LOCUS       BGC0001956             29240 bp    DNA     linear   BCT 12-JUN-2019
DEFINITION  Streptomyces miharaensis culture ATCC:19440 miharamycins
            biosynthetic gene cluster, complete sequence.
ACCESSION   BGC0001956
VERSION     BGC0001956
KEYWORDS    .
SOURCE      Streptomyces miharaensis
  ORGANISM  Streptomyces miharaensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:36:50
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 29240
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..29240
                     /country="Japan: Mihara City, Hiroshima Prefecture"
                     /culture_collection="ATCC:19440"
                     /db_xref="taxon:285483"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces miharaensis"
                     /strain="MS-1242 [SF-489]"
     protocluster    1..29240
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[11578:14665]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      11579..14665
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     protocluster    1..29240
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[9143:11582]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      9144..11582
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     cand_cluster    1..29240
                     /SMILES="NC([*])C(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="interleaved"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..29240
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001956"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..29240
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            152..1057
                     /gene="mhr1"
     CDS             152..1057
                     /NRPS_PKS="Domain: Aminotran_4 (38-273). E-value: 7.2e-34.
                     Score: 109.4. Matches aSDomain:
                     nrpspksdomains_mhr1_Aminotran_4.1"
                     /codon_start=1
                     /gene="mhr1"
                     /note="branched-chain aminotransferase"
                     /product="Mhr1"
                     /protein_id="QCX41907.1"
                     /transl_table=11
                     /translation="MPWEEATIHISSVGHASVSAAFEGVHSYWSETRGALYGFRFRDHM
                     QRLLDSLRLGRLEPEFDADALVAAAAELLASWDSRGKDLYVRPWGFARGTHKEQMVPRG
                     TPAEIAIETWEFESKLGRGRTCTLAVSSWPRFNPGASPASMKVFSNYHNGRLGNIDAQA
                     RGADWPVFLNGAGNVTESSGSCIALVKGGRLITPDLASGVLDSITRNTLFRLAEDELGL
                     SVETRPVERTELYLADEIFLMGTAAEVLPAVEVDGFPIGDGKTAGAITQALESCYHDTV
                     RAVTDKYDAWLTPVPAAPTR"
     misc_feature    152..29239
                     /note="miharamycins biosynthetic gene cluster"
     aSDomain        266..970
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mhr1_Aminotran_4.1"
                     /evalue="7.20E-34"
                     /label="mhr1_Aminotran_4.1"
                     /locus_tag="mhr1"
                     /protein_end="273"
                     /protein_start="38"
                     /score="109.4"
                     /tool="antismash"
                     /translation="FRFRDHMQRLLDSLRLGRLEPEFDADALVAAAAELLASWDSRGKD
                     LYVRPWGFARGTHKEQMVPRGTPAEIAIETWEFESKLGRGRTCTLAVSSWPRFNPGASP
                     ASMKVFSNYHNGRLGNIDAQARGADWPVFLNGAGNVTESSGSCIALVKGGRLITPDLAS
                     GVLDSITRNTLFRLAEDELGLSVETRPVERTELYLADEIFLMGTAAEVLPAVEVDGFPI
                     GDGKTAGAITQAL"
     gene            complement(1026..1322)
                     /gene="mhr2"
     CDS             complement(1026..1322)
                     /codon_start=1
                     /gene="mhr2"
                     /note="extradiol dioxygenase, alpha subunit"
                     /product="Mhr2"
                     /protein_id="QCX41906.1"
                     /transl_table=11
                     /translation="MSVQAIDRLCYDVAHDPETLERLRADPRRELGRRPLSAVERDELL
                     RGDVAALYRRGAHPVLLVRLANARVLGLDPGLYAARIRTAEARFSVSAPPGPA"
     gene            complement(1410..2234)
                     /gene="mhr3"
     CDS             complement(1410..2234)
                     /codon_start=1
                     /gene="mhr3"
                     /note="extradiol dioxygenase, beta subunit"
                     /product="Mhr3"
                     /protein_id="QCX41908.1"
                     /transl_table=11
                     /translation="MAEVVAVAGVPHTPVFPALARGDTESGAEVARRYAAVDEVVARAD
                     ADVLVVLTCDHINTFTPDMWPTFAVATGHSALGPNDDVPGVSPMSYALAADAGAALHRG
                     LVGQDFDPVALRDHSVDHSVVVPLHFLNGRRLPVVPVYVNGMVAPRPSAARCRRLGRVL
                     RNALEELPGRRVAVVASGSFSLEVGGPRVLPDQVYGVPRPAWARSVADRLHRGDLDGLV
                     AEATERRIEEAGTVAGEVLPWIAAAETAADLPLALMDHRDGEGHAFAAWGPA"
     gene            complement(2241..3266)
                     /gene="mhr4"
     CDS             complement(2241..3266)
                     /codon_start=1
                     /gene="mhr4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 210.1; E-value: 9e-64)"
                     /gene_kind="biosynthetic-additional"
                     /note="oxidoreductase"
                     /product="Mhr4"
                     /protein_id="QCX41909.1"
                     /transl_table=11
                     /translation="MLPDAELRWACDRDLARAESLARRYGLPRATADLRDVLADPEVDS
                     VSIAVDHAQHFELAAAALEAGKHVLVEKPLALTVEEGTALTALAQRTGRVLSVVSQHRY
                     DPVVTAVRDWIAGGLLGQLVSGTVSLQCGRDDAYYADSYWRGTFAGEGGSALVNQGYHA
                     LDVTRWLVGGLTVTGAAAGHTAPRGGMETEDTLAALLRGPQGALVTYHVTVASSITWRT
                     RVELVGTEGSVLFDLDHPGTLHLAEGGEALRAAAREVGAQVEPAPAGIGYYGISHRRQI
                     ADFAAAVRDGRRMTADGEAGLDTLRLLREMYGAARPGGPTAPGERTAVPAAANAVPALG
                     G"
     gene            3588..4424
                     /gene="mhr5a"
     CDS             3588..4424
                     /codon_start=1
                     /gene="mhr5a"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1204:transketolase (Score: 300.7; E-value: 3.9e-91)"
                     /gene_kind="biosynthetic-additional"
                     /note="transketolase, N-terminal domain"
                     /product="Mhr5a"
                     /protein_id="QCX41910.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 6.4e-11,
                     bitscore: 32.7, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-07, bitscore:
                     21.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYAPSSAPSSAGTHTDVVPHPDDLARRARRRVVELAARKAIHLGA
                     ALSMTDLLAVLYTRGLRYRPDRPDWPDRDLLVLSKGHGAYGLYAILAELGVIEADLASL
                     PGHPSDAVPGIEAATGALGHGLSLACGMALGARLAGRDQRVVVVTGDGELDEGSNWEAA
                     QFAAHHRLGNLVAVVDRNRLQQEGDTETVNALEPLADKWRAFGWRVTEADGHDTGAVTE
                     ALAALRAGDGPGVLIAHTVKGKGVPFAEGDPAWHMGELDAVQRATALAALARGERP"
     gene            4421..5368
                     /gene="mhr5b"
     CDS             4421..5368
                     /codon_start=1
                     /gene="mhr5b"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110:1-deoxy-D-xylulose-5-phosphate synthase (Score:
                     228.6; E-value: 1.3e-69)"
                     /gene_kind="biosynthetic-additional"
                     /note="transketolase, C-terminal domain"
                     /product="Mhr5b"
                     /protein_id="QCX41911.1"
                     /transl_table=11
                     /translation="MTGIARLGMRAALAPALADAVDADPALITLGADGQALFQGVMARH
                     PHRYVDVGIAEANLVGVAAGLARSGLRPVAAAMAPFLVRRAYEQLRLDVCVPGLPVVLL
                     GVGGGLGYGHLGPTHHATDDITLMSALPGMSVHCPADAADAVSVLRTVLSADGPAYIRL
                     SARPDPVLPPAASDGDPRTARLLRDGDDVLLLATGRCLAEALTAADALAADGVEAAVAS
                     VTTLHAFPRDAVRALARDRALVVTVAESLGPGGLGDRTALTLGRDGPPVVRLETDHRYP
                     PVASHEELLHFYGVDSRGIRSAVLGQLTRNTRKA"
     gene            5371..6627
                     /gene="mhr6"
     CDS             5371..6627
                     /codon_start=1
                     /gene="mhr6"
                     /note="cytosylglucuronic acid (CGA) synthase-type
                     glycosyltransferase"
                     /product="Mhr6"
                     /protein_id="QCX41912.1"
                     /transl_table=11
                     /translation="MRILSSAQACGFGPVSKLVAITPLLADGSVDFVGQDVALDFARRH
                     SHRFHRITEGDTRRYEDVAQSLADADLVVSVMDAELVFWAARADVPVLFFDSLLGFWLT
                     GRGSEELSARAQLVRWADPETARYVFDTLSPHERILLAHLLARRSFAQNFPGVPERIAA
                     LAEAGIDHIELCGPIVDRSALENALVLPPPERPAGLLINLGGFQNFFLDYESHNAYLDV
                     LRRWVAGLAAARPELGRILVCGGAFREPVTETHGAVEVEYAFLPQTEFLRHLAHTPLYA
                     VPPSLTSLHESVILRRLPLLLPEQHYGHIANLRALRGTVAGDTAASLTDLGSRFTVPED
                     DLEGTKALDRLTRELLTDESGYRHLAQHLDARLAAYQKLTAEERHAAVDELGDLLGGHA
                     LADLLQGVDADLVTAGRAS"
     gene            6624..7664
                     /gene="mhr7"
     CDS             6624..7664
                     /codon_start=1
                     /gene="mhr7"
                     /note="aminoglycoside-3'-phosphotransferase (APH)-type
                     O-kinase"
                     /product="Mhr7"
                     /protein_id="QCX41913.1"
                     /transl_table=11
                     /translation="MTHAPATCTSTRGTPAPADLADLTERTVDTDEVARLMLAAHLART
                     GTPEPAPDRVRSTTWTPAGARKIRRRTFVQLDIDGVPVAVAKVPLSTTDPKLARELEIL
                     RGFPAPAPLGSPVPLDALCGGFTMSHLPGVDLPTAVTGADGPDVLWQVLRPAVERVAEL
                     HLSADRVPSGPERALETAAAYVRNPEFGVEHADQALRTALLAPTHGDLGPWNVRYDARD
                     GSARVLDFEDYRATGIAAMDVVNLLVTTALPVFPDYPEHGFDWLYDQVFRTDHWFRSVL
                     ERGLAHYGSLTGQHPGRVLDLLPFTCQWLIERIEAEGRDTSGLFYRTFVERHLERRPAA
                     FGSDHA"
     gene            7657..9144
                     /gene="mhr8"
     CDS             7657..9144
                     /codon_start=1
                     /gene="mhr8"
                     /note="flavin-dependent oxidoreductase"
                     /product="Mhr8"
                     /protein_id="QCX41914.1"
                     /transl_table=11
                     /translation="MPEQTRTTSTDAVVIGGGPAGLFAALTLVRAGRRVALLEAGGDMR
                     ESLCSRLVARMDGRTVRDAEKFRLQCPRCTCLTGLGGAAFHFDTNLGYISSLTRSKIES
                     APDGTVRSYSGLERALGSFDRAQDLIGEAYRIFYELGLPPAGPPREDNGPLLGEGTVFQ
                     HVDTAYSQSVTVDDSLVVVARLKDELDSGGGSVLLHHRATDVEPLTGGGFEVRADTPHG
                     PAVFRADDVIVGVGKLGLPWVRDLARRIGVRHRPSSRVDLGVRLEADRADLAPLLDGCH
                     NPKLSFLNEEGHSVRTFCVCEGGRVMQYGFLDAVALDGQHCLNQPTTKSNLGILTTVDL
                     PEHIDGTEHAGEFAARVAAHGGGRPVVSTVDELAGRPAPEGPLTTSLINYHHGDLRDCL
                     PASIVRDVLAMVGRLNTLHPGLVPGTATVAAPVVERLFPDLDLSDDLESSVPGLYFVGD
                     SSSKIIGITYGAATGMAAARSVLHRRVTTAAAAGGRH"
     gene            9144..11582
                     /gene="mhr9"
     CDS             9144..11582
                     /NRPS_PKS="Domain: AMP-binding (198-593). E-value: 1.9e-86.
