LOCUS       BGC0001953             60901 bp    DNA     linear   BCT 22-AUG-2018
DEFINITION  Anabaena sp. UHCC-0399 puwainaphycin and minutissamide lipopeptide
            gene cluster, complete sequence.
ACCESSION   BGC0001953
VERSION     BGC0001953
KEYWORDS    .
SOURCE      Anabaena sp. UHCC-0399
  ORGANISM  Anabaena sp. UHCC-0399
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Anabaena.
REFERENCE   1  (bases 1 to 60901)
  AUTHORS   Mares,J., Hajek,J., Urajova,P., Kust,A., Jokela,J., Saurav,K.,
            Galica,T., Capkova,K., Mattila,A., Haapaniemi,E., Permi,P.,
            Mysterud,I., Skulberg,O.M., Karlsen,J., Fewer,D.P., Sivonen,K.,
            Tonnesen,H.H. and Hrouzek,P.
  TITLE     The structural diversity of cytotoxic puwainaphycin and
            minutissamide lipopeptides is generated by a common biosynthetic
            pathway employing two alternative starter modules
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 60901)
  AUTHORS   Mares,J., Hajek,J., Urajova,P., Kust,A., Jokela,J., Saurav,K.,
            Galica,T., Capkova,K., Mattila,A., Haapaniemi,E., Permi,P.,
            Mysterud,I., Skulberg,O.M., Karlsen,J., Fewer,D.P., Sivonen,K.,
            Tonnesen,H.H. and Hrouzek,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAY-2018) Institute of Hydrobiology, The Czech Academy
            of Sciences, Biology Centre, Na Sadkach 7, Ceske Budejovice 37005,
            Czech Republic
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Geneious Pro v. R10
            Sequencing Technology :: Illumina; Sanger dideoxy sequencing
            ##Assembly-Data-END##
            ##antiSMASH-Data-START##
            Version               :: 8.dev-5707d64f
            Run date              :: 2025-08-15 20:37:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start           :: 0
            Orig. end             :: 60901
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     region          1..60901
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..8565)
                     /gene="puwA"
     CDS             complement(1..8565)
                     /NRPS_PKS="Domain: Condensation_LCL (48-349). E-value:
                     1.7e-123. Score: 403.4. Matches aSDomain:
                     nrpspksdomains_puwA_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (514-915). E-value: 6e-111.
                     Score: 362.9. Matches aSDomain:
                     nrpspksdomains_puwA_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (1010-1230). E-value: 1.6e-124.
                     Score: 407.5. Matches aSDomain: nrpspksdomains_puwA_nMT.1"
                     /NRPS_PKS="Domain: PCP (1437-1505). E-value: 3.1e-25.
                     Score: 80.2. Matches aSDomain: nrpspksdomains_puwA_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1525-1826). E-value:
                     4.5e-123. Score: 402.0. Matches aSDomain:
                     nrpspksdomains_puwA_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1988-2384). E-value:
                     8e-112. Score: 365.7. Matches aSDomain:
                     nrpspksdomains_puwA_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2492-2561). E-value: 4.5e-28.
                     Score: 89.3. Matches aSDomain: nrpspksdomains_puwA_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2580-2843). E-value:
                     1.9e-40. Score: 131.6. Matches aSDomain:
                     nrpspksdomains_puwA_Thioesterase.1"
                     /codon_start=1
                     /gene="puwA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /note="NRPS; non-ribosomal peptide synthetase"
                     /product="PuwA"
                     /protein_id="AXN93605.1"
                     /sec_met_domain="AMP-binding (E-value: 4.7e-123, bitscore:
                     400.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4.7e-91, bitscore:
                     294.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.3e-17, bitscore:
                     52.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2e-40, bitscore:
                     129.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLLKRLDYLSPEQRELVLKKLQMQKTNSATDNNKSQSLPLVPV
                     DRNQAIPLSFAQQRLWFLDQLVGLSATYNTPTALQITGKLNINALEQAIIEIVRRHEVL
                     RTTFQEINNTPRQVVHPTVMVNLPVVDLQDLSDIEKASQVQQLVHQEAHKPFNLQQPPL
                     IRGQILRLDETSHVLLLTVHHIVVDGWSMGIFIQELSALYPAFATAKPSPLAELPIQYA
                     DFAVWQRQWLSGEVLETKLNYWRQKLAGAPPLLELPTDRPRPPIETFRGGSYTFTLSSQ
                     LTQQILSLSQKSGVTLFMTLQAAFVTLLHRYTSQDDILVGTPIANRNRQDIESLIGFFV
                     NTLVLRTKLNGNPKFSELLKQVQQVALEAYEHQDVPFEQVVEALQPERNLDHNPLFQVM
                     LVLQNAPQGTLKLLDLELTSIDINFATAKRDLTLTFVETDEGLGGVWEYNRDLFDESTI
                     IRIAEHLQTLLAAVVANPHQQIAYLPILTQAEQQQLLVEWNDTQKEYPTKLCLHQMFEA
                     QVELTPDAVAVLGNGEELTYGELNARANQVAHYLQSLGVEAEVLVGICAERSLEMVVGL
                     LGILKAGGAFVPLDPAYPRDRLQYLLEDSQVPVLLTQSHLLNILPEHQQVICLDTDWQA
                     ISQQSQANPVSQVKSTNLAYIIYTSGSTGKPKGTMIIHRGVVNYLSWCIEAYAVADGYG
                     APVQSSFAFDATITSLFSPLMVGRQVVLLPEKQEIEALCSVLQSKSQFSLVKLTPAHLE
                     LLNQIIPPAEAAGQTNAFVIGGEALLGKTLQFWRENAPQTRLINEYGPTETVVGCCIYE
                     VTDDTSLTEGILIGRPIANTQLYILDEYLQPVPIGVRGELYIGGAGVARGYLNRPELTK
                     EKFISHPFIHEPGARLYKTGDLARYQPDGNIEYLGRTDHQVKLRGFRIELGEIETAVNQ
                     HPEVRETVVITREDIPGDKRLVAYVVPNSQDSDRTDSSLANEFESEQLSQWQQVFNDSY
                     SQSATDSDPTFNIIGWNDSRTGLLIPKAEMREWVESTVDRILDWQPKQVLEIGCGTGML
                     LFRIAPQCDCYYGTDISPQALRYVQQQITQMGRDWSQVKLAQRSAENFHGVEQGGFDAV
                     VLNSVVQYFPSIDYLMQVLENAMQAIASAGFIFIGDVRSLPLLEAFHASVQLAQSLPSL
                     STGDLQQRIQRNLNQDSELVIDPAFFTALQQRFPQISHVQIQIKRGEYHNELTQFRYDV
                     TLHLGNAVTPKVVPQWLDWQQDQLTLPLLQDLLTKADVEILGVKNIPNARLKTEMRLLD
                     LLASLPENATVGELQRGLGTGDSLIDPEEFWRWEKELSLQVHISWSQTEKGNYDVVFVK
                     GNQNVLPIFEHSQTIEPWSNYGNNLLQGQLARKLIPQLRSFLKDKLPGYMIPNAFMLLP
                     VLPLTPNGKVDRVALPVPNLELSRTVSFVPPRTAEEEIIAAIIAEVLGLEEIGVYDNFF
                     ELGGHSLLATQVISRLQEAFPVELPLRCLFEAPSVVELDQFISNLRQGGTGLTATAITP
                     IPRTGEPLPMSWAQQRLWFLYQLEGASSTYNMPNVLQITGELQVNALKQTLSDIVQRHE
                     ILRTSFHLIDGNPVQVINTDASLSLEIIDLRELSNNQQQAAVEKFSNEEAQKPFDLNQA
                     PLVRATLLQLDANSHVLLFTLHHIVADGWSMGVIIQELSAMYPALAAGKLSPLPDLSIQ
                     YADFAVWQRQWLTGEVLETKLNYWQQQLADAPPVLELPTDKPRPAVQTFRGDRLAFQLR
                     KDFSEQLNLLSQQAGATLFMTLQAAFVTLLHRYTGQDDILVGTPIANRNRKELEPLIGF
                     FVNTLVLRNKVADNPKFSELLNQVKQVALDGYAHQDVPFEQIVEALQPERKLSHAPLFQ
                     VMFILQNAPMGNLELPGLSFVPLASENVTAKFDLTLSIWETKQGLAGWWEYNSDLFEPE
                     TISRMIAHFQTLLAGIVAHPEERIAQLPLLTEAEQQQLLGDGTTYAIEESIPELLATQV
                     QLTPDHIAVVFGEKQLTYAELDTRANQLAHYLQTLGVQPEVAVGICIERSLDLVVGLLA
                     ILKAGGAYVPLDSTYPGDRLAYMLQDSQAAVLLTTSNLVEIFPTHTAQVVCLDAVSWDN
                     LPSHIPVSGLTSDNLAYVIYTSGSTGKPKGVAMPHSALVNLLQWQINHTSIAANAKTLQ
                     FAPVSFDVSCQEIFATWCAGGTLVLLPEDTRKDTIALFNLLSEEGVERLFLPFVALQQL
                     AEVSANVESLPPLREIITAGEQLQVTPALKNFLQRLGNCTLHNQYGPSETHVVTAFTLS
                     DDVEEWPMLPPIGQAIANTQTYILDKYLQPVPMGVRGELYIGGVGVARGYLNRPELTAE
                     KFITHNQAKLYKTGDLARFLPDGNIEYLGRLDNQVKVRGFRIELGEVEAALNHHPHVKQ
                     AIVVVQGETSTEKRLIAYVVFNSEQQATPSELRHFLQQQLPEYMMPSVFVALDALPLTP
                     SGKVDRRSLPSPNGINPSQLAVAPRDSLELQLTQIWSEVLGVKWVGIRDNFFEIGGHSL
                     LAVRLMAQIQQKLHKQLPLASLFQNPTIEELANLLRQSTDASLWSSLVPIQTNGINPPF
                     FCIPGAGGNVLYFYDLARCLGAEQPFYGLQAQGLDGESEPLHRIEEIATEYIKAIQTVQ
                     PQGPYLLGGHSFGGLVAFEMAQQLQQQGHEIGLLAILDTIAPVRSERSRKIELDDAMWL
                     MQVAKVMERLFNTTLQLDYETLQPLSAETQLDYLLEQLKIAQILPTDASKIQLRGFVQV
                     YKTHTQAFSNYFPSLVNNTPITLFRASEVHEEEQAIAEYVNRLQDLTLGWNNFSDEPVD
                     IHIVPGTHLTMMQPPHVQVLAEHLQACIRGAIFDCK"
     source          1..60901
                     /collected_by="Matti Wahlsten"
                     /country="Finland"
                     /db_xref="taxon:2303154"
                     /isolation_source="Jurmo, Southwestern Archipelago National
                     Park, copepods"
                     /mol_type="genomic DNA"
                     /organism="Anabaena sp. UHCC-0399"
                     /strain="UHCC-0399"
     misc_feature    1..60901
                     /note="puwainaphycin and minutissamide lipopeptide gene
                     cluster"
     subregion       1..60901
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001953"
                     /subregion_number="1"
                     /tool="antismash"
     cand_cluster    1..60901
                     /SMILES="NC(C(O)C)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(C(O)C)C
                     (=O)NC(CC(=O)N)C(=O)CC(=O)NC(C(C)C)C(=O)C(C)CNNC(CC(=O)N(C)
                     )C(=O)N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..60901
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:58709]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..58709
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..57657
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[18458:37657](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      18459..37657
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     aSDomain        complement(37..825)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_Thioesterase.1"
                     /evalue="1.90E-40"
                     /label="puwA_Thioesterase.1"
                     /locus_tag="puwA"
                     /protein_end="2843"
                     /protein_start="2580"
                     /score="131.6"
                     /tool="antismash"
                     /translation="PFFCIPGAGGNVLYFYDLARCLGAEQPFYGLQAQGLDGESEPLHR
                     IEEIATEYIKAIQTVQPQGPYLLGGHSFGGLVAFEMAQQLQQQGHEIGLLAILDTIAPV
                     RSERSRKIELDDAMWLMQVAKVMERLFNTTLQLDYETLQPLSAETQLDYLLEQLKIAQI
                     LPTDASKIQLRGFVQVYKTHTQAFSNYFPSLVNNTPITLFRASEVHEEEQAIAEYVNRL
                     QDLTLGWNNFSDEPVDIHIVPGTHLTMMQPPHVQVLAEHLQ"
     aSModule        complement(37..3990)
                     /complete
                     /domains="nrpspksdomains_puwA_Condensation_LCL.2"
                     /domains="nrpspksdomains_puwA_AMP-binding.2"
                     /domains="nrpspksdomains_puwA_PCP.2"
                     /domains="nrpspksdomains_puwA_Thioesterase.1"
                     /final_module
                     /locus_tags="puwA"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(571..645)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0025"
                     /evalue="6.10E-15"
                     /label="NRPS-te1"
                     /locus_tag="puwA"
                     /protein_end="2665"
                     /protein_start="2640"
                     /score="47.4"
                     /tool="antismash"
                     /translation="QPQGPYLLGGHSFGGLVAFEMAQQL"
     aSDomain        complement(883..1089)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_PCP.2"
                     /evalue="4.50E-28"
                     /label="puwA_PCP.2"
                     /locus_tag="puwA"
                     /protein_end="2561"
                     /protein_start="2492"
                     /score="89.3"
                     /tool="antismash"
                     /translation="ELQLTQIWSEVLGVKWVGIRDNFFEIGGHSLLAVRLMAQIQQKLH
                     KQLPLASLFQNPTIEELANLLRQS"
     CDS_motif       complement(1264..1302)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0024"
                     /evalue="3.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="puwA"
                     /protein_end="2434"
                     /protein_start="2421"
                     /score="-1.7"
                     /tool="antismash"
                     /translation="AYVVFNSEQQATP"
     CDS_motif       complement(1384..1449)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0023"
                     /evalue="1.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="puwA"
                     /protein_end="2394"
                     /protein_start="2372"
                     /score="36.3"
                     /tool="antismash"
                     /translation="YLGRLDNQVKVRGFRIELGEVE"
     aSDomain        complement(1414..2601)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_AMP-binding.2"
                     /evalue="8.00E-112"
                     /label="puwA_AMP-binding.2"
                     /locus_tag="puwA"
                     /protein_end="2384"
                     /protein_start="1988"
                     /score="365.7"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="ATQVQLTPDHIAVVFGEKQLTYAELDTRANQLAHYLQTLGVQPEV
                     AVGICIERSLDLVVGLLAILKAGGAYVPLDSTYPGDRLAYMLQDSQAAVLLTTSNLVEI
                     FPTHTAQVVCLDAVSWDNLPSHIPVSGLTSDNLAYVIYTSGSTGKPKGVAMPHSALVNL
                     LQWQINHTSIAANAKTLQFAPVSFDVSCQEIFATWCAGGTLVLLPEDTRKDTIALFNLL
                     SEEGVERLFLPFVALQQLAEVSANVESLPPLREIITAGEQLQVTPALKNFLQRLGNCTL
                     HNQYGPSETHVVTAFTLSDDVEEWPMLPPIGQAIANTQTYILDKYLQPVPMGVRGELYI
                     GGVGVARGYLNRPELTAEKFITHNQAKLYKTGDLARFLPDGNIEYLGRLDNQVKVR"
     CDS_motif       complement(1522..1611)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0022"
                     /evalue="2.60E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="puwA"
                     /protein_end="2348"
                     /protein_start="2318"
                     /score="58.0"
                     /tool="antismash"
                     /translation="PMGVRGELYIGGVGVARGYLNRPELTAEKF"
     CDS_motif       complement(1720..1752)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0021"
                     /evalue="2.70E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="puwA"
                     /protein_end="2282"
                     /protein_start="2271"
                     /score="4.7"
                     /tool="antismash"
                     /translation="QYGPSETHVVT"
     CDS_motif       complement(2131..2190)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0020"
                     /evalue="4.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwA"
                     /protein_end="2145"
                     /protein_start="2125"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVAMPH"
     CDS_motif       complement(2377..2418)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0019"
                     /evalue="5.70E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="puwA"
                     /protein_end="2063"
                     /protein_start="2049"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LAILKAGGAYVPLD"
     CDS_motif       complement(2929..3048)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0018"
                     /evalue="1.10E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwA"
                     /protein_end="1879"
                     /protein_start="1839"
                     /score="79.0"
                     /tool="antismash"
                     /translation="KQVALDGYAHQDVPFEQIVEALQPERKLSHAPLFQVMFIL"
     aSDomain        complement(3088..3990)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.50E-123"
                     /label="puwA_Condensation_LCL.2"
                     /locus_tag="puwA"
                     /protein_end="1826"
                     /protein_start="1525"
                     /score="402.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVADG"
                     /tool="antismash"
                     /translation="EPLPMSWAQQRLWFLYQLEGASSTYNMPNVLQITGELQVNALKQT
                     LSDIVQRHEILRTSFHLIDGNPVQVINTDASLSLEIIDLRELSNNQQQAAVEKFSNEEA
                     QKPFDLNQAPLVRATLLQLDANSHVLLFTLHHIVADGWSMGVIIQELSAMYPALAAGKL
                     SPLPDLSIQYADFAVWQRQWLTGEVLETKLNYWQQQLADAPPVLELPTDKPRPAVQTFR
                     GDRLAFQLRKDFSEQLNLLSQQAGATLFMTLQAAFVTLLHRYTGQDDILVGTPIANRNR
                     KELEPLIGFFVNTLVLRNKV"
     CDS_motif       complement(3097..3186)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0017"
                     /evalue="5.00E-18"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwA"
                     /protein_end="1823"
                     /protein_start="1793"
                     /score="57.4"
                     /tool="antismash"
                     /translation="DILVGTPIANRNRKELEPLIGFFVNTLVLR"
     CDS_motif       complement(3439..3477)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0016"
                     /evalue="3.50E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="puwA"
                     /protein_end="1709"
                     /protein_start="1696"
                     /score="19.4"
                     /tool="antismash"
                     /translation="QYADFAVWQRQWL"
     CDS_motif       complement(3526..3591)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0015"
                     /evalue="6.80E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwA"
                     /protein_end="1680"
                     /protein_start="1658"
                     /score="37.8"
                     /tool="antismash"
                     /translation="LHHIVADGWSMGVIIQELSAMY"
     CDS_motif       complement(3808..3921)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0014"
                     /evalue="1.70E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwA"
                     /protein_end="1586"
                     /protein_start="1548"
                     /score="49.3"
                     /tool="antismash"
                     /translation="TYNMPNVLQITGELQVNALKQTLSDIVQRHEILRTSFH"
     CDS_motif       complement(3946..3975)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0013"
                     /evalue="8.20E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="puwA"
                     /protein_end="1540"
                     /protein_start="1530"
                     /score="6.2"
                     /tool="antismash"
                     /translation="SWAQQRLWFL"
     aSDomain        complement(4051..4254)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_PCP.1"
                     /evalue="3.10E-25"
                     /label="puwA_PCP.1"
                     /locus_tag="puwA"
                     /protein_end="1505"
                     /protein_start="1437"
                     /score="80.2"
                     /tool="antismash"
                     /translation="EEIIAAIIAEVLGLEEIGVYDNFFELGGHSLLATQVISRLQEAFP
                     VELPLRCLFEAPSVVELDQFISN"
     aSModule        complement(4051..8421)
                     /complete
                     /domains="nrpspksdomains_puwA_Condensation_LCL.1"
                     /domains="nrpspksdomains_puwA_AMP-binding.1"
                     /domains="nrpspksdomains_puwA_nMT.1"
                     /domains="nrpspksdomains_puwA_PCP.1"
                     /locus_tags="puwA"
                     /monomer_pairings="Asn -> NMe-Asn"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(4876..5535)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="1.60E-124"
                     /label="puwA_nMT.1"
                     /locus_tag="puwA"
                     /protein_end="1230"
                     /protein_start="1010"
                     /score="407.5"
                     /tool="antismash"
                     /translation="GLLIPKAEMREWVESTVDRILDWQPKQVLEIGCGTGMLLFRIAPQ
                     CDCYYGTDISPQALRYVQQQITQMGRDWSQVKLAQRSAENFHGVEQGGFDAVVLNSVVQ
                     YFPSIDYLMQVLENAMQAIASAGFIFIGDVRSLPLLEAFHASVQLAQSLPSLSTGDLQQ
                     RIQRNLNQDSELVIDPAFFTALQQRFPQISHVQIQIKRGEYHNELTQFRYDVTLHLG"
     CDS_motif       complement(5791..5856)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0012"
                     /evalue="8.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwA"
                     /protein_end="925"
                     /protein_start="903"
                     /score="37.1"
                     /tool="antismash"
                     /translation="YLGRTDHQVKLRGFRIELGEIE"
     aSDomain        complement(5821..7023)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_AMP-binding.1"
                     /evalue="6.00E-111"
                     /label="puwA_AMP-binding.1"
                     /locus_tag="puwA"
                     /protein_end="915"
                     /protein_start="514"
                     /score="362.9"
                     /specificity="substrate consensus: Asn"
                     /tool="antismash"
                     /translation="FEAQVELTPDAVAVLGNGEELTYGELNARANQVAHYLQSLGVEAE
                     VLVGICAERSLEMVVGLLGILKAGGAFVPLDPAYPRDRLQYLLEDSQVPVLLTQSHLLN
                     ILPEHQQVICLDTDWQAISQQSQANPVSQVKSTNLAYIIYTSGSTGKPKGTMIIHRGVV
                     NYLSWCIEAYAVADGYGAPVQSSFAFDATITSLFSPLMVGRQVVLLPEKQEIEALCSVL
                     QSKSQFSLVKLTPAHLELLNQIIPPAEAAGQTNAFVIGGEALLGKTLQFWRENAPQTRL
                     INEYGPTETVVGCCIYEVTDDTSLTEGILIGRPIANTQLYILDEYLQPVPIGVRGELYI
                     GGAGVARGYLNRPELTKEKFISHPFIHEPGARLYKTGDLARYQPDGNIEYLGRTDHQVK
                     LR"
     CDS_motif       complement(5944..6033)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0011"
                     /evalue="3.10E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="puwA"
                     /protein_end="874"
                     /protein_start="844"
                     /score="57.8"
                     /tool="antismash"
                     /translation="PIGVRGELYIGGAGVARGYLNRPELTKEKF"
     CDS_motif       complement(6148..6174)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0010"
                     /evalue="5.30E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="puwA"
                     /protein_end="806"
                     /protein_start="797"
                     /score="3.9"
                     /tool="antismash"
                     /translation="EYGPTETVV"
     CDS_motif       complement(6514..6558)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0009"
                     /evalue="1.80E+01"
                     /label="NRPS-E2"
                     /locus_tag="puwA"
                     /protein_end="684"
                     /protein_start="669"
                     /score="-1.4"
                     /tool="antismash"
                     /translation="MIIHRGVVNYLSWCI"
     CDS_motif       complement(6547..6606)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0008"
                     /evalue="3.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="puwA"
                     /protein_end="673"
                     /protein_start="653"
                     /score="28.9"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGTMIIH"
     CDS_motif       complement(6796..6837)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0007"
                     /evalue="3.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwA"
                     /protein_end="590"
                     /protein_start="576"
                     /score="17.1"
                     /tool="antismash"
                     /translation="LGILKAGGAFVPLD"
     CDS_motif       complement(7360..7479)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0006"
                     /evalue="2.10E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwA"
                     /protein_end="402"
                     /protein_start="362"
                     /score="78.0"
                     /tool="antismash"
                     /translation="QQVALEAYEHQDVPFEQVVEALQPERNLDHNPLFQVMLVL"
     aSDomain        complement(7519..8421)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.70E-123"
                     /label="puwA_Condensation_LCL.1"
                     /locus_tag="puwA"
                     /protein_end="349"
                     /protein_start="48"
                     /score="403.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVVDG"
                     /tool="antismash"
                     /translation="QAIPLSFAQQRLWFLDQLVGLSATYNTPTALQITGKLNINALEQA
                     IIEIVRRHEVLRTTFQEINNTPRQVVHPTVMVNLPVVDLQDLSDIEKASQVQQLVHQEA
                     HKPFNLQQPPLIRGQILRLDETSHVLLLTVHHIVVDGWSMGIFIQELSALYPAFATAKP
                     SPLAELPIQYADFAVWQRQWLSGEVLETKLNYWRQKLAGAPPLLELPTDRPRPPIETFR
                     GGSYTFTLSSQLTQQILSLSQKSGVTLFMTLQAAFVTLLHRYTSQDDILVGTPIANRNR
                     QDIESLIGFFVNTLVLRTKL"
     CDS_motif       complement(7528..7617)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0005"
                     /evalue="1.60E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwA"
                     /protein_end="346"
                     /protein_start="316"
                     /score="55.8"
                     /tool="antismash"
                     /translation="DILVGTPIANRNRQDIESLIGFFVNTLVLR"
     CDS_motif       complement(7870..7908)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0004"
                     /evalue="3.50E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="puwA"
                     /protein_end="232"
                     /protein_start="219"
                     /score="19.4"
                     /tool="antismash"
                     /translation="QYADFAVWQRQWL"
     CDS_motif       complement(7957..8022)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0003"
                     /evalue="1.20E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwA"
                     /protein_end="203"
                     /protein_start="181"
                     /score="40.2"
                     /tool="antismash"
                     /translation="VHHIVVDGWSMGIFIQELSALY"
     CDS_motif       complement(8242..8355)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0002"
                     /evalue="1.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwA"
                     /protein_end="108"
                     /protein_start="70"
                     /score="59.3"
                     /tool="antismash"
                     /translation="ATYNTPTALQITGKLNINALEQAIIEIVRRHEVLRTTF"
     CDS_motif       complement(8374..8406)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0001"
                     /evalue="5.70E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="puwA"
                     /protein_end="64"
                     /protein_start="53"
                     /score="9.4"
                     /tool="antismash"
                     /translation="SFAQQRLWFLD"
     gene            complement(8971..10902)
                     /gene="orf2"
     CDS             complement(8971..10902)
                     /codon_start=1
                     /gene="orf2"
                     /note="patatin-like phospholipase"
                     /product="ORF2"
                     /protein_id="AXN93606.1"
                     /transl_table=11
                     /translation="MVKDNEQNQSEAAVALQPNQFTPSGLVFDGKDIYIDLGKKAEFKI
                     AQQITLEAWINCQAQRRRTGIITNVFDTGQIESGYGLLLDGKSGIFFALKTPSKGIQYL
                     SSKENSIQLNHWHHIAGTYDGKRMRVYVDGVEKATKATADSNIDYNPENDLVIGIYQDN
                     NESYPFQGKIAEVRIWNKARSEAEIQADMTHILVGNEPGLVGYWPLSDAPGTIIIQDKT
                     NHANHGNIIDKTVGVKTEISRENQQPTPPQSESQEVIPKTTQPPTSMLEQTQVIIPETP
                     KATKTKQESTKNKTSKYPYKILSIDGGGIRGIIPAMILEEIETRTQKPIASLFDLIAGT
                     STGGIIALGLTKPQLNATKKPSYTAKDLVNIFAEHGNVIFYEPLYAELLGEFDEILKPK
                     YTSEGRNDILTQYFGSTTIVEAITEILIPSYDIEQRVPVLFSSNLNKENNTSRKLRKIG
                     EGFTMKEAAMATSAAPTYFAPYRIPTSHNENGFYTLVDGGVFANNPTGLAVIESIIGAK
                     EAIKKGEEPWTLDNTLVVSLGTGSLTKPYPYQEAKNWGLLGWARPMLNIVLDGVNQAIS
                     SQIEELIPQSEDKSQQQYYRLQAYLDESLEAMDNAKFNNIRMLIQVAKQMIAERTEEID
                     ELCNKLVN"
     gene            12352..14442
                     /gene="orf3"
     CDS             12352..14442
                     /codon_start=1
                     /gene="orf3"
                     /note="dynamin family protein"
                     /product="ORF3"
                     /protein_id="AXN93607.1"
                     /transl_table=11
                     /translation="MDHTIQAESFIDNLDKVAGVRQEISVCLAQMGDILSQAELAGKKT
                     SGALGLSSDIENINLASQNLHQGIFRLLVLGDMKRGKSTFINALIGENILPNAVNPCTA
                     LLTILRYGEEKKVTVHFNDQKTPEQLEFKEFKQKYTIDPKEAKQLGKGKKMVFAEVSHA
                     IVEYPLPLLSKGLEIIDSPGLNDTEDRNETSLGYINNCHAILFLMRASQPYTLAERRYL
                     ENYIKGRGLTVFFIINGWDQIQEGILDPDDEEELQTAEMQLRELFEVNLAQYCQINGKD
                     IYSERVFEISAINALRRRIKNQSASLEGTGFPELLRSLNTFLTQDRAIAQLQPAIILAH
                     QTYTNIQAAIQRRLSLLKQDVSEMKQRISSVEPEFEQLGIIRDQFQQEIITTRDIQAKT
                     IAESLRSYILNLGNTFETDFLPYQPDLELFDFLNKDKREAFNELLQQAFEQYTADKIAT
                     WTLTVEQDMNAAFAKLSTSAATYGASYSQVTDQIANKLSGQELKRKPQNTTAEDSPTWT
                     KWAMGLLSLSRGNIAGVAMAQAGFDWKNILLNYIAAIGVNSVTSSITGIFLGPVGLAFL
                     GMGIGFVQADQARQKLVQTTQKELTKYLPQAAEEYLPQIRTGVEECFNTYEREVIEQIN
                     KDITQRRAELDNLLQQKAAHEINLQTESQRLQSVAAEVYQQLQQVDKVYSVVNTETAKS
                     AD"
     gene            14989..17133
                     /gene="puwI"
     CDS             14989..17133
                     /NRPS_PKS="Domain: CAL_domain (42-494). E-value: 2.1e-132.
