LOCUS       BGC0001962              7027 bp    DNA     linear   BCT 19-FEB-2019
DEFINITION  Cyanobium sp. LEGE 06113 phosphate ABC transporter permease subunit
            PstC and ABC-type phosphate transport system protein genes, complete
            cds; hid gene cluster, complete sequence; and PAP-fibrillin and
            beta-lactamase genes, complete cds.
ACCESSION   BGC0001962
VERSION     BGC0001962
KEYWORDS    .
SOURCE      Cyanobium sp. LEGE 06113
  ORGANISM  Cyanobium sp. LEGE 06113
            Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
            Prochlorococcaceae; Cyanobium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:37:13
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7027
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..879)
                     /codon_start=1
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="QBC65474.1"
                     /transl_table=11
                     /translation="MTSAADRLLLWSLRLTAVLACSIVVWILAFLLGEALPALGALGPL
                     RWLGDPSWHPTVGATEGHFGLAPMLLATAASSAGAVLLATPVALGSALFCHSYGPPRWS
                     GVYRRLVQLLAGIPSVVFGFWGLVELTPRIARWQPPGQSLLAGILILALMILPTISLLM
                     ESALAELPASYRQAAAALGLSPWASLRRVLLPAAAPGLASAVLLGSARAIGETMAVLMV
                     SGNVVQLPGNLFAPVRTLTANIALELGYALDLHRSALFVGGLVLLVLVAALVAVAEGLA
                     ATSQAGGRAHG"
     source          1..7027
                     /country="Portugal: Praia da Aguda, Arcozelo"
                     /db_xref="taxon:1297573"
                     /isolation_source="intertidal zone, Sabellaria sp. reef,
                     epipsamic"
                     /mol_type="genomic DNA"
                     /organism="Cyanobium sp. LEGE 06113"
                     /strain="LEGE 06113"
     protocluster    1..7027
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[3836:4970]"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3837..4970
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     cand_cluster    1..7027
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..7027
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001962"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..7027
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             complement(876..1661)
                     /codon_start=1
                     /product="ABC-type phosphate transport system protein"
                     /protein_id="QBC65475.1"
                     /transl_table=11
                     /translation="MAGLLVGCSSAASPPRLTLTGSSSVAPLAGEIARRFEASHPGVRI
                     DVQTGGSSRGLADLRRGSADIGMVSRALNSSEADLQATTIALDGVAVIVNSSNPVQTLS
                     DEQIRGIFTGRIADWSELGGSPAPITVVTKAEGRSTLEVFLDHFQLDNQAIRASVVIGD
                     NQQGLRTVAGDPGAIAYVSIGAATLEAQRGLAIRLLPMAGVAPTLTNVAQRRFPLARPL
                     NLVSKPDHSNPLARDFLRFATAPANDDLLAREAVVAPAR"
     CDS             1850..2650
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1269:hypothetical
                     protein (Score: 217.7; E-value: 2.4e-66)"
                     /gene_kind="other"
                     /note="HidA"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="QBC65478.1"
                     /transl_table=11
