LOCUS       BGC0001965             30490 bp    DNA     linear   BCT 18-NOV-2018
DEFINITION  Streptomyces albus subsp. chlorinus strain LW030448 nybomycin
            biosynthetic gene cluster, complete sequence.
ACCESSION   BGC0001965
VERSION     BGC0001965
KEYWORDS    .
SOURCE      Streptomyces albus subsp. chlorinus
  ORGANISM  Streptomyces albus subsp. chlorinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 16:37:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 30490
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..510)
                     /gene="orf-04"
     CDS             complement(1..510)
                     /codon_start=1
                     /gene="orf-04"
                     /product="hypothetical protein"
                     /protein_id="AYV61398.1"
                     /transl_table=11
                     /translation="MAKGKAEAGAVTAPVVVFDLDGTLADVRHRLPLLQRRPRDWEAFF
                     AAAVHDPPLAEGVALAREKAREGELAYVTGRPERCRADTLAWLREQDLPGDRLLMRAER
                     DRRPARVAKPELLRHLARERPVLLVVDDDAQVCLAYERAGFPVLRADWMSQEPVLEAVQ
                     EAEGRT"
     source          1..30490
                     /country="USA"
                     /culture_collection="NRRL:B-24108"
                     /db_xref="taxon:337066"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces albus subsp. chlorinus"
                     /strain="LW030448"
                     /sub_species="chlorinus"
     misc_feature    1..30490
                     /note="nybomycin biosynthetic gene cluster"
     subregion       1..30490
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..30490
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            659..1006
                     /gene="orf-03"
     CDS             659..1006
                     /codon_start=1
                     /gene="orf-03"
                     /product="hypothetical protein"
                     /protein_id="AYV61399.1"
                     /transl_table=11
                     /translation="MTENLGNYAPTAGHTPDADLTGYHVEAPDGRAGTVDENSTEIGSG
                     YLVVDTGPWIFGKKVLLPAGAVLGISNADRTVRVALSREQVKAAPEFDEDRHLGDPRHR
                     DQLGGRHSRGH"
     gene            complement(1160..2428)
                     /gene="orf-02"
     CDS             complement(1160..2428)
                     /codon_start=1
                     /gene="orf-02"
                     /product="hypothetical protein"
                     /protein_id="AYV61400.1"
                     /transl_table=11
                     /translation="MTLVNREPDCIALLDDPTDGPGPETTGRPALDRSVAELSPVVFAS
                     LPRADQRRKGLMYLRGLLGATGRKSVRNIAAFLGDQVNDQGLHHFINDSTWEWDPMREA
                     LGRHVLQRLPPRAYVVHPLLIPKSGTHSAGVTRTFSWERGQAVTAQQVTGVWGVTAQTA
                     HPLNWQLHLPSQSPRGTPDDCRGTVPGTDPAAWRTPEEAMVNAYVETAARLSLPRRPVV
                     LNAERLDGIKLVARLGAAGLRHVSKIAPDTWLLPNDPSLPGWGDSPLQASRIARMARAG
                     RNRVALIPSGTPDTPELVVTARVRLPAVREASGQRGTGNGDLLLIGVGGGRSRWPEELW
                     LTDMARADHSALLRLVGLSRRVERQGVPLAERVGIRDFVGRSYAGWNRHATLASVAHAA
                     TELAGLRPDADPLAARGWGRACL"
     gene            2432..3322
                     /gene="orf-01"
     CDS             2432..3322
                     /codon_start=1
                     /gene="orf-01"
                     /product="hypothetical protein"
                     /protein_id="AYV61401.1"
                     /transl_table=11
                     /translation="MPPGGCAVRFPDRARACAVVIDVVSGQVRGRIRAWGLPVGPAGKG
                     PPGPAARCPCPGPGLRRGTTGTWARRECRARARRYGAPGRARARPPGPRKEAPVRPGGA
                     CGVVGARRRRSGARWWVGVAVTCPVRGYRLPGLGPARQGRRGERVREERAPACGCALRG
                     GPSRSRTERKRRTERRGTVRAAGTAGDAGGSVTPSREGGAWRAAVGTDARARRGRWGGT
                     APGFGQFPRCSVHVHFSPYFSGPGSIGRRNEGANSCGYHVYKNPQPVLPPFPKAAKIQT
                     HGRCAAQGRQRVSWS"
     gene            complement(3807..5234)
                     /gene="nybA"
     CDS             complement(3807..5234)
                     /codon_start=1
                     /gene="nybA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 206.8; E-value: 1e-62)"
                     /gene_kind="biosynthetic-additional"
                     /product="3-carboxy-ciscis-muconate cycloisomerase"
                     /protein_id="AYV61402.1"
                     /transl_table=11
                     /translation="MSTPPARAATAGTAPPPPAPHVLDAGLLSPVRAGTPVERAVSDSA
                     WLQAMLDAEAALARAQARLGLVPAHAAEVITRTARAGRFDPRELAVRARESANPVVSLA
                     GALTRAVAEADPAAAEYVHRGSTSQDIFDTAAMLVSRDALRLLRADLARIADALARLAR
                     AHRDTVLPGRTLALHAVPTTFGLKAAGWRRAVLDADARAATVLAALPVSLGGAAGTLAG
                     YVEHGADPERLVAAFAAETGLRAPALPWHTLRTPMADLAAVLAHGAGALGKLAVDVLSL
                     TRTEVGEVVEPHVPGRGSSSAMPQKRNPVLATLVRSAALQVPALAGVLTQCMLTEDERS
                     AGAWHAEWQPLRECLRLTGGAAHTAVELAGGLTVRPARMRANLRLTEGGIVAERLVAAL
                     APLLGKAAARTLLTRATAAAAEDGRPLAVHLAGAAELAGRIPPAELDPLCDPAGYTGAA
                     AGLVDRELRPGGAEGDG"
     gene            complement(5231..7240)
                     /gene="nybB"
     CDS             complement(5231..7240)
                     /codon_start=1
                     /gene="nybB"
                     /product="FAD-binding protein"
                     /protein_id="AYV61403.1"
                     /transl_table=11
                     /translation="MLGLNTTAHEIAVIGAGPRGLAVLERLCANERARPFRSRVLVHLV
                     DSAPAGAGSVWRTGQSRHLLANTVASQITVFTDVASRIAGPIEPGPSLYEWAASLPAPP
                     AGDDAAGSTPDTAYDAATLAEAHALGPDSYPTRALCGRYFADCLRRVVEGAPAHVEIRV
                     HRSRAVAMADTLGYSGGPQGVRLENGTRLNHLDAVVLAQGHLPTRPTPHEERIASLARI
                     NHLTYLPPANPADARLDGIRAGEPVLLRGLGLCFFDYLALFTLGRGGLFDRVGGELVYR
                     PSGEEPLLYASSRRGVPFHARGENEKGAHGRHLPRLLTADHVARLRTRAARAGAGLSFA
                     QDLWPLIAREVETVYYETWLRHRRGAEAAELFAARYAACAEPAAREALVDAHRIPAADR
                     WDWAALADPARTRTFTDRDDFRAWLLDRLAEDVRQAREGNVGGPVKAALDVLRDLRNEI
                     RLAVDHGGLEGSSHRDELDRWYTPLNAFLSIGPPPRRVEEMRALVRAGVLELTGPGTRI
                     RIDTRRRAFVADSETVPGPTVRAGVLIEARLPAPDLRRTADPLLRHLRHTDACAPYRVA
                     TADGGTYETGGLAVTPRPYRLLDARGRAHPRRFAYGVPTEAVHWVTAAGIRPGVDSVTL
                     ADADAIARTVLGLGPSDAAAGATAAGVPHGEVLL"
     gene            7493..8470
                     /gene="nybC"
     CDS             7493..8470
                     /NRPS_PKS="Domain: PKS_ER (13-319). E-value: 9.8e-33.
                     Score: 105.4. Matches aSDomain:
                     nrpspksdomains_nybC_PKS_ER.1"
                     /codon_start=1
                     /gene="nybC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 233.9; E-value: 4.4e-71)"
                     /gene_kind="biosynthetic-additional"
                     /product="NADPH:quinone reductase"
                     /protein_id="AYV61404.1"
                     /sec_met_domain="ADH_N (E-value: 3.6e-13, bitscore: 40.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.2e-21, bitscore:
                     67.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAYINEFGPAHSIRFGPLPDPRPGTHEVLVDVEATTANHVDTF
                     IRSGAVETPVDFPFVVGRDLVGRVAGTGDGVTGFRVGERVWCNSLGHAGRQGAAAERAV
                     VPAERLYRLPDGVAPQTAVTVVHPAATAYLGLVTHGRLRAGQTVVVVGAAGNVGAAMLV
                     VAAAAGARVVAVARARDAAYCRDLGADVVVDREADGLGDRLARACPEGVDVWADAAGVN
                     DLTTAVRLLARRGRVVLLAGLHTTPVLPAGPLYVRDGSVVGFAITGATAGELAQAAGCV
                     NRLLAGGRLRPREVRVLPLSATAEVHRMLEAGELHGRRVALTTG"
     aSDomain        7532..8449
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nybC_PKS_ER.1"
                     /evalue="9.80E-33"
                     /label="nybC_PKS_ER.1"
                     /locus_tag="nybC"
                     /protein_end="319"
                     /protein_start="13"
                     /score="105.4"
                     /tool="antismash"
                     /translation="SIRFGPLPDPRPGTHEVLVDVEATTANHVDTFIRSGAVETPVDFP
                     FVVGRDLVGRVAGTGDGVTGFRVGERVWCNSLGHAGRQGAAAERAVVPAERLYRLPDGV
                     APQTAVTVVHPAATAYLGLVTHGRLRAGQTVVVVGAAGNVGAAMLVVAAAAGARVVAVA
                     RARDAAYCRDLGADVVVDREADGLGDRLARACPEGVDVWADAAGVNDLTTAVRLLARRG
                     RVVLLAGLHTTPVLPAGPLYVRDGSVVGFAITGATAGELAQAAGCVNRLLAGGRLRPRE
                     VRVLPLSATAEVHRMLEAGELHGRR"
     gene            complement(8545..10461)
                     /gene="nybD"
     CDS             complement(8545..10461)
                     /codon_start=1
                     /gene="nybD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 321.9; E-value:
                     1.5e-97)"
                     /gene_kind="biosynthetic-additional"
                     /note="phnA; anthranilate synthase component I"
                     /product="anthranilate synthase"
                     /protein_id="AYV61405.1"
                     /transl_table=11
                     /translation="MSARRTAADPARVLLERVLAPSPPPFALLHRPTAAGSDRVEVLTG
                     PVGPVERIADLPVPASARGPAGADVLALVPYRQLAERGFPAPDDGEPLLAMTVREQAAL
                     DRAEVLATVPDVPIRLENERFDIDDEEYAGLVRRVLAEEIGAGAGANFVVKRRFLADLT
                     GYTPATATAFFRRLLAREAGVYWTFLVHTGDRTLVGASPERHLSLADGVAVMNPISGTY
                     RYPPDGPTLSGVMDFLADRKETYELFMVVDEELKMMSRFCDADVRVVGPYLKEMARLAH
