LOCUS       BGC0001990             13801 bp    DNA     linear   CON 18-APR-2022
DEFINITION  Aspergillus fumigatus Af293 chromosome 5, whole genome shotgun
            sequence.
ACCESSION   BGC0001990
VERSION     BGC0001990
KEYWORDS    .
SOURCE      Aspergillus fumigatus Af293
  ORGANISM  Aspergillus fumigatus Af293
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Fumigati.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to CM000173.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 05:50:48
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..13801
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001990"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..13801
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            complement(join(<131..655,723..>1814))
                     /db_xref="GeneID:3505488"
                     /locus_tag="AFUA_5G02620"
                     /note="transcript AFUA_5G02620A"
                     /old_locus_tag="Afu5g02620"
                     /product="P450 family sporulation-specific N-formyltyrosine
                     oxidase Dit2, putative"
                     /transcript_id="XM_742987.1"
     gene            complement(<131..>1814)
                     /db_xref="GeneID:3505488"
                     /locus_tag="AFUA_5G02620"
                     /old_locus_tag="Afu5g02620"
     CDS             complement(join(131..655,723..1814))
                     /EC_number="1.14.-.-"
                     /codon_start=1
                     /db_xref="GeneID:3505488"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 207.4; E-value: 6.6e-63)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_5G02620"
                     /note="encoded by transcript AFUA_5G02620A; similar to
                     N-formyltyrosine oxidase, sporulation-specific microsomal
                     enzyme required for spore wall maturation, involved in the
                     production of a soluble LL-dityrosine-containing precursor
                     of the spore wall, homologous to cytochrome P-450s; Dit2p
                     (GI:6320610) [Saccharomyces cerevisiae]"
                     /old_locus_tag="Afu5g02620"
                     /product="P450 family sporulation-specific N-formyltyrosine
                     oxidase Dit2, putative"
                     /protein_id="XP_748080.1"
                     /transl_table=1
                     /translation="MTWMRVMPRCQNRTYKRPRGPPLSIHPLEFFQAKKVEKTAKAKMI
                     LYYLASIPLAIICYLAWYLHVPWDLPSLPRIPFYVSILGLWSSMGQDEIYERWLRKPLE
                     AHGAVLIWFAGRWSILVTRPDLLTDMFRNEDLYAKAGSQKKIPWSVIATLVGDNIINSH
                     GDTWKLYTGIMKPGLQKKNFDTAPLLLKSRRFVDEILAEQNSAGRGTGILVNTFVQQWA
                     VDVMGMSFLDLDLQSLEKPHGTVRLEAIQSVIKLMLFRPLFFNFPDLDQFAWLIKSRQR
                     AYEIMHEFGDTLMATVLGRIDSDREKGIKPAEEMVVHMLVDAYRDGRLTEKQFKDNLKI
                     VFLTAHENAQQLVNSMFWEIGKNNEVQTRLRAEILSTNTTTPTSEVVNALPYLTAVVYE
                     LLRLYPPVSQLINRVTVRPAMLGNEIPIPAGTFVGWNAYGVHVNPAIWGPDANEFKPER
                     WGRTVGEMHARFRRETVRGTYIPFNAHSRKCLGQGFVLLQMKILLFEVLRRIEWTVDPG
                     YRLKMTPVSYFLESGRKSTDA"
     mRNA            join(<2040..2112,2172..>2779)
                     /db_xref="GeneID:3505487"
                     /locus_tag="AFUA_5G02630"
                     /note="transcript AFUA_5G02630A"
                     /old_locus_tag="Afu5g02630"
                     /product="conserved hypothetical protein"
                     /transcript_id="XM_742986.1"
     gene            <2040..>2779
                     /db_xref="GeneID:3505487"
                     /locus_tag="AFUA_5G02630"
                     /old_locus_tag="Afu5g02630"
     CDS             join(2040..2112,2172..2779)
