LOCUS       BGC0001928              8550 bp    DNA     linear   BCT 16-NOV-2014
DEFINITION  Streptomyces sp. MA37 fluorinated carboxylic acid gene cluster.
ACCESSION   BGC0001928
VERSION     BGC0001928
KEYWORDS    .
SOURCE      Streptomyces sp. MA37
  ORGANISM  Streptomyces sp. MA37
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 05:25:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8550
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..8550
                     /db_xref="taxon:1400207"
                     /isolate="MA37"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. MA37"
     subregion       1..8550
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001928"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..8550
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(109..1362)
                     /gene="orf1"
     CDS             complement(109..1362)
                     /codon_start=1
                     /gene="orf1"
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 66.5; E-value: 3.7e-20)"
                     /gene_kind="transport"
                     /product="MFS family"
                     /protein_id="CEG06576.1"
                     /transl_table=11
                     /translation="MTAYDDRPSTHTGDGSGTHRPARPFRTVAFGVGAVLAANSTPTPL
                     YVTYQERWGFSAGTLTTVFAVYAAGVLAALLLVGGLSDRIGRRPVLQGSLCALIASYAL
                     FLAADGVTWLYCARAVQGLATGVFTGAAGAALADLHPRADHRTAGLVNSAAMPSGLAVG
                     ATVSGALAEWGPAPLRSPFLVLAGVSLVVLAAISAWVPETVAAPGRQWSRVVRLQPLRV
                     PPEARREFLVAAMGVAVAWAVGGLYLGLAGSLVKELLHGSDSFVAGLVILSMQGVAGAA
                     QLTWALRWSTVPDRVASAVGCAALCLGILAVASALFTGSPVLFFAGSAVTGVGFGLAFM
                     GSSRRITQAAPLARRGETLAAFFVVAYLAFSVPSVLAGLLTTRFGLVHTFYLFAETTAL
                     LSAATAVRSVRLDAIHLS"
     gene            1551..2189
                     /gene="fdrE"
     CDS             1551..2189
                     /codon_start=1
                     /gene="fdrE"
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 117.8; E-value:
                     6.7e-36)"
                     /gene_kind="regulatory"
                     /product="LuxR family regulator"
                     /protein_id="CEG06577.1"
                     /transl_table=11
                     /translation="MVLAHPNSLYRQGITALLSTDAGFSVVGQAGDGDHCIETVEREQP
                     DVVLIDCSIPGPPLETVIARIGALTPRTRTMVLLARRDDPGLLRRLVRLGVRAFLVPDG
                     DRDELRSAVRMVVNSGDRVVMSIPRDMMRGLGESGRLLSRREVEVLRLVAKGLTNSEVG
                     VTLFIAEGTVKRHLTNIYTKLGVRSRIQAVNKAFVLGVMGDRGGVSSHG"
     gene            2182..3039
                     /gene="fdrD"
     CDS             2182..3039
                     /codon_start=1
                     /gene="fdrD"
                     /product="Cyclase"
                     /protein_id="CEG06578.1"