                     Score: 434.1. Matches aSDomain:
                     nrpspksdomains_puwI_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (628-698). E-value: 5.3e-19. Score:
                     60.3. Matches aSDomain: nrpspksdomains_puwI_ACP.1"
                     /codon_start=1
                     /gene="puwI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /note="fatty acyl-AMP ligase; FAAL"
                     /product="PuwI"
                     /protein_id="AXN93608.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 6.6e-262, bitscore:
                     862.0, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-93, bitscore:
                     302.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.3e-16, bitscore:
                     48.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSIILQETTTLVDLLQLRALQHPHKAAFTFLQDGETAAYSLTYQ
                     ALEQKARSIAAKLQTLVTRGDNASPAIGVRALLLYPPGLEFISAFFGCLYAQVVAVPAY
                     PPRRNQNLARLQAIVADTQATVVLTTTALLSNREAWLNQAPELAQVQWLATDDIDVNLA
                     ADWQQPRISSDTLAFLQYTSGSTGKPKGVMVSHENVLYNQRMIQLAYQHTQETIFVGWL
                     PLFHDMGLIGNVLQPLYLGISCYLMSPVAFLQKPIRWLQAISRYQATTSGGPNFAYDLC
                     VSKITPEQIASLDLSSWELAFNGAEPVQAETLEKFAAKFKSCGFRAEAFYPCYGMAETT
                     LFVSGGMKTSAPVVLSVDEAAIEENRVVVTSGEQPQGKQIVSCGQTWLEQKIAIANPET
                     LTQCSPEEVGEIWVSGANVAAGYWQNSEATKETFQAYLADTGEGEFLRTGDLGFIRDGE
                     LFVTGRIKDLIIIRGQNHYPQDIELTTQKSHSALRLGCGAAFSITVAGEERLVITQEVE
                     RSYLRQLDVDEVVGAIRQAVSQQHELQVYAVVLLKTASIPKTSSGKIQRQACRTGFLAR
                     NLDIVGEWQVNFQELELAALQTSLATLLEHVQQGAQNHSASEQTALNSEKIQNWLVTHL
                     ALSLKLPPDEIDTQESFAHYGLDSSVAVSMTSELGEWLGWELDPTLFWEFPSIAALAQH
                     LDAECRLLKSTNQVKLSGKI"
     aSDomain        15115..16470
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwI_CAL_domain.1"
                     /evalue="2.10E-132"
                     /label="puwI_CAL_domain.1"
                     /locus_tag="puwI"
                     /protein_end="494"
                     /protein_start="42"
                     /score="434.1"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYQALEQKARSIAAKLQTLVTRGDNASPAIGVRALLLYPPGLEFI
                     SAFFGCLYAQVVAVPAYPPRRNQNLARLQAIVADTQATVVLTTTALLSNREAWLNQAPE
                     LAQVQWLATDDIDVNLAADWQQPRISSDTLAFLQYTSGSTGKPKGVMVSHENVLYNQRM
                     IQLAYQHTQETIFVGWLPLFHDMGLIGNVLQPLYLGISCYLMSPVAFLQKPIRWLQAIS
                     RYQATTSGGPNFAYDLCVSKITPEQIASLDLSSWELAFNGAEPVQAETLEKFAAKFKSC
                     GFRAEAFYPCYGMAETTLFVSGGMKTSAPVVLSVDEAAIEENRVVVTSGEQPQGKQIVS
                     CGQTWLEQKIAIANPETLTQCSPEEVGEIWVSGANVAAGYWQNSEATKETFQAYLADTG
                     EGEFLRTGDLGFIRDGELFVTGRIKDLIIIRGQNHYPQDIELTTQKSHSALRL"
     aSModule        15115..17082
                     /complete
                     /domains="nrpspksdomains_puwI_CAL_domain.1"
                     /domains="nrpspksdomains_puwI_ACP.1"
                     /locus_tags="puwI"
                     /monomer_pairings="NH2 -> NH2"
                     /starter_module
                     /tool="antismash"
                     /type="cal"
     CDS_motif       15517..15576
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwI_0001"
                     /evalue="5.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwI"
                     /protein_end="196"
                     /protein_start="176"
                     /score="31.1"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGKPKGVMVSH"
     CDS_motif       16009..16053
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwI_0002"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="puwI"
                     /protein_end="355"
                     /protein_start="340"
                     /score="-3.2"
                     /tool="antismash"
                     /translation="LFVSGGMKTSAPVVL"
     CDS_motif       16207..16287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwI_0003"
                     /evalue="3.90E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="puwI"
                     /protein_end="433"
                     /protein_start="406"
                     /score="32.0"
                     /tool="antismash"
                     /translation="EVGEIWVSGANVAAGYWQNSEATKETF"
     CDS_motif       16372..16434
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwI_0004"
                     /evalue="5.40E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="puwI"
                     /protein_end="482"
                     /protein_start="461"
                     /score="19.0"
                     /tool="antismash"
                     /translation="TGRIKDLIIIRGQNHYPQDIE"
     aSDomain        16873..17082
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwI_ACP.1"
                     /evalue="5.30E-19"
                     /label="puwI_ACP.1"
                     /locus_tag="puwI"
                     /protein_end="698"
                     /protein_start="628"
                     /score="60.3"
                     /tool="antismash"
                     /translation="NWLVTHLALSLKLPPDEIDTQESFAHYGLDSSVAVSMTSELGEWL
                     GWELDPTLFWEFPSIAALAQHLDAE"
     gene            17136..18419
                     /gene="puwJ"
     CDS             17136..18419
                     /codon_start=1
                     /gene="puwJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome-like protein"
                     /product="PuwJ"
                     /protein_id="AXN93609.1"
                     /sec_met_domain="p450 (E-value: 1e-36, bitscore: 116.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESIAESSQEMINSGQNQPARTVKPFRFNPLLANLHQDPYPTYHH
                     LREKDPVHQNLLNAWVLTRYEDVRTVLRDPRFCVDKLATRVRNKSNYLTQQKDLDTLAD
                     VTGKWLIYLDPPDHTRLRKLVGKAFSPSVIDPLRPYIQGIVDQLLDKVQHQGNMEVIAD
                     LAAPLPVKVIAKMLGVPDQDCPQLHQWSNDLSRILDPLLPLQTYEHLNQIVLEFAEYFR
                     AIFAERRKSPQEDLISALIEARDQGDKLSEVEMLSTCILLFIAGEETTVNTIGNGILAL
                     LRHPEQLEKLRQEPTIIQSAVEEILRYDSPVQYAQRIATEDVEIGGKLIKVGDKVVACL
                     GAANRDPAQFIDPDRLDLTRSDNRHMAFIDGTHTCLGGALARLNSQIAINTFAQRFSHI
                     ELQTDQLDWRKNIALRGLKSLSVSFKSN"
     gene            18459..26108
                     /gene="puwB"
     CDS             18459..26108
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (5-425). E-value:
                     8.4e-188. Score: 616.5. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (550-847). E-value: 6.7e-108.
                     Score: 352.5. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (943-1156). E-value: 2.5e-35.
                     Score: 113.9. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_DH2.1"
                     /NRPS_PKS="Domain: cMT (1388-1600). E-value: 8.9e-103.
                     Score: 335.8. Matches aSDomain: nrpspksdomains_puwB_cMT.1"
                     /NRPS_PKS="Domain: PKS_ER (1840-2147). E-value: 1.3e-125.
                     Score: 410.6. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2158-2335). E-value: 8.1e-71.
                     Score: 229.7. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (2431-2500). E-value: 3.1e-26.
                     Score: 83.5. Matches aSDomain: nrpspksdomains_puwB_ACP.1"
                     /codon_start=1
                     /gene="puwB"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /note="hybrid PKS/NRPS; aminotransferase; oxygenase"
                     /product="PuwB"
                     /protein_id="AXN93610.1"
                     /sec_met_domain="mod_KS (E-value: 5.5e-185, bitscore:
                     604.9, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 3e-197, bitscore: 645.3,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 2.2e-178, bitscore:
                     583.1, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.9e-98, bitscore:
                     318.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 6.7e-166, bitscore:
                     542.0, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.8e-188, bitscore:
                     616.5, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 8e-72, bitscore: 231.9,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.5e-108, bitscore:
                     352.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 3.8e-09, bitscore: 26.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.6e-21, bitscore:
                     64.8, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.7e-64, bitscore:
                     206.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-15, bitscore:
                     47.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKEPIAIIGIGCRFPGAKNPEAFWHLLRDGIDAITEVPKTRWDI
                     DDFYDADPATPDKMTTRWGGFLEQIDQFDPQFFNIAPREAASVDPQHRLLLETTWEALE
                     DAGQNPTALAGKPAGVFMGISSFDYDKLRFQNPVNLDSYAGTGTALSLAANRISYALNF
                     TGPSIAIDTACSSSLVAVHLACQSLRNGESTLALAGGVNVMASPWVTVTFSKGGFMATD
                     GRCKAFDSRANGYVRSEGAGVVVLKLLSQAEADGDRIYAIIRGSAVNQDGRSNGITAPN
                     SLAQEAVLREAYRQAGVSPGKVQYIEAHGTGTKLGDPIEVKALGKVLNEGRIPGEYCAL
                     GSVKTNIGHAEAAAGIAGLIKVALSLKHGQIPASLHFQEANPYIPFDKLPLRVQQKLES
                     WPEIGETTIAGVSSFGFGGTNAHVVLGRQGAGSRGQGAGSRRQKDVFSPTPLHPYTPIP
                     LHLLTLSAKSEKALQELVQSYQDYLKNHPQVSLTDVCFTANVGRNHFDYRLGIASNSTI
                     KLQEQLAAFLLKQDTPGVFQGQINSRKHPKVVFLFTGQGSQYVDMGRKLYETHPTFRQI
                     LDDCNQILLPYLETPLLEILYPQLPVLSPQSPINETAYTQPALFALEYALAKLWQSWGI
                     EASAVMGHSVGEYVAACLAGVFSLEDGLKLIAERGRLMQALPSNGTMAAIMADEQTVLS
                     AIQPYGEQIAIAAYNGAESLVISGQRQAIEAVCQQLTNQGIQTKPLQVSHPFHSPLMEA
                     MLGDFEQVAKTVQYSSPKIPLISNLTGQIATTDIATPEYWVHHIRQPVQFASSMKLLHQ
                     QGYQIFVEIGAKPTLIGMGRQCLPDGVGVWLPSLHPKQGEWEQILASLAALYVRGVPIN
                     WGEFYRHSDCEPVSLPTYPFQRQRYWIETVSPLHQPSFNLVQGQQHPLLGQRLNLAGVK
                     EICFQSEISQNQPAYLPDHRVFGEVIVPATAYLEMALAAGFKIYKSVQLVLEDISILQP
                     LILGEIGITLQISLSPGDGSYPFRIFSSENITDTESVWRLHATGKLLRGENQAEPIQTD
                     LTKLRSPCYENIAPLNYYQQCQNRGIDYGSSFQAIQQLWYAPGLAMGQVQLAETWADQN
                     YHLHPIILDASFQVLGAALLHENQLDTYLPVEIKRLQIHSSPGNLVWSHAEINPDTNQE
                     LISGNVSLYTEDGVKIVHVQGLELKRSRLLPTTQDNWHNWLYQVAWRQKVHFASSQLSP
                     DYLVSPEQVSMKISAKLPDILTDFNWSEYQQVFTQMEALSIAYIIHAFAQMGRKFQLGQ
                     RFATADIITQLGIVNRHHRLLHRLLEIVADAGYLQESNSQWQVIHIPQDSNPDTKLNLL
                     LAKYPSAVAELTLLGRCASKLASVLQGDSDPLQLLFPEGDMTTATQVYQDSPGSQVLNS
                     LVQQAISSALAQLPQDRGVRILEIGAGTGGTTAYILPTLPAKQTEYIFTDLSPRFTTQA
                     QEKFRDYPFVQYQVLDIEQELKPQGFEFHQYDVVVAANVLHATQDLAQTLQNIRQLLAP
                     QGLLILLEGTIPQAWLDLTFGLTEGWWRFSDTELRPNYPLLTSEQWQQVLLQEGYQAAV
                     TLPLAAATQGSLNQQSVIVAQAAPTQKTVAAATSKHWLVLADSQGLGEKLATQLREKGD
                     ICTLVFSGEDYKLLDRETLTLNPTQPEHFQQLLTRISNSETALHGVINCWSLDTSDALT
                     SLNLKLTSKDLKAASRQSCGSTLHLLQALTKTDFTSQPRLWLVTRGAQSVEGNVSGVTQ
                     SALWGMGKVIALEHPELKCVRVDLDSHPVEDEVNALLAEILASDEEDQVAFRHQQRYVA
                     RLIRTGENQLEIPENQPFTLTISQKGTLENLTFEPTVRRSPDAGEVEIRVRATGLNFRD
                     LLNALDLYPGDAGTLGGECAGEIVAVGAGVSGLAVGDAVVAIAPASFSQYVTVNAQMVA
                     PKPANLTFAEAATIPITFLTAYYSLHHLGKIAPGERVLIHAAAGGVGQAAIQLAQQIGA
                     EVFATASPGKWDFLKSLGVEQIMNSRSLDFAEQIKEITEKQGVNIVLNSLTSDEFISKS
                     LSVLQPQGRFVEIAKRGVLQTDEVLKVRSDIAYFLVDLVEVCQQQPTLIQSMLAKLMPQ
                     FATGQLKPLPQTQFPITDVVDAFRYMQQAKHIGKIVVTQTELTFRADSTYLITGGMGGL
                     GLLVAEWMVEKGARHLVLLGRSGANGEVKQSIKTLQQKGAQVMVTQADVVNLEQMTKVI
                     EDIERSLPPLRGIIHAVGVLDDGVLQQQTWERFTKVMSPKVEGAWNLHQLTQHLPLDFF
                     VLFSSVASLFGSPGQANHAAANAFLDTFAHYRQQQGLPGLSINWGVVTDIGAAAKRQAD
                     SWVKAKGIGTIAPHQVLAVLEQQMLAPASPQVGVVPVDWSKFNISPFFQDLQPQAKSTE
                     PSSQAGEFLQQLDTIPKGEHRAYLMNHVCSQVATVLGGNPATAIDIQQGFFDLGMDSLT
                     SVELRNRLQTSLGCSLPSTLTFKYPTVTALVDYLAMEVLNLATPPPETNVKNQDWEAVK
                     QLSDDEVDASIAKEIAELEALLRGKS"
     aSDomain        18474..19733
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="8.40E-188"
                     /label="puwB_PKS_KS.1"
                     /locus_tag="puwB"
                     /protein_end="425"
                     /protein_start="5"
                     /score="616.5"
                     /tool="antismash"
                     /translation="IAIIGIGCRFPGAKNPEAFWHLLRDGIDAITEVPKTRWDIDDFYD
                     ADPATPDKMTTRWGGFLEQIDQFDPQFFNIAPREAASVDPQHRLLLETTWEALEDAGQN
                     PTALAGKPAGVFMGISSFDYDKLRFQNPVNLDSYAGTGTALSLAANRISYALNFTGPSI
                     AIDTACSSSLVAVHLACQSLRNGESTLALAGGVNVMASPWVTVTFSKGGFMATDGRCKA
                     FDSRANGYVRSEGAGVVVLKLLSQAEADGDRIYAIIRGSAVNQDGRSNGITAPNSLAQE
                     AVLREAYRQAGVSPGKVQYIEAHGTGTKLGDPIEVKALGKVLNEGRIPGEYCALGSVKT
                     NIGHAEAAAGIAGLIKVALSLKHGQIPASLHFQEANPYIPFDKLPLRVQQKLESWPEIG
                     ETTIAGVSSFGFGGTNAHVVL"
     aSModule        18474..25958
                     /complete
                     /domains="nrpspksdomains_puwB_PKS_KS.1"
                     /domains="nrpspksdomains_puwB_PKS_AT.1"
                     /domains="nrpspksdomains_puwB_PKS_DH2.1"
                     /domains="nrpspksdomains_puwB_cMT.1"
                     /domains="nrpspksdomains_puwB_PKS_ER.1"
                     /domains="nrpspksdomains_puwB_PKS_KR.1"
                     /domains="nrpspksdomains_puwB_ACP.1"
                     /locus_tags="puwB"
                     /monomer_pairings="mal -> Me-redmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       18951..18998
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0001"
                     /evalue="1.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="puwB"
                     /protein_end="180"
                     /protein_start="164"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GPSIAIDTACSSSLVA"
     CDS_motif       19140..19178
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0002"
                     /evalue="5.20E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="puwB"
                     /protein_end="240"
                     /protein_start="227"
                     /score="13.1"
                     /tool="antismash"
                     /translation="FDSRANGYVRSEG"
     CDS_motif       19371..19418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0003"
                     /evalue="1.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="puwB"
                     /protein_end="320"
                     /protein_start="304"
                     /score="13.7"
                     /tool="antismash"
                     /translation="YIEAHGTGTKLGDPIE"
     CDS_motif       19479..19523
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0004"
                     /evalue="8.90E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="puwB"
                     /protein_end="355"
                     /protein_start="340"
                     /score="11.7"
                     /tool="antismash"
                     /translation="GSVKTNIGHAEAAAG"
     aSDomain        20109..20999
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_AT.1"
                     /evalue="6.70E-108"
                     /label="puwB_PKS_AT.1"
                     /locus_tag="puwB"
                     /protein_end="847"
                     /protein_start="550"
                     /score="352.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYVDMGRKLYETHPTFRQILDDCNQILLPYLETPLLEI
                     LYPQLPVLSPQSPINETAYTQPALFALEYALAKLWQSWGIEASAVMGHSVGEYVAACLA
                     GVFSLEDGLKLIAERGRLMQALPSNGTMAAIMADEQTVLSAIQPYGEQIAIAAYNGAES
                     LVISGQRQAIEAVCQQLTNQGIQTKPLQVSHPFHSPLMEAMLGDFEQVAKTVQYSSPKI
                     PLISNLTGQIATTDIATPEYWVHHIRQPVQFASSMKLLHQQGYQIFVEIGAKPTLIGMG
                     RQCLPDGVGVWLPSLH"
     CDS_motif       20112..20159
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0005"
                     /evalue="1.80E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="puwB"
                     /protein_end="567"
                     /protein_start="551"
                     /score="20.3"
                     /tool="antismash"
                     /translation="FTGQGSQYVDMGRKLY"
     CDS_motif       20298..20354
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0006"
                     /evalue="5.50E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="puwB"
                     /protein_end="632"
                     /protein_start="613"
                     /score="16.2"
                     /tool="antismash"
                     /translation="YTQPALFALEYALAKLWQS"
     CDS_motif       20358..20480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0007"
                     /evalue="4.00E-26"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="puwB"
                     /protein_end="674"
                     /protein_start="633"
                     /score="83.4"
                     /tool="antismash"
                     /translation="GIEASAVMGHSVGEYVAACLAGVFSLEDGLKLIAERGRLMQ"
     CDS_motif       20766..20798
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0008"
                     /evalue="4.70E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="puwB"
                     /protein_end="780"
                     /protein_start="769"
                     /score="9.8"
                     /tool="antismash"
                     /translation="PKIPLISNLTG"
     CDS_motif       20832..20867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0009"
                     /evalue="2.30E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="puwB"
                     /protein_end="803"
                     /protein_start="791"
                     /score="14.6"
                     /tool="antismash"
                     /translation="YWVHHIRQPVQF"
     aSDomain        21288..21926
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_DH2.1"
                     /evalue="2.50E-35"
                     /label="puwB_PKS_DH2.1"
                     /locus_tag="puwB"
                     /protein_end="1156"
                     /protein_start="943"
                     /score="113.9"
                     /tool="antismash"
                     /translation="AYLPDHRVFGEVIVPATAYLEMALAAGFKIYKSVQLVLEDISILQ
                     PLILGEIGITLQISLSPGDGSYPFRIFSSENITDTESVWRLHATGKLLRGENQAEPIQT
                     DLTKLRSPCYENIAPLNYYQQCQNRGIDYGSSFQAIQQLWYAPGLAMGQVQLAETWADQ
                     NYHLHPIILDASFQVLGAALLHENQLDTYLPVEIKRLQIHSSPGNLVWSH"
     CDS_motif       21291..21368
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0010"
                     /evalue="3.30E-12"
                     /label="PKSI-DH_m2"
                     /locus_tag="puwB"
                     /protein_end="970"
                     /protein_start="944"
                     /score="38.7"
                     /tool="antismash"
                     /translation="YLPDHRVFGEVIVPATAYLEMALAAG"
     aSDomain        22623..23258
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="8.90E-103"
                     /label="puwB_cMT.1"
                     /locus_tag="puwB"
                     /protein_end="1600"
                     /protein_start="1388"
                     /score="335.8"
                     /tool="antismash"
                     /translation="QVYQDSPGSQVLNSLVQQAISSALAQLPQDRGVRILEIGAGTGGT
                     TAYILPTLPAKQTEYIFTDLSPRFTTQAQEKFRDYPFVQYQVLDIEQELKPQGFEFHQY
                     DVVVAANVLHATQDLAQTLQNIRQLLAPQGLLILLEGTIPQAWLDLTFGLTEGWWRFSD
                     TELRPNYPLLTSEQWQQVLLQEGYQAAVTLPLAAATQGSLNQQSVIVAQ"
     aSDomain        23979..24899
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_ER.1"
                     /evalue="1.30E-125"
                     /label="puwB_PKS_ER.1"
                     /locus_tag="puwB"
                     /protein_end="2147"
                     /protein_start="1840"
                     /score="410.6"
                     /tool="antismash"
                     /translation="GTLENLTFEPTVRRSPDAGEVEIRVRATGLNFRDLLNALDLYPGD
                     AGTLGGECAGEIVAVGAGVSGLAVGDAVVAIAPASFSQYVTVNAQMVAPKPANLTFAEA
                     ATIPITFLTAYYSLHHLGKIAPGERVLIHAAAGGVGQAAIQLAQQIGAEVFATASPGKW
                     DFLKSLGVEQIMNSRSLDFAEQIKEITEKQGVNIVLNSLTSDEFISKSLSVLQPQGRFV
                     EIAKRGVLQTDEVLKVRSDIAYFLVDLVEVCQQQPTLIQSMLAKLMPQFATGQLKPLPQ
                     TQFPITDVVDAFRYMQQAKHIGKIVV"
     CDS_motif       24114..24164
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0011"
                     /evalue="2.00E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="puwB"
                     /protein_end="1902"
                     /protein_start="1885"
                     /score="-2.0"
                     /tool="antismash"
                     /translation="AGTLGGECAGEIVAVGA"
     CDS_motif       24288..24332
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0012"
                     /evalue="1.90E-05"
                     /label="PKSI-ER_m4"
                     /locus_tag="puwB"
                     /protein_end="1958"
                     /protein_start="1943"
                     /score="17.9"
                     /tool="antismash"
                     /translation="AATIPITFLTAYYSL"
     CDS_motif       24357..24419
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0013"
                     /evalue="4.20E-11"
                     /label="PKSI-ER_m5"
                     /locus_tag="puwB"
                     /protein_end="1987"
                     /protein_start="1966"
                     /score="34.9"
                     /tool="antismash"
                     /translation="GERVLIHAAAGGVGQAAIQLA"
     CDS_motif       24429..24476
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0014"
                     /evalue="1.70E-04"
                     /label="PKSI-ER_m6"
                     /locus_tag="puwB"
                     /protein_end="2006"
                     /protein_start="1990"
                     /score="14.4"
                     /tool="antismash"
                     /translation="GAEVFATASPGKWDFL"
     CDS_motif       24852..24899
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0015"
                     /evalue="5.20E-08"
                     /label="PKSI-ER_m9"
                     /locus_tag="puwB"
                     /protein_end="2147"
                     /protein_start="2131"
                     /score="25.4"
                     /tool="antismash"
                     /translation="AFRYMQQAKHIGKIVV"
     CDS_motif       24933..25031
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0016"
                     /evalue="5.00E-19"
                     /label="PKSI-KR_m1"
                     /locus_tag="puwB"
                     /protein_end="2191"
                     /protein_start="2158"
                     /score="60.8"
                     /tool="antismash"
                     /translation="TYLITGGMGGLGLLVAEWMVEKGARHLVLLGRS"
     aSDomain        24933..25463
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_KR.1"
                     /evalue="8.10E-71"
                     /label="puwB_PKS_KR.1"
                     /locus_tag="puwB"
                     /protein_end="2335"
                     /protein_start="2158"
                     /score="229.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TYLITGGMGGLGLLVAEWMVEKGARHLVLLGRSGANGEVKQSIKT
                     LQQKGAQVMVTQADVVNLEQMTKVIEDIERSLPPLRGIIHAVGVLDDGVLQQQTWERFT
                     KVMSPKVEGAWNLHQLTQHLPLDFFVLFSSVASLFGSPGQANHAAANAFLDTFAHYRQQ
                     QGLPGLSINWGVVT"
     CDS_motif       25257..25286
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0017"
                     /evalue="2.60E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="puwB"
                     /protein_end="2276"
                     /protein_start="2266"
                     /score="11.2"
                     /tool="antismash"
                     /translation="PKVEGAWNLH"
     CDS_motif       25308..25418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0018"
                     /evalue="3.20E-22"
                     /label="PKSI-KR_m4"
                     /locus_tag="puwB"
                     /protein_end="2320"
                     /protein_start="2283"
                     /score="71.2"
                     /tool="antismash"
                     /translation="LDFFVLFSSVASLFGSPGQANHAAANAFLDTFAHYRQ"
     aSDomain        25752..25958
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_ACP.1"
                     /evalue="3.10E-26"
                     /label="puwB_ACP.1"
                     /locus_tag="puwB"
                     /protein_end="2500"
                     /protein_start="2431"
                     /score="83.5"
                     /tool="antismash"
                     /translation="HVCSQVATVLGGNPATAIDIQQGFFDLGMDSLTSVELRNRLQTSL
                     GCSLPSTLTFKYPTVTALVDYLAM"
     gene            26420..27898
                     /gene="puwc"
     CDS             26420..27898
                     /NRPS_PKS="Domain: CAL_domain (1-398). E-value: 3.5e-115.
                     Score: 377.1. Matches aSDomain:
                     nrpspksdomains_puwc_CAL_domain.1"
                     /codon_start=1
                     /gene="puwc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /note="fatty acyl-AMP ligase; FAAL"
                     /product="PuwC"
                     /protein_id="AXN93611.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 5.5e-226, bitscore:
                     742.7, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-81, bitscore:
                     263.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVPAYPPRRNQNLSRLQAIVADAQATVILTTKSLLPQLQEWFSQ
                     NAELAAIKLLATDDLNSNLAANWQAPQLSQDSLAFLQYTSGSTGKPKGVMVSHGNLLHN
                     SEYLKQAFGLSSESISVSWLPSFHDMGLIEGILQPLYTGFLGVLMPPVSFVQQPIRWLK
                     AITRYRGTHGGSPNFGYDLCTRKITPAQIQQLDLSSWNNAYCGAEPVSKATLEKFTEIF
                     QACGFRSNAFDPCYGLAEATLMVSGGLVEDEPVYCAVETEALENNQVVISQGEQQNVKQ
                     LVGCGRAWLDTKIAIAHPENLTQCKPDEIGEIWVSGATVACGYWQRPEETKQTFHAYLA
                     DTKQGPFLRTGDLGFLRDGELFVTGRIKDVLIIRGRNHYPQDIELTVEQSHPALRPSCG
                     AAFTVTVKGEEKLIVVQEVERSWLRKLDGEAVIIAIRKAIAQQHELQIYATFLIKTNTI
                     PKTSSGKIQRRLCREKLLTGKLEVLASDNKNLIS"
     aSDomain        26423..27613
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwc_CAL_domain.1"
                     /evalue="3.50E-115"
                     /label="puwc_CAL_domain.1"
                     /locus_tag="puwc"
                     /protein_end="398"
                     /protein_start="1"
                     /score="377.1"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="AVPAYPPRRNQNLSRLQAIVADAQATVILTTKSLLPQLQEWFSQN
                     AELAAIKLLATDDLNSNLAANWQAPQLSQDSLAFLQYTSGSTGKPKGVMVSHGNLLHNS
                     EYLKQAFGLSSESISVSWLPSFHDMGLIEGILQPLYTGFLGVLMPPVSFVQQPIRWLKA
                     ITRYRGTHGGSPNFGYDLCTRKITPAQIQQLDLSSWNNAYCGAEPVSKATLEKFTEIFQ
                     ACGFRSNAFDPCYGLAEATLMVSGGLVEDEPVYCAVETEALENNQVVISQGEQQNVKQL
                     VGCGRAWLDTKIAIAHPENLTQCKPDEIGEIWVSGATVACGYWQRPEETKQTFHAYLAD
                     TKQGPFLRTGDLGFLRDGELFVTGRIKDVLIIRGRNHYPQDIELTVEQSHPALRPSC"
     CDS_motif       26654..26713
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwc_0001"
                     /evalue="3.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwc"
                     /protein_end="98"
                     /protein_start="78"
                     /score="31.7"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGKPKGVMVSH"
     CDS_motif       27344..27424
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwc_0002"
                     /evalue="1.40E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="puwc"
                     /protein_end="335"
                     /protein_start="308"
                     /score="36.6"
                     /tool="antismash"
                     /translation="EIGEIWVSGATVACGYWQRPEETKQTF"
     CDS_motif       27509..27571
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwc_0003"
                     /evalue="2.40E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="puwc"
                     /protein_end="384"
                     /protein_start="363"
                     /score="17.0"
                     /tool="antismash"
                     /translation="TGRIKDVLIIRGRNHYPQDIE"
     CDS_motif       27626..27667
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwc_0004"
                     /evalue="6.20E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="puwc"
                     /protein_end="416"
                     /protein_start="402"
                     /score="-2.3"
                     /tool="antismash"
                     /translation="TVTVKGEEKLIVVQ"
     gene            27975..28256
                     /gene="puwD"
     CDS             27975..28256
                     /NRPS_PKS="Domain: ACP (16-86). E-value: 1.1e-17. Score:
                     56.1. Matches aSDomain: nrpspksdomains_puwD_ACP.1"
                     /codon_start=1
                     /gene="puwD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /note="acyl-carrier protein; ACP"
                     /product="PuwD"
                     /protein_id="AXN93612.1"
                     /sec_met_domain="PP-binding (E-value: 1.2e-15, bitscore:
                     47.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTANTKTIPSTEQIQDWLISYMADMLEITTNEVDIRMLFDEYGL
                     DSSMTIGMIGDLETWLGCNLDPTLVYDYSTIEDLAKHLGSNLISDNLL"
     aSDomain        28023..28232
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwD_ACP.1"
                     /evalue="1.10E-17"
                     /label="puwD_ACP.1"
                     /locus_tag="puwD"
                     /protein_end="86"
                     /protein_start="16"
                     /score="56.1"
                     /tool="antismash"
                     /translation="DWLISYMADMLEITTNEVDIRMLFDEYGLDSSMTIGMIGDLETWL
                     GCNLDPTLVYDYSTIEDLAKHLGSN"
     gene            28358..37657
                     /gene="puwE"
     CDS             28358..37657
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (36-461). E-value:
                     3.3e-187. Score: 614.5. Matches aSDomain:
                     nrpspksdomains_puwE_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (572-866). E-value: 6.4e-113.
                     Score: 369.0. Matches aSDomain:
                     nrpspksdomains_puwE_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (981-1048). E-value: 4.4e-15.
                     Score: 48.0. Matches aSDomain:
                     nrpspksdomains_puwE_PP-binding.1"
                     /NRPS_PKS="Domain: Aminotran_3 (1261-1580). E-value:
                     1.6e-54. Score: 177.1. Matches aSDomain:
                     nrpspksdomains_puwE_Aminotran_3.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2053-2337). E-value:
                     3e-83. Score: 271.2. Matches aSDomain:
                     nrpspksdomains_puwE_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2503-2904). E-value:
                     2.2e-116. Score: 380.8. Matches aSDomain:
                     nrpspksdomains_puwE_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (3007-3075). E-value: 1.6e-23.