                     /codon_start=1
                     /db_xref="GeneID:3505487"
                     /locus_tag="AFUA_5G02630"
                     /note="encoded by transcript AFUA_5G02630A"
                     /old_locus_tag="Afu5g02630"
                     /product="conserved hypothetical protein"
                     /protein_id="XP_748079.1"
                     /transl_table=1
                     /translation="MATEALHMHKDRLSAEDLDLKDPHVSSSLALFAIHNLIRRNLKAC
                     AEHAITVQPANIDAFVTYAKYTLHVLRDQLTSVDEIWFPVFAEHDPRFLAQKDAHDALY
                     QRITAVDAQLATPPAELGQNELLSAEIAAAFAELHELTDKQYDLEEDLINQLGRKVPMD
                     TIRGLEKKQEERRRADVKVYGHLWTAVYLLRGLDPKERAIFPPGIPKLIAGGMLTAGAM
                     QFRR"
     mRNA            join(<3346..3733,3785..3908,3957..4066,4115..4496,
                     4543..>4834)
                     /db_xref="GeneID:3505486"
                     /locus_tag="AFUA_5G02640"
                     /note="transcript AFUA_5G02640A"
                     /old_locus_tag="Afu5g02640"
                     /product="O-methyltransferase, putative"
                     /transcript_id="XM_742985.1"
     gene            <3346..>4834
                     /db_xref="GeneID:3505486"
                     /locus_tag="AFUA_5G02640"
                     /old_locus_tag="Afu5g02640"
     CDS             join(3346..3733,3785..3908,3957..4066,4115..4496,
                     4543..4834)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /db_xref="GeneID:3505486"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 222.3; E-value:
                     1.6e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_5G02640"
                     /note="encoded by transcript AFUA_5G02640A; similar to
                     SP:P55790: Sterigmatocystin 7-O-methyltransferase
                     [Aspergillus flavus]"
                     /old_locus_tag="Afu5g02640"
                     /product="O-methyltransferase, putative"
                     /protein_id="XP_748078.1"
                     /transl_table=1
                     /translation="MSTQHGPKSTRTNDLYELAVNISSTVEAFVGRLDAIGAERPNLDN
                     PFPEIIQDEGAQLARLKILRLCERLMALVQGPVQWLMFQNMAFLDAACVGAILDMGIHD
                     IIAPGPEPTSLDQIVEATGASKDILKRIMRVCTQRLVFDEIAPEQFIHNGVSLQFLAPP
                     VQALISHACDDGLRMAAHFTDSLKKTDWKGSDDPENTAFSLAFNTNKGLFDYFYTEDLA
                     RGQRFALGMAGSEIMKTLTEDMFPFESLPQGAKVVDVGGGRGHVSVRIAEKVPGLNFVV
                     QDDESMLEAGQAEGVPKAVKDRIEFMPHDFFNEQPVKGADVYLLRFILHDHSDSRCAKI
                     LSNIVDAMEPGKSRILIDDAIVPSFLGPESSRFFNLLDLYMLAGLNGKERTLEQWNYLI
                     QMVSPKLVLEKVWKTPNGGPESGTILELRLQE"
     mRNA            complement(join(<5098..5266,5383..5597,5665..>5751))
                     /db_xref="GeneID:5077151"
                     /locus_tag="AFUA_5G02650"
                     /note="transcript AFUA_5G02650A"
                     /product="uncharacterized protein"
                     /transcript_id="XM_001481439.1"
     gene            complement(<5098..>5751)
                     /db_xref="GeneID:5077151"
                     /locus_tag="AFUA_5G02650"
     CDS             complement(join(5098..5266,5383..5597,5665..5751))
                     /codon_start=1
                     /db_xref="GeneID:5077151"
                     /locus_tag="AFUA_5G02650"
                     /note="encoded by transcript AFUA_5G02650A"
                     /product="hypothetical protein"
                     /protein_id="XP_001481489.1"
                     /transl_table=1
                     /translation="MQAILETVSNLLPYHLLSYGALLGTELFQSFVNTKICYQALPMKE
                     FLALQKRVFPAYFRCQVGLVVLTAVTRPPYSILSFSQHIWDSVPLIAVGVTGALNCAMN
                     EDNSSTTDPAKIQQANKTFSRNHAMSIHLNAIALVATVWYGFTLSSSLLNGL"
