LOCUS       BGC0001929              4678 bp    DNA     linear   BCT 17-JUN-2018
DEFINITION  Streptococcus ferus strain NCTC12278 genome assembly, chromosome: 1.
ACCESSION   BGC0001929
VERSION     BGC0001929
KEYWORDS    .
SOURCE      Streptococcus ferus
  ORGANISM  Streptococcus ferus
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 05:25:30
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4678
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[242:2424]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      243..2424
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..4678
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..4678
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001929"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..4678
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            243..1106
                     /locus_tag="NCTC12278_00563"
     CDS             243..1106
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /inference="ab initio prediction:Prodigal:2.60"
                     /inference="similar to AA sequence:RefSeq:YP_006043434.1"
                     /locus_tag="NCTC12278_00563"
                     /product="transcriptional regulator"
                     /protein_id="SQF39783.1"
                     /sec_met_domain="TIGR01716 (E-value: 1.6e-51, bitscore:
                     163.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFGEIFKTFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTIS
                     KFMAILDEINMPIDEFMYTVHDFHRDELNELLSKVRHFVSNHDIEGLKRLLYSQMESDP
                     KQEKFHKLNIVLLKIRLQDLSGESYYSSDDLSYLTDYLFSVEYWGYYELLIYSNTLDVL
                     KHDVFMVLAREMSRRSDFYREIPNNRRLISSMLLNGYITCVERGKFIDALYFKKQLNQC
                     FFTETEIYERLVFQYAQHLYRYKKESDCKAIIEMRKCIAAMKLVGSNHLAQTYERHLEK
                     VLGENS"
     gene            1306..2424
                     /gene="moaA"
                     /locus_tag="NCTC12278_00564"
     CDS             1306..2424
                     /codon_start=1
                     /gene="moaA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="ab initio prediction:Prodigal:2.60"
                     /inference="similar to AA sequence:RefSeq:YP_002745277.1"
                     /locus_tag="NCTC12278_00564"
                     /product="radical SAM protein"
                     /protein_id="SQF39785.1"
                     /sec_met_domain="PF04055 (E-value: 1.4e-24, bitscore: 75.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5e-13, bitscore: 38.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.8e-16, bitscore:
                     46.8, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.5e-13, bitscore: 39.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDYSPYPLLVDVCVTNRCNLNCSYCSAEAGPFASKKGEMSVEKL
                     DSVFRELDLMGVPRVGVTGGEPFMREDILDILKAFDQYRFAKVLNTNGNLITDSIAREL
                     SKLNLDRICVTIDGSKSSVHDSQRGKGSFKKAIEGIKNLQRYNLPVSTLFTLGKHNVDD
                     LINTIRLNDMLGIEYMSVMVICPTGRANDGSILADKKHWYPVFLSLTEQLSRGEFKVKF
                     KIVPPNESDVFWTHYFPLAFYNRLDLLESVWHQKVDVNFDKPREISCQAGVRACSINHK
                     GDVYGCDLMNGIDELVAGNVKEQKFSEIWHNSVIFNKLRSITFDDISGKCAECPLPWCG
                     GGCRCSALELDGTLLGSDLACFYEQQRDMEVV"
     gene            2421..2741
                     /locus_tag="NCTC12278_00565"
     CDS             2421..2741
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="ab initio prediction:Prodigal:2.60"
                     /locus_tag="NCTC12278_00565"
                     /product="Uncharacterised protein"
                     /protein_id="SQF39787.1"
                     /sec_met_domain="PF05402 (E-value: 1.3e-12, bitscore: 36.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.8e-13,
                     bitscore: 38.3, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="Streptide_RRE (E-value: 2.3e-40, bitscore:
                     125.6, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEHFVIKGKRDFIVNKVADEYIGYDRLDLEYYSFDEIGAEILYC
