LOCUS       BGC0001991             25209 bp    DNA     linear   CON 12-MAR-2023
DEFINITION  Methylorubrum extorquens AM1 megaplasmid, complete sequence.
ACCESSION   BGC0001991
VERSION     BGC0001991
KEYWORDS    .
SOURCE      Methylorubrum extorquens AM1
  ORGANISM  Methylorubrum extorquens AM1
            Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
            Methylobacteriaceae; Methylorubrum.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP001511.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:40:41
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..741
                     /NRPS_PKS="Domain: PKS_KR (8-171). E-value: 3.5e-11. Score:
                     35.2. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS33125_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     144.6; E-value: 6e-44)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF006118.0"
                     /locus_tag="MEXAM1_RS33125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_003598534.1"
                     /transl_table=11
                     /translation="MEIKDCIAFVTGANGGIGSALVSELLRRGVRRVYAASRSPRAETP
                     GTAEAPGRLPLLLDVVDSSSVSSAARLAHDVTLLFNNAGSMTRGSLLKTKLADVRGDME
                     ANFFGTYQMVRAFAGVIERNGGGGIVNILSVSAWASSPDAAGYSASKAAAHSLTQSLRA
                     ELAPRGVAVLAAYPGPVNTPMTRDLEIPKADPNEVARSIVDGVENDQEDIVPDRMSRQA
                     ADAWRRDPKVLERQFASLYSAGTM"
     protocluster    1..25209
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[796:19074]"
                     /cutoff="20000"
                     /detection_rule="(cds(PKS_AT and not (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and
                     (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
                     or cds(tra_KS and PP-binding)))"
                     /neighbourhood="20000"
                     /product="transAT-PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      797..19074
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PKS_AT and not (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and
                     (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
                     or cds(tra_KS and PP-binding)))"
                     /neighbourhood="20000"
                     /product="transAT-PKS"
                     /protocluster_number="1"
     cand_cluster    1..25209
                     /SMILES="C=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(PKS_AT and not (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and
                     (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
                     or cds(tra_KS and PP-binding)))"
                     /kind="single"
                     /product="transAT-PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..25209
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001991"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25209
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="transAT-PKS"
                     /region_number="1"
                     /rules="(cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or
                     ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or
                     cds(tra_KS and PP-binding)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..741
                     /locus_tag="MEXAM1_RS33125"
     aSDomain        25..513
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS33125_PKS_KR.1"
                     /evalue="3.50E-11"
                     /label="MEXAM1_RS33125_PKS_KR.1"
                     /locus_tag="MEXAM1_RS33125"
                     /protein_end="171"
                     /protein_start="8"
                     /score="35.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="FVTGANGGIGSALVSELLRRGVRRVYAASRSPRAETPGTAEAPGR
                     LPLLLDVVDSSSVSSAARLAHDVTLLFNNAGSMTRGSLLKTKLADVRGDMEANFFGTYQ
                     MVRAFAGVIERNGGGGIVNILSVSAWASSPDAAGYSASKAAAHSLTQSLRAELAPRGVA
                     "
     CDS_motif       28..117
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS33125_0001"
                     /evalue="6.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="MEXAM1_RS33125"
                     /protein_end="39"
                     /protein_start="9"
                     /score="22.0"
                     /tool="antismash"
                     /translation="VTGANGGIGSALVSELLRRGVRRVYAASRS"
     gene            797..7633
                     /locus_tag="MEXAM1_RS25395"
                     /old_locus_tag="MexAM1_META2p0008"
     CDS             797..7633
                     /NRPS_PKS="Domain: PP-binding (19-85). E-value: 3.2e-12.
                     Score: 38.7. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25395_PP-binding.1"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (161-589). E-value:
                     5e-163. Score: 534.8. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25395_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_DH2 (757-970). E-value: 1.1e-17.
                     Score: 56.0. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25395_PKS_DH2.1"
                     /NRPS_PKS="Domain: PKS_KR (1245-1428). E-value: 6.6e-44.
                     Score: 141.9. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25395_PKS_KR.1"
                     /NRPS_PKS="Domain: PP-binding (1521-1586). E-value:
                     3.4e-14. Score: 45.0. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25395_PP-binding.2"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (1638-2057).
                     E-value: 3.1e-153. Score: 502.5. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25395_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_DHt (2113-2250). E-value: 5.6e-12.
                     Score: 37.9. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25395_PKS_DHt.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047:phosphopantetheine-binding domain-containing
                     protein (Score: 42; E-value: 1.4e-12)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003598535.1"
                     /locus_tag="MEXAM1_RS25395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MexAM1_META2p0008"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_003598535.1"
                     /sec_met_domain="tra_KS (E-value: 1e-170, bitscore: 557.7,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 8.7e-41, bitscore:
                     129.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.7e-15, bitscore:
                     45.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMHTANSKDAHETKLLLQQWVSSTICDVTGLDGDRVGPNARLEE
                     IGLDSLAIVSFGTRLEQHIQGLRRSFIFDCRTVGEICDHLLTHHQPELGFLISQAASTP
                     KQLGERPFQKGADPASEAEDWPEIALADFGTGRETAQSHEMSPRESIQRDRLHLDNAVA
                     IIGMQGQFPGAASLDAFWQQIASGADLVGEIPADRWSVEGFYEAGSASRKTGKSYSKWG
                     AFLPGVDEFDAQFFGIPPRDARLMDPQERLFLECAYHAMEDAALLGARQESLRRDVGLN
                     IGVFVGITTNTYNLQGPSHWTAGGVEVPTSMPWSSANRVSYFLNLSGPSVAVDTACSSS
                     LVALHLAVESVAAGECAAAIAGGVNLYLHPAKYVQLCQYQMLSPTGRCHSFGADADGFV
                     PGEGVAAVVLRPLRDALQNGDRILGVIRGTAVNHSGRTNGYTVPGAASQAALIRKALDR
                     AALTPDSIGYIEAHGTGTKLGDPIEITGICDALGDSGQPCAIGSLKSNIGHLESAAGIA