     mRNA            join(<7911..8022,8086..8601,8660..>8988)
                     /db_xref="GeneID:5077152"
                     /locus_tag="AFUA_5G02655"
                     /note="transcript AFUA_5G02655A"
                     /product="conserved hypothetical protein"
                     /transcript_id="XM_001481440.1"
     gene            <7911..>8988
                     /db_xref="GeneID:5077152"
                     /locus_tag="AFUA_5G02655"
     CDS             join(7911..8022,8086..8601,8660..8988)
                     /codon_start=1
                     /db_xref="GeneID:5077152"
                     /locus_tag="AFUA_5G02655"
                     /note="encoded by transcript AFUA_5G02655A"
                     /product="conserved hypothetical protein"
                     /protein_id="XP_001481490.1"
                     /transl_table=1
                     /translation="MHSQTTKDEQSKDDSSNEKQDAIERRRLQNRLSQRNHRRKIRDRI
                     AKLQERVIASELRAVATLNGWDQASPPAASMMESKPQGDFDSNPLASVSEDPAISNPPQ
                     RNVSSNLCRSCCSLLNQMPSSSSLPSPTSPLPFDLGLTNGVDSTNSSPSTLLNSSPSSS
                     QLSPFSLDTSLSMTGLQSQNEFSFPPYPDPPGSQQYPHCPQYYVATEASLPHIMQRLGS
                     ATSHPKAIILIPHGHGYAPAPFTGANAADSTGLRSALNGNLNLQNPGRHCLRPDRSAKS
                     SDLGTSGDWMTAPSSTPFCPLHPSQSSSLDNYQSMML"
     mRNA            complement(join(<9515..11037,11088..>11850))
                     /db_xref="GeneID:3505484"
                     /locus_tag="AFUA_5G02660"
                     /note="transcript AFUA_5G02660A"
                     /old_locus_tag="Afu5g02660"
                     /product="pyoverdine/dityrosine biosynthesis protein,
                     putative"
                     /transcript_id="XM_742983.2"
     gene            complement(<9515..>11850)
                     /db_xref="GeneID:3505484"
                     /locus_tag="AFUA_5G02660"
                     /old_locus_tag="Afu5g02660"
     CDS             complement(join(9515..11037,11088..11850))
                     /codon_start=1
                     /db_xref="GeneID:3505484"
                     /locus_tag="AFUA_5G02660"
                     /note="encoded by transcript AFUA_5G02660A; similar to
                     pyoverdine biosynthesis protein PvcA (GI:39574163)
                     [Bdellovibrio bacteriovorus HD100] PMID: 14752164"
                     /old_locus_tag="Afu5g02660"
                     /product="pyoverdine/dityrosine biosynthesis protein,
                     putative"
                     /protein_id="XP_748076.2"
                     /transl_table=1
                     /translation="MIAVLQNPQNAAISYSGEPQEHNLLGSYETKAPNVETSEIAASSS
                     SSEAPEDLAEEHHRNEASLQQPLSEVDRHEQPAASDNTRSGLDIPPVTVSTPQSSDNPL
                     VESKEAVPVTFKDEGKGTKADPSHLLTEALETTNGEENSPISEDEATAIAVLKVIERYG
                     VNFEKTGESWQGLTSFIPTVVEQVKKREAVRMILPAFPFKSPNARDKVLGVMPDLGEEL
                     ALYHLNGLCENIGRVYEPGADVYISSDGLVYNDILGVPDETVWEYGEALRRMAVEKELH
                     HVKFIRLFELLEHPWIPLTSAEQAKSYYLAHAQCLRRELMYRFEDRSFDADAAIRSDND
                     TCLTYRGYIKFLTKDLAPQMDTQYTSKKARAAHIAQIARSMIVRGKMFAAAIKANRADY
                     VRLSIHESNGARKLSISLVPQVRGVLGYTPWHSSIAVDADGTLRAVHAEDVRETHELVY
                     KNGQPYYFREKSKLFDWVEDGLRVKFEPLYPCGLIIRPSDIDDSRPPPSISHLPMHKVR
                     QLSTGLSPVVLRGFRETLKEELYVQKASELGTILPWSFGIIQKVRDAGRTDKLGNNVTS
                     NEAMPMHYDGMFKFEEETDPVTGEVKRVQKPPGYQFFTCPATAPKGSGYTLFASSRLFF
                     RYLPLPWTTERLQKVTWGMDNDGFWDAKLKNLPLVVPHPVTGLPCMRWHQPWDSTKTKF
                     STCAVTIENDEQELASVVDDLTYDYRVCLRFSWEQGDLLVSDNTAMLHTRTGYKTNCER
                     ELWRIHFD"
     mRNA            complement(<12936..>13646)