                     ISKNFSLDKIVELLKQDYEVSEDECKQAIISFLEETPILHIIYANLVKSDIYLQLKPFR
                     EK"
     gene            2741..4003
                     /locus_tag="NCTC12278_00566"
     CDS             2741..4003
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 108; E-value: 8.3e-33)"
                     /gene_kind="transport"
                     /inference="ab initio prediction:Prodigal:2.60"
                     /inference="similar to AA sequence:RefSeq:YP_002745275.1"
                     /locus_tag="NCTC12278_00566"
                     /product="multi antimicrobial extrusion (MATE) family
                     transporter"
                     /protein_id="SQF39789.1"
                     /transl_table=11
                     /translation="MIDSKEMNRFAVPLVLTNIGQIIIGQLALHFAVNNSSIVLSGISI
                     IQNMLFAFGGLLGAFSLSFNIKSSKAYSNRQYSKFNDLLKSNLIINLIIGTAFAFFVIF
                     YGETMLSRLYGFRGSLLALATNYLVIMSPYIILTLLNFSLTNLLRVQKETRPIMWIGLA
                     SSLLDVLLNYILVPLFGIRGAAISTIVSLCFVTCSYLFMVYPMIWKSIFVKSTTKLELV
                     KSGIPLAGQEVLESVLFIIVFDAFMARLGLEILAIYAVISQLLSIIRVPSFVYSTTVSV
                     YLPEAEKMGHVKEFLKTIFKNSYAASMLLACPVVLLSNILSHFLSDEITTNVVPIALYT
                     FLAMGISPIYESSKMLLQSFGNEKFVLHVSILINLASVMILTILQLLKVQTYLSLYFIY
                     GLNLFVLSLIFLRHASSEKFI"
     gene            4111..4677
                     /locus_tag="NCTC12278_00567"
     CDS             4111..4677
                     /codon_start=1
                     /inference="ab initio prediction:Prodigal:2.60"
                     /inference="similar to AA sequence:RefSeq:YP_006489856.1"
                     /locus_tag="NCTC12278_00567"
                     /product="ATP-dependent RNA helicase"
                     /protein_id="SQF39792.1"
                     /transl_table=11
                     /translation="MLNKMKARLLIGLGGLVVSSFIVMMGYTIGSQSVTNHTHKQIQSE
                     AHNLLTKEKEKEKASVLSDELVKEFLTQYYTKEKLAAEFSPEELAQYILALTVQDPDMM
                     PAVEIAREKPLPFKPSGGGFKGKSGNKRGRNDRRGGRDRDRREGGFKRTSNKNRRDFEN
                     KSNKRPHRTSSEKKNGFVIRNKGDK"
ORIGIN
        1 ctgaactgca ccccaaaagt tagatagaaa aaatctaact tttggggtgt tatttttatg
       61 aaattatatg cattctggag actaaccaac aacaataata ataattcctt taagaaatag
      121 gaataataaa agtagttttt gctttttcat gtgaaatacc tcacttttat ttttttccta
      181 ttttatgcta aaatgttaca aaacaaaaaa tattcccata tatgcgtaat ggaggaagtg
      241 agatgaaaaa ttttggagaa atttttaaaa cctttcgaga atcaagggga ttacgattaa
      301 aagatgtcgc aaaagctggt atatcaacgt ctcagctttc acgtttcgaa aaaggagaga
      361 cggatttaac catttcaaaa tttatggcta ttttagatga gattaatatg cctattgatg
      421 aatttatgta tacggttcat gattttcatc gtgatgaatt aaatgaactc ttatcaaagg
      481 ttcgccattt tgtatctaat catgatattg agggattgaa aagattactc tattcccaaa
      541 tggagtcaga tcctaagcag gagaaatttc ataaacttaa tatcgtttta ttaaaaattc
      601 gtttacaaga tttatcagga gaatcttatt attctagtga tgatttatct tatctaaccg
      661 attatctttt tagtgttgaa tattggggat actatgaatt attgatttat tcaaatactt
      721 tagatgtcct aaaacatgat gttttcatgg ttttggctag agagatgtct agacgttctg
      781 atttctacag agaaattcca aataatagac gattgatttc atcaatgtta ttaaacggat
      841 atattacatg tgttgaaaga ggaaaattta ttgatgcttt gtattttaaa aagcaattaa
      901 accaatgttt tttcactgaa actgaaattt atgagcggtt ggtgtttcag tatgcacaac
      961 atctatatcg atacaaaaaa gagtcggatt gtaaagcaat tattgaaatg agaaaatgta
     1021 ttgcagctat gaaattagta ggaagtaatc acttagcaca gacttatgaa agacatttag
     1081 aaaaagtttt aggagagaat agctagtcag cagatatggg aaaactttcg atacttattt
     1141 caaaaagata taattgagtt atcaaattaa ggaggaaaga cctatgtcac ctaaaaaaga
     1201 gtttaatgct cctaagacaa ctaaagttaa tagttggggt aagcattaag aaagtaccta
     1261 taggtcaaca tttgttgacc tataggtttt taggaggaaa aataaatgag agattattcg
     1321 ccatatccat tattagtaga tgtttgtgta accaatcgct gtaacttaaa ttgttcctat
     1381 tgttctgcag aagctggtcc ttttgcaagt aaaaaaggag aaatgagtgt agaaaagtta
     1441 gattctgttt ttagagagct tgatttgatg ggagttccta gagtaggtgt gactggtgga