                     TEYVIEGRTERDVREILSATLFAPTVTGSPLESASRVINRYEPAGRGYYSGVAALIGRD
                     GRGRRTLDSSILIRTADITSEGRMAIGVGATLVRDSEPAAEVAETLAKATGLLSALRAE
                     PEGPLGRHPSVRSALRARNQEIARFWLDGSGPAAGRPSALDGRRVLVVDAEDTFTSMIA
                     HQLRSAGLEVTVRRFDEPYSFAEHDLVVMGPGPGSPLEVGEPRIAHLHEAVDTLLEARR
                     PFLAVCLSHQVLSHRLGLPVRRRDIPHQGVQKDIDLFGRPERVGFYNSFVAHSPSGLLT
                     PYGTGPVEVCRDAATGEVHALRGRHFAGVQFHAESVLTHDGVRILGTLLAGVLDGAGQP
                     VRS"
     gene            complement(10458..11141)
                     /gene="nybE"
     CDS             complement(10458..11141)
                     /codon_start=1
                     /gene="nybE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 278.8; E-value: 5.8e-85)"
                     /gene_kind="biosynthetic-additional"
                     /note="phzD"
                     /product="isochorismatase"
                     /protein_id="AYV61406.1"
                     /transl_table=11
                     /translation="MSGIPDIPAYPMPGEQDLPANTARWTVRPERAVLLVHDMQRYFLR
                     PFADEQRRTLVGNVVLLRERCARLGVPVAFTAQPGSMTPEQRGLLRDFWGPGMRLDAAD
                     RDVVGELAPRPDDWLLTKWRYSAFFRSDLLARMRGAGRDQLVVCGVYAHIGVLATAVDA
                     FTHDIQTFMVADAVADFSADEHRLALTYAARRCAVVATTRGLPVEGGTLLGDVADGTAE
                     RRAAA"
     gene            complement(11337..12545)
                     /gene="nybF"
     CDS             complement(11337..12545)
                     /codon_start=1
                     /gene="nybF"
                     /note="3-deoxy-D-arabinoheptulosonate 7-phosphate synthase;
                     phospho-2-dehydro-3-deoxyheptonate aldolase"
                     /product="DAHP synthase"
                     /protein_id="AYV61407.1"
                     /transl_table=11
                     /translation="MLPIPLEKARQQPEWEDRAQVQRARETLAERPGLVRPDDVRTLRA
                     HLALVSEGAAQVVQAGDCAEDPAECTADHVARKVAVLDLLAGAMKLAGRRPVLRVGRIA
                     GQFAKPRSQPTERVGDGELPVYRGHLVNGPAPDAEERRPDPLRLVTGYMAAADIIAHLG
                     QGRATGIDQPVWTSHEALVLDYEVPLVRRTDEGELLLSSAHWPWLGERTRQVDGPHAAL
                     LAQVVNPVAVKVGPTVEVAELLALCALLDPERRPGRLTLIVRMGAGTVAERLPALVRAV
                     RSAGHPVVWLTDPMHGNTVVTRSGHKTRYVRTLQREVREFRAVLAGAGAFPGGVHLETT
                     PDQVTECVLDAWEADRVPEVYTSFCDPRLTVDQALEVLSAWGGAEPPAMAAEVAGPRQA
                     AGG"
     gene            12557..13396
                     /gene="nybG"
     CDS             12557..13396
                     /codon_start=1
                     /gene="nybG"
                     /product="hypothetical protein"
                     /protein_id="AYV61408.1"
                     /transl_table=11
                     /translation="MPAPAFARRPEPVTAVPRRRPASAVAWISIRKEYRGHGSTLMPRR
                     VRAKARRTGSSGQRKSVNCRDPAGRQTRWTRHGADVRRPFGPNRRPGPGFCAGGARAVE
                     SSATEPPGTRHAAGVRCSCRSSRDGAVRASPFAAGAGAGAGAGAGAGAVADPVRIRVRA
                     PAFMSDPRPRPCRARCPPGGVEASRGGPLAVDRRRLGGGPPAARWCAGARREGAPYRTS
                     VPAAGFEDVERGALRVRDPGAGAVRGVERSLAHGAAQLGDPGERGGQVLDAEGDVPV"
     gene            complement(13220..13993)
                     /gene="nybH"
     CDS             complement(13220..13993)
                     /codon_start=1
                     /gene="nybH"
                     /product="vicinal oxygen chelate protein"
                     /protein_id="AYV61409.1"
                     /transl_table=11
                     /translation="MTFRDSPWPEGTPCWVEVRVADPVRTSTFYGKLFGWTFFDHGPEY
                     DHYLTARLNDRAVADIGPRAPGQPAAGPSAWLVCFAVTSADATAARITEAGGTVPLAPC
                     DVGDHGRFAVAADPAGAEFAVWQAYAYPGAEVTGVPGAAVWHHCASRDAGASLAFYAAV
                     FGHTVTRAPGGCTTLGLDGRPVASVGEVPTGDGGAPSHWDVTFGVEHLATALTRITELG
                     GTVREGPFDTPHGPGARVTDAQGTPFDVLETGGGH"
     gene            complement(14004..14672)
                     /gene="nybI"
     CDS             complement(14004..14672)
                     /codon_start=1
                     /gene="nybI"
                     /product="NAD\(P\)H:dehydrogenase"
                     /protein_id="AYV61410.1"
                     /transl_table=11
                     /translation="MTTLTLLFHSRSGNTYQLVEKAAKTALDAGAEVRVRKVPELPDPM
                     ILDKGAYAELATATADVPDAGLDDLLWADAIMVGTPVHYGLPAPQILNFIDHTGPVAIP
                     GKLMNKAVSAFASGSMPHAGQQAAILALHNAFCHWGAVIVPNGSAAAVLHQPGNGAPYG
                     TGTISRHQANSVTEDNLGAIEYQTLRTLQVAGALGRGLRPEPGITMVSDERLRTFGLDI
                     "
     gene            14872..15279
                     /gene="nybJ"
     CDS             14872..15279
                     /codon_start=1
                     /gene="nybJ"
                     /product="hypothetical protein"
                     /protein_id="AYV61411.1"
                     /transl_table=11
                     /translation="MNDLANAVQHTAGLPVEPADLPTVFADAFNARNLELLDALFEPEA
                     VHVVRPGEVSAGEQRRAGLPAVVRDRIPITVTLRHVYVVGDTALLINDYVHDGVGPDGS
                     HVHTEGTATDIARRGPDGYWRYLVSNPSGTS"
     gene            complement(15461..16261)
                     /gene="nybK"
     CDS             complement(15461..16261)
                     /codon_start=1
                     /gene="nybK"
                     /note="arylamine N-acetyltransferase"
                     /product="N-acetyltransferase"
                     /protein_id="AYV61412.1"
                     /transl_table=11
                     /translation="MLDDTTVAAYLDRISARRPAKADLESLRNVQMRHLLSVPFENLGY
                     HLGEEIHMDERAVDKVVQERRGGGCYEVNPSLKFLLESLGYEVSLLPGRVWIKGRLTAP
                     LCHLALKVRAEGAEWLVDVGFGRNSRYPLSLATRDEQQDPHGSFRVAAADDGGIDVSLN
                     GTPQYRVYDIPCDIFDFGPTLWWYRTAPDSPFLQNLFCSLPTENGRVTLKEDQLTLIVG
                     TERESRRLSGEEEIREAYDKWFGIRLERLPVKASQDNGISMSFD"
     gene            complement(16263..17264)
                     /gene="nybL"
     CDS             complement(16263..17264)
                     /codon_start=1
                     /gene="nybL"
                     /product="amidohydrolase"
                     /protein_id="AYV61413.1"
                     /transl_table=11
                     /translation="MGTSKEAAAQPPWTGAIDVHHHVIPEFYAAELRDLGFASTLPGVD
                     KPRWEIGTSLSMMERQGIRAAVVNVWPGVPAVDAATGARLARRVNEFLAELTAAHPGRL
                     GAFAVLPLPHVDAALEELAYSMDVLGLDGVGLVTHYGGVYVGDPALDAFHAEAARRGTP
                     LFVHPTAPPVDQPAFGLPVSLCEFPFETVRLTAQLLYNRTLERHPGLRVILSHGGGGVA
                     YYAARLACGPLIRADLAERLPEDPVGYLRRLYSDTAMIGDPHAFPSVRAFTGAGRLLVG
                     SDFPFMPESFSAAGGRHIVGQGGFTPDELARIEFGNAAELFPRFAHERQEGR"
     gene            17565..18629
                     /gene="nybM"
     CDS             17565..18629
                     /codon_start=1
                     /gene="nybM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 334.3; E-value: 1.1e-101)"
                     /gene_kind="biosynthetic-additional"
                     /product="acetoacetyl-CoA synthase"
                     /protein_id="AYV61414.1"
                     /sec_met_domain="fabH (E-value: 3.2e-90, bitscore: 293.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPGAAPVHDAEAIGILGTGSCLPGKVVTNDEVGAPAGVTDEWIT
                     RKTAIRERRWAKADEATSDLAAMAARAALDDAGVCPADISLVVVATSTPDAPQPPTATA
                     VAAELGVPAGTPAFDINAVCSGFVFALTAAERMIRGTGGHAVVIGADIYSRTLDPTDRR
                     TVVLFGDGAGAVVLGPTATGGVLATELATFPQERDLIRVPAGGSRIPASRASVEEGLHY
                     FAMDGPAVRHFVENRVGPLIRSFLDRHLADRARRAHFVPHQANGRMIAALADSLGFLPE
                     HTHTTVRFLGNTGAASVPVTLDRAADRLVPGDLVVLAGFGGGMAAGLALVEWRTTRAGG
                     RGGKSRAALAADGT"
     gene            18685..19233
                     /gene="nybN"
     CDS             18685..19233
                     /NRPS_PKS="Domain: Polyketide_cyc2 (14-180). E-value:
                     7.6e-21. Score: 66.8. Matches aSDomain:
                     nrpspksdomains_nybN_Polyketide_cyc2.1"
                     /codon_start=1
                     /gene="nybN"
                     /note="polyketide cyclase / dehydrase and lipid transport"
                     /product="aromatase/cyclase"
                     /protein_id="AYV61415.1"
                     /transl_table=11
                     /translation="MNATEVPNEAEPLFDISVEVHVARSPECVYSVVSDLPRCHQWSEE
                     CTGGEWTHGTPGTVGAVFRGHNHRSADVVAWAPVVRGAWTTTAEVVAAEPPHRFSWAMR
                     TEAGRAQDSVWGYTLRPAPGGTSLTHHFRMGGPTEGITGITAGMSDDEKKAFFTEWGAK
                     VRSDMAATVERLKKVVESS"
     aSDomain        18727..19224
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nybN_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="7.60E-21"
                     /label="nybN_Polyketide_cyc2.1"
                     /locus_tag="nybN"
                     /protein_end="180"
                     /protein_start="14"
                     /score="66.8"
                     /tool="antismash"
                     /translation="DISVEVHVARSPECVYSVVSDLPRCHQWSEECTGGEWTHGTPGTV
                     GAVFRGHNHRSADVVAWAPVVRGAWTTTAEVVAAEPPHRFSWAMRTEAGRAQDSVWGYT
                     LRPAPGGTSLTHHFRMGGPTEGITGITAGMSDDEKKAFFTEWGAKVRSDMAATVERLKK
                     VVE"
     gene            19275..20927
                     /gene="nybO"
     CDS             19275..20927
                     /NRPS_PKS="Domain: AMP-binding (16-423). E-value: 1.9e-46.