                     /transl_table=11
                     /translation="MADGSPESDRIASPPWAGGYEIVDLSVLVAEDMPCYWPTHQPYQA
                     KVWNWYEDRQDVASAPLYSREGPYATRWLALDEHTGTHFDAPSHFIPHEDSGLPNAGEW
                     GAVSADRVPLSRLNGPAAVVDVSALTGSAGEAAVSPLVTVDHITAWEDAHGELAPGDVV
                     LFRSGWDSRYRRGPAGRAYAHDVVVTRCGDAWPAPDVATIELLLDRGVRCAGIDAPSIA
                     PVQGKLPVEVHVTGLGAGAVFVEGLAGLDALPPRGAWFCFLPVKLEGATGAPGRAVAWV
                     PRAR"
     gene            complement(3091..3876)
                     /gene="fdrC"
     CDS             complement(3091..3876)
                     /NRPS_PKS="Domain: PKS_KR (16-176). E-value: 2e-13. Score:
                     42.4. Matches aSDomain: nrpspksdomains_fdrC_PKS_KR.1"
                     /codon_start=1
                     /gene="fdrC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     236.6; E-value: 4.9e-72)"
                     /gene_kind="biosynthetic-additional"
                     /product="short chain dehydrogenase"
                     /protein_id="CEG06579.1"
                     /transl_table=11
                     /translation="MSPAPELRPGRLSGKSAVVTGAARGIGRATALRFAREGALLTLTD
                     VDGKALGELAAELTAQGTEPATVAGDVSVPADAERMIAAAVEAYDRLDVLVANAGILPL
                     IRITDASADDWDHVMAVDGRGMFLTCKFAIERMAAAGGGAIVCLSSISGLAGQAGQSTY
                     GPAKFVATGLTKHLAVEWADRGIRVNAVAPGTIRTDRVRRLPDEPGGAAYLAEIERRHP
                     MGRIGEPDEVAAAIVFLASDEASFVTGAVLPVDGGYLAQ"
     aSDomain        complement(3349..3828)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_fdrC_PKS_KR.1"
                     /evalue="2.00E-13"
                     /label="fdrC_PKS_KR.1"
                     /locus_tag="fdrC"
                     /protein_end="176"
                     /protein_start="16"
                     /score="42.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="AVVTGAARGIGRATALRFAREGALLTLTDVDGKALGELAAELTAQ
                     GTEPATVAGDVSVPADAERMIAAAVEAYDRLDVLVANAGILPLIRITDASADDWDHVMA
                     VDGRGMFLTCKFAIERMAAAGGGAIVCLSSISGLAGQAGQSTYGPAKFVATGLTKH"
     CDS_motif       complement(3379..3441)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fdrC_0002"
                     /evalue="3.10E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="fdrC"
                     /protein_end="166"
                     /protein_start="145"
                     /score="19.7"
                     /tool="antismash"
                     /translation="VCLSSISGLAGQAGQSTYGPA"
     CDS_motif       complement(3760..3825)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_fdrC_0001"
                     /evalue="6.20E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="fdrC"
                     /protein_end="39"
                     /protein_start="17"
                     /score="15.7"
                     /tool="antismash"
