BGC0001965: nybomycin biosynthetic gene cluster from Streptomyces albus subsp. chlorinus
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Location: 1 - 30,490 nt. (total: 30,490 nt).
This entry is originally from NCBI GenBank MH924838.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001965
Short description nybomycin biosynthetic gene cluster from Streptomyces albus subsp. chlorinus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other
Loci NCBI GenBank: MH924838.1
Compounds
  • nybomycin
Species Streptomyces albus subsp. chlorinus [taxonomy]
References
Chemical products information
nybomycin
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C16H14N2O4
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AYV61398.1
  • orf-04
 1 - 510 (-) hypothetical protein
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  • AYV61399.1
  • orf-03
 659 - 1006 (+) hypothetical protein
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  • AYV61400.1
  • orf-02
 1160 - 2428 (-) hypothetical protein
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  • AYV61401.1
  • orf-01
 2432 - 3322 (+) hypothetical protein
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  • AYV61402.1
  • nybA
 3807 - 5234 (-) 3-carboxy-ciscis-muconate cycloisomerase
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  • AYV61403.1
  • nybB
 5231 - 7240 (-) FAD-binding protein
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  • AYV61404.1
  • nybC
 7493 - 8470 (+) NADPH:quinone reductase
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  • AYV61405.1
  • nybD
 8545 - 10461 (-) anthranilate synthase
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  • AYV61406.1
  • nybE
 10458 - 11141 (-) isochorismatase
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  • AYV61407.1
  • nybF
 11337 - 12545 (-) DAHP synthase
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  • AYV61408.1
  • nybG
 12557 - 13396 (+) hypothetical protein
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  • AYV61409.1
  • nybH
 13220 - 13993 (-) vicinal oxygen chelate protein
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  • AYV61410.1
  • nybI
 14004 - 14672 (-) NAD\(P\)H:dehydrogenase
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  • AYV61411.1
  • nybJ
 14872 - 15279 (+) hypothetical protein
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  • AYV61412.1
  • nybK
 15461 - 16261 (-) N-acetyltransferase
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  • AYV61413.1
  • nybL
 16263 - 17264 (-) amidohydrolase
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  • AYV61414.1
  • nybM
 17565 - 18629 (+) acetoacetyl-CoA synthase
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  • AYV61415.1
  • nybN
 18685 - 19233 (+) aromatase/cyclase
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  • AYV61416.1
  • nybO
 19275 - 20927 (+) long-chain acyl-CoA synthetase
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  • AYV61417.1
  • nybP
 20924 - 22354 (+) salicylate hydroxylase
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  • AYV61418.1
  • nybQ
 22631 - 23761 (-) hypothetical protein
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  • AYV61419.1
  • nybR
 23974 - 24690 (-) NAD-dependent epimerase
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  • AYV61420.1
  • nybS
 24757 - 25518 (-) SAM-dependent methyltransferase
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  • AYV61421.1
  • nybT
 25626 - 26624 (-) isopenicillin N synthase family oxygenase
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  • AYV61422.1
  • nybU
 26908 - 27933 (-) isopenicillin N synthase family oxygenase
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  • AYV61423.1
  • nybV
 27992 - 29476 (-) MFS transporter
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  • AYV61424.1
  • nybW
 29762 - 30490 (+) transcriptional regulator
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Cleaned up synonym list
  • Fetch compound properties from PubChem
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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