                     Score: 150.3. Matches aSDomain:
                     nrpspksdomains_nybO_AMP-binding.1"
                     /codon_start=1
                     /gene="nybO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 159;
                     E-value: 2.4e-48)"
                     /gene_kind="biosynthetic-additional"
                     /product="long-chain acyl-CoA synthetase"
                     /protein_id="AYV61416.1"
                     /sec_met_domain="AMP-binding (E-value: 6.2e-42, bitscore:
                     134.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLQRIGNSGIRLGTLFDRAAARYPTNVLLLDHDLDIAPDRGRSL
                     TMTDVADLVSDFGSRLWRAGARPGDHLVIHKSNAFDITLLAVAAARIGAVPVLLSPHLD
                     GETVTALLRRVDRPYLLTDEAKLTGSLPKEVFPLCRRVLLASGSHRRATALAELAGAPR
                     IPALALPPEHPTLVTHTSGTTGLPKLAVHTAFSLEARYRPQALATALLRRREPVAIHVS
                     FVHSRLFTALALSLLRGFPVAVLADADPQRVAPLFARLRPAVLEAHPNTYLSWEQLASD
                     PRRPLANVKFFSSTFDALHPRTVSTLIGASRRRSAKFGQIYGQSEVGPSVARSYGKRRS
                     PTADGRCVGIPFPGMTGVRVVSRDGKRPTASSPGYIEVSSDGRIRTYLGEQERFEQQAS
                     ARWWRMGDLGYRTRWGCLHLLDREVDEIPGFGSTLSVEDRLFSRLAELTEVVIIETEDG
                     LPLPVVCTKDDRPLDEAAWRAAVADLPRMAPPVQWRQADLPQTATTKVKRLELARLVGA
                     GEEAGTRRAAAPAAGQPPVTVGPAEARSAGGEA"
     aSDomain        19323..20543
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_nybO_AMP-binding.1"
                     /evalue="1.90E-46"
                     /label="nybO_AMP-binding.1"
                     /locus_tag="nybO"
                     /protein_end="423"
                     /protein_start="16"
                     /score="150.3"
                     /tool="antismash"
                     /translation="FDRAAARYPTNVLLLDHDLDIAPDRGRSLTMTDVADLVSDFGSRL
                     WRAGARPGDHLVIHKSNAFDITLLAVAAARIGAVPVLLSPHLDGETVTALLRRVDRPYL
                     LTDEAKLTGSLPKEVFPLCRRVLLASGSHRRATALAELAGAPRIPALALPPEHPTLVTH
                     TSGTTGLPKLAVHTAFSLEARYRPQALATALLRRREPVAIHVSFVHSRLFTALALSLLR
                     GFPVAVLADADPQRVAPLFARLRPAVLEAHPNTYLSWEQLASDPRRPLANVKFFSSTFD
                     ALHPRTVSTLIGASRRRSAKFGQIYGQSEVGPSVARSYGKRRSPTADGRCVGIPFPGMT
                     GVRVVSRDGKRPTASSPGYIEVSSDGRIRTYLGEQERFEQQASARWWRMGDLGYRTRWG
                     CLHLLDRE"
     CDS_motif       19803..19850
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_nybO_0001"
                     /evalue="3.60E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="nybO"
                     /protein_end="192"
                     /protein_start="176"
                     /score="10.5"
                     /tool="antismash"
                     /translation="VTHTSGTTGLPKLAVH"
     gene            20924..22354
                     /gene="nybP"
     CDS             20924..22354
                     /codon_start=1
                     /gene="nybP"
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 289; E-value: 1.1e-87)"
                     /gene_kind="other"
                     /product="salicylate hydroxylase"
                     /protein_id="AYV61417.1"
                     /transl_table=11
                     /translation="MTTVAVAGGGIGGLATALGVSARGHRVVVCERAAEFAELGAGIQL
                     APNGMLALDRLGLAEAVGGIAVPVEELRFMDGVLGEHVVSMPLDARYRARFGNAYVVVH
                     RGELHRLLLRACRDSDRVELRASSPVTGYTHTDHGVRVRLGNGEVLTADALVGADGLHS
                     AVRAQLVGDGMPRNAGITVYRSIVPMERVPDDLRHRSVTWWAGPGRHFVHYPIAGGRLL
                     NLAPSVENEPAEVFSGVPVPGSRVREQFAQLCDTARRLLALGTEWKAWVLVDREPVGTW
                     TDGRVALLGDAAHPMLHYAAQGACMALEDAVVLGDLLDCSAHEFPARFRRYNAARRERT
                     ARVHRTARDSIGLWHARGETAAARNRTLAGMSADDLNDHLAWLHGAREFAAPDAVAPPD
                     AVAPTDVARPVPSPAAPAGARSGPGPLDGGTYTLGGYLAPTGGDAPRAAEPAPPPGTHT
                     LGGYLELPAPSRPHDGAA"
     gene            complement(22631..23761)
                     /gene="nybQ"
     CDS             complement(22631..23761)
                     /codon_start=1
                     /gene="nybQ"
                     /product="hypothetical protein"
                     /protein_id="AYV61418.1"
                     /transl_table=11
                     /translation="MHKGSQLAVFLETLHWSPERLAREINRRYGEGTVSLKAPYGWAKG
                     AYPRGQVPGFVAAILSDQLGRTIDISQIWPQRFPDAQPGGVGDPALGPPWTEEHVGRIL
                     RPLLDQEDGKREPWPAEPVPGAVLVSLAVDWLTAEGRLASARSQGAEVSTEMVDILTSR
                     IARLRRVSAAEDDSLVMNWVVHELRWALHMSENTAYDAPTGRRLYGAIAELAQLAGWLA
                     EDQGHYARGQHYLLAALRASGLAGDRNLGAYVLSCLSYHLTKCGNGQDALRLIKLADVG
                     MDDALPGVLHSLLASREARVYAHFTDGPAAEPAGQAGPTVHRVGSAGHPAGGPPERRDA
                     EGRLPGPGPRSPLIGAHSGVVTPSGHRGLSPCDCDR"
     gene            complement(23974..24690)
                     /gene="nybR"
     CDS             complement(23974..24690)
                     /codon_start=1
                     /gene="nybR"
                     /product="NAD-dependent epimerase"
                     /protein_id="AYV61419.1"
                     /transl_table=11
                     /translation="MFGANSSTGRHLTEQALGAGHTVTAVVRRPEAFPLSGPQLRVHAA
                     DVFDKAAVEEAVAGSEAVISILGVPYQRKPVTVLSRGITHITDAMAAHGVKRLVAVTSR
                     LLAVHAPRSEGEKPLYERFVYRRLLYPFLTTLGRTLYDDMLRMEHIVRATELDWTLVRP
                     SALYNTDVVSDYHFGPPESPGLYTSRIDLAHSLLHEVTENSHVRSVVSVFTTEGVPTFG
                     DVLKKEVMRIGSWEHK"
     gene            complement(24757..25518)
                     /gene="nybS"
     CDS             complement(24757..25518)
                     /codon_start=1
                     /gene="nybS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 64; E-value: 2.4e-19)"
                     /gene_kind="biosynthetic-additional"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="AYV61420.1"
                     /transl_table=11
                     /translation="MTKSVHHDRISEQYQASSTQYDNVKNLPYAFVERETLLSGVPDLT
                     GKRVLDVACGTGFYSRIFKRLGADKVVGVDIEQSMVDVARQIEAEAPLGITYDAVDAAE
                     LPVLGEFDVVAPIWAFVHAKDTAEYHDMVARCAANLVSGGTMVALCSNPDIDLDKMSVY
                     PRYGLSITPKEKHGDLQVIHIEMDVEPHVGFDGFFWPAGATEEAMEKAGLIDVKRHPNR
                     APGHVAGMSEKGYWADFVANPPFALYTAVKP"
     gene            complement(25626..26624)
                     /gene="nybT"
     CDS             complement(25626..26624)
                     /codon_start=1
                     /gene="nybT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /product="isopenicillin N synthase family oxygenase"
                     /protein_id="AYV61421.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 2.4e-23, bitscore:
                     73.5, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNAQPTVTVTDGFVPVIDLSSRKTPEGRAAIADAIGNALRSSGF
                     FIVVGHGVSRDLVDRMFTTTNAFFKLPEEEKDLVASRPGVSGYRRAGGTLARSLDQETP
                     PDLCETFAAHVTGELSDEERAGLGDQWASWTHRNVWPKNPEGFRGAWQDYMAAMEELAA
                     DLMRLFALALELDEDFFDDKFDHHGSSVAVNYYPPQHTPPLPGQLRRGPHTDFGSLTIL
                     YQEDDRGGLQVLQGEDTWRDVAAIPGSFVVNIGDLMALWTGGRWVSTMHRVVNPPHGDT
                     TSRLTIPFFYLPNHDASIEPMRPFTDSSAVERFDTVTVSEWVSRKVQKIFS"
     gene            complement(26908..27933)
                     /gene="nybU"
     CDS             complement(26908..27933)
                     /codon_start=1
                     /gene="nybU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /product="isopenicillin N synthase family oxygenase"
                     /protein_id="AYV61422.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 4.9e-24, bitscore:
                     75.7, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNAQLPPTAAEGFVPVIDLSAKDTAPGRAAIATAIDQACTSSGF
                     FVIVGHGVPEDLIGRMFTTTKAFFTLPDEEKDLVAHRPGVSGYRRTGGTTALSLDQETP
                     PDLCEAFSAHVTGELSDSERGRLGDQWATWTLANIWPERPAGFREVWQEYMAVISDLAA
                     DLMRLFALALDLKEDFFDDKFDHHGSSVAVNYYPPQHTPPLPGQWRRGPHTDFGSLTIL
                     YQEDDRGGLQVLQGEDTWRDVAAIPGSFVVNIGDLMALWTGGRWVSTMHRVVNPPHGDT
                     TSRLTIPFFYLPNHDATIEPLRPCPDAAGGPVGSRRTDLTSVIAGEWMSRKIQKMFAGT
                     P"