                     /translation="VVTGAARGIGRATALRFAREGA"
     gene            complement(3873..5579)
                     /gene="fdrB"
     CDS             complement(3873..5579)
                     /codon_start=1
                     /gene="fdrB"
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="CEG06580.1"
                     /transl_table=11
                     /translation="MAGSRPSRANPILTGPDRAAARAALRATGLSGRELAQPMIGVAHS
                     WIGTMPCNLNHRVLAEAAMHGVRSAEATPLEINTIAISDVITMGTVGMRTSLVSREVIA
                     DSIELVGRGHALDGLVTLVGCDKTIPAAAMAHVRLDIPGVIVYSGTTLPGRFRGEDVTV
                     QDVFEGVGRHAAGELDDAGLAELERSACPGAGACGGHYTANTMAMAMEFLGLSPFGSMD
                     PPTGDPRKSDACRDAGVLAARLVEDGLAPSAILSKDSFRNAITACAATGGSSNLVLHLL
                     AIAAESGIPLDINEFDAISSRTPLVADLRPSGRYTAVDLDIAGGTRLVGRRLLEAGLLA
                     GDALTVTGRSLADEVAEAAERPGQQVIAPAGAPFAPSSGLVVLRGNLAPEGSVLKTTGT
                     GTRRLTGPAVVFDSEELAMSAVQSGAITEGDVVVIRYEGPRGGPGMREMLGVTAALVGR
                     GLGPSVGLVTDGRFSGATLGLMVGHVAPEAADGGPLAALRDGDLVTIDLDGRVVDVDLS
                     PVELSQRLKEWEAPPSRCPAGVMAKYRDTVSSAALGAITTRPRSHGRTEQP"
     gene            5825..6625
                     /gene="fdrA"
     CDS             5825..6625
                     /codon_start=1
                     /gene="fdrA"
                     /product="Phosphoesterase"
                     /protein_id="CEG06581.1"
                     /transl_table=11
                     /translation="MRVLYIGDVVGTDAAELLVRKIEDMRRAYGVDLVLVNAENCAPDG
                     FGTTVEQLERLLAAGVDVICGGNHSWDSPQAVASLDLPRVLRPANVEDGAPGRGVLTVE
                     AAGTTVTVVNLADACAMHSARGVADKFFPAYRAWRSAEKQGAVIVDYHGDHVLEKQIFA
                     HAVDGEAAAVLGSHTHEPTIPLHFLPGGTVLVTDVGMTGPVGGVQGFDPTHLVRNLRER
                     GNPFAGELPVPVAGAPITLGAVVMSIVGNRTVKAERLDDAVLTG"
     gene            6643..7446
                     /gene="fdrF"
     CDS             6643..7446
                     /codon_start=1
                     /gene="fdrF"
                     /product="Ribulose 5-phosphate 4 epimerase"
                     /protein_id="CEG06582.1"
                     /transl_table=11
                     /translation="MTEPTGGTFAASLTPRDPELPGPPEFATVEEERRHRREQLAIAFR
                     IFGKFGYGEHLAGHITVRDPELHDHFWVNPLGRSFSRIRMSDLILVNADGLVVHGDAPV
                     NKAAFAIHSQLHHARPDIVAAAHSHSLYGKALAALGQPLLPITQDACLFFEDNVVVPDF
                     QGIVYDPAEGARIAKQLGTMSTAILANHGLLTVGRSVEEAATLYVQAERAAQVQLIAAA
                     AGELRPIDPEVARFTYSQTGLQGQNWRGFLPLREEILHEQPDVLQ"
     gene            complement(7476..8402)
                     /gene="fdrG"
     CDS             complement(7476..8402)
                     /codon_start=1
                     /gene="fdrG"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 191.2; E-value:
                     3.6e-58)"
                     /gene_kind="transport"