                     Score: 74.6. Matches aSDomain: nrpspksdomains_puwE_PCP.1"
                     /codon_start=1
                     /gene="puwE"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /note="NRPS; non-ribosomal peptide synthetase"
                     /product="PuwE"
                     /protein_id="AXN93613.1"
                     /sec_met_domain="mod_KS (E-value: 1.6e-191, bitscore:
                     626.5, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 2.6e-211, bitscore:
                     691.7, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 2.1e-167, bitscore:
                     547.0, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.4e-98, bitscore:
                     319.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1e-163, bitscore: 534.8,
                     seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 7.2e-188, bitscore:
                     614.5, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 2.9e-65, bitscore: 210.3,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.4e-113, bitscore:
                     369.0, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_3 (E-value: 9.1e-58, bitscore:
                     185.5, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1e-65, bitscore:
                     211.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.6e-125, bitscore:
                     407.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.7e-18, bitscore:
                     54.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSETTEQMTASQRMLLALKEARAKLEAFDRAKTEPIAIIGIGCR
                     FPGGANNPETFWQLLRDGVDAITEVPRSRWNIDEYYDPNPETPGKVYTRYGGFLENVDQ
                     FDPQFFGISPREAVSMNPQQRLLLEVAWEALEEAGINPKQLVNSLTGVFLGVGPNDYAK
                     LRMNADKAENITAHDGTGNGLCFASGRLSYVLGLQGPNLAMDTSCSSSLVAVHLASQSL
                     RAGECNLAIAGGVNLNLFPETTLFLSRTHALAPDGRCKTFDAAADGFGRSEGCGVIILK
                     RLSDALADGDCIWATIRGSAVNHDGPSSGLTVPNQLAQEQLIQQALDNAKVTPAQVTYI
                     EAHGTGTSLGDPIEVGALASVFCRQRSPEEPLVIGSVKTNLGHLEAAAGIAGLIKTVLA
                     LHHGEIPPHLHFHQPSPHIPWENLPVIVPTQPTPWQPKDKSRIAGVSSFGMSGTNVHIV
                     LESPVETLHATSVNSQQKNECPVHLLALSAKTGEALKELARNYTKYLQIHPQISLADLC
                     FTANTGRSHFEHRLAVVTDSVAKLQTQLSAFAENNPAEGLLHHHLTQRKTSKIAFLFTG
                     QGSQYLGMGKQLYDTQPVFRETLDHCDKILQPYLEKPLLEILYPQSPVPQSPVNETAYT
                     QPALFALEYSLYKLWQSWGIKPTAVIGHSVGEYVAACVAGVFSLEDGLKLIAQRAKLMQ
                     SLPPGGSMVAVLADESTVRLAIQNYAQDVTIAAINAPENIVIAGKQESVQAVVAILEQE
                     SIKTRNLTVSHAFHSPLVEPILEEFAATLQQITFHAPQIPLISNVTGKVFSPGEIPDVA
                     YWQRHTRAPVRFMDGVKTLFELGCEIFLELGPKPVLVNLGKQCQTENSAIWLASLMPEK
                     SDFQVLPKSNHTGSTTPKKNEKNTSSPPNLSPVTCHLSPVSLHSLSTLYIQGVAINWQG
                     LQPDYPRQRLSLPTYPFQRQRYWIEHNNIPMNPTHENIPSVNTQRQEEILAQLRSLVGQ
                     VLQVPPDKIDVNTPFLEMGADSIFLMEGVRSIENSFGVKIAIRQFFEELATINALATYI
                     EQHIAVSVVSEGHRQELAIPKLVNDYSSESTTGQNFPSNLEEVSTQTVATIVRVAPSNS
                     ASNGNGAASSHSDTAIERIMAQQLQMMTQIMSEQLQVLRGTPASTQPNFTPTNGNGNSN
                     GKSKTTNGNGNGNGNGNSKGHHPPLPTPNSQLPTPNSALLNPHSQKHLEDLIQRYTQRT
                     QKSKQRAQASRHHLGDNRAVAGFRMGIKEMLYPIVGTRYQGAHFWDLDGNEYVDLAMGF
                     GTHLFGHGAPFLIAAINEQLQKGVAVGPQPELALETAELLCELTGAERATFCQSGSESV
                     MVALRLARTATKRDRIAIFTGSYHGHFDGVLAQPEGMSSVPLGNGIAANTVKDVLVLNY
                     GDPKALEILQAQMHTLAAVMVEPVQSRFPNLQPREFLQELRHLTEAAGTALIFDEIMTG
                     FRIHPGGAQAHFGVKADLATYSKIFGGGLPLAAVAGKAKFMDGIDGGYWQFGDQSYPQA
                     DRTFFAGTFNKHPLAMATCRAALKYLKEQGVQLQTNLNARTAYLVEQLNHIFTEQQIDI
                     RVVNFGSLFRFVFTANMDVFFYHLLEKGVYIWEGRTCFLSTAHTDSDIEWIIQAVRDSI
                     TEMRSGGFFPHTQQENVTVKKSPASLPTANLNQPVNKAGFWERRKQKTTPREKTNYIPS
                     QKVQFSLYYFGNYESEFSHDKYDLLFTGAKFGDKNGFSAVWIPERHFHAFGGFSPNPSV
                     IAAAIARETQNIQIRSGSVVLPIHHPIRVVEEWSVVDNLSQGRVGISFASGWNPNDFVL
                     APQSFGKHRELMFQQMETVRKLWRGDSIQVQNGVGQTVSVEVFPKPMQAELQDWITIVN
                     NPDTYIKAGEMGAGVLTNLMGQSVEDLAENIALYRESLAQHGYDPSVGRVTVLLHTFVG
                     KDLEQTRQQAREPLCKYFKSSLALFQNLVKTQGLGIDFDSLSEDDQDYILSSACDRYIQ
                     SSALIGTPETCAQVVAKLQAIGVDEIACLIDFGVNPTAVVASLPELNDLRELYQNRPFF
                     ITAPLSTAQKQLWVLAQLSKEASTAYNESVSLKLQGKLNLPALTQAMQQIVNRHEALRT
                     SISPEGDVQQIFPFDLSSETPPLRASAPLRELTPEPFDLTKAPLFRLHLIQLSPEEHRL
                     TLTGHHIIVDGWSVGVILQELSTLYTAICQGKKCQLPTPMQYREYINWQIQQSQTEEMA
                     THEQYWLQKFADTIPALDLPSDRTRTPIKTYRGSKQSLLLHSEIGRAIKKVSLEQGCTL
                     FMTLLAVYTTLLHRLTGQSNIIVGIPTAGRSLPGSDSLVGYCAHVLPISSDYQSTTPFS
                     EYLLAIRNVLLEAYQHQDYPFAELIQKLNLNPDASRSPLVTVTFNLDRSITLPKLDELE
                     TSWFTQPINSTDYDIHWNITQIEDELILDCHYNTDLFDATTIERWLGHFQTLLTAIIAN
                     PRQPVGELPLLTATELQQLLVDWNATQTDYPADKCIHQIFEAQVEKTPDAVAVIGDREE
                     LTYAELNNRANQVAHYLRRQGVESGVLVGICMQRSLDFIVGVLGILKAGGVYVPLDPEY
                     PQERLAWMLEDVQPQVLLTQTDLIDRLPTFTNILSVDAAAIKKESTENLDTEVTADNLA
                     YIMYTSGSTGKPKGVSIPHRGVVRLVKATDYLSFTSEETWLQLAPISFDAATLEIWGSL
                     LNGSKLVIMPIPKPSLEEIGQIIQQHQITTLWLTASLFHLIVDERIEDLKTVRQLIAGG
                     DVLSIPHVKKVLQHLPQIRLVNGYGPTENTTFTCCYPITSDTNLDSSVPIGRPIANTQV
                     YILDPNLQPVPIGVWGELHTGGAGLAQGYWKRPDLTQEKFIQLGVENSTITYPQSLTLY
                     KTGDLTRYRPDGTIEFRGRIDQQIKIRGFRIELGEIETKLATHPQIKQTVVTTQADTLI
                     AYFIPEAEAPTNSELRHYLKQQLPDYMLPSAFVCLDTFPLTPNGKVDRKALPEADLAKQ
                     AHVQYIAPRTEKEQAIATIIASVLNLEKVGIADNFFEIGGNSLNAMQVTSRLRQTFGVE
                     LPLRQMLESPTVMELSTYIEQIFSTIQKLQSTPVELSENREEIEV"
     aSDomain        28466..29740
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="3.30E-187"
                     /label="puwE_PKS_KS.1"
                     /locus_tag="puwE"
                     /protein_end="461"
                     /protein_start="36"
                     /score="614.5"
                     /tool="antismash"
                     /translation="IAIIGIGCRFPGGANNPETFWQLLRDGVDAITEVPRSRWNIDEYY
                     DPNPETPGKVYTRYGGFLENVDQFDPQFFGISPREAVSMNPQQRLLLEVAWEALEEAGI
                     NPKQLVNSLTGVFLGVGPNDYAKLRMNADKAENITAHDGTGNGLCFASGRLSYVLGLQG
                     PNLAMDTSCSSSLVAVHLASQSLRAGECNLAIAGGVNLNLFPETTLFLSRTHALAPDGR
                     CKTFDAAADGFGRSEGCGVIILKRLSDALADGDCIWATIRGSAVNHDGPSSGLTVPNQL
                     AQEQLIQQALDNAKVTPAQVTYIEAHGTGTSLGDPIEVGALASVFCRQRSPEEPLVIGS
                     VKTNLGHLEAAAGIAGLIKTVLALHHGEIPPHLHFHQPSPHIPWENLPVIVPTQPTPWQ
                     PKDKSRIAGVSSFGMSGTNVHIVLES"
     aSModule        28466..33097
                     /complete
                     /domains="nrpspksdomains_puwE_PKS_KS.1"
                     /domains="nrpspksdomains_puwE_PKS_AT.1"
                     /domains="nrpspksdomains_puwE_PP-binding.1"
                     /domains="nrpspksdomains_puwE_Aminotran_3.1"
                     /locus_tags="puwE"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       28952..28999
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0001"
                     /evalue="9.70E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="puwE"
                     /protein_end="214"
                     /protein_start="198"
                     /score="14.7"
                     /tool="antismash"
                     /translation="GPNLAMDTSCSSSLVA"
     CDS_motif       29141..29179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0002"
                     /evalue="9.00E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="puwE"
                     /protein_end="274"
                     /protein_start="261"
                     /score="9.5"
                     /tool="antismash"
                     /translation="FDAAADGFGRSEG"
     CDS_motif       29372..29419
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0003"
                     /evalue="2.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="puwE"
                     /protein_end="354"
                     /protein_start="338"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YIEAHGTGTSLGDPIE"
     CDS_motif       29480..29524
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0004"
                     /evalue="1.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="puwE"
                     /protein_end="389"
                     /protein_start="374"
                     /score="11.2"
                     /tool="antismash"
                     /translation="GSVKTNLGHLEAAAG"
     aSDomain        30074..30955
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_PKS_AT.1"
                     /evalue="6.40E-113"
                     /label="puwE_PKS_AT.1"
                     /locus_tag="puwE"
                     /protein_end="866"
                     /protein_start="572"
                     /score="369.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYLGMGKQLYDTQPVFRETLDHCDKILQPYLEKPLLEI
                     LYPQSPVPQSPVNETAYTQPALFALEYSLYKLWQSWGIKPTAVIGHSVGEYVAACVAGV
                     FSLEDGLKLIAQRAKLMQSLPPGGSMVAVLADESTVRLAIQNYAQDVTIAAINAPENIV
                     IAGKQESVQAVVAILEQESIKTRNLTVSHAFHSPLVEPILEEFAATLQQITFHAPQIPL
                     ISNVTGKVFSPGEIPDVAYWQRHTRAPVRFMDGVKTLFELGCEIFLELGPKPVLVNLGK
                     QCQTENSAIWLAS"
     CDS_motif       30077..30124
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0005"
                     /evalue="1.20E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="puwE"
                     /protein_end="589"
                     /protein_start="573"
                     /score="17.8"
                     /tool="antismash"
                     /translation="FTGQGSQYLGMGKQLY"
     CDS_motif       30257..30313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0006"
                     /evalue="1.30E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="puwE"
                     /protein_end="652"
                     /protein_start="633"
                     /score="12.0"
                     /tool="antismash"
                     /translation="YTQPALFALEYSLYKLWQS"
     CDS_motif       30317..30439
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0007"
                     /evalue="6.80E-29"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="puwE"
                     /protein_end="694"
                     /protein_start="653"
                     /score="92.4"
                     /tool="antismash"
                     /translation="GIKPTAVIGHSVGEYVAACVAGVFSLEDGLKLIAQRAKLMQ"
     CDS_motif       30533..30571
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0008"
                     /evalue="2.70E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="puwE"
                     /protein_end="738"
                     /protein_start="725"
                     /score="11.1"
                     /tool="antismash"
                     /translation="AAINAPENIVIAG"
     CDS_motif       30725..30757
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0009"
                     /evalue="3.50E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="puwE"
                     /protein_end="800"
                     /protein_start="789"
                     /score="10.1"
                     /tool="antismash"
                     /translation="PQIPLISNVTG"
     CDS_motif       30794..30829
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0010"
                     /evalue="1.00E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="puwE"
                     /protein_end="824"
                     /protein_start="812"
                     /score="12.6"
                     /tool="antismash"
                     /translation="YWQRHTRAPVRF"
     aSDomain        31301..31501
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_PP-binding.1"
                     /evalue="4.40E-15"
                     /label="puwE_PP-binding.1"
                     /locus_tag="puwE"
                     /protein_end="1048"
                     /protein_start="981"
                     /score="48.0"
                     /tool="antismash"
                     /translation="QLRSLVGQVLQVPPDKIDVNTPFLEMGADSIFLMEGVRSIENSFG
                     VKIAIRQFFEELATINALATYI"
     aSDomain        32141..33097
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_Aminotran_3.1"
                     /evalue="1.60E-54"
                     /label="puwE_Aminotran_3.1"
                     /locus_tag="puwE"
                     /protein_end="1580"
                     /protein_start="1261"
                     /score="177.1"
                     /tool="antismash"
                     /translation="TRYQGAHFWDLDGNEYVDLAMGFGTHLFGHGAPFLIAAINEQLQK
                     GVAVGPQPELALETAELLCELTGAERATFCQSGSESVMVALRLARTATKRDRIAIFTGS
                     YHGHFDGVLAQPEGMSSVPLGNGIAANTVKDVLVLNYGDPKALEILQAQMHTLAAVMVE
                     PVQSRFPNLQPREFLQELRHLTEAAGTALIFDEIMTGFRIHPGGAQAHFGVKADLATYS
                     KIFGGGLPLAAVAGKAKFMDGIDGGYWQFGDQSYPQADRTFFAGTFNKHPLAMATCRAA
                     LKYLKEQGVQLQTNLNARTAYLVEQLNHIFTEQQIDIR"
     aSDomain        34517..35368
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.00E-83"
                     /label="puwE_Condensation_LCL.1"
                     /locus_tag="puwE"
                     /protein_end="2337"
                     /protein_start="2053"
                     /score="271.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIVDG"
                     /tool="antismash"
                     /translation="APLSTAQKQLWVLAQLSKEASTAYNESVSLKLQGKLNLPALTQAM
                     QQIVNRHEALRTSISPEGDVQQIFPFDLSSETPPLRASAPLRELTPEPFDLTKAPLFRL
                     HLIQLSPEEHRLTLTGHHIIVDGWSVGVILQELSTLYTAICQGKKCQLPTPMQYREYIN
                     WQIQQSQTEEMATHEQYWLQKFADTIPALDLPSDRTRTPIKTYRGSKQSLLLHSEIGRA
                     IKKVSLEQGCTLFMTLLAVYTTLLHRLTGQSNIIVGIPTAGRSLPGSDSLVGYCAHVLP
                     ISS"
     aSModule        34517..37582
                     /complete
                     /domains="nrpspksdomains_puwE_Condensation_LCL.1"
                     /domains="nrpspksdomains_puwE_AMP-binding.1"
                     /domains="nrpspksdomains_puwE_PCP.1"
                     /locus_tags="puwE"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       34580..34693
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0011"
                     /evalue="1.70E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwE"
                     /protein_end="2112"
                     /protein_start="2074"
                     /score="52.5"
                     /tool="antismash"
                     /translation="TAYNESVSLKLQGKLNLPALTQAMQQIVNRHEALRTSI"
     CDS_motif       34877..34939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0012"
                     /evalue="9.00E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwE"
                     /protein_end="2194"
                     /protein_start="2173"
                     /score="34.2"
                     /tool="antismash"
                     /translation="HHIIVDGWSVGVILQELSTLY"
     CDS_motif       35279..35362
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0013"
                     /evalue="2.30E-05"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwE"
                     /protein_end="2335"
                     /protein_start="2307"
                     /score="16.9"
                     /tool="antismash"
                     /translation="IIVGIPTAGRSLPGSDSLVGYCAHVLPI"
     CDS_motif       35414..35533
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0014"
                     /evalue="3.20E-13"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwE"
                     /protein_end="2392"
                     /protein_start="2352"
                     /score="42.0"
                     /tool="antismash"
                     /translation="RNVLLEAYQHQDYPFAELIQKLNLNPDASRSPLVTVTFNL"
     aSDomain        35867..37069
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_AMP-binding.1"
                     /evalue="2.20E-116"
                     /label="puwE_AMP-binding.1"
                     /locus_tag="puwE"
                     /protein_end="2904"
                     /protein_start="2503"
                     /score="380.8"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEAQVEKTPDAVAVIGDREELTYAELNNRANQVAHYLRRQGVESG
                     VLVGICMQRSLDFIVGVLGILKAGGVYVPLDPEYPQERLAWMLEDVQPQVLLTQTDLID
                     RLPTFTNILSVDAAAIKKESTENLDTEVTADNLAYIMYTSGSTGKPKGVSIPHRGVVRL
                     VKATDYLSFTSEETWLQLAPISFDAATLEIWGSLLNGSKLVIMPIPKPSLEEIGQIIQQ
                     HQITTLWLTASLFHLIVDERIEDLKTVRQLIAGGDVLSIPHVKKVLQHLPQIRLVNGYG
                     PTENTTFTCCYPITSDTNLDSSVPIGRPIANTQVYILDPNLQPVPIGVWGELHTGGAGL
                     AQGYWKRPDLTQEKFIQLGVENSTITYPQSLTLYKTGDLTRYRPDGTIEFRGRIDQQIK
                     IR"
     CDS_motif       36053..36094
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0015"
                     /evalue="3.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwE"
                     /protein_end="2579"
                     /protein_start="2565"
                     /score="17.1"
                     /tool="antismash"
                     /translation="LGILKAGGVYVPLD"
     CDS_motif       36278..36337
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0016"
                     /evalue="2.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="puwE"
                     /protein_end="2660"
                     /protein_start="2640"
                     /score="29.1"
                     /tool="antismash"
                     /translation="AYIMYTSGSTGKPKGVSIPH"
     CDS_motif       36842..36931
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0017"
                     /evalue="7.40E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="puwE"
                     /protein_end="2858"
                     /protein_start="2828"
                     /score="47.0"
                     /tool="antismash"
                     /translation="PIGVWGELHTGGAGLAQGYWKRPDLTQEKF"
     CDS_motif       37034..37099
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0018"
                     /evalue="1.50E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="puwE"
                     /protein_end="2914"
                     /protein_start="2892"
                     /score="33.1"
                     /tool="antismash"
                     /translation="FRGRIDQQIKIRGFRIELGEIE"
     aSDomain        37379..37582
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_PCP.1"
                     /evalue="1.60E-23"
                     /label="puwE_PCP.1"
                     /locus_tag="puwE"
                     /protein_end="3075"
                     /protein_start="3007"
                     /score="74.6"
                     /tool="antismash"
                     /translation="EQAIATIIASVLNLEKVGIADNFFEIGGNSLNAMQVTSRLRQTFG
                     VELPLRQMLESPTVMELSTYIEQ"
     gene            37654..46308
                     /gene="puwF"
     CDS             37654..46308
                     /NRPS_PKS="Domain: Condensation_LCL (80-375). E-value:
                     2.1e-123. Score: 403.0. Matches aSDomain:
                     nrpspksdomains_puwF_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (539-942). E-value:
                     2.3e-120. Score: 393.8. Matches aSDomain:
                     nrpspksdomains_puwF_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1050-1117). E-value: 9.7e-26.
                     Score: 81.8. Matches aSDomain: nrpspksdomains_puwF_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1146-1446). E-value:
                     2.3e-65. Score: 212.6. Matches aSDomain:
                     nrpspksdomains_puwF_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1608-2009). E-value:
                     2.1e-112. Score: 367.7. Matches aSDomain:
                     nrpspksdomains_puwF_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2116-2185). E-value: 7.6e-25.
                     Score: 78.9. Matches aSDomain: nrpspksdomains_puwF_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (2205-2505). E-value:
                     8.7e-125. Score: 407.6. Matches aSDomain:
                     nrpspksdomains_puwF_Condensation_LCL.2"
                     /codon_start=1
                     /gene="puwF"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /note="NRPS; non-ribosomal peptide synthetase"
                     /product="PuwF"
                     /protein_id="AXN93614.1"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-131, bitscore:
                     427.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.9e-17, bitscore:
                     52.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.3e-89, bitscore:
                     287.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPIEEFLSELGNLDIKLWVEDNPNSSQGVKLRCNAPSGRLTPEI
                     RANLSDRKAEIISFFQRVNLTSEVESIPTVARDNGNLPLSWSQQRLWFLYQMEGASATY
                     NMPAAVQMTGVLDISALEQALQEIIRRHEVLRTSFAKVDGHAVQVIHPHANLTLPIVDL
                     QGCSDQVKQLAILDAEKPFDLTQAPLMRVTLLKLSEQSHVLLMNMHHIVADGWSIGILI
                     QEISTLYTVFIQSKPSPLPALPIQYADFAVWQRQWLQGEVFSQKINYWQKQLADAPPLL
                     ELPTDRPRPAIQTFRGSSRDFPLPLELTEQLNRLSQKFGVTLFMTLEAAFVTLLHRYSG
                     QTDILIGSPIANRDRPEIDTLIGFFINTLVLRSRLENNPPFIELLQQVKQVALDAYAHQ
                     EVPFEQIVDILQLKRNLSHTPLFQVMFALQNAPMGNLELPGLQLSQLPIEAITSKFDLT
                     LSMTETPQGLIGNWEYNTDLFDSETITRMAGHFQNLLTAILANPQQTVQELALLSNAER
                     QQILGDGYSTAEYIVNQCLHQRFEEQAEKTPDAIAVTFADQHLTYAQLNTRANQLAHYL
                     QTLGVAPDVLVGICVERSLEMMIGLLGILKAGGAYVPLDPEYPPERLAFMLDDSQVSVL
                     LTQAKWLENLPVTNAKTVCLDQDWEDIHTHSVENPQIGVLPENLAYVIYTSGSTGKPKG
                     VLVNHCNVMRLFAATHDWFNFDASDVWTLFHSYAFDFSVWEMWGALLYGGRLVVVPFWV
                     SRDPEELYQMLHQEGVTVLNQTPSAFRQLIWAEEEQGISNLSLRWVIFGGEALDPTSLL
                     PWFERHGDVTPQLVNMYGITETTVHVTFRRLSMADAGSPSSVIGVPIPDLRLYILDEHL
                     QPVPVGVRGEMYVGGAGVTRGYLHRPELTQQRFLTTPYSPRPLYKTGDLARYLPDGSIE
                     YLGRIDDQVKIRGFRIELGEIEAKLATHPQVRQTVVLVQADTPDNKRLVAYFVAEGESP
                     SSGELRDYLKQQLPDYMIPAVFVCLDAFPLTANGKLDRRMLPVPEVRPELNSGFVAPQT
                     PEEELLANIWAKVLGVSQVGIHDNFFELGGDSIRSIQILAQANQVGLDFSLQQLFQHQT
                     IAELATLVSKEVSFTVTPQTSPFSLVAEVDKEKLPAKLADAYPLTALQAGMVFHSELSL
                     DSAIYHDVFSFHMRATLDLSVLQTAIEQLIFRHAVLRTSFELSGFSEPLQLVHQNIDVP
                     LQVDDISHLTTAEQQAAINNWIETEKYHSFDWKKPPLLRFYVHRRSTETFNLSFSFHHA
                     ILDGWSVAALLTELWQEYINLLKHQPSSHSAIRTLAFGDFVALERQALQSEATQQYWLE
                     QLADVTITELPRWPESHRKDAKAEIDIEEVAITAELSDGLKQLASKAGVPLKSVLLAAH
                     VRVLNLLTNQTDVLTGLVANGRPEDADGEKILGLFLNTLPLRSHLGGGTWLELIQQTFQ
                     AEQAALPHRRYPLAEMQRLCGGEQLFETSFNFVHFHVYQGILGLKESEVLDYQAFEQTN
                     LTLVAHFSVNPVSSQLNLALNYQTNQLCREQVESISTYYINALMAMVAAPSALYQNQSL
                     LSPQEQHQLLDEWNATESSYDDSLCLHQLFAAQVQKTPNAIAVTYEQQHLTYAQLNQRA
                     NQLAHHLQTLGVKPDTLVGICVERSLEMVVGLLGILKAGGAFVPLDPAYPRDRLQYLLE
                     DSQVPVLLTQSHLLDILPEHQQVICLDTDWQAISQQSQANPVSQVKSTNLAYIIYTSGS
                     TGKPKGTMIIHQGVVNYLSWCTEAYAVADGYGAPVQSSFAFDATITSLFSPLMVGKQVV
                     LLPERQEIEALCSVLRSKTQFSLVKLTPAHLELLNQIIPPAAAAGQTNAFVIGGEALLG
                     KTLQFWRQNAPQTRLINEYGPTETVVGCCIYEVTDDTSLTEGILIGRPIANTQLYILDE
                     YLQPVPIGVRGELYIGGAGVARGYLNRPELTKEKFISHPFIHEPGARLYKTGDLARYQP
                     DGNIEYLGRTDHQVKVRGFRIELGEIEQAIAKYPQIREVVVMVREDQPGDQRLVAYIVA
                     TEPPTDSELREHLKKQLPDYMIPTAFVYLDVFPLTANGKLDRQSLPVPTQIQKITTNFV
                     LPRTDTEKAIADLFSLLLGVKNVSIYDNFFELGGHSLIATQVISRLRETFQIELPLRVL
                     FESPRVIELAEVINSQRQTNLELTAPALTPVSRENLDIPLSWAQQRLWFLEQLEGGSAT
                     YNVPAAFQLEGRLNVTALEQALEEIIRRHETLRTCFRLVNGTPVQFIDTNATITLKVTD
                     LQQLPTPEQTTEVQRLAVLAAETPFNLQHAPLFRVTLLPLGEESHVLLMTIHHIISDGW
                     SVGIFIQELSTLYQAFSAGKPAPLPALPIQYADFAIWQRQWLSGELLKAKLNYWQQQLA
                     DAPPLLELPTDRPRPAIKTFRGNKQDFAISLQLSEGIKDLSQQHGVTLFMTLQAAFATL
                     LHRYSGQTDILVGTPIANRNRAEIEPLIGFFVNTLVLRTQICDNPSFAELLQQVKRVAL
                     DGYAHQDVPFEQVVEVLQPERNLSYTPLFQVMFALQNAPLGLDNLELAGLSLTPLLIET
                     VTAKFDLTLSMEETPEGLISTWEYNTDLFDDETITRMAGHFQNILTAILANPQQTVQEL
                     ALLSDTERQQILGDGKPTAEYVVNQCLHQLFEEQVQKTPDAIAVTFADQHLTYAQLNTR
                     ANQLAHYLQTLGVAPDVLVGICVERSLEMMIGLLGILKAGGAYVPLDPEYPPERLAFML
                     DDSQVSVLLTQAKWLENLPVTNAKTVCLDQDWEDIHTHSVENPQIGVLPENLAYVIYTS
                     GSTGKPKGVLVNHCNVMRLFAATHLTLMLAMCGRCSIPMLLILCVGNVGSVVVWRSISG
                     CAFLCES"
     aSDomain        37894..38778
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.10E-123"
                     /label="puwF_Condensation_LCL.1"
                     /locus_tag="puwF"
                     /protein_end="375"
                     /protein_start="80"
                     /score="403.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVADG"
                     /tool="antismash"
                     /translation="NLPLSWSQQRLWFLYQMEGASATYNMPAAVQMTGVLDISALEQAL
                     QEIIRRHEVLRTSFAKVDGHAVQVIHPHANLTLPIVDLQGCSDQVKQLAILDAEKPFDL
                     TQAPLMRVTLLKLSEQSHVLLMNMHHIVADGWSIGILIQEISTLYTVFIQSKPSPLPAL
                     PIQYADFAVWQRQWLQGEVFSQKINYWQKQLADAPPLLELPTDRPRPAIQTFRGSSRDF
                     PLPLELTEQLNRLSQKFGVTLFMTLEAAFVTLLHRYSGQTDILIGSPIANRDRPEIDTL
                     IGFFINTLVLRSRL"
     aSModule        37894..41004
                     /complete
                     /domains="nrpspksdomains_puwF_Condensation_LCL.1"
                     /domains="nrpspksdomains_puwF_AMP-binding.1"
                     /domains="nrpspksdomains_puwF_PCP.1"
                     /locus_tags="puwF"
                     /monomer_pairings="Thr -> Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       37906..37935
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0001"
                     /evalue="2.70E-01"
                     /label="C1_LCL_004-017"
                     /locus_tag="puwF"
                     /protein_end="94"
                     /protein_start="84"
                     /score="4.7"
                     /tool="antismash"
                     /translation="SWSQQRLWFL"
     CDS_motif       37957..38073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0002"
                     /evalue="1.60E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwF"
                     /protein_end="140"
                     /protein_start="101"
                     /score="62.3"
                     /tool="antismash"
                     /translation="ATYNMPAAVQMTGVLDISALEQALQEIIRRHEVLRTSFA"
     CDS_motif       38275..38340
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0003"
                     /evalue="5.40E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwF"
                     /protein_end="229"
                     /protein_start="207"
                     /score="38.1"
                     /tool="antismash"
                     /translation="MHHIVADGWSIGILIQEISTLY"
     CDS_motif       38389..38427
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0004"
                     /evalue="3.50E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="puwF"
                     /protein_end="258"
                     /protein_start="245"
                     /score="19.4"
                     /tool="antismash"
                     /translation="QYADFAVWQRQWL"
     CDS_motif       38680..38769
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0005"
                     /evalue="1.70E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwF"
                     /protein_end="372"
                     /protein_start="342"
                     /score="52.5"
                     /tool="antismash"
                     /translation="DILIGSPIANRDRPEIDTLIGFFINTLVLR"
     CDS_motif       38818..38937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0006"
                     /evalue="7.80E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwF"
                     /protein_end="428"
                     /protein_start="388"
                     /score="73.0"
                     /tool="antismash"
                     /translation="KQVALDAYAHQEVPFEQIVDILQLKRNLSHTPLFQVMFAL"
     aSDomain        39271..40479
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_AMP-binding.1"
                     /evalue="2.30E-120"
                     /label="puwF_AMP-binding.1"
                     /locus_tag="puwF"
                     /protein_end="942"
                     /protein_start="539"
                     /score="393.8"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEEQAEKTPDAIAVTFADQHLTYAQLNTRANQLAHYLQTLGVAPD
                     VLVGICVERSLEMMIGLLGILKAGGAYVPLDPEYPPERLAFMLDDSQVSVLLTQAKWLE
                     NLPVTNAKTVCLDQDWEDIHTHSVENPQIGVLPENLAYVIYTSGSTGKPKGVLVNHCNV
                     MRLFAATHDWFNFDASDVWTLFHSYAFDFSVWEMWGALLYGGRLVVVPFWVSRDPEELY
                     QMLHQEGVTVLNQTPSAFRQLIWAEEEQGISNLSLRWVIFGGEALDPTSLLPWFERHGD
                     VTPQLVNMYGITETTVHVTFRRLSMADAGSPSSVIGVPIPDLRLYILDEHLQPVPVGVR
                     GEMYVGGAGVTRGYLHRPELTQQRFLTTPYSPRPLYKTGDLARYLPDGSIEYLGRIDDQ
                     VKIR"
     CDS_motif       39457..39498
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0007"
                     /evalue="9.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="puwF"
                     /protein_end="615"
                     /protein_start="601"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       39691..39750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0008"
                     /evalue="3.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwF"
                     /protein_end="699"
                     /protein_start="679"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVLVNH"
     CDS_motif       40276..40365
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0009"
                     /evalue="1.50E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="puwF"
                     /protein_end="904"
                     /protein_start="874"
                     /score="49.2"
                     /tool="antismash"
                     /translation="PVGVRGEMYVGGAGVTRGYLHRPELTQQRF"
     CDS_motif       40444..40509
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0010"
                     /evalue="1.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwF"
                     /protein_end="952"
                     /protein_start="930"
                     /score="39.9"
                     /tool="antismash"
                     /translation="YLGRIDDQVKIRGFRIELGEIE"
     aSDomain        40804..41004
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_PCP.1"
                     /evalue="9.70E-26"
                     /label="puwF_PCP.1"
                     /locus_tag="puwF"
                     /protein_end="1117"
                     /protein_start="1050"
                     /score="81.8"
                     /tool="antismash"
                     /translation="EELLANIWAKVLGVSQVGIHDNFFELGGDSIRSIQILAQANQVGL
                     DFSLQQLFQHQTIAELATLVSK"
     aSDomain        41092..41991
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.30E-65"
                     /label="puwF_Condensation_DCL.1"
                     /locus_tag="puwF"
                     /protein_end="1446"
                     /protein_start="1146"
                     /score="212.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHAILDG"
                     /tool="antismash"
                     /translation="DAYPLTALQAGMVFHSELSLDSAIYHDVFSFHMRATLDLSVLQTA
                     IEQLIFRHAVLRTSFELSGFSEPLQLVHQNIDVPLQVDDISHLTTAEQQAAINNWIETE
                     KYHSFDWKKPPLLRFYVHRRSTETFNLSFSFHHAILDGWSVAALLTELWQEYINLLKHQ
                     PSSHSAIRTLAFGDFVALERQALQSEATQQYWLEQLADVTITELPRWPESHRKDAKAEI
                     DIEEVAITAELSDGLKQLASKAGVPLKSVLLAAHVRVLNLLTNQTDVLTGLVANGRPED
                     ADGEKILGLFLNTLPLRSH"
     aSModule        41092..44208
                     /complete
                     /domains="nrpspksdomains_puwF_Condensation_DCL.1"
                     /domains="nrpspksdomains_puwF_AMP-binding.2"
                     /domains="nrpspksdomains_puwF_PCP.2"
                     /locus_tags="puwF"
                     /monomer_pairings="Asn -> Asn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       41098..41139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0011"
                     /evalue="7.10E-03"
                     /label="C1_DCL_004-017"
                     /locus_tag="puwF"
                     /protein_end="1162"
                     /protein_start="1148"
                     /score="9.1"
                     /tool="antismash"
                     /translation="YPLTALQAGMVFHS"
     CDS_motif       41158..41271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0012"
                     /evalue="2.90E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwF"
                     /protein_end="1206"
                     /protein_start="1168"
                     /score="26.1"
                     /tool="antismash"
                     /translation="AIYHDVFSFHMRATLDLSVLQTAIEQLIFRHAVLRTSF"
     CDS_motif       41494..41553
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0013"
                     /evalue="2.40E-07"
                     /label="C3_DCL_135-156"
                     /locus_tag="puwF"
                     /protein_end="1300"
                     /protein_start="1280"
                     /score="23.3"
                     /tool="antismash"
                     /translation="FHHAILDGWSVAALLTELWQ"
     CDS_motif       41893..41985
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0014"
                     /evalue="9.40E-08"
                     /label="C5_DCL_263-294"
                     /locus_tag="puwF"
                     /protein_end="1444"
                     /protein_start="1413"
                     /score="24.6"
                     /tool="antismash"
                     /translation="DVLTGLVANGRPEDADGEKILGLFLNTLPLR"
     CDS_motif       42046..42132
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0015"
                     /evalue="2.30E-04"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="puwF"
                     /protein_end="1493"
                     /protein_start="1464"
                     /score="13.8"
                     /tool="antismash"
                     /translation="AALPHRRYPLAEMQRLCGGEQLFETSFNF"
     aSDomain        42478..43680
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_AMP-binding.2"
                     /evalue="2.10E-112"
                     /label="puwF_AMP-binding.2"
                     /locus_tag="puwF"
                     /protein_end="2009"
                     /protein_start="1608"
                     /score="367.7"
                     /specificity="substrate consensus: Asn"
                     /tool="antismash"
                     /translation="FAAQVQKTPNAIAVTYEQQHLTYAQLNQRANQLAHHLQTLGVKPD
                     TLVGICVERSLEMVVGLLGILKAGGAFVPLDPAYPRDRLQYLLEDSQVPVLLTQSHLLD
                     ILPEHQQVICLDTDWQAISQQSQANPVSQVKSTNLAYIIYTSGSTGKPKGTMIIHQGVV
                     NYLSWCTEAYAVADGYGAPVQSSFAFDATITSLFSPLMVGKQVVLLPERQEIEALCSVL
                     RSKTQFSLVKLTPAHLELLNQIIPPAAAAGQTNAFVIGGEALLGKTLQFWRQNAPQTRL
                     INEYGPTETVVGCCIYEVTDDTSLTEGILIGRPIANTQLYILDEYLQPVPIGVRGELYI
                     GGAGVARGYLNRPELTKEKFISHPFIHEPGARLYKTGDLARYQPDGNIEYLGRTDHQVK
                     VR"
     CDS_motif       42664..42705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0016"
                     /evalue="3.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwF"
                     /protein_end="1684"
                     /protein_start="1670"
                     /score="17.1"
                     /tool="antismash"
                     /translation="LGILKAGGAFVPLD"
     CDS_motif       42895..42954
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0017"
                     /evalue="3.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="puwF"
                     /protein_end="1767"
                     /protein_start="1747"
                     /score="28.9"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGTMIIH"
     CDS_motif       43468..43557
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0018"
                     /evalue="3.20E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="puwF"
                     /protein_end="1968"
                     /protein_start="1938"
                     /score="57.8"
                     /tool="antismash"
                     /translation="PIGVRGELYIGGAGVARGYLNRPELTKEKF"
     CDS_motif       43645..43710
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0019"
                     /evalue="4.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwF"
                     /protein_end="2019"
                     /protein_start="1997"
                     /score="37.8"
                     /tool="antismash"
                     /translation="YLGRTDHQVKVRGFRIELGEIE"
     aSDomain        44002..44208
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_PCP.2"
                     /evalue="7.60E-25"
                     /label="puwF_PCP.2"
                     /locus_tag="puwF"
                     /protein_end="2185"
                     /protein_start="2116"
                     /score="78.9"
                     /tool="antismash"
                     /translation="EKAIADLFSLLLGVKNVSIYDNFFELGGHSLIATQVISRLRETFQ
                     IELPLRVLFESPRVIELAEVINSQ"
     aSDomain        44269..45168
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="8.70E-125"
                     /label="puwF_Condensation_LCL.2"
                     /locus_tag="puwF"
                     /protein_end="2505"
                     /protein_start="2205"
                     /score="407.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="DIPLSWAQQRLWFLEQLEGGSATYNVPAAFQLEGRLNVTALEQAL
                     EEIIRRHETLRTCFRLVNGTPVQFIDTNATITLKVTDLQQLPTPEQTTEVQRLAVLAAE
                     TPFNLQHAPLFRVTLLPLGEESHVLLMTIHHIISDGWSVGIFIQELSTLYQAFSAGKPA
                     PLPALPIQYADFAIWQRQWLSGELLKAKLNYWQQQLADAPPLLELPTDRPRPAIKTFRG
                     NKQDFAISLQLSEGIKDLSQQHGVTLFMTLQAAFATLLHRYSGQTDILVGTPIANRNRA
                     EIEPLIGFFVNTLVLRTQI"
     CDS_motif       44281..44313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0020"
                     /evalue="4.00E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="puwF"
                     /protein_end="2220"
                     /protein_start="2209"
                     /score="7.0"
                     /tool="antismash"
                     /translation="SWAQQRLWFLE"
     CDS_motif       44332..44448
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0021"
                     /evalue="3.60E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwF"
                     /protein_end="2265"
                     /protein_start="2226"
                     /score="61.2"
                     /tool="antismash"
                     /translation="ATYNVPAAFQLEGRLNVTALEQALEEIIRRHETLRTCFR"
     CDS_motif       44665..44730
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0022"
                     /evalue="3.10E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwF"
                     /protein_end="2359"
                     /protein_start="2337"
                     /score="38.8"
                     /tool="antismash"
                     /translation="IHHIISDGWSVGIFIQELSTLY"
     CDS_motif       44779..44817
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0023"
                     /evalue="3.70E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="puwF"
                     /protein_end="2388"
                     /protein_start="2375"
                     /score="19.3"
                     /tool="antismash"
                     /translation="QYADFAIWQRQWL"
     CDS_motif       45070..45159
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0024"
                     /evalue="4.50E-18"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwF"
                     /protein_end="2502"
                     /protein_start="2472"
                     /score="57.5"
                     /tool="antismash"
                     /translation="DILVGTPIANRNRAEIEPLIGFFVNTLVLR"
     CDS_motif       45208..45327
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0025"
                     /evalue="4.90E-25"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwF"
                     /protein_end="2558"
                     /protein_start="2518"
                     /score="80.0"
                     /tool="antismash"
                     /translation="KRVALDGYAHQDVPFEQVVEVLQPERNLSYTPLFQVMFAL"
     CDS_motif       45853..45894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0026"
                     /evalue="9.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="puwF"
                     /protein_end="2747"
                     /protein_start="2733"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       46087..46146
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0027"
                     /evalue="3.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwF"
                     /protein_end="2831"
                     /protein_start="2811"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVLVNH"
     gene            46346..55273
                     /gene="puwG"
     CDS             46346..55273
                     /NRPS_PKS="Domain: PCP (297-363). E-value: 1.7e-25. Score:
                     81.0. Matches aSDomain: nrpspksdomains_puwG_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (391-694). E-value:
                     6.3e-64. Score: 207.9. Matches aSDomain:
                     nrpspksdomains_puwG_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (856-1257). E-value:
                     3.6e-111. Score: 363.6. Matches aSDomain:
                     nrpspksdomains_puwG_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1365-1432). E-value: 1.1e-23.