                     Score: 282.1. Matches aSDomain:
                     nrpspksdomains_mhr9_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (706-771). E-value: 3.7e-16. Score:
                     51.0. Matches aSDomain: nrpspksdomains_mhr9_PCP.1"
                     /codon_start=1
                     /gene="mhr9"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     344.8; E-value: 1.2e-104)"
                     /gene_kind="biosynthetic"
                     /note="PKS loading module (adenylation-thiolation)"
                     /product="Mhr9"
                     /protein_id="QCX41915.1"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-92, bitscore:
                     300.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.8e-14, bitscore:
                     44.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLPQRLPTATPPRPERTSARLTAPAARLLGAPEGHRVLAALSR
                     LLLHRYGAGWEVFGTSGDTLVRHACADDQETPTLAELTGATRPVAADLPVDGEPYVAVL
                     ADSPAVPPAVLGRPVWTAAADGPALRLTHDAAVVDAATAGRVAEHLALLAHHTAVRPRT
                     TAGEVDLLLPDERTLLLDTWNAPHTVHADTTLHRMFREQAARTPDAIALRDGGTEVTYG
                     ELDADSDRFARRLRPYVTEPGALVVLSGDRDTALFTAVLGIWKAGGGFVHLDPHLPDLR
                     VEEILGLVDPVAVLTTGSGHRAVAGRSLPVADLLDPAAPPAAPPGAPEDRARPDNTAYV
                     LFTSGSTGTPKGVVRPHRMHTSRIRLEQGMYGMGRDDRHLLKSPISFREFAWPLATGGT
                     AVLAAPGKDRDDRYLAELIRDERITTVSFVPSMLRLLLTQPAFRTAPALRHVFVGGEAL
                     GQDLEDELRGLGLAVHNTYTLSEADYVCHRTGPLPEPRPARTGTVVGVPLDMRIYLCDA
                     AGRLVPPGVVGEINTAGPGLADGYLNRPDLTAERFRPNHLDPAGPPVLFRTGDLARHLP
                     DGQVEYVGRADDQVKVRGQRVEPTEVETVLRGHPGVANAAVVGIPDPDQGAVLVAYVVP
                     DGEEVPPQRLREHLAARLPDFMVPAHVASTPALPLLPSGKVDRKALRVTPRTRPALDVP
                     YTPPATPGQERAAALVARVLGLDTVGVDDDFFALGGDSLRLMLLRGSLESACGREFALA
                     DVFAARTPRGYARLLEDTDGTADADSLRRPSERRRPPPRRTAASATRTRTRSSEGGEPR
                     "
     aSDomain        9738..10922
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mhr9_AMP-binding.1"
                     /evalue="1.90E-86"
                     /label="mhr9_AMP-binding.1"
                     /locus_tag="mhr9"
                     /protein_end="593"
                     /protein_start="198"
                     /score="282.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FREQAARTPDAIALRDGGTEVTYGELDADSDRFARRLRPYVTEPG
                     ALVVLSGDRDTALFTAVLGIWKAGGGFVHLDPHLPDLRVEEILGLVDPVAVLTTGSGHR
                     AVAGRSLPVADLLDPAAPPAAPPGAPEDRARPDNTAYVLFTSGSTGTPKGVVRPHRMHT
                     SRIRLEQGMYGMGRDDRHLLKSPISFREFAWPLATGGTAVLAAPGKDRDDRYLAELIRD
                     ERITTVSFVPSMLRLLLTQPAFRTAPALRHVFVGGEALGQDLEDELRGLGLAVHNTYTL
                     SEADYVCHRTGPLPEPRPARTGTVVGVPLDMRIYLCDAAGRLVPPGVVGEINTAGPGLA
                     DGYLNRPDLTAERFRPNHLDPAGPPVLFRTGDLARHLPDGQVEYVGRADDQVKVR"
     aSModule        9738..11456
                     /complete
                     /domains="nrpspksdomains_mhr9_AMP-binding.1"
                     /domains="nrpspksdomains_mhr9_PCP.1"
                     /locus_tags="mhr9"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9924..9965
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr9_0001"
                     /evalue="1.30E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="mhr9"
                     /protein_end="274"
                     /protein_start="260"
                     /score="12.3"
                     /tool="antismash"
                     /translation="LGIWKAGGGFVHLD"
     CDS_motif       10155..10214
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr9_0002"
                     /evalue="2.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="mhr9"
                     /protein_end="357"
                     /protein_start="337"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AYVLFTSGSTGTPKGVVRPH"
     CDS_motif       10710..10799
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr9_0003"
                     /evalue="1.70E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="mhr9"
                     /protein_end="552"
                     /protein_start="522"
                     /score="49.0"
                     /tool="antismash"
                     /translation="PPGVVGEINTAGPGLADGYLNRPDLTAERF"
     CDS_motif       10887..10952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr9_0004"
                     /evalue="7.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="mhr9"
                     /protein_end="603"
                     /protein_start="581"
                     /score="37.2"
                     /tool="antismash"
                     /translation="YVGRADDQVKVRGQRVEPTEVE"
     aSDomain        11262..11456
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mhr9_PCP.1"
                     /evalue="3.70E-16"
                     /label="mhr9_PCP.1"
                     /locus_tag="mhr9"
                     /protein_end="771"
                     /protein_start="706"
                     /score="51.0"
                     /tool="antismash"
                     /translation="AALVARVLGLDTVGVDDDFFALGGDSLRLMLLRGSLESACGREFA
                     LADVFAARTPRGYARLLEDT"
     gene            11579..14665
                     /gene="mhr10"
     CDS             11579..14665
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (19-429). E-value:
                     2.9e-118. Score: 387.2. Matches aSDomain:
                     nrpspksdomains_mhr10_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (526-814). E-value: 8.7e-62.
                     Score: 201.0. Matches aSDomain:
                     nrpspksdomains_mhr10_PKS_AT.1"
                     /NRPS_PKS="Domain: PCP (943-1006). E-value: 1.5e-13. Score:
                     42.7. Matches aSDomain: nrpspksdomains_mhr10_PCP.1"
                     /codon_start=1
                     /gene="mhr10"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 102.1; E-value:
                     4.6e-31)"
                     /gene_kind="biosynthetic"
                     /note="PKS (acyltransferase-ketosynthase-thiolase)"
                     /product="Mhr10"
                     /protein_id="QCX41916.1"
                     /sec_met_domain="PKS_KS (E-value: 1.4e-118, bitscore:
                     387.2, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.2e-62, bitscore: 201.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.6e-12, bitscore:
                     36.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAPLPGPPAPSADHDEWAVAVVGMAVRLPGCDSLDRYWEILDSG
                     EDSVTRRERTSGSFVPAYGSVPRPAHFDPARFGIAHSEALLLDPQHRLLLEAADEALEA
                     ANVDRVRTPGISVYAGVGHNEYERWVGTALAGRPGVDAQALEVTNRGDYAATRVAYRLG
                     LQGAAVTVQSACSTALTAVHLAAQDLLSHGSSLAVAGVASVRVPAPGGYEAPLGGIGSP
                     DGVCRPFDRAAGGSVPGDGAGAVVLKRLADALRDGDDIWAVVRGTAMNNDGSGKSGFAG
                     VDPAAQAEVIRAALDVAGLEPDDIDYVEAHGSGTRIGDASEWTALHEVFGGVRHRVHVG
                     AVKAGLGHLREAAGLAGLVKAVLSLRHGRLVATPHFERLPSDLARREGPLAPLGEALDW
                     PAAGHRPRRAGVSAFGLGGTNCHIVLEEAPPRARDAAAATGEAELVLLSSHHPDALTAD
                     LDAVRDHLERNPARTGDTAWTTQTARHRHPHRAYAVVTPAAGTEAAFAADRLRVQQGRA
                     PADAPEVVFVLPGIGSHYLGMGADLARTDPLFAGHLRAAVTVADQLTDGAVGRSFASGQ
                     ERSSGDGNRVDLRAMLRRDGATPSPRRQLRDVHLSLFCLEHAMARTLMDLGIRPAALLG
                     HSLGEWVAAVLAGVIGLDDAMAAVARRADLVVTAGEGAMLGVLAAADDVEKYALDDTWL
                     AADNGPGHCVFSGRPAAISALADRLRGDGFTVLPVDTAHPFHTPQLTRAADLLGEDLRE
                     VRLHPARIPIASSVLGSWLDGGIPQPSYWRDHMVGRVRFRTAAGLVLDRHRVLIEVGPG
                     TTRPWIGQTAPDAVCVRTVRQSYEHVPDRQILLEALGELWTHGVEADWQRLHPAPGRRT
                     TLPPRNLVRRRFLPDSAPPADPWPGTASAPPADAPLPAGRDDTAEHERTPVAGGAAPST
                     VSGPAAPSTVSGFLAERFRVLLGLREVHPDDHFFHLGGDSLMGVHLISGLKQLTGRSVP
                     SSVVFASATLGGMTREVENWLATPAPQQPEPSENGSRTP"
     aSDomain        11636..12865
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mhr10_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="2.90E-118"
                     /label="mhr10_PKS_KS.1"
                     /locus_tag="mhr10"
                     /protein_end="429"
                     /protein_start="19"
                     /score="387.2"
                     /tool="antismash"
                     /translation="VAVVGMAVRLPGCDSLDRYWEILDSGEDSVTRRERTSGSFVPAYG
                     SVPRPAHFDPARFGIAHSEALLLDPQHRLLLEAADEALEAANVDRVRTPGISVYAGVGH
                     NEYERWVGTALAGRPGVDAQALEVTNRGDYAATRVAYRLGLQGAAVTVQSACSTALTAV
                     HLAAQDLLSHGSSLAVAGVASVRVPAPGGYEAPLGGIGSPDGVCRPFDRAAGGSVPGDG
                     AGAVVLKRLADALRDGDDIWAVVRGTAMNNDGSGKSGFAGVDPAAQAEVIRAALDVAGL
                     EPDDIDYVEAHGSGTRIGDASEWTALHEVFGGVRHRVHVGAVKAGLGHLREAAGLAGLV
                     KAVLSLRHGRLVATPHFERLPSDLARREGPLAPLGEALDWPAAGHRPRRAGVSAFGLGG
                     TNCHIVLEEAP"
     aSModule        11636..14596
                     /complete
                     /domains="nrpspksdomains_mhr10_PKS_KS.1"
                     /domains="nrpspksdomains_mhr10_PKS_AT.1"
                     /domains="nrpspksdomains_mhr10_PCP.1"
                     /locus_tags="mhr10"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       11660..11683
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr10_0001"
                     /evalue="1.20E+01"
                     /label="PCP_mC"
                     /locus_tag="mhr10"
                     /protein_end="35"
                     /protein_start="27"
                     /score="0.4"
                     /tool="antismash"
                     /translation="RLPGCDSL"
     CDS_motif       12023..12088
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr10_0002"
                     /evalue="7.30E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="mhr10"
                     /protein_end="170"
                     /protein_start="148"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="NRGDYAATRVAYRLGLQGAAVT"
     CDS_motif       12074..12121
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr10_0003"
                     /evalue="8.60E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="mhr10"
                     /protein_end="181"
                     /protein_start="165"
                     /score="9.0"
                     /tool="antismash"
                     /translation="GAAVTVQSACSTALTA"
     CDS_motif       12497..12544
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr10_0004"
                     /evalue="2.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="mhr10"
                     /protein_end="322"
                     /protein_start="306"
                     /score="10.7"
                     /tool="antismash"
                     /translation="YVEAHGSGTRIGDASE"
     CDS_motif       12815..12832
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr10_0005"
                     /evalue="9.90E+01"
                     /label="PCP_mC"
                     /locus_tag="mhr10"
                     /protein_end="418"
                     /protein_start="412"
                     /score="-3.3"
                     /tool="antismash"
                     /translation="AFGLGG"
     CDS_motif       13151..13204
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr10_0006"
                     /evalue="2.00E-03"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="mhr10"
                     /protein_end="542"
                     /protein_start="524"
                     /score="11.0"
                     /tool="antismash"
                     /translation="VFVLPGIGSHYLGMGADL"
     aSDomain        13157..14020
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mhr10_PKS_AT.1"
                     /evalue="8.70E-62"
                     /label="mhr10_PKS_AT.1"
                     /locus_tag="mhr10"
                     /protein_end="814"
                     /protein_start="526"
                     /score="201.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VLPGIGSHYLGMGADLARTDPLFAGHLRAAVTVADQLTDGAVGRS
                     FASGQERSSGDGNRVDLRAMLRRDGATPSPRRQLRDVHLSLFCLEHAMARTLMDLGIRP
                     AALLGHSLGEWVAAVLAGVIGLDDAMAAVARRADLVVTAGEGAMLGVLAAADDVEKYAL
                     DDTWLAADNGPGHCVFSGRPAAISALADRLRGDGFTVLPVDTAHPFHTPQLTRAADLLG
                     EDLREVRLHPARIPIASSVLGSWLDGGIPQPSYWRDHMVGRVRFRTAAGLVLDRHRVLI
                     EVGPGTT"
     CDS_motif       13457..13573
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr10_0007"
                     /evalue="6.70E-19"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="mhr10"
                     /protein_end="665"
                     /protein_start="626"
                     /score="60.1"
                     /tool="antismash"
                     /translation="GIRPAALLGHSLGEWVAAVLAGVIGLDDAMAAVARRADL"
     CDS_motif       13661..13699
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr10_0008"
                     /evalue="1.70E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="mhr10"
                     /protein_end="707"
                     /protein_start="694"
                     /score="14.7"
                     /tool="antismash"
                     /translation="AADNGPGHCVFSG"
     aSDomain        14408..14596
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mhr10_PCP.1"
                     /evalue="1.50E-13"
                     /label="mhr10_PCP.1"
                     /locus_tag="mhr10"
                     /protein_end="1006"
                     /protein_start="943"
                     /score="42.7"
                     /tool="antismash"
                     /translation="LAERFRVLLGLREVHPDDHFFHLGGDSLMGVHLISGLKQLTGRSV
                     PSSVVFASATLGGMTREV"
     CDS_motif       14462..14491
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr10_0009"
                     /evalue="2.00E-02"
                     /label="PCP_mC"
                     /locus_tag="mhr10"
                     /protein_end="971"
                     /protein_start="961"
                     /score="8.5"
                     /tool="antismash"
                     /translation="HFFHLGGDSL"
     gene            14662..15507
                     /gene="mhr11"
     CDS             14662..15507
                     /codon_start=1
                     /gene="mhr11"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095:3-hydroxybutyryl-CoA dehydrogenase (Score: 284.4;
                     E-value: 1.4e-86)"
                     /gene_kind="biosynthetic-additional"
                     /note="dehydrogenase; FkbK-like"
                     /product="Mhr11"
                     /protein_id="QCX41917.1"
                     /transl_table=11
                     /translation="MTAPTIGVLGAGVIGSSVAHAAAAAGYTVTLVDSDAAALDTARTT
                     IRRHQRLATLLGGGRSAHALDIRPSTDLAALADAELVVENTTESEEAKRALYPALEDVI
                     APDTTIAANTSAVPIGRLAERLADPGRVVGVHFMNPVDRIDMVEVVRGKASSDAAMAAV
                     DTLLRRMGKKAVVVEDAPGFVINRVLMPVVNLAAAVVADGVATPSQVDELFKGCLGHTS
                     GPLRTADLIGLDTVVRTLEVLHDHYGTGEFVTHPALRRMVDQGLLGTKSGRGFYSYDGN
                     "
     gene            15511..15804
                     /gene="mhr12"
     CDS             15511..15804
                     /NRPS_PKS="Domain: PP-binding (22-90). E-value: 1.1e-08.