                     /product="ABC transporter"
                     /protein_id="CEG06583.1"
                     /transl_table=11
                     /translation="MHDLERLFADAEKWTVPEGGRPVPDRLSLIRFENVTFSYPDSNDN
                     DNDNSDKATERPALDGVTLDIPVGKIVALVGENGSGKTTVSKLLAGLYQPTGGRILWDG
                     VDACELDRARLWSMFAMVGQDFHRWPFTCRMNVAIGRPERPVQQAALEDAAAYAGADSV
                     VEELPRGWDTLLKKGYKGGHQISGGQWQRLGIARARYRDAPVLIVDEPTSALDAKAEAE
                     VFEQIRRLADTGQTVVLITHRLASVRYADLIHVLEDGRLRESGSFTELLAPSSTGVFRE
                     LYEMQRAQFENPALPGRRKPADAGHGS"
ORIGIN
        1 gttcacggtc gtggagaagg cctacatgct gccgaagaac agcccgctca ccggacaggc
       61 cgacgactgg ctggcgacag ccgtgtcgga cggcaccttc caggcgtact acgacaggtg
      121 gatggcgtcg agccgtacgg aacggaccgc ggtggcggcg gagagcagtg ccgtggtctc
      181 cgcgaagagg tagaacgtgt gcaccaggcc gaaccgggtg gtgaggaggc ccgccagcac
      241 agaaggaacg gagaacgcca ggtaggcgac gacgaagaac gcggccaggg tctccccgcg
      301 ccgcgcgagc ggagcggcct gggtgatgcg gcggctgctg cccatgaacg cgagaccgaa
      361 tccgacgccg gtcaccgccg acccggcgaa gaacagcacc gggctgcccg tgaacagggc
      421 actggcaacg gccaggatgc cgaggcacag cgcggcgcag ccgaccgccg aggcgacccg
      481 gtccggcacg gtgctccagc gcagggccca ggtcagctgg gcggctccgg cgacgccctg
      541 catgctcagg atcaccaggc cggcgacgaa ggagtccgac ccgtggagca actccttgac
      601 caggctgccc gcgaggccca ggtacagccc tccgaccgcc caggcgacgg ccacccccat
      661 cgcggcgacg aggaactcgc ggcgtgcctc gggcggcacc cgcagcggct gcaggcgtac
      721 cacccgtgac cactgccgcc cgggcgcggc gaccgtctcg gggacccagg cgctgatcgc
      781 cgcgagcacg acgagcgaga cgccggcgag cacgaggaag ggggagcgca gcggcgccgg
      841 cccccactcg gccagcgcgc cgctgaccgt ggcccccacc gcgaggccgc tcggcatggc
      901 ggcgctgttc accagcccgg cggtccggtg gtcggcgcgg gggtgcagat cggccagggc
      961 cgcaccggcc gcaccggtga acaccccggt cgccagcccc tggacggcgc gggcgcagta
     1021 gagccaggtc accccgtccg cggcgaggaa cagcgcgtaa ctcgcgatca gcgcgcagag
     1081 gctgccctgc aggaccgggc ggcgcccgat ccggtcggac agcccgccga cgagcaggag
     1141 cgccgccagg accccggccg cgtagacggc gaagaccgtg gtgagcgtgc cggcggagaa
     1201 gccccagcgc tcctggtagg tgacgtacaa cggcgtgggg gtgctgttcg cggccaggac
     1261 cgcgccgacg ccgaaggcca cggtccggaa ggggcgtgcg ggccgatggg tgccgctgcc
     1321 gtccccggtg tgcgtggacg gtcggtcgtc gtacgcggtc atgcagccgt cctcacgtcc
     1381 ggagcgtcgg cggtggcggg caggtgtatc acccaatgaa cttctccggc atccctcaag
     1441 ttcccccgat ctaaaggggg ttgaggcttg actgtgcgga tcggcgcgag tatttgtacg
     1501 tcgtcgagcg atgggggcgt cccgtttccg agaatcaaga gtgcatcagc atggtcttgg
     1561 ctcaccccaa ctccctgtac cggcagggaa tcaccgcgct gctgagcacg gatgccggct
     1621 tctccgtcgt ggggcaggcg ggcgacgggg accactgcat cgagacggtg gagcgcgagc
     1681 agccggacgt cgtgctcatc gactgcagca ttcccggccc gcccctggaa accgtgatcg
     1741 cacgcatcgg cgcactgacc ccgcgcacca gaaccatggt cctgctggcc agacgcgacg