                     /translation="MGGRSAELIDTLSVPLAELWAGLPQRQLRAEVMDQPELDPVVHRD
                     ALRGLARINTLTRSAACFAPALRQLALRRPGQRLRLLDVACGSGDSLRALGRLGRRLGL
                     DLELHGCDLSAEAMAMAGDLALAEGVEAHFFQADALGEPLPGGYQLVVCSLFLHHLSRA
                     QAQTLLRHMAAATDDQLLLHDLLRTRLDLLLTWAGTRLLSRSPVVHVDGPLSVGGAFRL
                     DEVAALAAAAGLEGAQLRRFWPERFLLSWRRGSGEAGSAAAPAG"
     misc_feature    1850..4970
                     /note="hid gene cluster"
     CDS             2824..3840
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161:oxidoreductase (Score: 210.2; E-value: 7.6e-64)"
                     /gene_kind="biosynthetic-additional"
                     /note="HidB"
                     /product="flavin-dependent oxidoreductase"
                     /protein_id="QBC65479.1"
                     /transl_table=11
                     /translation="MGLDHIAAAGVPLEQLQLGVAGRSLPLPLRQGRALSRHHMDQALL
                     QAAADAGAAVRFGSRAELGPVQPAWRELVLHRRGGKERLRAAVVLLAAGLTHRSPRQEP
                     ALRTRIAPGSRVGAGCVLEGDAAGPPEAYPSGVIHMAVGRGGYVGAVRVETGALNLACA
                     FDPAALRRAGGPAPLAGAILAEAGFPPLVEQPAEQSWQLTAPLTRRTRPLAGHRLLLLG
                     DAAGYVEPFTGEGMGWALTAALACLPLVRRGLVEWDPALADDWHQQHRHWVARRQTVCR
                     GLALLLRHPTATAALQRTAALLPSVARPLLQRVQHTALPPLISTPAAPSPLEAAPWR"
     CDS             3837..4970
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:chalcone and stilbene synthase domain protein
                     (Score: 373; E-value: 1.9e-113)"
                     /gene_kind="biosynthetic"
                     /note="HidC"
                     /product="type III polyketide synthase"
                     /protein_id="QBC65480.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 1.7e-27,
                     bitscore: 85.2, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 1e-27, bitscore:
                     86.0, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLLGLGTAVPELRLSQAEALARAPQMRGASPRQQRLLRRIYERC
                     GVENRHCITPDDDPNPSTAVRMRRYGPAALELGLQASRAALAEAGVAGTAITHLVTVSC
                     TGFAAPGFDLALVAGLPLAADVARTHVGFMGCHGALNGLRVARAFVEADPRACVLLCAV
                     ELCSLHLQEGWNPDHIVANALFADGAAAVVAVAGQGSPGREAPRQGGLQLLASGSTVIP
                     HTAGAMAWLIEDHGFSMALSARVPAVIQAQLRPWLDGWLAGLGLSLEAIRHWAVHPGGP
                     RILTAVLQSAELDDERLAVSRAVLRRFGNMSSATLLFILQRLRQGQGPGPGPCLALGFG
                     PGLTVEAALFGVDGATLARDPTPPEALREAVDCDEQL"
     CDS             4957..5553
                     /codon_start=1
                     /product="PAP-fibrillin"
                     /protein_id="QBC65476.1"
                     /transl_table=11
                     /translation="MSNSERLQLLSLLQEGPRGSAHRRDGEVRPLITALEASSPADLQS
                     DAARQQLEGVWELRWSSSSQPYLKASPWLQNLQLLAPSQGRALNLLLPAGPLAPLGGIA
                     VEARIAISSSQRVEVRFQRGGWLGPAVGQTRLQLLRRVTPGFPAWLDITVLDDQLRLCR
                     GNAGTLFALLRRDDLSLEALLPAPAAVAASPSPGC"
     CDS             complement(5489..7027)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 202.9; E-value: 1.2e-61)"
                     /gene_kind="biosynthetic-additional"
                     /product="beta-lactamase"
                     /protein_id="QBC65477.1"
