BGC0001940: pyxidicycline A biosynthetic gene cluster from Pyxidicoccus fallax
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Location: 1,739 - 21,113 nt. (total: 19,375 nt).
This entry is originally from NCBI GenBank MH048639.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001940
Short description pyxidicycline A biosynthetic gene cluster from Pyxidicoccus fallax
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MH048639.1
1739 - 21113
via
Compounds
  • pyxidicycline A
  • pyxidicycline B
Species Pyxidicoccus fallax [taxonomy]
References
Chemical products information
pyxidicycline A Evidence:
(no structure information available)
pyxidicycline B Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AXM42912.1
  • pcyQ
 1740 - 2555 (+) ABC transporter ATP-binding protein
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    • AXM42913.1
    • pcyR
    		 2552 - 3334 (+) ABC transporter permease
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      • AXM42914.1
      • pcyS
      		 3360 - 4394 (+) ABC transporter transmembrane unit
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        • AXM42915.1
        • pcyT
        		 4391 - 5029 (+) pentapeptide repeat protein
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          • AXM42916.1
          • pcyP
          		 5080 - 5799 (-) hypothetical protein
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            • AXM42917.1
            • pcyO
            		 5832 - 8693 (-) glycoside hydrolase family 31
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              • AXM42918.1
              • pcyN
              		 9010 - 9771 (-) transcriptional activator TipA
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                • AXM42919.1
                • pcyM
                		 9841 - 10218 (-) hypothetical protein
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                  • AXM42920.1
                  • pcyL
                  		 10366 - 11082 (-) cyclase/dehydrase
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                    • AXM42921.1
                    • pcyK
                    		 11105 - 11407 (-) muconolactone delta-isomerase
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                      • AXM42922.1
                      • pcyJ
                      		 11410 - 13497 (-) AMP-dependent synthetase and ligase/heterocyclase
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                        • AXM42923.1
                        • pcyA
                        		 13680 - 14807 (+) metal-dependent hydrolase
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                          • AXM42924.1
                          • pcyB
                          		 14864 - 15715 (+) second ring cyclase/aromatase
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                            • AXM42925.1
                            • pcyC
                            		 15748 - 16710 (+) first ring cyclase/aromatase
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                              • AXM42926.1
                              • pcyD
                              		 16733 - 17530 (+) ketoacyl reductase
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                                • AXM42927.1
                                • pcyE
                                		 17578 - 18858 (+) beta-ketoacyl synthase alpha
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                                  • AXM42928.1
                                  • pcyF
                                  		 18855 - 20096 (+) beta-ketoacyl synthase beta
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                                    • AXM42929.1
                                    • pcyG
                                    		 20133 - 20369 (+) acyl carrier protein
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                                      • AXM42930.1
                                      • pcyH
                                      		 20426 - 20797 (+) holo-acyl-carrier-protein synthase
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                                        • AXM42931.1
                                        • pcyI
                                        		 20865 - 21113 (+) hypothetical protein
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                                          Biosynthesis information
                                          Annotation changelog

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Refined reference coordinates
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2022-09-15
                                          Added AMP-binding domain substrate specificities
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2019-10-16
                                          Submitted
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Detailed domain annotation
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