc ggtcacccgg cacggtcacc aggacaccgg gccccagcgt
    11461 ctcggccgcg tcccgggcca gcagcagcgc ggtgtccggg gtcgtcaggg cgggcttgag
    11521 gaccacggtg ttgcccgcgg cgagcgcggg gccgatccgc cacgcggcca tcatcaacgg
    11581 gtagttccag ggcacgatcg ccgcgacgac gcccagcggc tcccaccgca cccagctctc
    11641 ccgtccgggc agcaggcggc cggcggccgg ggccgtgccg gcgcgcagcg cgcccgcgta
    11701 gaagcgcagc agatcggcgc acgactcgac ctcaccggcc gcttcggcag cgggtttgcc
    11761 ggtacctgac cgctcggcca ccacgtattg cgccgaccgt tcctcgatca ggtcggcgaa
    11821 gcgcagcagg caccgtgccc ttagccgtgg ggtgagggcg gcccacgcgg acccggcgcc
    11881 gcgggcttcg gccacggcgg ccgtcacctc cggctcgccg gcgagagcga tccgccgtcg
    11941 ctcgcgtccc gtgcgggggt ccgtcaggac cgccacctgt gtgtcttcca tccgcgcact
    12001 ccgcttctgt cgctcctggg gcatggcagg ggggccgctc acggggcggc cgccgggacg
    12061 accgggccct gctcgccgcc ctgtttggcg gccacgaacg cggcgatgct ctcgacggtg
    12121 cggaagcggt caggggacag gtcgccggtt gccacaccga tgccgaactc cctctccagc
    12181 gccacgaaca ggtgcatgaa gccgatggag tcgagcaggc cggtgccgat caaatcgatg
    12241 ccgggggccg gcggatcgat atggaggacg tcgcccagca ggcgggcgac gcggtctgtc
    12301 atcccggagg ggtcgttcat cgggtgctcc cggagttcgg tcggggcgag tcaggggtcg
    12361 ccggtgtgcg ggggccgtgc acgccgtccg cggtgtcggt gccggccagt cggttcgcga
    12421 gttcccggcg caggaccttg ccggtccggg tcctcgggat cgcgtcgagc agttccacgc
    12481 gacggggcag gaccccgggc cggaacgccg cggccagcgc gggccgtacg tcaggagggc
    12541 cttgggcgcc ggaggcgggc accaccgccg ccacgatctc ctcgcccagg aagcggtgcg
    12601 ggagcgccgc gcacgcggcg tcgcggacct ggggatgggc gcgaagcacc cggtccatct
    12661 cgtccaggga gacggtctcg cccccgacct tggcgatgtt cttgcggcgt ccggtgatga
    12721 cgatgaaggg cccgtcgcag tccgggtcgg tgacctcaag ccccaggtcc tgggtatgga
    12781 accagcctcc cgcgaacgcc tccgccgtcg cgtgcgggtt ggcttcgtag cgggacatca
    12841 cgttgtggcc gcgcacgcag atctcgccca cctgcccggg agttgcccgc gtcccctccg
    12901 gcgtcagcac cgccacctcg ttgccgtaca gggccgtgcc gatcgagggg atgtcggtgt
    12961 ccagcatcag ccgccggtac gcgtcctcgg acaggtcggc cggcagcgtc gtcgagaagt
    13021 tcaccgtctc ggtcagcccg tagccctgga gcacccgggc gccgaagcgg tcccgcaccg
    13081 cccgtgcggt ccgcacggtc aagggcgccg cggcggagac gaagtacccg aaatccgcgg
    13141 ggagttccgg ctgcctccag gtctccagga gggcttccag gacactcggg acgacgctgg
    13201 cgatccgcgg ccggaaccgc tggagcagcc gggggtagcg cagcggcgcg aagccgtccg
    13261 cgagcaggac gtgggcgccg gccgccagga cgccgaggac ggtgaagtgc agaccgttga
    13321 cgtggtggac gggaaggcag ccgagcaacc ggtcaccggg gcgcagcccg tggtggcgcc
    13381 cgagggcctc cgcgttcacg gcggcgttgt agtgcgactg ggcgaccagt ttggcggccg
    13441 cggtcgatcc ggaggtggcg aagaacaggg cgtcctgagc cgggtcgagc accgggtcgg
    13501 cgtccggtcc ggccgggtcc gccagggtgc ccggatcggg gatcacgacc gcctccggca
    13561 gcgcctcggc ggggacggcg ggagagcgga ggaccacctg tgcccgtgcc gcctcggcct
    13621 gttgccgtct gcggtcggca gggtcctgcg ggccgagcag gagcagcgca cagcccgccc