                     /transl_table=11
                     /translation="MPGLLGLAIGGPSLAAAPAASPASTPSAGLTTAQLDRALEQLPDL
                     ITTAMQRTGVPGIAAVVVHGDATVFLHGFGSRRLGSTEPVDADTVFQLASVSKPITSSA
                     IAAVVSQGGISWDTPVMQHLPETVIGGRAIGAKVTLRDLLSHRSGLPDHAGDELEDIGF
                     DRATVLARLGLLDTGNRFRADYAYTNFGFTAAAEATARATGRPWHELTREQLFGPLGMT
                     RTSSLHADFIGHRNRADLHQLSNGTWTLSPGRQSDAQSPAGGVSSTVRDLAAWMKKQLS
                     AEASSALAETHRPQMISTAPADPTRDQAQLYGLGWNVGRDRTNAVRLSHSGAFNLGAAT
                     AVTLLPAEGLGIAVLTNGSPIGVPESISAAFLDLVQTGEVRMDYLPVLAEVFAELLAST
                     YPVVGAPPAAPALPLEGYTGTYRNAYVGTVEVVPAGNGLQLLLGPDRLSRPLTSLGQHR
                     FSYEPIGENNTGPSAVTFSLGEDGRPTTVRIDNLNTQGMGTLQRLREPAAGPPG"
ORIGIN
        1 tcagccatgg gcccgccctc cggcctggct cgtcgcagcc agcccctcgg ccacggccac
       61 cagagctgcc accagcacca gcaacaccag cccccccacg aacagggccg agcggtgcag
      121 gtccagggca tagcccagtt ccagggcgat gttggccgtg agggtgcgca ccggagcgaa
      181 aaggttgccc ggcagctgca ccacgttgcc gctgaccatc agcaccgcca tggtttcgcc
      241 gatggcgcgg gcgctgccga gcagcaccgc tgaggcgagg ccgggggcgg ccgcgggcag
      301 cagcacccgg cgcaggctgg cccagggact gagacccagg gccgccgcgg cctgccggta
      361 actcgccggc agctccgcca gggccgactc catcagcagg ctgatggtgg gcaggatcat
      421 cagggccagg atcaggatcc ccgccagcag gctctggccc ggcggctgcc agcgggcgat
      481 ccggggcgtc agttccacca gcccccagaa gccgaacacc accgagggaa tgcccgccag
      541 cagctgcacc agacgccggt acaccccgct ccagcggggt ggcccatagc tgtggcagaa
      601 cagggcggag ccgagcgcca ccggggtggc cagcagcacg gcaccggcac tgctggccgc
      661 cgtggcgagc agcatcggcg ccagaccgaa gtggccctcc gtggcgccga ctgtcgggtg
      721 ccagctggga tcaccgagcc agcggagcgg gccgagggcc cccagggccg gcagggcctc
      781 ccccagcaga aaggccagga tccagaccac gatcgagcag gccagcacgg ccgtcaggcg
      841 caggctccag agcagcagcc ggtcggcggc gctggtcatc gggccggcgc caccacggct
      901 tcccgggcca gcaggtcatc gttggccggg gcggtggcaa agcgcaggaa gtccctggcc
      961 aggggattgg agtgatcggg tttgctcacc aggttgagcg gccgggccag ggggaaacgc
     1021 cgctgggcca cgttggtcag ggtgggggcc acgccggcca tcggcagcag ccggatcgcc
     1081 aggccccgct gggcttccag ggtcgccgcc ccgatcgaca cgtaggcgat ggcgccggga
     1141 tcgcccgcca ccgtgcgcag cccctgctgg ttatcgccga tcaccacgct ggcccggatg
     1201 gcctggttgt cgagttggaa gtggtcgagg aacacctcca gggtggagcg cccctcggcc
     1261 ttggtcacca ccgtgatcgg cgcggggctg ccgcccagct ccgaccagtc ggcgatgcgg
     1321 cccgtgaaga tgccccggat ctgctcatcg ctcagggtct gcaccgggtt gctgctgttc
     1381 acgatcacgg cgacgccgtc cagggcgatg gtggtggcct ggaggtcggc ctcgctgctg
     1441 ttcaaggccc gcgacaccat gccgatgtcg gcgctgcccc ggcgcaggtc cgccaggccg
     1501 cgggaggacc cgccggtctg cacgtcgatg cgcacgccgg gatggctggc ctcgaagcgg
     1561 cgggcgatct ccccggccag gggagccacg ctgctggagc ccgtgagggt gagccgtggc
     1621 ggtgaggcag ccgaggagca gcccaccagc agcccggcca tggcagctat tgcggccagg
     1681 atccctctgg gggccagggc gctgctggcg gttggagcgt gcactggcac ggctggtgtc
     1741 gacgggggct ctggaagtac tggcgacggc ggcgatcgga tgcggcctgg tctgccgcgg
     1801 ggaggaggtt cctagggttc ggccgttgtg acacaggcag ggctcaggga tgggtgggcg
     1861 ctcggccgag ctgatcgaca ccctctcggt gcccctggct gagctgtggg caggcctgcc