                     Score: 27.3. Matches aSDomain:
                     nrpspksdomains_mhr12_PP-binding.1"
                     /codon_start=1
                     /gene="mhr12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147:putative acyl carrier protein (Score: 72.9;
                     E-value: 2.5e-22)"
                     /gene_kind="biosynthetic-additional"
                     /note="acyl carrier protein; FkbJ-like"
                     /product="Mhr12"
                     /protein_id="QCX41918.1"
                     /sec_met_domain="PP-binding (E-value: 5.5e-09, bitscore:
                     27.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASQPTTATPAPSTAPAAHEVTDAVRQFIARLSGHPDIADDRPLI
                     SDGVLDSVAAVQMVDFVERTFAIEIADEDLELANFDSVQGLAALVHRRLAAS"
     aSDomain        15577..15780
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mhr12_PP-binding.1"
                     /evalue="1.10E-08"
                     /label="mhr12_PP-binding.1"
                     /locus_tag="mhr12"
                     /protein_end="90"
                     /protein_start="22"
                     /score="27.3"
                     /tool="antismash"
                     /translation="DAVRQFIARLSGHPDIADDRPLISDGVLDSVAAVQMVDFVERTFA
                     IEIADEDLELANFDSVQGLAALV"
     gene            15801..16985
                     /gene="mhr13"
     CDS             15801..16985
                     /codon_start=1
                     /gene="mhr13"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 270.8; E-value:
                     3.2e-82)"
                     /gene_kind="biosynthetic-additional"
                     /note="dehydrogenase; FkbI-like"
                     /product="Mhr13"
                     /protein_id="QCX41919.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.4e-14, bitscore:
                     45.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.8e-17, bitscore:
                     54.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1e-28, bitscore:
                     91.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESAPEALLQALRDDAFAARATAWERAGAVPREDIDALAALGLL
                     GLTVDTAHKGSGTPAAAVTEVHRLVAAASPSLHSLLVVHAMVCHAVQRWAGPELRDTLL
                     PELATGRTLAAFALTEEEAGADFGNLTTTIEEDGGSLRVTGTKRWLSFGRIADTYLVFG
                     TTAGRGSCALVDAGPGVRISAEPVTAGLRAARLARVTFDGATAPATRAIARPGFGVPFV
                     ATSCLTLGRLYVAAGAVGVAEAALALATRHAATRTHGGTTLGERQLVRGLLADAALATD
                     AAARYVRQTAHEVADREPSAVVTAARAKLLATRAASLTTATASRLLGAAGQTEDHPLAR
                     LHAAARVHEVIEGPTEVLQDIVAADLLRGRAAADGARPATDGARPGKDHAHADR"
     gene            16972..18108
                     /gene="mhr14"
     CDS             16972..18108
                     /NRPS_PKS="Domain: FkbH (14-132). E-value: 1.6e-17. Score:
                     55.6. Matches aSDomain: nrpspksdomains_mhr14_FkbH.1"
                     /codon_start=1
                     /gene="mhr14"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1256:FkbH like protein (Score: 385.2; E-value:
                     3.5e-117)"
                     /gene_kind="biosynthetic-additional"
                     /note="glyceryl-S-acyl carrier protein synthase; FkbH-like"
                     /product="Mhr14"
                     /protein_id="QCX41920.1"
                     /transl_table=11
                     /translation="MPTADPRTAPAPQVKCVVWDLDETLWDGTLLEGDDLSVPEANRKL
                     IRTLDEHGILQSVASRNDPDAVTEQLRAFGLAEYFLYPQVGWSAKSASLRAVTRELNIA
                     PDSVLFVDDSEFERAEVASELPEVRCMTRQELHARVADGAVLPAHVTDDARHRRELYLA
                     ESRRRSHEGAFDGPAEEFLHSLGMTLHVREATAGDLARAAELTQRTHQLNTTGITFDQD
                     ELASLMSDPGHRVLVAELDDRFGTYGTIGLAVLATGHPDTSADREAGATRRWTIRLLLM
                     SCRVMGRNVGTTLIAAVSRLATAHGAATVAHFRPTDRNRQMLLTYRFAGFTVESRTEDL
                     VVLTLPDELRPAVPGYVRLVLDDTAAASPRGTTQELTA"
     aSDomain        17014..17367
                     /aSDomain="FkbH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mhr14_FkbH.1"
                     /evalue="1.60E-17"
                     /label="mhr14_FkbH.1"
                     /locus_tag="mhr14"
                     /protein_end="132"
                     /protein_start="14"
                     /score="55.6"
                     /tool="antismash"
                     /translation="KCVVWDLDETLWDGTLLEGDDLSVPEANRKLIRTLDEHGILQSVA
                     SRNDPDAVTEQLRAFGLAEYFLYPQVGWSAKSASLRAVTRELNIAPDSVLFVDDSEFER
                     AEVASELPEVRCMT"
     gene            18105..18728
                     /gene="mhr15"
     CDS             18105..18728
                     /codon_start=1
                     /gene="mhr15"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 99.4; E-value:
                     3.9e-30)"
                     /gene_kind="biosynthetic-additional"
                     /note="methyltransferase"
                     /product="Mhr15"
                     /protein_id="QCX41921.1"
                     /transl_table=11
                     /translation="MKAFTQSWTDTFSSVYSEEPLAKLSWFNASPGLELIKRVIDGTLK
                     PGQRLIDLGSGPGVDAVFLSVQGLDVTGVDLSADAVVRARRWAELAGASADFIQGDVLD
                     VPLPDHSADVVTDSFVFHNMRDEAREPYADEVHRLLKPGGLFLLNSFSDHMVEGTGPRR
                     ITSEEILGTFRSDRFECVGLYVYRNVPTRTKPDQLHWFGEFRAR"
     gene            18728..19462
                     /gene="mhr16"
     CDS             18728..19462
                     /NRPS_PKS="Domain: PKS_KR (2-154). E-value: 1.1e-16. Score:
                     53.1. Matches aSDomain: nrpspksdomains_mhr16_PKS_KR.1"
                     /codon_start=1
                     /gene="mhr16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     228.9; E-value: 1.1e-69)"
                     /gene_kind="biosynthetic-additional"
                     /note="oxidoreductase"
                     /product="Mhr16"
                     /protein_id="QCX41922.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-37, bitscore:
                     119.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVVTGGGRGIGRAVALGFAERGARVALLARTASQVRSVADEIE
                     ALGAESLALTADVADEKQVLRCAEQVTETFGGLDVLVNAAGVFDLGPTTEFPAEDARGL
                     LATNVMGTFLTCKVFGRQLLDQGHGKVVNFCSLLSYTAFPERALYAASKGGVLQLTRSL
                     GVEWAARGVNVNAVAPGMIRIETPHPAALAEDAIVGRIPARRRGSPRDIVGPVLFLASP
                     EADYINGQTLVVDGGWLSYGYL"
     aSDomain        18734..19189
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_mhr16_PKS_KR.1"
                     /evalue="1.10E-16"
                     /label="mhr16_PKS_KR.1"
                     /locus_tag="mhr16"
                     /protein_end="154"
                     /protein_start="2"
                     /score="53.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVVTGGGRGIGRAVALGFAERGARVALLARTASQVRSVADEIEAL
                     GAESLALTADVADEKQVLRCAEQVTETFGGLDVLVNAAGVFDLGPTTEFPAEDARGLLA
                     TNVMGTFLTCKVFGRQLLDQGHGKVVNFCSLLSYTAFPERALYAASKG"
     CDS_motif       18737..18826
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr16_0001"
                     /evalue="5.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="mhr16"
                     /protein_end="33"
                     /protein_start="3"
                     /score="19.2"
                     /tool="antismash"
                     /translation="VVTGGGRGIGRAVALGFAERGARVALLART"
     CDS_motif       18842..18892
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr16_0002"
                     /evalue="4.00E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="mhr16"
                     /protein_end="55"
                     /protein_start="38"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="SVADEIEALGAESLALT"
     CDS_motif       19088..19234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_mhr16_0003"
                     /evalue="5.10E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="mhr16"
                     /protein_end="169"
                     /protein_start="120"
                     /score="-3.3"
                     /tool="antismash"
                     /translation="RQLLDQGHGKVVNFCSLLSYTAFPERALYAASKGGVLQLTRSLGV
                     EWAA"
     gene            19449..20042
                     /gene="mhr17"
     CDS             19449..20042
                     /codon_start=1
                     /gene="mhr17"
                     /note="phosphoribohydrolase; LOG-1-like"
                     /product="Mhr17"
                     /protein_id="QCX41923.1"
                     /transl_table=11
                     /translation="MDTSEHPLSIGVFCGASAGRSPRYAEVAAELGTRIAARGHRLVYG
                     AGGVGMMGEVARAAAAGGAPILGVIPEFLRTREMGDELPPQELVLTTDLLQRKRIMIDS
                     ADAFVALPGGYGTLDEILEVVSMAALGQRVGPLVLVDVEGDWDPLRRLVEGLLRRGFVR
                     DAGLVRVAADPDQALDLVAAARTGALAGAFDAGV"
     gene            20064..21338
                     /gene="mhr18"
     CDS             20064..21338
                     /codon_start=1
                     /gene="mhr18"
