BGC0001950: puwainaphycin F biosynthetic gene cluster from Cylindrospermum moravicum CCALA 993
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Location: 1 - 57,756 nt. (total: 57,756 nt).
This entry is originally from NCBI GenBank MH325197.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001950
Short description puwainaphycin F biosynthetic gene cluster from Cylindrospermum moravicum CCALA 993
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
MH325197.1
via
Compounds
  • puwainaphycin F
  • minutissamide A
Species Cylindrospermum moravicum CCALA 993 [taxonomy]
References
Chemical products information
puwainaphycin F Evidence:
(no structure information available)
minutissamide A Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AXN93574.1
  • orf1
 1 - 1995 (-) ORF1
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    • AXN93575.1
    • puwA
    		 2075 - 10687 (-) PuwA
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      • AXN93576.1
      • orf2
      		 10864 - 15363 (-) ORF2
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        • AXN93577.1
        • puwB
        		 17074 - 24852 (+) PuwB
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          • AXN93578.1
          • puwc
          		 24856 - 26628 (+) PuwC
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            • AXN93579.1
            • puwD
            		 26797 - 27111 (+) PuwD
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              • AXN93580.1
              • puwE
              		 27423 - 36788 (+) PuwE
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                • AXN93581.1
                • puwF-G
                		 36785 - 54340 (+) PuwF-G
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                  • AXN93582.1
                  • puwH
                  		 54511 - 57756 (+) PuwH
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                    Biosynthesis information

                    Biosynthetic modules

                    Name
                    Unk01
                    Type
                    nrps-type1
                    Genes
                    puwA
                    Substrates
                    asparagine (evidence: Structure-based inference, Sequence-based prediction)
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk02
                    Type
                    nrps-type1
                    Genes
                    puwA
                    Substrates
                    proline (evidence: Structure-based inference, Sequence-based prediction)
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk03
                    Type
                    nrps-type1
                    Genes
                    puwE
                    Substrates
                    valine (evidence: Structure-based inference, Sequence-based prediction)
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk04
                    Type
                    nrps-type1
                    Genes
                    puwF-G
                    Substrates
                    threonine (evidence: Structure-based inference, Sequence-based prediction)
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk05
                    Type
                    nrps-type1
                    Genes
                    puwF-G
                    Substrates
                    asparagine (evidence: Structure-based inference, Sequence-based prediction)
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk06
                    Type
                    nrps-type1
                    Genes
                    puwF-G
                    Substrates
                    threonine (evidence: Structure-based inference, Sequence-based prediction)
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk07
                    Type
                    nrps-type1
                    Genes
                    puwF-G
                    Substrates
                    asparagine (evidence: Structure-based inference, Sequence-based prediction)
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk08
                    Type
                    nrps-type1
                    Genes
                    puwF-G
                    Substrates
                    alanine, serine (evidence: Structure-based inference, Sequence-based prediction)
                    Integrated Monomers
                    Domains
                    adenylation
                    Name
                    Unk09
                    Type
                    nrps-type1
                    Genes
                    puwH
                    Substrates
                    threonine (evidence: Structure-based inference, Sequence-based prediction)
                    Integrated Monomers
                    Domains
                    adenylation
                    Annotation changelog

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-10-07
                    Update chemical activity to schema version 2.11
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Updated bioactivity data
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Added NRP substrate specificities
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Submitted
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
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