    13681 gtaggacgcc caggagggcc acgaccgaga cggggtcgtt ggccggggcg agggccacgg
    13741 tccggccggg ggcgatgtcg agttcggccc gcagccagcg cgccacgcgc cggctcagca
    13801 cgtcgagttc accgtaggtg agcgtgctgg gttcgccgtc gcccgacacg gtcgtcagga
    13861 agggggcccc gccccgggtc cgggcgtggt gcacgagcca ggacaccacg gtggggtgcg
    13921 gggtcagccg gtcctcgaag gggatgccgc ggtaggtgtg ggcgcgctcg gcgtcggtgg
    13981 gggacgaaga gaccatcact cacccgaacc ggtgggggga gtgcgtgcag cccttcgccg
    14041 ccagctcctc gccgccggcc gctgagatgt cgcagagccg gcaggtgatc tcgcccagct
    14101 cgccgaggag cgcggcgtag gccgtcagct cctgccggtc ggggctgtcg aggcggcggt
    14161 gcggtgcgcc cacggagaga atcatgtggt cggtgaccgc gcccacggcg tgggtgatgt
    14221 cgccctggac catgtacacc tggccgggcc gggtgcgcac gatctccccg gccaccgcga
    14281 tcgtcccggt gcccgcgagc acgaacaaca ggtggtcccc cgggtgggtg tgcggggcga
    14341 agccgctgcc cgccggcaca tggaggatgt cggcccccac atgtccgctg gaggccaggg
    14401 agtgtccggt ggcgtcggcg gtcttcgtca ccttcgtcgg accgggcgcg acctcgatgc
    14461 cgagctgttg cgtcgtaccg tccagcccga ggtcggcggc ccagtcacag atcagcaggg
    14521 ggccgggttt ggtgtcgggt gcctcgggcc gctcctcggg ctggagcgcc tcggccttgg
    14581 cgcgtccgaa caccgcgagc agctcgaccg tcttggcctg gcgctcggcg gggtcgaggt
    14641 cgtgcagctc ctcggtcagc atggcgatga cctgctgcgt ggacatgccc tctgtcgtct
    14701 cgatcatggc gtctctccgt cgtgtcgggg ggtgggggcc gggtcggggc gccggtccgc
    14761 caggaagggc gcccgcccca ggtgttgggc gaggtagcag gaaaggggag cggcgaacac
    14821 gtggtagaga agcggtgaga actcctcgcg tacgcgcccc gtcacgggca gcgccgccca
    14881 gctgtgccgg gcgaggccgg tgtcgtcctc gggcgcgacg gcgatcaccc gccgcccgag
    14941 cgccgccgcc ttcgcggcga cctccacggc gtgccggtac gagcgccccg gcgcggccac
    15001 cacgaccatc ggcatgtcgg ccgggcgggc gaaccgttcg acgtggcacc actcctccag
    15061 gtcctgcccg gtggcgaaga ccccggaggt ctcgatcacc ttggcggcgc cgaacagcgc
    15121 ggtgccatag gaggggccgc tgccgaccac ggtcagcacg ggggcgccgg cgatccgctc
    15181 ggccggctca cggcaccgct cgcgggccgc ctcggcggtc gcctcgaccg gtccggccag
    15241 cgcggtgagt tcgccccgca gcgcgtccgc ctcctgccgg gtgagccgct cgcgcgcctc
    15301 gcccagccgg atggcgatca acaacagccc caacaggctt gcctggtagc tgcggacacc
    15361 cggcgaccgc tcggtgcgcg gcagcgtcac caggagggcg ccgtcgctcg cgccggcgag
    15421 cgcgctgccg gacgtcgcgg tgaccgcgac ggcggtcgcc ccggcctcgc gagcccgttc
    15481 cgccgaccgc acgacgagcg gggtgcggcc cgaggcggag accgcgagcg tcaactccgt
    15541 acgcgacggg cggcagtcgg cgaaggggag gtcgtagtcc acaaaccgca gtgcgttcac
    15601 cgggcggcag tccacgcccg ccagcgacgc gaaggccatc tgcacggcac acgcggcgtg
    15661 gtaggagtcg ccgtctccca cgatggtgac ggagtccacc gccgcccacc gcgcggagag
    15721 gcgcgagcgg acctgttcgt cgaaggggcc ggtctgctcg cggaggtcct cggcgagtgc
    15781 tgccacctgc cgcagcatca cctgcgggtc cagcggaggc ggcgcctggc tcccggcggc
    15841 cgggccgttc ccgtcgctca tcgctccagc ctccgtacga tgtcgacgta ggccgcgacc
    15901 cggtcgcggt cgatctcgcc gccccagccg tcacgctcca ggcaggtgcc cacgaacgct