                     /db_xref="GeneID:3505405"
                     /locus_tag="AFUA_5G02670"
                     /note="transcript AFUA_5G02670A"
                     /old_locus_tag="Afu5g02670"
                     /product="ThiJ/PfpI family protein"
                     /transcript_id="XM_742982.1"
     gene            complement(<12936..>13646)
                     /db_xref="GeneID:3505405"
                     /locus_tag="AFUA_5G02670"
                     /old_locus_tag="Afu5g02670"
     CDS             complement(12936..13646)
                     /codon_start=1
                     /db_xref="GeneID:3505405"
                     /locus_tag="AFUA_5G02670"
                     /note="encoded by transcript AFUA_5G02670A; contains a
                     ThiJ/PfpI domain"
                     /old_locus_tag="Afu5g02670"
                     /product="ThiJ/PfpI family protein"
                     /protein_id="XP_748075.1"
                     /transl_table=1
                     /translation="MSSTPPKKYYKVAVLLFEGVDILDFTAPMEVFTHTSHNRNPDNPD
                     RVFQINTIARSRTVNAKKALTVQTDLLLEDAMQGLADFDIMVVPGGPPSLLNALVASNP
                     REVELIRSFATLPPKTPDEPRVLFSICTGAFLVGAAGLLTGVSVTTHHRAIEKLREFCI
                     RVNGEGASPPEVSHKRYIDAGVLKVGSARLLTAAGVSSCLDASLYLVSQLTSLDMSAFI
                     SRVMEYDWKGQLSE"
ORIGIN
        1 aaatcttata cctagtctat gctttcacct gaattcttgt gtctatcagc tcctctgctc
       61 agccttgtca gctctccttg acctcgctca ggatcacgcg gcatcccaaa ggcgccagaa
      121 tcccgccctg tcatgcatca gtactcttcc tcccggattc cagaaaataa cttactggcg
      181 tcatcttcaa ccgatagccc gggtccaccg tccattcgat ccgtctcagt acctcaaaca
      241 gcagaatctt catttgcagc aacacaaacc cctgcccgag acacttcctc gaatgcgcat
      301 tgaaagggat atacgtgccg cgcaccgtct cccggcgaaa ccgcgcatgc atctcaccca
      361 ccgtccggcc ccatcgctcc ggcttgaatt cgtttgcgtc gggaccccag atcgccgggt
      421 tgacgtgcac tccgtatgca ttccagccga caaacgtgcc tgcaggaatg gggatctcgt
      481 taccgagcat ggcggggcgg accgtgacgc ggttgatgag ctgcgagacg ggagggtaga
      541 gacgcagaag ctcgtagacg acggctgtga gataggggag ggcgttgaca acttcggagg
      601 ttggcgttgt ggtgtttgtc gagaggattt cggcgcggag gcgtgtttgg acttccttca
      661 atcatgtcac caggtcagat cgcgttggct aggaagatgc ttaagaaggg aaaagggcat
      721 acgttattct tgccaatctc ccaaaacatc gagttaacca gctgctgggc gttctcgtgc
      781 gccgtcagaa acacaatctt gagattatcc ttgaactgct tctcggtcag tctgccgtcg
      841 cggtaggcat cgaccagcat atgcacgacc atctcctcgg cgggcttgat gcctttctcg
      901 cggtcgctgt cgatgcgacc cagcactgtc gccatgagtg tatccccgaa ctcgtgcatg
      961 atctcgtacg cacgctgccg cgacttgatc agccacgcga attggtctag atcgggaaaa
     1021 ttgaagaaca gcggccggaa cagcatcagc ttgatcacag actggatggc ttcgaggcgc
     1081 accgtgccgt gcggcttctc caggctctgc aggtccagat ccagaaagct catccccatg
     1141 acatccaccg cccactgctg gacaaacgtg ttcaccagga tgcccgtgcc gcgaccggca
     1201 gagttctgct ccgccagaat ctcatccacg aaccgccgcg acttgagcag cagcggcgcg
     1261 gtatcaaagt tcttcttctg cagcccgggc ttcatgatcc ccgtgtacag cttccaggtg
     1321 tcgccgtgcg aattgatgat gttgtcgccg accagtgttg cgatcaccga ccaggggatc
     1381 ttcttctggc tgcctgcttt tgcgtagagg tcctcgttcc gaaacatgtc tgttagcagg
     1441 tctgggcgcg tgacgagaat gctccatcgg ccggcgaacc agattaggac ggccccgtgg
     1501 gcttcaaggg gtttgcgcag ccagcgctcg tagatctcgt cttggcccat cgagctccag
     1561 agaccgagga tggaaacgta gaaggggatt cgcgggagtg agggcaggtc ccacgggacg
     1621 tggaggtacc atgccagata gcagatgatg gcgaggggga ttgaggcgag gtaatagaga
     1681 atcatctttg ctttggctgt cttttcgact ttttttgctt gaaagaactc gagtggatgg
     1741 atcgatagtg gtggtcctcg cggtctcttg tatgtacgat tttggcaacg aggcatcact
     1801 cgcatccaag tcatgaccta agacttgacg tggctgatcg tactcagtga tgggtgcagt
     1861 agcgtatgca tcccaagtca gcaaatccga gctgatgtca tctcaacgac tatccaagtc