                     GIVKVLLQLRHDRIAPSIHSRIPNPDLKLDGGRYFVPQDLGPWPKAASDGRRRAGISSF
                     GAGGTCAHAIIEEGPEVPVSSAVGPLVFPLSAQSPEQLRLRAQDLLKWVGMVQPGDERT
                     TLLRLAYTLQCGRATYRYRFAAAAASVRDLAAAVGTFLGEVATVAILGSQGVEDSEDAR
                     LAARWSTGEEVPWPTLWQGLPCPVGGLLYPFLRDRHALAPPEIRMDSGRERPGEQVEIV
                     VSHTFTGDESYIRDHVIGNSPILPGTAYVGLCSVLIGQAGGDGWAFDLQDLAWSSPYRW
                     VPTAAKQLLVRGRRLGPSLSIEIASSSDARPLHFTARADLGGRSPTADGEPIPAIRERC
                     TRSADVAGFYALAADFGMVFGESFRCIARASKGRGEALVEAKLPTGSRRGGTTGLPIDP
                     GLLDAVFQSAFFSVEEGFDGPHVPVRAKAVRIHGDLGSNLVIHVRAVAQASDGFTFDYR
                     LLAPSGAVIGEIEALTFQRIEAVRGRSALAERSINIFEPVWLPDAAVGFGGPPTALLAL
                     GRQDRNDIRLGLTGGTTQVRLRPGGAFEIDGSRTVTLDPERKDHLEHLWRTFKADGSLP
                     AAVVADLRHQPAVSPHGLERHLGLGPFIGAMALLKSVVEAYAPSKSCRMILICQGPAAS
                     AAAAMMRSVHIEAPSLDFTVLETDGAEHPAYLDQFVDAEAKRTAGGGVRHVRFIGGTPL
                     VRRYAALDLPSRDADVRSGDVVLITGGLGAVGLHIAKHLALHRGVRIALLGRSRPAEHS
                     RAAVASLRMAEGDCSYWECDCSSGEDLTQTLADIRSRMGPLTGILHCAGVLKDAFFTRH
                     TDTERYEVLKSKALSARLLDEMTRQDPLRWFVLSSALAAVCGNIGQSVYGLSNGWLDGF
                     AEERNSLTAAGRASGRTVAVAWPLWNTRTGMQASERFLRRLQDEGLDLLEPDEGARLFA
                     AATWSDRSLIVPIKGDEERSSRILGIKDAGIPAGNTDDATLEPQPGTADANGGQEDRVL
                     RYLIGTLSDVTGTAPERIEPDTPLEAFGLDSLLVLEMSDRLQERFPRIARTALFEARTL
                     RALARLLIDELPLDVAKLVASGVSVEDDEPLEEPTRPAVSAAVVGGSPEPGSTTGNRPA
                     IAIVGLAGRYPGSADLWDLWDHLCAGSDLVTELPPRLSAGEERNGVYAKWGSFIDDVDT
                     FDPLFFGISPRDAERMDPQERIFLQTAWHAVEDAGYTPEGLSGGSERGTRRRVAVIAGV
                     MYGEYQFFGAAGTSEGGALTNSSYASIANRVSYCLDFDGPSFAVDSMCSSSLTSMHLAC
                     ELLQSGGCDIALAGGVNISVHPYKYRMLSELKFAATDGRCRSFGVGGDGYVPGEGCGVV
                     VLRPLEAALAAGDHIYGVIRGSDIGHGARSSGYTVPNPDAQAEVVRRAFERSGVDPARL
                     SYIEAHGTGTSLGDPIEIRGLSKALGRQFPEGGTCAIGSIKANIGHLESAAGIAGLTKV
                     LLQMKHRRLVPSIHSAELNPFIDFNQTPFRVQREQAEWQAVGGRRLAAVSSFGAGGANA
                     HLVVESWDHPTMPEVASREPLALLLSSANEGQLREAARVLLKHLEREGEISPDAGQYWI
                     GSQHFSLRDVALTLLHGRRHGDHRLAIIAADFDEFRRKLALFIRTDSNVGAASGDFERL
                     GILIGGLQPTVQGDAIYREARAWVDGGPPPPPEAPWRRVPLPGYVFQRRRFWLGSLPAE
                     NEDPDKAVVDLHRSPPKTKDPDLTPSGIIAKVKAGDMTQETARELLLAMR"
     aSDomain        854..1051
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25395_PP-binding.1"
                     /evalue="3.20E-12"
                     /label="MEXAM1_RS25395_PP-binding.1"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="85"
                     /protein_start="19"
                     /score="38.7"
                     /tool="antismash"
                     /translation="QWVSSTICDVTGLDGDRVGPNARLEEIGLDSLAIVSFGTRLEQHI
                     QGLRRSFIFDCRTVGEICDHL"
     aSDomain        1280..2563
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25395_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="5.00E-163"
                     /label="MEXAM1_RS25395_PKS_KS.1"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="589"
                     /protein_start="161"
                     /score="534.8"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="VAIIGMQGQFPGAASLDAFWQQIASGADLVGEIPADRWSVEGFYE
                     AGSASRKTGKSYSKWGAFLPGVDEFDAQFFGIPPRDARLMDPQERLFLECAYHAMEDAA
                     LLGARQESLRRDVGLNIGVFVGITTNTYNLQGPSHWTAGGVEVPTSMPWSSANRVSYFL
                     NLSGPSVAVDTACSSSLVALHLAVESVAAGECAAAIAGGVNLYLHPAKYVQLCQYQMLS
                     PTGRCHSFGADADGFVPGEGVAAVVLRPLRDALQNGDRILGVIRGTAVNHSGRTNGYTV
                     PGAASQAALIRKALDRAALTPDSIGYIEAHGTGTKLGDPIEITGICDALGDSGQPCAIG
                     SLKSNIGHLESAAGIAGIVKVLLQLRHDRIAPSIHSRIPNPDLKLDGGRYFVPQDLGPW
                     PKAASDGRRRAGISSFGAGGTCAHAIIEE"
     aSModule        1280..5554
                     /complete
                     /domains="nrpspksdomains_MEXAM1_RS25395_PKS_KS.1"
                     /domains="nrpspksdomains_MEXAM1_RS25395_PKS_DH2.1"
                     /domains="nrpspksdomains_MEXAM1_RS25395_PKS_KR.1"
                     /domains="nrpspksdomains_MEXAM1_RS25395_PP-binding.2"
                     /locus_tags="MEXAM1_RS25395"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1778..1825
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0001"
                     /evalue="1.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="343"
                     /protein_start="327"
                     /score="20.3"
                     /tool="antismash"
                     /translation="GPSVAVDTACSSSLVA"
     CDS_motif       1967..2005
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0002"
                     /evalue="8.80E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="403"
                     /protein_start="390"
                     /score="9.5"
                     /tool="antismash"
                     /translation="FGADADGFVPGEG"
     CDS_motif       2198..2245
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0003"
                     /evalue="1.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="483"
                     /protein_start="467"
                     /score="13.9"
                     /tool="antismash"
                     /translation="YIEAHGTGTKLGDPIE"
     CDS_motif       2297..2341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0004"
                     /evalue="1.80E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="515"
                     /protein_start="500"
                     /score="10.9"
                     /tool="antismash"
                     /translation="GSLKSNIGHLESAAG"
     aSDomain        3068..3706
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25395_PKS_DH2.1"
                     /evalue="1.10E-17"
                     /label="MEXAM1_RS25395_PKS_DH2.1"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="970"
                     /protein_start="757"
                     /score="56.0"
                     /tool="antismash"
                     /translation="FTGDESYIRDHVIGNSPILPGTAYVGLCSVLIGQAGGDGWAFDLQ
                     DLAWSSPYRWVPTAAKQLLVRGRRLGPSLSIEIASSSDARPLHFTARADLGGRSPTADG
                     EPIPAIRERCTRSADVAGFYALAADFGMVFGESFRCIARASKGRGEALVEAKLPTGSRR
                     GGTTGLPIDPGLLDAVFQSAFFSVEEGFDGPHVPVRAKAVRIHGDLGSNL"
     CDS_motif       3086..3142
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0005"
                     /evalue="4.50E-06"
                     /label="PKSI-DH_m2"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="782"
                     /protein_start="763"
                     /score="19.3"
                     /tool="antismash"
                     /translation="YIRDHVIGNSPILPGTAYV"
     CDS_motif       3278..3313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0006"
                     /evalue="2.10E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="839"
                     /protein_start="827"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="GPSLSIEIASSS"
     CDS_motif       4532..4630
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0007"
                     /evalue="3.90E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="1278"