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 112; E-value: 4e-34)"
                     /gene_kind="transport"
                     /note="membrane protein"
                     /product="Mhr18"
                     /protein_id="QCX41924.1"
                     /transl_table=11
                     /translation="MKTAARREPLPRYAGFLTGWGATTFGTGLVLPLTVVYLRETLGLP
                     TSGVSLYFALFALAGLAVNPLAGRAGKVYGPGLAAIGATVLQAAGAAWLTAAGSMAATV
                     PAACLSGAGTGAYYAVQTPLLTKAFGNARLSRVLSGQHRVSALTMAVGALLGGQAVERL
                     GERGYTWCLAVNAVSYLVHGAMLARLPRARLRPAGSGVDGAGPDLPHGVRDGRSAALHD
                     TVFLRLLLVQTALVVFGIAQVDAVVPAILRNADLSVSAVSVVIACNTVGVIVFQGLALR
                     VVERIGYVAALTAAIVVWVAAMAALTAAVLMPGLRLRLLLGSLFGLLFAIGECLIAPSV
                     QPLVTLTAPAGRLEGYAAATSLAHGLGAFVSPLVLLPVVDGGGVWSYLALQLGGYGLAL
                     YALLSFRARSVRRLASSPLSEETTP"
     gene            21605..22165
                     /gene="mhr19"
     CDS             21605..22165
                     /codon_start=1
                     /gene="mhr19"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 116.1;
                     E-value: 2.3e-35)"
                     /gene_kind="biosynthetic-additional"
                     /note="4'-phosphopantetheinyl transferase"
                     /product="Mhr19"
                     /protein_id="QCX41925.1"
                     /transl_table=11
                     /translation="MEPGEVRLTREICGLPHCARPHGRPVLSGASPPVQFSLSRSGDLA
                     VVALATVPVGVDVESRAFRHPDSPLDGMIRRLHPAERAALARLPPAQREEGFLSCWVRK
                     EAYLKGTGTGLPGGLARHCVGLAAELAPGGRGPAPTPRGWTFLDLDLPPGHRAALAVAQ
                     VIRGNFPTLFHLTPREISDSLND"
     misc_feature    22127..22129
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            22230..23468
                     /gene="mhr20"
     CDS             22230..23468
                     /codon_start=1
                     /gene="mhr20"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 66.4; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /note="ATP-grasp ligase"
                     /product="Mhr20"
                     /protein_id="QCX41926.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4.3e-11,
                     bitscore: 33.5, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 9.6e-10, bitscore:
                     29.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHDSAGRRETLLVVGSGYRAGHERLLAQMAADADLILLNPEPVS
                     WQRDWVQAAEVFDPADGDDGVLRTAKTLVDRRPVAAVVTYEETMVVTTARLAQSLGLPG
                     VPVAAAELARDKHRQRTLLNSTGISPTRSVLVHDLPAARRAAQEIGYPLMVKPRGLSGS
                     AGVRRVDEESQFDAAFDAAVNADKRGLESEGVLVEEFLEGFEFDVDCLVHDGTATPVSW
                     ARKIWAYDPYPIEAGFITGHGTLGRAEMTEGFDLACRSVLAAGIDRTVAHVEVKMTPAG
                     PRIIELNARPGGDIASRIVELARGVRLGSLLVSAALGRAPHTASSDDRSAGIRFLYPRS
                     RRRFDGLAEAARLRSRPWVHEIRELHPRGETVAPPPEDLYGRVGYVMATGPHADEVEDR
                     LLLAHHELRVLGS"
     gene            23540..24271
                     /gene="mhr21"
     CDS             23540..24271
                     /codon_start=1
                     /gene="mhr21"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 72.5; E-value:
                     6.2e-22)"
                     /gene_kind="biosynthetic-additional"
                     /note="methyltransferase"
                     /product="Mhr21"
                     /protein_id="QCX41927.1"
                     /transl_table=11
                     /translation="MTEWKPETYGPRWKNVYDHIDWPQPEGAVEFLAKRAGSGRALELA
                     IGTGRVAIPLARLGVPLDGLDASPEIVEVMRGKPGGESIEVSIGNIADFTSERRYSLIF
                     LLLNSLYALQTQEEQIQCFESVAAHLEPGGLFVVETFVPDPTRFHFNGRAHVYDVGLDH
                     VRIEADTFDRATQHIKENHIEIREDGIRLYPAFLRYTWPSELDLMARIAGLELSERWGD
                     WGNVPYDTYSENHIGVYRKAS"
     gene            24276..25121
                     /gene="mhr22"
     CDS             24276..25121
                     /codon_start=1
                     /gene="mhr22"
                     /note="phenylalanine-tRNA synthetase, alpha subunit"
                     /product="Mhr22"
                     /protein_id="QCX41928.1"
                     /transl_table=11
                     /translation="MPDGLAPTVLTPAVADARCDPGLPPAGPRTGRPHPVAALVDRIGD
                     LFVPLGFDLVQLPLLESVRDNFDVLGYPPDHPTRTRLSLLPAPDVVLRTHATSGGPRAM
                     RAAAPGPLRALLVGTCFRNELSSPYSGSQFTQIDGLVVQPDVGLPELMGLFDRLVSGLF
                     GPGHPWRVRRGGYPFAAPGFAVEVACPRCGPGCDECEGRGHVEIGAGGLLRAQVLTAGG
                     YDPHRVTGLSFGCSVERLLRLSHGLTDIRELLVNDMRLLEQFEHAYLPVGPSEKGVDRP
                     "
     gene            25118..27127
                     /gene="mhr23"
     CDS             25118..27127
                     /codon_start=1
                     /gene="mhr23"
                     /note="phenylalanine-tRNA synthetase, beta subunit"
                     /product="Mhr23"
                     /protein_id="QCX41929.1"
                     /transl_table=11
                     /translation="MRIPLAWLERECGGPVDPEELLDGLRASGARAALADARAVDVEPP
                     PELAHLASVRGLAAEIRARHGGTPSPPARSPRLADGLAMTADEQVPGRVAAAVVRLPGP
                     VRLPADAADRLRAAGVRLTGTVADLIAYVALETGQPLGAADARTLDLTALRLRTVSTTE
                     SVTHRLPSGPRPLPPGTWVLSAGDETPAVLGWDPPPEPVPADGRETLVWAWWLAPEAAR
                     RADGAGPEPDAVAERGVRGHDPETPDRAVARLGELVTEWAGGTVSAAGRAGRPAPAPRV
                     LRVDAGELCRLVDPELDRTTVTALLTAGEAAVRAEGDLLYVTVGAGRPDLDCVAALAGD
                     AARVRGYRTVPRRLPPSSAGPWPDPERLLRDALTTTALRRGLQQVVTPVLLRSSEPLTR
                     LGVAPGAEPIAVRGRAGLRDMRVRGSLLPGLLGVAGRSLHQTGAAQVFELGQVPLSATP
                     HDETWRFAVVLSGASTPASLVEPRPRTVGFADLTGLLRAAAGAVGQEAPELTPQPYAGF
                     VAGASFAVRLQGGTVGRAGLLSEENATLLDAPGERLFCAELDLTALGGLPPVPVAVRVP
                     EPLPLPAFNVTVVVPEAVSAGDVLRVVAEAGRTERARVTVKDLLRGGRVPAGQLSLTVR
                     AEFAGADAGPVREERRRRREAVLRALGDRGWSGQ"
     gene            27124..27813
                     /gene="mhr24"
     CDS             27124..27813
                     /codon_start=1
                     /gene="mhr24"
                     /note="YqcI/YcgG/DcsA-type N-hydroxylase"
                     /product="Mhr24"
                     /protein_id="QCX41930.1"
                     /transl_table=11
                     /translation="MTGPTTPGHEGAEDAVELFTEWLRSDGFTCLGARAALHRGELVTG
                     VYPALASAECLPELASDLGRFITGPLSTDGRFHSFAAIFTECDPPDPDEETFEQLLWRQ
                     LRALHEADRTDNVWAHDVSDDPRSPDFGFSFGGHPFFVIGLHPGASRVSRRFARPALVF
                     NSHRQFAELKRAGVYQGMQTKIRAKERELQGDVNPMLAEHGVISEARQYSGRIVPPDWE
                     CPFSRPG"
     gene            complement(27797..28495)
                     /gene="mhr25"
     CDS             complement(27797..28495)
                     /codon_start=1
                     /gene="mhr25"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 55.8; E-value: 1.3e-16)"
                     /gene_kind="regulatory"
                     /note="tetR-type transcriptional regulator"
                     /product="Mhr25"
                     /protein_id="QCX41931.1"
                     /transl_table=11
                     /translation="MGEPTTDTGRAGGGVTPLRRTPRQARSKARLARVLEAAERVLVSE
                     GVEALTTTRVAAEAQVSVGSLYQYLPDRDAIIDALAGGYFARLEAVMEDFARAAADENW
                     DDPVGVLIDACAAVYRTEHGFRALWFGSGLTERTRAADREHKRQMADGVRRVLLALGLA
                     EDDEALGRACHAAFLAADALAQEAFRRDPEGDAALLGEAKTMLRGYLVEVTGRYRRPAR
                     AATADVSRAD"
     gene            28553..29239
                     /gene="mhr26"
     CDS             28553..29239
                     /codon_start=1
                     /gene="mhr26"
                     /note="epimerase/aldolase"
                     /product="Mhr26"
                     /protein_id="QCX41932.1"
                     /transl_table=11
                     /translation="MTDSSSALGLERAAVADACRRLGAAGLLIGTAGNVSVRVGERVAV
                     TATGAVLAQLTAGQVSVVDLDGKVVAGTLRPTSELELHLGVYRRYGAGAVVHTHAPMAT
                     ALSCVLDELPCIHYQLLALGGSVRVAPYATFGTPELAESVLGALEGRSAALMASHGALT
                     HGPTLDKAVEHALLLEWACGVYQHAAALGTPRVLDEQQQRAVIEAAIVRNYGTTQSVPP
                     AQEGNR"
ORIGIN
        1 gactgcgttt gtgactgcct tgacagagat tccttgctga acctagggtc ggtcagggtt
       61 ctgcgtgatc tccaggttca gtagggttcc gtcgagagga gcaggcgtgt cttccgaata
      121 tggacgcttg atatggcgca atggcgcttt catgccatgg gaagaggcga cgatccacat
      181 cagttccgtg gggcacgcct cggtctccgc cgcgttcgaa ggcgtccact cctactggag
      241 cgaaacgcgc ggggcgctgt acggcttccg gttccgcgac cacatgcagc ggttgctgga
      301 ctccctgcgg ctgggccgcc tggagcccga gttcgacgcc gacgcgctcg tcgcggccgc
      361 cgccgaactg ctcgcttcgt gggacagccg gggcaaggac ctctatgtgc gtccgtgggg
      421 cttcgcccgg gggacgcaca aggaacagat ggtgccgcgc gggacgccgg cggaaatcgc
      481 catcgagacc tgggagttcg agagcaaact cggccggggg cgcacctgca ccctcgcggt
      541 cagttcctgg ccccgcttca accccggtgc ctcaccggct tcgatgaagg tgttctcgaa
      601 ctaccacaac ggcaggctgg gcaatatcga cgcacaggcc cgcggcgccg actggccggt