                     Score: 75.2. Matches aSDomain: nrpspksdomains_puwG_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1452-1751). E-value:
                     6.1e-123. Score: 401.5. Matches aSDomain:
                     nrpspksdomains_puwG_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1916-2311). E-value:
                     1.1e-114. Score: 375.2. Matches aSDomain:
                     nrpspksdomains_puwG_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2419-2484). E-value: 1.4e-25.
                     Score: 81.3. Matches aSDomain: nrpspksdomains_puwG_PCP.3"
                     /NRPS_PKS="Domain: Epimerization (2496-2800). E-value:
                     1.3e-161. Score: 531.0. Matches aSDomain:
                     nrpspksdomains_puwG_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2819-2969). E-value: 6e-47.
                     Score: 151.3. Matches aSDomain:
                     nrpspksdomains_puwG_TIGR01720.1"
                     /NRPS_PKS="Domain: NRPS-COM_Cterm (2952-2973). E-value:
                     1.5e-09. Score: 29.4. Matches aSDomain:
                     nrpspksdomains_puwG_NRPS-COM_Cterm.1"
                     /codon_start=1
                     /gene="puwG"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /note="NRPS; non-ribosomal peptide synthetase"
                     /product="PuwG"
                     /protein_id="AXN93615.1"
                     /sec_met_domain="Condensation (E-value: 1e-87, bitscore:
                     283.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.6e-125, bitscore:
                     407.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-16, bitscore:
                     50.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLNQTPSAFRQLIWVESSHRGGDERIALRWVIFGGEALDPTSL
                     LPWFERHGDACPQLVNMYGITETTVHVTFHQLTMADAGSPSSVIGVPIPDLRLYILDEH
                     LQPVPVGVRGEMYVGGAGVTRGYLNRPELTQERFIRLGTRDNTVTCHLSPVTYNPLYKT
                     GDLARYLADGNIEYLGRIDDQVKIRGFRIELGEIEAKLASHPQIRQTVVLVQADTPDNK
                     RLVAYFVADGESPSSGELRDYLKQQLPDYMIPAVFVSLDAFPLTANGKLDRRMLPVPEV
                     RPELDTGFVAPQNEKQELLASIWTEVLGVSQVGIHDNFFELGGDSIRSIQILAQANQVG
                     LDFSLQQLFQYQTIAELAELVSKEVSFTLTPQTSPFSLIAEIDKQKLAAGLEDAYPLTA
                     LQAGMVFHSELSADSAIYHDVFSFHLRATLDLPALHTAIEQLMARYAVLRTSFELSGFS
                     EPLQLVHQNVDVPLQVDDISDLTMAEQQAAIDAWIETEKYRHFDWTQPPLWRFDVHRRS
                     GETFNLSFSFHHAILDGWSVASLLTELWQQYLNLLKPNPIPNPQSPVPTLAFRDFVALE
                     RTALQSETTQQYWLEQLRDVTITELPRWPQSYLEEAEEEVSIQEVAISAELSDGLKQLA
                     RNASVPLKSVLLAAHLRVLNLLGNQADVLTGLVANGRPEDADGEKILGLFLNTLPLRSH
                     LGGGTWLELIQQTFQAEQAALPHRRYPLAEMQRLCGGEQLFETSFNFVHFHVYQGVLGL
                     EESQLLDSQTFEQTNFTLVANFGLDLVSSHVNLALSYKTNELCREQVESISTYYLNTLM
                     AMVAAPSALYQNQSLLSPTEQHQLLTDGNATESSYDDRLCLHQLFAAQVQKNTNAIAVT
                     YEQQHLTYAQLNQRANQLAHHLQTLGVKPDTLVGICVERSLEMVVGLLGILKAGGAFVP
                     LDPAYPRDRLQYLLEDSQVPVLLTQSHLLDILPEHQQVICLDTDWQAISQQSQANPVSQ
                     VKSTNLAYIIYTSGSTGKPKGTMIIHQGVVNYLSWCTEAYAVADGYGAPVQSSFAFDAT
                     ITSLFSPLMVGKQVVLLPERQEIEALCSVLRSKTQFSLVKLTPAHLELLNQIIPPAAAA
                     GQTNAFVIGGEALLGKTLQFWRENAPETRLINEYGPTETVVGCCIYEVTDDTSLTEGIL
                     IGRPIANTQLYILDEYLQPVPIGVRGELYIGGAGVARGYLNRPELTKEKFISHPFIHEP
                     GARLYKTGDLARYQPDGNIEYLGRTDHQVKVRGFRIELGEIETAVNQHPQVKQVAIIVR
                     EDQPGDQRLVAYLIPDGEAPTSDELRNALKQQLPDYMIPTAFVVLNTLPLTPNGKLDRN
                     ALPIPDINITSENFVLPRTQTEVLIADLFASLLGIKQVSIHDNFFALGGHSLLATQVIS
                     RLRVIFRIEVPLRLLFESPTVAELDQAIHKLQQTDSGLLSPPLVPVTRDNQPIPLSWSQ
                     QRLWFLAQLESSSGTYNVPAALQLQGYLNVAALEQALQEIVHRHEVLRTSFPTINGVPT
                     QVIVPAVTVTLPLIDLQGLPEQAEQVKQLTITNSQTTFDLAIAPLMRSQLLRLGEQSHI
                     LLINLHHIVCDGWSVGVFIQELSALYTAFTEEKPSPLPELAIQYADFAVWQRQWLSGEV
                     LEKKLNYWQQQLAGAPPLLELPIDRPRPPIQSYQGGYYGFTLDADLTAKLKSLSQKSSV
                     TLFMTLQAAFVTLLHRYSGQTDILVGTPIANRDRKETESLIGFFVNTLVLRTQITDNPK
                     FAELLQQVRRVSLEAYAYQDVPFEQVVEALQPERNLSHSPLFQVMFIWQNTPSQNFELP
                     GLSLTPLPIETVTAKFDLTLSMEETPQGLAGGWEYNSDLFDLATIERIAHHFHNLLIAV
                     TTNPEQPVGLLPLLTASEEQKILVDFNHTEADYPTDLYLHQLFEAQVERTPDAVAVGIG
                     TGEELTYAELNTRANQLACYLQFLGVGNEKVVGICVERSLDMIVGLLATLKAGGAYVPL
                     DPKYPAERLAFMVEDAEIEVLLTQQPLVDLLPKTMAKIICLDTEWLAISAYSPHSPQPT
                     THSPNHLAYIIYTSGSTGKPKGVQIIHSAVVNFLTSVAQEPGITAADVVLSVTTLSFDI
                     AVLDIFLPLMVGAKVVLVSTEMTKDGYALQKLLLESHATIMQATPATWRILLASGWNGT
                     EKLKILCAGEALPRDLANQLLARSCELWNAYGPTETTTWSTVYQVEPGEGKVLIGHPLG
                     NTQIYLLDTYGQPVPIGVAGELHIGGAGLARGYRNRPELTAEKFISSPFQEEKCLYKTG
                     DLARYLPDGNIEYLGRIDNQVKLRGFRIELGEIEAGIIAHPQVKQAVVIIREDQPGRKL
                     LVAYVVSQQETPTSSELRNLLQEQLPEYMIPNVFVFLEALPLTPNSKIDRRALPAPELE
                     ASNQDDVVKPRNHIEESLANIWGEILGLQQVGIHDNFFELGGDSIISIQVIARANQAGI
                     QLTLKQIFQHQTIAQLAAVCTMGSIPAEQGLVTGELPLTPIQHWFFAQNSPQPDHFNQS
                     VLLEVQPDLQPELLQQVVQKLLEHHDALRLKFWRDDSQWQQINSDAVNTVPFDVIDLSE
                     LSPKQQQETITALAAKLQASLNVSAGELMRVVLFKLETDKPSQLLIIIHHLAVDGVSWR
                     ILLEDFSTAYQQLSRGETIQLPPKTNSFKDWATHLQEYGQSPALKSEIAYWLTQSHNLP
                     LPVDYPNGKAHNTVASATQVSVSLSEEETLALLQEIPQVYNTQINDILLTACLQSFNNW
                     TGNNSLLIDLEGHGREELFADINISRTVGWFTSIFPILLSLDTTPFLRDSASLGETNQN
                     PGEALKSIKEQLRSLPQKGIGYGILRYLSDDEQMRQLASKAEVCFNYLGQFDRIPPGII
                     QGFAKTSTGATQSSLSHRPHLLEINGIVAEGKLHINLTYSEKVHKQSTIEHLANDFITA
                     LQTLIHHCQSATGGYTPSDFPAAELNQDELDALLAEIDE"
     CDS_motif       46532..46555
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0001"
                     /evalue="2.90E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="puwG"
                     /protein_end="70"
                     /protein_start="62"
                     /score="1.8"
                     /tool="antismash"
                     /translation="YGITETTV"
     CDS_motif       46670..46759
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0002"
                     /evalue="1.70E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="puwG"
                     /protein_end="138"
                     /protein_start="108"
                     /score="52.2"
                     /tool="antismash"
                     /translation="PVGVRGEMYVGGAGVTRGYLNRPELTQERF"
     CDS_motif       46874..46939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0003"
                     /evalue="1.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwG"
                     /protein_end="198"
                     /protein_start="176"
                     /score="39.8"
                     /tool="antismash"
                     /translation="YLGRIDDQVKIRGFRIELGEIE"
     CDS_motif       47150..47176
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0004"
                     /evalue="1.70E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="puwG"
                     /protein_end="277"
                     /protein_start="268"
                     /score="2.4"
                     /tool="antismash"
                     /translation="GKLDRRMLP"
     aSDomain        47237..47434
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_PCP.1"
                     /evalue="1.70E-25"
                     /label="puwG_PCP.1"
                     /locus_tag="puwG"
                     /protein_end="363"
                     /protein_start="297"
                     /score="81.0"
                     /tool="antismash"
                     /translation="ELLASIWTEVLGVSQVGIHDNFFELGGDSIRSIQILAQANQVGLD
                     FSLQQLFQYQTIAELAELVSK"
     CDS_motif       47297..47326
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0005"
                     /evalue="1.60E-01"
                     /label="PCP_mE"
                     /locus_tag="puwG"
                     /protein_end="327"
                     /protein_start="317"
                     /score="5.4"
                     /tool="antismash"
                     /translation="NFFELGGDSI"
     aSDomain        47519..48427
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="6.30E-64"
                     /label="puwG_Condensation_DCL.1"
                     /locus_tag="puwG"
                     /protein_end="694"
                     /protein_start="391"
                     /score="207.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHAILDG"
                     /tool="antismash"
                     /translation="EDAYPLTALQAGMVFHSELSADSAIYHDVFSFHLRATLDLPALHT
                     AIEQLMARYAVLRTSFELSGFSEPLQLVHQNVDVPLQVDDISDLTMAEQQAAIDAWIET
                     EKYRHFDWTQPPLWRFDVHRRSGETFNLSFSFHHAILDGWSVASLLTELWQQYLNLLKP
                     NPIPNPQSPVPTLAFRDFVALERTALQSETTQQYWLEQLRDVTITELPRWPQSYLEEAE
                     EEVSIQEVAISAELSDGLKQLARNASVPLKSVLLAAHLRVLNLLGNQADVLTGLVANGR
                     PEDADGEKILGLFLNTLPLRSH"
     aSModule        47519..50641
                     /complete
                     /domains="nrpspksdomains_puwG_Condensation_DCL.1"
                     /domains="nrpspksdomains_puwG_AMP-binding.1"
                     /domains="nrpspksdomains_puwG_PCP.2"
                     /locus_tags="puwG"
                     /monomer_pairings="Asn -> Asn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       47528..47569
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0006"
                     /evalue="7.40E-03"
                     /label="C1_DCL_004-017"
                     /locus_tag="puwG"
                     /protein_end="408"
                     /protein_start="394"
                     /score="9.1"
                     /tool="antismash"
                     /translation="YPLTALQAGMVFHS"
     CDS_motif       47588..47701
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0007"
                     /evalue="3.70E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwG"
                     /protein_end="452"
                     /protein_start="414"
                     /score="32.2"
                     /tool="antismash"
                     /translation="AIYHDVFSFHLRATLDLPALHTAIEQLMARYAVLRTSF"
     CDS_motif       47924..47989
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0008"
                     /evalue="2.20E-07"
                     /label="C3_DCL_135-156"
                     /locus_tag="puwG"
                     /protein_end="548"
                     /protein_start="526"
                     /score="23.4"
                     /tool="antismash"
                     /translation="FHHAILDGWSVASLLTELWQQY"
     CDS_motif       48329..48421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0009"
                     /evalue="9.70E-08"
                     /label="C5_DCL_263-294"
                     /locus_tag="puwG"
                     /protein_end="692"
                     /protein_start="661"
                     /score="24.5"
                     /tool="antismash"
                     /translation="DVLTGLVANGRPEDADGEKILGLFLNTLPLR"
     CDS_motif       48482..48568
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0010"
                     /evalue="2.40E-04"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="puwG"
                     /protein_end="741"
                     /protein_start="712"
                     /score="13.7"
                     /tool="antismash"
                     /translation="AALPHRRYPLAEMQRLCGGEQLFETSFNF"
     aSDomain        48914..50116
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_AMP-binding.1"
                     /evalue="3.60E-111"
                     /label="puwG_AMP-binding.1"
                     /locus_tag="puwG"
                     /protein_end="1257"
                     /protein_start="856"
                     /score="363.6"
                     /specificity="substrate consensus: Asn"
                     /tool="antismash"
                     /translation="FAAQVQKNTNAIAVTYEQQHLTYAQLNQRANQLAHHLQTLGVKPD
                     TLVGICVERSLEMVVGLLGILKAGGAFVPLDPAYPRDRLQYLLEDSQVPVLLTQSHLLD
                     ILPEHQQVICLDTDWQAISQQSQANPVSQVKSTNLAYIIYTSGSTGKPKGTMIIHQGVV
                     NYLSWCTEAYAVADGYGAPVQSSFAFDATITSLFSPLMVGKQVVLLPERQEIEALCSVL
                     RSKTQFSLVKLTPAHLELLNQIIPPAAAAGQTNAFVIGGEALLGKTLQFWRENAPETRL
                     INEYGPTETVVGCCIYEVTDDTSLTEGILIGRPIANTQLYILDEYLQPVPIGVRGELYI
                     GGAGVARGYLNRPELTKEKFISHPFIHEPGARLYKTGDLARYQPDGNIEYLGRTDHQVK
                     VR"
     CDS_motif       49100..49141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0011"
                     /evalue="3.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwG"
                     /protein_end="932"
                     /protein_start="918"
                     /score="17.1"
                     /tool="antismash"
                     /translation="LGILKAGGAFVPLD"
     CDS_motif       49331..49390
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0012"
                     /evalue="3.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="puwG"
                     /protein_end="1015"
                     /protein_start="995"
                     /score="28.9"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGTMIIH"
     CDS_motif       49763..49789
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0013"
                     /evalue="5.60E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="puwG"
                     /protein_end="1148"
                     /protein_start="1139"
                     /score="3.8"
                     /tool="antismash"
                     /translation="EYGPTETVV"
     CDS_motif       49904..49993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0014"
                     /evalue="3.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="puwG"
                     /protein_end="1216"
                     /protein_start="1186"
                     /score="57.7"
                     /tool="antismash"
                     /translation="PIGVRGELYIGGAGVARGYLNRPELTKEKF"
     CDS_motif       50081..50146
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0015"
                     /evalue="4.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwG"
                     /protein_end="1267"
                     /protein_start="1245"
                     /score="37.8"
                     /tool="antismash"
                     /translation="YLGRTDHQVKVRGFRIELGEIE"
     CDS_motif       50357..50383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0016"
                     /evalue="8.00E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="puwG"
                     /protein_end="1346"
                     /protein_start="1337"
                     /score="3.3"
                     /tool="antismash"
                     /translation="GKLDRNALP"
     aSDomain        50441..50641
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_PCP.2"
                     /evalue="1.10E-23"
                     /label="puwG_PCP.2"
                     /locus_tag="puwG"
                     /protein_end="1432"
                     /protein_start="1365"
                     /score="75.2"
                     /tool="antismash"
                     /translation="VLIADLFASLLGIKQVSIHDNFFALGGHSLLATQVISRLRVIFRI
                     EVPLRLLFESPTVAELDQAIHK"
     CDS_motif       50501..50530
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0017"
                     /evalue="1.50E+01"
                     /label="PCP_mE"
                     /locus_tag="puwG"
                     /protein_end="1395"
                     /protein_start="1385"
                     /score="0.2"
                     /tool="antismash"
                     /translation="NFFALGGHSL"
     aSDomain        50702..51598
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.10E-123"
                     /label="puwG_Condensation_LCL.1"
                     /locus_tag="puwG"
                     /protein_end="1751"
                     /protein_start="1452"
                     /score="401.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVCDG"
                     /tool="antismash"
                     /translation="QPIPLSWSQQRLWFLAQLESSSGTYNVPAALQLQGYLNVAALEQA
                     LQEIVHRHEVLRTSFPTINGVPTQVIVPAVTVTLPLIDLQGLPEQAEQVKQLTITNSQT
                     TFDLAIAPLMRSQLLRLGEQSHILLINLHHIVCDGWSVGVFIQELSALYTAFTEEKPSP
                     LPELAIQYADFAVWQRQWLSGEVLEKKLNYWQQQLAGAPPLLELPIDRPRPPIQSYQGG
                     YYGFTLDADLTAKLKSLSQKSSVTLFMTLQAAFVTLLHRYSGQTDILVGTPIANRDRKE
                     TESLIGFFVNTLVLRTQI"
     aSModule        50702..55252
                     /complete
                     /domains="nrpspksdomains_puwG_Condensation_LCL.1"
                     /domains="nrpspksdomains_puwG_AMP-binding.2"
                     /domains="nrpspksdomains_puwG_PCP.3"
                     /domains="nrpspksdomains_puwG_Epimerization.1"
                     /domains="nrpspksdomains_puwG_TIGR01720.1"
                     /locus_tags="puwG"
                     /monomer_pairings="Ala -> D-Ala"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       50771..50884
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0018"
                     /evalue="1.20E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwG"
                     /protein_end="1513"
                     /protein_start="1475"
                     /score="56.2"
                     /tool="antismash"
                     /translation="TYNVPAALQLQGYLNVAALEQALQEIVHRHEVLRTSFP"
     CDS_motif       51095..51160
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0019"
                     /evalue="1.70E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwG"
                     /protein_end="1605"
                     /protein_start="1583"
                     /score="39.6"
                     /tool="antismash"
                     /translation="LHHIVCDGWSVGVFIQELSALY"
     CDS_motif       51209..51247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0020"
                     /evalue="3.60E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="puwG"
                     /protein_end="1634"
                     /protein_start="1621"
                     /score="19.4"
                     /tool="antismash"
                     /translation="QYADFAVWQRQWL"
     CDS_motif       51500..51589
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0021"
                     /evalue="1.40E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwG"
                     /protein_end="1748"
                     /protein_start="1718"
                     /score="56.0"
                     /tool="antismash"
                     /translation="DILVGTPIANRDRKETESLIGFFVNTLVLR"
     CDS_motif       51638..51757
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0022"
                     /evalue="1.20E-25"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwG"
                     /protein_end="1804"
                     /protein_start="1764"
                     /score="82.1"
                     /tool="antismash"
                     /translation="RRVSLEAYAYQDVPFEQVVEALQPERNLSHSPLFQVMFIW"
     aSDomain        52094..53278
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_AMP-binding.2"
                     /evalue="1.10E-114"
                     /label="puwG_AMP-binding.2"
                     /locus_tag="puwG"
                     /protein_end="2311"
                     /protein_start="1916"
                     /score="375.2"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FEAQVERTPDAVAVGIGTGEELTYAELNTRANQLACYLQFLGVGN
                     EKVVGICVERSLDMIVGLLATLKAGGAYVPLDPKYPAERLAFMVEDAEIEVLLTQQPLV
                     DLLPKTMAKIICLDTEWLAISAYSPHSPQPTTHSPNHLAYIIYTSGSTGKPKGVQIIHS
                     AVVNFLTSVAQEPGITAADVVLSVTTLSFDIAVLDIFLPLMVGAKVVLVSTEMTKDGYA
                     LQKLLLESHATIMQATPATWRILLASGWNGTEKLKILCAGEALPRDLANQLLARSCELW
                     NAYGPTETTTWSTVYQVEPGEGKVLIGHPLGNTQIYLLDTYGQPVPIGVAGELHIGGAG
                     LARGYRNRPELTAEKFISSPFQEEKCLYKTGDLARYLPDGNIEYLGRIDNQVKLR"
     CDS_motif       52283..52324
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0023"
                     /evalue="3.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwG"
                     /protein_end="1993"
                     /protein_start="1979"
                     /score="17.1"
                     /tool="antismash"
                     /translation="LATLKAGGAYVPLD"
     CDS_motif       52520..52579
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0024"
                     /evalue="3.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="puwG"
                     /protein_end="2078"
                     /protein_start="2058"
                     /score="28.7"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVQIIH"
     CDS_motif       52943..52966
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0025"
                     /evalue="2.40E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="puwG"
                     /protein_end="2207"
                     /protein_start="2199"
                     /score="4.8"
                     /tool="antismash"
                     /translation="YGPTETTT"
     CDS_motif       53072..53161
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0026"
                     /evalue="9.80E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="puwG"
                     /protein_end="2272"
                     /protein_start="2242"
                     /score="56.2"
                     /tool="antismash"
                     /translation="PIGVAGELHIGGAGLARGYRNRPELTAEKF"
     CDS_motif       53243..53308
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0027"
                     /evalue="6.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwG"
                     /protein_end="2321"
                     /protein_start="2299"
                     /score="37.3"
                     /tool="antismash"
                     /translation="YLGRIDNQVKLRGFRIELGEIE"
     CDS_motif       53522..53545
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0028"
                     /evalue="1.40E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="puwG"
                     /protein_end="2400"
                     /protein_start="2392"
                     /score="2.6"
                     /tool="antismash"
                     /translation="KIDRRALP"
     aSDomain        53603..53797
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_PCP.3"
                     /evalue="1.40E-25"
                     /label="puwG_PCP.3"
                     /locus_tag="puwG"
                     /protein_end="2484"
                     /protein_start="2419"
                     /score="81.3"
                     /tool="antismash"
                     /translation="EESLANIWGEILGLQQVGIHDNFFELGGDSIISIQVIARANQAGI
                     QLTLKQIFQHQTIAQLAAVC"
     CDS_motif       53666..53695
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0029"
                     /evalue="1.60E-01"
                     /label="PCP_mE"
                     /locus_tag="puwG"
                     /protein_end="2450"
                     /protein_start="2440"
                     /score="5.4"
                     /tool="antismash"
                     /translation="NFFELGGDSI"
     aSDomain        53834..54745
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_Epimerization.1"
                     /evalue="1.30E-161"
                     /label="puwG_Epimerization.1"
                     /locus_tag="puwG"
                     /protein_end="2800"
                     /protein_start="2496"
                     /score="531.0"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLAVDG"
                     /tool="antismash"
                     /translation="TGELPLTPIQHWFFAQNSPQPDHFNQSVLLEVQPDLQPELLQQVV
                     QKLLEHHDALRLKFWRDDSQWQQINSDAVNTVPFDVIDLSELSPKQQQETITALAAKLQ
                     ASLNVSAGELMRVVLFKLETDKPSQLLIIIHHLAVDGVSWRILLEDFSTAYQQLSRGET
                     IQLPPKTNSFKDWATHLQEYGQSPALKSEIAYWLTQSHNLPLPVDYPNGKAHNTVASAT
                     QVSVSLSEEETLALLQEIPQVYNTQINDILLTACLQSFNNWTGNNSLLIDLEGHGREEL
                     FADINISRTVGWFTSIFPILLSL"
     CDS_motif       53849..53878
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0030"
                     /evalue="5.90E-04"
                     /label="NRPS-E1"
                     /locus_tag="puwG"
                     /protein_end="2511"
                     /protein_start="2501"
                     /score="12.8"
                     /tool="antismash"
                     /translation="LTPIQHWFFA"
     CDS_motif       53903..54001
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0031"
                     /evalue="1.90E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwG"
                     /protein_end="2552"
                     /protein_start="2519"
                     /score="17.0"
                     /tool="antismash"
                     /translation="FNQSVLLEVQPDLQPELLQQVVQKLLEHHDALR"
     CDS_motif       54221..54286
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0032"
                     /evalue="3.60E-11"
                     /label="NRPS-E2"
                     /locus_tag="puwG"
                     /protein_end="2647"
                     /protein_start="2625"
                     /score="35.2"
                     /tool="antismash"
                     /translation="LLIIIHHLAVDGVSWRILLEDF"
     CDS_motif       54689..54739
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0033"
                     /evalue="1.30E-07"
                     /label="NRPS-E5"
                     /locus_tag="puwG"
                     /protein_end="2798"
                     /protein_start="2781"
                     /score="23.7"
                     /tool="antismash"
                     /translation="NISRTVGWFTSIFPILL"
     aSDomain        54803..55252
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_TIGR01720.1"
                     /evalue="6.00E-47"
                     /label="puwG_TIGR01720.1"
                     /locus_tag="puwG"
                     /protein_end="2969"
                     /protein_start="2819"
                     /score="151.3"
                     /tool="antismash"
                     /translation="GEALKSIKEQLRSLPQKGIGYGILRYLSDDEQMRQLASKAEVCFN
                     YLGQFDRIPPGIIQGFAKTSTGATQSSLSHRPHLLEINGIVAEGKLHINLTYSEKVHKQ
                     STIEHLANDFITALQTLIHHCQSATGGYTPSDFPAAELNQDELDAL"
     CDS_motif       54821..54883
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0034"
                     /evalue="1.50E-10"
                     /label="NRPS-E6"
                     /locus_tag="puwG"
                     /protein_end="2846"
                     /protein_start="2825"
                     /score="33.2"
                     /tool="antismash"
                     /translation="IKEQLRSLPQKGIGYGILRYL"
     aSDomain        55202..55264
                     /aSDomain="NRPS-COM_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_NRPS-COM_Cterm.1"
                     /evalue="1.50E-09"
                     /label="puwG_NRPS-COM_Cterm.1"
                     /locus_tag="puwG"
                     /protein_end="2973"
                     /protein_start="2952"
                     /score="29.4"
                     /tool="antismash"
                     /translation="PSDFPAAELNQDELDALLAEI"
     gene            55344..58709
                     /gene="puwH"
     CDS             55344..58709
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (7-36). E-value: 3.4e-19.