     1921 atcgcgaagt gtagcaaatg tcatatatat ccatattgac ctcgaaaaca gacggactga
     1981 caaatagcaa gcactaagga catcatcttt gccccgtaac caaatcgacg tctagcaaca
     2041 tggcaaccga agctctacac atgcacaaag accgtctctc agctgaggac ctcgatctca
     2101 aagatcccca cggtagttct agcctccatc ctctctctct agcaaacaag ctcctaagtg
     2161 aaatgaaaca gtctcctcca gcctcgccct cttcgccatc cacaacctca tccgccgcaa
     2221 cctcaaggcc tgcgcagaac acgcaatcac agtgcaacca gcgaacatcg acgccttcgt
     2281 cacctacgca aagtacaccc tccacgtcct ccgcgaccaa ctcacctccg tcgacgagat
     2341 ctggttcccc gtcttcgcgg agcacgatcc ccgcttccta gcacaaaagg acgcacacga
     2401 tgccctgtac cagagaatca ccgcggtgga cgcgcagcta gccactcccc cagcggagct
     2461 aggccagaat gagctcctct ctgcggagat agcagcagcc tttgctgagc tgcacgagct
     2521 aactgacaag cagtacgatc tcgaagagga cctcatcaac cagctaggcc gcaaggtgcc
     2581 tatggacact atacgcggcc tggagaagaa acaggaggag agaaggagag ctgatgtcaa
     2641 ggtgtatggg catttgtgga cggctgtgta tcttctgcgg ggccttgacc cgaaggagag
     2701 ggcgattttc ccgccgggga ttccgaagtt gattgccggg gggatgttga cggcgggggc
     2761 aatgcagttt cggaggtgag ttactgtctt tacatgggtg cttgaagggt gtggctgact
     2821 ggttggaaag agagctgcag tttacgccga gattttgata aaggttgagg tggttgggtg
     2881 gtgggaacga ggttggattg gattccacag gggattgtta ctgttgttgt tcaggtgtgg
     2941 tctgcatatc agaattgtag atatgtcatt tgtcaacgaa ttgactaagt taattatatt
     3001 gttcactgtg tcagcagagt acgagttacg accaatgctg actgtagctg gcccggtgtg
     3061 tcagcacagt gtgtacagac gccatcttgt atgcggatgc acgatttatc ctcagcaatc
     3121 catgtcagcc gtaggtctaa tcgcaatgca gctgacaatg aagaaattgt cccaataagc
     3181 aggagtgacg gtgacggctt tgactctact tgcagatcct ctgtggatag ccaatatccc
     3241 tccagagggt ataagaaagt taacaaggtt tcttactcgg gagccaaaga catcatcaat
     3301 aatcgtaaca gaaagatagc ccatcgtacg acgtgaacca acgccatgtc cacacagcac
     3361 ggccccaagt ccacccgtac aaacgacctg tacgagctcg ccgtcaacat ctccagcacg
     3421 gtagaggcct ttgtcggaag gctggacgca atcggcgccg aacgacccaa cctagacaat
     3481 ccctttccag agatcatcca agatgaaggc gcgcagctgg cccggctaaa gattctgcgt
     3541 ctctgcgaac ggctgatggc tctggtccag ggtccggtcc aatggctcat gttccagaat
     3601 atggcgttcc tcgatgccgc ctgcgtcggg gcgattctgg acatggggat ccacgacatc
     3661 attgcgcctg gacccgaacc aacgtcgctg gatcagattg tagaggcgac gggggcctcg
     3721 aaggatattc taagtacgcg acgccggcta tctagtatgc aaagatcgag ctgacaacac
     3781 tcagagcgaa tcatgcgtgt ttgcacgcag agattggttt tcgatgagat tgcaccagag
     3841 cagtttattc ataacggagt gtcgttgcag ttccttgcgc ctccggtgca agcgctcatc
     3901 agtcatgcgt gagtagcgtg gtcttgtaag gtggacgatt gagctgatac cgctagatgt
     3961 gacgatggac tgcgcatggc agcgcatttc actgattctc tcaagaagac agattggaag
     4021 ggaagcgatg atccagaaaa tacggctttt agcctggctt tcaacagtga gtatcccccc
     4081 aactcgtcat acaattcgtg ctaaatcctc gcagcaaaca agggtctttt cgactacttc
     4141 tacaccgagg atctcgcccg tggtcagcgt ttcgccctcg gtatggcagg cagtgagatc
     4201 atgaagaccc tcacggagga catgttcccc ttcgagtctc tgccgcaggg cgcaaaagtg
     4261 gtggacgtcg gaggcggccg gggccatgtc agcgtacgca tcgcagagaa ggttcctggt
     4321 ctgaacttcg tcgtccaaga cgatgagtcc atgctagagg ctggtcaggc agaaggtgtc
     4381 cccaaagcag tcaaagatcg gatcgagttc atgccgcatg atttcttcaa tgagcagccc
     4441 gtcaaggggg cagatgtgta tctcttgcgg ttcatcctgc atgatcattc ggacaggtta
     4501 gttttgccaa caggaaggaa gaagtatggc taatagtccc agtcgctgtg cgaagattct
     4561 gtcgaacatc gtcgatgcaa tggagccggg aaagtcgcgg attctcatcg acgatgcgat
     4621 tgttcccagc ttcttgggtc cggagagttc tcggttcttt aacttgctgg atctctacat
     4681 gctggctggt ttgaatggaa aggagaggac tttggagcag tggaactact tgatccagat
     4741 ggttagtccc aagttggtgc tggagaaggt ttggaaaacg ccaaacggcg ggcctgaatc
     4801 ggggactatc ctggaactgc gactgcagga atgattcgcc gatatgtgtt gattggggcc
     4861 aaagatagat tcactactca attctacaat ggattgttgc agaagaattt gggttgtcct