                     /protein_start="1245"
                     /score="29.1"
                     /tool="antismash"
                     /translation="VVLITGGLGAVGLHIAKHLALHRGVRIALLGRS"
     aSDomain        4532..5080
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25395_PKS_KR.1"
                     /evalue="6.60E-44"
                     /label="MEXAM1_RS25395_PKS_KR.1"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="1428"
                     /protein_start="1245"
                     /score="141.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VVLITGGLGAVGLHIAKHLALHRGVRIALLGRSRPAEHSRAAVAS
                     LRMAEGDCSYWECDCSSGEDLTQTLADIRSRMGPLTGILHCAGVLKDAFFTRHTDTERY
                     EVLKSKALSARLLDEMTRQDPLRWFVLSSALAAVCGNIGQSVYGLSNGWLDGFAEERNS
                     LTAAGRASGRTVAVAWPLWN"
     CDS_motif       4907..5014
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0008"
                     /evalue="9.20E-10"
                     /label="PKSI-KR_m4"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="1406"
                     /protein_start="1370"
                     /score="31.1"
                     /tool="antismash"
                     /translation="LRWFVLSSALAAVCGNIGQSVYGLSNGWLDGFAEER"
     aSDomain        5360..5554
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25395_PP-binding.2"
                     /evalue="3.40E-14"
                     /label="MEXAM1_RS25395_PP-binding.2"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="1586"
                     /protein_start="1521"
                     /score="45.0"
                     /tool="antismash"
                     /translation="YLIGTLSDVTGTAPERIEPDTPLEAFGLDSLLVLEMSDRLQERFP
                     RIARTALFEARTLRALARLL"
     aSDomain        5711..6967
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25395_PKS_KS.2"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="3.10E-153"
                     /label="MEXAM1_RS25395_PKS_KS.2"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="2057"
                     /protein_start="1638"
                     /score="502.5"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAIVGLAGRYPGSADLWDLWDHLCAGSDLVTELPPRLSAGEERNG
                     VYAKWGSFIDDVDTFDPLFFGISPRDAERMDPQERIFLQTAWHAVEDAGYTPEGLSGGS
                     ERGTRRRVAVIAGVMYGEYQFFGAAGTSEGGALTNSSYASIANRVSYCLDFDGPSFAVD
                     SMCSSSLTSMHLACELLQSGGCDIALAGGVNISVHPYKYRMLSELKFAATDGRCRSFGV
                     GGDGYVPGEGCGVVVLRPLEAALAAGDHIYGVIRGSDIGHGARSSGYTVPNPDAQAEVV
                     RRAFERSGVDPARLSYIEAHGTGTSLGDPIEIRGLSKALGRQFPEGGTCAIGSIKANIG
                     HLESAAGIAGLTKVLLQMKHRRLVPSIHSAELNPFIDFNQTPFRVQREQAEWQAVGGRR
                     LAAVSSFGAGGANAHLVVES"
     aSModule        5711..7546
                     /domains="nrpspksdomains_MEXAM1_RS25395_PKS_KS.2"
                     /domains="nrpspksdomains_MEXAM1_RS25395_PKS_DHt.1"
                     /incomplete
                     /locus_tags="MEXAM1_RS25395"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       6179..6223
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0009"
                     /evalue="2.50E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="1809"
                     /protein_start="1794"
                     /score="13.5"
                     /tool="antismash"
                     /translation="GPSFAVDSMCSSSLT"
     CDS_motif       6368..6406
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0010"
                     /evalue="2.70E-01"
                     /label="PKSI-KS_m4"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="1870"
                     /protein_start="1857"
                     /score="5.2"
                     /tool="antismash"
                     /translation="FGVGGDGYVPGEG"
     CDS_motif       6485..6514
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0011"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m6"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="1906"
                     /protein_start="1896"
                     /score="-3.5"
                     /tool="antismash"
                     /translation="DIGHGARSSG"
     CDS_motif       6599..6646
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0012"
                     /evalue="2.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="1950"
                     /protein_start="1934"
                     /score="13.4"
                     /tool="antismash"
                     /translation="YIEAHGTGTSLGDPIE"
     CDS_motif       6707..6751
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25395_0013"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="1985"
                     /protein_start="1970"
                     /score="11.3"
                     /tool="antismash"
                     /translation="GSIKANIGHLESAAG"
     aSDomain        7136..7546
                     /aSDomain="PKS_DHt"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25395_PKS_DHt.1"
                     /evalue="5.60E-12"
                     /label="MEXAM1_RS25395_PKS_DHt.1"
                     /locus_tag="MEXAM1_RS25395"
                     /protein_end="2250"
                     /protein_start="2113"
                     /score="37.9"
                     /tool="antismash"
                     /translation="HFSLRDVALTLLHGRRHGDHRLAIIAADFDEFRRKLALFIRTDSN
                     VGAASGDFERLGILIGGLQPTVQGDAIYREARAWVDGGPPPPPEAPWRRVPLPGYVFQR
                     RRFWLGSLPAENEDPDKAVVDLHRSPPKTKDPD"
     gene            7685..8977
                     /locus_tag="MEXAM1_RS25400"
                     /old_locus_tag="MexAM1_META2p0009"
     CDS             7685..8977
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMO-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092:hypothetical
                     protein (Score: 321.4; E-value: 2e-97)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003598536.1"
                     /locus_tag="MEXAM1_RS25400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MexAM1_META2p0009"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_003598536.1"
                     /sec_met_domain="FMO-like (E-value: 8.9e-51, bitscore:
                     162.3, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.3e-12, bitscore:
                     36.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQERIGIIGAGASGIGIAKALRREGIEFEMLESTSRVGGNWQPD
                     GPASKMYRSAHLISSKRNTQFSDYPMPDDYPHYPHHSLMHDYLQSVVASTDVQRSIRFG
                     TTVTSARHDGSGWRLRFKEGGDAFYGTLIVCSGLLRRPIIPFYPGRFDGETIHAVEYRS
                     SSMLEGKRVLVVGGGNSGCDIAVDAVHGAAKVFHSTRRGYHYMPKFIAGRPTQEWLMDI
                     APEFSDPDAYWEHVSQTFRLAGFDGRDFGLPPPDHGIQSAHPILNSQILFHIGHGDISP
                     VGDIVKMSGRQIEFSDGTREEVDLIIWATGYDPDLPFFNKSDFDAVEDLNSAFLKVASR
                     RYDDLLYVGYLNTPSGLGNVGNVLGSFTAAYLQGRAGATAGWQKFQLLKRENAPVDLGQ
                     ERFMRTKRHSHEVDLWKFIKTMNFLSAKLRQ"
     gene            9027..14051
                     /locus_tag="MEXAM1_RS25405"
                     /old_locus_tag="MexAM1_META2p0010"
     CDS             9027..14051
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]; GO:0008483 - transaminase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_PP (49-119). E-value: 2.9e-13.