                     Score: 59.8. Matches aSDomain:
                     nrpspksdomains_puwH_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (14-311). E-value:
                     6e-120. Score: 391.8. Matches aSDomain:
                     nrpspksdomains_puwH_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-890). E-value:
                     9.8e-123. Score: 401.7. Matches aSDomain:
                     nrpspksdomains_puwH_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1017-1083). E-value: 5.9e-26.
                     Score: 82.5. Matches aSDomain: nrpspksdomains_puwH_PCP.1"
                     /codon_start=1
                     /gene="puwH"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /note="NRPS; non-ribosomal peptide synthetase"
                     /product="PuwH"
                     /protein_id="AXN93616.1"
                     /sec_met_domain="Condensation (E-value: 1e-82, bitscore:
                     267.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3e-129, bitscore:
                     420.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.5e-18, bitscore:
                     55.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTISEQPAKSKNVAAIYPLSPMQQGMLFHTLYSPESGIYFEQFIC
                     TISGNLNVAVFKQAWQQVVERHPVLRTLFVWENRKKPLQIVRHQVTLPWTECDWRLLAP
                     SEQQKQVEEFLVSDRTQGFKLDQAPLMRCALLRLGENTYELVASFHHLLVDGWSLPILF
                     QEVFTFYEAGNRGERLSLATPRPYQEYITWLQRQDIAAAENFWRQNLQGFTAPTPLGGN
                     RGVHHQGNFLDITFELSSQITDTLQSFAQQHRVTLSTLVQGAWSILLSRYSGELDVVFG
                     ATVSGRPPTLVGVESMVGLFINTLPVRVQIPEDTAIVPWLQYLQTQQIEREPYSYSPLV
                     DIHGWSEIPRGMSLFESLVVFENYPVDAALQEPLASLEIDHVRVFEINNYPLTLVVAAQ
                     QTLSGKIIYDSDRFDADTVTRMMGHFQNLLTAIVTQPELPITQVPLISNTEKQQLISAW
                     DAHKTEYSSNYCLHQLFEQQVEKTPDAVALVFGEQSLTYSELNVRANQLAHHLQSLGVK
                     PETLVGVCVERSFEMMVALLGILKAGGAYLPLDPDYPAERLEFMLADAQVSVLVTQSQC
                     LDILPIFSANKVCLDTDWQVISTLSSENPVSQAIPESLAYVIYTSGSTGKPKGVMVNHG
                     NVTRLFAATQDWFKFDARDVWTLFHSYAFDFSVWEMWGALLYGGRLVIVPFWVSRDPEA
                     FYDLLLREGVTVLNQTPSAFRQLIWVENSRRDAEAQRGGNERIALRWVIFGGEALDPTS
                     LLPWFERHGDACPQLVNMYGITETTVHVTFRPLSMADAGSRSSVIGVPIPDLQVYILDE
                     HLQPVPVGVRGEMYVGGAGVARGYLHRPELTQERFIRLGIRNNPVTYNPLYKTGDLARY
                     LPDGNIEYLGRIDHQVKVRGFRIELGEIEAALNQHPVVQENVVIAREDTPGNQRLVAYI
                     VADAVKSESPQIPSTTKETTWTSPQLLINELRQHLEGQLPDYMIPWAFVLLDSLPLTTN
                     GKLDRRALPSPDLDQNRHTSFVSPQTETEQAIADIISSVLEITKIGIHDNFFELGGHSL
                     LATQVVSRLRQTFTIELPVQTIFQSPTIAGLAEIVIGKQLEQVDDDALAQILAEVNQLS
                     SQEVKLQLNKDESI"
     aSDomain        55365..55451
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwH_NRPS-COM_Nterm.1"
                     /evalue="3.40E-19"
                     /label="puwH_NRPS-COM_Nterm.1"
                     /locus_tag="puwH"
                     /protein_end="36"
                     /protein_start="7"
                     /score="59.8"
                     /tool="antismash"
                     /translation="AKSKNVAAIYPLSPMQQGMLFHTLYSPES"
     aSDomain        55386..56276
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwH_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="6.00E-120"
                     /label="puwH_Condensation_DCL.1"
                     /locus_tag="puwH"
                     /protein_end="311"
                     /protein_start="14"
                     /score="391.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLVDG"
                     /tool="antismash"
                     /translation="AIYPLSPMQQGMLFHTLYSPESGIYFEQFICTISGNLNVAVFKQA
                     WQQVVERHPVLRTLFVWENRKKPLQIVRHQVTLPWTECDWRLLAPSEQQKQVEEFLVSD
                     RTQGFKLDQAPLMRCALLRLGENTYELVASFHHLLVDGWSLPILFQEVFTFYEAGNRGE
                     RLSLATPRPYQEYITWLQRQDIAAAENFWRQNLQGFTAPTPLGGNRGVHHQGNFLDITF
                     ELSSQITDTLQSFAQQHRVTLSTLVQGAWSILLSRYSGELDVVFGATVSGRPPTLVGVE
                     SMVGLFINTLPVRVQI"
     aSModule        55386..58592
                     /complete
                     /domains="nrpspksdomains_puwH_Condensation_DCL.1"
                     /domains="nrpspksdomains_puwH_AMP-binding.1"
                     /domains="nrpspksdomains_puwH_PCP.1"
                     /locus_tags="puwH"
                     /monomer_pairings="Thr -> Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       55392..55430
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0001"
                     /evalue="8.20E-06"
                     /label="C1_dual_004-017"
                     /locus_tag="puwH"
                     /protein_end="29"
                     /protein_start="16"
                     /score="18.3"
                     /tool="antismash"
                     /translation="YPLSPMQQGMLFH"
     CDS_motif       55455..55571
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0002"
                     /evalue="1.40E-20"
                     /label="C2_DCL_024-062"
                     /locus_tag="puwH"
                     /protein_end="76"
                     /protein_start="37"
                     /score="65.6"
                     /tool="antismash"
                     /translation="IYFEQFICTISGNLNVAVFKQAWQQVVERHPVLRTLFVW"
     CDS_motif       55788..55853
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0003"
                     /evalue="1.70E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="puwH"
                     /protein_end="170"
                     /protein_start="148"
                     /score="36.5"
                     /tool="antismash"
                     /translation="FHHLLVDGWSLPILFQEVFTFY"
     CDS_motif       55899..55937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0004"
                     /evalue="1.60E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="puwH"
                     /protein_end="198"
                     /protein_start="185"
                     /score="11.1"
                     /tool="antismash"
                     /translation="PYQEYITWLQRQD"
     CDS_motif       56172..56267
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0005"
                     /evalue="2.60E-20"
                     /label="C5_DCL_263-294"
                     /locus_tag="puwH"
                     /protein_end="308"
                     /protein_start="276"
                     /score="64.8"
                     /tool="antismash"
                     /translation="DVVFGATVSGRPPTLVGVESMVGLFINTLPVR"
     CDS_motif       56316..56438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0006"
                     /evalue="7.60E-23"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="puwH"
                     /protein_end="365"
                     /protein_start="324"
                     /score="73.1"
                     /tool="antismash"
                     /translation="QTQQIEREPYSYSPLVDIHGWSEIPRGMSLFESLVVFENYP"
     aSDomain        56766..58013
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwH_AMP-binding.1"
                     /evalue="9.80E-123"
                     /label="puwH_AMP-binding.1"
                     /locus_tag="puwH"
                     /protein_end="890"
                     /protein_start="474"
                     /score="401.7"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEQQVEKTPDAVALVFGEQSLTYSELNVRANQLAHHLQSLGVKPE
                     TLVGVCVERSFEMMVALLGILKAGGAYLPLDPDYPAERLEFMLADAQVSVLVTQSQCLD
                     ILPIFSANKVCLDTDWQVISTLSSENPVSQAIPESLAYVIYTSGSTGKPKGVMVNHGNV
                     TRLFAATQDWFKFDARDVWTLFHSYAFDFSVWEMWGALLYGGRLVIVPFWVSRDPEAFY
                     DLLLREGVTVLNQTPSAFRQLIWVENSRRDAEAQRGGNERIALRWVIFGGEALDPTSLL
                     PWFERHGDACPQLVNMYGITETTVHVTFRPLSMADAGSRSSVIGVPIPDLQVYILDEHL
                     QPVPVGVRGEMYVGGAGVARGYLHRPELTQERFIRLGIRNNPVTYNPLYKTGDLARYLP
                     DGNIEYLGRIDHQVKVR"
     CDS_motif       56952..56993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0007"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwH"
                     /protein_end="550"
                     /protein_start="536"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPLD"
     CDS_motif       57186..57245
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0008"
                     /evalue="2.40E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="puwH"
                     /protein_end="634"
                     /protein_start="614"
                     /score="35.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVMVNH"
     CDS_motif       57795..57884
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0009"
                     /evalue="4.80E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="puwH"
                     /protein_end="847"
                     /protein_start="817"
                     /score="54.0"
                     /tool="antismash"
                     /translation="PVGVRGEMYVGGAGVARGYLHRPELTQERF"
     CDS_motif       57978..58043
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0010"
                     /evalue="1.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwH"
                     /protein_end="900"
                     /protein_start="878"
                     /score="39.9"
                     /tool="antismash"
                     /translation="YLGRIDHQVKVRGFRIELGEIE"
     aSDomain        58395..58592
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwH_PCP.1"
                     /evalue="5.90E-26"
                     /label="puwH_PCP.1"
                     /locus_tag="puwH"
                     /protein_end="1083"
                     /protein_start="1017"
                     /score="82.5"
                     /tool="antismash"
                     /translation="EQAIADIISSVLEITKIGIHDNFFELGGHSLLATQVVSRLRQTFT
                     IELPVQTIFQSPTIAGLAEIV"
     gene            58970..60901
                     /gene="orf1"
     CDS             58970..60901
                     /codon_start=1
                     /gene="orf1"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /note="ABC transporter"
                     /product="ORF1"
                     /protein_id="AXN93617.1"
                     /transl_table=11
                     /translation="MNLFSREFWKQFLAIAKPYWYPRATEDRKFIKVLSSWLLLALAIG
                     LVIATNAINVYNSFVTRDLIDLLEERDIPAFFRLLFIYANLLIILIPLVGILQYLKKKI
                     ALDWYQFLNNHILDKYFQNRAYYRVNFRTEIENPDQRIAQEIEQIPQIATQIFFVVVEK
                     TLEIVSFLAVIWSIYRPVAVIIVIYGILGNIVAGYLSQRLIKISTAQLEGVADYSYSLT
                     HVRNNAESVAFFQGEEQEADIVKRRFAKLMDAKKQMIGWLRDQQVFVTSYQSFLSILPF
                     LGIAPLYFFNQIELGEVSQASTACSIFAGALSVLVTEFGGSGKFVNLVERLSTFSAILE
                     VTKAKKTGKKIETLEANRLELQNLTLQTPNYERVIVKDLSVVVESGKGLLIVGASGRGK
                     SSLLRAIAGLWEAGTGRIIRPKLEEILFLPQRPYLILGTLREQLLYPNQNRQMKDEELE
                     QVLQQVNLSDLTSRVGGFDANVYWENILSLGEQQRLAFARLLVIRPRYVILDEATSALD
                     LKNEEKLYQQLQQSGTTFISVGHRESLFNYHQLVLELSEESNWRLVPIEEYSINREFIQ
                     LSETEPIKVLEIVPDKLQSEDSKLTALKIDGLRKLCKEKGIKWRNARGTGKHLTKGEML
                     AMLNEIVV"
ORIGIN
        1 ctacttacaa tcgaaaatag caccacgaat gcaggcttgt aaatgttcag ctagtacctg
       61 aacatgaggt ggttgcatca tggttaaatg agtaccggga acaatatgga tatctactgg
      121 ttcatctgaa aaattattcc aacccaaggt taaatcttgg aggcgattaa cgtattctgc
      181 gatcgcctgt tcttcttcat gaacttcact agcacggaat aaagtaatag gagtgttgtt
      241 taccaacgac gggaagtaat tactaaaggc ttgcgtatgg gttttgtaca cttgcacaaa
      301 gcctctgagt tgaattttac tagcatcagt cggcaaaatt tgcgcaattt tcaactgttc
      361 cagtaggtaa tctaactgag tttctgcact caagggctgt aaagtttcgt agtcaagttg
      421 cagggttgta ttaaacaacc gttccatgac tttggctact tgcatcaacc acatcgcatc
      481 atctaattct attttccgcg atcgctcaga acgaactggt gcgatagtat cgagaattgc
      541 taacagtcca atttcgtgtc cttgctgttg tagctgctgc gccatttcaa acgctactaa
      601 gccgccaaag gaatgaccac ctaataaata aggcccttgg ggttggacgg tttgaatagc
      661 tttgatgtac tcagttgcaa tctcttcaat gcggtgtaat ggttctgatt ccccgtctaa
      721 accttgggct tgcaaaccgt agaatggttg ttctgcaccc aaacaacggg ctaaatcata
      781 gaaatacagc acatttccgc ctgcgccggg gatgcagaag aaagggggat tgatgccgtt
      841 ggtttgaatg ggaactaagc ttgaccataa agaagcatct gttgactgac gcagcagatt
      901 ggctaattct tcaatggttg ggttttggaa gagggaggct aggggtaatt gtttatgcag
      961 cttttgttga atttgcgcca tcaaacgcac tgctaacagg gaatgtccgc caatttcaaa
     1021 gaagttatcg cggattccta cccatttaac gcctaaaacc tcagaccaaa tttgtgtaag
     1081 ttgcaattct aaagagtcgc ggggggctac agctaactgt gatggattga ttccattggg
     1141 tgaaggtagc gatcgcctat caactttacc actaggcgtt aaaggtaaag catccaaggc
     1201 cacaaacact gatggcatca tatattcagg taactgttgc tgtagaaaat gacgcaactc
     1261 tgaaggtgtg gcttgttgtt ccgagttgaa gacaacataa gctatgaggc gtttttcagt
     1321 ggaagtttcc ccttggacaa ccacaatcgc ctgtttcacg tggggatgat gattcaacgc
     1381 cgcttcaact tcacctaatt caatgcggaa gccgcgcacc ttcacttgat tgtcaagacg
     1441 accaagatat tcaatattac catcaggtaa aaaacgcgct aaatcccctg ttttatataa
     1501 tttagcctga ttatgagtaa tgaatttctc agcagtcaac tctggacggt tcaaataacc
     1561 tctagctaca cccacaccac cgatatataa ctcaccccta actcccatcg gtactggttg
     1621 tagatattta tctaaaatgt aggtttgagt attagcgatc gcctgaccaa tcggcggtaa
     1681 catcggccac tcttccacat catcacttag agtaaacgcc gtcaccacat gagtttctga
     1741 agggccatac tggttatgta gtgtacaatt tcccaaacgt tgtagaaaat tctttaaagc
     1801 gggtgtcact tgtaactgtt ccccggctgt gatgatttcc cgtaaaggtg gcaaagattc
     1861 cacattagct gagacttccg ctaattgctg caaagctaca aaaggcaaga ataacctttc
     1921 tacaccttcc tctgagagta aattgaataa cgcaatagta tctttgcgtg tgtcttctgg
     1981 taataaaacc aatgttcccc cagcacacca agttgcaaaa atttcttggc aggacacatc
     2041 aaaactcacc ggcgcaaatt gtagagtttt agcgttagcg gctatggaag tatgattaat
     2101 ttgccactgg aggaggttaa ctaaagcact atggggcata gctacaccct tgggtttacc
     2161 agtagaacca gaggtataaa ttacataagc taagttgtcc gaagttagtc cactgacagg
     2221 gatgtgtgag ggcagattat cccaggagac agcatctaaa caaactacct gcgctgtgtg
     2281 tgttgggaat atttctacta agtttgatgt tgttagtaat acagccgctt gggaatcttg
     2341 tagcatataa gccaagcgat cgcctggata agtcgagtcg agaggaacat aagcaccgcc
     2401 agctttgaga atcgccaaca aacccacaac taaatctagg gaacgttcaa tacaaatacc
     2461 cactgcgact tctggctgca cacccaaagt ctgtaagtaa tgcgccaact gatttgcacg
     2521 agtatctaac tcagcgtaag ttagttgttt ttccccaaac accacagcta tatgatcagg
     2581 tgtaagctgt acctgagttg ccaataattc tgggatagat tcctctatgg cgtaagttgt
     2641 cccatcccct aataattgtt gctgttccgc ctcagtcagc aacggtaact gagcaattct
     2701 ttcctctgga tgagcgacaa tccccgccag cagggtttgg aaatgggcaa tcatgcggct
     2761 gatcgtctct ggctcaaata agtcgctgtt atattcccac caacccgcaa gcccttgttt
     2821 tgtctcccaa attgacaagg ttaaatcaaa cttggcggtg acattttcac tcgccaatgg
     2881 gacaaaactc aagccaggta attctaaatt acccatcggc gcattctgta aaatgaacat
     2941 cacctgaaac aaaggtgcat gactcagttt gcgttccggc tgcaaagctt ctactatttg
     3001 ctcaaagggt acatcctgat gagcatagcc atctaaggct acttgtttta cctgattcaa
     3061 taattctgag aacttgggat tatctgcaac tttatttctc agcaccaaag tattgacaaa
     3121 aaagccaatt aatggttcta attctttgcg gttgcggttg gcgatgggag taccgacgag
     3181 aatatcatcc tgaccagtgt agcggtgcag caacgtcaca aacgccgctt gcaaggtcat
     3241 aaataaggta gcccctgctt gttggctaag gaggttgagt tgttcgctga agtcttttct
     3301 caattggaaa gccaagcgat cgcctctaaa agtctgcaca gccggccggg gtttatcggt
     3361 gggtagttct aatacagggg gtgcatctgc tagttgttgc tgccaataat tcagcttagt
     3421 ttctaatact tccccagtta accattgtct ctgccacact gcaaagtcgg catactggat
     3481 gctcaaatct ggtaatgggg aaagtttacc cgcagctaag gccggataca tcgccgagag
     3541 ttcttgaatg attaccccca ttgaccaacc atcagcgaca atatgatgca gagtgaaaag
     3601 caacacatgg gaatttgcat ctaattgtaa tagtgtcgcc ctgactaaag gtgcttggtt
     3661 gaggtcgaat ggtttttggg cttcttcgtt gctgaatttt tctacggctg cttgttgttg
     3721 gttgtttgat agttcccgca ggtcgataat ttctaaactt aaactagcat cagtgttaat
     3781 tacctggaca ggattaccat cgattaaatg aaaactggtt cttaaaattt cgtgacgctg
     3841 gacaatatcg gagagtgttt gtttgagtgc gtttacttgc aattccccag taatttgcaa
     3901 aacgttgggc atattgtaag tggaactcgc cccttctaat tggtagagaa accacaatcg
     3961 ctgctgcgcc catgacattg gtaggggttc gcctgttctg ggtatgggtg ttatagcagt
     4021 tgcggttaat cctgttccac cttgacgcag attactaata aattgatcca gttccacaac
     4081 gctgggtgct tcaaataaac accgcagggg taactctacg ggaaatgctt cctgtaggcg
     4141 agaaattacc tgagttgcta acagggaatg tccccccaac tcaaagaagt tatcataaac
     4201 gccgatttct tctagtccca acacctcagc aataattgca gcgatgattt cttcctctgc
     4261 ggtacgggga ggaacaaaac tcacagtccg actcagttct agattgggta caggtaacgc
     4321 cacccggtca actttaccat taggagttaa aggtaagacg ggtaataaca tgaaagcgtt
     4381 aggtatcatg tagcctggaa gtttatcttt cagaaaactc cgcagttgtg ggattaactt
     4441 acgcgctagt tgtccctgta gtaagttatt gccgtaatta ctccaaggtt caattgtctg
     4501 tgaatgctca aaaatcggga gaacattctg attaccttta acaaacacca catcataatt
     4561 acccttctct gtctgtgacc aactgatgtg tacctgtaat gataattctt tttcccaacg
     4621 ccaaaactct tccggatcaa tcaacgagtc cccagtcccc aatcccctct gtagttcgcc
     4681 gactgttgcg ttttcgggaa gacttgctaa taaatctagc agtctcatct ctgtttttaa
     4741 ccgcgcattg gggatgtttt tcacacctaa aatctctaca tctgctttgg ttagcaagtc
     4801 ttgcagcaaa ggtaatgtta actgatcttg ctgccaatcc aaccattgcg gaacaacttt
     4861 tggtgtgact gcattaccta gatgtaaggt gacatcataa cgaaactggg tcagttcatt
     4921 atgatattca ccgcgtttga tttgaatctg cacatgacta atttggggga agcgttgctg
     4981 tagtgcagtg aaaaaagcgg ggtcaattac aagttctgag tcttggttaa gattgcgttg
     5041 gatgcgttgc tgtaaatctc ctgtagagag agatgggaga gattgcgcca actgcaccga
     5101 ggcgtggaaa gcttctagta agggtaaact gcggacatcg cctataaaaa taaaccctgc
     5161 cgatgcgatc gcctgcatgg cattttctag cacttgcatc agataatcaa tgctagggaa
     5221 atactggact acggaattaa gaacaaccgc atcaaaaccc ccttgttcga ctccatgaaa
     5281 attctcggcg gaacgttgcg ccaatttaac ttgtgaccaa tccctcccca tctgggtaat
     5341 ttgctgctgt acataccgca aagcctgggg cgaaatatca gtcccatagt aacaatcaca
     5401 ctggggcgca atcctaaata gcagcatccc tgtaccacaa ccaatctcta acacctgttt
     5461 tggttgccag tcaagaatcc tatctactgt agattccacc cattcccgca tttcagcttt
     5521 ggggataagt aacccagtac ggctatcgtt ccagccaata atattgaagg tgggatctga
     5581 gtcggttgca gattgactgt aactatcgtt aaatacttgt tgccattggg aaagttgttc
     5641 tgattcaaat tcattagcta gactggagtc agtgcgatcg ctatcttggg aattaggcac
     5701 aacataagca actaaacgct tatctccagg gatatcttct ctagtaatga caactgtttc
     5761 ccgcacttcg ggatgttgat tgacagctgt ctcaatttct cccaactcaa tccgaaagcc
     5821 tcgtagtttc acctggtgat ctgtccgtcc gaggtattca atattgccat ctggttgata
     5881 acgcgccaaa tctcccgtct tatacagccg tgcgcctggt tcatgaataa agggatgcga
     5941 aatgaatttc tcttttgtca actcaggacg attcaaatag ccccgcgcca caccagcccc
     6001 accaatatat agttcacctc tgacaccaat ggggactggt tgcaggtatt catccaaaat
     6061 ataaagttgg gtattagcaa tgggacgacc aattaaaata ccctctgtta acgaagtgtc
     6121 atctgtcact tcataaatac aacaacccac aacagtttct gtcgggccat attcattaat
     6181 tagtcgagtt tgcggggcgt tttctcgcca aaattgcaaa gtcttaccta agagggcttc
     6241 accaccgatg acaaaagcgt tggtttgtcc ggcggcttct gctgggggaa taatttgatt
     6301 gagtagttcc aaatgagcag gcgtaagttt cactaaacta aactgactct tagactgcaa
     6361 aacgctacac aaagcctcaa tctcctgctt ttccggtaac agcaccactt gcctacccac
     6421 cattaaaggt gaaaacaagc tagtaatagt tgcatcaaaa gcaaaagaag actgtacagg
     6481 tgcgccgtat ccatcggcta cagcataagc ttcaatacac caactgagat aattcactac
     6541 ccctcggtga attatcattg tccccttggg tttgccagtt gaaccggagg tataaattat
     6601 ataagctaag ttagtagatt ttacctggga aacgggattg gcttgactct gttgggaaat
     6661 cgcttgccaa tctgtatcca gacaaatcac ctgctgatgc tctggtagaa tgtttagtaa
     6721 gtgcgactgg gtaagtaata caggcacttg agaatcttcc agtaagtatt gtaggcgatc
     6781 gcgtggataa gctgggtcaa gaggtacaaa agccccgcca gctttcaaaa tccccaacaa
     6841 acccaccacc atttctaaag aacgttctgc acaaatcccc actaatacct cagcctccac
     6901 tcccaagctt tgcaaataat gcgccacctg attagcacga gcattcaact caccataagt
     6961 taactcttcc ccattcccca aaactgctac agcatccggt gttagttcta cctgagcctc
     7021 aaacatctga tgcaaacata acttcgtcgg atactctttt tgagtatcgt tccattcgac
     7081 aagtaactgt tgctgttctg cttgtgtcag tatcggtaaa taggcaatct gctgatgagg
     7141 attagccacc actgctgcta acaaagtctg caaatgttcc gctatccgga tgattgtaga
     7201 ctcatcgaat aagtcgcggt tatattccca aacacccccc agtccctcgt ctgtctctac
     7261 gaatgtgaga gttaagtcac gcttggctgt ggcaaaatta atatcgatgg atgtcaactc
     7321 caaatccaat agtttcagtg tgccttgagg tgcattctgc aacaccaaca tcacctgaaa
     7381 cagtggatta tgatctaagt tgcgttctgg ttgtagggct tccactacct gctcaaaggg
     7441 tacatcctga tgttcgtagg cttctagggc tacttgttgt acttgtttga gtagttcgct
     7501 aaatttggga ttaccattaa gcttggttcg caacaccaaa gtattgacaa aaaagccaat
     7561 taatgattct atgtcttgac ggttgcgatt agcgatgggc gtaccgacga ggatatcatc
     7621 ctgactagta taacgatgta gtaatgtgac gaatgccgcc tgtagagtca taaacagagt
     7681 tacccctgac ttttgactta ggctcaaaat ttgctgtgtt agctggctgc tgagtgtaaa
     7741 tgtatagcta cctccccgaa aagtctctat cggtgggcgt ggtctatctg ttggtaattc
     7801 caataaaggt ggcgcacctg ctaacttttg tcgccaatag ttgagtttag tttctagcac
     7861 ttccccactt aaccattgtc tttgccacac agcaaaatca gcatattgaa taggtaactc
     7921 tgctagtggg gaaggtttag ccgtggcaaa ggcgggatag agggcggata gttcttgaat
     7981 aaagatcccc attgaccaac catcaacaac aatatgatgc acagtcaata gcaatacatg
     8041 ggaagtttca tccaagcgta gaatttgacc gcgaattaag ggcggttgtt ggaggttaaa
     8101 aggtttgtgt gcttcttggt ggactaattg ttgaacttga gaggctttct ctatatctga
     8161 taaatcttgc aagtccacca ctggtaaatt taccatcaca gtaggatgaa caacttgccg
     8221 gggagtatta ttaatttctt gaaaggttgt tcttaaaact tcgtgacggc gaacaatttc
     8281 gattatggct tgctctaagg cattaatatt taacttccca gtaatttgta aagcagttgg
     8341 tgtattatat gtcgcactga ggccaactag ttggtcgaga aaccagagtc tttgttgagc
     8401 aaatgataaa ggaattgctt ggtttctatc tacaggaaca agtggtaagc tttgagattt
     8461 attattatct gttgcagaat tcgtcttctg catttgcagt ttttttaaaa ctaattcacg
     8521 ctgttctggt gataaataat caagcctttt taataaatcg ctcataaatt ttaaaaattg
