BGC0001945: chloromyxamide biosynthetic gene cluster from Myxococcus sp.
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 47,625 nt. (total: 47,625 nt).
This entry is originally from NCBI GenBank MH168382.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001945
Short description chloromyxamide biosynthetic gene cluster from Myxococcus sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
MH168382.1
via
Compounds
  • chloromyxamide
Species Myxococcus sp. [taxonomy]
References
Chemical products information
chloromyxamide Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AXM43045.1
  • orf1
 512 - 1948 (+) hypothetical protein
    copy AA seq
    copy Nt seq
    • AXM43046.1
    • orf2
    		 1945 - 2559 (+) hypothetical protein
      copy AA seq
      copy Nt seq
      • AXM43047.1
      • orf3
      		 2556 - 5939 (+) hypothetical protein
        copy AA seq
        copy Nt seq
        • AXM43048.1
        • orf4
        		 5936 - 7123 (+) putative cytosolic protein
          copy AA seq
          copy Nt seq
          • AXM43049.1
          • orf5
          		 7196 - 8479 (+) enolase
            copy AA seq
            copy Nt seq
            • AXM43050.1
            • orf6
            		 8564 - 9595 (-) hypothetical protein
              copy AA seq
              copy Nt seq
              • AXM43051.1
              • cmxA
              		 9781 - 10881 (+) Cyclization|Deamination
              • Cyclization
              • Deamination
              copy AA seq
              copy Nt seq
              • AXM43052.1
              • cmxB
              		 10980 - 21326 (+) non-ribosomal peptide synthetase
                copy AA seq
                copy Nt seq
                • AXM43053.1
                • cmxC
                		 21409 - 22665 (-) major facilitator family transporter
                  copy AA seq
                  copy Nt seq
                  • AXM43054.1
                  • cmxD
                  		 22878 - 23075 (+) hypothetical protein
                    copy AA seq
                    copy Nt seq
                    • AXM43055.1
                    • cmxE
                    		 23089 - 23952 (+) hypothetical protein
                      copy AA seq
                      copy Nt seq
                      • AXM43056.1
                      • cmxG
                      		 24028 - 24996 (-) methyltransferase type 11
                        copy AA seq
                        copy Nt seq
                        • AXM43057.1
                        • cmxF
                        		 25132 - 26256 (-) hypothetical protein
                          copy AA seq
                          copy Nt seq
                          • AXM43058.1
                          • cmxH
                          		 26517 - 28538 (+) putative chloroperoxidase
                            copy AA seq
                            copy Nt seq
                            • AXM43059.1
                            • cmxR
                            		 28631 - 30037 (-) aldehyde dehydrogenase
                              copy AA seq
                              copy Nt seq
                              • AXM43060.1
                              • cmxQ
                              		 30068 - 32245 (-) 3-hydroxyacyl-CoA dehydrogenase
                                copy AA seq
                                copy Nt seq
                                • AXM43061.1
                                • cmxP
                                		 32288 - 33499 (-) acetyl-CoA acetyltransferase
                                  copy AA seq
                                  copy Nt seq
                                  • AXM43062.1
                                  • cmxO
                                  		 33534 - 34682 (-) acyl-CoA dehydrogenase
                                    copy AA seq
                                    copy Nt seq
                                    • AXM43063.1
                                    • cmxN
                                    		 34712 - 35851 (-) acyl-CoA dehydrogenase
                                      copy AA seq
                                      copy Nt seq
                                      • AXM43064.1
                                      • cmxM
                                      		 35884 - 37722 (-) AMP-dependent synthetase and ligase
                                        copy AA seq
                                        copy Nt seq
                                        • AXM43065.1
                                        • cmxL
                                        		 37772 - 38599 (-) short chain dehydrogenase
                                          copy AA seq
                                          copy Nt seq
                                          • AXM43066.1
                                          • cmxK
                                          		 38596 - 39282 (-) TetR family transcriptional regulator
                                            copy AA seq
                                            copy Nt seq
                                            • AXM43067.1
                                            • cmxJ
                                            		 39279 - 40121 (-) enoyl-CoA hydratase
                                              copy AA seq
                                              copy Nt seq
                                              • AXM43068.1
                                              • cmxI
                                              		 40540 - 40956 (-) hypothetical protein
                                                copy AA seq
                                                copy Nt seq
                                                • AXM43069.1
                                                • cmxS
                                                		 41226 - 42233 (+) Zinc dependent alcohol dehydrogenasez
                                                  copy AA seq
                                                  copy Nt seq
                                                  • AXM43070.1
                                                  • orf7
                                                  		 42247 - 43791 (-) hypothetical protein
                                                    copy AA seq
                                                    copy Nt seq
                                                    • AXM43071.1
                                                    • orf8
                                                    		 43968 - 44483 (-) hypothetical protein
                                                      copy AA seq
                                                      copy Nt seq
                                                      • AXM43072.1
                                                      • orf9
                                                      		 44661 - 45563 (-) bifunctional protein FolD 1
                                                        copy AA seq
                                                        copy Nt seq
                                                        • AXM43073.1
                                                        • orf10
                                                        		 45632 - 47350 (-) B12 binding domain protein
                                                          copy AA seq
                                                          copy Nt seq
                                                          Biosynthesis information

                                                          Biosynthetic modules

                                                          Name
                                                          Unk01
                                                          Type
                                                          nrps-type1
                                                          Genes
                                                          cmxB
                                                          Substrates
                                                          valine (evidence: Structure-based inference, Feeding study, Sequence-based prediction)
                                                          Integrated Monomers
                                                          Domains
                                                          adenylation
                                                          Name
                                                          Unk02
                                                          Type
                                                          nrps-type1
                                                          Genes
                                                          cmxB
                                                          Substrates
                                                          pipecolic acid, proline (evidence: Structure-based inference, Feeding study, Sequence-based prediction)
                                                          Integrated Monomers
                                                          Domains
                                                          adenylation
                                                          Name
                                                          Unk03
                                                          Type
                                                          nrps-type1
                                                          Genes
                                                          cmxB
                                                          Substrates
                                                          hydroxyproline, proline (evidence: Structure-based inference, Feeding study, Sequence-based prediction)
                                                          Integrated Monomers
                                                          Domains
                                                          adenylation
                                                          Name
                                                          Unk04
                                                          Type
                                                          nrps-type1
                                                          Genes
                                                          cmxM
                                                          Substrates
                                                          glutamic acid (evidence: Structure-based inference, Feeding study, Sequence-based prediction)
                                                          Integrated Monomers
                                                          Domains
                                                          adenylation
                                                          Annotation changelog

                                                          Entry version: 2

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-09-15
                                                          Added NRP substrate specificities
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 1

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2019-10-16
                                                          Submitted
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          Similar known clusters from MIBiG 4.0
                                                          Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                          Detailed help and explanations are available here.

                                                          Click on reference genes to show details of similarities to genes within the current region.
                                                          Double click on a reference drawing to reverse the display of the genes.

                                                          Click on an accession to open that entry in the MIBiG database.


                                                          Location:

                                                          Identifier
                                                          Identity
                                                          Coverage
                                                          Detailed domain annotation
                                                          Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                          A domain glossary is available here, and an explanation of the visualisation is available here.
                                                          Selected features only
                                                          Show module domains