LOCUS       BGC0001960             34352 bp    DNA     linear   BCT 22-MAR-2019
DEFINITION  Streptomyces hiroshimensis strain A18 hiroshidine biosynthetic gene
            cluster, complete sequence.
ACCESSION   BGC0001960
VERSION     BGC0001960
KEYWORDS    .
SOURCE      Streptomyces hiroshimensis
  ORGANISM  Streptomyces hiroshimensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 34352)
  AUTHORS   Moon,K., Xu,F., Zhang,C. and Seyedsayamdost,M.R.
  TITLE     Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in
            Actinomycete Bacteria
  JOURNAL   ACS Chem. Biol. (2019) In press
   PUBMED   30830740
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 34352)
  AUTHORS   Moon,K., Xu,F., Zhang,C. and Seyedsayamdost,M.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2018) Chemistry, Princeton University, Frick
            Chemistry Laboratory 333, Washington Road, Princeton, NJ 08544, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: unicycler v. 0.4.4
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            ##antiSMASH-Data-START##
            Version               :: 8.dev-5707d64f
            Run date              :: 2025-08-15 20:37:45
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..34352
                     /collected_by="Princeton University"
                     /collection_date="08-Feb-2018"
                     /db_xref="taxon:66424"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces hiroshimensis"
                     /strain="A18"
     region          1..34352
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     subregion       1..34352
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001960"
                     /subregion_number="1"
                     /tool="antismash"
     cand_cluster    1..34352
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..34352
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[18647:21148](-)"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="7 (Score: 724.0; E-value:
                     9.4e-221)"
                     /t2pks_molecular_weights="acetyl-CoA_7 (Da): 506.541"
                     /t2pks_product_classes="benzoisochromanequinone"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      complement(18648..21148)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="7 (Score: 724.0; E-value:
                     9.4e-221)"
                     /t2pks_molecular_weights="acetyl-CoA_7 (Da): 506.541"
                     /t2pks_product_classes="benzoisochromanequinone"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     gene            complement(254..1222)
                     /gene="hrsA1"
     CDS             complement(254..1222)
                     /NRPS_PKS="Domain: NAD_binding_4 (4-224). E-value: 8.8e-18.
                     Score: 56.2. Matches aSDomain:
                     nrpspksdomains_hrsA1_NAD_binding_4.1"
                     /codon_start=1
                     /gene="hrsA1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /note="dTDP-glucose 4,6-dehydratase"
                     /product="HrsA1"
                     /protein_id="QBK46619.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.4e-19, bitscore:
                     59.5, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.6e-20,
                     bitscore: 62.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4.2e-18, bitscore:
                     56.2, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLVTGGAGFIGSHYVRTMLSGGYRGYEDAHVTVIDKLTYAGNT
                     DNLPMGDPRLTFVRGDVCNQDLLRQLLPGHDAVVHFAAESHVDRSVDGAVAFVHSNVLG
                     TQSVLDACLYTGVDNVVHVSTDEVYGSIATGTWTEESPLLPNSPYSASKAGSDLLARAY
                     HRTHKLNVRITRCSNNYGTHQHVEKLIPQFVTRLLQGQQVPLYGEGTNIREWLHVDDHC
                     RAIQLVLTAGRAGETYNIGGATALTNREMTERLLDLTGHDWSKVQHVPDRKGHDFRYAI
                     NDDKIRAELGYAPQWTLDEGLKRVVGWYVDHPEWWKPLLDD"
     misc_feature    254..31766
                     /note="hiroshidine biosynthetic gene cluster"
     aSDomain        complement(551..1210)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsA1_NAD_binding_4.1"
                     /evalue="8.80E-18"
                     /label="hrsA1_NAD_binding_4.1"
                     /locus_tag="hrsA1"
                     /protein_end="224"
                     /protein_start="4"
                     /score="56.2"
                     /tool="antismash"
                     /translation="VTGGAGFIGSHYVRTMLSGGYRGYEDAHVTVIDKLTYAGNTDNLP
                     MGDPRLTFVRGDVCNQDLLRQLLPGHDAVVHFAAESHVDRSVDGAVAFVHSNVLGTQSV
                     LDACLYTGVDNVVHVSTDEVYGSIATGTWTEESPLLPNSPYSASKAGSDLLARAYHRTH
                     KLNVRITRCSNNYGTHQHVEKLIPQFVTRLLQGQQVPLYGEGTNIREWLHVDDHCRA"
     gene            complement(1219..2298)
                     /gene="hrsB"
     CDS             complement(1219..2298)
                     /codon_start=1
                     /gene="hrsB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /note="glucose-1-phosphate thymidylyltransferase"
                     /product="HrsB"
                     /protein_id="QBK46620.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.6e-15, bitscore:
                     46.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVLSGGEGTRLRPFTYSMAKQLVPVANKPVLVHCLENLRDIG
                     IEDVGVIVGGHAAQIEATVGDGSRLGLRLTYIRQEAPLGLAHCVALAADFLGDDDFVMY
                     LGDNVLADGIAEAAEAFHERRPDAQVLVTKVADPRQYGVAEVDADSKVLALVEKPSAPR
                     SDLAVIGVYFFTAAVHEAVRAIEPSARGELEITDAIQHLVDAGRTVTAREYEGYWKDTG
                     KIDDLLECNREILARIAGTAADREGAEVDAESILQGPVVLGPGARVVRSKLTGPLVIGA
                     GSVITGSSVGPYTAVGRDCVLEDSGVEDSIILEGAAIKNVRDLQSCVIGRWAQVQKPVT
                     AASGSRLIIGDHTRAEVMA"
     gene            2442..3296
                     /gene="hrsC"
     CDS             2442..3296
                     /NRPS_PKS="Domain: oMT (39-177). E-value: 1.7e-39. Score:
                     127.1. Matches aSDomain: nrpspksdomains_hrsC_oMT.1"
                     /codon_start=1
                     /gene="hrsC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     (Score: 40.7; E-value: 3.7e-13)"
                     /gene_kind="biosynthetic-additional"
                     /note="O-methyltransferase"
                     /product="HrsC"
                     /protein_id="QBK46621.1"
                     /transl_table=11
                     /translation="MTEQTRAQAEEQQAQALSPDEVGEVYDEKGWLWEIFMGQNLHIGW
                     WDDEAPGVDPKDRLTDVLIEQVALRPGQHLLDIGCGQGRPALRLAEASGGEVTGITVSA
                     EQVSAGTEAAAGAGLADRVRFALADVSELPYADGEFDAAWAMESLMYLGDRPAALREIA
                     RVLKPGGVFVLSDYVESAELDEEWRKVLLEGFTVGSLPTADQYVEMITAAGLTVERNFD
                     ATAHLRRSAARIDQLVADNYDKVVEKGGVQFAEEFKEMIDRVSKLERDMLGYSVITVRK
                     PLA"
     aSDomain        2559..2972
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsC_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.70E-39"
                     /label="hrsC_oMT.1"
                     /locus_tag="hrsC"
                     /protein_end="177"
                     /protein_start="39"
                     /score="127.1"
                     /tool="antismash"
                     /translation="NLHIGWWDDEAPGVDPKDRLTDVLIEQVALRPGQHLLDIGCGQGR
                     PALRLAEASGGEVTGITVSAEQVSAGTEAAAGAGLADRVRFALADVSELPYADGEFDAA
                     WAMESLMYLGDRPAALREIARVLKPGGVFVLSDY"
     gene            3407..4504
                     /gene="hrsD"
     CDS             3407..4504
                     /codon_start=1
                     /gene="hrsD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_functions="biosynthetic-additional (t2pks) GT (Score:
                     375.4; E-value: 9.9e-115)"
                     /gene_kind="biosynthetic-additional"
                     /note="glycosyltransferase IroB"
                     /product="HrsD"
                     /protein_id="QBK46622.1"
                     /sec_met_domain="MGT (E-value: 6.4e-99, bitscore: 322.6,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFGIVPLAQAARNAGHEVFMAAPENMMATITGAGIPGVPVSDVP
                     MMDHLVDRRGIRVPIPEDLHERYIFNGRTFGRYAAACLDGLLSLVADWRPDVVVGGALA
                     FAAPLIAGHLGVPYVKQAIDMGEPRTIDLAAAAELGPELERLGMYEMPRTDLFIDICPP
                     SLRPSDALPAQMMRYVPFATQMPVEPWMYTKGDRPRVLVSAGSRVTPESDFDILSGLVD
                     KVGKLDVELLIATPEAVAEKLRPLPDHVRAGWIPLHLVAPTCDLVVHHAGGNTTMGYLS
                     YGVPQVLVPYLPYCVDYSTRLSAYGAATMIDPADDSAENIARVCAEMLATPSYRERAAE
                     LAAEVSALPTSADAVRAIERLAAAA"
     gene            4565..5722
                     /gene="hrsE"
     CDS             4565..5722
                     /NRPS_PKS="Domain: Aminotran_5 (35-161). E-value: 3e-11.
                     Score: 34.8. Matches aSDomain:
                     nrpspksdomains_hrsE_Aminotran_5.1"
                     /codon_start=1
                     /gene="hrsE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /note="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /product="HrsE"
                     /protein_id="QBK46623.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5.2e-97,
                     bitscore: 316.2, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.9e-09, bitscore:
                     26.0, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 2.5e-11, bitscore:
                     34.0, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINLFQPQVGDAELAAVAEVFDSKWLGHGPRTKAFEAAFAERLGV
                     AAEHVLFVNSGTAGLFLALEVLDLAEGDEVVIPSMSFLAAANAIVSTGATPVFCDVDPR
                     TMNPTWEHIEAAVTPRTKAVVVLHYGGCPGDVVEIAERCRERGLALVEDSACSVDSRVD
                     GRAAGSFGDLAMWSFDAAKVLVTGDGGMLYVRDAERAQRARRLAYHGLVQATGLAYAKV
                     SHRWWELEVPEVGRRVIGNDLTAAIGLVQLGRLPEFTGRRKEIVALYDRELAGVEGVKT
                     PPPLPAGHESSHYFYWVQMDARIRDQVASDLLAADIYTTFRYAPLHKVPTYKSGADLPG
                     TEQASGETLCLPIHPGLADADVLTVVAELRKAIETRTRDLAPAAG"
     aSDomain        4670..5047
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsE_Aminotran_5.1"
                     /evalue="3.00E-11"
                     /label="hrsE_Aminotran_5.1"
                     /locus_tag="hrsE"
                     /protein_end="161"
                     /protein_start="35"
                     /score="34.8"
                     /tool="antismash"
                     /translation="EAAFAERLGVAAEHVLFVNSGTAGLFLALEVLDLAEGDEVVIPSM
                     SFLAAANAIVSTGATPVFCDVDPRTMNPTWEHIEAAVTPRTKAVVVLHYGGCPGDVVEI
                     AERCRERGLALVEDSACSVDSR"
     gene            5749..7014
                     /gene="hrsF1"
     CDS             5749..7014
                     /codon_start=1
                     /gene="hrsF1"
                     /note="hypothetical protein"
                     /product="HrsF1"
                     /protein_id="QBK46624.1"
                     /transl_table=11
                     /translation="MRLLFMSPLAKTLHETTIGLDLADQLKDAGVVSHFVIDEFNEDQL
                     KTAGYAYTVITPAMGGRVREEVARVVGEFRPDAIVLSDYLAHWLTHLVSYETDPWYVED
                     FGVPVIPIDLHDLTNITRELEVLGRTVVADGNILDMPVHLHPVPMGRPEARAGGQGLPY
                     RANRGIEPLTDAARAEVRRSLGLGGAERLLMFPTLPWQETMQTRAGPRTRELAVRVPRL
                     IGHYLRRLPDDTHFVVAGPYLDGLGLPPERVHVEPSYTAQRYHALVGASDAVMSAFLPS
                     YALERAVLADVPGLFALNTHDMGEAAGDGGRAGAPDGLSPVVREWLADFPGAVPAFHMW
                     PLSWNKVMGPLLVDNPFADTAVRTELFDERAVVEGLTGILHDPLVRGRLAEARAAYRDG