     1801 accccggcct gctgcggaga ctggtccgcc tcggggtacg ggcgtttctg gtgcccgacg
     1861 gtgaccgcga cgaactccgc tccgccgtac ggatggtggt gaacagcggc gaccgggtcg
     1921 tcatgtcgat cccccgggac atgatgcgcg gcctcggcga atccggccgg ctgctctccc
     1981 ggcgcgaggt cgaagtgctc cgcctcgtgg cgaaaggcct gacgaacagc gaggtcggag
     2041 taacgctctt catcgccgaa ggaacggtga aacggcatct gaccaacatc tacacgaagc
     2101 tcggcgtgag atcgcggatc caggccgtca acaaggcttt tgtgctggga gtgatgggag
     2161 acagaggagg tgtttcgtcg catggctgac ggatccccgg agagcgaccg gatcgcctcg
     2221 ccgccgtggg ccggagggta cgagatcgtc gacctctccg tactggtggc cgaggacatg
     2281 ccctgctact ggcccaccca ccagccgtac caggcgaagg tgtggaactg gtacgaggac
     2341 agacaggacg tcgcctcggc cccgctgtac agcagggaag gcccgtacgc aacccgctgg
     2401 ctcgccctcg acgaacacac cgggacccac ttcgacgcac cctcccactt catcccgcac
     2461 gaggactcgg ggctgccgaa cgcgggggag tggggcgcgg tgtcggcgga ccgggtcccg
     2521 ctgtcccggc tcaacggccc cgcggccgtc gtcgacgtct cggcgctgac gggctcggcc
     2581 ggggaggcgg ccgtcagccc cctggtgacg gtggatcaca tcaccgcctg ggaggacgcg
     2641 cacggcgaac tggcccccgg tgacgtggtg ctgttccgct ccggatggga ctcccgctac
     2701 cgccgcggcc cggccgggcg ggcgtatgcg cacgacgtcg tcgtcacccg gtgcggcgac
     2761 gcctggcccg cacccgacgt cgccacgatc gaactgctcc tggaccgcgg cgtccgctgc
     2821 gcgggcatcg acgcccccag catcgccccc gtgcagggaa agctgcctgt cgaggtgcac
     2881 gtgacgggcc tcggcgccgg cgcggtcttc gtcgaggggc tcgccggcct ggacgcactg
     2941 cccccgcgcg gcgcctggtt ctgcttcctt cccgtcaagc tggaaggggc aacgggcgcg
     3001 cccggccggg ccgttgcctg ggtgccccgc gcgcggtgaa gcggctccgg cccgccgtcc
     3061 gggaccgggg cggcggactg gaaccgccgc tcactgcgcc aggtacccgc cgtccacggg
     3121 cagcaccgcc ccggtgacga acgaggcctc gtccgaggcg aggaagacga ttgcggccgc
     3181 gacctcgtcc ggctcgccga tcctccccat cgggtgcctg cgctcgatct cggcgaggta
     3241 cgcggcgccg cccggctcgt ccggcagccg gcgcacccgg tcggtacgga tcgtccccgg
     3301 cgccacggcg ttgacccgga tgccccggtc cgcccactcc accgcgaggt gcttggtgag
     3361 cccggtggcc acgaacttcg ccggcccgta ggtgctctgg cccgcctggc cggcgagccc
     3421 ggagatggac gacaggcaca cgatcgcgcc gccgccggca gcggccatcc gctcgatggc
     3481 gaacttgcag gtgaggaaca tgcccctgcc gtcgaccgcc atgacgtggt cccagtcgtc
     3541 cgcggacgcg tccgtgatcc tgatcagcgg caggatcccg gcgttggcga cgagcacgtc
     3601 cagccggtcg tacgcctcga ccgccgccgc gatcatccgc tcggcgtccg cgggcaccga
     3661 cacgtccccg gccaccgtgg ccggttcggt gccctgcgcg gtcagctccg cggccagttc
     3721 gccgagggcc ttcccgtcca cgtcggtgag ggtcagcagc gcgccctccc gggcgaagcg
     3781 cagggcggtg gcgcgtccga tgccgcgggc cgcgcccgtg acgaccgccg acttgccgga
     3841 caaccggccg ggcctgagct ccggggccgg gctcacggct gctccgtccg gccgtgtgag
     3901 cgcggacggg tggtgatcgc gcccagcgcc gccgaggaga cggtgtcgcg gtacttggcc
     3961 atcaccccgg ccgggcaccg ggacggcgga gcctcccatt ccttcaggcg ctgggagagc
