BGC0001937: tubercidin biosynthetic gene cluster from Streptomyces tubercidicus
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Location: 4,367 - 12,776 nt. (total: 8,410 nt).
This entry is originally from NCBI GenBank MG706975.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001937
Short description tubercidin biosynthetic gene cluster from Streptomyces tubercidicus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
MG706975.1
4367 - 12776
via
Compounds
  • tubercidin
Species Streptomyces tubercidicus [taxonomy]
References
Chemical products information
tubercidin Evidence:
Copy SMILES
C11H14N4O4
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AVW83008.1
  • orf-1
 4367 - 4543 (+) (2Fe-2S)-binding protein
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    • AVW83009.1
    • tubA
    		 4810 - 5187 (+) 6-Pyruvoyltetrahydropterin synthase
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      • AVW83010.1
      • tubB
      		 5587 - 6006 (+) Radical SAM family protein
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        • AVW83011.1
        • tubC
        		 6007 - 6606 (+) GTP cyclohydrolase I
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          • AVW83012.1
          • tubD
          		 6623 - 7780 (+) Guanosine monophosphate reductase
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            • AVW83013.1
            • tubE
            		 7777 - 8361 (+) Phosphoribosylpyrophospate transferase
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              • AVW83014.1
              • tubF
              		 8358 - 9626 (+) UbiD family decarboxylase
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                • AVW83015.1
                • tubG
                		 9667 - 10173 (+) Nudix hydrolase
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                  • AVW83016.1
                  • tubH
                  		 10121 - 11065 (-) Carbohydrate kinase family protein
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                    • AVW83017.1
                    • tubI
                    		 11255 - 12379 (+) MFS transporter
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                      • AVW83018.1
                      • orf1
                      		 12570 - 12776 (-) hypothetical protein
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                        Biosynthesis information
                        Annotation changelog

                        Entry version: 3

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-10-07
                        Update chemical activity to schema version 2.11
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Cleaned up synonym list
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Fetch compound properties from PubChem
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Updated bioactivity data
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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