                     IDRLPETAEVFATAARRVGLTL"
     gene            7108..8418
                     /gene="hrsA2"
     CDS             7108..8418
                     /codon_start=1
                     /gene="hrsA2"
                     /note="NDP-hexose 2,3-dehydratase"
                     /product="HrsA2"
                     /protein_id="QBK46625.1"
                     /transl_table=11
                     /translation="MFRQTSEFHDWFAEQRAAQDHRVTPAPLRGLDGWSFEPGTGDIRH
                     RSGRFFSIEGIAAETDNREVAAWSQPIIVQPESGILGILVKEFAGVPHFLLQVKMEPGN
                     INILQLSPTVQATRSNFTRVHQGNAVPYLEHFLAPRSGRVIFDALQSEQGSWFLGKRNR
                     NMIIEADGDVPVRDGFCWLTLDQIGELLNVENLVNMDTRTVLSGLPDGWAVQGRSTGAE
                     GRALHGTAALLSWFTEAKASHRLDRRRIPLAEVGGWGESDGAVVHDSGRFFKVIGVDVE
                     AQGREVARWSQPMIAPVGRGVIAFLTRRIEGTVHLLVNARTEAGSFDVLEMGPTVQCAP
                     ANYEGLPAGSRPRFLDEVLSAAPERVLLDVVHSEEGGRFYHAENRYLAVEAPDGFPLEV
                     GPDHIWMTPHQLGAMVRHSHHVNVEARNLLACLRFLR"
     gene            8415..9470
                     /gene="hrsA3"
     CDS             8415..9470
                     /codon_start=1
                     /gene="hrsA3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /note="NDP-hexose 3-ketoreductase"
                     /product="HrsA3"
                     /protein_id="QBK46626.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 6.2e-27, bitscore:
                     85.6, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 2.9e-28,
                     bitscore: 89.3, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAERDPATRTVRLGLMGCADIALRRMLPAVARTGGIALTAVAA
                     RDTARAAQVAQQYGAEAAAGYAELLERDDVDAVYVPLPSALHAEWTERALLAGKHVLAE
                     KPLTPDAAETARLVDLARSRGLVLMENFMFVHHPQHRRVRQLLDEGAIGDVRTVHAAFA
                     VPPRPDGDIRYRADLGGGALFDVGVYPLRAAQLLLGPGLEVVGADLRTDPERGVDVAGS
                     VLLRRHDGVTAHLTFGMEHHYTSRYEVLGSAGRLRLDHAFTPPADHRPVVVVERHGGVE
                     ELELEPFDQVTAAVRALVTSIGSGAGTTTGEATVRHAELVADVHRAGHARRGRAGTARR
                     LAEYAVGGEEK"
     gene            9467..10765
                     /gene="hrsA4"
     CDS             9467..10765
                     /codon_start=1
                     /gene="hrsA4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /note="NDP-hexose 3,4-dehydratase"
                     /product="HrsA4"
                     /protein_id="QBK46627.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.9e-104,
                     bitscore: 340.1, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEAKARILEQVREYHGSDEKEFVPGETGVWPAGAVFDADDRVAL
                     VEAALDMRIAAGVSSRRFERQFAKYFKLRKAHLTNSGSSANLLALSAFTSPQLEDRRLQ
                     PGDEVITVAAGFPTTVNPIIQNGLVPVFIDVELGTYNTTPERIAEAIGPRTKAIMIAHS
                     LGNPFAVEEVAKLAEEHDLFLIEDNCDAVGSLYRGKPTGTFGDIATTSFYPAHHLAMGE
                     GGCVLTDNLALARIVESMRDWGRDCWCEPGEDNRCFKRFDYQMGDLPHGYDHKYIFSHV
                     GYNLKATDLQAALGLSQLSKIDAFGAARRANWKRLREGLDGVPGLLLPEATPDSDPSWF
                     GFAITVRPEARYTRKDLVAFLEARKIGTRRFFAGNLTRHPAYLDRPRRISGSLANSDLV
                     AEHTFWIGVYPGLTPEMIDYSAESIRDFAAKNS"
     gene            10870..12012
                     /gene="hrsG"
     CDS             10870..12012
                     /codon_start=1
                     /gene="hrsG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /note="hydrolase"
                     /product="HrsG"
                     /protein_id="QBK46628.1"
                     /transl_table=11
                     /translation="MTREAAAAAPTLLEAAVAAAPLAAAHAADAEADRRLSPPVVEAIV
                     AAGFSGHFAPAALGGAAGTFAELLDASAALGEGCASAAWFASVIASAGRLTAYLPREGR
                     EGVWAKGPQTVVVAGLMPSGTAERAPGGGWRVTGSWNYVSAVDFSDWTLIAARTGEQGT
                     GVRVLAVPRTDYAISETWQVIGMRGTGSNTVVLDEVLVPDAFTVPLDVLLAGLAPEAEA
                     ACHRVPMKAANGVTLAGPLLGATRGALRRWRELVAAKLAAPAGAISGGSDHGTFEQLLA
                     RAEGEIDAAGLLLERVARTTDSGAVDGLGTARNGRDCALAAEMLATVSDRLLRSAGTRA
                     QAEGEELQRRWRDVNCGAGHSGLQFPAAAGAYARLLNASA"
     gene            complement(12143..12946)
                     /gene="hrsH"
     CDS             complement(12143..12946)
                     /codon_start=1
                     /gene="hrsH"
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /note="SARP family transcriptional regulator"
                     /product="HrsH"
                     /protein_id="QBK46629.1"
                     /transl_table=11
                     /translation="MRFNLIGPFEIVTGDGRPPHLPSTPKVCQTLALLLTRPNEIVTSE
                     SLIQELWGESPPRSALTTLQTYIYHARKMFIAERLVPAERALLITQPPGYLIRVEDHEV
                     DIKIFERLVLQGKTALENGRPEAAVQRLEQALALWRGPALSNIPAGDVLTGRIVHLNEL
                     RIRALELRIEAELQLGRQRESIPLLRALVNDYPLNEWFHGQLISALNHSGRRAEALQAY
                     QSLRRILNDELGLEPSPELQRLQLDVLNPSETVPAQRRRLVPAGL"
     gene            complement(13117..14037)
                     /gene="hrsI"
     CDS             complement(13117..14037)
                     /codon_start=1
                     /gene="hrsI"
                     /gene_functions="resistance (resist) ClassB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C5-C14
                     (Score: 505.4; E-value: 1.1e-154)"
                     /gene_kind="biosynthetic-additional"
                     /note="cyclase"
                     /product="HrsI1"
                     /protein_id="QBK46630.1"
                     /transl_table=11
                     /translation="MNTRNTHDTPRLQEVAENVHAYIQPDGGWCLNNAGLIVGGNRSAL
                     VDTAATEARARALKEAVAPLTARPPQFVVNTHSHGDHTFGNYLFADDAVVVSHERTRTE
                     MADIGLHLTGLWPEVCWGDVSVELPTLTFRDRLTLHIGDVTAELLHPGIGHTTNDTVVW
                     LPEQRVLFTGDLVMSGATPFCLMGSVSGSLAVTEQLRALDPVTVVAGHGPVGGPELLDT
                     TEGYLRRVQEIARAGLAAGIGPLEAAREADLGEYAELLDSERLVPNLHRAYAEEKGAPP
                     GRPLDIGLLFSEMIEYHGGLPACHA"
     gene            complement(14074..14949)
                     /gene="hrsJ"
     CDS             complement(14074..14949)
                     /NRPS_PKS="Domain: ACPS (139-201). E-value: 3.2e-12. Score:
                     38.4. Matches aSDomain: nrpspksdomains_hrsJ_ACPS.1"
                     /codon_start=1
                     /gene="hrsJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /note="4-phosphopantetheinyl transferase"
                     /product="HrsJ"
                     /protein_id="QBK46631.1"
                     /transl_table=11
                     /translation="MATSGPRGLAGSAPVRVTAPDGPWTATDTAMDERGFALLYGLMAD
                     WGEHGLPDDELGRLLGQEAGRHAGIRQERTRRRFAASRLLLKYAAGAVLDADPGELELA
                     RNPNGRPYLRGCGQLEVSLSHTGDILAVGLSHVGPIGVDVESSARSIYGTGLAEESFTA
                     YERAALGWLPEQDRNASMIRLWTLKEAYSKALGLGLRLPFTSFGFTIPAASGATARLLR
                     SDGSPADDGDWHLESHTLDAGYTVSAAVAPAVFGTARRPTAGTVLDAGLAAAVLAARPP
                     RPALDPRSPQ"
     aSDomain        complement(14347..14532)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsJ_ACPS.1"
                     /evalue="3.20E-12"
                     /label="hrsJ_ACPS.1"
                     /locus_tag="hrsJ"
                     /protein_end="201"
                     /protein_start="139"
                     /score="38.4"
                     /tool="antismash"
                     /translation="IGVDVESSARSIYGTGLAEESFTAYERAALGWLPEQDRNASMIRL
                     WTLKEAYSKALGLGLRL"
     gene            complement(15004..16776)
                     /gene="hrsK1"
     CDS             complement(15004..16776)
                     /codon_start=1
                     /gene="hrsK1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /note="acyl-CoA dehydrogenase"
                     /product="HrsK1"
                     /protein_id="QBK46632.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.5e-09, bitscore:
                     27.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSSDIGSLSEAVPSAVPSADRVAALERRLGDPLDPGNPLGHAA
                     ALAADRRGELPLGGEPLLDAFGLREEIVPQRLGGRLTGLDTATQLLRAVFRRDFALGRG
                     HGSASLVSAVFAWCHGTPEQQARTARLLLDGGRLSVAFQNMSYGNEFSSGDLTLTPAPQ
                     GGGVLDGRTPLIANAPLAAGFVLLARHADGDGAHSALLLDRADLPPDAVRLLSPYDATA
                     VRRLPAGFLEFVRWPVPAGSVLGAPGDGTAVALRSLQVSRPLVPSMAVGCADTALRSVV
                     AAVLERAPGVRPLTSRYARRAITSSFADMLVCDCLLLAAIRSLHLLPEESSVWTAAAMC
                     LVVRMLQQSTGDLAAVLGPRALQEDGGFGTFRKHLRDLSEIPPGPIGAAAALATLVPQL
                     PFLARTSWTAATPPPGLFSTSAPLPPLDPGRLDLAAGGDTLMAVLPHAEAALDTLPVTG
                     PDGEALRSQVRALAAELRALGEECRALPEQDLAALATPHGYALAERYTLLAAAAACLGV
                     WLHGDREREAGFLSDPAWLIAALGRVQFRLGLPEPAADDRRGEALLAAVVERCTQGRSL
                     DLYDVLLGGGPAAA"
     gene            complement(16760..17188)
                     /gene="hrsK2"
     CDS             complement(16760..17188)
                     /codon_start=1
                     /gene="hrsK2"
                     /note="hydroxylacyl-CoA dehydrogenase"
                     /product="HrsK2"
                     /protein_id="QBK46633.1"
                     /transl_table=11
                     /translation="MTATQSLTELHSQVQHFYAHQMHHLDARRFEEYAATFTEDGVFQH
                     SPGAEPAVGRPGIVEELVNFHKKFDGDPVTRRHWFNQIALDPQDDGTVKSTVYALVVTV
                     RPGGKPEINPSCTVHDTLVVNGGEVQLKSRLITHDQVF"
     gene            complement(17262..18266)
                     /gene="hrsI2"
     CDS             complement(17262..18266)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (20-163). E-value:
                     5.5e-13. Score: 41.5. Matches aSDomain:
                     nrpspksdomains_hrsI2_Polyketide_cyc2.1"
                     /codon_start=1
                     /gene="hrsI2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 447.7; E-value: 3.8e-137)"
                     /gene_kind="biosynthetic-additional"
                     /note="cyclase"
                     /product="HrsI2"
                     /protein_id="QBK46634.1"
                     /transl_table=11
                     /translation="MPGPGPVRTEETNDMTEPRRHHTEHTLDVSAPPEVLYGLVADVTT
                     WPAIFGPSVHVHHLERGERAERFEIWATVNGKVSTWTSRRTLDPEALRVTFRQERSTAP
                     VASMGGEWIFEALPGGGTRVVLLHDFTAVGDAPETVAAVNAALDRNSPEELAALARIAE
                     YGGTASDVVFSFTDTVELTGSAADAFDFVDRADLWAERLPHVRQARLTEDVPGIQDLEM
                     DTVTADGSAHTTRSTRICRGPEWIAYKQHVMPKLLLGHSGLWHFADKPGGGAVATARHT
                     VAVNPEAVTEVLGAGATLADARAYLREALGRNSLATMAHAATYAEQRAAAQAG"
     aSDomain        complement(17778..18206)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsI2_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.50E-13"
                     /label="hrsI2_Polyketide_cyc2.1"
                     /locus_tag="hrsI2"
                     /protein_end="163"
                     /protein_start="20"
                     /score="41.5"
                     /tool="antismash"
                     /translation="HHTEHTLDVSAPPEVLYGLVADVTTWPAIFGPSVHVHHLERGERA
                     ERFEIWATVNGKVSTWTSRRTLDPEALRVTFRQERSTAPVASMGGEWIFEALPGGGTRV
                     VLLHDFTAVGDAPETVAAVNAALDRNSPEELAALARIAE"
     gene            complement(18326..18589)
                     /gene="hrsL"
     CDS             complement(18326..18589)
                     /NRPS_PKS="Domain: PP-binding (7-77). E-value: 9.1e-15.