     4921 tccgcagatc taaccgcagt tgctgagacc attcgataaa gaaagagttg cgattgttgc
     4981 attcatgctt tagtcaaagt atatatacaa gggtagttaa gtgatttgtg acacctcgat
     5041 catgaccaaa gaccatccga tgaacacaca gatcaccagt ctacggaagt gatgggctta
     5101 caacccattc agaaggctcg acgacaatgt aaacccatac caaacggttg caacaagagc
     5161 aatcgcattc agatggatcg acatagcgtg attgcgggaa aatgttttgt tggcctgttg
     5221 gatcttcgct ggatccgtcg tgctagagtt atcttcattc atggcacttt ctatttgcag
     5281 agtcagctgc catcgggtga gatatggcta agaacacgaa gcctaccgtg aagcgctctc
     5341 ctaataaaag cagtcttcgt agtccgggga ccaaaaacga accaattcag ggccccggtg
     5401 acacccaccg cgattaaagg aacagagtcc catatatgtt gcgagaacga gagtatgctg
     5461 taaggcggcc gagtgaccgc agtcaaaacg accaatccca cttgacagcg aaagtacgct
     5521 gggaagacgc gtttctggag agcgagaaac tctttcatag gaagggcttg gtagcagatt
     5581 ttagtgttga caaagctcta agcgaacaac gtgtcacttc gaattcataa tcaggaggga
     5641 cacgagggag ttctgcgctc tcacctgaaa gagttctgtc cccagaagag ctccatatga
     5701 aaggagatga tacggaagca gattactgac agtctcaagg atcgcctgca tgtcttctcg
     5761 tagtgccaga gatcttgctt ataatgtgac tgcttggagc ctgggaatag tgtcgattga
     5821 ttcagaggga aacagtcact cttcaacggt taacaaagca gacagagatg gcgagactgg
     5881 agcctgtaca gtaagaaagt cagcccagag ataagtgatt tggcagccac agacaaatat
     5941 ggctgcctta aggcaggggc cctgtaagaa ccttttcttt gtcctgtcac aactcctctt
     6001 tctgcaccct tctcagcatc aaccagaact aatcctacca tccatacata ctattactgc
     6061 ccttgaattc atctcataca catcactcag catctacaat tcgcttacga cctgttactg
     6121 atgaccaaag gatcgcagga tacgagaagt agggtgagat acaattccaa gacaggctct
     6181 tttctccttc agctcttggc tgctagagac atactcgtgt cagcttctca tcatcagctg
     6241 gtaacacgag tgcccctcac atgtgcccct cacgcagatt cgtgttccac tgccaagatc
     6301 gattgtagtc cgagctgttc aagcctcgac cgattacttg catctatggt gggcagattc
     6361 ccgccacctt atccagcttt tactgtcgga aagcagcgga tttcccggag atggtccttc
     6421 agaggcgctt cttaaccaat atggctcatg catccaaacc attgagttcg cattgccatg
     6481 tacctactga cgcgtctcgt gtatgtgact gaccaacgaa cgaacacgag gatgttagct
     6541 gacgggagat tgcctgctag ctgcgctaat tggttgatct cctcgcaccc tggtaaatcc
     6601 tgtcagatac tgttggaggg catcccgttt gggctgttca aggcctcgta ctttttaaga
     6661 ggcttctcga ctgcggcact gttgcctggc cgcggcacga acctggattt tccagcttaa
     6721 ccaatattct tccagccgcg ccttgggtat acgaggtatt tgatggtatt ccagtgagcc
     6781 tcgtagccat accccagacg atattcaaca ggtgatgtca gattcaatgc tccgaccatt
     6841 ctctgtgtta catgataacc ttggaagaga accaaacctt tacgatacaa gtgtcgtatt
     6901 tacttcgagc tgcaggatgc ttgtctatgg tttaccaggg gtgctctgca tgtcacaccg
     6961 tcatgcggac gcgcgtcaag gatgcatcgc tcaatgaaga ccaccggatc attgacttct
     7021 cggaccacac cgagaagggc gccttttcgg cggatctgca gcctcgaacc ggccgtattg
     7081 aaatgaggga aaaaaaaaaa agaagaaaaa aaaaaaagaa aggaaggaag aaaaaatctt
     7141 cctgacaatc ttcaggagga cagatgaggg agactggtgt gatgatcatg cgtcaccaca
     7201 agcctagagt ggagcatccg cgttcttagt cgtcgatact ttcagagttt acaatggttg
     7261 aacatcagac cccagatcta tagtccctat ggggtaatgc aactgcacta gtctcggctc
     7321 cgatatacga caatggacga cgttgcattg gccagagaga aacacgaact cgcgtggcct
     7381 cgcgggccct tgactacttt agctctgcag tgcattatca gtaatcctgg ccggtgatat
     7441 taatagggtc gatatgactc gtctgtaaat ggatgaggta atgccaaacc tcacctgtat
     7501 cgccccttct gtgattgaga taacctaccg agccaatgat cgctcctagc acgtcgcatc
     7561 agtcaagacc ccagggagcg tcttacttcc aagatgacta gtgttgactt gtcgactaca
     7621 tagcccggct cgcattggaa acttaatagg tgcgtcagcg agattcctgt caggcagcta
     7681 taaatgaatg cagtaacggc agggaagccc ttgatccttt tgatgatcaa cttggcgcgg
     7741 ctgatcatcg ctgagtgctg aggctttctg cgtaatcctc cttccagagg acagggcctg
     7801 ttcaacatag gtgggcctgt atagaaacct cgggctaaac ttcctgcctc gaaacttgcc