      661 cttcctcaac ggcgcgggga acgtcaccga gtcctccggc tcgtgcatcg ccctggtcaa
      721 gggcggccgg ctcatcaccc ccgacctggc cagcggggtt ctggacagca tcacccgcaa
      781 caccctgttc cggcttgccg aggacgaact cggcctgtcc gtcgagaccc ggcccgtgga
      841 gcggaccgag ctgtatctcg ccgacgagat cttcctcatg ggcacggcgg ccgaagtgct
      901 gcccgccgtc gaggtcgacg ggttccccat cggtgacggc aagaccgccg gcgcgatcac
      961 gcaggcgctg gagtcctgct accacgacac ggtccgcgcc gtcaccgaca agtacgacgc
     1021 ctggctcacg ccggtcccgg cggcgccgac acgctgaagc gcgcctcggc cgtccggatg
     1081 cgcgccgcgt agagccccgg atcgaggccc agcacacggg cgttggccag ccgtaccagc
     1141 agaaccggat gcgccccccg gcggtagagg gcggcgacgt cgccgcgcag cagttcgtcc
     1201 cgctccaccg cggacagcgg gcgacgcccc agctcccgcc gcgggtccgc gcgcagccgc
     1261 tccaaagttt ccgggtcgtg cgcgacgtcg taacagaggc gatcgatcgc ctggacgctc
     1321 atccgcgagt cctttcttcc tcggccgtgg ctccgggacg catccatcgc gtcccggagc
     1381 cacgggtgtt gcacagtccg ggcaggtggt caggcgggtc cccaggccgc gaaggcgtgg
     1441 ccctcgccgt cccggtggtc catgagggcg aggggcaggt ccgcggccgt ctcggcggcc
     1501 gcgatccacg gcaggacctc accggcgacc gtgcccgcct cctcgatgcg ccgctccgtg
     1561 gcctcggcga ccaggccgtc caggtcgccc cggtgcagcc ggtcggcgac cgaacgggcc
     1621 caggccggcc gcggcacgcc gtacacctgg tcgggcagca cccggggtcc gcccacctcc
     1681 agcgagaagc tgccgctcgc gacgacggcg acgcggcggc ccggcaactc ctccagggcg
     1741 ttgcgcagca cccggccgag tcgtctgcac cgcgcggccg agggcctcgg ggccaccatg
     1801 ccgttcacat acacggggac gacgggcagc cggcgcccgt tgaggaagtg cagcggcacc
     1861 acgaccgagt ggtcgaccga gtggtccctg agggccaccg gatcgaagtc ctggccgacc
     1921 agaccccggt ggagcgccgc cccggcatcc gcggccagcg cgtaggacat gggggagacg
     1981 cccggcacgt cgtcgttggg gccgagggcg ctgtgcccgg tggcgacggc gaacgtcggc
     2041 cacatgtcgg gggtgaaggt gttgatgtgg tcgcaggtga ggacgacgag gacatcggcg
     2101 tccgcccgcg cgaccacctc gtccaccgcc gcgtagcgcc gcgccacctc cgcccccgac
     2161 tccgtgtcac cccgggccag ggcagggaac accggggtgt gcgggacccc ggcgacggcg
     2221 acgacctctg ccacgcgccg tcacccgccc agcgccggca cggcgttcgc ggccgcgggt
     2281 acggccgtgc gctcgccggg agcggtgggg ccgccggggc gggccgcacc gtacatctcg
     2341 cggagcagcc gcagtgtgtc caggcctgcc tcgccgtccg ccgtcatcct gcgcccgtca
     2401 cgtaccgcgg cggcgaagtc ggcgatctgg cggcggtggg agatgccgta gtagccgatg
     2461 ccggccgggg ccggctccac ctgcgcgccg acctcccgcg cggccgcgcg caacgcttcg
     2521 ccgccctcgg cgagatggag cgtcccgggg tggtcgaggt cgaagaggac cgagccctcg
     2581 gtgccgacca gttcgacccg ggtgcgccag gtgatgctgc tcgcgaccgt gacgtggtac
     2641 gtcaccagcg cgccctgcgg gccccgcagc agcgccgcca gcgtgtcctc ggtctccatc
     2701 ccgccacggg gtgccgtgtg tccggcggcc gcgccggtca cggtgaggcc gccgacgagc
     2761 cagcgggtca cgtcgagcgc gtgatagccc tggttgacca gggcggaccc gccctcgccc
     2821 gcgaaggtgc cgcgccagta actgtcggcg tagtaggcgt cgtcgcgccc gcactggagg
     2881 ctgacggtgc cggacacgag ctgtccgagc aggccgcccg cgatccagtc gcgcacggcg
     2941 gtgacgaccg ggtcgtaccg gtgctgcgag acgaccgaca ggacgcgccc ggtgcgctgt
     3001 gcgagggccg tcagcgcggt gccctcctcg acggtcaggg ccagcggctt ctccaccagg
     3061 acgtgcttgc ccgcttcgag tgccgcggcg gccagctcga agtgctgggc gtggtcgacg
     3121 gcgatggaga cgctgtcgac ctcggggtcg gccaggacgt ctcgcaggtc cgccgtcgca
     3181 cggggcagtc cgtaccggcg cgccagggac tcggcccgcg cgaggtcgcg gtcgcacgcc
     3241 cagcgcagtt cggcatcggg gagcaccgaa aagccgtcga catggttggg ggcgacgcgt
     3301 ccgcagccca ccacggcatg aacaaggggt ttcaccgaga actcctcgca tctcgcggtt
     3361 gcccggccgg cggcaacacg aaaaaggcgg tgccgggccg gttctccgct tcagtcaatg
     3421 tcacgtgact tccgaatgtc aatgtgcaga ggtatttccc tactcggtta gtgactccat
     3481 taatgactag ccttgacaag ctgtcatgaa gctacttgac tctgcgttgc ccggcgtggg
     3541 gacgccgccg cgaagaccgt cccccgggac caaccggagg tatccgcatg tatgcgccca
     3601 gcagcgcacc ctcgtccgcc ggtacgcaca ccgacgtcgt gccccacccc gacgacctgg
     3661 cccgccgcgc ccggcggcgc gtcgtcgaac tggccgcacg caaggcgatc cacctcggcg
     3721 ccgcactgtc catgaccgac ctgctcgccg tcctctacac ccgaggcctg cgctaccgcc
     3781 cggaccggcc cgactggccc gaccgcgacc tgctcgtgct gagcaagggc cacggcgcct
     3841 acggcctcta cgcgatcctg gccgaactcg gcgtcatcga ggcggacctg gcctccctgc
     3901 ccggtcatcc gtccgacgcc gtacccggca tcgaggccgc gaccggcgcc ctcggccacg
     3961 gtctgtccct ggcttgcggc atggccctcg gcgctcggct ggcgggccgg gaccagcggg
     4021 tcgtcgtggt caccggcgac ggcgaactcg acgagggcag caactgggag gccgcgcagt
     4081 tcgccgccca ccaccgcctc ggcaacctgg tcgccgtcgt ggaccgcaac cgtcttcagc
     4141 aggagggcga caccgagacc gtcaacgccc tggagcccct cgccgacaag tggcgggcct
     4201 tcggctggcg cgtcaccgag gccgacgggc acgacaccgg cgccgtcacc gaagccctgg
     4261 ccgcactgcg ggccggcgac ggtcccgggg tgctgatcgc ccacacggtc aagggcaagg
     4321 gcgtcccctt cgccgagggc gatcccgcct ggcacatggg cgagttggac gccgtacagc
     4381 gtgcgacggc actcgccgcc ctcgcccggg gcgagcggcc gtgaccggca tcgcacggct
     4441 cggtatgcgc gccgccctcg cccccgccct ggccgacgcc gtcgacgccg accccgcgct
     4501 gatcaccctg ggcgccgacg gacaggcgct gttccagggg gtcatggcac gtcacccgca
     4561 ccggtacgtc gacgtgggca tcgccgaggc caacctcgtc ggggtcgccg ccggactcgc
     4621 ccgcagcggc cttcgcccgg tcgcggccgc catggctccc ttcctcgtcc ggcgggccta
     4681 cgaacagctc cgcctcgacg tgtgcgtgcc cggcctgccc gtggtcctcc tcggcgtcgg
     4741 cgggggactg gggtacggac acctcggccc cacccaccac gccaccgacg acatcaccct
     4801 catgtcggcg ctgcccggca tgagcgtgca ctgcccggcc gacgccgccg acgccgtgtc
     4861 cgtgctgcgc accgtgctgt cggccgacgg acccgcgtac atacgactct ccgcgcgccc
     4921 cgacccggtg ctgccccccg cggcctccga cggcgacccg cgcaccgccc gtctcctgcg
     4981 cgacggcgac gacgtgctgc tcctggccac cggccggtgc ctggccgagg cgctgaccgc
     5041 cgccgacgcc ctcgccgccg acggagtgga ggccgccgtg gcctcggtga ccaccctgca
     5101 cgccttcccc cgggacgcgg tgcgggccct ggcccgcgac cgggcgctgg tcgtcaccgt
     5161 cgcggagtcc ctgggccccg ggggcctggg ggaccggacc gcgctgacgc tcggccggga
     5221 cggacctccc gtggtgcgac tggagaccga ccaccgctac ccaccggtgg cctcccacga
     5281 agaacttctc cacttctacg gcgtggacag ccgcggcatc cggtccgccg tgctcggcca
     5341 actcaccagg aacacgagga aagcgtgacg atgaggatcc tctccagcgc ccaggcgtgc
     5401 gggttcggcc ccgtctccaa actggtcgcc atcacccccc tgctcgccga cggcagcgtc
     5461 gacttcgtcg gccaggacgt cgcactcgac ttcgcccggc gccacagcca ccgcttccac
     5521 cgcatcaccg agggcgacac ccgccggtac gaggacgtcg cccagagcct cgccgacgcc
     5581 gacctcgtgg tcagcgtcat ggacgccgaa ctcgtcttct gggccgcccg cgccgatgtc
     5641 cccgtgctgt tcttcgacag cctcctcggc ttctggctga ccgggcgcgg cagcgaggaa
     5701 ctgtcggcgc gcgcccaact cgtccgctgg gccgatcccg agaccgcccg ctatgtcttc
     5761 gacacgctct ccccgcacga gcgcatcctg ctggcccacc tcctggcccg gcggtcgttc
     5821 gcgcagaact tccccggggt gcccgaacgc atcgcggccc tggccgaggc gggcatcgac
     5881 cacatcgaac tgtgcggccc catcgtcgac cgcagcgccc tggagaacgc cctcgtcctg
     5941 ccgccgcccg agcgcccggc cggactcctg atcaacctgg gcggcttcca gaacttcttc
     6001 ctcgactacg agtcccacaa cgcctacctc gacgtcctgc gccgctgggt ggccggactg
     6061 gccgccgccc gacccgagct gggccgcatc ctggtctgcg gcggagcgtt ccgcgagccc
     6121 gtcaccgaga cccacggcgc ggtcgaggtc gagtacgcct tcctgccgca gaccgagttc
     6181 ctgcggcacc tcgcccacac gccgctctac gcggtgcccc cgagcctcac ctcgctgcac
     6241 gagtccgtca tcctgcgccg gctgccgctg ctgctccccg aacagcacta cggccacatt
     6301 gccaacctcc gcgccctgcg cggcaccgtc gccggcgaca ccgcggccag cctcaccgac
     6361 ctcggcagca ggttcaccgt ccccgaggac gacctggaag gcaccaaggc gctggaccgg
     6421 ctcacacgcg aactgctcac ggacgagtcc ggctaccgcc acctggccca gcacctggac
     6481 gcacgcctgg ccgcctacca gaagctgacc gccgaggagc ggcacgcggc cgtcgacgaa
     6541 ctcggcgacc tgctcggcgg acacgcgctc gccgacctcc tgcaaggcgt cgacgcggac
     6601 ctcgtcaccg ccgggagggc gtcatgaccc acgcccccgc cacttgcacc tccacccgcg
     6661 gcactcccgc ccccgccgac ctggccgacc tgaccgaacg gaccgtggac accgacgagg
     6721 tggcccggct gatgctcgcc gcccacctgg ccaggaccgg cacgcccgag cccgcccccg
     6781 accgggtgcg gtccaccacc tggacaccgg ccggcgcccg taagatccgc cgccgcacct
     6841 tcgtgcaact cgacatcgac ggtgtgcccg tcgccgtcgc caaggtcccg ctgtccacca
     6901 ccgacccgaa actcgcccgc gaactggaga tcctccgcgg cttcccggca cccgccccgc
     6961 tgggcagccc ggtgcccctc gacgcgctgt gcggcggctt caccatgagc catctgcccg
     7021 gtgtcgacct gcccaccgcc gtcaccggcg ccgacggacc cgacgtgctg tggcaggtgc
     7081 tgcgccccgc cgtcgaacgc gtcgccgagc tccacctgtc cgcggaccgg gtgccctccg
     7141 gtcccgagcg tgccctggag acggccgccg cgtacgtccg caaccccgag ttcggcgtcg
     7201 agcacgccga ccaggcgctg cgcaccgccc tgctcgcgcc cacccacggc gacctcggcc
     7261 cgtggaacgt gcgctacgac gcccgtgacg ggtcggcccg tgtcctcgac ttcgaggact
     7321 accgcgccac cggcatcgcc gccatggacg tggtcaacct cctcgtcacc accgccctcc
     7381 cggtcttccc cgactacccg gaacacggct tcgactggct gtacgaccag gtcttccgca
     7441 cggaccactg gttccggtcc gtgctggaac ggggcctggc ccactacggg tcgctcaccg
     7501 gacagcaccc gggccgggta ctggatctgc tgcccttcac ctgccagtgg ctcatcgaac
     7561 gcatcgaggc cgagggccgc gacaccagcg ggctgttcta ccggaccttc gtcgagcgcc
     7621 atctggagcg ccggcccgca gccttcggga gcgaccatgc ctgagcagac ccgcacgacc
     7681 agcacggacg ccgtcgtcat cggcggcggc cccgccggac tgttcgccgc actcaccctg
     7741 gtccgggcgg gccggcgagt cgccctcctg gaagccggcg gcgacatgcg cgagagcctg