                     Score: 47.0. Matches aSDomain:
                     nrpspksdomains_hrsL_PP-binding.1"
                     /codon_start=1
                     /gene="hrsL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 116.7; E-value: 8.3e-37)"
                     /gene_kind="biosynthetic-additional"
                     /note="acyl carrier protein"
                     /product="HrsL"
                     /protein_id="QBK46635.1"
                     /sec_met_domain="PP-binding (E-value: 4.4e-15, bitscore:
                     47.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHMTVDDVRRILVECAGVDDSIDITGDISDRPFDELGYDSLALM
                     ESAAQIKQEFGVVVPDDELVEVETPRALIDLVNGLVTEAAAA"
     aSDomain        complement(18359..18568)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsL_PP-binding.1"
                     /evalue="9.10E-15"
                     /label="hrsL_PP-binding.1"
                     /locus_tag="hrsL"
                     /protein_end="77"
                     /protein_start="7"
                     /score="47.0"
                     /tool="antismash"
                     /translation="DVRRILVECAGVDDSIDITGDISDRPFDELGYDSLALMESAAQIK
                     QEFGVVVPDDELVEVETPRALIDLV"
     gene            complement(18648..19883)
                     /gene="hrsM2"
     CDS             complement(18648..19883)
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (12-367). E-value:
                     5.6e-30. Score: 96.5. Matches aSDomain:
                     nrpspksdomains_hrsM2_PKS_KS.1"
                     /codon_start=1
                     /gene="hrsM2"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 7
                     (Score: 724.0; E-value: 9.4e-221)"
                     /gene_kind="biosynthetic"
                     /note="chain length factor, beta-ketoacyl synthase beta
                     subunit"
                     /product="HrsM2"
                     /protein_id="QBK46636.1"
                     /sec_met_domain="t2clf (E-value: 6.7e-205, bitscore: 671.2,
                     seeds: 26, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.5e-44, bitscore:
                     142.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 4.6e-24, bitscore: 75.9,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 8.5e-27, bitscore: 84.8,
                     seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 2.1e-23, bitscore: 73.7,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 1.5e-27, bitscore: 87.3,
                     seeds: 217, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSKDGLNGRTVITGIGVTAPNGLGTEAFWKAVLAGHTGIGPVTR
                     FDASRYASSLAGQIDDFDAAEHLNSRLLPQTDPSTRLALVAADWALTDAGVSPDTLPDY
                     DMGVVTSNAMGGFDFTHREFDKLWNKGPDFVSVYESFAWFYAVNTGQISIRHKLRGPSA
                     ALVGEQAGGLDALGHARRTVRRGTPLVVAGGVDSALDPWGYVSQLAGGRVTTATDPARA
                     YLPFSADASGYVPGEGGAILVAEDEASARERGAQQVYGELAGYAATFDPAPGTGRPPAL
                     RRAAEAALADAGLAPGDIDVVFADGAGVPGLDAAEAAAISGVFGAGAVPVTAPKALTGR
                     LYSGGGPLDVATALLSIRDGVIPPTPTGAPVPEAYGLDLVRGAPRDQRVRTALVLARGR
                     HGFNSAVVVRAA"
     aSDomain        complement(18783..19847)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsM2_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="5.60E-30"
                     /label="hrsM2_PKS_KS.1"
                     /locus_tag="hrsM2"
                     /protein_end="367"
                     /protein_start="12"
                     /score="96.5"
                     /tool="antismash"
                     /translation="ITGIGVTAPNGLGTEAFWKAVLAGHTGIGPVTRFDASRYASSLAG
                     QIDDFDAAEHLNSRLLPQTDPSTRLALVAADWALTDAGVSPDTLPDYDMGVVTSNAMGG
                     FDFTHREFDKLWNKGPDFVSVYESFAWFYAVNTGQISIRHKLRGPSAALVGEQAGGLDA
                     LGHARRTVRRGTPLVVAGGVDSALDPWGYVSQLAGGRVTTATDPARAYLPFSADASGYV
                     PGEGGAILVAEDEASARERGAQQVYGELAGYAATFDPAPGTGRPPALRRAAEAALADAG
                     LAPGDIDVVFADGAGVPGLDAAEAAAISGVFGAGAVPVTAPKALTGRLYSGGGPLDVAT
                     ALLSIRDGVIPPTPT"
     CDS_motif       complement(19170..19208)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hrsM2_0001"
                     /evalue="3.90E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="hrsM2"
                     /protein_end="238"
                     /protein_start="225"
                     /score="13.5"
                     /tool="antismash"
                     /translation="FSADASGYVPGEG"
     gene            complement(19880..21148)
                     /gene="hrsM1"
     CDS             complement(19880..21148)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (4-395). E-value:
                     9.6e-54. Score: 174.8. Matches aSDomain:
                     nrpspksdomains_hrsM1_PKS_KS.1"
                     /codon_start=1
                     /gene="hrsM1"
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ene_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     780.0; E-value: 1.2e-237)"
                     /gene_kind="biosynthetic"
                     /note="polyketide beta-ketoacyl synthase, alpha subunit"
                     /product="HrsM1"
                     /protein_id="QBK46637.1"
                     /sec_met_domain="t2ks (E-value: 4.2e-246, bitscore: 807.5,
                     seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.5e-56, bitscore:
                     181.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 6.5e-44, bitscore: 141.3,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 6.3e-45, bitscore: 144.6,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.9e-51, bitscore: 166.1,
                     seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 8.5e-44, bitscore: 140.9,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 5.1e-31, bitscore: 98.6,
                     seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRVVITGIGVRAPGGSGTKEFWDLLTAGRTATRRISFFDAAPF
                     RSQVAAEADFFPEAEGFSPREIRRMDRATQFAVACTREAVADSGLEFAGVDPHRVGVSL
                     GSAVASATSLENEYLVMADKGREWLVDPDYLSPHMFDYLSPGVMPAEVAWAAGAEGPVT
                     MVSDGCTSGLDAVGYGVQLIREGSADVMIAGASDTPISPIVLACFDAIKATTTRNDDPE
                     HASRPFDASRNGFVLAEGSAMFVLEEYEAAKARGAQIYAEVTGYATRCNAYHMTGLKKD
                     GREMAEAIRAALDESRVDPTVVDYVNAHGSGTKQNDRHETAAFKIALGQHAYDVPVSSI
                     KSMVGHSLGAIGSIEIAACALAIKHNVVPPTANLHTPDPECDLDYVPLTAREQRVDSVL
                     TVGSGFGGFQSAMILRAPEGVKA"
     aSDomain        complement(19964..21136)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsM1_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="9.60E-54"
                     /label="hrsM1_PKS_KS.1"
                     /locus_tag="hrsM1"
                     /protein_end="395"
                     /protein_start="4"
                     /score="174.8"
                     /tool="antismash"
                     /translation="VVITGIGVRAPGGSGTKEFWDLLTAGRTATRRISFFDAAPFRSQV
                     AAEADFFPEAEGFSPREIRRMDRATQFAVACTREAVADSGLEFAGVDPHRVGVSLGSAV
                     ASATSLENEYLVMADKGREWLVDPDYLSPHMFDYLSPGVMPAEVAWAAGAEGPVTMVSD
                     GCTSGLDAVGYGVQLIREGSADVMIAGASDTPISPIVLACFDAIKATTTRNDDPEHASR
                     PFDASRNGFVLAEGSAMFVLEEYEAAKARGAQIYAEVTGYATRCNAYHMTGLKKDGREM
                     AEAIRAALDESRVDPTVVDYVNAHGSGTKQNDRHETAAFKIALGQHAYDVPVSSIKSMV
                     GHSLGAIGSIEIAACALAIKHNVVPPTANLHTPDPECDLDYVPLTAREQRV"
     gene            21554..22783
                     /gene="hrsN"
     CDS             21554..22783
                     /codon_start=1
                     /gene="hrsN"
                     /note="transposase"
                     /product="HrsN"
                     /protein_id="QBK46638.1"
                     /transl_table=11
                     /translation="MQLSPVSSEEPPFGHPSPADPWDVEPEFFSSLTRNDQRRMAEQYV
                     RGLLEAEGRKTLRNVAEQIGGKALQQSVHHFITASSWNWAPVRRALARRAEEEVRPQAW
                     VVNSTVIPKAGVHSVGVDQQFLPHLGQTVNGQRAFSVWSASERVSVPFNWSLVLSRSWL
                     EDPARRSRAHIPDASRAISLEEHAGAVALEAADSWGLRRRPVVVDVEGLDAGATVRRFA
                     RAGVPLIMRIDGTTPLRVDGALLQGYSDREVPAQNLIGSMKRMRRQVEWSDTSGTGSYR
                     GVVSAIPVVLSCPAPAGVPGGTHHRPMLLMGDWGSSDRWPSRMWLTDSRRLPLVTLLRL
                     TRLTGVVQRDFAEISEHTGIRDFAGRSFRGWHRHVTLASVAHLIAVRAGARRVPAQRRR
                     AAGSAAPLCA"
     gene            complement(22804..23304)
                     /gene="hrsO"
     CDS             complement(22804..23304)
                     /codon_start=1
                     /gene="hrsO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="flavin reductase"
                     /product="HrsO"
                     /protein_id="QBK46639.1"
                     /transl_table=11
                     /translation="MLAETITAERFRTSLARWASGVTVVTTVDAQGRSHGFTASSFTSV
                     SLEPPLVLVCLDLRANCFDAFTGAEGFVVHVLGRDQQDLAALFARRGADKFPRPGMTSS
                     RRGLPLLPGALARLECRTERQVPAGDHLVLFGEVEHAEAGEGEPLLYYRKGFHGIAGPG
                     AAD"
     gene            23520..24305
                     /gene="hrsK3"
     CDS             23520..24305
                     /NRPS_PKS="Domain: PKS_KR (7-162). E-value: 3e-16. Score:
                     51.8. Matches aSDomain: nrpspksdomains_hrsK3_PKS_KR.1"
                     /codon_start=1
                     /gene="hrsK3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 438.1; E-value: 2.3e-134)"
                     /gene_kind="biosynthetic-additional"
                     /note="acetoacetyl-CoA reductase"
                     /product="HrsK3"
                     /protein_id="QBK46640.1"
                     /sec_met_domain="adh_short (E-value: 1.2e-43, bitscore:
                     140.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTQHAKVALVTGATSGIGLAIATHLARNGARVYLCARDAAKLAE
                     TVKSLQDQGFEADGTTCDVTDREDVKRFVAAAVERFGTVDILVNNAGRNGGGAIAEMSD
                     ELWYDVINTNLNSVFLVTREVLSAGGLLTKGWGRIVNIASTAGKQGAVTAAPYSASKHG
                     VVGFTKALGLDLAKTGITVNAVCPGFVETPMAERVRGHYAEMYGITLEEAAEKVTTRVP
                     IGRYVDVEEVAAMVDYLVGDGASSVTAQALNVCGGLGNY"
     aSDomain        23541..24005
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsK3_PKS_KR.1"
                     /evalue="3.00E-16"
                     /label="hrsK3_PKS_KR.1"
                     /locus_tag="hrsK3"
                     /protein_end="162"
                     /protein_start="7"
                     /score="51.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLAIATHLARNGARVYLCARDAAKLAETVKSLQD
                     QGFEADGTTCDVTDREDVKRFVAAAVERFGTVDILVNNAGRNGGGAIAEMSDELWYDVI
                     NTNLNSVFLVTREVLSAGGLLTKGWGRIVNIASTAGKQGAVTAAPYSASKH"
     CDS_motif       23547..23615
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hrsK3_0001"
                     /evalue="5.50E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="hrsK3"
                     /protein_end="32"
                     /protein_start="9"
                     /score="28.6"
                     /tool="antismash"
                     /translation="LVTGATSGIGLAIATHLARNGAR"
     gene            24438..25421
                     /gene="hrsK4"
     CDS             24438..25421
                     /codon_start=1
                     /gene="hrsK4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     129.6; E-value: 3.9e-40)"
                     /gene_kind="biosynthetic-additional"
                     /note="3-hydroxyacyl-CoA dehydrogenase"
                     /product="HrsK4"
                     /protein_id="QBK46641.1"
                     /transl_table=11
                     /translation="MTDSPVGTRIRTAAVIGVGTIGLGWAALFASAGLTVRINSRRPDA
                     EAHVRKAFELYAASLPGGPADPAGLAARLEFEPDVARAVEGADVVQENAPEDLALKQDL
                     FARIGAAAPAHALLLSSTSTLLPDALGARMADPGRLLVAHPFNPPHIVPLVEIVTGERT
                     DPRAVEETVAFYRGLGKTPVVLRRAVPGFVANRLQSALLRESIHLVREGVVSVAELDEI
                     VTSSIGGRWAAVGPFRAFHLGGGPGGLRHWFEHLGAGLEKSWQGLGNPPVDEETVARIL
                     AQAEEAFGGRTYEELAAERDAKQTRVIAAAGTDADAGTDAGPAQRA"
     gene            25682..26593
                     /gene="hrsP1"
     CDS             25682..26593
                     /NRPS_PKS="Domain: PKS_ER (14-231). E-value: 8.2e-39.
                     Score: 125.5. Matches aSDomain:
                     nrpspksdomains_hrsP1_PKS_ER.1"
                     /codon_start=1
                     /gene="hrsP1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /note="quinone oxidoreductase"
                     /product="HrsP1"
                     /protein_id="QBK46642.1"
                     /sec_met_domain="ADH_N (E-value: 2.5e-13, bitscore: 40.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2e-14, bitscore:
                     44.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAVFQEFGGPEVLKVEEVETPRPGAGEIRVRVKAAGVQAYDTA
                     VRAGWNPPGMTISFPQTIGNDFAGVVDELGEGVTEFAVGDEVLGWALLSCSAEYLVVSA
                     EQVVAKPAGMPWEVAGAFSASAQTAHTALEALEIGAGDTLLVHAAAGGVGTIAVQLAQV
                     LGATAIGTASERNHEYLRSLGATPVTYGEGLADRVRELAPGGVTAALDGIGGDALDVSV
                     ELVKDKNRIATLVDFGRVEELGVRAVFSQRAKERLAGLTALYAEGKLRVEVSKTFPLEQ
                     AADAHREMETGHVRGKIVITVG"
     aSDomain        25724..26374
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsP1_PKS_ER.1"
                     /evalue="8.20E-39"
                     /label="hrsP1_PKS_ER.1"
                     /locus_tag="hrsP1"
                     /protein_end="231"
                     /protein_start="14"
                     /score="125.5"
                     /tool="antismash"
                     /translation="LKVEEVETPRPGAGEIRVRVKAAGVQAYDTAVRAGWNPPGMTISF
                     PQTIGNDFAGVVDELGEGVTEFAVGDEVLGWALLSCSAEYLVVSAEQVVAKPAGMPWEV
                     AGAFSASAQTAHTALEALEIGAGDTLLVHAAAGGVGTIAVQLAQVLGATAIGTASERNH
                     EYLRSLGATPVTYGEGLADRVRELAPGGVTAALDGIGGDALDVSVELVKDKNRI"
     CDS_motif       26102..26164
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hrsP1_0001"
                     /evalue="9.20E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="hrsP1"
                     /protein_end="161"
                     /protein_start="140"
                     /score="24.5"
                     /tool="antismash"
                     /translation="GDTLLVHAAAGGVGTIAVQLA"
     gene            26629..27282
                     /gene="hrsQ"
     CDS             26629..27282
                     /codon_start=1
                     /gene="hrsQ"
                     /note="DsbA family oxidoreductase"
                     /product="HrsQ"
                     /protein_id="QBK46643.1"
                     /transl_table=11
                     /translation="MKIEIYSDVLCPWCYIGKRRIAAALDGFAHRDELEIVWRSFELAP
                     GEGSEPGPTAAEAMAEWTAPDVLPGRIELIKSQGRQEGLELNLHKSRPVGTFDAHRLTH
                     FAAERGLLEPVMERLFHAYHTEALNVADREVLVRLAGEAGLDEAEVREVLESDRYADAV
                     VADGNRARQFNVTGVPSVVIDGRMPVSGVQAPEKLLTFIERAWERAHKEPAASV"
     gene            27515..28156
                     /gene="hrsF2"
     CDS             27515..28156
                     /codon_start=1
                     /gene="hrsF2"
                     /note="hypothetical protein"
                     /product="HrsF2"
                     /protein_id="QBK46644.1"
                     /transl_table=11
                     /translation="MQHKWKLTGGLAASLGLALTGIMSSAGTASADTATKTLDYTCQTR
                     VDGNWIPVPYSRDFTTTAPAKVAPGQTFKVTFDSAPIKAVADFNKLLNNVNIAYKTPAN
                     AKVVGYKLTGGSNLGTAKQWVERNGTNFNIKSNGEWAGGVEFDFPNLEVTLKAPTTAGA
                     TLTTGAGGSSFEDTAFGWTRLQTQLNTWDPFQCYADPAKPVAFSTTTVGY"
     gene            28286..30094
                     /gene="hrsK5"
     CDS             28286..30094
                     /codon_start=1
                     /gene="hrsK5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     95.2; E-value: 1.2e-29)"
                     /gene_kind="biosynthetic-additional"
                     /note="3-hydroxyacyl-CoA dehydrogenase"
                     /product="HrsK5"
                     /protein_id="QBK46645.1"
                     /transl_table=11
                     /translation="MMSSAVQPPGDVVQPPGDIVQPPGDVVQPSENAVRPCGERTVVAV
                     IGAGTIGLGWIALFLDRGLRVRVNSRRPDAERVVREGLAVFAPTLPGGAADVGVLMEHV
                     EFEPDMARAVRGAAVVQENAPDDLALKQELFRTVEQAAPAEALLLSSTSKLLPDDMGAL
                     MAEPGRVVVGHPFNPPHVVPLVEVVGGRHTPAALIDEVTAFYRAVGKVPVVVRKPVPRF
                     VANRLQSALLRESVHLVQEGVVTMAELDAVVTQSIGLRWATVGPFEAFHLGGGEGGLRR
                     WLGGVAPGLERAWRAPAVPALTPDAVEALGAEADRTFGTDYAALSRARDEKQNAVLDAL
                     ARIDARPESLREDETMEPQPQPQPQPPSRQTPPPQQGEPHVVDFWFDPLCPFAWITSRW
                     ITEVAGKAPVTVRWHAMSLALLNSGKDMPEARRTMLDLYWGPVRVLAAARAAHGDAVTG
                     PLYTAMGSRFHAPGGIFEPVRTAPAEEFRAAMIEGLGRTRPGIEAALAETGLPAGLIDA
                     MDDDRWDDELRASHARVPSDGLGQELIGVPTISVDGGAGQFGPVLTEIPRGERAVRLWE
                     AFRTLAGDPAFFELKQSTGRTEPLTH"
     gene            30147..31133
                     /gene="hrsP2"
     CDS             30147..31133
                     /NRPS_PKS="Domain: PKS_ER (15-326). E-value: 5.9e-53.