     1921 ccagcggcag ctgcgcgcgg aggtgatgga tcagccggag ctcgatccgg tggtgcaccg
     1981 cgatgccctg cgcggtctgg cccgcatcaa caccctcacc cgcagtgcgg cctgcttcgc
     2041 tccggccctg cgccagctgg ccctgcgcag gcccggccag cggctgcggc tgctggatgt
     2101 ggcctgcggc agcggcgaca gcctgcgcgc cctgggccgc ctcggccggc gcctgggcct
     2161 cgatctggag ctgcacggct gcgacctcag tgccgaggcc atggccatgg ctggcgatct
     2221 ggcgcttgcc gagggggtgg aggcccactt cttccaggcc gatgccctgg gcgagccgct
     2281 gcccggcggc tatcagctgg tggtctgctc tctgtttctg catcacctca gcagggccca
     2341 ggcccagacc ctgttgcgtc acatggcggc cgccaccgac gatcagctgc tgctgcacga
     2401 cctgctgcgc acccgcctcg atctgctgct cacctgggcc ggcaccaggc tgttgagccg
     2461 ttcgccggtg gtgcatgtgg atgggcccct ctcggtgggc ggcgccttcc ggctcgacga
     2521 ggtggcggcc ctggccgccg ccgccggcct ggagggggcc cagctgcggc ggttctggcc
     2581 ggagcggttc ctgctctcct ggcgccgggg atcgggcgag gccggctccg ccgcggctcc
     2641 ggctggatga ggctgccgtg atctgggacg tgctggtggt gggcggcggc cggcggggcg
     2701 gcggcggccc tgggcctggc ccgccagggg gcgcgggtgc tggtggtgga gcagcgccag
     2761 tttccccgct ggaaagtgtg tggcgcctgc ctcagccccc aggccctggc cgtgctgcag
     2821 gccatgggtt tggaccacat cgccgcggcc ggtgtgcccc tggagcagct ccagctgggg
     2881 gtggccggcc gcagcctgcc cctgccgctg cgccaggggc gtgccctgtc gcgccaccac
     2941 atggatcagg ccctgctgca ggccgccgct gacgccgggg cggcggtgcg cttcggcagc
     3001 cgggctgagc tggggccggt gcagcccgcc tggcgggagc tggtgctgca ccggcgcggc
     3061 gggaaggagc gcctgcgggc tgccgtggtg ctgctggcgg cgggcctcac gcaccggagc
     3121 ccccggcagg agccggccct gcgcacccgg attgcccccg gcagccgggt gggggcgggc
     3181 tgcgtgctgg aaggcgatgc cgccggcccg ccggaggctt atccctctgg ggtgatccac
     3241 atggcggtgg gccggggcgg ctatgtgggg gcggtgcggg tggagaccgg cgccctcaac
     3301 ctggcctgcg ccttcgatcc cgccgccctt cgccgcgccg gtgggccggc gcccctggcc
     3361 ggggcgatcc tggccgaagc gggcttcccc cccctggtcg aacagcccgc tgaacagtcc
     3421 tggcagctca ccgcgcccct gacgcgccgc acccggcccc tggccggcca tcgcctgctc
     3481 ctgctcgggg atgccgccgg ctatgtggag cccttcacgg gcgagggcat gggctgggcg
     3541 ctcaccgcgg cgctggcctg cctgcccctg gtgcggcggg ggttggtgga gtgggacccg
     3601 gccctcgcgg atgactggca ccagcagcac cgccactggg tggcgcgccg gcagacggtc
     3661 tgccgcggcc tggccctgct gctgcgtcat cccacggcca ccgcggcgct gcagcgcacc
     3721 gccgccctgc tgccgtccgt ggcgaggccg ctgctgcagc gggtgcagca caccgctctg
     3781 ccgccgctga tctccacccc agcggcgcct tcccccctgg aggcggcgcc gtggcgatga
     3841 ccctgctcgg cctcggcacg gcggtgccgg agctgcggct cagccaggct gaggccctgg
     3901 cccgcgcccc ccagatgcgc ggggccagcc cacgccagca gcggctgctg cgccgcatct
     3961 acgagcgctg cggggtggag aaccgccact gcatcacccc cgatgacgac cccaacccca
     4021 gcaccgccgt gcgcatgcgg cgctatggcc ccgcggccct ggagctggga ctgcaggcca
     4081 gccgcgcggc cctggccgag gccggggtgg cgggaaccgc catcacccac ctggtcacgg
     4141 tgtcgtgcac gggctttgcg gcgccgggct ttgacctggc tctggtggcc ggtctgcccc
     4201 tggcggcgga cgtggcccgc acccatgtgg gcttcatggg ctgccacggc gccctcaatg
     4261 gcctgcgggt ggcgcgggcc ttcgtggagg ccgatccccg ggcctgcgtg ctgctctgcg
     4321 ccgtggagct gtgcagcctg cacctgcagg agggctggaa ccccgaccac atcgtggcca
     4381 acgccctgtt cgccgacggc gccgccgccg tggtggccgt ggcggggcag ggcagtccag
     4441 gcagggaggc gcccaggcag ggaggcctgc agctgctggc cagtggctcc accgtgattc
