BGC0001971: malyngamide I biosynthetic gene cluster from Okeania hirsuta
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Location: 1 - 62,331 nt. (total: 62,331 nt).
This entry is originally from NCBI GenBank MK142793.1.

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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General information about the BGC

MIBiG accession | BGC0001971
Short description | malyngamide I biosynthetic gene cluster from Okeania hirsuta
Status | Quality: questionable The quality level of this entry. Status: active The status of this entry. Completeness: unknown Whether the entry covers everything needed for the pathway producing the compound(s)

Biosynthetic class(es)

- NRPS (Type I)
- PKS (Unknown)

Loci
MK142793.1
283 - 62128
via
Compounds

- malyngamide I

Species Okeania hirsuta [taxonomy]
References

- [1] Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta. Moss NA et al., ACS Chem Biol (2018) PMID:30444349

Chemical products information
malyngamide I Evidence:
Copy SMILES
C26H42Cl1N1O5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production

Identifiers | Position | Product | Functions | Evidence | Extra
--- | --- | --- | --- | --- | ---
AZH23824.1 | 283 - 2622 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq
AZH23832.1 | 2912 - 3829 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq
AZH23834.1 | 4108 - 4857 (-) | MgiA |  |  | copy AA seq copy Nt seq
AZH23831.1 | 5263 - 6240 (-) | MgiB |  |  | copy AA seq copy Nt seq
AZH23838.1 | 6339 - 6713 (-) | MgiC |  |  | copy AA seq copy Nt seq
AZH23835.1 | 6873 - 7610 (+) | MgiD |  |  | copy AA seq copy Nt seq
AZH23836.1 | 8064 - 8600 (+) | MgiE |  |  | copy AA seq copy Nt seq
AZH23839.1 | 9004 - 9309 (+) | MgiF |  |  | copy AA seq copy Nt seq
AZH23820.1 | 9530 - 15238 (+) | MgiG |  |  | copy AA seq copy Nt seq
AZH23821.1 | 15489 - 20534 (+) | MgiH |  |  | copy AA seq copy Nt seq
AZH23818.1 | 20609 - 27163 (+) | MgiI |  |  | copy AA seq copy Nt seq
AZH23822.1 | 27160 - 31920 (+) | MgiJ |  |  | copy AA seq copy Nt seq
AZH23823.1 | 31996 - 35712 (+) | MgiK |  |  | copy AA seq copy Nt seq
AZH23840.1 | 35735 - 35974 (+) | MgiL |  |  | copy AA seq copy Nt seq
AZH23830.1 | 36016 - 37236 (+) | MgiM |  |  | copy AA seq copy Nt seq
AZH23829.1 | 37241 - 38500 (+) | MgiN |  |  | copy AA seq copy Nt seq
AZH23826.1 | 38670 - 40112 (+) | MgiO |  |  | copy AA seq copy Nt seq
AZH23833.1 | 40165 - 40929 (+) | MgiP |  |  | copy AA seq copy Nt seq
AZH23817.1 | 40917 - 49235 (+) | MgiQ |  |  | copy AA seq copy Nt seq
AZH23819.1 | 49292 - 55318 (+) | MgiR |  |  | copy AA seq copy Nt seq
AZH23837.1 | 55651 - 56151 (+) | MgiS |  |  | copy AA seq copy Nt seq
AZH23827.1 | 56584 - 57939 (+) | MgiT |  |  | copy AA seq copy Nt seq
AZH23828.1 | 58414 - 59724 (-) | hypothetical protein |  |  | copy AA seq copy Nt seq
AZH23825.1 | 60347 - 62128 (-) | hypothetical protein |  |  | copy AA seq copy Nt seq

Biosynthesis information

#### Biosynthetic modules

Name
Unk01
Type
nrps-type1
Genes
AZH23822.1
Substrates
glycine (evidence: Sequence-based prediction, Structure-based inference, Feeding study)
Integrated Monomers
Domains
adenylation
Annotation changelog

#### Entry version: 2

Date
Changes
Submitters
Reviewers
2022-09-15
Cleaned up synonym list

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

2022-09-15
Fetch compound properties from PubChem

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

2022-09-15
Added NRP substrate specificities

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

#### Entry version: 1

Date
Changes
Submitters
Reviewers
2019-10-16
Submitted

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

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