BGC0001926 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001926 (Talaromyces verruculosus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	28,006	chrodrimanin B	PKS	100%

BGC0001926 - Region 1 - T1PKS

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Location: 1 - 28,006 nt. (total: 28,006 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 28,007
Label		BGC0001926

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001926	1.00	Polyketide	chrodrimanin B	Talaromyces verruculosus
BGC0000146	0.30	Polyketide	solanapyrone D	Alternaria solani
BGC0002155	0.30	Polyketide	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15
BGC0002525	0.30	Polyketide	fusarubin, 1233A, 1233B, NG-391, lucilactaene	Fusarium sp.
BGC0002194	0.29	Polyketide	epipyrone A	Epicoccum nigrum
BGC0002191	0.28	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0002515	0.28	Polyketide	solanapyrone A	Ascochyta rabiei
BGC0001899	0.28	Polyketide	abscisic acid	Leptosphaeria maculans JN3
BGC0001252	0.28	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0000012	0.27	Polyketide	alternapyrone	Alternaria solani

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001926	1.00	Polyketide	chrodrimanin B	Talaromyces verruculosus
BGC0000146	0.64	Polyketide	solanapyrone D	Alternaria solani
BGC0002155	0.63	Polyketide	nectriapyrone C, nectriapyrone D, nectriapyrone	Pyricularia oryzae 70-15
BGC0002525	0.63	Polyketide	fusarubin, 1233A, 1233B, NG-391, lucilactaene	Fusarium sp.
BGC0002194	0.63	Polyketide	epipyrone A	Epicoccum nigrum
BGC0002191	0.62	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0002515	0.62	Polyketide	solanapyrone A	Ascochyta rabiei
BGC0001899	0.61	Polyketide	abscisic acid	Leptosphaeria maculans JN3
BGC0001252	0.61	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0000012	0.61	Polyketide	alternapyrone	Alternaria solani

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 28006:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

cdmE

PKS_AT (588..906): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 61.0
Methylmalonyl-CoA: 60.9
Isobutyryl-CoA: 41.7
Ethylmalonyl-CoA: 35.6
Malonyl-CoA: 34.8
Propionyl-CoA: 33.5
Benzoyl-CoA: 22.3
fatty_acid: 15.4
CHC-CoA: 10.3
trans-1,2-CPDA: 9.3
2-Methylbutyryl-CoA: 9.1
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0