     8581 tttgtagtga ggactttagt ccttttctta ctgtgaaatt aaaacgcaga cttgaatcta
     8641 gtagtctatc aagttagttt tgagggttcg tagtattcgc atagcgtctg tctacgacac
     8701 gctccgcgaa cgtagagagg actaaagtcc ttactacgaa attgcttatg cctcaattca
     8761 catttgatga cctactagta gtggcttgac caggctaaaa tagtccatta gacgtagctt
     8821 gggttaagcg cagcgcaaca ttgtcttagt gttgggtttc cttacgtcaa acgccactcg
     8881 tcccaagccg ggaaacccgt ccaaggcggt ggcttcccaa cctactacca attattctta
     8941 actaaaccgt attgtactag caattgactt ttaattcact aatttattgc acaattcatc
     9001 tatttcttct gttctctctg caatcatttg cttggctact tgaatcagca tccgaatatt
     9061 gttaaacttc gcattatcca ttgcttctaa gctttcatct aagtatgctt gtaagcggta
     9121 atactgttgt tgggatttat cttcagattg ggggatgagt tcttctattt gactagaaat
     9181 agcttgattt acaccgtcta aaacaatatt taacattggt ctagcccagc ctaataatcc
     9241 ccaatttttc gcttcttggt aagggtatgg tttggtgagt gaacctgttc ccaaagaaac
     9301 tactaacgta ttatcaagag tccaaggttc ttcacctttc ttgatagctt ctttagcacc
     9361 aataatagat tctattacgg ctaacccagt gggattatta gcgaaaactc ccccatctac
     9421 taatgtatag aaaccatttt cgttatgtga tgtaggaatg cgatatgggg caaaatatgt
     9481 tggagcagca ctagttgcca ttgctgcttc tttcatggta aagccctcac ctatcttgcg
     9541 caattttcta gatgtattat tttctttgtt aagattactg ctaaacaaaa ctggtactcg
     9601 ctgttcaata tcatagctag gaatgagaat ttctgtaata gcttccacta ttgttgtaga
     9661 gccaaaatat tgggtgagga tgtcgtttct tccctcggat gtatattttg gtttgagaat
     9721 ttcgtcgaat tctcctaata gttctgcgta tagtggctca taaaatatta cattaccatg
     9781 ctcggcaaag atattaacta agtctttagc agtgtatgaa ggtttttttg tggcatttaa
     9841 ttgaggttta gttaacccta gggcgatgat tcctcccgtt gaagttcccg caatgagatc
     9901 aaacaaactg gcgattggtt tttgagtgcg tgtttcaatt tcttcgagaa tcatcgctgg
     9961 gataattccc cgaataccac caccatcaat tgacaaaatc ttgtatggat acttgcttgt
    10021 tttatttttt gtgctttcct gtttagtttt agtggcttta ggcgtttctg gaatgataac
    10081 ttgtgtttgt tctagcatag atgtaggtgg ttgagttgtt tttggtataa cttcttgaga
    10141 ttctgattgg ggtggtgttg gctgttggtt ttctctagaa atttccgttt tcaccccaac
    10201 agttttatca ataatattgc cgtggttggc gtgattagtt ttatcttgta ttattattgt
    10261 tcccggtgca tcgcttagtg gccagtagcc tactaatccc ggttcattcc caacaagaat
    10321 atgagtcata tcagcttgaa tttctgcttc agaacgagcc ttgttccaga tgcgaacttc
    10381 tgcaattttt ccttgaaacg gataagattc gttattatct tggtaaattc caattactaa
    10441 gtcattttcg ggattgtaat caatgttgct atcagctgtg gctttagtgg ctttttctac
    10501 accatcaacg tatactctca tgcgtttacc gtcataagtg ccggcgatgt gatgccagtg
    10561 atttagttgg atggaatttt ccttactact aagatattga atgcctttgg atggagtttt
    10621 taaggcgaag aatatcccac ttttaccatc taagagtaga ccatatccac tttcaatttg
    10681 accagtgtca aaaacgttcg tgataattcc ggttcttctt ctttgcgctt gacaattaat
    10741 ccaagcttct aaggtgattt gctgtgcaat tttaaattcg gcttttttac ctaaatcgat
    10801 ataaatatct ttgccatcaa acaccaaacc tgatggagta aactggtttg gctgtagtgc
    10861 tactgctgct tctgactggt tttgttcgtt atctttaacc attatttcag gtgctaaatc
    10921 ctttttagct tgcttctgtt gtggggagac ggaagaattg actgtacaac tcttctatgg
    10981 catcaaaata gttgttaact tatctagtac agtacggctt aaatcaagct acgatttcca
    11041 acaagtaaaa gcctcgatat acgagacttt tgactttcgt ataggggtac tagtatgtaa
    11101 tatgagcgat cgccttttct ataagtctct atatatttcc ctatttgcca tctgacggtt
    11161 tgactctcat cattgagtct gccgacacga tgcgataggc gatcgcatcc ttaatgagcc
    11221 tctagaccat ttactctgtt aaggcatgaa ttaatgaaag gtttgtagtg agtgtctcta
    11281 acctttttat gtgtccgcta tggtaacaga gtagggttaa agccctcact acgaaccatg
    11341 cttagaattg catcagaaaa ttatgcagat agtgactatt gaatttccgc aacttgggaa
    11401 ccaacaacta ctaaatcggc ttccgttttg ggtggattag aaatattatc tttgagttta
    11461 attttcagtt catcggaaat aggcaaactg ttaatttctc tcaaaatacc tcccagtgct
    11521 tcatttttgc tgcgttctgt gtaaacagca ctcagcactt tttcaatccc ataccctgct
    11581 aaggattcag ttaccagagt cacaattcct aaaactgcca agcctcccat catcccaaat
    11641 gggccaccaa gggtagccag aaccatagga acaacaacat taccttctag acctgttgtt
    11701 gcaattacga ttaccagcat tgcaccaggt aaccccagcg atgccagctt tttcaccact
    11761 tcatccatac aaatcaccta aagatttaat taaaggacta tgttcgctcg attctgtttt
    11821 ctgactaaac ctgcgatcgc acttggttaa gtattaaacc agtcatttgc aggttaaccc
    11881 caagtctact gagatagatt gtaacttcaa gaatttttaa tgcgacgcta ttacctaagc
    11941 tatattaagg ttttacgaac taggtgatga tcgcaatact agtatacttg gtttgatctc
    12001 aaaactactg tatcattcct caagatattt cttcacaatc atttacatac gtcctatgtc
    12061 accccctata gtagaattaa acacgttaca tttctattac ttagggctaa gtgcctcaaa
    12121 gctttaaatt ttttgtccca ttgaggccac aggggagcag ggagcaaggg tgagggtttg
    12181 cagctttgat gaccatgaaa atggtgcaat ttaaatgatg attagcttat taccatttct
    12241 tatacagcgt tttgctatca aagatgtttt gaaaatggtg tatgacttct ttcaagtccg
    12301 cgtatttcat aaatattttt ttaaatattg actttttact cttttaatag tatggatcac
    12361 acaattcaag ctgaaagttt tattgataat ttagataaag tcgccggagt tcgtcaagaa
    12421 atttctgtat gtttagcgca gatgggtgac atccttagtc aagcggaatt agctggaaaa
    12481 aagacttcgg gcgcactagg tttgagttca gatattgaaa acatcaattt agccagtcaa
    12541 aatctgcatc aaggtatatt tcgcttactc gttttaggcg atatgaagcg agggaaaagc
    12601 acttttatta atgccttaat tggggaaaat atcctgccga atgcagttaa tccctgtact
    12661 gctcttttga cgattttgcg ttatggagaa gagaaaaagg taactgttca ttttaatgat
    12721 caaaaaactc cagaacagct tgaatttaaa gaatttaagc agaagtacac gattgatcca
    12781 aaagaagcta aacagctagg caaaggcaaa aaaatggtat ttgctgaagt cagtcatgcc
    12841 attgtagaat acccattacc gcttttatcc aaagggctag aaattatcga tagcccagga
    12901 ctaaacgaca ccgaagacag aaatgaaaca tcattaggat acatcaataa ttgtcatgca
    12961 attctgtttt tgatgagggc atctcagcct tacactttag ccgagcgacg ctacctagaa
    13021 aattatatta aaggtcgtgg tttgacggta ttttttatta ttaatggttg ggatcaaatt
    13081 caagaaggca ttctagatcc agatgacgaa gaagaattgc aaacagcaga gatgcaattg
    13141 cgagaattat ttgaggtgaa tttagcacaa tactgtcaaa ttaacggaaa agatatttat
    13201 tctgagcgcg tctttgagat ttctgccatt aatgccctga gaagaagaat taagaatcaa
    13261 tcagcctcct tagaaggtac aggatttcca gaattgctgc gatcgctcaa tacattttta
    13321 acccaagatc gagcgatcgc tcaactacaa ccagcgatta tcctggctca ccaaacctac
    13381 actaacatcc aagctgctat tcaacgccgc ctttccttac tcaagcaaga tgtgagtgaa
    13441 atgaaacagc gcattagttc cgtagaacca gaatttgagc agttaggcat aattcgtgat
    13501 caatttcagc aagaaattat caccacaaga gatattcaag ccaagactat tgcggaatct
    13561 ttgcggtctt acattctcaa tttgggtaat acctttgaaa ctgatttttt accctaccaa
    13621 ccagacttag aactattcga ttttttaaac aaagataaac gtgaagcctt taatgagttg
    13681 ctacaacaag ctttcgagca atacacagcc gataaaattg cgacttggac gttgacagta
    13741 gaacaagaca tgaatgcagc ctttgccaaa ctttccacca gtgcagcaac ctatggtgct
    13801 tcatacagcc aagttacaga ccaaatcgcc aataaattat cgggacaaga actaaaacgt
    13861 aaaccccaaa atactaccgc agaagattca cctacttgga caaaatgggc gatgggatta
    13921 ttatctttgt ctaggggtaa cattgctggc gtggcgatgg cacaagcagg ctttgactgg
    13981 aaaaatattt tactcaatta catcgcagca attggtgtga acagtgttac cagcagcatc
    14041 actggtattt ttttagggcc tgtggggttg gcgtttttag gtatgggtat tggctttgtc
    14101 caagccgacc aagctaggca aaaattagtc cagacgactc aaaaagaact aacgaaatat
    14161 ctcccacagg cggctgaaga atatcttccc caaatccgta caggggtaga agaatgcttc
    14221 aacacctacg aacgggaagt gattgagcaa atcaacaaag atattactca aagaagagca
    14281 gaattagata acttgctcca gcaaaaagca gcacatgaaa ttaacctgca aactgaatct
    14341 cagcgtctcc aatcagtagc cgcagaagtt taccaacagc tacagcaggt tgacaaagtt
    14401 tatagtgttg ttaacaccga aacagcgaag agtgctgatt agtgttagtc ggtaggagat
    14461 ggtaagtagc attggtcaaa tttccatgcc ttatcatccc ctaggcttca ctgcctttat
    14521 atacgaagaa tctttgcagt aaaatgtaat acctgtactg attatatcaa tttatagcgg
    14581 tacacagtat ataaaagagt tactgatttt atctctctga atataaagtg atttgctcaa
    14641 atctcttgat ttaaagaaag tttaatgctc ttttaataat ctgtacaggg gttgtatgcc
    14701 aatatatttg tgtcaatttt gactgagaaa aaaaagtatt ttattaaaat caagctatta
    14761 agcgtttaat ttgtgctatt tttatggtat taaagatact atgtgggctt aaataaagtt
    14821 ttacgaagta tcaaatagga ctcctgtttg attgctagac aagactcaga gtctatatat
    14881 cccttctttc cagttcccta ttaagagtta cctgttttct gccgacgcaa gtaaattcag
    14941 gaatcaaacc gaatttctgt atacactttc gtttgtgcgt gtaaaaaatt gaaatcaatt
    15001 attttgcaag aaactacaac gctagtagac ctcctgcaac ttagagcttt gcagcatccg
    15061 cacaaagcag cttttacgtt tttgcaggat ggcgaaacag cagcctacag cttgacctat
    15121 caagcattag aacaaaaggc tcgctcaatc gctgctaagt tacaaactct cgtaaccaga
    15181 ggtgacaatg cttcgcccgc cataggtgtt cgcgctctgt tactttatcc accagggtta
    15241 gaatttatca gtgccttttt tggttgtttg tatgcccaag tagtagctgt tccagcatat
    15301 ccgccgcgac gtaaccagaa tctagcaaga ctccaggcga tcgtggcaga tacgcaggca
    15361 acagtagtcc tcaccaccac cgcgttacta tccaaccggg aagcgtggtt gaaccaagca
    15421 ccagaactag cccaagtaca atggctagcc actgatgaca ttgacgtgaa cttggcagcc
    15481 gattggcaac aacctcgaat cagtagtgat accctagcct ttctccaata cacatctggt
    15541 tctactggca agccaaaagg ggtaatggtt agtcatgaaa atgtgctgta caaccaacgc
    15601 atgattcagc ttgcctacca acacacccag gaaactatct ttgtgggttg gttgccctta
    15661 ttccacgaca tgggactgat tggaaacgta ttacagccat tatatttggg gatatcatgc
    15721 tatctgatgt ctccagtggc ttttctccag aaacctattc gttggttgca agccatttca
    15781 cgttatcaag ctactaccag tggtggccca aactttgctt atgacttgtg tgtgagcaaa
    15841 attacccccg aacagatagc tagccttgac ctcagcagtt gggaattggc ctttaacggt
    15901 gcagaaccag tacaagcgga aaccctagaa aaatttgctg ccaagtttaa atcttgcggc
    15961 tttcgtgctg aagcttttta tccctgctat ggcatggctg agactacctt gttcgtttct
    16021 ggagggatga aaacatctgc acctgtagtg ttatctgttg atgaagcagc cattgaagag
    16081 aatcgagttg tagtaactag tggagaacaa ccgcagggca aacaaatagt cagttgtgga
    16141 cagacttggt tagagcagaa aattgcgatc gccaacccag aaactctgac ccagtgtagc
    16201 ccagaagaag tcggagaaat ctgggtatca ggtgcaaacg tcgcggctgg ttactggcaa
    16261 aattcagaag caaccaaaga gacatttcaa gcgtatttag ctgacactgg agagggtgaa
    16321 tttctccgca ccggagactt aggatttatc cgcgacggcg agttattcgt cacaggtcgc
    16381 atcaaagact taatcattat tcgcggacaa aaccactatc cccaagacat cgaactcacc
    16441 acccaaaaga gccattcagc cttacgtctt ggttgtggtg cagccttttc tattaccgtt
    16501 gcaggtgaag aaaggttagt cattactcaa gaagtcgaac ggagttattt acgccagtta
    16561 gatgtagatg aagtagtcgg agcaatccgc caagcagtat cacaacaaca tgaactccaa
    16621 gtttatgcag tcgtcttact caaaacagcc agtattccga aaacctccag tgggaagatt
    16681 caacgtcaag cctgtaggac tgggttttta gccagaaacc tagatattgt cggagagtgg
    16741 caagtcaact tccaagaact ggaattagca gcactgcaaa cctctctagc aaccttattg
    16801 gaacacgtcc aacaaggcgc acaaaatcat tctgcaagtg aacaaactgc cttgaattct
    16861 gaaaagattc aaaactggtt agtcacacat ttagctttat ctctaaaact gccgccagat
    16921 gagatagaca ctcaagagtc ttttgctcat tatggtttag attcatcagt ggcagttagc
    16981 atgacgagtg aattaggtga gtggctaggg tgggaactag accccaccct attttgggaa
    17041 tttcccagta ttgccgcatt ggctcaacac ctagatgcag aatgtcgatt attaaaatca
    17101 acgaatcaag tcaagctttc agggaaaatt taacaatgga gtcaattgct gagagcagcc
    17161 aagagatgat taactctggg cagaaccaac cagcaaggac agttaaacct tttaggttta
    17221 atcccctact tgctaatttg catcaagatc catatcccac ctaccatcac ctgcgtgaga
    17281 aagatcctgt acatcagaac ttattaaatg cttgggtact tacccgctat gaagatgtca
    17341 gaacagtttt gcgcgatccc cgcttttgtg tagataaatt agccacccgc gtaagaaata
    17401 aaagcaatta cctcacccag caaaaggatc tggatacatt agctgatgtt actggtaaat
    17461 ggttaatcta cctcgatcca cctgaccata ctagactccg caaacttgtt ggtaaagcct
    17521 tttctccatc agtcatcgat cctctgcgtc cctacattca aggaattgtg gatcagttac
    17581 ttgacaaagt gcaacaccag ggaaacatgg aagtgattgc cgatttagct gctcccttac
    17641 ccgtcaaagt gattgccaaa atgttgggtg tacctgatca ggattgcccc cagctacatc
    17701 agtggtctaa tgacctatct cggatattag atccgctttt accactacaa acctatgaac
    17761 atttaaatca gatagttctg gaatttgcag aatacttccg tgcaatattt gcagaacgcc
    17821 gaaaaagccc acaagaagat ttaatcagcg cactaattga ggctagagac caaggcgaca
    17881 aattgagcga agtagaaatg ttgtctacct gtatattatt gtttattgct ggggaagaaa
    17941 ctacagtcaa tacaatcggt aatgggattc tggctttact ccgtcaccct gaacagctag
    18001 aaaaactgag acaagaacct actataattc aaagtgctgt tgaagaaata ctacgttacg
    18061 acagtcctgt acaatatgcc caaaggattg ctacagaaga tgtagagatt ggtggcaaac
    18121 tgattaaagt aggtgataaa gttgtcgcct gtctaggtgc tgctaaccga gatccggcac
    18181 aatttattga tccagatcgc ctcgatctta cccgtagcga taaccgccac atggctttta
    18241 tcgatggcac acacacttgt ttgggaggag cattagctcg cctcaatagt caaattgcta
    18301 ttaatacatt tgcacaaaga ttttcccata tagaactaca aaccgatcaa ttagattggc
    18361 gtaaaaatat tgctttgcga ggattaaagt ccttatcagt aagttttaaa agtaattaga
    18421 aattctcaat tcataattaa aaattttaga ggaacaaaat ggacaaagaa cccatcgcca
    18481 ttattggaat aggatgtcgt tttcctgggg ctaaaaaccc ggaagccttt tggcatttgc
    18541 tgcgcgatgg gatagatgcc attaccgaag tgccgaagac acgctgggat atagatgatt
    18601 tttatgatgc tgacccagcg acaccagata aaatgactac gcgatggggt ggttttttag
    18661 agcaaataga tcaatttgac cctcaatttt tcaatattgc ccctagagaa gccgccagtg
    18721 tagatcctca acatcggttg ttactagaga ccacctggga agccttagaa gatgctggac
    18781 aaaatcctac agccttagcg ggtaaacctg cgggcgtgtt tatggggatt tctagcttcg
    18841 actacgataa gctacgcttc caaaatcccg ttaacttaga tagctatgca ggtacaggta
    18901 cagctttatc cttggctgct aaccggattt cctatgcttt aaatttcaca ggcccaagta
    18961 ttgctattga tactgcttgc tcctcatctc tggtagcagt tcatctagct tgccaaagct
    19021 tgcggaatgg ggaatctacc ttagctttag ctgggggtgt gaatgtgatg gcttcccctt
    19081 gggtgacagt caccttttct aaaggtggct tcatggccac tgatggtaga tgtaaagctt
    19141 ttgatagtcg ggctaatggc tatgttcgca gtgaaggggc tggggttgta gtattaaaac
    19201 tactatctca agctgaggca gatggcgatc gcatttatgc cattattcgt ggtagtgcag
    19261 ttaatcaaga tggtcgcagt aacggtatca ccgcacccaa ttctttagcg caagaagccg
    19321 tactcagaga agcctaccgt caggcgggag tatctcctgg taaggtgcag tatatagaag
    19381 cccacggtac aggcacaaaa ttaggcgacc ccatagaagt caaagccttg gggaaggtac
    19441 tcaatgaagg tcgcattcct ggagaatatt gtgctttagg ttcagtcaaa actaacattg
    19501 gtcacgccga agccgccgcc ggtattgctg gattaattaa agttgcactc tccctaaaac
    19561 atgggcaaat cccggcgagt ctgcatttcc aagaagccaa tccttatatt ccctttgata
    19621 aattacccct acgagtccag caaaaactag aatcttggcc agaaattgga gaaactacta
    19681 tagctggggt gagttccttc ggttttggtg ggactaatgc tcatgttgtc ttgggaaggc
    19741 agggagcagg gagcaggggg cagggagcag ggagcaggag gcagaaagat gtcttttctc
    19801 ctacaccctt acacccttac acccctatac ccctacactt gctgacttta tcggctaaga
    19861 gtgaaaaagc actgcaagaa ctagtgcaga gttatcagga ctatctcaag aatcatcctc
    19921 aagtatcatt gacggatgtt tgttttacag ctaacgttgg acgcaaccat ttcgattatc
    19981 ggttaggaat tgcttctaac tctacaatca aactacaaga gcaattagcc gcatttttat
    20041 taaaacaaga cactcccgga gtcttccagg gacaaatcaa tagtcgcaaa catcctaaag
    20101 tagtcttttt atttacaggt caaggttcgc agtatgtcga tatggggcgg aaactctacg
    20161 aaacccaccc cacattccgc caaatcctcg atgactgcaa ccaaatcctc ctaccctacc
    20221 tagaaacacc cctcctagaa atcctttatc cccagttacc agtcctcagt ccccagtccc
    20281 caatcaacga aactgcctat acccaacccg ccctcttcgc cttagaatat gccctagcta
    20341 aactctggca atcttggggg atagaagcct cggcagtcat gggtcatagc gttggggaat
    20401 atgtcgccgc ttgtctggcg ggggtgttca gcttagaaga tggcttaaaa ctcatcgctg
    20461 aacggggtag gttaatgcag gcattaccct caaatggaac aatggcagcg attatggcag
    20521 atgaacagac agtgttatct gctattcaac cctacggtga gcaaatcgcc atagcagcct
    20581 ataacggcgc agaaagtctc gtcatctctg gacaacgcca agctatagaa gccgtttgtc
    20641 agcaactgac aaatcaaggt atccaaacca agcctctaca ggtttcccac cctttccatt
    20701 ctcccttgat ggaggcgatg ctgggggatt tcgagcaggt agccaagaca gtacaatact
    20761 cgtctcctaa aattccccta atttccaacc tgacaggaca aattgcgaca acagacatcg
    20821 ccacacctga gtattgggtg catcatatcc gccaaccggt gcaatttgcc tccagtatga
    20881 agttgctgca ccagcaaggt tatcagatat ttgtagaaat tggcgcgaaa cccacattaa
    20941 ttggcatggg tcgccaatgt ttacctgatg gtgtaggggt ttggttgccg agtttgcatc
    21001 ccaagcaagg cgaatgggag caaattttag caagtttggc ggcgttgtat gtccggggtg
    21061 ttcccatcaa ctggggcgaa ttttatcgac attctgactg tgagccagtt tctttaccta
    21121 cctatccttt ccaacgacaa cgctattgga tagagacagt atcacctctg catcagccaa
    21181 gtttcaattt agttcagggt caacagcacc ccttacttgg tcaaaggctg aatttagcag
    21241 gtgtgaagga aatttgtttc cagtccgaga ttagccaaaa tcaacccgct tatctgccag
    21301 atcatcgcgt ttttggtgag gtcattgtac cagctaccgc ttatctcgaa atggcattgg
    21361 ctgcgggatt taaaatatat aaatctgtac aattagtatt agaagatatt agtattttac
    21421 agccattgat tttgggagaa ataggcataa ccttacaaat tagcctatct ccaggtgatg
    21481 gtagttatcc attccgaatt tttagtagtg aaaatattac agatactgaa tcagtatgga
    21541 gactccacgc cacaggtaaa ttactgcggg gtgaaaatca agctgaaccg atccaaactg
    21601 acttaacaaa attgcgatcg ccatgttatg aaaatatagc acctctgaat tactatcagc
    21661 aatgtcaaaa tagaggtatt gattatggct ctagtttcca agctatccaa caactctggt
    21721 atgctccagg tttggcgatg ggacaggtgc agttagcaga aacttgggca gatcaaaatt
    21781 atcacctgca tccgattatt ttagatgcaa gcttccaagt attaggtgcg gctttactcc
    21841 atgaaaatca actagatacg tatttacccg tagaaattaa gcggttacag attcatagta
    21901 gtccgggaaa tctggtttgg agtcacgcag agattaaccc agacacaaat caagaactta
    21961 ttagtggcaa tgttagcctt tatacggagg atggagtaaa aatagttcat gtacagggtt
    22021 tagagttgaa gcggtcgcgc ctacttccca caacccaaga caattggcat aactggcttt
    22081 atcaagtggc gtggcggcaa aaagtccact ttgccagttc acaactcagc cctgattact
    22141 tggtatctcc tgagcaagta agtatgaaaa tttctgctaa attgcctgat atactgactg
    22201 attttaattg gtcagagtat cagcaagtct tcacccaaat ggaagcctta agcatcgcct
    22261 acatcattca tgcttttgca caaatgggga gaaaattcca acttgggcaa cgttttgcta
    22321 cagcagacat catcacccaa ctgggcatag tcaaccgcca tcacaggttg ctacatcggc
    22381 tattagagat tgtggcagat gcgggttact tacaggaaag taactcacaa tggcaggtaa
    22441 tacatatacc ccaggattcc aacccagaca ccaaattaaa tctcctgttg gcaaaatacc
    22501 ctagtgcagt tgccgagtta acattattgg ggcgttgtgc gagtaaactg gcatcagtcc
    22561 tgcaaggtga cagtgacccc ttgcaattgc tgtttcctga aggcgacatg accaccgcta
    22621 cccaagttta tcaggattct ccagggtcgc aggtactgaa tagtttagtg cagcaggcta
    22681 tttcctcagc tttagcacag ttacctcaag acagaggtgt gcggattctc gaaattgggg
    22741 cgggtacggg aggaactacc gcttacattc tgccaaccct accagcaaag caaacagaat
    22801 acatctttac tgatttatcc ccccgcttta ctactcaagc ccaagagaaa tttcgcgatt
    22861 atccctttgt acagtatcaa gtattagata ttgaacagga attaaagcca cagggattcg
    22921 agtttcacca atatgatgtc gtggtagcgg ctaacgtcct ccacgccacc caggatttag
    22981 cacaaacctt gcaaaatatc cgccagttat tagcaccgca agggttactt atactattag
    23041 agggaactat tccccaagct tggctagatt taacctttgg cttaactgaa ggttggtggc
    23101 gatttagtga tactgagtta cgtcccaatt atcccctgct aacgagtgaa caatggcagc
    23161 aagtcttatt gcaagaggga tatcaagcag ccgtcaccct acctttagcc gcagcaaccc
    23221 aaggtagttt aaatcagcaa tctgtaattg tggcacaagc cgcccccacg cagaaaactg
    23281 tagcggctgc tacgtccaaa cattggcttg tattggctga ctctcaagga cttggtgaaa
    23341 aattagcgac tcaattacga gaaaaaggtg atatttgcac cttagttttc tcaggcgagg
    23401 actataaatt actggatagg gaaactttga cgctcaatcc cactcagcca gagcattttc
    23461 agcaactact aactagaatt agcaatagtg aaactgcttt acatggtgtt attaattgct
    23521 ggagtttaga tacatctgat gctttaacga gtcttaacct gaagttaacg agtaaagatt
    23581 taaaagccgc atccagacaa agttgtggta gtaccttaca tctattgcaa gcattaacta
    23641 agacagattt tacctcacag cctcggttat ggttagtcac cagaggggcg caatctgtgg
    23701 agggtaatgt ttctggtgta acccaatctg cactctgggg aatgggtaag gtaattgctt
    23761 tagaacatcc agaacttaaa tgtgtgcggg tagatttaga ttctcatccg gttgaggatg
    23821 aagtcaacgc acttttagct gagattttag caagtgatga agaagatcaa gttgctttcc
    23881 gccatcagca gcgttatgtg gcgcggttaa ttaggacggg ggaaaatcag ctagaaattc
    23941 ctgaaaatca gccttttacc ttaactattt cccaaaaagg aactttagaa aatttaacct
    24001 ttgaaccgac tgtacgccgt tcacctgatg cgggggaagt agaaattaga gtcagggcga
    24061 cggggttaaa cttccgggat ttgctcaacg ctttagactt gtatcctggt gatgcgggga
    24121 cgttgggtgg tgagtgtgct ggtgaaattg tcgccgtggg tgcgggggta tcaggtttag
    24181 cggtgggtga tgctgtcgta gcgatcgcac ccgcaagttt cagtcaatat gtgacagtga
    24241 atgctcaaat ggtagcacca aagccagcca atttgacctt tgccgaagcc gcaactattc
    24301 ccattacctt cctgacagcg tattattcac tacatcattt aggaaaaatt gcccctggag
    24361 aacgggtatt aattcatgcg gcggctggtg gtgtgggaca agccgccatt cagttagccc
    24421 aacagatagg tgcagaagta ttcgctactg ctagtcctgg aaaatgggat ttcttgaaat
    24481 ctctgggagt cgaacaaatt atgaattccc gtagcttaga cttcgccgag caaataaaag
    24541 aaattactga aaaacaaggt gtaaatattg tcctcaattc cctaacctca gacgaattta
    24601 tcagcaaaag tttatctgtg ttacaacccc aagggcggtt tgtggaaatt gccaagcggg
    24661 gagtattaca gactgacgaa gtattaaaag tgcggtcaga tatcgcttac tttttagtgg
    24721 atttagtaga agtttgccaa cagcaaccca ccttaattca atcaatgctg gcgaaattaa
    24781 tgccgcaatt tgctacagga caactcaaac ccttacccca aacccaattt cctataacag
    24841 atgtagtaga tgctttccgc tatatgcagc aagccaagca tatcggtaag attgtcgtca
    24901 ctcaaacaga acttaccttc cgtgcagaca gcacctattt aattactggt gggatgggtg
    24961 gcttaggctt actcgtggct gagtggatgg tagagaaagg ggcgagacat ttagtattgc
    25021 tgggacgcag tggtgcaaat ggcgaggtga aacaatctat caaaacactg caacaaaagg
    25081 gcgcacaggt gatggtgaca caagcggatg tcgtcaacct agaacagatg accaaagtta
    25141 tagaagatat agagcgatcg cttcctccat tgcgcggtat tattcatgct gtcggggtat
    25201 tagatgatgg cgtactccaa caacaaacct gggaacgctt caccaaagtt atgtctccca
    25261 aagtagaagg tgcttggaac ttacatcaac ttacccaaca tctaccccta gatttcttcg
    25321 tcttattctc ctccgtcgcc tccctctttg gttcaccagg acaagccaac cacgccgccg
    25381 ctaacgcctt ccttgatacc tttgctcatt accgacaaca gcaaggactt ccaggcttga
    25441 gtattaactg gggtgtagta actgacattg gtgcagccgc caaacgccaa gcagattcct
    25501 gggtaaaagc taagggtatc ggtacgattg cgccacatca agtattagca gtattagaac
    25561 agcaaatgtt agcccccgca tctccccaag tcggggtagt tcccgttgat tggtcgaagt
    25621 ttaacatctc gccgttcttc caagatttgc aacctcaagc caaatccaca gaaccatcca
    25681 gccaagctgg ggaatttctc cagcaattgg atactatccc caaaggtgaa catcgtgctt
    25741 acttaatgaa tcatgtctgt agccaagtcg ccacagtttt gggtgggaat cccgcaacag
    25801 ccattgatat tcagcaaggc ttctttgatt taggtatgga ttccctcacc tctgtagagt
    25861 tgagaaaccg cttgcagaca agtttaggct gtagtttacc ttccaccctc acctttaaat
    25921 atccgacagt aacggcactg gtggattatt tagcaatgga agtgctgaat ttggcgacac
    25981 cgccaccaga gacaaacgta aaaaatcagg attgggaagc cgtcaaacaa ctctctgacg