                     Score: 171.9. Matches aSDomain:
                     nrpspksdomains_hrsP2_PKS_ER.1"
                     /codon_start=1
                     /gene="hrsP2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /note="quinone oxidoreductase"
                     /product="HrsP2"
                     /protein_id="QBK46646.1"
                     /sec_met_domain="ADH_N (E-value: 2.2e-07, bitscore: 21.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.9e-30, bitscore:
                     95.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVIRIREFGGPEVMRVEETPVPQPGPGEVLIAAEAISVGFAQTQ
                     MRRNIFPAPMWRPEFPIVLGGDVIGRVAGVGAGVTGFREGDRVGAFTLHGAYADYVVVD
                     AATVLPVPEGLDAAQATALPSPGPIGTGTLGTANLRPGESVLVHAASGGIGHLSVQWAK
                     AHGAGPVIATASSAEKLDFARALGADVVVDYSREGWADEVREATGGAGVDIILDSIGGD
                     VLRQGVGLLAPFGRLVFYGSAGGGLEIPRISPMELIEMKFITGFALSRWRAARPKEYLA
                     NHEELAAGLADGTIRHAVHATYPLEEVGRAHEEIESRAHIGRIVLLP"
     aSDomain        30192..31124
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_hrsP2_PKS_ER.1"
                     /evalue="5.90E-53"
                     /label="hrsP2_PKS_ER.1"
                     /locus_tag="hrsP2"
                     /protein_end="326"
                     /protein_start="15"
                     /score="171.9"
                     /tool="antismash"
                     /translation="RVEETPVPQPGPGEVLIAAEAISVGFAQTQMRRNIFPAPMWRPEF
                     PIVLGGDVIGRVAGVGAGVTGFREGDRVGAFTLHGAYADYVVVDAATVLPVPEGLDAAQ
                     ATALPSPGPIGTGTLGTANLRPGESVLVHAASGGIGHLSVQWAKAHGAGPVIATASSAE
                     KLDFARALGADVVVDYSREGWADEVREATGGAGVDIILDSIGGDVLRQGVGLLAPFGRL
                     VFYGSAGGGLEIPRISPMELIEMKFITGFALSRWRAARPKEYLANHEELAAGLADGTIR
                     HAVHATYPLEEVGRAHEEIESRAHIGRIVL"
     CDS_motif       30234..30272
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hrsP2_0001"
                     /evalue="2.10E+01"
                     /label="PKSI-ER_m5"
                     /locus_tag="hrsP2"
                     /protein_end="42"
                     /protein_start="29"
                     /score="-1.7"
                     /tool="antismash"
                     /translation="VLIAAEAISVGFA"
     CDS_motif       30570..30632
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hrsP2_0002"
                     /evalue="8.10E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="hrsP2"
                     /protein_end="162"
                     /protein_start="141"
                     /score="21.5"
                     /tool="antismash"
                     /translation="GESVLVHAASGGIGHLSVQWA"
     CDS_motif       30765..30800
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_hrsP2_0003"
                     /evalue="1.30E-03"
                     /label="PKSI-ER_m7"
                     /locus_tag="hrsP2"
                     /protein_end="218"
                     /protein_start="206"
                     /score="11.5"
                     /tool="antismash"
                     /translation="TGGAGVDIILDS"
     gene            31161..31766
                     /gene="hrsR"
     CDS             31161..31766
                     /codon_start=1
                     /gene="hrsR"
                     /note="NADPH-dependent FMN reductase"
                     /product="HrsR"
                     /protein_id="QBK46647.1"
                     /transl_table=11
                     /translation="MPDTNAQHPTRLAVIVGSTRKDRFGPVVADWFTAHARERADLDVD
                     VIDLAEADLPHVLEGPGEDGTHPSAAVRAFAARIDRADVFAVITPEYNRGYPAALKQAI
                     DSVYTEFHAKPVGFVSYSGGATGGVRAVEQLRSVFAELHTVTLRDGVAIPSAYAAFDDD
                     GQPRDTEGVNGAAKKLLDQLLWWAVALREARAKSPYAA"
ORIGIN
        1 caggtgtgcc tgatgtgcct ggcgtgcccg gtgtgctcgg tgcacttgtc gtgcccggtg
       61 tgcccgctgt gccgggctct gcggacggcg acgacgggcc ggtgtgcccc tccgtgacgg
      121 acatcaggac gtgctccagg gttgtggctg ctgcagggac gagtgccgtc ctgccactcc
      181 ttcagatgcc gctcgaggat cactcgagcg gcactcgaag acggtggcgc ggattccgcc
      241 aagctgtccg ttctcagtca tcgagcagcg gcttccacca ctccgggtgg tccacgtacc
      301 agccgacgac gcgcttcagg ccctcgtcga gcgtccactg cggcgcgtag ccgagctcgg
      361 cgcggatctt gtcgtcgttg atcgcgtagc ggaagtcgtg gcccttgcgg tccgggacgt
      421 gctgcacctt cgaccagtcg tggccggtca ggtcgagcag ccgctcggtc atctcgcggt
      481 tggtcagggc ggtggcgccg ccgatgttgt acgtctcgcc cgcgcggccg gccgtgagga
      541 cgagctggat ggcccggcag tggtcgtcga cgtgcagcca ctcgcggatg ttggtgccct
      601 cgccgtagag aggcacctgc tgtccctgca ggaggcgggt gacgaactgc gggatgagct
      661 tctcgacgtg ctggtgggtg ccgtagttgt tggagcaccg ggtgatgcgc acgttgagct
      721 tgtgggtgcg gtggtaggcg cgggcgagga ggtcgctgcc ggccttcgac gcggagtagg
      781 gggagttggg gagcaggggc gactcctcgg tccacgttcc ggtggcgatg gatccgtaga
      841 cctcgtcggt cgacacgtgc accacgttgt ccacaccggt gtacagacag gcgtcgagga
      901 cgctctgggt gcccaggacg ttgctgtgga cgaaggccac cgcgccgtcg acggagcggt
      961 cgacgtggga ctcggccgcg aagtggacga cggcgtcgtg gccggggagc agctggcgca
     1021 gcaggtcctg gttgcagacg tcgccgcgga cgaaggtcag ccgcgggtcg cccatcggca
     1081 ggttgtccgt gttgccggcg taggtgagct tgtcgatgac ggtgacgtgc gcgtcctcgt
     1141 agcctcggta gccgccggag agcatggtgc ggacgtagtg cgagccgatg aagccggcgc
     1201 cgccggtgac gaggaccttc atgccattac ctccgcgcgc gtgtggtcac cgatgatcag
     1261 ccggctgccc gaggcggccg tgacgggctt ctgcacctgg gcccagcggc cgatgacgca
     1321 gctctgcagg tcgcggacgt tcttgatggc ggcgccctcg aggatgatgg agtcctcgac
     1381 gccggagtcc tccaggacgc agtcgcgccc cacggccgtg tacgggccga cgctgctgcc
     1441 ggtgatgacg ctgccggcgc cgatcacgag cgggccggtg agcttggacc gcacgacgcg
     1501 ggcgcccggt ccgaggacga cgggcccctg cagaatgctt tccgcatcga cctcggcgcc
     1561 ctcgcggtcg gcggcggtgc cggcgatgcg ggcgaggatc tcccggttgc actccagcag
     1621 gtcgtcgatc ttgccggtgt ccttccagta gccctcgtac tcgcgggcgg tgaccgtccg
     1681 gcccgcgtcc accaggtgct ggatggcgtc cgtgatctcc agttcgccgc gggcgctggg
     1741 ctcgatggcg cgcaccgcct cgtgcacggc ggcggtgaag aagtacacgc cgatgacggc
     1801 gaggtcgctg cgcggcgcgc tcggcttctc cacgagggcg agcaccttgg agtccgcgtc
     1861 gacctcggcc acgccgtact ggcgcgggtc cgccaccttg gtgaccagga cctgggcgtc
     1921 ggggcggcgc tcgtggaagg cctcggcggc ctcggcgatg ccgtcggcca ggacgttgtc
     1981 ccccaggtac atcacgaagt cgtcgtcgcc gaggaagtcg gcggcgaggg cgacgcagtg
     2041 cgcgagtccg agcggggcct cctggcggat gtaggtgagg cgcagcccga gccgggagcc
     2101 gtctcccacc gtggcctcga tctgcgccgc gtggccgccg acgatgacgc ccacgtcctc
     2161 gatgccgatg tcccgcaggt tttccaggca gtgcaccagg acgggcttgt tggccacggg
     2221 gaccagttgt ttcgccatcg agtaggtgaa gggccgcagc cgcgtacctt cgccaccgga
     2281 caggaccagt gctttcatgg gttccccaga aattctcgca aggagacagg atcggggaca
     2341 acgtggtcga ccgcgctcga ctccgattcg agtcaccgtc gaactaatgt tgacaacttc
     2401 tctccccgtc gcggtcgctg aggacgagga gctgaggatc catgacggag cagacacggg
     2461 cgcaggcgga ggagcagcag gcgcaggccc tgtcgccgga cgaggtcggc gaggtctacg
     2521 acgagaaggg ctggctctgg gagatcttca tgggccagaa cctgcacatc ggctggtggg
     2581 acgacgaggc ccccggggtg gaccccaagg accggctcac ggacgtcctc atcgagcagg
     2641 tcgccctgcg gcccgggcag cacctcctcg acatcggctg cggccagggc cggccggcgc
     2701 tgcggctggc cgaggccagc ggcggtgagg tcaccggcat cacggtgagc gcggagcagg
     2761 tctcggccgg cacggaggct gcggccgggg cgggcctggc ggaccgggtg cggttcgcgc
     2821 tggcggacgt gtcggaactg ccctacgcgg acggcgagtt cgatgcggcc tgggcgatgg
     2881 agtcgctgat gtacctcggc gaccggcccg ccgcgctgcg cgagatcgcg cgggtgctca
     2941 agcccggcgg cgtgttcgtc ctgtccgact acgtcgagtc ggccgagctg gacgaggagt
     3001 ggcgcaaggt cctgctggag ggcttcacgg tgggctcgct gccgaccgcg gaccagtacg
     3061 tcgagatgat caccgcggcg gggctgaccg tcgagcggaa cttcgacgcg accgcgcacc
     3121 tgcggcgctc cgcggcgcgg atcgaccagc tcgtggcgga caactacgac aaggtcgtgg
     3181 agaagggcgg ggtgcagttc gccgaggagt tcaaggagat gatcgaccgg gtctcgaagc
     3241 tggagcggga catgctcggc tactcggtga tcaccgtccg caagccgctc gcctgagccg
     3301 cggggccctg ccgtcggccc gtcgagccgc cgtcgagcag ggttcgaggc ccgcttccaa
     3361 cgatgaccgc atgaagattc tctttgttgc gggaggcacc tccggggtga tcttcggcat
     3421 cgtcccgctg gcccaggccg cccgcaacgc cgggcacgag gtctttatgg ccgcccccga
     3481 gaacatgatg gcgaccatca cgggcgccgg gatccccggc gtcccggtct ccgacgtgcc
     3541 gatgatggac cacctcgtcg accggcgcgg catccgcgtg cccatccccg aggatcttca
     3601 cgagcgctac atcttcaacg ggcgcacgtt cggccgctac gccgccgcct gcctggacgg
     3661 cctgctgtcc ctggtggcgg actggcgccc ggacgtcgtc gtgggcgggg cgctcgcctt
     3721 cgccgcgccg ctgatcgccg ggcacctggg cgtgccgtac gtgaagcagg ccatcgacat
     3781 gggcgagccg cgcacgatcg acctcgcggc cgccgccgag ctgggcccgg agctggagcg
     3841 gctcggcatg tacgagatgc cgcgcacgga tctgttcatc gacatctgtc cgccgagcct
     3901 gcggccctcc gacgcgctgc ccgcgcagat gatgcgctac gtgcccttcg ccacccagat
     3961 gccggtcgag ccctggatgt acaccaaggg cgaccggccg cgggtgctgg tgtcggccgg
     4021 cagccgggtc accccggagt ccgacttcga catcctcagc ggcctcgtcg acaaggtcgg
     4081 caagctggac gtcgagctgc tcatcgccac gccggaggcg gtcgcggaga agctgcggcc
     4141 gctgccggac cacgtgcggg ccggctggat cccgctgcac ctggtggccc cgacctgcga
     4201 cctcgtcgtc caccacgcgg gcggcaacac gacgatgggc tacctctcgt acggcgtccc
     4261 ccaggtgctg gtgccctacc tgccctactg cgtcgactac tcgacccggc tgagcgccta
     4321 cggggccgcc acgatgatcg acccggccga cgacagcgcg gagaacatcg cgcgcgtctg
     4381 cgccgagatg ctggccaccc cctcctaccg cgagcgggcc gcggagctgg ccgccgaggt
     4441 gtccgcgctg cccacgtccg ccgacgcggt gcgggcgatc gagcggctcg ccgccgcggc