     7861 tcatcaaaag aaaccaaagt tacaaggcca aaaggccatt atcagcagcg atgcattcac
     7921 agactacaaa ggacgagcag tccaaagatg actcctcaaa cgagaagcaa gacgctattg
     7981 aacgcaggag acttcaaaat cggctatccc agagaaatca tcgtcagtgg aaccggtgtc
     8041 ttgttaatcc cattctcctc aatcactcac tcacccagtg aataggccgc aagatccggg
     8101 acaggatcgc caaacttcaa gaacgtgtta tcgctagtga gctcagagct gtcgcaactt
     8161 tgaatggatg ggaccaagcg agtccaccag ctgcgtcgat gatggaatcc aagccgcaag
     8221 gtgactttga tagcaacccg ttggcttctg tttcggaaga tccagcgatc tcgaatcctc
     8281 cccaacggaa cgtctcctcc aacctctgtc gttcgtgctg tagtctactc aaccagatgc
     8341 ccagttcgtc ctctctgcct tctccaactt cacctctgcc gtttgacctc ggtctcacca
     8401 acggggtgga ctccaccaac tcatcaccct ctactctcct gaactcttct ccctcatcgt
     8461 cacagcttag tcctttcagc ctagacacat ctttaagcat gacggggctt caatctcaga
     8521 atgaattcag cttcccgcca tatcctgacc ctccaggctc ccaacaatat ccacactgcc
     8581 cacagtatta tgtagcaaca ggtgaggcca ctgtctcaat atcaaaggac aacggactaa
     8641 ccactgtatc ccgctttaga ggcctcccta ccgcatatca tgcaaagatt gggtagtgca
     8701 acctcgcatc ccaaggccat catcttgata ccgcatgggc atggatatgc cccagcgcca
     8761 ttcacaggag caaacgcggc agactccaca ggcctcagaa gcgcgttgaa cggaaattta
     8821 aatctgcaaa acccaggacg ccactgccta agaccagacc gcagtgccaa atcttcggac
     8881 ctaggaacat ccggagattg gatgaccgcg ccgtcctcga ctccgttttg tccgctacat
     8941 ccttcacagt cgtcatcgtt ggacaattac cagtccatga tgctttgagt catatattcc
     9001 aacttaaatt ctatgcttct tatgtgtcta tgtttctgtg atgttattta tgaaaatttg
     9061 gccggatgag gtatatagta tagaccacac atggtgtgac aaggccctgg ccctgatgat
     9121 tgtatcggaa tgcttactac tttcttgtat gaatgttgaa atgaatactt tcttctttta
     9181 cgatcatttc atctctacgg tttcagagca tcctgtagtc cctctgagca caaggcaatt
     9241 ctaaatttga cactcgattt gacttccaat agttgccata acacactaca ggttatttga
     9301 ctgtctgaga atagatataa ggagaaggtg cctgtagacc tttgcagaca ttggttctaa
     9361 gtacctaagg agcgtagaac aatatacgtg actgcttaat gcaataagaa cttgatgcga
     9421 aatgagaagg gaacgaagca aatcagcaaa ggcgataact tcgagagcca gtgattgtac
     9481 agaagcaacc tggctccaac agatcagttg agaattagtc aaagtggatt ctccacagct
     9541 cccgctcaca attcgtcttg taccccgtcc gggtatgcag catggctgta ttatcactga
     9601 cgagcagatc accctgctcc caagagaagc gcagacagac gcggtagtca tacgtcaggt
     9661 catccaccac cgaggccagc tcctgctcgt cgttctcgat cgtgaccgca caggtcgaga
     9721 acttggtctt ggtggaatcc cacggctggt gccagcgcat gcacggcagc ccggtgaccg
     9781 ggtgcggcac caccaggggc agattcttca gcttggcgtc ccagaagccg tcgttgtcca
     9841 tgccccaggt caccttctgc agccgctcgg tggtccacgg cagaggcagg tagcggaaga
     9901 agagccggga gctggcgaag agggtgtacc cgctgccctt gggcgcggtg gccggacagg
     9961 tgaagaactg gtatcccggg ggcttttgga cgcgcttaac ctcccctgtg acggggtctg
    10021 tctcctcttc gaacttgaac atgccgtcgt agtgcattgg cattgcctcg ttggaggtga
    10081 cgttgttgcc gagcttgtcg gtgcggccgg cgtcgcgcac cttttggatg atgccgaagc
    10141 tccaggggag gatggtgccg agctcggatg ctttctggac gtatagctct tctttgaggg
    10201 tttcgcggaa gccgcgcaga acgaccgggg agagtcccgt agagagctgg cggactttgt
    10261 gcattggcag gtggctgatg gatggagggg gtcgcgagtc gtcaatgtcg ctgggccgga
    10321 tgatgaggcc gcaggggtac aggggctcga acttgacccg caggccatcc tcgacccagt
    10381 cgaagagctt ggacttctcc cggaagtagt atggctggcc gttcttgtag actagctcgt
    10441 gcgtctcacg cacatcctcg gcgtgaactg cgcggagtgt gccgtcagcg tcgactgcaa
    10501 tcgacgaatg ccatggtgtg tacccgagga cgcctcggac ctgtgggacg agcgagatgg
    10561 acagtttcct tgccccgttt gactcgtgga tggagagacg gacataatcg gcacggttgg
    10621 ccttgatggc ggcagcaaac atctttccgc ggacgatcat gctacgagca atctgggcga
    10681 tatgagctgc tctggccttt ttactcgtat actgcgtgtc catttgagga gccaggtcct
    10741 tggtcaggaa cttgatgtac ccgcgatatg tgaggcaggt atcattgtca ctgcggatag
    10801 ccgcatcagc gtcgaagctg cggtcctcaa accggtacat caactctctt cggaggcatt