     7801 tgctcccgcc tggtggcccg catggacggg cgcacggtcc gtgacgcgga gaagttccgg
     7861 ctgcagtgcc cgcgctgcac ctgcctcacc ggactcggcg gtgccgcctt ccacttcgac
     7921 accaacctcg gatacatctc ctccctcacc cgctccaaga tcgagtccgc gcccgacggg
     7981 acggtccgct cgtacagcgg actggagcgc gcgctcggct ccttcgaccg cgcgcaggac
     8041 ctcatcggcg aggcgtaccg catcttctac gagctggggc tgccgcccgc cgggccgccg
     8101 cgggaggaca acggcccgct gctcggcgag ggcaccgtct tccagcacgt cgacacggcc
     8161 tactcgcaga gcgtcaccgt ggacgactcc ctcgtcgtcg tcgcacgcct caaggacgag
     8221 ctggacagcg gcggcgggag cgtcctgctg caccaccggg ccaccgacgt cgaaccgctg
     8281 accggcggcg gattcgaggt ccgcgccgac accccgcacg ggcctgccgt cttccgggcc
     8341 gacgacgtca tcgtgggggt cggcaagctc ggcctgccct gggtgcgcga cctcgcccgg
     8401 cgcatcggag tccgccaccg gcccagcagc cgtgtcgacc tcggcgtccg gctggaggcc
     8461 gaccgcgcgg acctcgcgcc gctgctggac ggctgccaca accccaagct gtcgttcctc
     8521 aacgaggagg gccactcggt ccggacgttc tgtgtctgcg agggcggccg cgtcatgcag
     8581 tacggcttcc tggacgccgt cgcgctcgac ggacagcact gtctgaacca gcccacgacc
     8641 aagtccaacc tcggcatcct caccacggtc gacctgcccg agcacatcga cggcaccgag
     8701 cacgccgggg agttcgcggc gcgcgtggcc gcacacggcg gcggacggcc cgtcgtcagc
     8761 accgtcgacg aactggccgg acggcccgcg cccgagggac cgctcaccac cagcctcatc
     8821 aactaccacc acggcgacct gcgcgactgc ctgcccgcgt ccatcgtccg tgacgtcctc
     8881 gccatggtcg gccgcctcaa cacccttcat ccgggtctcg tcccgggcac cgccaccgtc
     8941 gcggcacccg tcgtcgaacg cctcttcccc gacctcgacc tctccgacga cctggagtcg
     9001 tccgtgcccg gcctgtactt cgtcggcgac agctcctcca agatcatcgg catcacgtac
     9061 ggcgcggcca ccggcatggc cgcggcccgc tccgtgctgc accgccgggt cacaacggcc
     9121 gccgcggcgg gcgggaggca ctgatgctcg tcctgcccca gcgcctgccc accgccacac
     9181 cgccccgccc cgagcggacg tcggcccggc tcaccgcccc cgcggcccgg ctgctcggcg
     9241 cgcccgaagg gcaccgggtg ctcgcggccc tcagccgtct gctgctccac cggtacggag
     9301 cgggctggga ggtcttcggg acctccggcg acaccctggt gcgccacgcc tgcgccgacg
     9361 accaggagac ccccaccctg gcggaactca cgggcgccac acgtccggtc gcggcggacc
     9421 tgccggtcga cggtgaaccg tacgtggccg tactggccga cagcccggcc gtaccgcccg
     9481 cggtgctcgg gcgccccgtg tggaccgccg ccgccgacgg accggccctg cgcctcaccc
     9541 acgacgccgc cgtcgtcgat gccgccacgg ccggccgtgt cgccgagcac ctggccctgc
     9601 tcgcccacca caccgccgta cggccccgga ccaccgcggg agaagtcgac ctccttctcc
     9661 cggacgagcg gaccctgctg ctcgacacct ggaacgcccc gcacaccgtg cacgcggaca
     9721 ccacgctgca ccgcatgttc cgcgagcagg ccgcccgcac ccccgacgcg atcgccctgc
     9781 gcgacggcgg cacggaggtc acgtacggcg aactcgacgc ggactcagac cgcttcgccc
     9841 ggcggctgcg cccgtacgtc accgaacccg gcgcgctcgt cgtgctgagc ggtgaccgcg
     9901 acactgccct gttcaccgcc gtcctcggca tctggaaggc cggcggaggg ttcgtccacc
     9961 tcgacccgca cctgccggac ctgcgcgtcg aggagatcct tggcctcgtc gatcccgtcg
    10021 ccgtcctcac caccggaagt gggcaccgcg ccgtcgccgg ccggagcctg cccgtcgccg
    10081 acctcctcga cccggccgcg ccgcccgccg ccccgcccgg cgcacccgag gacagggcac
    10141 gccccgacaa cacggcctac gtcctgttca cctccggcag caccggcacc cccaagggcg
    10201 tcgtccgccc gcaccgcatg cacacctcgc gcatccgtct ggagcagggg atgtacggca
    10261 tgggccgcga cgaccggcat ctgctcaagt cacccatcag cttccgggag ttcgcatggc
    10321 cgctggcgac cggcggcacc gccgtcctgg ccgcgcccgg caaggaccgg gacgaccgct
    10381 acctggcgga gctgatccgc gacgagcgga tcaccaccgt cagcttcgtg ccctccatgc
    10441 tgcggctgct gctcacccag cccgcgttcc ggacggcgcc cgcactgcgc cacgtcttcg
    10501 tcggcggtga ggcactcggc caggacctgg aggacgaact gcgcggcctc ggcctcgcgg
    10561 tccacaacac gtacacgctc agcgaggccg actacgtctg ccatcgcacc ggaccgctcc
    10621 ccgagccccg gcccgcacgg accggcacgg tcgtcggcgt cccgctcgac atgcggatct
    10681 acctctgcga cgcggcgggc cggctcgtgc cgcccggtgt ggtcggggag atcaacaccg
    10741 cgggccccgg cctggccgac ggctatctca accgcccgga cctgaccgcc gaacggttcc
    10801 ggcccaacca cctggacccc gccggtcctc cggtcctctt ccgcaccgga gacctggccc
    10861 gccatctgcc cgacggccag gtcgagtacg tcggacgcgc cgacgaccag gtcaaggtgc
    10921 gcggccagcg ggtggaaccc accgaggtcg aaacggtgct ccgcgggcac cccggggtcg
    10981 cgaacgcggc ggtcgtcggg ataccggacc ccgatcaggg cgccgtcctc gtcgcctacg
    11041 tcgtgcccga cggcgaggag gtgccgcccc agcggctgcg cgagcatctc gccgcccggc
    11101 tgccggactt catggtcccc gcccatgtgg cctcgacccc cgccctgccc ctgctcccca
    11161 gcggcaaggt cgaccgcaag gcgctgcgcg tcaccccgcg cacccgcccc gcgctcgacg
    11221 tgccgtacac cccgcccgcc acacccggcc aggaacgggc cgccgcgctg gtggcgcgtg
    11281 tcctcggact cgacaccgtc ggcgtcgacg acgacttctt cgcgctcggc ggcgactccc
    11341 tccgcctgat gctgctgcgc ggctcgctgg agtcggcctg cggacgggag ttcgccctcg
    11401 cggacgtctt cgccgcccgt acgccgcgtg gttacgcccg tctgctggag gacaccgacg
    11461 gcaccgccga cgccgattct ctccgccgtc cctccgaacg gcgccgtccg ccgccgcgcc
    11521 gcacggccgc gtcggccacc cgcacccgca cccgctcgtc cgaaggaggt gaaccgaggt
    11581 gaacgccccg ttgcccgggc cgccggcccc gtccgcggac cacgacgaat gggccgtggc
    11641 cgtcgtcggc atggccgtac gcctgcccgg ctgcgacagc ctcgaccgct actgggagat
    11701 cctcgactcg ggcgaggaca gcgtcacccg acgcgagcgc acctccggct cgttcgtccc
    11761 ggcctacggc tccgtgcccc gtcccgccca cttcgacccg gcccgcttcg gcatcgcgca
    11821 ctccgaggcc ctgctcctcg acccgcagca ccgactgctc ctggaggccg ccgacgaggc
    11881 gctggaggcc gcgaacgtcg accgtgtccg cacccccggc atcagcgtct acgcgggggt
    11941 cggccacaac gagtacgagc gctgggtcgg caccgccctc gccgggcgcc ccggcgtcga
    12001 cgcccaggcg ctggaggtca ccaaccgggg cgactacgcc gccacgcgcg tcgcgtaccg
    12061 cctcggcctg cagggcgccg ccgtgaccgt ccagtccgcc tgctccaccg cgctcaccgc
    12121 cgtccacctg gcggcccagg acctgctgag ccacggaagt tccctcgccg tcgccggtgt
    12181 cgcctccgtg cgggttccgg cgccgggcgg atacgaggcg ccgctcggcg gcatcggttc
    12241 gccggacggc gtatgccgcc cgttcgaccg ggcggcgggc ggttccgtgc ccggcgacgg
    12301 cgccggtgcc gtggtcctca aacgactggc cgacgcgctc cgggacggcg acgacatctg
    12361 ggcggtcgtc cgcggcaccg ccatgaacaa cgacggctcc ggcaagtccg gcttcgccgg
    12421 cgtcgacccg gccgcgcagg ccgaagtcat ccgggccgcg ctggacgtcg ccggactcga
    12481 acccgacgac atcgactacg tcgaggcgca cggcagcggc acccgcatcg gcgacgcctc
    12541 ggaatggacc gcgctccacg aggtcttcgg cggcgtacgc caccgggtcc atgtcggcgc
    12601 cgtcaaggcc ggcctcggtc atctgcgcga agccgcgggc ctcgccggac tggtcaaggc
    12661 cgtgctctcg ctgcgccacg gccggctcgt cgccaccccg cacttcgagc gcctcccctc
    12721 cgatctcgcc cgcagggaag ggccgttggc cccgctgggc gaagccctcg actggccggc
    12781 cgccggacac cgcccacggc gcgccggggt gagcgccttc ggcctcggcg ggaccaactg
    12841 ccacatcgtc ctcgaagagg ccccgccccg cgcccgcgac gccgcggcgg ccacgggcga
    12901 ggcggaactg gtgctgctct ccagccacca ccccgacgcg ctgaccgccg acctcgatgc
    12961 cgtacgcgac cacctggagc ggaacccggc gcggacgggc gacaccgcct ggaccaccca
    13021 gaccgcacgc catcgccacc cgcaccgcgc ctatgccgtc gtcacccccg cagcaggcac
    13081 cgaggcggcc ttcgcggccg accggctgcg tgtgcagcag ggacgggccc cggccgatgc
    13141 gcccgaggtc gtcttcgtcc tgccgggcat cggcagccac tacctcggca tgggcgccga
    13201 cctggcccgc accgatcccc tgttcgcggg ccatctgcgg gccgcagtca cggtcgccga
    13261 ccaactcacc gacggggccg tcggccggtc cttcgcctcc gggcaggagc gttcctccgg
    13321 cgacggcaac cgggtcgatc tgcgcgccat gctgcgccgg gacggtgcca cgccgtcgcc
    13381 ccgccggcag ctgcgcgacg tccatctgtc cctgttctgc ctcgaacacg ccatggcccg
    13441 caccctcatg gacctcggca tcaggcccgc cgccctcctc gggcacagcc tgggggagtg
    13501 ggtggccgcc gtcctggccg gcgtcatcgg cctcgacgac gccatggcgg ccgtcgcgcg
    13561 ccgcgccgac ctcgtcgtca cggccgggga gggcgccatg ctcggcgtgc tcgccgccgc
    13621 cgacgacgtc gagaagtacg ccctcgacga cacctggctc gccgccgaca acggaccggg
    13681 gcactgtgtc ttctccggcc gccccgccgc catctccgcg ctcgccgacc ggctgcgcgg
    13741 cgacggcttc acggtcctgc ccgtcgacac cgcgcacccc ttccacacgc cccagctcac
    13801 ccgggccgcc gacctgctcg gcgaggacct gcgcgaggta cggctgcacc cggcccgtat
    13861 tccgatcgcc tccagtgtcc tgggctcctg gctcgacggc gggatacccc aaccctcgta
    13921 ctggcgcgac cacatggtcg gccgtgtccg cttccgtacc gccgcgggac tggtcctgga
    13981 ccggcaccgc gtcctgatcg aggtcggccc cggcaccacc cgcccgtgga tcggccagac
    14041 cgccccggac gccgtgtgcg tgcgcaccgt ccggcagtcc tacgagcacg tgccggaccg
    14101 gcagatcctc ctggaagccc tcggcgagct gtggacccac ggggtcgagg ccgactggca
    14161 gcgcctgcac ccggcccccg gacgcaggac gaccctgccg cccaggaacc tggtgcgccg
    14221 caggtttctg ccggactcgg cgccgcccgc cgacccctgg ccgggcaccg cgtccgcacc
    14281 gccggccgac gcgcccctgc ccgccggtcg ggacgacacc gcggagcacg agcggacgcc
    14341 cgtggcagga ggggcggcgc cctcgaccgt gtccggaccg gctgcgccct cgaccgtgtc
    14401 cgggttcctc gcggagcggt tccgcgtcct gctgggcctg cgcgaggtcc accccgacga
    14461 ccacttcttc cacctcggcg gcgactcact gatgggcgtc catctgatct cggggctcaa
    14521 gcagctcacc ggacggtccg tgccctcctc ggtggtcttc gcctcggcga ccctcggcgg
    14581 catgacacgc gaggtggaga actggctcgc caccccggcg ccgcagcaac cggaacccag
    14641 cgagaacggg agtcgtacgc catgaccgca cccacgatcg gagtgctcgg agccggagtc
    14701 atcgggtcca gcgtcgccca cgccgccgcg gcggccgggt acacggtgac actcgtcgac
    14761 tccgacgccg ctgccctcga caccgcccgc accaccatcc gccgccacca gcggctcgcc
    14821 accctcctcg gcggcggccg gagcgcccac gcactggaca tccgcccctc caccgacctc
    14881 gccgcactcg cggacgcgga gctcgtggtg gagaacacca ccgagtccga ggaggccaag