     gene            complement(27992..29476)
                     /gene="nybV"
     CDS             complement(27992..29476)
                     /codon_start=1
                     /gene="nybV"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 383.8; E-value:
                     1.5e-116)"
                     /gene_kind="transport"
                     /product="MFS transporter"
                     /protein_id="AYV61423.1"
                     /transl_table=11
                     /translation="MTDIKQEAPAPPAQSPKRWWALPVVSLAQLMVVLDATIVNIALPS
                     AQQDLGMSDADRHWVITAYALAFGGLLLVGGRVCGALGHRRSFTLSLIGFAVTSALGGA
                     ANSAGMLFAARAGQGVFAALLAPAALSLLILTFTDGRERGKAFGVFAGVGAGGAALGVV
                     AGGLLTEYTDWRWCLYINVPMAALALLGVPFIIRDRPSGTLRHLDLPGVLLSVAGLVCL
                     VYGFTQAEPHGWGDPKVLSLLIGGIVLLGLFVLVEARTGHPLLPLRILAHRTRGVAFVS
                     VCVMFIAMFGFYLFVSYYTQTILGYSPVKAGMTLLVNAVCTTIGAMLIAGKLTGRVPAN
                     VLIAGSLLSSALGMLILTQLEVDSSNVFLVYLTPAMILTGLGLGCLLAAATNMATVELG
                     HAEAGVASAAYNTVQQVGAAFGTALLNSIATSVTGDYLKEHGAGPESVNAGTVHGYTVA
                     LWVAFGILLAGAVAVALFSRRRDSEGRPEAVLESTH"
     gene            29762..30490
                     /gene="nybW"
     CDS             29762..30490
                     /codon_start=1
                     /gene="nybW"
                     /gene_functions="regulatory (smcogs) SMCOG1239:TetR family
                     transcriptional regulator (Score: 183.9; E-value: 6.4e-56)"
                     /gene_kind="regulatory"
                     /product="transcriptional regulator"
                     /protein_id="AYV61424.1"
                     /transl_table=11
                     /translation="MISEVNVIADKERTKSRSGGGVGNVWLRASREKQGEPPLTRARIV
                     DAAVALLDDEGMGRLTMRRLAERLQVGATTLYWHVATKDDVVDLAVDAIFGETQVPDRH
                     ADSPREDIATLVDGWRKAMLRHPWAATLPARQRPLMGPNFLAWMEFLQSALVRAGVTGK
                     RLHAATWALYNHVMGATAAQSSLQLSAEETRLGQEYLENRRERYPTVAANNYIADDDWD
                     ANFSLGLEFLLDGIEAGSRP"
ORIGIN
        1 tcaagtgcgc ccttccgctt cctggacggc ttccagtacc ggctcctggc tcatccagtc
       61 cgcgcgcagc accgggaagc ccgcgcgctc gtaggcgagg cacacctgcg cgtcgtcgtc
      121 caccaccagc aggacggggc gctcgcgggc gaggtgccgc agcagctccg gcttggcgac
      181 ccgcgcgggg cggcggtccc gctcggcgcg catgaggagc cggtcgccgg gcaggtcctg
      241 ctcgcggagc cacgccaggg tgtcggcgcg gcagcgttcg gggcgtccgg tgacgtaggc
      301 gagttccccc tcccgcgcct tctcgcgggc cagagcgacg ccctcggcca gcggcgggtc
      361 gtggacggcc gcggcgaaga aggcttccca gtcgcggggg cgccgctgga ggagcggcag
      421 ccggtgccgg acatcggcca gcgtcccgtc cagatcgaac accaccaccg gcgcggtcac
      481 cgcccccgct tccgccttcc ccttcgccac cgcccagctc cttcggcgtc cgacgctccc
      541 ccgcctgcct tctcatggaa acagacgagg gtgtgtaccg ggatgtccgg cggggcaccc
      601 gtggtgggcg cgtccgccgg cgtgcggagg gtccggcgag aggtttcggg aggtcttggt
      661 gacggagaac ctggggaatt acgcgccgac cgccggccac acgccggacg cggacctgac
      721 cgggtaccac gtcgaggcgc ccgacggccg cgccggcacg gtcgacgaga actccacgga
      781 gatcggttcc gggtacctgg tggtggacac cggcccgtgg atcttcggca agaaggtgct
      841 cctcccggcc ggcgcggtcc tgggcatcag caacgccgac cggaccgtcc gcgtcgccct
      901 gtccagggaa caggtcaagg cggcccccga gttcgacgag gacaggcacc tgggcgaccc
      961 gcgccaccgg gaccagctcg gcggccggca cagcaggggc cactgagacc gggaccctgc
     1021 ccggcccggc ccgcccccgg tcacagctcc cggtcccgga ccccgggtca cagctcccag
     1081 gccacggacc ccaggtcaca ggcgggaggt cgcacgcggg cctccggtca caggttcccg
     1141 gccgcacgcg cgcccccagt cacaggcagg cgcggcccca ccccctcgcc gccaagggat
     1201 cggcgtccgg ccgcagtccg gccagttcgg tggccgcatg ggcgaccgag gcgagcgtgg
     1261 cgtgccggtt ccaccccgcg tacgagcggc ccacgaagtc ccgtatcccc acgcgttcgg
     1321 ccagcggcac gccctgccgc tccacccggc ggctcagccc cacgagccgc agcagggcgg
     1381 agtggtcggc ccgcgccatg tccgtcagcc agagttcctc gggccaccgg gagcggccgc
     1441 cgcccacacc gatcagcagc aggtccccgt tcccggtgcc gcgttgcccg gaggcttccc
     1501 gtacggccgg gaggcgcacc cgtgccgtga cgaccagctc cggtgtgtcc ggggtgccgg
     1561 acgggatcag ggccacgcgg ttccggccgg ccctggccat ccgcgcgatg cggctcgcct
     1621 gcagggggct gtcgccccac cccggcagcg aggggtcgtt gggcagcagc caggtgtccg
     1681 gggcgatctt cgagacgtgc cggagccccg ccgcgccgag ccgggcgacc agtttgatgc
     1741 cgtccagccg ctcggcgttg agcaccaccg ggcgacgcgg cagcgacagg cgcgccgccg
     1801 tctccacgta ggcgttcacc atcgcctcct ccggtgtccg ccaggcggcc gggtccgtgc
     1861 ccggcaccgt cccgcggcag tcgtcggggg tgcctctcgg cgactgggag ggcaggtgca
     1921 gctgccagtt cagcgggtgc gcggtctgcg cggtcacgcc ccacacgccg gtcacctgct
     1981 gggcggtgac ggcctgcccc cgctcccagg agaaggtgcg ggtcacgccc gccgagtgcg
     2041 tgccggactt cgggatgagc agcggatgga ccacgtaggc gcgcggtggc agccgttgga
     2101 ggacatggcg tcccagggct tcccgcatgg ggtcccattc ccatgtcgag tcgttgatga
     2161 agtggtgcag gccctgatcg ttgacctggt cccccaggaa tgcggcgatg ttccgcaccg
     2221 atttccttcc ggtcgctccc agcagaccac gcaggtacat caatcctttt cggcgttggt
     2281 ccgcccgcgg gagcgaggcg aaaacgacgg gggagagttc cgccaccgaa cggtcgaggg
     2341 caggtcttcc ggtggtttcc gggccggggc cgtccgtcgg gtcgtccagt aatgcgatgc
     2401 agtcgggttc gcggttgacg agagtcatgc cgtgcctcct ggtgggtgcg cggtgcgttt
     2461 cccggaccgc gcacgggcgt gcgcggtcgt gatcgatgtg gtgagcggac aggtgcgagg
     2521 gcggatacgg gcctggggcc tgccggtggg ccctgcgggc aaggggccgc cggggccggc
     2581 cgcgaggtgt ccgtgccctg gtcccggtct ccggcgcggg acgaccggca cctgggcacg
     2641 tcgcgagtgc cgtgcgcggg cgcgtcggta cggcgcaccc ggtcgtgcgc gggcacgtcc
     2701 gccgggtccg cggaaggagg ctccggtgcg gcctggcgga gcgtgcggcg tcgtcggcgc
     2761 acgtcgtcgg cggtccggag cgcggtggtg ggtgggagtg gctgtcacat gtccggtacg
     2821 ggggtaccgg cttccgggcc tcggtccggc ccgtcagggg cggaggggag agcgggtccg
     2881 ggaggagagg gcccccgcgt gcgggtgcgc actgcgtggc gggccgagtc ggtcgcgtac
     2941 ggagcggaag cggcgtacgg agcggagggg caccgtgcgg gctgccggca cggcggggga
     3001 cgcgggaggc tcagtcacgc cctcgcggga aggcggggcg tggcgcgcgg cggtcgggac
     3061 ggacgcgcgg gcgcggcgcg gtcgctgggg cggtacggcg ccagggttcg gtcaattccc
     3121 gcggtgctcg gtacacgtac atttctcccc ctatttttcc ggccctgggt cgattggtcg
     3181 tcggaatgag ggggcgaata gctgcggtta ccatgtgtat aagaatccgc agcctgttct
     3241 tcccccgttc cctaaggctg cgaaaatcca aacccacggg cggtgtgcgg cgcaaggtcg
     3301 tcagcgggtc agctggtcat gagccgggtc agggtggtca gcgggacggc gggcagccga
     3361 tattcccgtg aacgcccccg agacagtcag gaatccgtgt gcggcgccgg ggaaagccac
     3421 ggattccgtg ggtgacggcg cgctccgctg atggggatgt ccggttccgc tgcgggcgga
     3481 tgcggcgggt ggccccgggg gactcgtggt ttcctaccag acggttcccc accgagcccc
     3541 tccggcgggg agccgccctc cggagcgggc ccgtgccggg gacgaccccg cccctcgcgt
     3601 ggactccgcc cggcctgccg gcccccctcg caccggagcg ggcaccacgg tgcgggacgg
     3661 gccggcggtg ggtcgtcgcg gtcagcagcg gtcgggaacg ggtcaggaac gggtcaggtg
     3721 cgggtcacgg cgggtcagaa gccggtggtg cggcggggcg cgcagggcgc cgtccgttcc
     3781 gtcggggacg aggcgggggc ggggtttcag ccgtctcctt ccgcgccgcc cggccgcagt
     3841 tcgcggtcca ccaggccggc cgcggcgccg gtgtagccgg ccggatcgca cagcgggtcc
     3901 agttcggcgg gggggatccg gccggccaac tcggccgcgc cggcgaggtg tacggccaag
     3961 gggcgcccgt cctccgccgc cgccgcggtg gcgcgggtca gcagggtgcg ggcggcggcc
     4021 ttgcccagca gcggtgccag cgcggccacg aggcgctcgg cgacgatccc gccctcggtg
     4081 agccggaggt tggcgcgcat ccgcgcgggc cgcacggtca gtcccccggc cagctccacc
     4141 gccgtgtggg cggcgccccc ggtcaggcgg aggcattcac gcagcggctg ccactccgcg
     4201 tgccaggcgc ccgcggaacg ctcgtcctcg gtgagcatgc actgggtcag cacccccgcg
     4261 agcgccggga cttgaagggc ggcgctgcgg accagcgtgg ccaggacggg gttgcgcttc
     4321 tgcggcatcg cggaggagct gccgcgtcct ggtacatggg gttcgacgac ctcgcccacc
     4381 tcggtacggg tgagggacag cacgtccacc gccagtttgc ccagcgcgcc cgcgccgtgt
     4441 gccaggacgg cggcgaggtc ggccatcggg gtgcgcaggg tgtgccaggg cagggcgggg
     4501 gcgcgcagcc cggtctcggc ggcgaacgcc gccacgaggc gctccgggtc cgcgccgtgc
     4561 tcgacgtatc cggcgagggt gcccgccgca ccgccgagcg agaccggcag ggcggccagg
     4621 acggtggccg cgcgggcgtc ggcgtccagc accgctcgcc gccagcccgc ggccttgagc
     4681 ccgaaggtgg tgggcacggc gtgcagcgcc agggtgcgtc ccggcagcac cgtgtcgcgg
     4741 tgtgcgcggg cgaggcgcgc gagcgcgtcc gcgatacggg ccaggtccgc gcgcagcagg