     4501 ctgacacccg tacgccagcc accgcacgcg tccgcgccac accgactccc aggggtacta
     4561 ccaaatgatc aatctctttc agccgcaggt cggggacgcg gaactcgccg ccgtggccga
     4621 ggtgttcgac agcaagtggc tcgggcacgg gccgcgcacg aaggccttcg aggcggcgtt
     4681 cgccgagcgc ctcggggtcg ccgcggagca cgtcctgttc gtcaactccg gtacggccgg
     4741 gctgttcctg gcgctggagg tcctcgacct ggccgagggc gacgaggtcg tcatcccgtc
     4801 catgagcttc ctcgcggccg ccaacgccat cgtctccacc ggcgcgacgc ccgtcttctg
     4861 cgacgtcgac ccgcggacga tgaaccccac ctgggagcac atcgaggccg cggtcacgcc
     4921 gcgcaccaag gcggtcgtgg tgctgcacta cggcggctgc ccgggtgacg tcgtggagat
     4981 cgcggagcgc tgccgggagc ggggcctggc cctggtcgag gactcggcct gctcggtgga
     5041 ctcccgcgtg gacgggcgcg ccgccggctc cttcggcgac ctggcgatgt ggagcttcga
     5101 cgccgcgaag gtgctggtca cgggcgacgg cgggatgctc tacgtacggg acgccgagcg
     5161 ggcgcagcgg gcccgccggc tcgcgtacca cgggctcgtg caggccacgg gcctcgccta
     5221 cgcgaaggtc tcgcaccgct ggtgggagct ggaggtcccc gaggtgggcc ggcgcgtcat
     5281 cggcaatgac ctgacggccg cgatcggcct ggtgcagctc gggcggctgc cggagttcac
     5341 cggccggcgc aaggagatcg tcgccctgta cgaccgcgaa ctcgcgggtg tcgagggcgt
     5401 gaagacgccg ccgccgctgc cggccgggca cgagtcctcg cactacttct actgggtgca
     5461 gatggacgcg cggatccgcg accaggtcgc ctccgacctg ctggccgccg acatctacac
     5521 gaccttccgc tacgcgccgc tgcacaaggt gcccacctac aagtccggcg ccgacctgcc
     5581 gggcaccgag caggcgtccg gcgagaccct gtgcctgccg atccacccgg ggctcgccga
     5641 cgcggacgtg ctcaccgtgg tggccgagct gcgcaaggcg atcgagacgc gcacccggga
     5701 cctggccccg gccgcgggct gaccggacgg gagacgggag accacgtcat gcgactgctg
     5761 ttcatgtccc cgctggccaa gaccctgcac gagacgacca tcgggctcga cctcgcggac
     5821 cagctcaagg acgccggcgt cgtcagtcac ttcgtgatcg acgagttcaa cgaggaccag
     5881 ctcaagaccg ctggatacgc ctacaccgtg atcacgcccg cgatgggcgg ccgggtccgc
     5941 gaggaggtcg cgcgcgtcgt cggggagttc cggccggacg cgatcgtcct cagcgactac
     6001 ctggcgcact ggctgaccca cctcgtcagc tacgagaccg acccctggta cgtcgaggac
     6061 ttcggcgtgc cggtgatccc catcgacctg cacgacctga cgaacatcac gcgggagctg
     6121 gaggtgctgg ggaggaccgt cgtcgccgac ggcaacatcc tggacatgcc ggtgcacctg
     6181 caccccgtgc cgatgggccg cccggaggcc cgggccggcg ggcagggcct gccgtaccgg
     6241 gccaaccggg gcatcgagcc gctgacggac gcggcgcgcg ccgaggtgcg ccggtcgctg
     6301 gggctcggcg gggcggagcg gctgctgatg ttcccgacgc tgccgtggca ggagacgatg
     6361 cagacgcggg ccggtccccg gacgcgcgag ctggcggtcc gcgtgccgcg gctgatcggg
     6421 cactacctgc gccggcttcc cgacgacacc cacttcgtcg tcgccgggcc ctacctggac
     6481 gggctggggc tgccgcccga gcgcgtccac gtggagccct cgtacaccgc gcagcgctac
     6541 cacgccctgg tcggcgcctc ggacgccgtg atgtcggcct tcctgccgtc ctacgcgctg
     6601 gagcgggccg tcctcgccga cgtgcccggg ctgttcgctc tcaacaccca cgacatgggg
     6661 gaggcggcgg gcgacggcgg gcgggccggg gcgccggacg ggctctcgcc cgtggtccgg
     6721 gagtggctcg cggacttccc cggcgccgtc cccgccttcc acatgtggcc cctgagctgg
     6781 aacaaggtca tggggccgct gctggtggac aacccgttcg ccgacaccgc cgtacgcacc
     6841 gagctgttcg acgagcgggc cgtcgtcgag ggcctgacgg gcatcctcca cgacccgctg
     6901 gtccgcggcc gtcttgcgga ggcgcgcgcg gcctaccggg acgggatcga ccggctcccg
     6961 gagaccgccg aggtcttcgc caccgcggcg cggcgcgtgg gcctgacgct ctgacgcgca
     7021 gggcccctcg gcgctgagcc tccttcgagc ggcgctctaa ccgggtgccg aatgctgaag
     7081 caaccgcaca tcatgaggag ggctgccgtg ttccggcaga caagcgaatt ccacgactgg
     7141 ttcgccgaac agcgcgcggc gcaggaccac cgggtgacgc ccgccccgct gcgcggcctc
     7201 gacggctggt cgttcgagcc ggggaccggc gacatccggc accgcagcgg gcggttcttc
     7261 agcatcgagg gcatcgcggc ggagaccgac aaccgcgagg tcgccgcctg gtcgcagccg
     7321 atcatcgtgc agccggagtc cgggatcctg ggcatcctgg tgaaggagtt cgccggcgtc
     7381 ccgcacttcc tgctccaggt gaagatggag ccggggaaca tcaacatcct gcagctctcc
     7441 ccgaccgtgc aggcgacgcg gagcaacttc acccgggtgc accaggggaa cgccgtcccg
     7501 tacctggagc acttcctggc gccgcgctcc gggagggtga tcttcgatgc cctgcagtcg
     7561 gagcaggggt cgtggttcct gggcaagcgc aaccgcaaca tgatcatcga ggcggacggg
     7621 gacgtccccg tccgcgacgg cttctgctgg ctcacgctgg accagatcgg cgagctgctg
     7681 aacgtcgaga acctcgtcaa catggacacc cgcaccgtgc tgtcgggcct gcccgacggc
     7741 tgggccgtcc agggccgcag caccggcgcc gagggccggg ccctgcacgg gacggccgcg
     7801 ctgctgagct ggttcaccga ggccaaggcc tcgcaccggc tcgaccgccg ccgcatcccg
     7861 ctggcggagg tcgggggctg gggcgagtcc gacggggccg tggtgcacga tagcggccgc
     7921 ttcttcaagg tcatcggcgt ggacgtcgag gcccagggcc gcgaggtcgc ccgctggtcg
     7981 cagcccatga tcgcgccggt cgggcggggc gtgatcgcct tcctcacccg gcggatcgag
     8041 ggcaccgtcc acctgctggt gaacgcgcgc accgaggcgg gcagcttcga cgtcctcgaa
     8101 atgggcccca ccgtgcagtg cgcgcccgcc aactacgagg ggctgcccgc cgggagccgt
     8161 ccgcggttcc tggacgaggt cctctcggcc gcccccgagc gggtcctgct ggacgtcgtc
     8221 cactccgagg agggcggccg cttctaccac gcggagaacc gctacctcgc ggtcgaggcg
     8281 cccgacggct tcccgctcga agtcggcccg gaccacatat ggatgacgcc tcatcagctc
     8341 ggggcgatgg tccgccactc ccaccacgtg aacgtcgagg cccgcaacct cctggcctgc
     8401 ctgcggttcc tgcggtgacc gccgccgagc gggaccccgc gacccggacc gtgcgcctcg
     8461 gcctgatggg ctgcgccgac atcgccctgc gccggatgct gcccgccgtg gcgcggaccg
     8521 ggggcatcgc gctcacggcc gtggccgccc gcgacaccgc ccgggccgcg caggtcgcgc
     8581 agcagtacgg ggccgaagcc gccgccggct acgcggagct gctggagcgg gacgacgtcg
     8641 acgccgtcta cgtgccgctg ccctcggcgc tgcacgccga gtggaccgag cgcgcgctgc
     8701 tcgccgggaa gcacgtcctg gccgagaagc cgctgacgcc ggacgccgcg gagacggcac
     8761 ggctggtgga cctggcccgc tcccgcgggc tggtgctgat ggagaacttc atgttcgtcc
     8821 accacccgca gcaccggcgt gtgcggcagc tgctggacga gggcgcgatc ggcgacgtcc
     8881 gcaccgtcca cgccgcgttc gccgtcccgc cccgtcccga cggcgacatc cgctaccggg
     8941 ccgacctggg cggcggcgcg ctcttcgacg tcggcgtcta cccgctgcgg gccgcccagc
     9001 tgctgctcgg gcccggcctg gaggtggtcg gcgcggacct gcgcaccgac ccggagcggg
     9061 gcgtggacgt cgcgggcagc gtgctgctgc ggcggcacga cggggtgacc gcccacctca
     9121 cgttcggcat ggaacaccac tacacgtcac gttacgaagt gctcggcagc gcgggccggc
     9181 tccgcctcga ccacgccttc acgcccccgg ccgaccaccg cccggtggtc gtcgtcgagc
     9241 ggcacggcgg cgtcgaggag ctggagctgg agccgttcga ccaggtcacg gccgccgtcc
     9301 gagcgttggt gacaagcatc ggatccggcg ccggtacgac gaccggcgag gcgaccgtcc
     9361 gccacgcgga gctggtcgcc gacgtccacc gggcagggca cgcgcgcaga ggccgggccg
     9421 gcaccgcccg acgactcgct gagtacgccg taggaggcga agagaaatga acgaggccaa
     9481 ggcccgcatt ctggagcagg tccgtgagta ccacggcagc gacgagaagg agttcgtccc
     9541 cggggagacc ggcgtgtggc cggccggtgc cgtcttcgac gccgacgacc gggtggcgct
     9601 ggtcgaggcc gcgctggaca tgcgcatcgc cgccggcgtg agctcccgcc gcttcgagcg
     9661 ccagttcgcc aagtacttca agctgcgcaa ggcccacctg accaactcgg gttcctcggc
     9721 caacctgctg gcgctgtccg ccttcacctc cccgcagctg gaggaccggc ggctgcagcc
     9781 cggcgacgag gtgatcaccg tggcggcggg cttcccgacc accgtcaacc cgatcatcca
     9841 gaacggcctg gtgcccgtct tcatcgacgt cgagctcggc acgtacaaca cgacgccgga
     9901 gcgcatcgcc gaggccatcg gcccgcgcac caaggcgatc atgatcgcgc actcactggg
     9961 caaccctttc gccgtcgagg aggtcgcgaa gctcgccgag gagcacgacc tcttcctcat
    10021 cgaggacaac tgcgacgccg tcggctcgct ctaccgcggc aagcccaccg gcaccttcgg
    10081 cgacatcgcc accaccagct tctaccccgc gcaccacctc gcgatgggcg agggcggctg
    10141 cgtgctgacc gacaacctcg cgctcgcgcg catcgtcgag tcgatgcgcg actggggccg
    10201 ggactgctgg tgcgagccgg gcgaggacaa ccgctgcttc aagcggttcg actaccagat
    10261 gggcgacctg ccgcacggct acgaccacaa gtacatcttc tcccacgtgg gttacaacct
    10321 gaaggcgacc gacctccagg ccgccctcgg cctcagccag ctctccaaga tcgacgcgtt
    10381 cggcgcggcc cggcgcgcca actggaagcg gctgcgcgag ggcctggacg gggtgccggg
    10441 gctgctcctg ccggaggcca cgcccgacag cgaccccagc tggttcggct tcgccatcac
    10501 cgtgcggccc gaggcccgct acacccgcaa ggacctggtg gcgttcctgg aggcccggaa
    10561 gatcggcacc cgccgcttct tcgccggcaa cctcacccgc caccccgcct acctggaccg
    10621 cccgcgccgg atcagcggct cgctcgccaa cagcgacctc gtcgccgagc acaccttctg
    10681 gatcggcgtc taccccggtc tcacccccga gatgatcgac tactcggccg agtccatccg
    10741 ggacttcgcc gcgaagaact cctgacgccc gcacctcctg aagcccgcac ctcctgacgc
    10801 gcgccggccc ctcccggcgc gcccgcaccg ctacccaccg caccaccgca caccacagga
    10861 gccctcacga tgaccaggga agcagccgca gccgcaccca ccctgctgga ggccgccgtc
    10921 gcggccgccc cgctcgccgc cgcgcacgcc gcggacgcgg aggcggaccg ccgcctctcc
    10981 ccgcccgtcg tggaggcgat cgtggcggcc gggttctccg gacacttcgc cccggcggcg
    11041 ctcggcggtg cggccgggac cttcgcggag ctcctcgacg cctccgccgc gctcggtgag
    11101 ggctgtgcct cggcggcctg gttcgcctcc gtgatcgcca gcgccggacg gctcaccgcc
    11161 tacctgccgc gggaaggccg cgagggcgtc tgggccaagg ggccgcagac cgtcgtcgtc
    11221 gccgggctca tgccctccgg caccgccgag cgcgcccccg gcggcggctg gcgcgtcacc
    11281 ggctcgtgga actacgtcag cgccgtcgac ttctccgact ggacgctcat cgccgcccgc
    11341 accggcgagc agggcaccgg cgtgcgggtc ctcgccgtgc cccgcaccga ctacgcgatc
    11401 agcgagacgt ggcaggtcat cggcatgcgc ggcaccggca gcaacaccgt cgtgctcgac
    11461 gaggtgctgg tgcccgacgc gttcaccgtc cccctcgacg tgctgctcgc cggcctcgcc
    11521 cccgaggcgg aggcggcctg ccaccgggtg ccgatgaagg ccgccaacgg cgtcaccctc
    11581 gccgggcccc tgctcggcgc gacccggggc gcgctgcgcc gctggcgcga gctcgtcgcc
    11641 gccaagcttg cggcccccgc gggcgccatc tccggcggct ccgaccacgg caccttcgaa
    11701 cagctcctgg cccgcgccga gggcgagatc gacgcggccg ggctgctgct ggagcgcgtc
    11761 gcccgcacca ccgactccgg tgccgtcgac gggctcggca ccgcccgcaa cgggcgggac
    11821 tgcgcgctcg ccgcggagat gctcgcgacg gtctccgacc gcctgctgcg ctcggccggc
    11881 acccgtgccc aggccgaggg cgaggagctc cagcggcgct ggcgggacgt gaactgcggt