    14941 cgggccctct acccggcgct ggaagacgtc atcgcaccgg acaccaccat cgccgcgaac
    15001 acctccgccg tccccatcgg ccggctcgcc gagcggctcg ccgaccccgg ccgggtcgtc
    15061 ggcgtccact tcatgaaccc ggtcgaccgc atcgacatgg tggaggtcgt ccgcggcaag
    15121 gccagctccg acgcggccat ggcggccgtg gacacgctgc tgcggcgcat gggcaagaag
    15181 gccgtcgtcg tcgaggacgc gcccggattc gtcatcaacc gcgtcctcat gccggtcgtc
    15241 aacctcgccg ccgccgtcgt cgcggacggc gtcgccaccc cgagccaggt cgacgagctc
    15301 ttcaagggct gcctcggcca cacctcgggc cccctgcgca ccgcagacct catcggcctc
    15361 gacaccgtcg tccgcaccct ggaggtgctg cacgaccact acggcaccgg tgagttcgtc
    15421 acccacccgg ccctgcgccg gatggtcgac cagggcctgc tcggcaccaa gagcggccgc
    15481 ggcttctact cctacgacgg gaactgaacc atggcttccc agccgaccac cgctacgccc
    15541 gccccctcca cagcccccgc agcccacgaa gtgaccgacg ccgtacggca gttcatcgcc
    15601 cggctgagcg ggcaccccga catcgcggac gaccggccgc tcatctccga cggtgtcctc
    15661 gactccgtgg ccgccgtcca gatggtcgac ttcgtcgagc gcaccttcgc catcgagatc
    15721 gccgacgagg acctcgaact cgccaacttc gactcggtcc aggggcttgc cgcgctcgtc
    15781 caccgcaggc tggcggcgtc gtgaccgaat ccgcgcccga ggcactcctg caggcgctgc
    15841 gcgacgacgc gttcgccgcc cgggccacgg cctgggaacg cgccggagcc gtaccgcgtg
    15901 aggacatcga cgcactggcc gcgctcgggc tgctcggcct caccgtggac accgcccaca
    15961 agggcagcgg cacaccggcc gccgccgtca ccgaggtgca tcgcctggtg gccgccgcct
    16021 cacccagcct gcacagcctg ctggtcgtgc acgccatggt ctgccacgcg gtacagcgct
    16081 gggccgggcc cgaactgcgc gacacgctgc tgcccgagct ggcgaccggc cgcacgctcg
    16141 ccgcgttcgc gctcaccgag gaggaggcgg gggccgactt cggcaacctg accaccacca
    16201 tcgaagagga cggcggctcg ctgcgcgtca ccggcaccaa acgctggctc tcgttcggcc
    16261 ggatcgccga cacctacctc gtcttcggca ccaccgcggg gcgcggcagt tgtgcgctgg
    16321 tggacgcggg accgggcgtg cggatcagcg cggaacccgt cacggcgggc ctgcgcgccg
    16381 cccggctcgc ccgcgtcacc ttcgacggcg ccacggcacc cgccacgcgc gcgatcgccc
    16441 gccccggctt cggcgttccc ttcgtggcca cgtcctgtct gaccctgggc aggctgtacg
    16501 tcgccgccgg cgcggtgggc gtcgcggagg ccgcgctcgc cctggccacc cggcacgccg
    16561 ccacccgcac ccacggcggc accaccctgg gtgaacggca gctcgtacgg ggcctgctcg
    16621 ccgacgccgc gctcgccacc gacgccgccg cccgctacgt acggcagacc gcgcacgagg
    16681 tcgcggaccg ggagccgtcc gccgtggtca cggcggcccg cgccaaactg ctggccacgc
    16741 gcgcggcgag cctcacgacc gccaccgcct cccggctcct gggcgccgcc ggacagaccg
    16801 aggaccaccc gctggcccgc ctgcacgccg ccgcccgcgt ccacgaggtg atcgaggggc
    16861 cgaccgaagt actccaggac atcgtggccg ccgacctcct gcgcggccgg gccgccgcgg
    16921 acggcgcccg gcctgccacg gacggcgccc ggcccggaaa ggaccacgcc catgccgacc
    16981 gctgatccgc gcaccgcccc ggccccgcag gtcaaatgcg tcgtctggga cctcgacgag
    17041 accctgtggg acggcaccct gctggagggc gacgacctca gcgtgcccga ggccaaccgg
    17101 aagctgatcc ggaccctcga cgagcacggc atcctccagt ccgtcgccag ccgcaacgac
    17161 cccgacgccg tcaccgaaca gctgcgcgcc ttcgggctcg ccgagtactt cctgtaccca
    17221 caggtcggct ggtcggccaa gtccgcctcg ctgcgcgccg tgacccggga gctgaacatc
    17281 gcccccgaca gcgtgctgtt cgtggacgac tccgagttcg agcgggccga agtggccagt
    17341 gaactgcccg aggtgcggtg catgacccgg caggagctgc acgcccgggt cgccgacggc
    17401 gccgtgctgc cggcacacgt caccgacgac gcgcgccacc gccgggagtt gtacctggcg
    17461 gaaagcagac gccgcagcca cgagggcgcg ttcgacgggc cggcggagga gttcctgcac
    17521 tccctcggta tgacgttgca cgtccgcgag gcgaccgcgg gcgacctcgc ccgcgccgcg
    17581 gaactgaccc agcgcaccca ccagctcaac accaccggca tcaccttcga ccaggacgaa
    17641 ctggcgtccc tgatgagcga tcccggtcac cgcgtgctcg tcgccgaact cgacgaccgc
    17701 ttcggcacct acggcaccat cggtctggcc gtgctggcca ccggccaccc ggacacctcc
    17761 gcggaccgcg aggccggcgc cacgcgccgg tggacgatcc gtctgctgct gatgtcgtgc
    17821 cgggtcatgg gccgcaacgt cggcaccacc ctcatcgccg ccgtgtcccg gctcgccacc
    17881 gcccacggcg ccgcgaccgt cgcccacttc cgccccaccg accgcaaccg gcagatgctg
    17941 ctcacctacc ggttcgcggg attcaccgtc gagtcccgca ccgaggacct ggtcgtcctc
    18001 accctccccg acgagctgcg cccggccgtg ccgggatatg tgcgcctcgt cctcgacgac
    18061 accgccgccg cctccccgcg cggcacgaca caggagctga ccgcatgaag gccttcaccc
    18121 agagctggac cgacaccttc tcctccgtct actccgagga gccgctcgcc aaactgtcct
    18181 ggttcaacgc ctcgccgggc ctggaactca tcaagcgcgt catcgacggc acgctcaagc
    18241 ccggccagcg gctcatcgac ctcggcagcg gcccgggcgt cgacgccgtg ttcctgtccg
    18301 tgcagggcct cgacgtcacc ggtgtcgacc tgtcggcgga cgcggtcgtc cgcgcccgca
    18361 ggtgggccga actcgcggga gcctccgccg acttcatcca gggcgacgta ctcgacgtac
    18421 cgctgccgga ccactccgcc gacgtcgtga cggactcgtt cgtcttccac aacatgcgcg
    18481 acgaggcccg cgaaccctac gccgacgagg tgcaccgcct gctgaagccc ggcggtctgt
    18541 tcctgctcaa ctcgttctcg gaccacatgg tcgagggcac cggaccgcgc cgcatcacca
    18601 gcgaggagat cctcggcacc ttccgctccg accgcttcga gtgcgtcggc ctgtacgtct
    18661 accgcaacgt ccccacccgc accaagcccg atcagctgca ctggttcggc gagttccggg
    18721 cccgctgatg cgggtcgtcg tcacaggcgg cggccggggc atcggacgtg ccgtcgcgct
    18781 cggtttcgcc gagcgcggcg cgcgggtcgc cctgctggcc cgcaccgcct cccaggtgcg
    18841 gtcggtggcg gacgagatcg aggcgctcgg ggccgagagc ctcgcgctga cggccgacgt
    18901 cgcggacgag aaacaggtgc tgcgatgcgc cgagcaggtc accgagacgt tcggcggcct
    18961 ggacgtgctc gtcaacgccg ccggggtgtt cgacctgggc cccaccacgg agttcccggc
    19021 cgaggacgcc cgcgggctgc tggccacgaa cgtcatgggc accttcctca cctgcaaggt
    19081 cttcggcaga cagctgctgg accaaggcca cgggaaggtc gtcaacttct gctcgctgct
    19141 gtcgtacacc gcctttcccg aacgggcgct gtacgcggcg agcaagggcg gggtcctcca
    19201 gctcacccgc agtctgggcg tcgagtgggc cgcacggggc gtcaatgtca acgcggtggc
    19261 tcccggcatg atccgtatcg agacaccgca cccggccgcg ctcgccgagg acgcgatcgt
    19321 cgggcgcata cccgcccgca ggcgcggcag tccgcgggac atcgtcggcc ctgtcctttt
    19381 cctggcctcc ccggaggccg actacatcaa cggccagacc ctggtcgtcg acggaggctg
    19441 gctgagctat ggatacctct gaacatccct tgtccatcgg cgtcttctgc ggcgcctccg
    19501 ccgggcgctc gccgcggtac gccgaggtcg cggccgagct cggcacccgc atcgcggcac
    19561 gcggccaccg gctcgtgtac ggggccggcg gcgtcggcat gatgggcgag gtcgcccggg
    19621 ccgccgccgc gggcggcgcg ccgatcctgg gcgtcatccc cgagttcctg cgcacccgtg
    19681 agatggggga cgaactgccg ccgcaggaac tcgtcctgac gacggatctg ctgcaacgca
    19741 aacgcatcat gatcgacagc gcggatgcct tcgtcgcgct gcccggcggc tacggcaccc
    19801 tcgacgagat cctcgaagtg gtgtccatgg ccgctctcgg acagcgcgtc ggtccgctcg
    19861 tcctcgtcga cgtggagggc gactgggacc cgctgcggcg gctcgtcgag ggactcctgc
    19921 ggcggggctt cgtccgcgac gccggactcg tccgcgtcgc cgccgatccg gaccaggccc
    19981 tcgacctggt cgccgccgcc cgcaccggtg ccctggcggg agcgttcgat gccggcgtgt
    20041 gaacaccgca cggaggtgga ccggtgaaaa ccgcggcacg acgtgagccg ctgccccgat
    20101 acgcggggtt cctcaccggc tggggcgcca ccacgttcgg caccggcctc gtgctgccac
    20161 tcaccgtggt ctacctccgg gagacgctcg gcctgcccac ctccggcgtc tcgctgtact
    20221 tcgcgctgtt cgcgctggcc ggactcgccg tgaacccgct cgcgggcagg gccggcaagg
    20281 tgtacggccc cggcctcgcc gcgatcggcg ccacggtcct gcaggccgcc ggcgcggcct
    20341 ggctgacggc ggcgggctcc atggccgcca cggtgcccgc cgcctgtctc tccggggcgg
    20401 gcaccggcgc ctactacgcg gtccagacac cgctgctcac caaggccttc ggcaacgccc
    20461 gcctcagccg ggtcctttcg gggcagcacc gtgtctccgc cctgaccatg gcggtcggcg
    20521 cgctgctggg cggccaggcg gtggaacgcc tgggggagcg gggctacacc tggtgcctgg
    20581 ccgtcaacgc ggtcagctac ctggtccacg gggccatgct ggcccgactg ccgcgggcgc
    20641 ggctccggcc cgccgggtcc ggtgtggacg gcgcgggacc ggacctgccc catggtgtgc
    20701 gggacggccg cagcgctgcc ctgcacgaca cggtgttcct gcggctgctc ctcgtccaga
    20761 ccgcgctggt cgtcttcggt atcgcccagg tcgacgccgt ggtccccgcc atcctgcgca
    20821 acgccgatct gtcggtgtcg gccgtcagcg tcgtcatcgc ctgcaacacc gtcggcgtga
    20881 tcgtcttcca gggcctcgcc ctgcgtgtcg tcgaacggat cgggtacgtc gccgcgttga
    20941 cggcggccat cgtggtgtgg gtcgccgcaa tggccgcgct gacggccgcc gtgctgatgc
    21001 ccggtctccg gctgcgcctg ctgctgggct ccttgttcgg gctgctgttc gccatcggtg
    21061 agtgcctgat cgcgccgagc gtccagcccc ttgtcacgct gaccgctccg gcggggcggc
    21121 tggaggggta cgccgcggcc acctccctcg cccatggcct cggcgcgttc gtctcgcccc
    21181 tggtgctgct gcccgtggtg gacggcggcg gggtgtggag ctatctcgcc ctccaactcg
    21241 gcggctacgg cctcgcgttg tacgccctgc tctcgttccg ggcccgtagc gtccgccgcc
    21301 tcgcgtcctc acccctcagc gaggagacca cgccctgaag ccgccgacga cgacgcatcc
    21361 accgacgacg acgcatacgc cgacgacggc tcatacggcg cggcccgcac ccgacgatct
    21421 gccgggaccc ggcgaggcag ccctctggac ggtccggctg gagtccgtcc ccgtcgcacg
    21481 ggccgaacac gtcctcgacc gacatgagtc ggcgcgagcg gccgcgttcg gcgacggccc
    21541 cgggcggcac cgctacgtcg cctcgcacct cgcgctgcgc accgtcctcg gcggctgcct
    21601 gggcatggag cccggcgagg tccggctgac ccgcgagatc tgcggtctcc cgcactgcgc
    21661 acgcccccac gggcggcccg tgctgagcgg cgcgagtcca cccgtccagt tctccctgtc
    21721 ccgctcgggc gacctggcag tcgtggcgct cgcgacggtc cccgtcggcg tcgacgtcga
    21781 gtcgcgcgcc ttccgccacc cggacagccc cctcgacggc atgatccgcc ggctccaccc
    21841 ggccgagcgc gccgcgctcg cccgactgcc gcccgcacaa cgggaggagg gcttcctgag
    21901 ctgctgggtg cggaaggagg cgtacctcaa gggcacaggc acgggactgc ccggcggact
    21961 ggcccgccac tgcgtgggcc tggccgccga actcgctcct ggcggcaggg gaccggcgcc
    22021 gaccccgcgg ggatggacct tcctcgacct cgacctgccc cccggccacc gcgcggccct