     4801 cgcagcgcgt cgcgggagac gagcatcgcc gccgtgtcga agatgtcctg gctggtcgag
     4861 ccccggtgca cgtactcggc ggcggccggg tccgcctccg cgaccgcgcg cgtcagggct
     4921 ccggccagag agaccacggg gttggcgctc tcgcgtgcgc ggacggccag ttcacgcgga
     4981 tcgaaccggc cggcccgcgc ggtcctcgtg atgacctcgg cggcgtgtgc cggtacgagg
     5041 ccgagcctcg cctgcgcgcg ggcgagcgcg gcctccgcgt cgagcatggc ctggagccac
     5101 gcggagtccg agacggcccg ctcgacgggg gtgcccgcgc ggaccgggga gagcaggccc
     5161 gcgtcgagga cgtggggcgc gggcgggggc ggcgcggtac cggccgtggc ggctctcgcg
     5221 ggcggtgtgc tcacagcagc acctcgccgt gcgggacccc ggccgccgtg gcaccggctg
     5281 ccgcgtcgct gggccccagg ccgagcacgg tgcgggcgat ggcgtcggcg tcggcgagcg
     5341 tcaccgagtc cacaccgggc cggatgccgg ccgccgtcac ccagtgcacc gcctcggtcg
     5401 gcaccccgta cgcgaagcgg cgcgggtgcg cccgcccccg ggcgtcgagc agccggtagg
     5461 gccgcggggt cacggccagt ccgcccgtct cgtacgtgcc gccgtccgcg gtggcgaccc
     5521 ggtagggggc gcacgcgtcg gtgtgccgca ggtgccgcag cagcgggtcg gccgtgcggc
     5581 gcagatccgg cgcgggcagg cgtgcctcga tgaggacccc ggcccggacg gtggggccgg
     5641 gcaccgtctc ggagtcggcc acgaacgccc ggcgacgggt gtcgatcctg atccgggtgc
     5701 cggggccggt cagctccagg acaccggccc tcaccagggc acgcatctcc tcgacgcgcc
     5761 ggggcggcgg gccgatggag aggaaggcgt tcaagggcgt gtaccaccgg tccagttcgt
     5821 cccggtgcga ggacccctcc aggccgccgt ggtccacggc gagccggatc tcgttccgca
     5881 ggtcgcgcag gacgtcgagg gcggccttga ccggtccgcc gacgttcccc tcgcgggcct
     5941 gccggacgtc ctccgccagc cggtcgagca gccaggcccg gaagtcgtcg cggtcggtga
     6001 acgtacgcgt gcgtgcgggg tccgcgaggg ccgcccagtc ccaccggtcg gcggcgggga
     6061 tccggtgggc gtccaccagg gcctcgcgcg cggccggttc ggcgcaggcc gcgtagcggg
     6121 cggcgaacag ctccgccgcc tcggcgccgc gccggtgcct gagccaggtc tcgtagtaga
     6181 cggtctccac ctcgcgggcg atcagcggcc acaggtcctg ggcgaaggac agcccggcgc
     6241 ccgcccgtgc ggcacgcgtg cgcagccggg ccacgtggtc ggccgtcagc aggcggggga
     6301 ggtggcggcc gtgcgcgccc ttctcgttct cgccgcgcgc gtggaacggc acaccccggc
     6361 gcgaactggc gtacaggagc ggctcctcgc cgctggggcg gtacaccagc tccccgccga
     6421 cgcggtcgaa gaggccgccg cggcccaggg tgaacagggc gaggtagtcg aagaagcaca
     6481 gcccgaggcc gcgcagcagc accggctccc cggcccggat gccgtcgagg cgggcgtccg
     6541 ccgggttggc cggcggcagg taggtcaggt ggttgatacg ggcgaggctc gcgatgcgct
     6601 cctcgtgcgg ggtcggccgg gtcggcagat gtccctgggc gagcacgacg gcgtccaggt
     6661 ggttgagccg ggtgccgttc tccagccgga cgccctgcgg cccgccggaa tacccgaggg
     6721 tgtcggccat ggccacggcc cgggacctgt gcaccctgat ctccacatgg gcgggggcgc
     6781 cctccacgac gcggcggagg cagtcggcga agtagcgccc gcacagcgcg cgcgtcgggt
     6841 aggagtcggg cccgagcgcg tgcgcctcgg cgagggtggc tgcgtcgtac gccgtgtcgg
     6901 gggtgctgcc ggccgcgtcg tcccccgctg ggggtgcggg cagggacgcg gcccactcgt
     6961 acaggctcgg tcccggctcg atgggaccgg cgatgcgcga ggcaacgtcg gtgaagacgg
     7021 tgatctgtga ggcgaccgtg ttcgccagca ggtgccgcga ctggccggtg cgccacaccg
     7081 atcccgcacc ggccggcgcg gagtcgacga gatggacgag cacccgcgaa cggaacggcc
     7141 gcgcccgttc gttcgcgcac agtctctcca gcacggcgag cccgcgcggg cccgcgccga
     7201 tgaccgcgat ctcgtgtgcc gtcgtgttca atccgagcac cccttctcat tccggccggg
     7261 gacatatggc agcgccggac ctgcccgaat acggcgagga cgtgcgaggg aacaccgcac
     7321 gcattctgaa agggcgggcg ggtgcccggc aacgccggcg ggagcaatca gtcaagtgcg
     7381 ggcggtgggg aaaaggaacg gtaaaaggcg gcccggcgat gcgagttgac acattccgca
     7441 cccgaccggg ccgccgcgtg tccggcgccg cgtcctctgg gagaatcccc gtatgcgtgc
     7501 tgcctacatc aacgaattcg gtccggcaca ttccatacgg ttcggtccgc tccccgaccc
     7561 ccggccgggc acgcacgagg tgctggtgga cgtcgaggcg accaccgcca accacgtgga
     7621 caccttcatc cggtccgggg cggtggagac gcccgtggac ttcccgttcg tggtcggccg
     7681 cgatctggtc ggccgggtcg ccgggacggg cgacggggtc accgggttcc gggtggggga
     7741 gcgggtgtgg tgcaacagcc tcggacacgc cggacggcag ggggcggcgg ccgaacgcgc
     7801 cgtcgtgccg gccgaacggc tctaccggct gcccgacggt gtcgcccctc agaccgcggt
     7861 gacggtggtg cacccggcgg ccaccgcgta cctgggcctg gtcacccacg gccggctgcg
     7921 ggcgggccag accgtggtcg tggtcggcgc ggcggggaac gtgggggccg ccatgctggt
     7981 cgtcgccgcc gcggcgggtg cccgggtggt ggcggtggcc cgggcccggg acgccgccta
     8041 ctgccgtgac ctgggagccg atgtggtggt ggaccgggag gcggacgggc tgggtgaccg
     8101 gctggcgcgc gcgtgcccgg aaggagtcga cgtctgggcg gacgcggccg gcgtcaacga
     8161 cctcaccacc gccgtgcggc tgctcgcccg gcgcggacgc gtcgtcctgc tcgccggact
     8221 gcacaccacg cccgtgctgc ccgccggacc gctgtacgtg cgggacgggt ccgtcgtcgg
     8281 cttcgccatc accggggcca cggccggcga gctggcgcag gcggccggct gcgtcaacag
     8341 gctgctggcc gggggccgtc tgcggccgcg cgaggtacgg gtccttccgc tgagcgccac
     8401 agccgaggtc caccgcatgc tggaggcggg cgaactgcac ggccgccggg tcgcgttgac
     8461 gacgggctga cggggccggt gcggtcgccg ccccggctcc gcgggcggta cggcggggca
     8521 gcgcgcggcc gcgcccgccc accgtcagga ccgcaccggc tgcccggcgc cgtcgagcac
     8581 accggccagc agcgtcccga ggatgcgcac cccgtcgtgg gtgaggaccg actcggcgtg
     8641 gaactgcact cccgcgaagt gccgtccccg cagcgcgtgc acctcaccgg tcgccgcgtc
     8701 ccggcagacc tcgaccgggc ccgtaccgta cggggtcagc agcccggacg ggctgtgcgc
     8761 cacgaagctg ttgtagaagc ccacccgctc cggccgcccg aacaggtcga tgtccttctg
     8821 caccccctgg tgcgggatgt ccctccggcg caccggcagg cccagccggt ggctgaggac
     8881 ctggtggctg aggcagacgg cgaggaacgg gcggcgcgcc tccagcagcg tgtccaccgc
     8941 ctcgtgcaga tgggcgatcc ggggctcacc gacctccagc gggctgcccg gacccggccc
     9001 catgacgacg aggtcgtgct cggcgaagga gtagggctcg tcgaaccgcc gcaccgtcac
     9061 ctccaacccc gcggagcgca gttggtgggc gatcatcgag gtgaaggtgt cctcggcgtc
     9121 gacgaccagc acccgccgcc cgtccagtgc ggaagggcgg ccggcggcgg ggccggaccc
     9181 gtccagccag aagcgggcga tctcctggtt gcgggcccgc agcgccgacc gcaccgaggg
     9241 gtgccggccc agcgggccct ccggctcggc gcgcagggcg gacagcagac cggtcgcctt
     9301 cgcgagcgtc tcggccacct cggccgccgg ttcggagtcc cgcaccaggg tggcgcccac
     9361 tccgatcgcc atccggccct cggaggtgat gtcggcggtg cggatgagga tggaggagtc
     9421 cagcgtgcgg cggccgcggc cgtccctgcc gatgagcgcc gccaccccgc tgtagtagcc
     9481 gcgcccagcg ggttcgtacc ggttgatcac ccggctcgcg ctctccaggg ggctgccggt
     9541 gacggtcggc gcgaacaggg tggcgctcag gatctcccgt acgtcccgct cggtgcgccc
     9601 ctcgatgacg tactcggtgt gggcgagccg tgccatctcc ttgaggtacg gccccaccac
     9661 gcgcacgtcc gcgtcgcaga accgggacat catcttcagc tcctcgtcca ccaccatgaa
     9721 cagctcgtag gtctccttgc ggtccgccag gaagtccatc accccgctga gggtggggcc
     9781 gtcaggcgga tagcggtagg tcccgctgat cgggttcatc accgcgaccc cgtccgcgag
     9841 gctcagatgc ctctccgggc tggccccgac gagcgtgcgg tcgccggtgt gcacgaggaa
     9901 cgtccagtag acgccggcct cccgcgccag cagccgccgg aagaaggcgg tcgccgtggc
     9961 cggggtgtag cccgtgagat cggccaggaa acggcgcttg acgacgaagt tcgcgccggc
    10021 gcccgcgccg atctcctcgg ccaggacgcg gcgcaccagc ccggcgtact cctcgtcgtc
    10081 gatgtcgaag cgctcgttct ccagccggat gggcacgtcc gggacggtgg cgagcacctc
    10141 ggcccggtcc agcgcggcct gctcccgtac ggtcatggcc agcagcggct ccccgtcgtc
    10201 cggtgcgggg aagccgcgct cggccagctg ccggtagggc accagcgcca gcacgtcggc
    10261 gccggccggg ccccgcgccg aggcggggac gggcaggtcg gcgatgcgct ccacgggccc
    10321 gaccggtccg gtgaggacct ccacccggtc ggacccggcc gccgtcgggc ggtgcagcag
    10381 ggcgaacggg ggaggggagg gggccagcac ccgctccagc agcacccgcg ccgggtcggc
    10441 ggccgtccgc cgggcgctca cgcggcggcc cgcctctccg ccgtcccgtc ggccacgtcg
    10501 cccagcagcg tgccgccttc gacgggcagt ccgcgggtgg tggccaccac ggcgcaccgg
    10561 cgcgccgcgt aggtgagcgc gagccggtgc tcgtccgcgg agaagtcggc gacggcgtcg
    10621 gccaccatga acgtctggat gtcgtgggtg aaggcgtcca cggcggtggc cagcaccccg
    10681 atgtgggcgt agacgccgca gacgacgagc tggtcgcggc ccgccccccg catccgggcc
    10741 agcagatcgg accggaagaa ggcgctgtag cgccacttgg tgaggagcca gtcgtccggg
    10801 cgcggggcca gctcccccac gacgtcccgg tccgccgcgt cgaggcgcat ccccggcccc
    10861 cagaagtccc gcagcagacc gcgctgttcg ggggtcatgc tgccgggctg cgccgtgaag
    10921 gcgacgggga caccgagccg cgcgcaccgc tcgcgcagca ggacgacatt gcccacgagc
    10981 gtgcggcgct gctcgtcggc gaacgggcgc aggaagtagc gctgcatgtc gtgcaccagc
    11041 aggacggccc gctcgggacg caccgtccag cgtgcggtgt tcgccggcag atcctgctca
    11101 ccgggcatcg ggtacgcggg gatgtcgggt atcccggaca tggcggttcc tctccgttcc
    11161 tctgggtgcc gctgcgtgcg cgcccggacg ccgctcacgt gccgagcccg tgtgccgagc