     1501 gaaccattta tgcgtgagga cattcttgac atcttgaaag cttttgatca atataggttt
     1561 gctaaggttt tgaatacgaa tggaaactta atcacagact ctattgctag agaattatca
     1621 aaactgaatt tagacagaat ttgtgtaacg atagatggta gtaaatctag tgtacacgat
     1681 agtcaacgag gaaaaggaag ttttaagaaa gctattgaag gaataaaaaa tttacagcga
     1741 tataacttac ctgtttcaac actatttact ctaggaaaac ataatgttga tgatttaata
     1801 aatactataa gattgaatga tatgcttggt atagagtata tgtcagtaat ggtcatttgt
     1861 ccgaccggta gggctaatga tggtagtatt ttggcggata aaaaacactg gtatccagtt
     1921 tttctttctc taactgagca gctttctaga ggtgagttta aggttaagtt taaaattgtt
     1981 ccaccaaatg aaagtgatgt tttttggacg cattattttc cgcttgcatt ttataataga
     2041 ttggatttac tagaaagtgt ttggcatcaa aaagtagatg taaattttga taagccaagg
     2101 gagatatcat gtcaagccgg tgtcagagca tgttcaatca atcataaggg ggatgtatat
     2161 gggtgtgatt tgatgaacgg gatagatgag ttagtcgctg gaaatgttaa agaacaaaag
     2221 tttagtgaaa tttggcacaa ttcggttata tttaataaac taagatcaat tacatttgat
     2281 gatatttctg gcaaatgtgc ggaatgtccc ttaccatggt gcggtggtgg atgccgatgc
     2341 agtgctctgg aattggatgg aacattattg gggtctgatt tagcttgctt ttatgaacaa
     2401 caaagggata tggaagtcgt atgaaagaac atttcgtgat aaaaggtaag agagatttca
     2461 ttgtaaataa agtagcagat gagtatatcg gatacgatag gcttgattta gagtactatt
     2521 cgtttgatga aataggagca gaaatacttt attgcatttc caaaaatttt tctttggata
     2581 agattgtaga actgttaaag caagactacg aagtatctga ggatgagtgt aagcaggcaa
     2641 tcatatcttt cttagaagaa acaccaattt tacatattat ttatgcaaat ttagttaagt
     2701 ctgatatata cttacagtta aaacctttta gggagaaata atgatagatt caaaagaaat
     2761 gaatagattt gcagtgccgc tagttttgac taacattggt caaattatta ttggacagct
     2821 ggctttacat tttgctgtga ataactcatc aatagtttta tcgggaatct ctattattca
     2881 gaatatgcta tttgcttttg gtggcctttt aggagccttt agcctatctt ttaatattaa
     2941 aagttctaag gcttattcta atcgacagta cagtaaattt aacgatttgt tgaaatcaaa
     3001 tttaatcata aatttgatta ttggaacagc atttgctttt tttgtaattt tttacggaga
     3061 aacaatgctg agtagacttt atggatttag aggtagttta ttagcattag caacaaatta
     3121 tttagttatt atgtccccct atataatttt gacactatta aacttttccc ttactaatct
     3181 attgagagtt caaaaggaaa caaggccaat tatgtggatt ggattggcaa gctcactatt
     3241 agatgtatta ttgaattata tattggtacc actattcgga attagaggag cagctatatc
     3301 aacgattgta tctttgtgtt ttgttacttg tagctattta ttcatggttt atccaatgat
     3361 ttggaagtct atatttgtga aatctacaac gaaattagag ttagtaaaat ctggtattcc
     3421 attagctggt caagaggttc tagaaagtgt gctatttatt atagtgtttg atgcatttat
     3481 ggcaagacta ggtttggaga tacttgcgat ttatgctgtt attagtcagc tactttcaat
     3541 cattcgtgtc ccttcttttg tatattcgac aacagtttcc gtttatttgc ctgaagcaga
     3601 gaaaatggga catgtcaaag aatttttgaa aactatattt aaaaattcat atgctgctag
     3661 tatgttactt gcttgtcctg ttgttttatt atcaaatatt ctatctcact ttctttctga
     3721 tgaaataaca acaaatgttg tacctattgc tttgtataca tttttggcta tggggatatc
     3781 tcctatttac gaaagttcta aaatgttact acaaagcttt ggaaatgaaa aatttgtttt
     3841 gcatgtatct attttaataa atcttgctag tgttatgatt ctaaccatat tacaattatt
     3901 aaaagttcaa acctatttat cgttatactt tatatatggg ttgaatctat ttgttttgtc
     3961 tttgatattt ttacgacatg cttcttcaga aaaatttata taaaaaagat ttagtcttaa
     4021 attacggcta aatctttttt gtgataactt ttccaggtca atcttgttat gatggtgcta
     4081 tcttacgaaa aaaaggagat agcattatct atgttaaata aaatgaaagc gaggcttttg
     4141 attggtttag gaggtctagt ggtgtctagt ttcattgtaa tgatgggcta taccattggt
     4201 tctcagtctg tgactaatca cacgcataaa caaatccagt ctgaagctca taacctattg
     4261 accaaagaga aagaaaagga aaaggcaagt gttctctctg atgaactggt caaggaattt
     4321 ctaacgcaat attacaccaa ggaaaagctg gcggcggaat tctcaccaga agagttagcg
     4381 caatatattt tggccttgac cgttcaagat cctgatatga tgccagctgt tgagattgcc
     4441 cgtgaaaaac ctttgccgtt caagccatca ggaggcggct tcaaaggcaa gagcggcaac
     4501 aaacgcggcc gtaatgatcg tcgtggcggc agagaccgtg atcgcagaga aggcggcttt
     4561 aagcggacct ctaataaaaa ccgcagagat tttgaaaata aatccaataa acgcccgcat
     4621 cgtacctcaa gcgagaagaa aaacggcttc gttattcgca ataaaggtga taaataaa
//