                     Score: 41.9. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25405_PKS_PP.1"
                     /NRPS_PKS="Domain: Aminotran_3 (840-1096). E-value:
                     1.5e-20. Score: 65.3. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25405_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMO-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 119.4;
                     E-value: 3.1e-36)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003598537.1"
                     /locus_tag="MEXAM1_RS25405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MexAM1_META2p0010"
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_003598537.1"
                     /sec_met_domain="PP-binding (E-value: 1.1e-13, bitscore:
                     41.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 9.8e-14, bitscore: 41.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1e-11, bitscore:
                     35.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_3 (E-value: 4.1e-23, bitscore:
                     71.2, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.7e-11, bitscore:
                     31.7, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FMO-like (E-value: 4.4e-68, bitscore:
                     219.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHFEDHRVGSDRLAADGEISADEALSMLDAIGTGQSTPTGADDL
                     KARIVQDLGLLIASVLKLQLEDLSPGRTWMDYGLDSIASTELATLFTEKYGLSLPPTIF
                     FEFQNIDSFADYLLSSHRVQLEKKYSVHLPRLVIAKAGSATPTIPPKHVRPSPTPEGGP
                     SSIEALWGDAGRSMPSATRGLAASPVSEPVEVRSPLDRVIAFPKSTDREPSVEDLRRCR
                     PLVEAAELHGFQRRGGGKLECATFGRGRPLLLLGGLVMHYSVMWQLQLEQWGAEHRLVM
                     FHMPGCGGASLYDGVTLDSLVDDVAQVLEELGIAEAVPVLGYSFGGVLAQAFALRHPAR
                     CSALAVCVSTSSADGVGDFRSLMQELQKSPRFMEVNRGWPMAALPTYGRVVEGFDFRSA
                     LGRLGMPTLVVSAEDDRYMTPAYSSALSARIPNARLLEFRDAGHLVGFTHHDEFNRAVL
                     DFLAEVHGRRPVHGAEDPSNPTICSDATDETLQLLSEYVRSGEQGHTIMLSPAVAQAAL
                     LLDAGLGASKREKRSTRSYFLTSGVEAVDSAFRFARHLARNRSGSSRGGILLVDRTDQV
                     IRHFDPLGMGTSGALVPGIQSVSDLDAASDILAGSDAREIVALAYVADPRDTIEDAGRF
                     LAMAKAASLTSILIDRNDTGTLPSDWLSVRMPERTDIVVLGEALGGFQVPAAAMVVGDN
                     VANPWLMTPNEGYVRHPMANLGFTARVVLEHLAKHLPLDAARVREFRRIASDPEANYEA
                     HSRYGNSGYARVARMHGFDARFYEGRGARSRMVLANRPPRDIVDCLSNVGTCPRGINPL
                     DIATEVAGAHSRERDYNADLRSFLHATTGFEVFLQAPSYVAAIDTALALGLAGSGGRTK
                     IVAFTGGAAFSLASAAVARDALFDSFRTPFQPVYARTVFIDPDAPEARAKLEEELAGGD
                     VALVWLETIQVEGNATRPLPSDLVETVEGMRGSGGYLVAVDETQTALWTGHMIHSARTV
                     REPDIAVLGTALTDGVLPIGGVLTRGTLLGAAYKAHPSWARAAERMHVCQLSAHVALHS
                     LEDIQARGLLELARTNGIYLRTALEALQSRHPIVADVRGEGLLLTIELNLDAQPQFVRQ
                     SFGYLLWGWMLRDANGGVATVVCPLHNNCLRLAPPLTITREEIDAIVAGFDRALTVGIP
                     GVLRDCATYCEERGDMRTATYIGGLVSDLPAAISSSLERKTKSEARTKRGGPGYTSVCI
                     VGAGVAGISMAKALKDKNILFECYEARDQLGGIWAYDEEGLQTSTWANLNMNTPKGHYQ
                     FADMPMPSHYPDYPNRQQVKDYLEAYVDKNGLRDNIHLGCRVSKATRREDGKWDVVLEN
                     GSRRLFDALAVANGHHNEPTVPDFIKNGTFTGTVTHSQKYRTRHEYRGQRVMVVGIGNS
                     GSQIAVDVSHDASMTYLAVRRGVYVLPHYLLGMRIDKALGPLNSWWVKKILRYPLHEML
                     MTSTYNLFIARHKNIGMPRPDHWMMSCLPTMSENLVNRIGDGKLKIVSDVERAEGKTLH
                     LKDGTSLEVDAIICSTGYKTTFPFLEREIVDTPDNRVQLYKRVFHPEVDNLVFIGLFQA
                     ITWGFLDIMERQGQLAAQYFAGEYMLPSVADQKAEIERERARIEREYVKSLRNQYYLHG
                     PTYMREMKLEMRRGQKRMRKAKAPRSFFFGATASQQ"
     aSDomain        9174..9383
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25405_PKS_PP.1"
                     /evalue="2.90E-13"
                     /label="MEXAM1_RS25405_PKS_PP.1"
                     /locus_tag="MEXAM1_RS25405"
                     /protein_end="119"
                     /protein_start="49"
                     /score="41.9"
                     /tool="antismash"
                     /translation="VQDLGLLIASVLKLQLEDLSPGRTWMDYGLDSIASTELATLFTEK
                     YGLSLPPTIFFEFQNIDSFADYLLS"
     aSModule        9174..12314
                     /domains="nrpspksdomains_MEXAM1_RS25405_PKS_PP.1"
                     /domains="nrpspksdomains_MEXAM1_RS25405_Aminotran_3.1"
                     /incomplete
                     /locus_tags="MEXAM1_RS25405"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       9987..10028
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25405_0001"
                     /evalue="1.10E-04"
                     /label="NRPS-te1"
                     /locus_tag="MEXAM1_RS25405"
                     /protein_end="334"
                     /protein_start="320"
                     /score="14.8"
                     /tool="antismash"
                     /translation="LGYSFGGVLAQAFA"
     aSDomain        11547..12314
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25405_Aminotran_3.1"
                     /evalue="1.50E-20"
                     /label="MEXAM1_RS25405_Aminotran_3.1"
                     /locus_tag="MEXAM1_RS25405"
                     /protein_end="1096"
                     /protein_start="840"
                     /score="65.3"
                     /tool="antismash"
                     /translation="GFEVFLQAPSYVAAIDTALALGLAGSGGRTKIVAFTGGAAFSLAS
                     AAVARDALFDSFRTPFQPVYARTVFIDPDAPEARAKLEEELAGGDVALVWLETIQVEGN
                     ATRPLPSDLVETVEGMRGSGGYLVAVDETQTALWTGHMIHSARTVREPDIAVLGTALTD
                     GVLPIGGVLTRGTLLGAAYKAHPSWARAAERMHVCQLSAHVALHSLEDIQARGLLELAR
                     TNGIYLRTALEALQSRHPIVADVRGEGLLLTIEL"
     gene            14081..17062
                     /locus_tag="MEXAM1_RS25410"
                     /old_locus_tag="MexAM1_META2p0011"
     CDS             14081..17062
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (14-441). E-value:
                     2.9e-164. Score: 538.8. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25410_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_DHt (587-713). E-value: 3e-10.