    11221 gctccgggcc caccgggtgg accggacttc ccggctgtcg atttcgctgt cgctgtcgtc
    11281 gctgtcgccg cgcgtggccg cccggggggg ctgtcggcgc cgctgcctgc catgtctcag
    11341 ccccccgccg cctgccgcgg cccggccacc tcggccgcca tcgccggcgg ttcggccccg
    11401 ccccaggcgc tcaggacctc gagcgcctgg tcgacggtga gccgcgggtc gcagaagctc
    11461 gtgtagacct ccgggacccg gtcggcctcc caggcgtcga gcacgcactc ggtgacctgg
    11521 tcgggcgtcg tctccaggtg cacaccgccg gggaacgcac cggccccggc cagcacggcg
    11581 cggaactcgc ggacctcgcg ctgcaacgtg cggacgtacc gcgtcttgtg gccgctgcgg
    11641 gtgaccaccg tgttgccgtg catcggatcg gtcagccaca ccaccggatg cccggccgac
    11701 cgcaccgcgc ggaccagcgc gggcagccgc tcggccaccg tcccggcgcc catccgcacg
    11761 atcagcgtca gccggcccgg gcgccgctcc gggtccagca gggcgcacag cgccagcagc
    11821 tcggccacct ccaccgtggg ccccaccttg acggcgacag ggttgaccac ctgggcgagc
    11881 agcgccgcgt gcggcccgtc cacctggcgg gtgcgctccc cgagccaggg ccagtgggcc
    11941 gaggagagca gcagctcccc ctcgtcggtc cggcgcacca gggggacctc gtagtcgagg
    12001 accagcgcct cgtggctggt ccacaccggc tggtcgatgc cggtggcacg gccctgtccg
    12061 aggtgggcga tgatgtcggc ggcggccatg tacccggtga ccagacgcag cgggtcgggg
    12121 cgcctctcct ccgcgtccgg cgccggtccg ttgaccaggt ggccccggta gacggggagt
    12181 tcgccgtccc cgacacgctc ggtcggctgc gaccgcggct tggcgaactg tcccgcgatc
    12241 cggcccaccc gcagcaccgg acgccgcccg gccagcttca tcgcaccggc gagcaggtcg
    12301 agcacggcca ccttgcgcgc gacgtggtcc gccgtgcact cggccgggtc ctccgcgcag
    12361 tcaccggcct gcacgacctg ggccgcgccc tcgctgacga gggccagatg ggcacgcagc
    12421 gtccgcacgt cgtccggccg gacgagtccg gggcgctcgg ccagggtctc ccgcgcgcgc
    12481 tgcacctgcg cccggtcctc ccattccggc tgttgccgcg ccttttccaa gggaatgggg
    12541 agcatgtcgc tagtcaatgc cggctccagc tttcgcacgg cgacccgagc cggtcacggc
    12601 tgttccgcgc cgtcgcccgg catcggccgt cgcctggata tcgatccgaa aggaatatcg
    12661 gggacacggc tccaccctga tgcctcggcg ggtgcgggcc aaggcgcgac gaaccggttc
    12721 gtcaggtcag cggaaatctg tcaattgccg ggacccggcc ggccgtcaga cccggtggac
    12781 ccggcacggg gcggatgtcc gacgtccttt cgggcccaac cgccgcccgg gccccggatt
    12841 ttgtgcgggc ggcgcccgcg cggtggagtc ctcggcaacg gaaccgccgg gaacgcgtca
    12901 tgccgcgggc gtccgctgtt catgccggag ttcccgcgac ggtgccgtgc gggcgtcacc
    12961 cttcgcagcg ggtgcgggtg cgggtgcggg tgcgggtgcg ggtgcgggtg cggttgcgga
    13021 tccggtccgg atccgggtgc gggcgccggc gttcatgtcg gatccgcgcc cgcgcccgtg
    13081 tcgcgcccgc tgccccccag gtggcgtgga ggcgtcaagg ggcggccctc tcgcagtgga
    13141 ccggcggcgg ctcggcggtg gtccgccggc ggcccggtgg tgtgccgggg cgcggcggga
    13201 gggcgccccc taccgaacct cagtgcccgc cgccggtttc gaggacgtcg aacggggtgc
    13261 cctgcgcgtc cgtgacccgg gcgccggggc cgtgcggggt gtcgaacggt ccctcgcgca
    13321 cggtgccgcc cagctcggtg atccgggtga gcgcggtggc caggtgctcg acgccgaagg
    13381 tgacgtccca gtgtgagggt gcgccgccgt ccccggtcgg gacctcgccg acgctcgcca
    13441 ccgggcgccc gtcgaggccg agcgtggtgc agccgccggg cgcccgggtc acggtgtggc
    13501 cgaacacggc cgcgtagaag gccagcgacg ccccggcgtc ccggctcgcg cagtggtgcc
    13561 acacggccgc accgggcacg ccggtgacct ccgcgccggg gtacgcgtac gcctgccaga
    13621 cggcgaactc ggccccggcg ggatcggccg ccaccgcgaa cctgccgtgg tcgccgacgt
    13681 cgcacggcgc cagcggcacg gtgccgcccg cctcggtgat ccgcgccgcg gtcgcgtccg
    13741 cactggtgac ggcgaagcag acgagccacg ccgagggccc ggccgccggc tgccccggcg
    13801 cccgcgggcc gatgtcggcg acggcgcggt cgttcagccg cgccgtcaga tagtggtcgt
    13861 actcggggcc gtggtcgaag aacgtccagc cgaagagctt gccgtagaag gtgctggtgc
    13921 gcacggggtc ggccacccgc acctccaccc agcagggcgt cccctcgggc cacggggagt
    13981 cacggaacgt catgcccgcc ccgtcagatg tccaggccga aggtgcgcag ccgctcgtcg
    14041 ctcaccatgg tgatccccgg ctccggccgc agcccccggc cgagcgcgcc ggcgacctgg
    14101 agggtgcgca gcgtctggta ctcgatggca cccaggttgt cctcggtcac gctgttcgcc
    14161 tggtgccgcg agatggtgcc ggtgccgtac ggggccccgt tcccgggctg gtgcagcacc
    14221 gcggcggccg agccgttcgg cacgatcacg gcgccccagt ggcagaaggc gttgtgcagg
    14281 gcgaggatgg ccgcctgctg gcccgcgtgc ggcatggaac cggaggcgaa cgcggacacc
    14341 gccttgttca tcagcttgcc ggggatggcg accgggccgg tgtggtcgat gaagttgagt
    14401 atctgcgggg cgggcagccc gtagtggacc ggcgtaccta ccatgatcgc gtcggcccac
    14461 agcaggtcgt ccagtccagc gtccgggacg tccgcggtgg cggtcgccag ctccgcgtag
    14521 gcacccttgt ccaggatcat cgggtcgggc agctcgggca ccttgcggac ccgcacctcg
    14581 gcacccgcgt ccagcgccgt tttcgcggcc ttctccacga gctggtaggt gtttccgctg
    14641 cgggaatgga agagcagagt gagcgtggtc aagggaaact ccttgtcgac cgattcgggc
    14701 gtaccggcac gcggatgacg gctgcatcat gccgttcgcg cgaaagccgg agccacggct
    14761 gattccgtca tctgtcaggt ccgcacggaa tactccgtcc ggaggcgcgg agctgacaga
    14821 gaccggcgct accccgtgcc ctcgggtttt cccggctgct gtactcggcg catgaatgac
    14881 ctcgcgaatg ccgttcagca cactgcggga cttcccgtcg agccggccga cctgcccacc
    14941 gtcttcgccg acgccttcaa cgcgcggaac ctcgaactcc tcgacgcgct cttcgaaccg
    15001 gaagccgtcc atgtggtgcg gcccggtgag gtgtcggcgg gcgagcagcg ccgcgccggg
    15061 ctcccggcgg tggtgcgcga ccgcatcccg atcaccgtca cgctgcgcca cgtctatgtg
    15121 gtgggggaca cggcactgct gatcaacgac tacgtgcacg acggcgtggg gccggacggc
    15181 agccacgtgc acaccgaggg cacggcgacc gacatcgccc gccggggccc ggacgggtac
    15241 tggcgctacc tggtctccaa cccctccggc acctcctgac tccggcacct tgcgacctac
    15301 cgtcccgggt ccgggaccca ggcccgggga cgccgaaggc cgacgaagcg ctccaccccc
    15361 ggaacggctc cgggggtgga gcgctcgcgg cctccggccg cggggaagga cgaccggagg
    15421 ccatggccgg acgccgtggc cgcgccgggc gcgcccgctg tcagtcgaac gacatggaga
    15481 tgccgttgtc ctgggacgcc ttcaccggca gccgctccag ccggatgccg aaccacttgt
    15541 cgtacgcctc acggatctcc tcctcgccgg acagccgccg gctctcccgc tcggtgccga
    15601 cgatgagcgt gagctggtcc tccttcaggg tgacccggcc gttctcggtg ggcagcgagc
    15661 agaagaggtt ctgcaggaag ggggagtcgg gcgcggtgcg gtaccaccac agcgtgggcc
    15721 cgaagtcaaa gatgtcgcac gggatgtcgt acacccggta ctgcggcgtg ccgttcaagg
    15781 agacgtcgat accgccgtcg tcggccgccg ccacccggaa gctgccgtgc gggtcctgct
    15841 gctcgtcccg cgtggccagc gagagggggt agcggctgtt gcggccgaag cccacgtcga
    15901 ccagccactc cgcgccctcc gcccgcacct tgagcgcgag atggcacagg ggggcggtca
    15961 gccgtccttt gatccacacc ctgcccggca gcagggagac ctcgtacccc aggctctcca
    16021 gcaggaactt gagcgaggga ttgacctcgt agcagccacc gccccggcgc tcctggacga
    16081 ccttgtcgac ggcccgctcg tccatgtgga tctcttcacc gaggtgatag cccagattct
    16141 cgaagggcac ggagagcaga tgacgcatct gcacgttccg cagcgactcc aggtcggctt
    16201 tcgccgggcg ccgcgccgaa atacggtcca gatacgcggc gaccgtggtg tcgtccagca
    16261 tgctaacggc cctcctgcct ctcgtgggcg aatcgtggga agagctcggc ggcattgccg
    16321 aactcgatgc gcgccagttc gtccggggtg aatccgccct gcccgacgat gtgacggccg
    16381 ccggccgcgc tgaaggactc cggcatgaac gggaagtccg agccgaccag gagccggccg
    16441 gctccggtga acgcccgcac cgacggaaag gcgtgcggat caccgatcat ggcggtgtcg
    16501 ctgtagaggc gccgcagata gccgaccggg tcctcgggca gccgctcggc cagatcggcg
    16561 cggatcagcg ggccgcaggc cagccgtgcg gcgtagtagg ccacaccgcc gcccccgtgg
    16621 gacaggatca cgcgcagccc cggatgcctc tccagcgtgc ggttgtacag cagctgcgcc
    16681 gtcagccgca cggtctcgaa cgggaactcg cacagcgaga cgggcagtcc gaacgcgggc
    16741 tggtcgacgg gcggcgccgt cgggtggacg aacagcgggg tgccccggcg cgccgcctcg
    16801 gcgtggaacg cgtccagcgc cggatccccc acgtacacac cgccgtagtg ggtgaccagg
    16861 ccgaccccgt ccaggccgag gacgtccatg ctgtaggcga gttcctccag cgcggcgtcc
    16921 acgtgcggca gcggcagcac cgcgaacgcg ccgagccggc cggggtgcgc ggccgtcagc
    16981 tccgcgagga actcgttgac ccggcgggcc agccgcgcgc ccgtcgccgc gtccacggcg
    17041 ggcaccccgg gccagacgtt gacgaccgcc gcccggatgc cctgccgctc catcatcgac
    17101 agactcgtcc cgatctccca ccggggtttg tcgacaccgg gcagtgtgga ggcgaatccg
    17161 aggtccctca gttccgcagc gtagaattcc ggaatgacat ggtggtgcac gtcgatggca
    17221 ccggtccaag gcggctgtgc cgccgcctcc ttgcttgtcc ccatgaaaat cccttgttcg
    17281 gacggccacc gcctcggcgc cccacgctag gaccgcttgc gggagaaggt cgatgtacgg
    17341 gccgggaagt ctgtcaactt ctgccgcacc ccgaggcgtt cacttccggt cgccgcggga
    17401 ttggcgcaac ggccaccgcc gccgacggag ctgacacttg ttgccgcgtt ttcctagggc
    17461 gccgcccggc ccccgaatac cgtccggggc aaaccttcgt accggacgcc gccccgcact
    17521 cccgcccggg aatgccgcgc ggcgacgagc tgaaatgagt catcatggcc cctggagcag
    17581 caccggtcca tgacgccgaa gcgatcggaa ttctcggcac cggttcctgt cttcccggaa