    11941 gcgggccaca gcggtctgca gttcccggcg gcggcgggcg cgtacgcccg gctgctgaac
    12001 gcctctgcct gaacgcctct gcctgaacgc ctctccgcct gaacgatccc cccctgaccg
    12061 gctggccggt cactccacgg gaaagcgccg gacgggcccc tttacgggtc cgtccggcgc
    12121 ttcgtgcgcg ggtgaccgcg gttcagaggc cggcgggcac caggcggcgg cgctgcgcgg
    12181 gcaccgtctc cgacgggttg aggacgtcca gctgcagccg ctgcagctcc ggggagggct
    12241 ccaggcccag ctcgtcgttg aggatccggc gcaggctctg gtacgcctgc agggcctcgg
    12301 cgcgccgccc ggagtggttg agggcggaga tcagctggcc gtggaaccac tcgttgagcg
    12361 ggtagtcgtt gaccagggcg cgcagcaggg ggatggactc gcgctgccgg ccgagctgga
    12421 gctccgcctc gatgcgcagc tccagggccc ggatgcgcag ctcgttgagg tgcacgatgc
    12481 ggccggtcag gacgtcgccc gcggggatgt tggagagcgc ggggccccgc cagagggcca
    12541 gggcctgctc caggcgctgg acggcggcct cgggccggcc gttctccagc gccgtcttcc
    12601 cctgcagcac gaggcgttcg aagatcttga tgtcgacctc gtggtcctcc acgcggatga
    12661 ggtagccggg cggctgggtg atcagcaggg cccgctcggc gggcaccagc cgctcggcta
    12721 tgaacatctt gcgcgcgtgg tagatgtacg tctgcaacgt ggtcagggcg ctgcgcggcg
    12781 gggactcgcc ccagagctcc tggatcagcg actccgaggt gacgatctcg ttgggccggg
    12841 tcaggagcag ggccagggtc tgacacacct tcggcgtgct gggcaggtgt ggtggtcgtc
    12901 cgtctccggt gacgatctcg aacgggccga tgaggttgaa tcgcactgca cacactcctg
    12961 taccgggtgc aaaagatcct gtgccacgtt gagcaagtgc tgacaacgta ggtgtcggcc
    13021 gcacaaaacc cccacctcgg tttgatgaga gtgtcaggct accgaccggt aggttttctt
    13081 tcttgcgagg cccgtcacgt gcgcttcata cgcgtgtcat gcgtggcacg ccggcagccc
    13141 gccgtggtac tcgatcatct ccgagaagag caggccgatg tccagcggac ggccgggagg
    13201 cgcccccttc tcctccgcgt aggcgcggtg cagattgggc accaggcgct cggagtcgag
    13261 cagttcggcg tactccccga ggtccgcctc gcgcgcggcc tccagcgggc cgatccccgc
    13321 cgccaggccg gcccgcgcga tctcctggac gcgccgcagg tagccctccg tggtgtccag
    13381 caactccggt ccgcccacgg ggccgtggcc cgcgacgacc gtcaccgggt cgagcgcgcg
    13441 cagctgctcg gtgacggcca gcgagccgga gaccgagccc atcaggcaga acggcgtggc
    13501 ccccgacatc accaggtcgc cggtgaacag gacccgctgc tcgggcagcc agacgaccgt
    13561 gtcgttggtg gtgtgcccga tgcccgggtg cagcagctcg gccgtgacgt ccccgatgtg
    13621 cagggtcagc cggtcgcgga aggtgagggt gggcagctcg acggagacgt cgccccagca
    13681 cacctcgggc cacaggcccg tcaggtgcag gccgatgtcc gccatctcgg tgcgggtgcg
    13741 ctcgtgggag acgaccaccg cgtcgtcggc gaacaggtag ttgccgaagg tgtggtcgcc
    13801 gtgggagtgg gtgttgacga cgaactgcgg gggccgcgcc gtgagcggcg cgacggcctc
    13861 cttgagggcg cgcgcccgcg cctccgtggc ggccgtgtcg accagggcgg agcggttgcc
    13921 gccgacgatg aggccggcgt tgttcaggca ccagccgccg tcgggctgga tgtaggcgtg
    13981 gacgttctcc gcgacctctt ggaggcgggg ggtgtcgtgg gtgttccggg tgttcacggg
    14041 gtgcgctccg tgggtgatcg ggggtggacc cgatcactgt ggcgagcggg gatcgagcgc
    14101 gggtcgaggg ggacgggccg ccagcaccgc cgccgccagc cccgcgtcca ggaccgttcc
    14161 cgccgtcggt cgtctcgccg tgccgaagac cgccggggcc accgccgcgc tgaccgtgta
    14221 gcccgcgtcc agcgtgtggg actccaggtg ccagtcgccg tcgtcggccg gtgagccgtc
    14281 cgagcgcagc aggcgggccg tggcgcccga cgcggcgggg atcgtgaagc cgaaggaggt
    14341 gaagggcagc cgcaggccca ggcccagggc cttgctgtac gcctccttga gcgtccacag
    14401 gcggatcatg gacgcgttgc ggtcctgctc cggcagccag cccagcgcgg cccgctcgta
    14461 ggcggtgaag gactcctcgg ccagccccgt gccgtagatg gagcgcgccg aggactccac
    14521 gtcgaccccg atcgggccga cgtggctgag gcccaccgcg aggatgtccc ccgtgtggct
    14581 caggctcacc tccagctgcc cgcaaccgcg caggtagggc ctgccgttgg ggttgcgggc
    14641 cagttccagt tcgcccgggt cggcgtccag gacggcgccc gccgcgtact tcagcaggag
    14701 ccgggaggcg gcgaagcgcc gccgggtccg ttcctggcgg atgcctgcgt ggcgcccggc
    14761 ctcctgcccg agcagcctgc cgagttcgtc gtccggcagg ccgtgctcgc cccagtcggc
    14821 catcagcccg tagaggagcg cgaagccccg ctcgtccatg gcggtgtccg tggcggtcca
    14881 cgggccgtcc ggggccgtca cccggacggg cgccgaaccg gccagccccc ggggaccgga
    14941 tgtggccatg tcatctccct ttatgtggta gccggttatg cggccgacgc tgtgcggcgg
    15001 gtgctacgcg gcggccggcc cgccgcccag cagcacgtcg tacaggtcga ggctgcggcc
    15061 ctgtgtgcag cgctccacca ccgccgcgag cagcgcctcg ccgcgccggt cgtcggcggc
    15121 gggctcgggc aggccgaggc ggaactggac cctgccgagc gcggcgatca gccaggcggg
    15181 gtcggacagg aagcccgcct cccgctcccg gtcgccgtgc agccacacgc ccaggcaggc
    15241 ggccgccgcc gcgagcaggg tgtagcgctc ggcgagggcg tagccgtgcg gggtggccag
    15301 ggcggcgagg tcctgctcgg gcagcgcgcg gcactcctcg ccgagcgccc gcagctccgc
    15361 ggccagcgcc cgcacctgag agcgcagcgc ctccccgtcc gggccggtga cggggagggt
    15421 gtccagggcc gcctcggcgt gcggcagcac cgccatcagg gtgtccccgc cggcggcgag
    15481 gtcgagccgt ccggggtcga gcgggggcag gggcgccgag gtggagaaga ggccgggcgg
    15541 gggcgtggcc gcggtccacg aggtccgggc caggaagggg agttggggga ccagagtggc
    15601 cagcgcggcg gcggcgccga tcggccccgg cgggatctcg gacaggtcgc gcaggtgttt
    15661 gcggaacgtg ccgaagccgc cgtcctcctg cagggcgcgc ggccccagga cggccgcgag
    15721 gtcgcccgtg ctctgctgca gcatgcgcac caccaggcac atggcggcgg ccgtccagac
    15781 gctggactcc tcaggcagga ggtgcagcga gcggatcgcg gccagcagca ggcagtcgca
    15841 caccagcatg tccgcgaacg aggacgtgat cgcgcgccgc gcgtaccgcg aggtcagcgg
    15901 gcgcaccccg ggcgcgcgct ccagcaccgc cgcgaccacc gagcgcagtg cggtgtcggc
    15961 gcagccgacc gccatcgacg gcacgagcgg cctgctgacc tgcagggacc gcagggcgac
    16021 cgccgtgccg tcgccgggcg cgccgagcac gctgcccgcc ggcacgggcc agcggacgaa
    16081 ctccaggaag cccgcgggca gccggcgcac cgcggtggcg tcgtacgggg acagcagccg
    16141 cacggcgtcc ggcggcaggt cggcgcggtc caggagcagc gccgagtggg cgccgtcgcc
    16201 gtccgcgtgc cgggccagca ggacgaagcc cgcggccagg ggcgcgttgg cgatcagcgg
    16261 ggtgcggccg tccagcaccc cgccgccctg cggcgcgggg gtcagggtga ggtcgccgct
    16321 gctgaactcg ttgccgtagg acatgttctg gaacgcgacg gacagccgcc cgccgtccag
    16381 gagcagccgg gccgtgcggg cctgctgctc cggggtgccg tggcaccagg cgaacaccgc
    16441 ggagaccagg gaggccgaac cgtggccgcg gccgagggcg aagtcccgcc ggaacaccgc
    16501 gcgcagcagc tgcgtcgcgg tgtccaggcc ggtcagccgg ccgccgaggc gctgcgggac
    16561 gatctcctcg cgcaggccga aggcgtccag caggggctcg ccgcccagcg gcagctcgcc
    16621 ccggcggtcg gcggccagcg ccgcggcgtg accgagcggg ttgcccgggt cgagggggtc
    16681 gccgagccgg cgctccagtg cggccacgcg gtcggcggag gggacggcgg aggggacggc
    16741 ctcgctcagg gagccgatgt cagaagacct ggtcatgggt gatcaggcgg gacttcagct
    16801 gcacctcgcc gccgttcacc accagcgtgt cgtgcacggt gcagctcggg ttgatctcgg
    16861 gcttgccgcc ggggcggacg gtcaccacga gggcgtacac cgtcgacttg accgtgccgt
    16921 cgtcctgcgg gtccagggcg atctggttga accagtggcg gcgcgtgacc gggtccccgt
    16981 cgaacttctt gtggaagttc accagctcct cgacgatgcc ggggcggccg acggcgggct
    17041 cggcgcccgg cgagtgctgg aagacgccgt cctcggtgaa cgtcgccgcg tactcctcga
    17101 agcggcgggc gtccaggtgg tgcatctggt gggcgtagaa gtgctggacc tgggagtgga
    17161 gctccgtcag ggactgggtg gcggtcatgg tgcctctccg ggaacgaagg aagaaggggg
    17221 agggaaaggg ggggaggggg gaaggaggag agagaaaggg gtcagccggc ctgggcggcg
    17281 gcgcgctgct cggcgtaggt cgcggcgtgc gccatggtgg cgaggctgtt gcggccgagg
    17341 gcctcgcgca ggtacgcgcg ggcgtcggcg agcgtggcgc ccgcgcccag gacctcggtg
    17401 accgcctcgg ggttgaccgc caccgtgtgc cgggcggtgg cgacggcccc gcccccgggc
    17461 ttgtccgcga agtgccacag gccgctgtgg ccgagcagca gcttcggcat gacgtgctgc
    17521 ttgtaggcga tccactccgg gccgcggcag atgcgggtgg agcgcgtggt gtgggccgag
    17581 ccgtcggcgg tgacggtgtc catctccagg tcctggatgc cggggacgtc ctcggtcagc
    17641 cgggcctgcc ggacgtgcgg gagccgctcc gcccacaggt cggcgcggtc gacgaagtcg
    17701 aaggcgtcgg cggccgaccc cgtcagctcc acggtgtcgg tgaaggagaa caccacgtcg
    17761 gacgcggtgc cgccgtactc ggcgatccgc gccagcgccg ccagctcctc ggggctgttg
    17821 cggtcgagcg cggcgttgac ggccgcgacc gtctccgggg cgtcgccgac ggccgtgaag
    17881 tcgtggagca gcaccacgcg ggtgccgccg cccggcagcg cctcgaagat ccactcgccg
    17941 cccatggagg cgacgggggc cgtgctgcgc tcctggcgga aggtcacgcg cagcgcctcg
    18001 gggtcgaggg tgcgccggga ggtccaggtg ctgaccttgc cgttgaccgt ggcccagatc
    18061 tcgaagcgct ccgcccgctc gccgcgctcc aggtggtgga cgtggacgct cggcccgaag
    18121 atcgcgggcc aggtcgtgac gtccgcgacc aggccgtaga gcacctccgg gggcgcggaa
    18181 acatccaggg tgtgctcggt gtggtgccgg cgcggttccg tcatgtcgtt cgtctcctcg
    18241 gtgcgtacgg ggccgggccc gggcacgtgg gtgtcccgtg cccggacccg ggtgctgcgg
    18301 accgcccggt gcggcgcgcg gcgcgtcagg cggcggcggc ctcggtgacc aggccgttga
    18361 cgaggtcgat gagcgcgcgc ggcgtctcga cctcgacgag ctcgtcgtcc gggacgacga
    18421 cgccgaactc ctgcttgatc tgggcggcgc tctccatcag ggcgagcgag tcgtagccca
    18481 gctcgtcgaa ggggcggtcg gagatgtcgc cggtgatgtc gatgctgtcg tcgacgccgg
    18541 cgcactcgac gaggatgcgg cggacgtcgt caacggtcat gtgggccatg ggttctgctc
    18601 caagcggtag agaaggccga tggggtgagg ggagccggcg cccgtgccta cgcggcgcgg
    18661 acgacgacgg ccgagttgaa gccgtgccgg ccgcgggcga gcaccagggc ggtgcggacc
    18721 cgctggtcgc ggggcgcgcc ccggaccagg tcgaggccgt aggcctcggg caccggggcg
    18781 cccgtggggg tcggcgggat gacgccgtcg cggatcgaca gcagcgccgt cgcgacgtcc
    18841 agcgggccgc cgccggagta gagccggccg gtgagggcct tcggggcggt gacgggcacc
    18901 gctccggcgc cgaagacgcc gctgatggcg gcggcctccg ccgcgtccag cccgggcacg
    18961 ccggcaccgt cggcgaagac cacgtcgatg tcgccgggcg cgaggcccgc gtcggccagg
    19021 gcggcctccg cggcgcggcg cagggccggg gggcggccgg tgccgggggc ggggtcgaag
    19081 gtggcggcgt agcccgcgag ttcgccgtag acctgctgcg cgccgcgctc gcgggcgctc
    19141 gcctcgtcct cggcgacgag gatcgcgccg ccctcgccgg gcacgtagcc cgaggcgtcg
    19201 gcgctgaagg gcaggtaggc gcgggcgggg tcggtggcgg tggtgacgcg gccgccggcc
    19261 agctgggaga cgtagcccca cgggtcgagg gcggagtcga cgccgccggc caccacgagc
    19321 ggggtgccgc ggcggaccgt gcggcgggcg tggccgagcg cgtccaggcc gccggcctgc
    19381 tcgccgacga gggcggcgct cggtccgcgc agcttgtggc ggatggagat ctggccggtg