                     Score: 32.2. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25410_PKS_DHt.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) tra_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 245.2; E-value:
                     2.1e-74)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003598538.1"
                     /locus_tag="MEXAM1_RS25410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MexAM1_META2p0011"
                     /product="polyketide synthase"
                     /protein_id="WP_012753526.1"
                     /sec_met_domain="tra_KS (E-value: 1.7e-165, bitscore:
                     540.4, seeds: 44, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTAAAITSESAPPVAIVGMHGRFPGAADTPAFWSNLVAGKDVVG
                     EIPGDRWNWRRLHGEKSAEGETSYSRWGGFTEHVDCFDAGFFGILPREAESMDPQQRLF
                     LQTAHSAFEDAGFAARDLAGRKVGVFVGVGNADYPVLMRGDRVPVDAYRGTGMALTAIP
                     NRVSFQFDLRGPSSAVDTACSGSLVALHRAVASLRDGECELALVGGVNLLLGPELYVAF
                     SKAEMLSPTGRCRTFDAGADGYVRGEGVAALVLRPIAAALADGDYVYGLIRGSAENHGG
                     RAHSFTAPNPDAQAEVIRDAWTRAGLPLGNAAFIEAHGTGTPLGDPIEIDGIKKALALS
                     GGSDRPNGVLPIYISSLKSHIGHLEAAAGIAAVIKAVLSLQRSELPGNQHFEHLNPQIE
                     IGNSPLAIPEKNVPLQTRGVPLCAGVSSFGFGGVNAHVVLEGVASAAQRDADGEGRPFL
                     ILLSARDESGLRARAAQLLDVVQYAEGTARQRRLELELYDALAIPRTPDAAPAGLAANA
                     VSPTKLTRALEQLSTTAGRGLTIADVRDCVTVEEVAERIARRPSSFALRDLSRLISGTA
                     LPESAKRSISVPSIARSLMLGREPMSERLAFVVRSLSDLIKRLESFLADADGEWKRFTL
                     RGRGEKLVPPVTSSGHPSEHHLMRWAEYWGLVKAPQTPWAGIYPDFPLPAKTPLPAYPF
                     ELKRIWFRSTAPAPAAESEDQGRKSRSNVMHLHEGGLEAREGRRLLPISVAWRECWGAS
                     TVGLPSSLVALPVLAEHLERSGSRAGAADRIGLGRPCDLQAGATARKSGDGEKAVIHCI
                     AEGPTTGALLEARAASVAPGFIPQPSAECTGTVDGSEFYRMLERAGFQPDARYRCVRRV
                     AIGRGHLGFEVDLHRTAAEDGRFWTALISTVVLGIGWLLDPALSPSGFGMIWRIGLLRF
                     DADAYDHVVRIDIAQTEDGTISVWARNDRSEPALGLTDVLTRNFSLAPVGRTELRSRAA
                     GAGR"
     aSDomain        14123..15403
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25410_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="2.90E-164"
                     /label="MEXAM1_RS25410_PKS_KS.1"
                     /locus_tag="MEXAM1_RS25410"
                     /protein_end="441"
                     /protein_start="14"
                     /score="538.8"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="VAIVGMHGRFPGAADTPAFWSNLVAGKDVVGEIPGDRWNWRRLHG
                     EKSAEGETSYSRWGGFTEHVDCFDAGFFGILPREAESMDPQQRLFLQTAHSAFEDAGFA
                     ARDLAGRKVGVFVGVGNADYPVLMRGDRVPVDAYRGTGMALTAIPNRVSFQFDLRGPSS
                     AVDTACSGSLVALHRAVASLRDGECELALVGGVNLLLGPELYVAFSKAEMLSPTGRCRT
                     FDAGADGYVRGEGVAALVLRPIAAALADGDYVYGLIRGSAENHGGRAHSFTAPNPDAQA
                     EVIRDAWTRAGLPLGNAAFIEAHGTGTPLGDPIEIDGIKKALALSGGSDRPNGVLPIYI
                     SSLKSHIGHLEAAAGIAAVIKAVLSLQRSELPGNQHFEHLNPQIEIGNSPLAIPEKNVP
                     LQTRGVPLCAGVSSFGFGGVNAHVVLEG"
     aSModule        14123..16219
                     /domains="nrpspksdomains_MEXAM1_RS25410_PKS_KS.1"
                     /domains="nrpspksdomains_MEXAM1_RS25410_PKS_DHt.1"
                     /incomplete
                     /locus_tags="MEXAM1_RS25410"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       14600..14647
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25410_0001"
                     /evalue="1.70E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="MEXAM1_RS25410"
                     /protein_end="189"
                     /protein_start="173"
                     /score="17.0"
                     /tool="antismash"
                     /translation="GPSSAVDTACSGSLVA"
     CDS_motif       14789..14827
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25410_0002"
                     /evalue="1.00E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="MEXAM1_RS25410"
                     /protein_end="249"
                     /protein_start="236"
                     /score="15.2"
                     /tool="antismash"
                     /translation="FDAGADGYVRGEG"
     CDS_motif       15020..15067
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25410_0003"
                     /evalue="1.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="MEXAM1_RS25410"
                     /protein_end="329"
                     /protein_start="313"
                     /score="13.6"
                     /tool="antismash"
                     /translation="FIEAHGTGTPLGDPIE"
     CDS_motif       15146..15187
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25410_0004"
                     /evalue="4.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="MEXAM1_RS25410"
                     /protein_end="369"
                     /protein_start="355"
                     /score="9.9"
                     /tool="antismash"
                     /translation="SLKSHIGHLEAAAG"
     aSDomain        15842..16219
                     /aSDomain="PKS_DHt"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25410_PKS_DHt.1"
                     /evalue="3.00E-10"
                     /label="MEXAM1_RS25410_PKS_DHt.1"
                     /locus_tag="MEXAM1_RS25410"
                     /protein_end="713"
                     /protein_start="587"
                     /score="32.2"
                     /tool="antismash"
                     /translation="PSIARSLMLGREPMSERLAFVVRSLSDLIKRLESFLADADGEWKR
                     FTLRGRGEKLVPPVTSSGHPSEHHLMRWAEYWGLVKAPQTPWAGIYPDFPLPAKTPLPA
                     YPFELKRIWFRSTAPAPAAESE"
     CDS_motif       15944..15964
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25410_0005"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="MEXAM1_RS25410"
                     /protein_end="628"
                     /protein_start="621"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="FLADADG"
     gene            17059..19074
                     /locus_tag="MEXAM1_RS25415"
                     /old_locus_tag="MexAM1_META2p0012"
     CDS             17059..19074
                     /NRPS_PKS="Domain: PKS_AT (4-279). E-value: 1.6e-56. Score:
                     183.7. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25415_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 345.6; E-value: 1e-104)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.2"
                     /locus_tag="MEXAM1_RS25415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MexAM1_META2p0012"
                     /product="acyltransferase domain-containing protein"
                     /protein_id="WP_003598540.1"
                     /sec_met_domain="PKS_AT (E-value: 3.2e-57, bitscore: 183.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVLFPGQGIQRKGMGRELFGRYPDLVAAADRILGYSLEELCLD
                     DPRDELSRTAFTQPAIFVVSMLAYYDRRNAGLQEPDFLAGHSVGEIGALAAAGAFDFET
                     GLILVQRRAALMGQADGGGLVAVVGPPSEVVASLLSAAGLQGLSVANFNTPTQTVVGGP
                     VEQLETFLRQCSDQGHRAVRLRVSGAFHTAAMQEASDRFRGFLAGIGIGRPRIPVALNV
                     TGRLHSGEDLRDVLAAQIASPVLWSRCVEALAAAGADEFEEVPSPGVLTKMVAEIRSCW
                     SAGPLARLADSLAPPSFREVFGCRPLFGGGLGRGMAGVDLVRALASAGAFGFLDTEDLP
                     LALVEDGLKSLASDPAVGRRYGACLSPSPLDPGREDVLIDLFIRSNVPAIEMRGFDQPS
                     GAAARYRNGSAGQVLARVGCRAAADRFLEPAAGDGKPFAAALCVDMGFWRSAGGGTLDL
                     LRELLAMRAEGRNSGRPAGRVLIGVLGVCGSRDGAATAFSMGCDFIHSGSTMVFAEEAR
                     LQDGARLAIYGGAEGVVETLPDWWLPELASRSMFWLECGATSQEIRSLQDLYLRGSAGM
                     AEIYDVISQLGIELRHRIGKPETHEARGTLREAAAVVFGSRTVPCDPAFLRFREWSGLR
                     GSDPSQSLSASTIADLLIPGMPAGEIQAAKGDRPWN"
     CDS_motif       17071..17118
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25415_0001"
                     /evalue="1.70E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="MEXAM1_RS25415"
                     /protein_end="20"
                     /protein_start="4"
                     /score="20.2"
                     /tool="antismash"
                     /translation="LFPGQGIQRKGMGREL"
     aSDomain        17071..17895
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25415_PKS_AT.1"
                     /evalue="1.60E-56"
                     /label="MEXAM1_RS25415_PKS_AT.1"
                     /locus_tag="MEXAM1_RS25415"
                     /protein_end="279"
                     /protein_start="4"
                     /score="183.7"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGQGIQRKGMGRELFGRYPDLVAAADRILGYSLEELCLDDPRD
                     ELSRTAFTQPAIFVVSMLAYYDRRNAGLQEPDFLAGHSVGEIGALAAAGAFDFETGLIL
                     VQRRAALMGQADGGGLVAVVGPPSEVVASLLSAAGLQGLSVANFNTPTQTVVGGPVEQL
                     ETFLRQCSDQGHRAVRLRVSGAFHTAAMQEASDRFRGFLAGIGIGRPRIPVALNVTGRL
                     HSGEDLRDVLAAQIASPVLWSRCVEALAAAGADEFEEVPSPGVLTKMVAEIRS"
     CDS_motif       17293..17406
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25415_0002"
                     /evalue="3.00E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="MEXAM1_RS25415"
                     /protein_end="116"
                     /protein_start="78"
                     /score="41.8"
                     /tool="antismash"
                     /translation="EPDFLAGHSVGEIGALAAAGAFDFETGLILVQRRAALM"
     gene            19065..19328
                     /locus_tag="MEXAM1_RS25420"
                     /old_locus_tag="MexAM1_META2p0013"
     CDS             19065..19328
                     /NRPS_PKS="Domain: PP-binding (11-77). E-value: 2.8e-17.