    17641 aggtcgtcac caacgacgag gtcggcgcac cggccggcgt gacggacgag tggatcaccc
    17701 ggaagaccgc catccgcgaa cgccgctggg cgaaggcgga cgaggccacc tccgacctgg
    17761 cggcgatggc cgcgcgcgcc gcgctcgacg acgcgggggt ctgcccggcg gacatctccc
    17821 tcgtcgtggt ggcgacctcc acacccgacg cgccccagcc gcccaccgcc accgcggtcg
    17881 ccgccgaact cggcgtcccg gccggcaccc cggcgttcga catcaacgcg gtgtgcagcg
    17941 gcttcgtctt cgcgctgacc gcggcggagc gcatgatccg cggcacgggc ggccacgccg
    18001 tcgtcatcgg cgccgacatc tactcgcgca ctctcgaccc caccgaccgc aggaccgtcg
    18061 tgctcttcgg cgacggcgcc ggagccgtgg tgctggggcc caccgcgacc ggaggtgtcc
    18121 tcgccaccga gctggccacc ttcccgcagg aacgggacct gatccgggtc cccgcgggcg
    18181 gctcccggat acccgcgtcc cgggcctcgg tcgaggaggg cctccactac ttcgccatgg
    18241 acggcccggc ggtccgccac ttcgtggaga accgggtcgg gccgctgatc cgctccttcc
    18301 tcgaccgcca tctggcggac cgcgcccggc gcgcgcactt cgtcccccac caggccaacg
    18361 ggcggatgat cgccgcgctc gccgacagcc tcggcttttt gccggagcac acgcatacga
    18421 cggtgcggtt cctcggcaac accggtgccg cgtcggtgcc ggtcaccctc gaccgggccg
    18481 ccgaccggct cgtgcccggc gacctggtgg tgctcgccgg gttcggcggc ggcatggccg
    18541 cgggcctggc cctggtcgaa tggcggacga cgcgggccgg cgggcgcggc ggaaagagcc
    18601 gtgccgccct cgcggccgac gggacctgac gaacccggac cgcgttttct tgccgccctt
    18661 cccacccccg gacaggattt cgccatgaac gccacagaag ttccgaacga agcagaaccc
    18721 ctcttcgaca tcagcgtcga ggtgcatgtc gcccggtccc cggaatgcgt ctattccgtg
    18781 gtgagcgatc tgccgcgctg tcaccagtgg agcgaggagt gcaccggcgg ggagtggaca
    18841 cacggcaccc ccggcaccgt gggcgcggtg ttccgcggcc acaaccaccg cagcgccgac
    18901 gtggtggcct gggcccccgt ggtacgcggc gcgtggacca cgacggccga ggtcgtggcg
    18961 gccgaacccc ctcaccgctt ctcctgggcg atgcgcaccg aggccggccg cgcccaggac
    19021 agcgtctggg gatacacgct gcggcccgca ccgggcggca cctcgctcac ccaccacttc
    19081 cggatgggcg gacccaccga gggcatcacg ggcatcacgg ccggaatgag cgacgacgag
    19141 aagaaggcgt tcttcaccga gtggggggcc aaggtgagat ccgatatggc cgccactgtc
    19201 gaacgcctca agaaagtcgt cgagtcgtcc tgaccccctg accttcatca gcagacccgc
    19261 atcgaggttg acgcatgctt ctccagcgca taggaaacag cggcattcgg ctgggcacgt
    19321 tgttcgaccg ggcggcggcc cgctatccga cgaacgtcct gctcctcgac cacgatctgg
    19381 acatcgcgcc ggaccggggg agaagcctga cgatgaccga cgtcgccgat ctcgtgagcg
    19441 acttcggctc gcgcctgtgg cgcgccgggg cacgccccgg cgaccatctg gtgattcaca
    19501 agagcaacgc cttcgacatc accctgctcg cggtcgcggc cgcgcggatc ggcgccgttc
    19561 cggtgctcct gtcgccccat ctggacggtg agacggtcac cgcgctgctg cgccgggtcg
    19621 accgcccgta cctgctcacc gacgaggcga agctgaccgg ctccctgccc aaggaggtct
    19681 tcccgctctg ccgtcgcgtc ctgctggcct ccggcagcca ccggcgggcc accgcgctgg
    19741 ccgagctggc gggggcgccg cgcatccccg cgctggcgct gccgccggag cacccgaccc
    19801 tggtcaccca cacctccggc accaccggcc tgcccaagct ggccgtccac accgccttca
    19861 gcctggaggc ccgctaccgg ccgcaggcgc tggcgacagc gctgctgcgg cggcgcgagc
    19921 cggtggccat ccacgtctcc ttcgtgcact cgcggctgtt caccgcgctg gccctctcgc
    19981 tgctgcgcgg cttccccgtc gcggtgctcg cggacgccga cccgcagcgg gtcgccccgc
    20041 tcttcgcgcg gctgcggccc gcggtcctgg aggcccaccc gaacacgtac ctgagctggg
    20101 agcaactggc ctccgacccg cgccggccgc tggccaacgt gaagttcttc agcagcacgt
    20161 tcgacgctct gcacccccgc acggtgagca ccctgatcgg ggcctcccgg cgccggtcgg
    20221 ccaagttcgg ccagatctac gggcagagcg aggtcggccc gagcgtcgcc cgctcctacg
    20281 gcaagcgccg ctcgcccacg gcggacggcc gctgcgtggg catccccttc cccggtatga
    20341 cgggggtgcg ggtggtgagc cgggacggca agcggcccac ggcctcctcg cccggataca
    20401 tcgaggtcag cagcgacggc cggatccgca cctacctcgg tgaacaggag cggttcgagc
    20461 agcaggcctc cgcgcgctgg tggcggatgg gggatctggg ctaccgcacg cgctgggggt
    20521 gtctgcatct gctcgaccgg gaggtcgacg agatccccgg gttcggcagc accctctcgg
    20581 tggaggaccg gctcttctcc cgcctcgccg agctgaccga ggtcgtgatc atcgagacgg
    20641 aggacgggct cccgctgccg gtcgtctgca ccaaggacga ccgtcccctg gacgaggcgg
    20701 cctggcgggc ggcggtggcc gatctgccgc ggatggcccc gccggtccag tggcggcagg
    20761 cggaccttcc gcagaccgcc accaccaagg tcaagcggct ggaactggcc cgtctcgtgg
    20821 gggcgggaga ggaagcgggc acacggcggg ccgcagcgcc ggcggccggg cagccgcccg
    20881 tcaccgtcgg ccccgccgag gcgcggtcgg ccgggggaga ggcatgacga cggtggccgt
    20941 cgccgggggc ggcatcggtg gactcgccac ggcgctcggc gtttccgccc gaggacaccg
    21001 ggtcgtggtg tgcgagcgcg cggccgagtt cgcggagctg ggcgcgggca tccagctcgc
    21061 accgaacggc atgctcgcac tcgaccggct gggcctggcg gaggccgtcg gcggcatcgc
    21121 cgtaccggtg gaggaactgc ggttcatgga cggcgtcttg ggagagcacg tcgtcagcat
    21181 gccgctcgac gcccggtacc gcgcccgctt cggcaacgcc tacgtcgtgg tgcaccgtgg
    21241 cgagctgcac cggctgctgc tgcgggcgtg ccgggacagc gaccgcgtcg agttgcgcgc
    21301 gtcctctccc gtcaccggct acacccacac cgaccacggt gtgcgggtgc ggctggggaa
    21361 cggggaggtg ctgacggcgg acgccctggt gggggccgac ggcctgcact ccgccgtccg
    21421 cgcacagctc gtcggggacg gcatgccgcg caacgcgggc atcaccgtct accgctcgat
    21481 cgtgccgatg gagcgggtac ccgacgacct gcgccaccgg tccgtcacct ggtgggcagg
    21541 gccgggcagg cacttcgtgc actatccgat cgccggcggc cgactgctca acctggcacc
    21601 cagcgtggag aacgagccgg ccgaggtgtt ctccggggtg ccggtgcccg gctcccgggt
    21661 gcgggagcag ttcgcccagt tgtgcgacac cgcgcggcgg ctgctcgccc tgggcacgga
    21721 gtggaaggcc tgggtgctgg tcgaccgcga acccgtcggg acctggaccg acggccgggt
    21781 cgccctgctc ggggacgcgg cccacccgat gctgcactac gcggcgcagg gcgcctgcat
    21841 ggcgctggag gacgcggtgg tgctcggcga cctgctcgac tgctccgcac acgagttccc
    21901 cgcccggttc cgccgttaca acgcggcccg ccgcgagcgc accgcccgcg tgcaccgtac
    21961 ggcccgcgac agcatcggac tgtggcacgc ccgcggcgag acggcggcgg cccgcaacag
    22021 gacgctggcg gggatgagcg ccgacgacct caacgaccac ctcgcatggc tgcacggggc
    22081 ccgcgaattc gccgccccgg acgccgtcgc accccccgac gccgtggccc cgaccgacgt
    22141 cgcgcgccct gtcccgtctc ccgccgcccc ggccggtgcc cggtccggtc ccggcccgct
    22201 ggacgggggc acctacacgc tgggcggcta tctcgccccc acgggcgggg acgctccccg
    22261 cgccgccgag cccgcaccgc cgcccggcac gcacaccctg ggcggctacc tcgagctgcc
    22321 cgccccctcg cggcctcacg acggggcggc ctgagatcgg gggaggggag gcaggcaggg
    22381 gagggcacgg gtgcggaggg gaggggagcc ggtcgccggg gacggcaccg gctcccccgc
    22441 cgggacggcc ggccgcgccg cgccgtgccc tgccctgcct gggatgttcc gggtggcctg
    22501 acccggcggt accccggccg tgccccgaac atgccccagc cacgtcccgg ttacgttccg
    22561 gccacgcccc tcccgtgtcc tggtcagggc acgggccgtg acgctccggc cggtgccggc
    22621 cgggcggcgc tcaccggtcg cagtcgcacg ggctcagccc gcggtggccc gacggggtga
    22681 ccacccccga gtgcgcgccg atcagggggg agcggggccc cggtccgggc agtctgccct
    22741 ccgcgtcacg gcgctccgga ggcccgccgg cggggtgtcc cgccgaaccg acgcggtgga
    22801 ccgtcggccc cgcctggccc gccggctcgg ccgccggtcc gtccgtgaag tgcgcgtaca
    22861 cccgtgcctc gcgtgaggcc agcagcgagt gcagtacgcc gggcagcgcg tcgtccatgc
    22921 cgacgtccgc gagtttgatg agccgcagcg cgtcctggcc gttgccgcac ttggtgaggt
    22981 ggtagctgag acaggagagg acgtacgcgc ccaggttgcg gtcgcccgcc aggccggagg
    23041 cgcggagcgc ggccagtaga tagtgctggc cgcgggcgta gtggccctgg tcctcggcca
    23101 gccagccggc gagctgcgcc agttcggcga tggcgccgta cagccgtctg ccggtcgggg
    23161 cgtcataggc ggtgttctcg gacatgtgca gtgcccagcg cagctcgtgc accacccagt
    23221 tcatgaccag ggagtcgtcc tccgcggcgc tcacccggcg cagtcgcgca atccgactgg
    23281 tcagtatgtc gaccatctcg gtggacactt cggcgccctg tgaccgcgcc gacgccagcc
    23341 ggccctcggc cgtcagccag tccacggcga gcgagacgag cacggcgccg ggcaccggtt
    23401 cggccggcca cggctcccgc ttaccgtcct cctggtccag cagcggccgc aggatgcggc
    23461 cgacgtgctc ctccgtccac ggggggccga gggccgggtc gccgacaccg cccggctggg
    23521 cgtccggaaa gcgttgcggc catatctggc tgatatcgat cgttctgccc agttgatccg
    23581 agaggatggc ggccacgaag cccggcacct ggccccgggg gtaggctccc ttcgcccagc
    23641 cgtacggagc cttgaggctg acggtgccct cgccgtatcg cctgttgatt tcccgcgcca
    23701 gtcgctcggg cgaccagtgc agggtttcga ggaatactgc gagctgcgat cctttgtgca
    23761 ccggtgcatc tcccccctgg aagttctccc ggattcacgg tcggatggtg ccgcttggtc
    23821 catgccacag gtctgttcca gtcttaccac gctgctttgg agttgggtac ggaatgagcc
    23881 ggtgtgcggt ccgggaaacg cggggaaaac gcgcatgggg acgacaccac cccgttccgg
    23941 ggcggtgtcg tcggtccgtg cgcggcttga atcctactta tgctcccagg agccgatgcg
    24001 catgacttcc tttttcagta cgtcaccgaa ggtcggcacc ccttccgtgg tgaatacaga