     4021 tcgaccgggg acagatccac gtcgaccacc cggccgtcca ggtcgatggt cacgaggtcg
     4081 ccgtcccgca gggcggcgag cggcccgccg tcggcggcct ccggcgccac atgacccacc
     4141 atcagaccca gggtggcccc ggagaaccgg ccgtcggtga ccagccccac cgagggcccc
     4201 aggccccggc ccaccagggc ggccgtgaca ccgagcatct cgcgcatccc cggaccgccg
     4261 cgcgggccct cgtaccggat caccacgacg tcgccctcgg tgatggcgcc ggactgcacc
     4321 gcgctcatcg cgagttcctc ggagtcgaag accaccgcgg gccccgtcag cctgcgcgtg
     4381 ccggtccccg tggtcttgag gacggagcct tccggcgcca gattgcccct gagcacgacc
     4441 agccccgacg acggggcgaa cggtgcaccg gcgggcgcga tcacctgctg gcccggccgc
     4501 tcggcggctt cggccacctc gtcggcgagc gaacgtcccg tcaccgtcag ggcgtccccg
     4561 gccagcagcc ccgcctcgag gaggcgccgg ccgacgagcc gggtgccgcc cgcgatgtcc
     4621 aggtcgacgg cggtgtaccg gccgctgggc cgcaggtcgg cgacgagcgg ggtgcgggag
     4681 ctgatcgcgt cgaactcgtt gatgtccagc gggatgccgc tctccgcggc gatggccagc
     4741 aggtgcagga cgaggttgga cgagccgccg gtggccgcac acgcggtgat cgcgttgcgg
     4801 aaggagtcct tgctcaggat cgcgctcggg gcgagaccgt cctccaccag gcgggccgcg
     4861 agcaccccgg cgtcccggca ggcgtcggac ttgcgcgggt cgccggtggg cggatccatc
     4921 gagccgaacg gcgacagacc gaggaactcc atggccatcg ccatggtgtt ggccgtgtag
     4981 tgccccccgc acgccccggc tccggggcag gcgctgcgct ccagttcggc gagccccgcg
     5041 tcgtcgagct caccggccgc atgacggccc acgccctcga agacgtcctg cacggtgacg
     5101 tcctcgcccc ggaaacggcc gggaagtgtc gtaccggaat agacgatgac accgggaatg
     5161 tcgaggcgca cgtgggccat ggccgcggcc ggaatggtct tgtcgcaacc caccagcgtg
     5221 acaagcccgt cgagtgcatg accccggccg acgagttcga tggaatcggc gatcacctcg
     5281 cggctgacca gcgaggtgcg catgcccacg gtgcccatgg tgatgacatc cgatatggca
     5341 atggtgttga tttccagcgg agttgcctcg gccgacctga ccccgtgcat ggccgcctcg
     5401 gccagcacac ggtggttgag attgcacggc atcgtgccga tccagctgtg cgcgacaccg
     5461 atcatcggct gggccagttc cctgccggac aggcccgtcg cacgcagcgc cgccctggcc
     5521 gccgcccggt cggggcccgt cagtatgggg ttggcccggg aaggacgaga tcccgccatc
     5581 gcatccaccc tccgtttctg ggagggcgct caccctaatc gctcggcctg cgcacggaac
     5641 gagtcggccg gagggcaaaa caaagaatcc gcttacgtgg cagacgcggt gtgccgaagg
     5701 tcgtagcgcg tgaatgtgac gatggtggga tgcggctcct catggccctg ggcagagttg
     5761 aatgacctga tcggggcagc acagcacagc gaaggcgggc tggactacct ttgggggcgg
     5821 ccgggtgaga gttctctaca tcggtgacgt cgtgggaacg gacgccgcgg aactcctcgt
     5881 acgcaagatc gaggacatgc gccgggcgta cggcgtggac ctggttctgg tcaacgcgga
     5941 gaattgcgct ccggacggat tcggcacgac cgtggagcag ctggaacggc tcctcgccgc
     6001 cggggtcgac gtcatctgcg gcggcaacca ctcctgggac agcccgcagg ccgtggcctc
     6061 gctcgacctg ccgcgggtcc tgcgccccgc caacgtcgag gacggcgccc ccggacgcgg
     6121 cgtcctcacc gtcgaggcgg ccggcaccac ggtgaccgtg gtgaacctcg ccgacgcctg
     6181 cgccatgcac tccgcgagag gcgtggccga caagttcttc cccgcctacc gggcctggag
     6241 gtcggcggag aaacagggcg cggtcatcgt cgactaccac ggtgaccacg tcctggagaa
