BGC0001925: altemicidin biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 20,488 nt. (total: 20,488 nt).
This entry is originally from NCBI GenBank LC420052.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001925
Short description altemicidin biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
LC420052.1
via
Compounds
  • altemicidin
  • SB-203207
  • SB-203208
Species Streptomyces sp. [taxonomy]
References
Chemical products information
altemicidin [synonyms: (-)-Altemicidin, (-)-Artemicidine] Evidence:
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C13H20N4O7S1
Chemical database entries
PubCHEM
SB-203207 Evidence:
(no structure information available)
SB-203208 Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BBG06550.1
  • sbzA
 1 - 3102 (+) Ile-tRNA synthetase-like enzyme
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    • BBG06551.1
    • sbzB
    		 3122 - 4720 (+) adenylate-forming enzyme
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      • BBG06552.1
      • sbzC
      		 4717 - 5757 (+) acyltransferase
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        • BBG06553.1
        • sbzD
        		 5857 - 6861 (-) methyltransferase
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          • BBG06554.1
          • sbzE
          		 6905 - 7687 (-) N-methyltransferase
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            • BBG06555.1
            • sbzF
            		 7743 - 8705 (-) 4,5-dihydropyridine reductase
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              • BBG06556.1
              • sbzG
              		 8750 - 9007 (-) acyl carrier protein
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                • BBG06557.1
                • sbzH
                		 9057 - 10061 (-) mutarotase
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                  • BBG06558.1
                  • sbzI
                  		 10061 - 10627 (-) GNAT N-acyltransferase
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                    • BBG06559.1
                    • sbzJ
                    		 10630 - 12024 (-) aldehyde dehydrogenase
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                      • BBG06560.1
                      • sbzK
                      		 12039 - 12320 (-) acyl carrier protein
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                        • BBG06561.1
                        • sbzL
                        		 12317 - 13996 (-) AMP-binding enzyme
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                          • BBG06562.1
                          • sbzM
                          		 14000 - 14686 (-) cupin dioxygenase
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                            • BBG06563.1
                            • sbzN
                            		 14704 - 15861 (-) isomerase
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                              • BBG06564.1
                              • sbzO
                              		 15858 - 16664 (-) BtpA like enzyme
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                                • BBG06565.1
                                • sbzP
                                		 16668 - 18239 (-) aminotransferase
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                                  • BBG06566.1
                                  • sbzQ
                                  		 18324 - 19238 (-) alpha-ketoglutarate-dependent dioxygenase
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                                    • BBG06567.1
                                    • sbzR
                                    		 19259 - 20488 (-) MFS family transporter
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                                      Biosynthesis information
                                      Annotation changelog

                                      Entry version: next

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2024-03-19
                                      MIBiG v4 annotathon
                                      • (ID: Q4G2APLPZNOU4XV72H6GYP54)
                                      • (ID: D5UIALNVPDWCMADVVDHBCS3X)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 3

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-10-07
                                      Update chemical activity to schema version 2.11
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 2

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-09-15
                                      Cleaned up synonym list
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2022-09-15
                                      Fetch compound properties from PubChem
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2022-09-15
                                      Updated bioactivity data
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2022-09-15
                                      Added AMP-binding domain substrate specificities
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 1

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2019-10-16
                                      Submitted
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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