    10861 gcgcatgcgc caggtaatat gacttggctt gttcagcgct ggtcagagga atccaggggt
    10921 gttcgagaag ctcaaacagt cggataaact tgacatgatg aagctccttc tcgacggcca
    10981 tcctgcggag ggcttctcca tattcccaga cagtctcgtc aggtactccg aggatatcta
    11041 ttattggtta gcacggtgaa accgtggtga gtgcaggaga gacttgccat tgtatacgag
    11101 tccatccgag ctgatatata catctgcacc cggttcgtag actcttccaa tgttctcgca
    11161 caggccattc aaatgatata acgcgagctc ctctccgaga tctggcatca cacccaagac
    11221 cttgtctcga gcattggggg acttgaacgg gaaagccggg aggatcatcc gaacagcttc
    11281 ccgctttttg acttgctcaa ccacggtggg aatgaacgag gtcaggccct gccaggactc
    11341 gccagtcttc tcaaagttca ccccataacg ttcgatgact ttcaggacag caatcgctgt
    11401 tgcttcgtct tcggagatgg gactgttctc ctctccgttg gtggtttcga gggcctcggt
    11461 taggaggtgc gaggggtcag ccttggtccc tttgccctcg tctttgaacg tgactgggac
    11521 tgcctccttt gattcaacaa gcggattgtc gctactttgg ggggtggaga cggttacagg
    11581 aggaatgtcc aacccggacc gtgtgttgtc gcttgcggca ggctgctcgt gccgatcaac
    11641 ttcgctcaat ggctgctgca gagaggcctc attgcgatgg tgctcctcag cgaggtcttc
    11701 aggagcttca gaggaggacg aggaagcagc gatttcactc gtctcaacgt tcggggcttt
    11761 tgtttcatac gagccaagta ggttatgctc ttgtggctcc ccggaatatg agatggcagc
    11821 gttctgtggg ttctgcagta cggcaatcat atcgacgaag aaagaaagaa aaaaaaaatg
    11881 tgaagaatga cactttatgt aaagactggt gatgttcctt tctcagttgg tatgttatgt
    11941 actgtgttgt gtacttccga gggtgacttc gtcctatccc catccgtcgg tatgcacggt
    12001 tttatatctt tctagaaagg aagagacgag gccagacata gtgaggaaaa cgaagcctcg
    12061 tcagctatta catcaatgac gtcgaaagag ctgaagatcc caactgttgt gacattgttg
    12121 actaacaagc aacctcactg tatgctgcca tacgctacaa atacaccctc tctgcttgaa
    12181 ttttggcagt cagcatgatc cacagctgaa taatcccagt gatagaagga tctaccggga
    12241 ggctggtcag tctccatgtc ttctgtacct gggccatggc cgtgaagctg aacctgattc
    12301 cgatagaagc cttgaaagag aacacgaggt agctgacacg gagccttggg agatgacaag
    12361 acctgcagct gcttaggcag atatcctcgg ctctgacaaa cgagatatct atcagtgcct
    12421 tcgagccaca tccatgtgcg cgtcgtctca cggcacccaa tgtagagcca agcaccttgg
    12481 agggggtctg ggtcacagtc aggtccaata tcacattgaa cgcttcagct gctgtggacg
    12541 gcccagtcag cagacatgct gcagattcgt ggaacggctg gaactgtctg tggggttaca
    12601 cgttcgccac gttctctacg agcacagcat ccagggcgag gttcttggcc agggtgtcgg
    12661 gctgtggccc catgtagtaa cagatacgca aagactgtct ctcgagagca cggtctcact
    12721 gtcttactgg agagaggctg taccaagatc tagggtcgat cctgtagaaa tgtgactcag
    12781 gctgactcta cagaacaggc cgaaggaagc ttttcagaca aaaattgaat ttgcacagac
    12841 aataaaggag ggtcgagaac gcatcgaacc catcccttac caaaagaact ctcagctagc
    12901 ttgtagcaag tgagatcgcc tctttgggag atcccttact cagaaagctg ccctttccag
    12961 tcatattcca tcacgcgcga gatgaatgcc gacatatcaa gggaagtcaa ctgactaaca
    13021 agatacaagg atgcatccaa gcagctgctc actcctgccg ccgtcagtag cctggcggaa
    13081 ccaactttta gaacacctgc atctatgtag cgcttgtgcg acacctcagg aggggaagcc
    13141 ccttctccgt ttactcggat gcagaactcc cgaagtttct caatggcacg atggtgagtc
    13201 gtgaccgaaa ccccagtaag aagccctgcc gctccaacta gaaacgcgcc agtgcaaatt
    13261 gagaaaagca cacgcggttc atctggcgtc ttgggaggga gtgtggcaaa gctgcgaata
    13321 agctctacct cccgggggtt ggacgcgacg agtgcattga gaagagatgg tggcccacca
    13381 gggactacca taatgtcgaa atccgcaagg ccctgcatgg cgtcctcaag caagagatcc
    13441 gtctggaccg tgagggcctt cttggcgttc actgttcgtg atcgagcaat agtgttgatc
    13501 tggaaaaccc tgtccgggtt atccgggttt cgattgtggg atgtatgagt gaaaacttcc
    13561 ataggggccg tgaaatcaag gatgtccact ccttcgaaga gtaaaacggc caccttgtag
    13621 tacttctttg gcggggtaga agacatggtg aaggacaatc tctcgcctgg ttggactcgg
    13681 acgctggtcg tcgagtgtag tcaataatgc gattctgaca accacgatcg cgaatatgtc
    13741 caaagaaaat gctgttgaac cgactgagct tagaaagtaa ggtactgatc tgatatttga
    13801 t
//