                     Score: 54.9. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25420_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047:phosphopantetheine-binding domain-containing
                     protein (Score: 65.1; E-value: 8.8e-20)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003598542.1"
                     /locus_tag="MEXAM1_RS25420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MexAM1_META2p0013"
                     /product="acyl carrier protein"
                     /protein_id="WP_003598542.1"
                     /sec_met_domain="PP-binding (E-value: 5.5e-18, bitscore:
                     54.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTDADRIEEYIAGFISKELGIPESDVDYDLNFGAFGLSSMSGM
                     KLVGRLEEELQTKIKPSMLFENPTISKLAEAIAARGSTSNAA"
     aSDomain        19098..19295
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25420_PP-binding.1"
                     /evalue="2.80E-17"
                     /label="MEXAM1_RS25420_PP-binding.1"
                     /locus_tag="MEXAM1_RS25420"
                     /protein_end="77"
                     /protein_start="11"
                     /score="54.9"
                     /tool="antismash"
                     /translation="YIAGFISKELGIPESDVDYDLNFGAFGLSSMSGMKLVGRLEEELQ
                     TKIKPSMLFENPTISKLAEAI"
     gene            19425..21200
                     /locus_tag="MEXAM1_RS25425"
                     /old_locus_tag="MexAM1_META2p0014"
     CDS             19425..21200
                     /NRPS_PKS="Domain: CAL_domain (45-483). E-value: 4.7e-99.
                     Score: 323.6. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25425_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     335.2; E-value: 9.3e-102)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003598544.1"
                     /locus_tag="MEXAM1_RS25425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MexAM1_META2p0014"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_244426980.1"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-83, bitscore:
                     269.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDFELFSAAGSLPVHDVLAIRTWLTPDKTLFTFLDDEGEECNRL
                     TYLDLWRRCRAVGASLAAVSDPGDRIMLFYPPGLDFISAFIGCLMVGRVAVPSNLPARR
                     RVDRSVNIVTDCGAKVAMGPSDQVPEFRRSFEGTKAETLQWIATDTLPLEDGPPCLPEQ
                     PSSVDMGAVAYLQYTSGSTSNPKGVMITFGNVTTNCRMIRDTLRLNQDSTMVFWQPHHH
                     DMGLICAVLLPVVIGNHTVLMTPATFVRQPMLWIQIISRYKAEVAGGPNFAFDMATERY
                     APAKMEGVDLSNWRLALNGSDIVRPSTLDRFAERFGPHGYRPETFLICYGMAEAVLFLS
                     AGPVGKKPRYAAVDIEELEQHRRVQLPTDPSRSRLLVGCGEPSWEVEAIAVEPETRRKL
                     PVGEVGEIWIHSATVGIGYWENPEESDRTFRAHTEEDAGKNYLRTGDLGFIHPEDRQVY
                     ICGRIKDLIISEGRNVHPEDIEYTISEALAARGESKTISSVVFNVEFNDRQLIVAAVEV
                     DRSLKRALLEKGAEIERAIRQAVAADHGVTLHRLLFIPPSSMCKTTSGKVQRGLMRQIY
                     VNGALSALEPVGAAA"
     aSDomain        19560..20873
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25425_CAL_domain.1"
                     /evalue="4.70E-99"
                     /label="MEXAM1_RS25425_CAL_domain.1"
                     /locus_tag="MEXAM1_RS25425"
                     /protein_end="483"
                     /protein_start="45"
                     /score="323.6"
                     /specificity="Minowa: Acetyl-CoA"
                     /tool="antismash"
                     /translation="TYLDLWRRCRAVGASLAAVSDPGDRIMLFYPPGLDFISAFIGCLM
                     VGRVAVPSNLPARRRVDRSVNIVTDCGAKVAMGPSDQVPEFRRSFEGTKAETLQWIATD
                     TLPLEDGPPCLPEQPSSVDMGAVAYLQYTSGSTSNPKGVMITFGNVTTNCRMIRDTLRL
                     NQDSTMVFWQPHHHDMGLICAVLLPVVIGNHTVLMTPATFVRQPMLWIQIISRYKAEVA
                     GGPNFAFDMATERYAPAKMEGVDLSNWRLALNGSDIVRPSTLDRFAERFGPHGYRPETF
                     LICYGMAEAVLFLSAGPVGKKPRYAAVDIEELEQHRRVQLPTDPSRSRLLVGCGEPSWE
                     VEAIAVEPETRRKLPVGEVGEIWIHSATVGIGYWENPEESDRTFRAHTEEDAGKNYLRT
                     GDLGFIHPEDRQVYICGRIKDLIISEGRNVHPEDIEYTI"
     CDS_motif       19941..19997
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25425_0001"
                     /evalue="4.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="MEXAM1_RS25425"
                     /protein_end="191"
                     /protein_start="172"
                     /score="25.3"
                     /tool="antismash"
                     /translation="AYLQYTSGSTSNPKGVMIT"
     CDS_motif       20622..20711
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25425_0002"
                     /evalue="2.30E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="MEXAM1_RS25425"
                     /protein_end="429"
                     /protein_start="399"
                     /score="29.6"
                     /tool="antismash"
                     /translation="PVGEVGEIWIHSATVGIGYWENPEESDRTF"
     gene            21215..21997
                     /locus_tag="MEXAM1_RS25430"
                     /old_locus_tag="MexAM1_META2p0015"
     CDS             21215..21997
                     /NRPS_PKS="Domain: Thioesterase (18-238). E-value: 1.6e-37.