    15961 ccgtcggccg ctgccagcag tcgcgcggcg ttgtcgtgcc gggtgtggcc ggccaggatg
    16021 acgggcagat cgggaaccgc cttgcgcacc gcggcgatca tctccagggc cgtgtcctcg
    16081 tccgggtggc acagcgacac cgcgtccgca ccgaccgcgc gggcggcccg cgcgacctcg
    16141 gcggtggact tctccccgcc gaaccaccgg aagtgcatcg agtcgatctc ggcgacgatc
    16201 cgcacgtccg tggcgccgat ccggcggcgg taggccatca cctccatcgg atcgggccgg
    16261 accatgccgt gcggggtgag ggtctgcccc accagggcgc ccgcccggat gtagctgccg
    16321 ccggccacct tcgccaccgc cagggacggc gtcagcgcgt tgcgcatcag ctgcacgccg
    16381 atgtggaacc gctcgtccgt ggcctcggcg accgcccgca cgatcaggcc catcgccacg
    16441 gtgcgggccg gatcggacac gtcgtcgacg cggtacaccc ggtccaccgt ctggatgagg
    16501 cagccgtcgg ccccgccctc gtacagcgct cgcgccgaac ggaccgcggt gtcgcgcacc
    16561 cggtcgaacg atccgtcctc gtggaacggg gtgccgggca gcggtgacag gtgcaccatg
    16621 cccaggacca gtttgtggcc gccaggggcc gtccatccgt ccatgggtca gctccccgtc
    16681 gtgcggccgg cgtgcgaccg cagtcggtcg atggcgggtg cgagctcgtc ccaggaccgc
    16741 gccgtggtga cccggacgac gccgccggag aggcagaacg tgaggatccc ggggaagacg
    16801 gagacaccgg tctcccgcag aatgtcgcgg aaacatcggt aggagtcgtc ccagccgggg
    16861 aactcgacgg cggtgttgat ggagaagcgc ggagggagca ccagcccgga ggtctccgcc
    16921 agccggaccg tggccgcgtc ccgcaggacg gtcaggtcct cggcgcgccg cagccgctcg
    16981 gtgcgatagc cgcggtaggc gttccgcagc tgggcgaggt ccatgctgta ggacgcctcg
    17041 aactccttgg cctcggccgg ccccggcacc tcgacccccg tgatgagcca ccgctccagg
    17101 cgcgcgagca cctcgatgac cgtgtagaag aacgagggcg gcccgccgaa ggaggacgac
    17161 gcgtactcgt agtactcgtc gatgaacgcc ggatcggcga ggaaccaccc ggccttgagg
    17221 cccggcgccg accaggactt ggagaggctg gagacgcgta ccacgttggg ggccgcgcgc
    17281 tcgggggacc gctcctcgta ggtgcccagc cattcgtggc actcgtccag cacgatgatc
    17341 gtggaggggg aggcggcgcg gatcagccgg gccagctccg actcggtcac ggcggcgccg
    17401 gtcggattcc ccacggtctg caacatgacc agcggggtgt cgggggtgag cgcggcgatc
    17461 accggatcga ccgaggtctg cccgccctcg gaggcgaggg gcaccagctg cacctcatgc
    17521 cggcgggcga ccgactccac caggggcgga tagttgggga tcgcgcacag cgccggggag
    17581 gaggaccggg ggccgtcgtg cagcacgaag tcggcgagcg tgctgatcgc gaaggtgccg
    17641 cccatggtga tggcgacatt cgctgcgccg tacctcgccc ccgtgatgcg ggcgttctcg
    17701 tacgcggcga tggcctcgcg ggccggaacg cgcccgcgcg agtcggagta gccgtaccag
    17761 tcccggtcga gggcgtagcg gatgcactcc ttcagactct gcggcaggcc ccacttctcc
    17821 tcgtcgatcg acccgctgga gaggatgtag cgggcgttgt cccgcagttc gccgtagaga
    17881 tcgtcacgga agaacgagtt gaagagctcc ttgacgaagc ggacggtcgc ccgggaggag
    17941 agcacttcct cggcaccgac cgtgcgccgc ggccggctgg cgcgccagcc ctcggcgagc
    18001 tcagggcgca gggcgtgcgc cccgagttcg tgctcgaccc gccccagcca caggtcccgc
    18061 agctccaggg ggtcgtgggg gtcgcgtgcc cgggcgtaca cctccaggac acgctcgtct
    18121 atgccgggtg tgaagacgtc gcggacgcca ccgggttgcg gtgcgcgcgc ggcggtctcg
    18181 cgtgcgtcct gcggggtgta ccgcggacgc ggagacggaa gggattcgaa gagtttcatg