     6301 acagatcttc gcgcacgccg tcgacggcga ggccgcggcg gtgctcggca gccacacgca
     6361 cgagccgacc attcccctgc acttcctgcc gggcggcacc gtactggtca ccgacgtggg
     6421 catgaccggc cccgtcggag gcgtccaggg cttcgacccg acacacctgg tgcgcaacct
     6481 gcgcgaacgg ggaaacccct tcgccggcga actccccgta cccgtcgccg gagcaccgat
     6541 caccctcggc gcggtggtga tgagcatcgt gggcaacagg accgtcaagg cggaacggct
     6601 ggacgacgcc gtgctgaccg gatgagcagg agaggcccca ggatgaccga gcccactggc
     6661 ggaaccttcg ccgcgtccct cacaccccgc gacccggaac tgcccggccc gccggagttc
     6721 gccaccgtgg aggaggaacg ccggcaccgc agggaacaac tcgccatcgc cttccggatc
     6781 ttcggaaaat tcggctacgg cgaacacctg gccggacaca tcaccgtgcg tgacccggaa
     6841 ctccacgacc acttctgggt gaaccccctc ggtcggtcct tctcccggat ccggatgtcc
     6901 gacctgatcc tcgtcaacgc cgacggactc gtcgtccacg gcgacgcgcc cgtgaacaag
     6961 gcggccttcg ccatccactc ccaactgcac cacgcacgcc cggacatcgt cgcagccgca
     7021 cacagccact ccctctacgg aaaggccctc gcggcactgg gacaacccct gctccccatc
     7081 acccaggacg cctgcctgtt cttcgaggac aacgtcgtcg tacccgactt ccagggcatc
     7141 gtgtacgacc cggcggaagg cgcccgcatc gccaaacagc tcggcaccat gagcacggcc
     7201 atcctcgcca accacggcct gctcaccgtg ggccgcagcg tggaggaagc ggccaccctc
     7261 tacgtccagg ccgagcgcgc ggcgcaggtc cagctcatcg cggcggcggc aggtgaactc
     7321 cggcccatcg accccgaggt ggcccggttc acctacagtc agacggggct gcagggccag
     7381 aactggcgcg gattcctgcc gctgcgggag gagatcctcc acgagcagcc ggacgttctg
     7441 cagtgagcgc ggccgctcgt cagcactcgg cgatgtcatg acccgtgccc cgcatcggcg
     7501 ggcttgcgcc ggccgggcag cgcggggttc tcgaactggg cgcgctgcat ctcgtacagc
     7561 tcgcggaaca ccccggtcga cgacggggcg agcagttccg tgaacgagcc ggactcccgc
     7621 agcctgccgt cctcgaggac gtggatgaga tcggcgtacc gcacggaggc cagacggtgc
     7681 gtgatcagca cgactgtctg cccggtgtcc gcgagcctgc ggatctgctc gaagacctcc
     7741 gcctcggcct tcgcgtcgag cgcggaggtc ggttcgtcga cgatgaggac cggggcgtcg
     7801 cggtagcggg cgcgggcgat cccgagacgc tgccactggc cgccggagat ctggtgcccg
     7861 cccttgtagc ccttcttcag cagggtgtcc cagccccggg gcagctcctc caccaccgaa
     7921 tcggcgcccg cgtacgcggc ggcgtcctcc aatgccgcct gctgcaccgg gcgttcgggg
     7981 cggccgatgg cgacgttcat gcggcaggtg aacggccacc ggtggaagtc ctggccgacc
     8041 atcgcgaaca ttgaccacag ccgggcccgg tccagttcgc aggcgtcgac gccgtcccac
     8101 aggatccggc cgccggtcgg ctggtacagg ccggccagca gcttggagac ggttgtcttg
     8161 cccgagccgt tctcgccgac cagtgccacg atcttcccga ccgggatgtc cagcgtcacg
     8221 ccgtccagcg cggggcgttc cgtggccttg tcgctgttgt cgttgtcgtt gtcgttgctg
     8281 tcggggtagg agaacgtgac gttctcgaag cggatgagcg acagccggtc ggggaccggg
     8341 cgcccgcctt cggggacggt ccacttctcg gcgtccgcga agaggcgctc caagtcgtgc
     8401 acgtagcagg cctgttcgta caacgcgcag gacgagcgtg gacaggctct gcccgccggt
     8461 gcggacggcg agcacggcgg tgccggccac cgacagggcc atcagcccgg tggcgagcag
     8521 gccgcccagt gccgcgtagg tcagcagggc
//