    26041 atgaagttga tgcttccatc gccaaagaaa ttgccgaact agaagcatta ctgaggggga
    26101 aatcatgatt tctacagaaa ttaaacaatc actacagcta gaaaatcagt tctccacctt
    26161 agtagaactg ctgcaatatc gagccaaaat ccaacctgag aaaactgctt ttaccttcct
    26221 ccaggatgga gaaatagaga ctggtagttt aacttatcaa agtttagcgc aacaagcaaa
    26281 agcgatcgcc tctcaacttc atctgagagg gaaaataggt gatggcgttc cgcccatcat
    26341 aggtgatcgc gctctgttac tatatccccc agggttagaa tttattgccg ccttttttgg
    26401 ctgttcgtat gggggcgttg tggctgtacc cgcctatcca ccgcgacgta atcagaattt
    26461 atccagactt caggcaattg tcgccgatgc tcaagccacg gtgattctga ctaccaaatc
    26521 cctattacct caacttcaag agtggtttag tcagaatgca gaattagccg ctatcaaact
    26581 cctcgccact gatgacttaa acagtaactt agcggcaaac tggcaagcac cacaactgag
    26641 tcaagacagc ctagcctttt tgcaatacac ctctggttct acaggtaaac caaagggtgt
    26701 catggtgagt catggtaact tattacataa ttccgagtac ctcaagcaag cttttggact
    26761 ctcatctgag agcatttctg tttcttggtt gcccagtttt catgatatgg ggttaattga
    26821 aggaattttg caacccttgt acacagggtt tcttggggta ttaatgccgc ctgtctcctt
    26881 tgtccagcaa ccaattcgtt ggctgaaagc tattacccgc tatagaggta cacatggcgg
    26941 tagccccaac tttggctatg atctctgcac cagaaaaatc actcccgcac aaatacaaca
    27001 gcttgattta agtagttgga ataatgctta ctgtggtgct gaaccagtga gtaaagccac
    27061 cctagagaaa tttacggaaa ttttccaagc ttgtggtttc cgtagtaatg cctttgaccc
    27121 ttgttatgga ttagctgaag ctaccttaat ggtttctgga ggactagtag aagatgagcc
    27181 ggtgtattgt gcggtggaaa ctgaagcact agaaaacaac caggtggtga ttagtcaagg
    27241 agaacagcaa aacgttaagc aacttgtggg gtgtggacgt gcatggctag ataccaaaat
    27301 tgcgatcgca catccagaaa acttaactca gtgtaaaccc gatgaaattg gtgaaatctg
    27361 ggtatctggt gctactgtag cttgtggtta ttggcaacgc cctgaagaga caaagcaaac
    27421 ttttcacgcc tatctagcag atacaaaaca agggccattt ctgcggactg gcgacttagg
    27481 atttttgcgt gatggtgagt tattcgtcac cggacgcatc aaagacgtac taatcatccg
    27541 gggacggaat cattaccccc aagacattga actcacagta gaacaaagtc acccagcttt
    27601 aaggccaagt tgtggtgcag cttttacggt gacagtcaag ggagaagaga agctgattgt
    27661 tgttcaggaa gtagaaagaa gttggttgag aaagctagat ggagaagccg taattattgc
    27721 cattcgcaaa gccattgctc aacaacatga actgcaaatt tatgccacat tcttaattaa
    27781 aactaacact atcccgaaga catccagtgg caaaattcag cgtcgattat gtcgagaaaa
    27841 attacttaca ggcaaattgg aggtattagc ttcagacaat aaaaatctca taagttagta
    27901 gtcagggctt tagccctttc ttcgagaaaa tccgttaaca aaaaactaaa atccttagta
    27961 taaaaaataa agaaatgaca acagctaaca caaaaactat tccttccact gaacaaattc
    28021 aagattggct aatttcctat atggccgata tgctagagat tacaaccaat gaagttgata
    28081 tcagaatgct gtttgatgaa tatggtctag attcttctat gactataggg atgataggtg
    28141 atttagaaac ttggttgggc tgtaatttag atccaacatt agtttatgat tactcaacta
    28201 ttgaagattt agccaaacac ttaggctcta atttaatatc agataatttg ctctaacttt
    28261 ttattagtga gatacaggtg atgatttctg catctgttgc agcttaaagc agagattaag
    28321 acataccagg tagaagggtt attaggggta aattgtaatg agttccgaaa ccaccgagca
    28381 aatgactgca tcccaacgga tgttattagc actcaaagaa gcccgcgcca aactagaagc
    28441 ctttgaccgt gctaaaactg aacccatcgc tattattggc ataggttgta gatttccggg
    28501 gggagctaac aacccggaga cattttggca gttattgcgt gatggtgtag atgccattac
    28561 agaagtgcct agaagtcgtt ggaatatcga tgaatactac gaccccaacc cagagacacc
    28621 agggaaagtt tacacccgct atggcggatt tttagagaat gtagaccaat ttgaccccca
    28681 atttttcggc atttccccca gagaagctgt tagcatgaat ccccagcaac gccttttatt
    28741 agaggtagct tgggaagcgt tagaagaagc tgggattaat cctaaacaac tagttaatag
    28801 tttgacaggc gtttttttgg gtgtcggccc caatgactac gccaagttac ggatgaatgc
    28861 agacaaagcc gagaatatca ctgcccacga tggcacaggt aacggtttgt gctttgcttc
    28921 tggtcggttg tcttatgttt tggggttgca ggggccaaat ttagcaatgg atacctcctg
    28981 ctcatcttct ttggtggcag tgcatctagc tagccagagt ttacgggctg gagaatgtaa
    29041 cttagcgatc gcaggtggtg ttaacctaaa cttattcccc gaaactaccc tatttctctc
    29101 ccgcacccac gccttagccc ctgatggacg ctgcaaaacc ttcgatgcgg ccgccgatgg
    29161 ttttggcaga agcgaaggct gtggggtgat tatcctcaaa agattatctg atgctttggc
    29221 tgatggcgat tgcatttggg caactattcg cggttcggct gtcaaccacg acgggccaag
    29281 tagcggttta acagtaccca atcaactcgc ccaagagcaa ctaattcagc aagccctcga
    29341 taatgctaaa gtcaccccag cacaagtcac ctacatcgaa gcccacggga caggaacttc
    29401 cctcggcgac cccatcgaag ttggtgcatt agcatcagta ttttgtcgcc aacgttcccc
    29461 agaagaacca ttagttatag gttcagtcaa aaccaacctc ggtcacttag aagcagcagc
    29521 aggaattgcc ggactaatca aaacagtcct agcactacat cacggcgaaa ttccaccgca
    29581 cttgcacttc catcaaccca gtccccatat accttgggaa aacttgcctg ttattgtccc
    29641 tactcaacct acaccttggc aacccaaaga taaatcacgc atcgctgggg taagttcctt
    29701 tgggatgagt gggactaatg tgcatattgt tttagagagt cccgtagaga cgttgcacgc
    29761 aacctctgtc aatagtcaac agaaaaatga gtgtccagtg catctgttgg ctttgtccgc
    29821 taagactggg gaagcattaa aagaattagc aagaaattat acaaaatatt tacaaattca
    29881 cccacaaata tccttagctg atttgtgctt tacagctaat acaggacgca gccattttga
    29941 gcatcggtta gctgtggtaa ctgattctgt ggcaaagttg caaacacaac tgagtgcatt
    30001 tgctgagaat aacccagcag agggattatt acaccatcac cttacccaaa gaaaaacttc
    30061 taaaatagct tttctgttca caggtcaagg ttcacaatac ctcggcatgg gcaaacaact
    30121 ctacgacacc caaccagtat tccgcgaaac tttagaccac tgcgacaaaa ttttacagcc
    30181 gtatttagaa aaacccctat tagaaatcct ctatccccaa tctccagttc cccaatcccc
    30241 agtcaacgaa actgcctata cccaacccgc cctatttgcc ttagaatact cactctataa
    30301 attatggcaa tcttggggga ttaaaccgac tgcggtcatt ggtcatagtg tcggggaata
    30361 tgtcgcggct tgtgttgctg gcgtgttcag cttggaagat gggttaaaac ttattgccca
    30421 gcgtgccaaa ttaatgcaat ctctacctcc aggggggagt atggttgcag tcttagcaga
    30481 tgaaagcaca gttcgtctag ctatacaaaa ttatgcccaa gatgtaacca ttgcagcaat
    30541 taatgcccct gaaaatatag tcattgccgg taaacaagaa tcggtgcagg ctgtagttgc
    30601 catcttagaa caagaaagca tcaaaacccg caacctgaca gtttcccatg cctttcattc
    30661 gcccttggta gagccaattt tagaagaatt tgccgccaca ctccagcaaa ttacctttca
    30721 cgcaccgcaa attcccttaa tttccaacgt caccggcaaa gtcttctcac caggagaaat
    30781 tcccgatgtc gcctactggc aacgccacac ccgcgcccca gtcagattta tggacggggt
    30841 aaaaacctta tttgaacttg gctgcgaaat atttttagaa ctagggccaa aaccagtttt
    30901 ggttaacttg ggcaaacagt gccaaacaga aaacagtgca atttggctag cttccctcat
    30961 gcccgaaaag agtgattttc aggtactacc gaagagtaac cacacaggca gcacaacacc
    31021 caagaagaat gaaaaaaaca cctcctctcc tcctaacctg tcacctgtca cctgtcacct
    31081 gtcacctgtg tctcttcaca gcctatctac cttatacatc caaggtgtag caattaactg
    31141 gcaaggatta cagccagact atccacgcca acgcctctca cttcccacct acccctttca
    31201 gcgacaacgt tactggattg aacacaacaa catccccatg aatcccacac acgaaaatat
    31261 tccatctgtc aatacccaac gccaggaaga aatattagca caactgcgtt ctttagtcgg
    31321 gcaagtgctg caagttcctc cagataaaat agatgtaaac acaccattct tagaaatggg
    31381 tgcagactct atttttttga tggaaggggt acgcagcatc gaaaactctt ttggcgttaa
    31441 aattgccatt cgccagtttt ttgaagaatt agccaccatc aacgctttag ctacctatat
    31501 tgagcagcat attgcagtta gtgtagttag tgaaggacat cggcaagagt tagcaatacc
    31561 taagttggtc aatgattatt cttctgagtc tacgacggga caaaattttc cgtcgaattt
    31621 ggaggaagta tctactcaaa ctgttgccac aattgtccga gttgcaccca gtaacagcgc
    31681 aagtaacggc aatggtgcag cttcttccca ctcagacaca gccatagaaa ggattatggc
    31741 gcaacaactg caaatgatga cacaaatcat gtcagagcaa ttgcaggtgt tacgcggtac
    31801 tcccgcatca acccagccaa acttcacacc caccaatggt aacggtaaca gcaacggcaa
    31861 aagtaaaacc accaacggta acggtaacgg taacggtaac ggtaacagca aaggacacca
    31921 ccccccactc ccaactccca actcccaact cccaactccc aactcagcac ttctcaatcc
    31981 ccactcccaa aaacacctag aagacctcat ccaacgttat acccaacgca cccaaaaatc
    32041 caaacaaagg gcgcaagctt cccgccatca cttaggtgat aaccgtgctg tagctggatt
    32101 ccgcatggga attaaagaaa tgctctatcc cattgtcggg acacgttacc aaggcgcaca
    32161 tttttgggac ttagatggca acgagtatgt agatttagca atgggtttcg gcacacattt
    32221 atttggacat ggtgcgccgt tcctgattgc agctattaac gaacaactgc aaaaaggtgt
    32281 agctgtcggc ccccaaccag aactagcctt agaaactgcc gaattactgt gtgaactgac
    32341 gggtgcagaa cgggctacat tttgtcaatc aggttcagaa tcagtgatgg tagccttgag
    32401 attagcacgg actgccacca aacgcgatcg cattgctatc tttacaggtt cttatcatgg
    32461 gcattttgac ggggtattgg ctcaaccaga aggaatgtcc agcgtccccc ttggcaacgg
    32521 catcgccgct aataccgtca aagatgtttt agtcttaaac tacggcgacc ccaaagcttt
    32581 ggaaattctc caagcgcaaa tgcacaccct cgcggcggta atggtcgaac ctgtgcagag
    32641 tcgctttcct aacttgcaac cacgagaatt tttacaggaa ttgcgtcacc tcaccgaagc
    32701 agcagggaca gccttaatct ttgacgaaat tatgacaggc ttccgcatcc atccaggggg
    32761 agcgcaagcc cattttgggg tcaaggcaga tttagccact tacagcaaaa tatttggcgg
    32821 tggtctaccc ctagccgcag tcgcaggtaa agccaagttc atggacggta tagacggcgg
    32881 atattggcaa tttggcgacc aatcatatcc ccaagccgac cggacatttt ttgctgggac
    32941 atttaataaa catcccctag caatggcaac ttgtcgagcc gctttgaaat atttaaaaga
    33001 acagggtgta cagttacaaa ctaatttaaa tgctcggact gcctatctag tcgaacaact
    33061 caatcatatt ttcacagagc aacaaataga catccgggtg gtaaatttcg gctcactgtt
    33121 ccggtttgtc ttcaccgcta acatggatgt gttcttctac cacctcctag aaaaaggtgt
    33181 gtacatttgg gaaggacgca cctgttttct ctccacagcc cacaccgact cagatattga
    33241 gtggattatt caggcggtgc gagacagtat tacagaaatg cgctcaggtg gtttttttcc
    33301 ccacacccaa caggagaatg tcaccgtaaa aaagtctcca gcgtcgctgc caacagctaa
    33361 cttaaatcag ccagtaaata aagctggctt ttgggaacga cgcaaacaaa aaactacccc
    33421 tagggaaaaa actaactata ttcccagcca aaaagtacaa tttagcttgt actatttcgg
    33481 caactacgaa tcagaattta gccatgataa atatgaccta ttatttaccg gggctaaatt
    33541 tggcgacaaa aatggattta gtgccgtttg gattcctgag cgtcattttc atgcctttgg
    33601 cgggttttct cccaacccct cagtcattgc cgccgccatc gccagagaaa cccaaaacat
    33661 tcaaattcgc tccggtagcg ttgtcctccc catacaccat cccatccgag tagtagaaga
    33721 atggtcagta gtagataacc tttcccaagg acgcgtcggt atttccttcg cttccggctg
    33781 gaatcccaac gactttgtat tggcccccca atccttcggg aaacatcgag aactgatgtt
    33841 tcaacagatg gaaacagtcc gtaaattgtg gcggggggac tcaattcaag tgcagaacgg
    33901 agtcggtcaa accgttagcg tggaagtatt tcccaaaccc atgcaagccg aactgcaaga
    33961 ctggattacc atcgtcaata atccagacac atatatcaaa gctggagaaa tgggtgcagg
    34021 cgtattaacc aacctgatgg gacagagtgt ggaagacttg gcagaaaata ttgccctgta
    34081 ccgcgaatct ctagcacagc atggttatga tccctcagta ggcagagtta cagtattact
    34141 acatacattt gtcggtaaag acttagaaca aacccgccaa caagccagag aaccactctg
    34201 taaatatttt aaatcttccc tagctttatt ccaaaatctc gtgaaaactc aaggcttagg
    34261 gatagatttt gatagcctga gcgaagatga tcaagattat attttatcct ctgcttgcga
    34321 tcgctatatt caatctagtg cattaatcgg cacacctgaa acttgcgctc aagtcgtcgc
    34381 caaactgcaa gccatcggcg ttgacgaaat cgcctgttta atagactttg gcgtaaaccc
    34441 caccgcagta gtcgccagcc tcccagaatt aaacgacctc agagaactct atcaaaaccg
    34501 cccatttttc atcacagccc ccctcagcac cgcccaaaaa caactatggg tactagcgca
    34561 actgagtaag gaagcttcca ccgcctacaa cgaatcagtc agcctcaaac tccaaggtaa
    34621 actcaaccta ccagccttaa cccaggcgat gcagcaaata gtcaatcgcc acgaagcact
    34681 cagaaccagc atcagccccg aaggcgacgt gcagcaaatt ttcccctttg atttgtcctc
    34741 agaaactcct cctctccgcg cctctgcgcc tctgcgtgaa ttaaccccag aacccttcga
    34801 ccttaccaaa gcacccctct tccgcctcca cctcatccaa ctatccccag aagaacacag
    34861 actaaccctg accggccatc acatcatcgt cgatggttgg tcagtaggag tcatcctcca
    34921 agaactcagc accttataca cagccatctg tcaaggtaaa aaatgccaac tccctacccc
    34981 aatgcaatac cgggagtata tcaactggca aatccaacaa agccagacag aagaaatggc
    35041 aacccatgaa caatactggc tgcaaaaatt tgccgacacc atccctgcat tagacctacc
    35101 cagcgataga acacgcaccc ccatcaaaac ctatcgcggc agcaagcaaa gtttactgct
    35161 ccatagcgag ataggacgcg ccattaaaaa agtcagtcta gagcaaggtt gtaccttatt
    35221 tatgaccctg cttgcggtat acaccacatt actgcataga ttgacaggac aatccaatat
    35281 tattgtaggc attcccacag ccgggcgatc gcttccgggt agtgatagtt tagtcggtta
    35341 ttgcgctcac gtcttaccaa ttagcagcga ctaccaaagt acaaccccat tctcagaata
    35401 tctcttagct atcaggaacg tcttactaga agcctaccaa catcaggact atccctttgc
    35461 cgaactaatt caaaaattaa acctcaaccc agatgcgagt agatcacctc tagttactgt
    35521 tacattcaac ttagatagat caatcacact gcccaagtta gacgaactgg aaaccagttg
    35581 gttcactcaa cccatcaatt ccactgacta cgatattcat tggaatatca ctcagataga
    35641 agatgaacta attctagatt gccactacaa caccgattta tttgatgcca ctaccattga
    35701 acgatggttg ggacacttcc aaaccttact cacagcaatt attgccaatc cccgccaacc
    35761 tgtaggggaa ttaccactgc taacagcgac agaattacag caattgttag tagattggaa
    35821 cgctacccaa actgattatc ccgccgataa gtgcattcat caaatctttg aagcgcaagt
    35881 agaaaaaaca cctgatgcgg tagcagttat aggggacagg gaagagttaa cttatgctga
    35941 gttaaataac cgtgctaatc aagtggcgca ctacttgaga agacagggtg tagagtcagg
    36001 tgtcctcgtg ggtatctgta tgcagcgttc ccttgatttt atagtgggag tattgggtat
    36061 cctcaaagct ggcggtgttt atgtacccct tgacccagaa tatccccaag aaagattggc
    36121 ttggatgttg gaggatgtac agccgcaagt tttattaact cagacggatt taattgacag
    36181 attaccgaca tttacaaaca tcctgtctgt agatgcagca gccatcaaaa aggaatcaac
    36241 agaaaatctc gatacagagg tgacagccga caacttagcg tacatcatgt acacctccgg
    36301 ttcgactggc aaacccaaag gtgtcagcat tcctcatcgg ggagtcgtgc gattagttaa
    36361 agccacagat tatcttagct tcacttcaga agaaacctgg ctacaattag cccctatcag
    36421 cttcgatgct gcaaccttag aaatttgggg tagtttgctc aatggcagta aattagtcat
    36481 catgcccatt cccaaaccca gtttagaaga gatagggcaa ataatccaac aacaccaaat
    36541 caccacccta tggctaacag ccagcctatt ccatctgata gtagatgaac ggatagaaga
    36601 cttaaaaaca gtccgacaac tcatagccgg cggagatgta ctatcaatcc cccacgtcaa
    36661 gaaagtatta caacatctac cccaaattcg cctagttaac ggttacggcc ccaccgaaaa
    36721 caccaccttc acctgttgct accccataac cagtgacacc aacttagact catcagtccc
    36781 cataggtcgc cccatagcca acacccaagt ttacatcctc gaccccaacc tacaaccagt
    36841 ccccatagga gtctggggag aactccacac cggaggcgca ggactagccc aaggctactg
    36901 gaaacgccca gacttaaccc aagaaaaatt tattcaattg ggcgtagaga atagcactat
    36961 cacctatccc cagtccctca ctctctacaa aaccggcgac ctaacacgct atcgcccaga
    37021 tggaacaatc gaatttagag gacgcataga ccaacaaatc aaaattcgtg gcttccgcat
    37081 cgaactaggc gaaattgaaa ccaaactagc aactcatccc caaatcaaac agacagttgt
    37141 taccactcaa gctgatacct taattgccta cttcatcccc gaagctgaag caccgacaaa
    37201 cagcgaatta cgtcactatc tcaagcagca actaccagac tatatgctgc catcagcctt
    37261 tgtctgttta gataccttcc ctcttacacc taatggtaaa gtagaccgaa aagccttacc
    37321 agaagcagat ttagcaaaac aagcccatgt acaatatatt gctcctcgta ctgaaaaaga
    37381 gcaagcgatc gccacaataa ttgcctcagt tctcaactta gaaaaagtcg gaattgccga
    37441 taatttcttt gaaatcggcg gtaattcgtt gaatgcgatg caagtgactt ctcgcctgcg
    37501 gcaaactttc ggcgtggaat tacctttgcg ccagatgttg gaatcaccca cagttatgga
    37561 actgtccacc tacatcgagc aaattttctc aactatccaa aaattacagt ctacacctgt
    37621 ggagttatca gaaaatcggg aggaaattga agtatgaaac ccattgaaga atttttgtct
    37681 gaattaggaa acctggacat taagctatgg gtggaagaca atcccaattc ctcccaaggg
    37741 gtgaagctgc gctgtaatgc gcccagtggt agattaacac cagaaattcg tgctaatctg
    37801 agcgatcgca aggctgaaat tatcagcttt ttccaacggg taaacttaac ctctgaagtc
    37861 gaatcaattc ctaccgtagc gcgagacaac ggaaatttac ctctatcctg gtcacagcaa
    37921 cgcctttggt ttctctacca aatggaaggt gcaagtgcca cttacaatat gccggcggcg
    37981 gtgcaaatga ctggggtact ggatatctca gcattggaac aggctttaca agaaatcatc
    38041 cgtcgtcatg aggttttacg caccagtttt gcaaaggttg atggtcatgc tgtacaggta
    38101 attcatcctc acgctaacct gacactccca atagtcgatt tacaaggatg ctcagatcaa
    38161 gtcaaacaat tagccatcct cgatgcagag aaaccctttg acctcaccca agcacctctg
    38221 atgcgggtga cactcttaaa gctgagtgaa caatctcatg tgttgctgat gaatatgcac
    38281 cacattgtcg ctgatgggtg gtcaattggc atattaattc aagaaatatc tactttatat
    38341 acagtattta tacaaagtaa accttctcct ctcccagcat taccgattca gtatgcagac
    38401 tttgctgtgt ggcaaagaca atggttacaa ggggaagtat ttagtcaaaa aatcaactat
    38461 tggcaaaagc agctagctga tgcaccacca ctattagaac tccccaccga cagaccccgc
    38521 ccagccattc aaacattccg gggtagtagt cgagattttc ccttacctct ggaattgacc
    38581 gaacaactca atcgcctcag tcagaagttt ggggtgacgc tgttcatgac cttagaagca
    38641 gcctttgtca ccttactgca tcgttacagt ggtcagacag atattcttat tggtagcccg
    38701 atagctaacc gcgatcgccc agagatagat acactaatcg gcttttttat caatacattg
    38761 gtattgcgat cgcgtttaga aaataatccc ccattcatcg aattactgca acaagtcaag
    38821 caagtggcgt tagatgccta cgcgcaccaa gaagtcccct ttgagcagat agtagacata
    38881 ctacaactta agcgtaatct cagccataca cctttatttc aggtgatgtt tgccctgcaa
    38941 aatgcgccga tgggcaattt ggaattacca gggttgcagt tgtcgcagtt accaatagag
    39001 gctattacct ccaagtttga tttaactctg tcgatgacgg agactcccca aggactcatc
    39061 gggaattggg aatataacac cgacttgttt gattctgaga caattacccg aatggcggga
    39121 catttccaga atttattgac cgcaattctg gctaatcccc agcaaacggt acaggaatta
    39181 gcgttactaa gtaatgctga acggcaacaa atattaggag atgggtattc tactgctgag
    39241 tatattgtca atcaatgtct gcatcaacgg tttgaggagc aagcagaaaa aacaccggat
    39301 gctatagcgg taacttttgc tgaccaacat ctcacttatg ctcagttaaa tacccgtgca
    39361 aatcagttag cacattactt acaaactttg ggtgttgcgc ctgatgtgtt ggtgggtatc
    39421 tgcgttgagc gttccctgga aatgatgatc ggattattgg ggattctcaa agctggcggt
    39481 gcttatgtac cccttgaccc tgagtatccg cctgagcgtt tggcgtttat gttggatgat
    39541 tcccaggtat cggtgttgtt gactcaggct aagtggttag aaaatctacc cgtaacgaat
    39601 gctaagactg tttgtttaga tcaagattgg gaagatattc atacccatag tgtagaaaat
    39661 cctcagattg gggtgttacc tgagaattta gcttatgtaa tttatacatc tggctctacg
    39721 ggtaaaccga agggtgtgtt ggtgaatcac tgcaatgtga tgcggctgtt tgcagcgact
    39781 catgattggt ttaactttga tgctagcgat gtgtggacgc tgttccattc ctatgctttt
    39841 gatttctccg tgtgggaaat gtggggggcg ttgttgtatg gtggtcgatt ggtagttgtg
    39901 cctttttggg tgagtcgtga cccggaagaa ctttatcaga tgctacatca agaaggggtg
    39961 acagtattaa atcagacacc ttcggcattt cgtcagttga tttgggctga ggaagaacaa
    40021 ggtatatcta atcttagttt gcgatgggtg atttttgggg gagaggctct tgacccaact
    40081 agtttattac cttggtttga gcgacatgga gatgttactc cccaattagt gaatatgtac
    40141 gggattacgg aaactactgt acacgttact ttccgaaggt tgagtatggc ggatgcgggg
    40201 agtcctagca gtgtgattgg tgtaccgatt cctgatttac ggctgtatat tctcgatgag
    40261 catttgcagc ctgttcctgt tggggtcagg ggtgaaatgt atgtcggtgg tgctggggtg
    40321 acgcggggtt atttgcatcg tccagagttg acccagcaaa gattccttac cactccctac
    40381 tccccacgcc ctttatataa aactggtgat ttggcgcggt atttacctga tggtagtatt
    40441 gagtatttgg gacgcataga tgaccaggta aaaattcgcg gttttcggat tgagttgggg
    40501 gaaattgagg cgaagttagc aactcatccc caagtacggc aaactgtagt tttagtacaa
    40561 gcagatactc ccgacaataa acgcttggtg gcttactttg tggctgaggg tgaatctccc
    40621 agtagtggtg agttgcgaga ttatctcaaa cagcagttac ctgattacat gattccagca
    40681 gtgtttgtct gcttggatgc ctttccgttg acggctaatg gtaaacttga ccgacggatg
    40741 ttacctgttc cggaagttag accagagtta aatagtggtt ttgttgcacc ccaaacccca
    40801 gaagaagagt tattagccaa tatttgggca aaagttttag gggtgtccca agtcgggata
    40861 catgataatt tctttgaatt gggtggtgac tcgattcgca gtatccaaat tttggcgcag
    40921 gctaaccaag ttggtttaga cttttctcta caacagttat tccaacacca aactattgcc
    40981 gaattagcga cattggtaag caaagaagtc agttttactg tcacaccgca gacatcacct
    41041 tttagtttag tggctgaggt agacaaggag aagttaccag caaaattagc agatgcttat
    41101 cctctgacag cactgcaagc agggatggtt tttcatagtg aattgagttt agattctgct
    41161 atttatcatg atgtcttctc tttccatatg cgggcgactc tggatttatc agtgttgcag
    41221 actgcgattg agcaattgat ttttcgtcat gcggtgctgc gtactagctt tgaattgagt
    41281 gggttttctg agccattgca gttggtgcat caaaatatag atgtaccttt acaagtggat
    41341 gatattagtc atttaacaac ggctgaacaa caagccgcta ttaataattg gatagaaaca
    41401 gaaaagtatc atagttttga ctggaaaaaa ccgcctctgc tacgttttta tgtgcatcgt
    41461 cgcagtacgg aaacgtttaa tttaagtttt agtttccatc atgcgattct cgacggttgg
    41521 agtgtagccg ctttactgac ggaattatgg caagaatata taaatttact caaacatcaa
    41581 cccagttctc attccgcgat tcggacattg gcttttgggg attttgtggc gttggaacgt
    41641 caggctctac aatcagaagc aactcagcaa tattggctag agcaactggc tgatgttact
    41701 attactgaat taccacgctg gccggaatct catcgaaaag atgccaaagc agaaatagat
    41761 attgaggaag tagcaattac tgctgaatta tcagacggct tgaagcaact agctagcaaa
    41821 gctggtgttc ctctgaaaag tgtcctgttg gcggctcatg tccgggtatt aaatttactc
    41881 accaatcaaa cagatgtgtt aacggggttg gtggctaatg gaagaccgga agatgcagat
    41941 ggagaaaaaa ttcttggttt atttttgaat actttgcctt tgcgatcgca tttaggcggt
    42001 ggtacttggt tagaattgat ccagcaaact ttccaggctg aacaagcggc tttaccgcat
    42061 cggcgttatc ctttggctga gatgcaacgt ctgtgtggtg gagagcaatt atttgaaact
    42121 agttttaatt tcgttcattt tcacgtttat caaggaattc tcggcttaaa ggaatctgag
    42181 gttttagatt accaagcctt tgagcaaact aacttgactt tggtggcgca ctttagtgtt
    42241 aatccggttt cttcccagtt aaatttagcc ctgaattatc aaaccaatca actgtgtaga
    42301 gaacaagtag aaagtatctc tacctactac attaacgctt taatggcgat ggtagcagca
    42361 ccatcagcac tatatcaaaa tcaatcactg ctttcacccc aagaacaaca ccagttactc
    42421 gacgaatgga atgcgactga gagcagttat gatgattcgc tatgtctgca tcagctattt
    42481 gcagcacagg tgcaaaaaac accaaatgca atagcagtca catatgagca acaacatctc
    42541 acctacgcac aattgaatca gcgagccaat caactggcgc accatttaca aactctgggt
    42601 gtgaaacctg atactttggt aggtatctgc gttgaacgtt ccttagaaat ggtggtaggg
    42661 ttgttgggga ttttgaaggc tggaggggct tttgtacctc ttgacccagc ttatccacgc
    42721 gatcgcctac aatacttact ggaagattct caagtgcctg tattacttac ccagtcgcac
    42781 ttacttgaca ttctaccaga gcatcagcag gtgatttgtc tggatacaga ttggcaagcg
    42841 atttcccaac agagtcaagc caatcccgtt tcccaggtaa aatctactaa cttagcttat
    42901 ataatttata cctccggttc aactggcaaa cccaagggga caatgataat tcaccaaggg
    42961 gtagtgaatt atctcagttg gtgtactgaa gcttatgctg tagccgatgg ctatggcgca
    43021 cctgtacaat cttcttttgc ttttgatgca actattacta gtctgttttc acctttaatg
    43081 gtgggtaagc aagtggtgct gttaccggaa aggcaggaaa ttgaggcttt gtgtagcgtt
    43141 ctgcggtcta aaactcagtt tagcttggtg aaactgacac ctgctcattt ggaactactc
    43201 aatcaaatta ttcccccagc agcagccgcc ggacaaacca acgcttttgt gatcggtggt
    43261 gaagccctct taggtaagac tttgcaattc tggcggcaaa acgcacccca aacccgacta
    43321 attaatgaat atggcccgac agaaaccgtt gtgggttgct gtatttatga agtgacagat
    43381 gacacttcgt taacagaggg cattttaatt ggtcgtccta ttgctaatac ccaactttat