    24061 gaccaccgag cgcacatggg agttctcggt gacctcgtgt agcagggaat gggcgaggtc
    24121 gatgcgcgag gtgtacaggc ccggcgactc cggcgggccg aagtggtagt cgctgaccac
    24181 gtcggtgttg tagagcgcgg agggccgcac cagggtccag tccagctcgg tcgcgcgcac
    24241 gatgtgctcc atgcggagca tgtcgtcgta cagggtccgg ccgagggtgg tgaggaaggg
    24301 gtagaggagc ctgcggtaga cgaacctctc gtacagcggc ttctcgccct ccgagcgggg
    24361 ggcgtgcacg gccagcaggc gcgaggtcac cgcgaccagc cgcttgacgc cgtgcgccgc
    24421 catcgcgtcg gtgatgtgcg tgatgccgcg ggagagcacc gtcaccggct tgcgctggta
    24481 ggggacgccg aggatcgaga tgaccgcctc gctgccggcc accgcctcct cgaccgccgc
    24541 cttgtcgaac acgtcagcgg cgtgcacccg cagctgcggg ccggacagcg ggaacgcctc
    24601 gggccgtcgc acgaccgcgg tcaccgtgtg tcccgcaccc agcgcctgct cggtgaggtg
    24661 acgtccggtg gaactgtttg ctccgaacac agcgagcttc aatgcgattc tccgtctcga
    24721 gagggtgcca ctcgtccggt ctcccgaacc ggatcctcag ggcttgaccg ccgtgtagag
    24781 agcgaacggc gggttggcca cgaaatcggc ccagtagccc ttctccgaca ttcctgcgac
    24841 gtgtcccgga gcgcgattcg ggtggcgctt cacatcgatc agcccggcct tttccatcgc
    24901 ctcctccgtg gcgcccgccg gccagaagaa gccgtcgaat ccgacatgcg gctcgacatc
    24961 catctcgatg tggatgacct ggagatcgcc gtgcttctcc ttcggggtga tggagaggcc
    25021 gtagcggggg tagacggaca tcttgtccag gtcgatgtcc gggttggagc agagtgcgac
    25081 catggtgccg ccgctcacca ggttcgccgc gcaccgggcc accatgtcgt ggtattcggc
    25141 ggtgtccttc gcgtgcacga acgcccagat cggggcgacg acgtcgaact cccccagcac
    25201 cggcagttcc gcggcgtcca ccgcgtcgta cgtgataccc agcggcgcct cggcctcgat
    25261 ctggcgggcg acgtcgacca tggactgctc gatgtccacg ccgacgacct tgtcggcgcc
    25321 cagccgcttg aaaatgcggg aatagaaacc ggttccgcac gccacgtcca gcacgcgctt
    25381 cccggtgagg tcgggaaccc cggagagcag cgtctcccgc tcgacaaagg cgtacggcag
    25441 gttcttgacg ttgtcgtact gcgtgctcga agcctggtac tgttcgctga tcctgtcgtg
    25501 gtggacgctc ttggtcatct tccgtgcctt tctgcggagc cgtcagcggt aggtgattcc
    25561 gaccgtagat acggctgagc gggcggacca tgttcagccg ttggatctgt caactcggaa
    25621 gaaattcagg agaatatctt ctggaccttg cgcgacaccc attcgctcac cgtcacggtg
    25681 tcgaaccgct cgacggcgga ggaatccgtg aacggccgca tcggctcgat ggaggcgtcg
    25741 tggttgggga ggtagaagaa ggggatggtg aggcgggagg tggtgtctcc gtgtgggggg
    25801 ttgacgacgc ggtgcatggt ggagacccag cgtccgccgg tccacagggc catgaggtcg
    25861 ccgatgttga cgacgaagct gccggggatg gcggcgacgt cgcgccaggt gtcttctccc
    25921 tggaggacct ggaggccgcc gcggtcgtcc tcctggtaga ggatggtgag gctgccgaag
    25981 tccgtgtgcg gaccgcgccg cagctggccg gggaggggcg gggtgtgctg cggggggtag
    26041 tagttgacgg cgacggatga tccgtggtgg tcgaacttgt cgtcgaagaa gtcctcgtcc
    26101 agttcgagtg ccagcgcgaa cagccgcatc aggtcggcgg ccagttcctc catcgcggcc
    26161 atgtagtcct gccaggcgcc ccggaacccc tcggggttct tcggccacac gttccggtgc
    26221 gtccagctcg cccactggtc accgagcccg gcgcgctcct cgtcgctcag ctccccggtc
    26281 acgtgggccg cgaacgtctc gcacaggtcg ggcggcgtct cctggtcgag gctgcgcgcg
    26341 agcgtgccgc cggccctgcg gtatccggac acccccgggc gggacgcgac gaggtccttc
    26401 tcctcctccg ggagcttgaa gaaggcgttc gtcgtcgtga acatgcggtc gacgaggtcc
    26461 cgggaaaccc cgtggccgac gacgatgaaa aagcccgaac tgcgcagtgc gtttccgatc
    26521 gcgtcggcaa tcgcggcgcg accctcgggg gttttccgcg aggagaggtc gatgaccggc
    26581 acgaacccat cggtcacggt gacggtcggc tgagcattac tcacgacttt tccttcctct
    26641 tgcatttccc gaggcttccg cgccgacgcc cgggaagtga tgtcccgccc gacggtaggt
    26701 ccggccggct gccggtcgcc acggccggtg gccgaatgtg tcaactcatc cgccgaccgt
    26761 acggtcccca cggtttgctc gatccttttc tttacgtctt tctgtcggta ccgctgccgc
    26821 aacagcggaa agccgacccg ttgccgaggt gcgcatgcgg gggagggcac ctcggcaacg
    26881 gatcggggtc ggggcacgcg cggcgtgtta cggggtgccg gcgaacatct tctggatctt
    26941 gcgggacatc cactccccgg cgatcacgct ggtgagatcg gtccggcgac tgcccaccgg
    27001 gccgccggcc gcgtccgggc acggccgcag cggttcgatc gtggcgtcgt ggttggggag
    27061 gtagaagaag gggatggtga ggcgggaggt ggtgtctccg tgtggggggt tgacgacgcg
    27121 gtgcatggtg gagacccagc gtccgccggt ccacagggcc atgaggtcgc cgatgttgac
    27181 gacgaagctg ccggggatgg cggcgacgtc gcgccaggtg tcttctccct ggaggacttg
    27241 gaggccgccg cggtcgtcct cctggtagag gatggtgagg ctgccgaagt ccgtgtgggg
    27301 gccccgccgc cactggccgg ggaggggcgg ggtgtgctgc ggggggtagt agttgacggc
    27361 gacggatgat ccgtggtggt cgaacttgtc gtcgaagaag tcctctttca gatcgagtgc
    27421 gagggcgaac agtcgcatca ggtccgccgc gagatcgctt atgacggcca tgtactcctg
    27481 ccacacctcc cggaagccgg cgggccgttc gggccagatg ttcgccagcg tccaggtcgc
    27541 ccactggtca ccgagcctgc cgcgctcgct gtcgctcagt tcccccgtca cgtgcgcgga
    27601 aaaggcttcg cacaggtcgg gcggcgtctc ctgatcgagg ctgagggcgg tggtgccgcc
    27661 ggtccgccgg tatccggaca cccccggccg gtgcgcgacg aggtccttct cctcgtccgg
    27721 cagggtgaag aaggctttcg tcgtggtgaa catgcggccg atgaggtctt cggggacacc
    27781 atgaccgacg atcacgaaga aaccggaact cgtgcacgcc tggtcgatcg cggtggcgat
    27841 cgcggcgcgt cctggggccg tgtctttcgc ggacaaatcg atgacgggta cgaaaccctc
    27901 ggcagcggtg gggggcagct gcgcattgtc catgggcctt gtttctcctt gttcggctgg
    27961 gggatggcct gagtgagcgg agagggacgg ttcagtgcgt ggactcgagg acggcctccg
    28021 gccggccctc gctgtcccgg cgccgggaga agagggcgac ggccaccgca ccggcgagga
    28081 ggatgccgaa ggcgacccac agcgccaccg tgtatccgtg cacggtcccg gcgttgacgg
    28141 attccgggcc ggccccgtgc tccttgaggt agtcaccggt gacgctggta gcgatcgagt
    28201 tgagcagagc ggtaccgaac gcggcgccca cctgctgcac cgtgttgtac gcggctgagg
    28261 cgacacccgc ctcggcgtgg cccagttcca ccgtcgccat gttggtcgcc gccgccagca
    28321 ggcagccgag tccgagcccc gtcaggatca tcgcgggggt cagatagacg aggaagacgt
    28381 tggagctgtc cacttccagc tgggtgagga tcagcatgcc gagggcggag gagagcaggc
    28441 tgcccgcgat cagcacgttc gccgggacgc ggccggtcag ctttccggcg atcagcatcg
    28501 cgccgatggt ggtgcacacg gcgttcacca gcagcgtcat gcccgccttg acgggtgagt
    28561 agccgaggat cgtctgcgtg tagtagctga cgaacaggta gaagccgaac atcgcgatga
    28621 acatcacgca cacggagacg aaggcgacgc cccgtgtgcg gtgggcgagg atgcgcagcg
    28681 gcagcagcgg gtgccccgtc cgggcctcga ccaggacgaa cagccccagc agcacgatgc
    28741 cgccgatcag cagggagagc accttcgggt cgccccagcc gtgcggttcg gcctgggtga
    28801 agccgtagac caggcagacg aggccggcga cgctgagcag caccccggga aggtccaggt
    28861 ggcgcagggt gccgctgggg cggtcccgga tgatgaacgg cacgcccagc agggcgaggg
    28921 cggccatcgg gacgttgatg tagaggcacc agcgccagtc ggtgtactcg gtgagcagac
    28981 cgccggccac cacgcccagg gccgcgccgc cggcgccgac cccggcgaac acaccgaagg
    29041 ccttcccccg ttcgcgcccg tcggtgaacg tcaggatcag cagggacagc gcggccggcg
    29101 ccaggagggc ggcgaagact ccctggcccg cgcgggcggc gaacagcatg cccgcggagt
    29161 tcgcggctcc gccgagcgcg gaggtcacgg cgaagccgat caggctgagg gtgaaggagc
    29221 ggcggtggcc gagggcgccg cacacccggc cgcccacgag cagcagcccg ccgaaggcga
    29281 gggcgtaggc ggtgatgacc cagtgccggt cggcgtccga cattcccagg tcctgctggg
    29341 ccgagggaag ggcgatgttc acgatggtcg cgtccagcac gaccatcagc tgggccaggc
    29401 tcacgacggg gagggcccac cagcgtttcg gggactgagc ggggggagcc ggggcttctt
    29461 gcttgatgtc tgtcacagtc actcgcacta tggtcgggtg tctcgaacgt tggtctagtg
    29521 acgagtgact ctactacaac tctgcgcagc gggacgtgac caaaaggggg tgcgaagcct
    29581 ctccccgggc ggcctggaga gcgttgaaat gcctggtcaa caggggggcg aagatttttt
    29641 caagaagtag gactgcggct cggtcccggt gcgccggtca cctggtacgg accgggggcc
    29701 agggcatgcg agactccagt gcacgctcgg tgcggcgtct cgcgccctgg gatcgggccg
    29761 cgtgatttcg gaggtgaacg tcatcgcaga caaagagcgc acgaagagcc ggtccggcgg
    29821 cggagtcggc aacgtctggc tgcgggcctc gcgggagaaa cagggcgaac ccccgttgac
    29881 gcgggcgcgt atcgtcgacg cggccgtcgc gctgctggac gacgagggca tgggccggct
    29941 gacgatgcga cggctggccg agcgcctcca ggtgggtgcc acgacgctgt actggcacgt
    30001 ggcgaccaag gacgacgtcg tcgatctcgc cgtcgacgcc atcttcggcg agacccaggt
    30061 ccccgaccgg cacgccgaca gtccgcgcga ggacatcgcc accctcgtcg acggctggcg
    30121 caaggccatg ctgcggcacc cctgggcggc caccctgccc gcgcgccaac ggccgctgat
    30181 ggggcccaac ttcctggcgt ggatggagtt cctgcagtcc gcgctggtcc gtgccggggt
    30241 gaccggcaag cggctgcacg ccgcgacctg ggcgctctac aaccatgtga tgggcgccac
    30301 cgccgcccag tccagcctcc agctctccgc cgaggagacc cggttggggc aggagtacct
    30361 ggagaacagg cgcgagcggt acccgaccgt cgccgcgaac aactacatcg ccgacgacga
    30421 ctgggacgcc aacttctcgc tcgggctgga gttcctgctc gacgggatcg aggcgggctc
    30481 ccggccctga
//