                     Score: 121.9. Matches aSDomain:
                     nrpspksdomains_MEXAM1_RS25430_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 203.4; E-value: 4.9e-62)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003598546.1"
                     /locus_tag="MEXAM1_RS25430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MexAM1_META2p0015"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_275450678.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.9e-13, bitscore:
                     39.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGRSWAVLGEDAPEQPCLVCFHFAGGSAQSFLPWRKHVVGRYNL
                     LAAELPGRGRRYGEAFASSVDEAAAQFAEEALHLPRNPLIFVGHSLGALLAYETAYAMR
                     ERGGRQPIGLVAAGRQSPDVDQHGRNLPDASMSAIRKYLQELSGTPESILRDDAYMTMM
                     RPILQADFDLLRSYRFRPRTPLQIPVHVVGAIHDHAVKFESLLGWSRLSVGEVSLSLID
                     GGHFAPIEQPASILDKADRIAGGVASTSIGEQFAPACA"
     aSDomain        21269..21928
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MEXAM1_RS25430_Thioesterase.1"
                     /evalue="1.60E-37"
                     /label="MEXAM1_RS25430_Thioesterase.1"
                     /locus_tag="MEXAM1_RS25430"
                     /protein_end="238"
                     /protein_start="18"
                     /score="121.9"
                     /tool="antismash"
                     /translation="LVCFHFAGGSAQSFLPWRKHVVGRYNLLAAELPGRGRRYGEAFAS
                     SVDEAAAQFAEEALHLPRNPLIFVGHSLGALLAYETAYAMRERGGRQPIGLVAAGRQSP
                     DVDQHGRNLPDASMSAIRKYLQELSGTPESILRDDAYMTMMRPILQADFDLLRSYRFRP
                     RTPLQIPVHVVGAIHDHAVKFESLLGWSRLSVGEVSLSLIDGGHFAPIEQPASILDK"
     CDS_motif       21452..21517
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MEXAM1_RS25430_0001"
                     /evalue="2.70E-07"
                     /label="NRPS-te1"
                     /locus_tag="MEXAM1_RS25430"
                     /protein_end="101"
                     /protein_start="79"
                     /score="23.1"
                     /tool="antismash"
                     /translation="PRNPLIFVGHSLGALLAYETAY"
     gene            22108..23211
                     /locus_tag="MEXAM1_RS35190"
     CDS             22108..23211
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022694.2"
                     /locus_tag="MEXAM1_RS35190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3047 domain-containing protein"
                     /protein_id="WP_244426982.1"
                     /transl_table=11
                     /translation="MTASQSLTHEADPASIVAGLKASFETAASAINGSTVLKLAADKED
                     WVDTGVFVKEGQEVSLLSEGVIWLSREFDIQVKGNAALWYRVGNGTIEKSAGRTTTFRA
                     DRDGPLQLACRLAGHWLDDTGRLDPDVPPMPMEGALTVGVAAWETDAKEGLERLAGSDD
                     TDLAQAELERLRSSRPLPKGWDHLWRVGRTDIFCESVTEGGPVLSCNCTADSGIIKYPV
                     DVALDRSTTLSWEWLVRALPSEVPENTLVTHDYLSIAVEFENGQDLTYFWSSTLPLETS
                     FRCPIPGWEKRETHIVVRTGQEQVGTWVADSRGVLADYEAAVGVEHPGRVVGVWIIALS
                     PFQRRNGRAEYRKIKLSSDTETVEVGP"
     gene            23386..25209
                     /locus_tag="MEXAM1_RS25440"
                     /old_locus_tag="MexAM1_META2p0017"
     CDS             23386..25209
                     /GO_function="GO:0020037 - heme binding [Evidence IEA];
                     GO:0005506 - iron ion binding [Evidence IEA]; GO:0016705 -
                     oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 331.1; E-value:
                     1.9e-100)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003598550.1"
                     /locus_tag="MEXAM1_RS25440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MexAM1_META2p0017"
                     /product="cytochrome P450"
                     /protein_id="WP_003598550.1"
                     /sec_met_domain="p450 (E-value: 5.5e-78, bitscore: 252.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIKVSQVSGLELNKPTHIEVEGIDLVLLGTGSKISLFESRCPHQ
                     GAFLHEGAVRNGALVCRAHGWAFDADTGVCRGKQGIALTSIPLRIEGDDILADAEAVRA
                     LADRRKTEGRSSETVASVIQSQRTINDLPGPAGLPVLGNAHQINLEQLHVTMENWHEQY
                     GSFFKFRILRQNAIAVAHPHLIRMVLRERPHNFRRISSIESVFQEMHAQGLFSVEKEEW
                     RYQRRIVAQALNARQIRLFFPKMQQITERLMRRWSRASEDGRVVDVQEDLMRYTVDVTS
                     NLSFNYDMNTVEKEGDVIQDHLEHVFPMISRRVNSAVPYWRYFKFQRDRDLDKALVALK
                     GIIDDIIDKSRDRLKQNGGNVEAGNLVEAMLQLQETEGAITNDAIFGNVFSLLIAGEDT
                     TANTMVWILHFLSSRPEVFKRMQEEADEVLGGSDVLPDLETANRLIYHDAVINEALRLK
                     PVASIWPMEACSDVVMDGVAVPAGTPVFLLTRIPTLVDENGVPAPEFDPERWLRKDAST
                     THFDNVMVPFGAGPRLCPGRSLSLLEIRAVMSMVSRRFELELPTDGPSVGERFAFTLIP
                     TNVRLRFKERNKYPAGPQFIAPTAESVRLGA"
ORIGIN
        1 atggagatta aggactgtat tgctttcgtg accggcgcca atgggggcat cggaagcgcg
       61 ctggttagcg agcttctcag gcggggcgtg agacgggtat acgcggcttc gagatcacca
      121 cgcgccgaaa cacctggaac agcggaagcg ccgggccgcc ttccgttgct gctcgatgtg
      181 gttgactcct ccagcgtttc ctcagcggca cgactggctc acgatgtaac attgctgttc
      241 aacaatgccg gatcaatgac gcgaggttcg ctgctcaaga caaagctcgc ggacgtgcgc
      301 ggcgatatgg aagctaattt cttcggcaca taccaaatgg tccgcgcttt cgccggcgtc
      361 atcgaacgca acggcggcgg aggcatcgtc aacattctat cagtttcggc gtgggccagt
      421 tcgcccgatg cagctggcta cagcgcgtca aaggcggcag cgcattccct aacgcagtct
      481 cttcgagcgg aacttgcgcc ccgaggcgtc gctgtgctcg ccgcatatcc tggtccggtc