    43441 attttggatg aatacctgca accagtcccc attggtgtca gaggtgaact ctatattggt
    43501 ggagctggtg tggcaagggg ctatttaaat cgtcctgagt tgacaaaaga gaaattcatt
    43561 tctcacccct tcattcatga accaggcgca cggttgtata agacgggaga tttggcacgt
    43621 tatcaacccg atggaaatat tgaatacctc ggaaggacag atcaccaagt aaaagtacga
    43681 ggttttcgga ttgagttggg agaaattgaa caagcgatcg ccaaatatcc gcaaattcgt
    43741 gaagttgttg tgatggtgcg ggaagatcag ccaggggatc aacgtttggt ggcttacata
    43801 gtagcgacag aaccacctac cgatagcgaa ttacgtgaac acctcaaaaa acagctaccg
    43861 gattacatga taccaacagc atttgtgtat ctggatgttt ttcccttgac agctaacggt
    43921 aaacttgacc gtcagtcctt acctgtaccc acgcaaatac agaagataac tactaatttt
    43981 gttttacccc gaacagatac agaaaaggcg atcgctgatt tattttctct gcttttaggc
    44041 gttaaaaacg ttagcatcta cgataatttc tttgagttgg ggggacattc cctgattgca
    44101 actcaagtaa tttctcgtct gcgggaaacc ttccaaatcg agttaccttt gcgggtgttg
    44161 tttgaatccc ccagggttat agaactggcg gaagttatca atagtcaacg ccaaacgaac
    44221 ttagaactaa ctgcaccagc actgacaccc gtatctagag aaaatctcga tattccttta
    44281 tcttgggcgc agcagcgact atggttttta gagcaattag aaggtggtag tgccacttac
    44341 aacgtaccgg cagccttcca attggaagga agactaaatg tcaccgcttt agaacaagcc
    44401 ttagaggaaa ttatccgtcg tcatgaaacc ttgcggactt gctttagatt ggtgaatggc
    44461 acaccagtac aattcattga tactaacgct actatcacct taaaagttac agacttgcag
    44521 caattaccaa cgccggaaca gactacagaa gtccagcgtt tggcagtatt agcagctgaa
    44581 acacccttta atctccagca cgctccattg ttccgagtta cattgttacc cttgggtgaa
    44641 gaatcccatg tgttactgat gacgatacac catatcatct ctgatgggtg gtctgtgggt
    44701 atcttcatcc aagaactatc aactctctat caagctttct cggctggcaa acccgctcca
    44761 ttgccagcgt tacctattca atatgctgac tttgctattt ggcaacggca atggttaagt
    44821 ggagaacttt taaaagctaa acttaactac tggcaacagc aattagcaga tgcacctcct
    44881 ttattagaat tacccacaga tagaccacgt ccagcaatca aaactttccg gggtaacaaa
    44941 caagactttg caatatcctt gcagttgagt gaaggaatta aagatttgag tcaacagcac
    45001 ggggtaacac tgtttatgac tctgcaagca gcctttgcca ccttactgca tcgttacagt
    45061 ggacaaactg atattcttgt gggtacaccc atcgctaacc gaaatcgtgc cgaaatagaa
    45121 ccattgattg gcttttttgt caatactttg gtattgagaa cccaaatttg cgataatccc
    45181 agttttgctg agttactcca acaagtcaaa cgggtagcgt tagatggcta tgcgcaccaa
    45241 gatgtcccct ttgagcaggt agtagaagtc ttacagccag aacgtaacct gagctatacg
    45301 cctctgttcc aggtaatgtt tgccttgcag aatgctccct tgggcttgga taatttggaa
    45361 ttagcaggtt tgagcctgac acctttactg attgagacgg tgacagccaa atttgattta
    45421 accctgtcaa tggaagaaac cccagaggga ttaattagca catgggaata taacaccgac
    45481 ttgtttgatg atgagacaat tacccgaatg gcgggacatt tccagaatat attgacagca
    45541 attctggcta atccccagca aacagtacag gaattagcgt tactaagtga tactgaacgg
    45601 caacaaatat taggagatgg gaagcctact gctgagtatg ttgtcaatca atgtctgcat
    45661 caactgtttg aggagcaagt acaaaaaaca ccggatgcta tagcggtaac ttttgctgac
    45721 caacatctca cttatgctca gttaaatacc cgtgcaaatc agttagcaca ttacttacaa
    45781 actttgggtg ttgcgcctga tgtgttggtg ggtatctgcg ttgagcgttc cctggaaatg
    45841 atgatcggat tattggggat tctcaaagct ggcggtgctt atgtacccct tgaccctgag
    45901 tatccgcctg agcgtttggc gtttatgttg gatgattccc aggtatcggt gttgttgact
    45961 caggctaagt ggttagaaaa tctacccgta acgaatgcta agactgtttg tttagatcaa
    46021 gattgggaag atattcatac ccatagtgta gaaaatcctc agattggggt gttacctgag
    46081 aatttagctt atgtaattta tacatctggc tctacgggta aaccgaaggg tgtgttggtg
    46141 aatcactgca atgtgatgcg gctgtttgca gcgactcatt taactttgat gctagcgatg
    46201 tgtggacgct gttccattcc tatgcttttg attctctgtg tgggaaatgt ggggagcgtt
    46261 gttgtatggc ggtcgattag tggttgtgcc tttctgtgtg agtcgtgacc ctggggagtt
    46321 ttatgagttg ctttgtcggg agggggtgac agtattaaat cagacacctt cggcttttcg
    46381 acagttgatt tgggtggaaa gttcacatag aggaggagat gagaggattg ctttgcgatg
    46441 ggtgattttt gggggagagg ctcttgaccc aactagttta ttaccttggt ttgaaagaca
    46501 tggggatgct tgtccgcaat tggtgaatat gtacgggatt acggaaacta ctgtacacgt
    46561 tactttccat cagttgacta tggcggatgc ggggagtcct agcagtgtga ttggtgtacc
    46621 gattcctgat ttacggctgt atattctcga tgaacatttg cagcctgttc ctgtgggggt
    46681 acgaggtgaa atgtatgttg gcggtgcagg agtaacacgg ggttatttga atcgtccaga
    46741 gttgacccaa gaaagattta tccgattggg gactagggat aatactgtca cctgtcacct
    46801 gtcacctgtc acctataacc ctctctacaa aacaggtgat ttagctcgct atttagctga
    46861 tgggaatatc gaatacctcg gccgcataga tgaccaggtg aagattcgcg gttttcggat
    46921 tgagttgggg gaaattgagg cgaagttagc aagtcatccc caaatacggc aaactgtagt
    46981 tttagtacaa gcagatactc ccgacaataa acgcttggtg gcttactttg tggctgatgg
    47041 tgaatctccc agtagtggtg agttgcggga ttatctcaag cagcagttac ctgattacat
    47101 gattccggct gtgtttgttt cactggatgc ctttccgttg acggctaatg gtaaacttga
    47161 ccgacggatg ttacctgtcc cggaagttag accagagtta gatactggtt ttgttgcacc
    47221 gcaaaatgaa aaacaagaat tattagctag catttggacg gaagttttag gggtgtccca
    47281 agttgggata catgataatt tctttgaatt gggtggtgac tcgattcgca gtatccaaat
    47341 tttggcgcag gcgaatcaag ttgggttaga tttttctctt cagcagctat ttcaatacca
    47401 aactattgcg gaattggcgg agttggtgag taaggaagtg agttttacgc tgacaccgca
    47461 gacatcacct tttagtttga ttgcggagat agacaagcag aagttagccg caggattgga
    47521 agatgcctat cctctgaccg cattgcaagc cggaatggta tttcacagtg agttgagtgc
    47581 agattctgct atttatcatg atgttttctc tttccatctg cgagcgactc tggatttacc
    47641 agcgttacac actgcgattg agcaattgat ggctcgttat gcggtgttgc gtactagctt
    47701 tgaattgagt gggttttctg agccgttgca attagtgcat caaaatgtgg atgtaccttt
    47761 gcaggtggat gatatcagtg atttaacaat ggctgaacag caagccgcca tcgatgcttg
    47821 gatagaaacg gagaagtatc gccattttga ttggacacaa ccgcctctgt ggcgttttga
    47881 tgttcatcgt cgtagtgggg aaacttttaa tttaagtttt agtttccacc atgcgattct
    47941 cgatggttgg agtgtggcat ctttactcac ggaattgtgg caacaatatt taaacttact
    48001 caaacccaac ccaatcccta atccccaatc cccagtcccc acacttgctt tccgtgattt
    48061 tgtggcatta gaacgtactg ctttacaatc ggaaacgaca caacaatatt ggctcgaaca
    48121 actccgtgat gtcacaatta ctgaactacc acgctggccg caatcctatc ttgaggaggc
    48181 tgaggaagag gtaagtattc aagaagtcgc aattagtgct gagttgtcag acggattgaa
    48241 gcaactggct cgcaatgcta gtgttcctct gaaaagtgta ctgttggctg ctcacttacg
    48301 ggtattgaat ttactgggca atcaagcgga tgtattgacg ggtttggtgg ctaacggtag
    48361 accggaagat gcagatgggg aaaagattct agggctattt ttgaatactt tgcctttgcg
    48421 atcgcattta ggcggtggta cttggttaga attgatccag caaacttttc aagctgaaca
    48481 agcggcttta cctcatcggc gttatccttt ggctgagatg caacgtctgt gtggtggaga
    48541 gcaattattt gaaactagtt ttaatttcgt tcatttccac gtttatcaag gtgttttggg
    48601 gttagaggaa tctcagcttt tagattctca gacttttgag caaactaatt ttaccttggt
    48661 agctaacttt gggttggatt tggtttcctc tcatgtcaat ttagctctga gttataagac
    48721 taatgaactg tgtagagaac aagtagaaag tatctctact tactatctga atactttaat
    48781 ggcgatggta gcagcaccat cagcactata tcaaaatcaa tcactgcttt cacccacaga
    48841 acaacaccag ttactcacgg atggaaatgc gactgagagc agttatgatg atcgcttatg
    48901 tctgcatcag ctatttgcag cacaggtgca aaaaaacaca aatgcaatag cagtcacata
    48961 tgagcaacaa catctcacct acgcacaatt gaatcagcga gccaatcaac tggcgcacca
    49021 tttacaaact ctgggtgtga aacctgatac tttggtaggt atctgcgttg aacgttcctt
    49081 agaaatggtg gtagggttgt tggggatttt gaaggctgga ggggcttttg tacctcttga
    49141 cccagcttat ccacgcgatc gcctacaata cttactggaa gattctcaag tgcctgtatt
    49201 acttacccag tcgcacttac ttgacattct accagagcat cagcaggtga tttgtctgga
    49261 tacagattgg caagcgattt cccaacagag tcaagccaat cccgtttccc aggtaaaatc
    49321 tactaactta gcttatataa tttatacctc cggttcaact ggcaaaccca aggggacaat
    49381 gataattcac caaggggtag tgaattatct cagttggtgt actgaagctt atgctgtagc
    49441 cgatggctat ggcgcacctg tacaatcttc ttttgctttt gatgcaacta ttactagtct
    49501 gttttcacct ttaatggtgg gtaagcaagt ggtgctgtta ccggaaaggc aggaaattga
    49561 ggctttgtgt agcgttctgc ggtctaaaac tcagtttagc ttggtgaaac tgacacctgc
    49621 tcatttggaa ctactcaatc aaattattcc cccagcagca gccgccggac aaaccaacgc
    49681 ttttgtgatc ggtggtgaag ccctcttagg taagactctg caattctggc gagaaaacgc
    49741 cccagaaact cgactaatta atgaatatgg cccgacagaa actgttgtgg gttgttgcat
    49801 ctatgaagta acagatgaca cttcgttaac agaggggatt ttaattggtc gtcccattgc
    49861 taatacccaa ctttatattt tggatgaata cctgcaacca gtccccattg gtgtcagagg
    49921 tgaactctat attggtggag ctggtgtggc aaggggctat ttgaatcgtc ctgagttgac
    49981 aaaagagaaa ttcatttctc accccttcat tcatgaacca ggcgcacggc tgtataagac
    50041 gggagatttg gcacgttatc aaccagatgg caatattgaa tacctcggaa ggacagatca
    50101 ccaagtaaaa gtacgaggct ttcgcattga gttgggagag attgagacag ccgtcaatca
    50161 acatccccaa gtcaaacaag tggcgataat tgtccgggag gatcaaccag gcgaccaacg
    50221 tttagtagcc tacctcattc cagacgggga agcaccaaca agcgacgagt tgcgaaacgc
    50281 cctcaaacag caactccccg actacatgat tccgactgcc tttgtagtgc ttaatacttt
    50341 acctctcaca cctaacggca aactagaccg gaatgctctc cccatcccag atattaatat
    50401 cacttccgaa aactttgtct taccgcgtac acaaacggaa gtcttaattg ctgacctctt
    50461 cgcctcactc cttggaatca aacaagttag cattcacgat aacttctttg ccttgggggg
    50521 acattcccta ttagctacac aagttatttc acgtctgcgg gtaatcttcc gcattgaagt
    50581 acccctacgg ttattatttg aatctcccac agtagcggaa ctagaccaag ccatccataa
    50641 actacagcaa acggactcag ggttactctc accacccctt gttcctgtca ctagagataa
    50701 tcaacccata cctctatcgt ggtcacagca acgactatgg tttttagccc aattggaatc
    50761 cagcagtggc acatacaatg tacctgcggc tttacaattg caaggatact taaatgttgc
    50821 agctctagag caagcattgc aggaaattgt ccatcgtcat gaagttttgc ggacaagttt
    50881 tcccaccatc aacggcgtac ctacccaagt aattgttcct gctgtgactg tgacactccc
    50941 actcatagat ttacagggat taccagaaca agctgaacaa gttaagcaac tgacaatcac
    51001 taactcacaa acaacctttg acctcgccat tgctccctta atgcgatcgc agttgttgcg
    51061 tttgggtgaa cagtctcata ttctattaat taacctgcat cacattgttt gtgatggttg
    51121 gtctgtgggt gtattcatcc aagaattatc agcactgtat accgccttca ctgaggaaaa
    51181 accctccccc ttaccagagt tagcaattca gtatgctgat tttgcagtat ggcaaagaca
    51241 atggttgagt ggagaagtat tagagaaaaa actcaactat tggcaacaac agctagcagg
    51301 tgcgccacca ctgttagaat taccaattga tcgcccccgt ccaccaatcc aaagttatca
    51361 agggggttac tatgggttta cactggatgc tgacttgaca gcaaaactca agagtttgag
    51421 tcaaaaatct agcgttaccc tatttatgac cctgcaagcg gcatttgtaa cgttactgca
    51481 tcgctacagt ggacaaacag atatactcgt tggtacaccc attgctaacc gcgatcgcaa
    51541 agaaacagaa tcattaattg gcttttttgt caacactttg gtattgagaa cccaaattac
    51601 agacaatccc aagtttgcgg aattactgca acaagtccgg cgagtgtcgc tagaggctta
    51661 tgcttaccaa gatgtcccct ttgagcaggt agtagaagcc ttacagccag aacggaatct
    51721 gagccacagt cccctgtttc aagtgatgtt tatttggcaa aataccccct cccaaaattt
    51781 tgaattacct ggtttgagtc tcacaccttt acctattgag acagttacag ccaagtttga
    51841 tttaaccctg tcaatggaag aaactcccca aggtttagcc gggggatggg aatataacag
    51901 cgatttgttt gatttagcaa ctattgaacg tattgctcat cacttccata atttactaat
    51961 agcagtcacc acaaatccag aacagcctgt gggtttatta cctctgttaa cagctagtga
    52021 agaacaaaaa atactagttg attttaatca tacagaggct gattatccca ctgatttata
    52081 tttacaccaa ctatttgaag cccaggtaga acgaacacct gatgccgtgg cggtaggaat
    52141 cgggactggg gaagagttaa cttatgctga gttaaatact cgtgctaatc aactagcttg
    52201 ttacctacag tttttgggtg tgggtaatga gaaagtggta ggaatttgtg tagaacgttc
    52261 cctagatatg attgtgggtt tgttagcaac tctcaaagct gggggtgctt atgttcctct
    52321 tgaccccaaa tacccggcgg aacgtttggc gttcatggta gaggatgctg aaattgaggt
    52381 gctattaaca caacagcctc tagtagattt actgccaaaa acaatggcaa aaattatctg
    52441 tttagataca gagtggctag caatatctgc ctactctccc cacagcccac agcccactac
    52501 ccattccccc aatcatctag cttatataat ctacacatct ggttctactg gtaaacccaa
    52561 aggcgtgcaa attattcaca gtgcggtggt caacttctta acctcagtag cgcaagaacc
    52621 aggaattaca gccgcagatg tggtactttc cgtcaccact ttatcctttg atattgcggt
    52681 actagatatt ttcttaccat tgatggtagg agcaaaggtg gttttagtta gtaccgagat
    52741 gactaaagat ggctacgcat tgcaaaagtt gctactggaa tctcacgcta caatcatgca
    52801 ggcgacacca gccacttggc gaattttgtt agcttctggg tggaatggta cagaaaaatt
    52861 aaaaatatta tgtgctggtg aagccctacc cagggattta gctaatcaac tactcgccag
    52921 aagttgtgaa ctctggaatg cttacggccc gacagaaact actacctggt caacagttta
    52981 tcaagtagaa ccaggtgaag gtaaagtatt gattggtcat cccctcggca atactcaaat
    53041 ttatctgctg gatacttacg gacaacctgt accaattgga gtcgctgggg aattgcatat
    53101 tggtggtgca ggattagcga gaggttatcg taaccgtcca gaattgactg cggagaagtt
    53161 tatttccagt ccctttcagg aagagaaatg tctgtataaa accggagatt tagcccggta
    53221 tttaccagat ggcaatattg aatacctagg acgaattgac aatcaagtaa aattacgggg
    53281 ctttcggata gaattaggtg aaattgaagc cggaattatt gcccatcccc aagttaagca
    53341 agccgtcgtc atcatccgcg aagaccagcc gggaaggaaa cttttagtag cttatgtcgt
    53401 ttctcaacag gaaacaccga ctagcagcga attgcgtaat ttactgcaag agcaacttcc
    53461 tgagtacatg attcccaatg tctttgtatt cctagaagct ttacccctca cacccaatag
    53521 taaaatagat cgtcgcgccc tccctgcacc agagttagaa gctagcaacc aagatgatgt
    53581 agttaaaccg cgtaaccaca ttgaagaaag tttggctaat atctggggtg aaatcctggg
    53641 actacaacaa gtcggtattc atgataactt ctttgagttg ggtggcgatt ccatcattag
    53701 tattcaggta attgctcgcg ccaatcaagc agggatacag ctaacactca agcagatatt
    53761 ccaacatcaa acaattgctc agttagcagc agtctgcaca atgggtagta tcccagcaga
    53821 acaaggttta gtcactggag aattaccttt aactccgatt cagcattggt tctttgcaca
    53881 aaattcaccc caaccagacc acttcaatca atctgtacta ctagaagtac agccagattt
    53941 gcagccagaa ttattacagc aggtagtcca aaagctatta gaacatcatg atgctttacg
    54001 gctgaagttc tggcgcgatg attcccaatg gcagcagatt aatagcgatg ctgtcaatac
    54061 tgtacctttt gatgtgatag atttatcaga gcttagtccc aaacagcaac aagagacaat
    54121 cacagcatta gcagcaaaat tacaagctag cttgaatgtg tccgcaggtg aattaatgcg
    54181 ggtagtgctg tttaagttgg agacagataa acccagtcaa ttactcatca tcattcatca
    54241 cttagcggta gatggagtct cctggagaat tttattagaa gacttttcga ctgcatacca
    54301 acaactcagc cgtggagaaa ctattcaact accacccaaa acaaactcct ttaaagattg
    54361 ggcaacacat ttacaagaat atgggcaatc gcctgctcta aaatcagaaa tagcatactg
    54421 gctcacccag tcccataatc tccccctacc agtagactat cccaacggta aagcccacaa
    54481 caccgttgct agtgcgactc aagtatcagt tagtctcagt gaagaagaaa ctctagcact
    54541 gctacaagaa atcccccaag tctacaatac ccagattaac gatattttac taactgcctg
    54601 cctccaaagt tttaataatt ggacaggtaa caattcactc ctcatcgact tagaaggtca
    54661 cggaagagaa gaactctttg cagatatcaa catctcccgg acagtaggtt ggttcacttc
    54721 cattttcccc attctcctat cacttgacac aactcccttc ctcagagact ccgcctctct
    54781 gggtgaaacc aatcaaaacc caggagaagc cctaaaatcc atcaaagaac aactacgcag
    54841 cctaccccag aaaggcatag gctacggaat cctacgctat ctcagtgatg acgaacagat
    54901 gcgccagcta gccagtaaag ccgaggtatg tttcaactac ctaggacaat ttgaccgcat
    54961 cccccccgga attatccaag gctttgccaa aacatccacc ggagcaactc aaagttcttt
    55021 atcccatcgt ccgcacttat tagaaatcaa tggaattgta gcagaaggca aactacacat
    55081 caatttgact tacagcgaaa aagtgcataa acaaagcacc attgaacacc tagccaacga
    55141 tttcatcacc gccttacaaa cactcatcca ccactgtcag tcagccaccg gcggatacac
    55201 cccatctgat tttcccgcag ccgagttaaa tcaagacgag ttggatgctt tgttagcaga
    55261 aatcgatgaa taaaagtagg ggagacaaac taattcaata aattacgaat tacgaattac
    55321 gaattacgaa ttaaaaggaa accatgacca tctcagaaca accagccaaa agtaaaaacg
    55381 tcgcggctat ttatccgttg tcgccaatgc agcaagggat gctgtttcat actctgtact
    55441 cgccggagtc gggtatttac tttgagcaat ttatttgcac aattagcggt aacttaaatg
    55501 tggcagtgtt taagcaggct tggcaacaag tagtagagag acatcctgta ttaagaacgc
    55561 tgtttgtgtg ggaaaatcgc aaaaaaccct tacagattgt ccgccatcaa gttaccttac
    55621 cctggactga gtgcgattgg cgtttacttg ctccctcgga acagcaaaaa caagtagaag
    55681 aatttttggt gagcgatcgc actcaaggct ttaaattaga tcaagctccc ctgatgcgct
    55741 gtgctttgtt gcgactggga gaaaatactt atgaactggt tgctagtttt catcacttat
    55801 tagtagatgg ttggtcacta ccgattctgt ttcaagaagt gtttactttc tacgaagctg
    55861 gaaatcgtgg tgagcgtcta tctttagcta ctccccgtcc ttaccaagag tatattactt
    55921 ggttgcaacg tcaagatatt gctgcggcgg aaaacttttg gcggcaaaac ttacaagggt
    55981 ttactgcacc gacacctcta ggaggaaacc ggggtgtaca tcatcaaggt aattttttag
    56041 acataacttt tgagttatca tcccagatta cggataccct acaaagtttt gctcaacagc
    56101 accgtgtcac cctttctact ttagtacagg gagcttggtc aatattactg agtcgctaca
    56161 gtggggaatt ggatgtagtt tttggggcta cggtatccgg tcgtcctcca actttggtag
    56221 gggtggaatc aatggtgggt ttgtttatta ataccctacc ggtgcgggta caaatcccgg
    56281 aagatacggc gattgtacct tggttgcaat atttacaaac ccagcaaata gaacgagagc
    56341 catattctta cagtcccttg gtcgatattc acggctggag tgaaattcca cggggaatgt
    56401 cgttatttga aagcttggta gtatttgaaa attacccagt agatgcagca ctacaagaac
    56461 ctttagcaag tttagaaatt gatcatgtcc gggtttttga aattaataat tatcctttaa
    56521 ccttagtagt agcagcgcag cagacattat ctggcaagat tatatatgat agcgatcgct
    56581 tcgatgctga tactgttacc cgcatgatgg ggcattttca aaatttatta actgcgatcg
    56641 ttactcagcc agagttacca attacacaag tacctttaat tagcaataca gagaaacaac
    56701 agttaatctc agcctgggat gcccataaaa cagaatactc tagcaattac tgtttacatc
    56761 aattgtttga gcagcaggta gaaaaaacac ctgatgccgt ggctttagta tttggtgagc
    56821 aaagtctgac atacagtgag ttaaatgtgc gtgctaatca attggcgcat catttgcaat
    56881 ctttgggtgt caagcctgag acgctggtgg gtgtctgcgt ggaacgttct tttgagatga
    56941 tggtggcttt actagggatt ctcaaagctg gcggtgcata tctccccctt gacccagatt
    57001 atccggctga acgtttggag tttatgctgg cggatgctca agtatcggtg ttggtaacac
    57061 agtcgcaatg tttggatatt ttaccgattt tttctgctaa caaggtttgc ttggatacag
    57121 actggcaagt tatcagcact ctcagttcag aaaatccggt gagtcaagcg ataccggaga
    57181 gtttggctta tgtgatttat acctctggct ctacgggtaa gccgaagggg gtaatggtca
    57241 atcatggcaa tgtgactcgt ctatttgcgg cgacgcagga ttggtttaag tttgatgcta
    57301 gggatgtttg gactctgttt cattcctacg cttttgattt ctcggtgtgg gaaatgtggg
    57361 gggctttgtt gtatggcggt cggttggtga ttgtgccttt ttgggtgagt cgtgacccgg
    57421 aggcgtttta tgatttgctg ctgcgggagg gagtgacggt gttaaatcag actccttcgg
    57481 cttttcgaca gttgatttgg gtggaaaatt cacgcagaga cgcggaggcg cagagaggag
    57541 gaaatgagag gattgctttg cggtgggtga tttttggggg ggaggctctt gacccaacta
    57601 gtttattacc ttggtttgaa agacatgggg atgcttgtcc gcagttggtc aatatgtatg
    57661 ggattacgga aactactgtt catgtgactt ttcgtccgtt gagtatggcg gatgctggga
    57721 gtcgtagtag tgtgattggt gtgccgattc ctgatttgca agtctatatt ctggatgagc
    57781 atttgcagcc tgttcctgtt ggggtgcggg gtgaaatgta tgttggtggt gctggggtag
    57841 cacgcggtta tctgcatcgt ccagagttaa cccaagaaag atttatccga ttgggtatta
    57901 ggaataatcc tgtcacctat aaccctctct acaaaactgg tgatttggct cgctatttac
    57961 ccgatgggaa tattgaatac ttgggacgaa ttgaccatca agtaaaggtt cgcggtttcc
    58021 gtattgagtt gggagagatt gaggcggcgt tgaatcaaca tcctgtggtg caggaaaatg
    58081 tggtgattgc tcgtgaagat actccaggaa atcaacgttt ggtagcttat attgtggctg
    58141 atgcggttaa gtctgagtct ccacaaatcc ccagcactac caaagaaacg acttggacaa
    58201 gtccccaact attaattaat gaactgcgtc agcatctaga gggacaatta cctgattata
    58261 tgattccctg ggcttttgtg ctgctggata gtttaccgct aactaccaac ggtaaactag
    58321 accgccgcgc ccttccatcc ccagatttag atcaaaatcg ccacactagt tttgtctccc
    58381 cacaaactga aacagaacag gcgatcgctg atatcatatc ctctgtacta gaaattacca
    58441 aaatcggcat tcatgataac ttctttgaac taggtggaca ttccctcttg gctactcaag
    58501 tggtttcccg cttacggcaa actttcacca ttgagttacc cgtacaaact atttttcaga
    58561 gtcccaccat cgccggacta gcagaaatag tcattggtaa acaattagaa caagtagatg
    58621 atgatgcctt ggcacagatt ttagctgaag tcaatcagtt atcatcccaa gaagtcaaac
    58681 tgcaattaaa taaagatgag agcatttaat taactcatcc tctcccctac gcccctctgc
    58741 gttgaaaatt ccctagctac ttattgcaca aatgcccaga caatagtatc gtaaatttcg
    58801 tgtgtgctga atcacatcac cataagattt ttatgtacgg ctgatgcaaa ctctgtgttt
    58861 gaatcgtcgc tattgtcatg acttgttctg atacaaattc ccaattaatc agccccttta
    58921 tttgtgtagc cactaggttt aaaagggttt tgcaaaataa agttttaaca tgaatttatt
    58981 tagtagagaa ttctggaaac aatttttagc gatcgccaaa ccttattggt atcctagagc
    59041 tactgaagat agaaaattta tcaaggtttt atcgtcctgg ttgttgctgg ctttggcaat
    59101 tggtctagtt atagcaacta acgccatcaa cgtctacaat agttttgtca ccagagactt
    59161 aattgactta ctcgaagagc gagacatacc tgctttcttt cggctgttat tcatttatgc
    59221 taatctgctg attatcttga tacctttagt tgggattttg caatatttga aaaaaaagat
    59281 tgccctagat tggtatcaat ttttaaataa tcacattcta gataaatatt ttcaaaatcg
    59341 cgcctattac agagttaatt ttcgtacaga aatcgaaaat ccagaccaaa gaatcgctca
    59401 agaaatagaa caaattccgc aaattgctac gcaaatcttc tttgtggtag tagaaaaaac
    59461 tttggaaatt gtgagttttt tagcagtgat ttggtctatc tatagacctg tagcagtgat
    59521 aatagttatt tatgggatat taggtaatat tgttgctggg tatctcagtc aaagattaat
    59581 taaaattagc actgctcaat tagaaggtgt cgctgattac agctatagct taactcacgt
    59641 ccgcaacaat gccgaatcgg tggcattttt ccaaggcgaa gaacaagaag cagatatagt
    59701 taagcgcaga tttgctaaat taatggacgc taaaaaacaa atgattggat ggttgcgaga
    59761 ccaacaagta tttgtcacca gctatcaatc ttttttgagc atattacctt ttcttggcat
    59821 tgcaccatta tattttttca atcaaatcga attaggagaa gtgagccaag ctagtacagc
    59881 ctgtagtatt tttgctggtg cattatctgt gttggtgaca gagtttggtg gttctggtaa
    59941 gtttgtcaat ttggtggaac gattatctac tttctcagct attttggaag tcactaaggc
    60001 taagaaaaca ggtaagaaaa ttgagacatt agaagccaat cgattggaat tgcaaaattt
    60061 gaccttacaa actcccaact acgagagggt aatagttaaa gatttatcag tggttgtaga
    60121 atcgggtaag ggtctattaa tagtaggggc tagtggccgt ggtaagagtt ctttattgcg
    60181 agcgatcgcc ggtttatggg aagctggcac tggtcgcatc atcagaccta aactagaaga
    60241 aattttgttt ttaccccaac gtccctattt aattttagga actctccgcg aacagctttt
    60301 atatcccaac caaaatcgtc aaatgaaaga cgaagaatta gaacaagtct tacaacaagt
    60361 taacctctcc gatttaacat ccagagtagg tggctttgat gcaaatgttt attgggaaaa
    60421 cattctctct ttaggcgaac aacaacgcct agcttttgcc agattattag taattcgtcc
    60481 ccgctatgta attttagacg aagcaaccag tgccttagat ttaaagaacg aagagaaact
    60541 ctatcaacag ttgcaacaaa gcggtacaac ttttattagc gtgggacacc gagagagttt
    60601 gtttaattat catcaattgg ttttggaact ctcagaagag tcaaattggc gactcgtccc
    60661 catagaagag tacagtatta accgcgaatt cattcagcta tcggagacag aacccataaa
    60721 ggtgctagaa attgtacctg ataaactcca gtcggaagac tcaaaattga cggcactcaa
    60781 aattgacgga ttacgaaaat tatgtaaaga aaaaggtatt aaatggcgca atgcacgtgg
    60841 tacaggtaaa cacttaacca aaggcgaaat gttagccatg ttgaacgaaa ttgtggtctg
    60901 a
//