    22081 ggccgtcgcc caggtaatcc ggggtaattt tccaacccta tttcatttaa ctccacgaga
    22141 gattagtgac tcgcttaatg actaatcttg acaagcagtc acaagaatac ttgactctgt
    22201 atcgctcgac cgaaccgaga ggaagacaca tgacgcacga cagtgcgggc cgccgggaaa
    22261 cgctgctcgt cgtggggtcg ggctatcgcg ccggccacga gcgcctgctg gcccagatgg
    22321 cggcggacgc cgacctgatc ctgctcaacc ccgaaccggt gagctggcag cgcgactggg
    22381 tacaggccgc cgaggtcttc gaccccgccg acggcgatga cggcgtgctg cgcacggcca
    22441 agaccctcgt ggaccgacgg ccggtcgcgg ccgtggtcac ctacgaggag accatggtgg
    22501 tgaccacggc ccggctggcc cagagcctcg ggctgcccgg tgtgccggtg gcggccgccg
    22561 aactggcccg ggacaagcac cgccagcgca cgctgctcaa cagcaccggc atctcaccca
    22621 cccgctccgt cctcgtccac gacctgcccg cggcacggcg ggccgcacag gagatcggct
    22681 acccgctgat ggtcaagccg cgcggcctgt ccggcagcgc cggggtgcgc cgggtggacg
    22741 aggagtccca gttcgacgcc gccttcgacg ccgccgtgaa cgcggacaag aggggcctgg
    22801 agagcgaagg ggtcctcgtc gaggagttcc tggagggctt cgagttcgac gtggactgcc
    22861 tcgtgcacga cggaacggcc accccggtct cctgggcacg caagatctgg gcgtacgacc
    22921 cctatccgat cgaggcgggc ttcatcaccg gccacggcac gctgggccgg gccgagatga
    22981 cggagggctt cgacctcgcc tgccgcagcg tcctggccgc cggcatcgac cgcacggtgg
    23041 cccacgtcga agtgaagatg acgcccgccg gaccacgcat catcgagctc aacgcacgcc
    23101 ccggcggtga catcgcctcc cggatcgtcg aactcgcccg cggcgtacgg ctcggttcgc
    23161 tgctcgtctc ggccgcgctg gggcgcgcgc cgcacaccgc ctccagcgac gaccgctcgg
    23221 ccggcatccg cttcctgtac ccccgctccc gccggcgctt cgacggcctg gccgaggccg
    23281 cccgactgcg ctcccgcccc tgggtccacg agatcaggga actgcacccg cgcggcgaga
    23341 cggtggcacc tccgcccgag gacctctacg gccgggtcgg ctacgtgatg gccaccggcc
    23401 cgcacgccga cgaggtcgag gaccgtctgc tcctcgccca ccacgaactg cgggtcctcg
    23461 gctcctgacc accccggcgc cccgccccgc accgaccacc cgaaccccct caccaccgac
    23521 cacgagagag gcacacgcca tgaccgagtg gaagcccgag acgtacggcc cccgctggaa
    23581 gaacgtgtac gaccacatcg actggccgca gcccgagggg gccgtcgagt tcctggccaa
    23641 gcgcgcgggc agcggccggg ccctcgaact ggccatcggc accggccgcg tcgccatccc
    23701 gctcgcccgg ctcggcgtgc ccctcgacgg gctcgacgcc tccccggaga tcgtcgaggt
    23761 gatgcgcggc aagcccggcg gcgagtccat cgaggtgtcg atcggcaaca tcgccgactt
    23821 cacctcggag cgccgctact ccctcatctt cctgctgctc aactcgctgt acgcgctgca
    23881 gacccaggaa gagcagatcc agtgcttcga gtcggtggcc gcccacctgg agcccggcgg
    23941 gctgttcgtg gtcgagacgt tcgtacccga ccccacccgc ttccacttca acgggcgcgc
    24001 ccatgtgtac gacgtcgggc tcgaccacgt acgcatcgag gccgacacct tcgaccgggc
    24061 cacccagcac atcaaggaga accacatcga gatccgcgag gacggcatca ggctctaccc
    24121 cgccttcctg cgctacacgt ggccctccga gctcgacctc atggcccgca tcgccggcct
    24181 cgaactcagc gaacgctggg gggactgggg caacgtgccc tacgacacct actcggagaa
    24241 ccacatcggc gtctaccgca aggcgagctg acacgatgcc ggacggactg gcacccaccg
    24301 tcctgacccc ggcggtggcc gacgcccgct gcgatcccgg tctgccgccg gccggaccgc
    24361 gcaccgggcg gccccatccg gtggcggcgc tggtggaccg gatcggtgac ctgttcgtac
    24421 cgctcggctt cgacctggtc caactgccgc tgctggagtc ggtccgggac aacttcgacg
    24481 tcctcggcta tccgcccgac caccccaccc ggacccggct gagcctcttg cccgcacccg
    24541 acgtggtgct gcgtacgcac gcgacctccg gcggcccgcg ggccatgcgc gccgctgccc
    24601 ccggaccgct gcgggcgctg ctcgtcggca cctgcttccg caacgaactc tcctccccct
    24661 actccggctc gcagttcacc cagatcgacg gcctggtggt ccagccggac gtgggcctgc
    24721 cggagctgat ggggctcttc gaccgcctgg tgtccggtct gttcggaccg ggccacccct
    24781 ggagggtccg gcgcggcggc taccccttcg ccgcgccggg gttcgcggtg gaggtggcct
    24841 gcccgcgctg cggtcccggc tgcgacgagt gcgagggacg cgggcacgtg gagatcggcg
    24901 ccggcggcct cctgcgtgcg caggtgctca ccgccggggg ctacgacccg caccgggtga
    24961 ccggtctgag cttcggctgc tcggtcgagc gcctgctcag gctcagccac gggctgaccg
    25021 acatccggga actgctggtc aacgacatgc gcctgctgga gcagttcgag cacgcctacc
    25081 tgccggtcgg gccgtccgag aagggagttg accgaccgtg agaatccccc tggcctggct
    25141 ggagcgggaa tgcggcggcc ccgtcgaccc ggaggagctg ctggacggcc tccgtgcgag
    25201 cggggcacgt gccgcccttg ccgacgcccg cgcggtggac gtggagccgc cgcccgaact
    25261 cgcgcatctg gcttccgtgc gcggtctggc ggccgagata cgcgcgcgcc acggaggcac
    25321 accctccccg cccgcgcgct cgccgcggct ggcggacggg ctcgcgatga cggcggacga
    25381 gcaggtgccg ggccgggtgg cggcagccgt cgtccgcctg ccgggcccgg tccgcctgcc
    25441 cgccgacgcg gccgaccggc tgcgcgcggc gggggtgcgg ctcaccggga cggtcgccga
    25501 cctcatcgcg tatgtcgcgc tggaaaccgg tcagcccctc ggcgcggccg acgcgcggac
    25561 actcgacctc acggccctgc gactgcgcac cgtgagcacc accgaatcgg tcacccaccg
    25621 gcttccgtcc ggcccccggc ccctgccccc cggcacctgg gtgctgtccg cgggagacga
    25681 gacaccggcg gtcctcggct gggacccgcc gccggagccc gtcccggccg acggccgcga
    25741 gacgctggtc tgggcgtggt ggctcgcccc ggaggcggcc cgccgagcgg acggggcagg
    25801 acccgagccg gacgcggtcg cagagcgcgg cgtacgggga cacgacccgg agacgcccga
    25861 tcgcgcggtg gcccgtctgg gcgagctcgt caccgagtgg gcgggtggca ccgtttcggc
    25921 cgccggccgc gccggcaggc cggcccccgc cccgcgcgtc ctgcgggtgg acgccggtga
    25981 actgtgccgc ctggtggacc cggagctgga ccgtacgacg gtgactgccc tgctgacggc
    26041 aggggaagcg gcggtccgtg cggagggcga cctgctgtat gtcaccgtcg gcgccgggcg
    26101 cccggacctc gactgcgtgg ccgcgctggc cggtgacgcg gcccgtgtgc gcggctaccg
    26161 gaccgtgccc cgccggctgc cgccctcgtc ggcgggaccg tggccggacc cagaacgcct
    26221 gctgcgcgac gcactcacca ccaccgccct gcgccggggg ttgcagcagg tcgtgacgcc
    26281 cgtgctgctc aggtcgtcgg agccgctcac ccggctcgga gtggcacccg gcgcggagcc
    26341 catcgccgtg cgcgggcgcg ccgggctgcg cgacatgcgg gtgcgcggct ccctgctgcc
    26401 gggcctcctc ggcgtcgccg gccgctcact gcaccagacc ggcgccgccc aggtcttcga
    26461 actcggtcag gtcccgctgt ccgccacgcc ccacgacgag acctggcggt tcgccgtcgt
    26521 cctgagcggt gcctcgacgc ccgcgtcact ggtcgaaccc cggccgcgga ccgtgggctt
    26581 cgccgatctg accggccttc tgcgggcggc cgcgggcgcg gtgggccagg aagcgccgga
    26641 gctgacccct cagccgtatg ccggcttcgt ggccggtgcc tccttcgcgg tgcgcctcca
    26701 gggcggcacg gtgggccggg ccggactgct ctccgaggag aacgcgaccc tgctcgacgc
    26761 gccgggtgag cgcctgttct gcgccgaact cgatctcacg gcgctcggcg gtctcccgcc
    26821 ggttccggtg gcggtgcggg tgccggagcc gctgcccctg cccgcgttca acgtcaccgt
    26881 cgtggtgccc gaggcggtgt cggcggggga cgtgctgcgg gtggtcgccg aggcgggccg
    26941 caccgaacgc gcacgggtca cggtgaagga cctgttgcgg ggcgggcggg tgcccgccgg
    27001 tcaactctcg ctcaccgtgc gggcggagtt cgccggggcg gacgcgggcc cggtccggga
    27061 agaacggcgg cgccgcagag aagccgtgct gcgggcgctc ggcgaccgtg gctggagcgg
    27121 acagtgacag ggccgaccac accgggccac gagggcgccg aagacgcggt cgagctgttc
    27181 accgagtggc tgcggagcga cgggttcacc tgcctgggag cgcgggcggc cctgcaccgc
    27241 ggggaactgg tgaccggtgt ctaccccgct ctggccagtg ccgagtgcct gcccgaactg
    27301 gcgtcggacc tggggcggtt catcaccggc ccgctgagca cggacggacg cttccattcc
    27361 ttcgccgcga tcttcaccga gtgcgatccc ccggacccgg acgaggagac gttcgagcag
    27421 ctgctctggc ggcagttgcg cgcactccac gaagcggacc gcaccgacaa cgtctgggcc
    27481 catgacgtct cggacgatcc acgcagcccc gacttcgggt tcagcttcgg cggccacccc
    27541 ttcttcgtca tagggctgca cccgggggcg tcacgcgtct ccaggcgctt cgcccggccg
    27601 gccctggtct tcaattcgca ccgtcaattc gccgaattga aacgcgccgg cgtgtatcag
    27661 ggaatgcaga cgaagatacg ggccaaggag agggaactcc agggcgatgt gaatcccatg
    27721 ctggcggagc acggagtgat ttccgaagcg cggcagtact ccggccgtat cgtcccaccc
    27781 gactgggaat gcccgttcag tcggcccggc tgacatcggc cgtcgcggcg cgtgcggggc
    27841 gccggtagcg cccggtgacc tcgacgaggt aaccccgcag catggtcttc gcctcgccga
    27901 ggagggcggc gtcgccctcg gggtcgcggc ggaacgcctc ctgggcgagt gcgtcggcgg
    27961 ccaggaacgc ggcgtgacag gcccggccca gggcctcgtc gtcctcggcc aggccgagcg
    28021 ccagcagaac gcggcggacc ccgtcggcca tttggcgctt gtgctcgcgg tccgccgccc
    28081 tggtccgctc ggtcagaccg ctgccgaacc acagcgcccg gaagccgtgt tcggtgcggt
    28141 agaccgcggc acaggcgtcg atcagcacgc cgaccgggtc gtcccagttc tcgtcggccg
    28201 cggcccgggc gaagtcctcc atgaccgctt cgagccgggc gaagtatccg cccgccaggg
    28261 cgtcgatgat cgcgtcgcgg tcgggcaggt actggtacag cgagccgacc gacacctgcg
    28321 cctccgccgc gacgcgcgtg gtggtcagcg cctcgacgcc ctcggagacc agaacccgct
    28381 cggcggcctc cagaacccgg gccaggcggg ccttgctgcg cgcctgccgg ggagtgcggc
    28441 gcagcggggt gacaccacca ccggcccggc cggtgtccgt ggtcggttcg cccacgcatg
    28501 gcctccgaag ctgaacgtga ctttgtttca ggtttacgtt agcgtcgcgg acatgacgga
    28561 ctcaagctcc gcgctgggcc tggagagagc cgccgtcgcg gacgcctgcc gccgtctggg
    28621 tgcggcggga ctgctgatcg gtacggccgg aaacgtcagt gtgcgggtgg gggagcgggt
    28681 cgcggtcacc gcgaccggag cggtgctcgc ccagttgacc gccggtcagg tgagcgtggt
    28741 cgacctggac gggaaggtcg tggccgggac cctgcggccg acctccgaac tggagctgca
    28801 cctcggtgtc taccggcgct acggcgccgg cgcggtcgtc cacacccacg ccccgatggc
    28861 caccgccctg tcctgcgtcc tggacgaact gccctgcatc cactaccagt tgctcgccct
    28921 cggcggcagc gtccgggtgg ccccgtacgc cacgttcggc accccggaac tcgccgagtc
    28981 ggtgctcggg gcgctggagg gccgcagtgc cgccctgatg gccagtcacg gggcgctcac
    29041 ccacggcccg acgctcgaca aggcggtcga gcacgccctg ctgctggagt gggcctgcgg
    29101 cgtctatcag cacgcggccg ccctcggcac tccccgtgtc ctcgacgaac agcagcagcg
    29161 cgcggtgatc gaggccgcga tcgtacgcaa ctacggcacc acccagtccg taccacccgc
    29221 gcaggaggga aaccgatgaa
//