    19441 ttgaccgcgt agaaccacgc gaaggactcg tagacgctga cgaagtccgg gcccttgttc
    19501 cacagcttgt cgaactcgcg gtgggtgaag tcgaagccgc ccatggcgtt ggaggtgacg
    19561 acgcccatgt cgtagtccgg cagggtgtcg ggggagacgc cggcgtcggt gagggcccag
    19621 tcggcggcga cgagcgcgag ccgcgtcgag gggtcggtct gcgggagcag ccggctgttg
    19681 aggtgctcgg ccgcgtcgaa gtcgtcgatc tggccggcga gggaggacgc gtagcgggag
    19741 gcgtcgaagc gggtgacggg gccgatgccg gtgtggcccg cgagcaccgc cttccagaag
    19801 gcctcggtgc cgaggccgtt gggggcggtg acgccgatac cggtgatgac ggtccgcccg
    19861 ttgaggccgt ccttgctggt catgccttca ctccttccgg ggcgcgcagg atcatcgcgc
    19921 tctggaaacc gccgaagccg ctgccgacgg tcaggacgga gtccacccgc tgctcgcgcg
    19981 cggtcagcgg gacgtagtcg aggtcgcact cggggtcggg cgtgtgcagg ttggccgtcg
    20041 gcggtacgac gttgtgcttg atggccaggg cgcaggccgc gatctcgatg gagccgatgg
    20101 cgcccaggga gtggccgacc atcgacttga tggagctgac cggcacgtcg taggcgtgct
    20161 gtccgagcgc gatcttgaac gcggccgtct cgtggcggtc gttctgcttg gtgccggagc
    20221 cgtgcgcgtt gacgtagtcg acgacggtcg ggtcgacgcg ggactcgtcg agcgcggcgc
    20281 ggatggcctc cgccatctcc cggccgtcct tcttcagacc ggtcatgtgg tacgcgttgc
    20341 agcgggtggc gtagccggtg acctcggcgt agatctgcgc gccgcgggcc ttggcggcct
    20401 cgtactcctc caggacgaac atggcgctgc cctcggcgag gacgaagccg ttgcgggagg
    20461 cgtcgaacgg ccgggaggcg tgctcggggt cgtcgttgcg cgtggtggtg gccttgatcg
    20521 cgtcgaagca ggccagcacg atcggggaga tcggggtgtc cgacgcgccg gcgatcatca
    20581 cgtcggcgga gccctcgcgg atcagctgga cgccgtagcc cacggcgtcg aggccggagg
    20641 tgcagccgtc ggagaccatg gtcacggggc cctcggcgcc ggcggcccag gcgacctcgg
    20701 cgggcatgac gcccgggctg aggtagtcga acatgtgcgg cgacaggtag tcggggtcga
    20761 ccagccactc gcggcccttg tcggccatca cgaggtactc gttctccagg ctggtcgcgg
    20821 aggcgacggc gctgccgagg ctcacgccca cgcggtgcgg gtccacgccg gcgaactcca
    20881 ggccgctgtc ggccacggcc tcccgggtgc aggcgacggc gaactgggtc gcccggtcca
    20941 tcctgcggat ctcccggggg gagaagccct cggcctcggg gaagaagtcg gcctcggccg
    21001 ccacctggga ccggaacgga gccgcgtcga agaacgagat ccgccgggtg gcggtgcggc
    21061 ccgcggtgag caggtcccag aactccttgg tgccggagcc gcccggggcg cggacgccga
    21121 taccggtgat caccactcgt cgggtcatcg cgtgggcacg ccttccttcg agctgaacat
    21181 cgagtcacgt tcctttccgc ttgccgtgca gcagatgtcc accgctgcct gtcggggaca
    21241 gcgccgttgg caagggaaac ggtgcggctc gggcctcgaa caccgctcga agacggatgg
    21301 ggtacctcca caagaaaccg gctggccggt ttctcttggt aatccgacgt cagagagccc
    21361 gtaggcaggg cttccggtcg gtttcccatg aggtctgcgg cggcgtagag agggaggaaa
    21421 gtggacaaat gtggtcaggg tgaatcgtta ggtcaaggtt tcaaagagta atagaaacaa
    21481 cgcagtcggt ttggtacggt caaatgcgcc gtcggtagcc atcacgtggg gagagacgat
    21541 ggaagccaga tccgtgcaac tcagccctgt gtcctccgag gaaccaccct tcgggcaccc
    21601 gtcccccgcc gacccctggg acgtggaacc ggagttcttc tcgtcactca cgcgcaacga
    21661 ccagcgcagg atggcggagc agtacgtgcg cggcctgctg gaggcggagg gccgcaagac
    21721 cctgcgcaac gtcgcggaac agatcggcgg gaaggcgctc cagcagagcg tccaccactt
    21781 catcaccgcc tcgtcctgga actgggcccc ggtccggcgg gcgctcgcgc gccgcgcgga
    21841 ggaggaggtg cgcccccagg cgtgggtggt caactccacc gtcattccca aggcgggggt
    21901 gcactcggtc ggcgtcgacc agcagttcct cccccacctg ggccagacgg tcaacggcca
    21961 gcgggccttc agcgtctgga gcgcctccga gcgggtcagc gtgcccttca actggagtct
    22021 ggtgctgtcc aggagctggc tggaggaccc ggcccggcgc agccgcgccc acatacccga
    22081 cgccagccgc gccatctccc tggaggagca cgccggagcc gtggccctgg aggccgccga
    22141 ctcctggggg ctgcgcaggc gccccgtcgt cgtggacgtg gaggggctcg acgcgggggc
    22201 gaccgtgcgg cgcttcgcgc gcgcgggcgt gccactgatc atgcgcatcg acggcacgac
    22261 cccgctgcgc gtcgacggcg ccctgctgca gggctacagc gaccgggagg tgcccgcgca
    22321 gaacctgatc ggctcgatga agcggatgcg ccggcaggtc gagtggtccg acacctcggg
    22381 gacgggctcg taccgcgggg tggtgagcgc gatcccggtg gtcctgtcgt gccccgcccc
    22441 cgcgggcgtg cccgggggca cccaccaccg gcccatgctg ctgatgggcg actggggctc
    22501 ctccgaccgg tggccgtcgc ggatgtggct caccgactcg cggcggctgc cgctggtcac
    22561 cctgctgcgc ctgacccggc tcacgggcgt cgtccagcgc gacttcgcgg agatatccga
    22621 gcacaccggc atccgggact tcgcgggccg ctcgttccgc ggctggcacc gccacgtcac
    22681 cctggcctcg gtcgcccacc tcatcgccgt gcgggcgggg gcgcgccgcg tcccggcgca
    22741 gcggcggcgg gcggcggggt ccgccgcgcc gctgtgcgcc tgagcggagt ccgccccggc
    22801 gggtcagtcc gccgcgccgg ggccggcgat cccgtggaag cccttccggt agtacaggag
    22861 gggctccccc tcgccggcct cggcgtgctc cacctcgccg aacagcacga ggtggtcacc
    22921 ggccggcacc tgccgctcgg tgcggcactc cagccgggcg agcgcgcccg gcagcagggg
    22981 cagcccgcgc cgggagctgg tcatccccgg ccgggggaac ttgtcggcgc cccggcgcgc
    23041 gaagagcgcg gccaggtcct gctggtcccg gccgagcacg tggacgacga acccctcggc
    23101 gccggtgaag gcgtcgaagc agttggcccg caggtccagg cacacgagca ccaggggcgg
    23161 ttcgagggac acggaggtga aggagctggc agtgaaaccg tggctgcggc cctgtgcgtc
    23221 cacggtggtc acgaccgtga cgccgctggc ccagcgggcg agggacgtcc ggaaccgttc
    23281 ggcggtgatc gtctctgcga gcatcccccc acgctgctca gcgccgcttg agccgggatc
    23341 gagccgtggc ggaaccgccg cggcggaacc cgcgcttcgc ccccctcgga acccgcgctt
    23401 cggcccctcg gaacccgcgc ttcgaccccc tttcgaccgg ccgtcgaggc cgcggcggca
    23461 ccctcggcgc gaccggcgtc tcggcgccgt cagtattcgc aaccagctac ggaggaacga
    23521 tgggcacgca gcacgccaag gtcgcactgg tgaccggggc aaccagtggc atcggtctgg
    23581 cgatcgccac ccacctggcc cgcaacggcg cccgcgtcta cctgtgcgcc cgggacgcgg
    23641 cgaagctggc ggagaccgtc aagtccctgc aggaccaggg cttcgaggcc gacggcacca
    23701 cctgtgacgt gaccgaccgc gaggacgtca agcgcttcgt ggccgccgcg gtggagcgct
    23761 tcggcaccgt cgacatcctc gtcaacaacg ccggccgcaa cggcggcggc gcgatcgccg
    23821 agatgtccga cgagctctgg tacgacgtga tcaacaccaa cctcaacagc gtcttcctcg
    23881 tgacgcgcga ggtgctgagc gccggcggcc tgctcaccaa gggctggggc cggatcgtca
    23941 acatcgcctc gacggccggc aagcagggcg ccgtcaccgc cgccccgtac tccgcctcca
    24001 agcacggcgt ggtcggcttc accaaggccc tcggcctcga cctcgcgaag accggcatca
    24061 ccgtcaacgc cgtctgcccc ggcttcgtcg agacgccgat ggccgagcgc gtccgcggcc
    24121 actacgcgga gatgtacggg atcaccctgg aggaggcggc cgagaaggtc accacccgcg
    24181 tcccgatcgg ccgttacgtc gacgtcgagg aggtcgcggc catggtcgac tacctggtcg
    24241 gcgacggcgc ctcgtccgtg accgcgcagg ccctcaacgt ctgcggcggc ctgggcaact
    24301 actagaggtc cccgcggtgc cggaccgggc gcggaacaca cgtgtccggt tcgaccgccg
    24361 ctcgaattcc gcacgagccc gtcgcggcag cctgtgcagg caccacccac aggcaggcag
    24421 gacgacagga gcaagcggtg acggattcac ccgtagggac acgcatacgc acggcggccg
    24481 tgatcggcgt gggcaccatc ggcctcggct gggccgcgct gttcgcctcc gccgggctga
    24541 ccgtccggat caacagccgc cggccggacg ccgaggcgca cgtccggaag gcgttcgagc
    24601 tgtacgcggc ctcgctgccg ggcggccccg ccgacccggc cgggctcgcc gcccggctgg
    24661 agttcgagcc cgacgtggcc cgcgccgtcg agggcgccga cgtcgtccag gagaacgccc
    24721 ccgaggacct ggccctcaag caggacctct tcgcccggat cggcgccgcc gcccccgccc
    24781 atgcgctgct gctgtcgtcc acctccacgc tgctccccga cgccctgggg gcgcggatgg
    24841 ccgaccccgg caggctgctg gtcgcccacc ccttcaaccc gccgcacatc gtgccgctgg
    24901 tcgagatcgt cacgggcgag cggaccgacc cgcgggccgt cgaggagacc gtggccttct
    24961 accgcggcct cggcaagacc cccgtcgtgc tgcgccgggc cgtccccggc ttcgtcgcca
    25021 accggctgca gtccgcgctg ctgcgcgaga gcatccacct ggtccgcgag ggcgtcgtct
    25081 ccgtcgccga gctggacgag atcgtcacct cctcgatcgg cggccgctgg gccgcggtcg
    25141 gcccgttccg cgccttccac ctcggcggcg gccccggggg cctgcgccac tggttcgagc
    25201 acctcggcgc cggcctggag aagagctggc aggggctcgg caacccgccg gtcgacgagg
    25261 agaccgtcgc ccggatcctc gcccaggcgg aggaggcgtt cggcggccgc acctacgagg
    25321 agctcgcggc cgagcgcgac gcgaagcaga cccgggtgat cgccgccgcg ggcaccgacg
    25381 ccgacgccgg taccgacgcc ggtccggcgc aacgggcgta gccgagcgcg cccatgcggc
    25441 ggacggtcgg gttccgctcg acgagcactc gaagagggct cgaagtccgc tcgacgctcg
    25501 ctcgaagccg gctcgaagaa cgctcgaaag ccgcgaggag tatccgttcg cccgttgacc
    25561 tcaactccgg ttgaggttga aagataaagc gcaccagcga caacagcgtt cagcagcgtt
    25621 caccagcgtt cgccaaagtt catcagtgtt catcagcgtt cagcagagag aaggacatgc
    25681 catgaaggcg gcagttttcc aggagttcgg cggccccgag gtgctcaagg tcgaggaggt
    25741 cgagaccccc cgtcccggcg ccggcgagat ccgcgtgcgc gtcaaggccg ccggcgtgca
    25801 ggcgtacgac acggccgtcc gcgccggctg gaacccgccc ggcatgacca tctccttccc
    25861 gcagaccatc ggcaacgact tcgcgggcgt cgtcgacgag ctcggcgagg gcgtcaccga
    25921 gttcgccgtc ggcgatgagg tcctgggctg ggccctgctc tcctgctccg ccgagtacct
    25981 ggtcgtctcc gccgagcagg tcgtcgccaa gcccgccggc atgccgtggg aggtggccgg
    26041 cgcgttctcc gcctcggcgc agaccgccca caccgcgctc gaggcgctgg agatcggcgc
    26101 gggcgacacc ctgctcgtcc acgcggccgc cggcggcgtc ggcacgatcg ccgtgcagct
    26161 ggcccaggtc ctgggcgcca cggccatcgg caccgcgagc gagcgcaacc acgagtacct
    26221 gcgctccctg ggcgccaccc ccgtcaccta cggcgagggc ctcgccgacc gcgtccgcga
    26281 gctcgccccc ggcggcgtca ccgcggccct cgacggcatc ggcggcgacg ccctcgacgt
    26341 ctccgtcgag ctggtgaagg acaagaaccg catcgccacc ctcgtcgact tcggccgcgt
    26401 cgaggagctg ggcgtccgcg ccgtcttcag ccagcgggcc aaggagcgcc tcgccgggct
    26461 caccgccctc tacgccgagg gcaagctgcg cgtggaggtc tccaagacct tcccgctgga
    26521 gcaggccgcg gacgcgcacc gcgagatgga gaccggccac gtgcgcggga agatcgtcat
    26581 caccgtcggc tgaacgatcg atcgaacgat caaccgagga gacctgccat gaagatcgag
    26641 atctactccg acgtcctgtg cccgtggtgc tacatcggca agcgccggat agccgccgcc
    26701 ctggacggct tcgcccaccg cgacgagctg gagatcgtct ggcgcagctt cgagctcgcg
    26761 ccgggcgagg gcagcgagcc cggcccgacg gcggccgagg ccatggccga gtggacggcc
    26821 ccggacgtgc tgccgggccg gatcgaactg atcaagtccc agggccggca ggagggtctg