    18241 cgtttcccga gtgggccgcc ccaaagggcg agggcgaatg gagggcatgg gcgcgggcgg
    18301 gctgatccgg aagacggaca ggcctagacg atgcgcagac gcttgaggtg ccgcagccgg
    18361 gcctcgggcg ctgccgaacc ggccgttctc ccgtggaaga agtaggtgtt gtcgatgacg
    18421 acgagcagtc cgcgccgcca gtggaccgcc cgggcgtgcc ctggtgcgta catcgccgcc
    18481 agcaggtcgc ggagcgcgtc gttgacggcc acggcgtcgc cctcaggtcc ctcgcgggtc
    18541 cagtggagtt cgtcggtcag gaagtcgcgg aaggagaaca cccagcggtc cccggccttc
    18601 cgggcgatcg tcggtacgcc ggggtggtga cggtagcggg tgcgcgagag gacgtcggtg
    18661 gtccgcggcg ccacccggcg cgccacgtcc cgcatcggta cgagcaccgt ccgggcgccc
    18721 tgcgaggcgt ccccgggggc gacgcacatc agcacgatgt agcgcggctg cctttcgacg
    18781 gggccgccac tgctctcggt gtgcagcgac aggtagttcc ccgcgaaggg ctgcaacgac
    18841 acgtcgtcgg tgcgccggtg ctcgctgcgg aggttgagga tcacctcgtc ctccacgtac
    18901 gggcggaccg ccgggtcccg ctcgggcatg gccgtgccga ggaaggcccc gagcgcggtg
    18961 aaccggtcgt tcggcagcgg ctcgtcgagc tggaccgcgg ccaggccacg gcgccacagc
    19021 tggtccgaca cctccgcatg gagggcgtcg tgcgggccgg tcgccggtcc gggccggggg
    19081 gcgaggtcgc gcagcggcgt gccgtttccc aacgtccgct cgcgcagcgg tacatggggg
    19141 tcgtccgcgg cggtcaggaa ggttccgtgg gtcaccccgc ccccgggttc ccgcggtgcc
    19201 gcgggccggg tgggggaggt gggggatcgc tgttccatgg caaatgctcc tggtggggtc
    19261 agccgcagtg cgccggacgt acggagcggg tgcgctccgc ccagccgacg gcgggtttca
    19321 tggccaggct cgcgaggatg aacaggccgc cgagcagcag ccagccgacg gcgccgccct
    19381 ggacgacggt gagcgtgagg aacgaggggg cgatcatggc cgccgtcgca tatccggtga
    19441 agaagaaccc ttggtactgc ccctgcatgt ccgccggtgc caggtcgaat ccgatgaccc
    19501 aggcgccggc cgacaacacc atctccccgt agacgtgcac ggcaccggcc agcaccagga
    19561 acgtcaccgc tgcggccacg ctgtccgtcg ccgatgccgc gaacagcgca caggcgacgc
    19621 acagcacgat tccggcccgc aggacggccc gcacggcgag cggcacctgc gtcacccgct
    19681 tcgcgatccg cacctggaac gccaccacgc tcaccgtgtt gagcaggaac aacaccgtca
    19741 ccagccaacg cggggcggcg gtatgcgtgg cgatccacag cgggaccacg atctccagca
    19801 gcaccgcatg cagcgacagc accgcggtca gtgcggtgac cagggcgaag ggccggtcgc
    19861 gcaggacggc cagccggggg cgcccggcat cctcgtcgga cgcgggcttc ggcgccaccc
    19921 gcggcagccg cgtcagcacg cccgcggcca cgaggaagaa cagcgcgtcc agcaccagca
    19981 cggtgcggaa ggcggcgggg gtgttcacct gaagggctat gccggccagg cccgccccca
    20041 ccgccacacc cgcattggtg accgcgcgca gatacgcccg ggtctccacc aggtccccgc
    20101 cgtccagggt tcccgcgacc gctgcctgga gagccgcccg gctgcctcgc tccagcatga
    20161 cgaacaggca ggccgacacg gtgaattgga cgaaggaacc gacgaccagg tagcccgccg
    20221 ccgccacgcc gttcgcggcg gtcagcagcg ccgccgtccc ccgaggcccc cggcggtcgg
    20281 ccagatgccc cagcggaacg ccggcgaaca ggcccaccgc cccggcgagg gtcagaccga
    20341 gccccaactg ggtcacggaa atcccgacca cggtggtgaa atagagagcg gagcaggtca
    20401 tgaacgcgcc ttggcccagc gtgatgaaca gggtagccac ggccagaacg cgtcccggtc
    20461 cggaagcggg gagaattcgg ttcagcac
//