     4501 cgcacacggc cggggcgatg gcctggctca tcgaggacca cggcttctcc atggcgctct
     4561 cggcgcgggt gccggcagtg atccaggcgc agctgcggcc ctggctggat ggctggctgg
     4621 ccgggctggg cctcagtctc gaggcgattc gccactgggc cgtgcatccc ggcggtcccc
     4681 gcatcctcac ggcggtgctg cagagcgccg agctcgatga tgagcgcctg gccgtgtcgc
     4741 gggcggtgct gcgccggttc ggcaacatgt cgtccgccac cctgctgttc atcctgcagc
     4801 ggttgcggca gggacagggc cccggcccag gcccctgcct ggccctggga ttcggtccgg
     4861 ggctcaccgt ggaagcagcc ctgttcgggg tcgatggcgc cacactggcc cgtgacccca
     4921 cacccccaga ggccctccgg gaggccgtcg actgcgatga gcaactctga gcggctgcag
     4981 ctcctctccc tgctgcagga gggcccccgg ggcagcgccc accgccgtga tggcgaggtg
     5041 cggccgttga tcacggccct ggaggcctcc tcgccggccg atctccagag cgatgcagcc
     5101 cggcagcagt tggagggggt gtgggagctg cgctggagca gcagctccca gccctacctc
     5161 aaggcctccc cctggctgca gaacctgcaa ctgctggccc cctcccaggg gagggccttg
     5221 aacctgttgc tgccggcggg gcccctggcc ccgctcgggg ggatcgcggt ggaggcgcgc
     5281 atcgccatca gctcgtccca gagggtggag gtgcgtttcc agcggggcgg ctggctgggg
     5341 cccgccgtgg gccagacccg gctgcagctg ctgcgccggg tgacgccagg cttcccggcc
     5401 tggctcgaca tcacggtgct cgacgatcag ctgcgcctct gccgcggcaa tgcgggaacc
     5461 ctgtttgccc tgctgcgccg cgacgacctc agcctggagg ccctgctgcc ggctcccgca
     5521 gccgttgcag cgtccccatc ccctgggtgt tgaggttgtc gatgcgcacc gtggtgggcc
     5581 gaccatcctc ccccaggctg aacgtaacgg cgctgggccc ggtgttgttc tcgccgatgg
     5641 gttcatagga gaaccgatgc tgccccaggg aggtgagggg ccggctgagg cgatcgggtc
     5701 ccaggagcag ctgcaggcca ttcccggccg gcaccacctc caccgtgccg acgtaggcat
     5761 tgcgataggt gcctgtgtag ccctccaggg gcagggccgg tgccgcgggc ggtgccccga
     5821 ccaccggata ggtggaggcg agcagttcgg cgaacacctc cgccagcacc gggaggtagt
     5881 ccatgcgcac ctccccggtc tgcaccaggt cgaggaaggc ggcgctgatc gattccggca
     5941 ctccgatcgg cgagccattg gtgagcacgg cgatccccag cccctcggcc ggcagcaggg
     6001 taaccgccgt ggcggctccg aggttgaacg cgccgctgtg gctgagcctg accgcatttg
     6061 tccggtcgcg gcccacgttc cagcccaggc cgtagagctg ggcctgatcc ctggtggggt
     6121 cggcgggggc ggtgctgatc atctggggcc ggtgggtttc ggccagcgct gagctggcct
     6181 cggcgctgag ctgcttcttc atccaggcgg ccaggtcgcg caccgtggaa ctgacgcccc
     6241 cggccggcga ctgggcatcc gactggcgac cggggctcag cgtccaggtg ccgttgctga
     6301 gctggtggag gtcggcgcgg ttgcggtggc cgatgaagtc ggcatgcagg gagctggtgc
     6361 gggtcatgcc gaggggcccg aacagctgct cccgggtgag ctcgtgccag ggacgtcccg
     6421 tggcgcgagc tgtcgcttcg gcggcggcgg tgaagccgaa gttggtgtag gcgtaatcag
     6481 cgcgaaagcg gttgcccgta tccagcagcc ccaggcgcgc cagcaccgtg gcccgatcga
     6541 agccgatgtc ctcgagctca tcgccggcat ggtcgggcag gccactgcga tgggagagca
     6601 gatcccgcag ggtcaccttc gccccgatcg cccggccgcc gatcaccgtt tcgggcaggt
     6661 gctgcatcac cggggtgtcc cagctgatcc ccccctggct caccaccgcg gcgatggcgc
     6721 tgctggtgat cggtttcgac accgaggcga gctggaacac cgtgtcggca tccaccggct
     6781 cggtgctgcc caggcgacgg ctgccgaagc cgtgcagaaa cacggtggcg tcaccgtgaa
     6841 ccaccacagc ggcgatccca ggcaccccgg tgcgctgcat ggccgtggtg atcaggtcgg
     6901 gcagctgctc cagggcccga tcgagctggg ctgtggtcag ccctgccgat ggcgtggatg
     6961 ccggtgaggc agccggagca gccgccaggg atggtccgcc gatcgctagc cccagcagcc
     7021 caggcat
//