    26881 gagctcaacc tccacaagtc ccgccccgtg ggcaccttcg acgcgcaccg cctcacccac
    26941 ttcgcggccg agcgcggcct gctggagccg gtcatggagc ggctgttcca cgcgtaccac
    27001 accgaggccc tgaacgtcgc ggaccgcgag gtgctggtgc ggctggcggg cgaggccggg
    27061 ctggacgagg ccgaggtccg cgaggtgctg gagagcgacc gctacgcgga cgccgtggtc
    27121 gccgacggga accgcgcccg ccagttcaac gtgacgggcg tgccgtccgt cgtcatcgac
    27181 ggccgcatgc cggtctccgg cgtgcaggcg cccgagaagc tgctcacctt catcgagcgg
    27241 gcgtgggagc gggcgcacaa ggagcccgcg gcgtccgtct gaggccgccg cgaggagccg
    27301 gtggcgtccg cccgggccgc cgccacacac cgtgatctcc gcaggtccgc aagggtccgc
    27361 ggagatcctc gcaggtccgt acgagtccgc cctcaggccg aaaacccgct gccacggccg
    27421 gaattcgatc cgctctccac cggggctcca gccgcgttcc ggagtctgtt cccggcgctg
    27481 gaattgctcc acgccgtctg agagaggaaa tgcagtgcag cacaagtgga agctgacggg
    27541 cggacttgcg gcctcactgg ggcttgctct gacggggatc atgtcctcgg ccggaacggc
    27601 gagtgccgac accgcgacga agacgctcga ctacacctgc cagacccgtg tggacggcaa
    27661 ctggatcccc gtcccgtact cgcgggactt caccaccacg gcgccggcca aggtcgcgcc
    27721 gggccagacc ttcaaggtca ccttcgactc ggcccccatc aaggccgtgg cggacttcaa
    27781 caagctgctc aacaacgtga acatcgcgta caagaccccg gccaacgcca aggtcgtcgg
    27841 ctacaagctg accggtggca gcaacctcgg caccgccaag cagtgggtcg agcgcaacgg
    27901 caccaacttc aacatcaagt ccaacggcga gtgggccggc ggcgtggagt tcgacttccc
    27961 gaacctggag gtcacgctca aggccccgac cacggccggt gccaccctca ccaccggtgc
    28021 gggcggctcc agcttcgagg acacggcctt cggctggacg cgtctgcaga cgcagctgaa
    28081 cacctgggac ccgttccagt gctacgccga cccggccaag ccggtggcgt tctcgaccac
    28141 cacggtcggt tactgaccgg tcgggtgacc gccccgggcg cggctgccgg aatgcctccc
    28201 ggcagccgcg cccgggcgtc cgccgcaccg aagtccgccg caccgaagtc cgccgcaccg
    28261 aagtccgccg aacgagaacg ggcacgtgat gagcagcgca gtacagcctc cgggggacgt
    28321 cgtacagcct cccggggaca tcgtgcagcc tcccggggac gtcgtgcagc cttccgagaa
    28381 cgccgtacgg ccttgcgggg agcggaccgt cgtcgccgtc atcggcgcgg gcaccatcgg
    28441 gctcggctgg atcgccctct tcctggaccg gggactccgg gtccgggtca acagcagacg
    28501 gcccgacgcc gagcgggtgg tcagggaggg cctcgcggtc ttcgccccca ccctgccggg
    28561 cggagccgcc gacgtcggcg tgctcatgga gcacgtggag ttcgagcccg acatggcccg
    28621 cgccgtgcgc ggcgcggcgg tcgtgcagga gaacgccccc gacgacctcg ccctcaagca
    28681 ggaactcttc cgtacggtcg agcaggccgc tcccgcggaa gcgctcctcc tgtcctccac
    28741 gtccaagctg ctgcccgacg acatgggcgc gctgatggcc gagccgggac gcgtcgtcgt
    28801 gggacacccc ttcaacccgc cgcacgtcgt ccccctggtc gaggtcgtcg gcggccggca
    28861 cacccccgcc gcgctgatcg acgaggtcac ggccttctac cgggcggtgg gcaaggtccc
    28921 cgtcgtcgtc cgcaagcccg taccgcgctt cgtcgccaac cgcctgcagt ccgcgctgct
    28981 gagggagagc gtccacctcg tgcaggaggg cgtcgtgacg atggccgaac tcgacgccgt
    29041 cgtcacgcag tcgatcggcc tgcgctgggc cacggtcggg ccgttcgagg ccttccacct
    29101 gggcggcggc gagggcggcc tgcgccgctg gctgggcggc gtggcgcccg gcctggagcg
    29161 cgcctggcgc gcccccgccg tcccggccct gacgccggac gccgtcgagg cgctcggcgc
    29221 cgaggcggac cggaccttcg gcacggacta cgccgcgctg tcgcgcgccc gtgacgagaa
    29281 gcagaacgcc gtgctcgacg cgctcgcgcg gatcgacgcc cggcccgagt cactcaggga
    29341 agacgagacc atggaacccc agccccagcc ccagcctcag cccccgtccc ggcagacccc
    29401 gccgccccag cagggtgaac cgcacgtcgt ggacttctgg ttcgacccgc tgtgcccctt
    29461 cgcctggatc acctcccggt ggatcaccga ggtggccggg aaggccccgg tgaccgtccg
    29521 ctggcacgcg atgagcctgg ccctcctcaa cagcggcaag gacatgcccg aggcgcggcg
    29581 cacgatgctc gacctctact ggggcccggt ccgggtgctg gccgccgccc gcgccgccca
    29641 cggcgacgcc gtcaccggcc cgctctacac ggcgatgggc tcccgcttcc acgcccccgg
    29701 cggcatcttc gagcccgtcc gcaccgcccc ggccgaggag ttccgcgcgg cgatgatcga
    29761 ggggctcggc aggacgcgcc cgggcatcga ggcggccctg gccgagaccg ggctgcccgc
    29821 cgggctgatc gacgccatgg acgacgaccg ctgggacgac gagctgcgcg cctcgcacgc
    29881 ccgggtgccc tcggacggcc tcggccagga gctgatcggc gtcccgacga tctccgtcga
    29941 cggcggcgcg ggccagttcg gcccggtcct gacggagata ccgcgcggcg agcgggcggt
    30001 acggctctgg gaggccttcc ggaccctggc cggcgacccg gcgttcttcg agctgaagca
    30061 gagcacgggg cgcaccgagc ccctgaccca ctgactcact gccccaccga tccgacgatg
    30121 cgaccgatca actggaggaa tctcagatgc gtgtgatccg tatccgtgag ttcgggggcc
    30181 cggaggtcat gcgggtcgag gagacccccg tgccgcagcc gggccccggc gaggtgctga
    30241 tcgccgccga ggcgatcagc gtgggcttcg cgcagacgca gatgcggcgc aacatcttcc
    30301 ccgcgccgat gtggcggccc gagttcccga tcgtgctcgg cggcgacgtc atcgggcgcg
    30361 tcgcgggcgt gggcgccggg gtgacgggct tccgcgaggg cgaccgcgtc ggcgcgttca
    30421 ccctccacgg ggcgtacgcc gactacgtgg tcgtcgacgc ggccacggtc ctgcccgtgc
    30481 cggagggcct cgacgccgcg caggccaccg ccctcccctc gcccggcccc atcggcaccg
    30541 gcaccctggg cacggcgaac ctgcgcccgg gcgagagcgt cctggtgcac gccgcgtccg
    30601 gcggcatcgg ccacctgagc gtgcagtggg ccaaggccca cggcgccggc ccggtcatcg
    30661 ccaccgcgag ctcggccgag aagctcgact tcgcccgcgc cctcggcgcc gacgtcgtcg
    30721 tcgactacag ccgcgagggc tgggccgacg aggtccgcga ggccaccggc ggcgccggcg
    30781 tcgacatcat cctcgacagc atcggcggcg acgtcctccg ccagggcgtc ggcctgctgg
    30841 cgcccttcgg ccgcctggtc ttctacggct ccgcgggcgg cgggctggag atcccccgga
    30901 tctcccccat ggaactcatc gagatgaagt tcatcaccgg cttcgccctc tcccgctggc
    30961 gcgccgcccg cccgaaggag tacctcgcca accacgagga actggccgcc ggcctcgccg
    31021 acggcacgat ccggcacgcg gtgcacgcca cgtaccccct cgaagaggtc ggccgggccc
    31081 acgaggagat cgagtcccgg gcccacatcg ggcgcatcgt gctgctgccc tgacaccccc
    31141 gcaccgagat tggaaccgcc ttgccggaca cgaacgccca gcaccccacc cgcctcgccg
    31201 tgatcgtcgg cagcacccgc aaggaccgct tcggtccggt cgtcgccgac tggttcaccg
    31261 cccacgcccg tgagcgcgcc gacctggacg tcgacgtcat cgacctggcc gaggccgacc
    31321 tgccgcacgt cctggaggga cccggcgagg acggcacgca cccctcggcg gcggtgcgcg
    31381 ccttcgcggc gcggatcgac cgggccgacg tcttcgccgt catcacgccc gagtacaacc
    31441 gcggttaccc cgccgcgctc aagcaggcca tcgactcggt gtacaccgag ttccacgcca
    31501 agccggtcgg cttcgtcagc tactccggcg gcgcgaccgg cggcgtgcgc gccgtcgagc
    31561 agctccggtc ggtcttcgcc gagctccaca ccgtgacgct gcgggacggc gtggccatcc
    31621 cctccgccta cgccgccttc gacgacgacg ggcagccgcg ggacaccgag ggcgtcaacg
    31681 gcgccgcgaa gaagctgctc gaccagctgc tgtggtgggc cgtcgccctg cgcgaggcgc
    31741 gggccaagtc cccgtacgcc gcctgagggt ccgcgggccg cggcgaaccc gggccgcggc
    31801 gccgtcgcgt gtccgcacgc ccggccggcc gggaaagccc gcccgggaaa gcccgcccgg
    31861 gaaagcccgc ccagtagagc ccgcccggga aagcctgctc gaaaacgtcc gacatcccac
    31921 gtccgacatc ccacgttcca cgtcccacgt cctagggagc gatgtgtccc gccgcctgtt
    31981 cacctcggag tccgtgaccg agggtcaccc cgacaagatc gctgaccaga tcagcgacac
    32041 gatcctcgac gccctgctca aggaggaccc gacctcccgc gtggccgtcg agaccctgat
    32101 caccaccggc ctggtgcatg tggccggcga ggtcacgacg aaggcctacg cgccgatcgc
    32161 ctcgctcgtg cgcaacaaga tcctggacat cggctacgac tcctcgacga agggcttcga
    32221 cggttcttcg tgtggtgtgt cggtgtcgat cggcgcgcag tcgccggaca ttgcgcaggg
    32281 tgtggacgcg gcctacgagg cgcgtgtgga gggtgacgag gacgagctgg accggcaggg
    32341 tgcgggcgac cagggtttga tgttcggcta cgcgtgcgac gagacgccgg agctgatgcc
    32401 gctgccgatc cacctggccc accggctctc gcggcgtctg tcggaggtcc gcaagaacgg
    32461 gaccatcccc tacctgcgtc ccgacggcaa gacgcaggtg acgatcgaat acgacggtga
    32521 caaggccgtc cgcctcgaca cggtcgtggt gtcctcgcag catgccgcgg acgtcgacct
    32581 ggacgccctc ctggctccgg acgtccggaa gttcgtggtg gagcacgtcc tcaaggagct
    32641 cgtcgaggac ggcatcgcgc tggacaccga tggctaccgg ctgctggtga acccgaccgg
    32701 tcgcttcgag atcggcggcc cgatgggcga tgcgggtctg acgggccgga agatcatcat
    32761 cgacacgtac ggcggcatgg cccgtcacgg tggcggtgcc ttctcgggca aggacccgtc
    32821 caaggtggac cgctcggcgg cgtacgcgat gcgctgggtg gccaagaacg tcgtggcggc
    32881 gggtctggcg tcgcggtgtg aggtgcaggt cgcgtacgcg atcggcaagg ccgagccggt
    32941 gggtctgttc gtggagacct tcggtacgaa cacgatcgac acggacaaga tcgagaacgc
    33001 gatcgccgag gtcttcgacc tccgcccggc cgcgatcatc cgtgacctgg acctgctgcg
    33061 tccggtctac gcgcagaccg ccgcgtacgg ccacttcggc cgtgagctgc cggacttcac
    33121 ctgggagcgc acggaccgcg tggaggccct gaagaaggcc gccggcctct agtcggaccg
    33181 ggggcggggc accccgcccc gcccccgccg tctgcccgcc cccacccgta ccgcaggacc
    33241 caccgcccct cgccccgagc ccagggagag aaccccgtgc gcatcgccgt gaccggttcg
    33301 atagccaccg accacctgat ggtctatccc ggacgcttca ccgagcagct catccccgac
    33361 cagctcgaca aggtgtccct gtccttcctc gccgacacgc tggagatccg gcgcggcggc
    33421 gtcgccgcca acatcgcctt cggcatgggc cggctcggcc tgcgcccggt gctgctgggc
    33481 gcggcgggtg cggacttcgc cgagtacggg cagtggctga gcgccaacgg ggcggacacc
    33541 gactcggtgc acatcagcga gtccctgcac acggcccgct tcgtctgcac cacggacgcc
    33601 gaccagaacc agatcgccac cttctacgcc ggggccatgg ccgaggcccg cgagatcgag
    33661 ctggcgccgg tggcgcggcg ggtcggcggc ctcgacctgg tcgtcgtcgc ccccaacgac
    33721 ccggccgcga tgctccggca cacggacgag tgccgggcca cgggcctgcc cttcgccgcc
    33781 gacccctcgc agcagctcgc ccggctgggc gcggaggaga cccgccggct ggtggacggc
    33841 gcccgcttcc tgttcaccaa cgagtacgag gccgcgctgc tgcaggagcg caccggctgg
    33901 acggcggcag aggtcctcgc gcgcgtgggc acctgggtga ccacgctggg ggagaacggt
    33961 gtggtgatca cggaggaggg cggcgcggag ctgcgcgttc ccgccgtccc gaccggtgac
    34021 atcaaggacc cgacgggcgt cggcgacgcc ttccgggcgg ggttcctcgc cggtgtcgtg
    34081 tggcagcagc cgtacgagcg ggccgcgcag ctgggctgcg cgctggccac gctggtgctg
    34141 gagtccgtcg gcacgcagga gtacaagccg gcgtggagcg acctgctggc ccgcatcgag
    34201 gacgcctacg gggcgcaggc cgcacgggag atcgccccgc atctgccgca tcttccggac
    34261 ctgccccatc gtccgcacct ggtggatccg tcggccgcgg gcagcgcgtc gtgaccgcga
    34321 tcccgactga tgccgccacg cgagccgccg gg
//