      541 aacaccccca tgacccgtga tctcgagatc ccaaaagcag atccaaacga agttgcccgc
      601 tcgattgtcg acggagtcga gaatgaccaa gaggatattg ttccagaccg gatgtctagg
      661 caggccgcag atgcatggcg gagagaccca aaagtacttg aacgccagtt tgcgtcatta
      721 tactcagcgg gcactatgta gagctacgta atcgcgcgaa acggcgtctc cgcccgacta
      781 cgaggacatg ctgccaatgc ggatgcatac tgctaactcc aaagacgcac acgaaacaaa
      841 acttctgctt cagcagtggg tatcctcgac gatctgcgac gtcactggac ttgatggtga
      901 ccgtgtcggc ccgaacgcgc ggctagaaga aatcggcctg gactcgctgg cgatcgtatc
      961 gtttggcact cgcctcgaac aacacatcca aggtttgcgt cggtctttta tcttcgactg
     1021 ccgaacggta ggcgagatct gcgaccatct gctgacgcac catcagccgg agttgggttt
     1081 cctgatctcg caggcggctt cgacgcccaa acagttgggg gagcgtccgt tccagaaggg
     1141 agcggaccca gcgtcggagg ctgaagactg gcccgaaatc gcactcgctg acttcgggac
     1201 cggtcgcgag acagctcaga gccatgagat gtcgccgagg gaatcgatcc agcgagatcg
     1261 gctgcacctt gataacgcag tcgccatcat cgggatgcag gggcagtttc caggggcggc
     1321 ttcgctggac gcattttggc agcagatcgc gtccggagcc gatttggtcg gcgagatccc
     1381 tgctgatcgc tggtccgtcg agggcttcta cgaggcgggc tccgcctcaa gaaagaccgg
     1441 gaagagctat tccaaatggg gggcttttct ccctggtgtc gacgaattcg acgcccagtt
     1501 tttcggcatc cctcctaggg atgcccgcct catggatccg caggaacgtc tgttccttga
     1561 gtgcgcctat cacgccatgg aggatgcagc tcttcttgga gcacggcagg aaagcctccg
     1621 tcgggacgtc ggcctcaaca tcggtgtctt cgttggaata accaccaaca cctacaacct
     1681 gcagggtccg agccattgga cggcgggagg tgtggaggtg cccacctcca tgccatggtc
     1741 gagcgcgaac agggtctcct atttcctcaa cctgtcgggt ccgagtgtcg cggtagatac
     1801 ggcctgttcg tcttcgcttg tcgcgctgca cctcgccgtc gaaagcgttg cggccggcga
     1861 gtgcgcagcc gcgatcgctg gcggagtgaa cctttatctt catccagcca aatacgttca
     1921 gctttgccag taccagatgt tgtcgccgac tggacgctgc cattctttcg gggccgatgc
     1981 cgacggcttc gtcccggggg aaggagttgc ggcggtcgta ctacgacctc tgcgcgacgc
     2041 gctgcagaat ggcgaccgca tcctcggcgt catacgcgga accgcggtca accacagcgg
     2101 gcggacgaac gggtacaccg tcccaggcgc cgcatcccaa gccgcactca tccgcaaggc
     2161 tctcgatcga gcagcgctca cgccagattc gattggttac atagaggctc atggaaccgg
     2221 caccaagctc ggcgacccga tcgagatcac tggcatctgc gatgctcttg gcgatagcgg
     2281 gcagccgtgc gcgatcgggt ctttgaaatc gaacatcggc catctcgagt cggcggcggg
     2341 gatcgcgggc atcgtgaagg tgctcctcca acttcggcac gaccggatcg ccccctcgat
     2401 ccactcaagg atcccgaacc cagatctcaa gctcgatggc ggacgatact tcgtcccgca
     2461 ggacctcgga ccatggccga aagcggcgtc ggatggccgt cggcgggccg gtatcagctc
     2521 cttcggtgcg ggcggcacat gtgcgcacgc gatcattgag gaagggccgg aggttccggt
     2581 cagctccgcc gtcgggccgc tcgtcttccc cctttcggcg cagtcgcctg aacagttgcg
     2641 gctccgggct caagacctcc tcaagtgggt tgggatggtg cagcccggcg acgagcgcac
     2701 gacgctgctt agactagcct acacgctgca gtgtggacga gcgacatacc gctaccgctt
     2761 cgcggcggct gcggcgagcg tacgcgatct ggctgcggcc gtcggcacct tcctggggga
     2821 agtggcgact gtagcgatcc taggctctca aggcgtcgag gattcggagg acgcgcggtt
     2881 ggccgcacgc tggtcgactg gagaagaggt cccctggccg acactgtggc agggccttcc
     2941 gtgccctgtc ggagggctac tctacccctt cctgcgcgat aggcatgctt tggctcctcc
     3001 tgagatccgg atggactctg ggcgcgaaag gccgggcgaa caggtcgaga tcgtggtgtc
     3061 tcacaccttc accggcgacg agagctatat ccgagaccat gtgatcggaa acagcccgat
     3121 actgcccggg actgcttatg tcggcctttg cagcgtgtta atcgggcagg ccggcggtga
     3181 tggctgggcg tttgacctcc aggatctcgc gtggtcgtcg ccctaccgct gggttcctac
     3241 cgctgccaag cagcttttgg tccgtggacg tcgcctcggc ccgagcttgt cgatcgaaat
     3301 tgcttcatcg tccgatgcac ggccccttca cttcaccgca cgcgctgatc tgggcggccg
     3361 ctctccaaca gcggatggcg aacctattcc tgcgattagg gagcggtgca cgcgatctgc
     3421 cgatgtcgcc ggcttctacg cgctcgccgc cgacttcggc atggtgttcg gagaaagttt
     3481 ccgctgcata gcgcgcgcga gcaagggccg cggcgaagca ctggtggagg ccaaacttcc
     3541 gacgggcagc aggcgtggcg gcactactgg tctgcccatc gacccagggc tcctcgacgc
     3601 agtctttcaa agcgccttct tctcggtcga ggaaggtttc gatggtccgc acgtcccggt
     3661 acgggccaag gccgtgcgca tccacggaga tcttggttcc aaccttgtga tccatgttcg
     3721 agcggtcgca caggcatcgg atggttttac tttcgactac cgactcttgg cgccctcggg
     3781 agcggtgatt ggggagatcg aggccctaac cttccagagg atcgaagctg tgcggggcag
     3841 gtcggcgctg gcggagcgga gcatcaacat cttcgagcct gtctggcttc ccgacgcagc
     3901 tgtcggattt ggagggcctc ctaccgcgtt gctcgccctc ggaagacaag accgcaacga
     3961 catccgtctg ggtctgaccg gcggaaccac acaggtccgc ctccgtcccg gcggagcatt
     4021 cgagatcgac ggaagccgca cggtcacgct cgatcccgag cgcaaggatc acctcgagca
     4081 tctctggaga acgttcaagg cagatggctc gctccccgcc gcagtggtag ccgacctgcg
     4141 gcaccaaccg gccgtctcgc cgcacgggtt ggagcggcac ctcggcctcg gccctttcat
     4201 cggcgcaatg gcgctcctca agagcgtcgt cgaggcgtac gctccgtcga aatcctgcag
     4261 gatgatcctg atctgtcagg gcccggctgc ttccgcggct gcggccatga tgcggtccgt
     4321 tcacatcgag gcgccgagcc tggacttcac cgtcctcgaa accgacggcg cggagcatcc
     4381 cgcttacctc gaccagtttg tcgacgcgga ggcgaagcgc acggctggag ggggcgtcag
     4441 acacgtccgc ttcatcggag gcacgcctct tgtccggcgc tacgcagcct tggacctgcc
     4501 cagtcgagat gccgacgtac ggtccggcga cgtcgtcctg atcacgggcg gactgggtgc
     4561 cgttgggctg cacatcgcga agcatctggc cctccaccgc ggggtacgga tcgcgttgct
     4621 cggacgctcg cgtccggccg agcacagccg ggcggctgta gcttccctcc gaatggcgga
     4681 aggcgattgc agctactggg aatgcgactg ctcctccggg gaggatctca cccaaaccct
     4741 tgccgacatc cggtcgcgaa tgggtcccct gacaggcatc ctgcactgcg ccggcgtgct
     4801 gaaggatgcg ttcttcacga ggcacaccga caccgagcgg tacgaggtcc tcaagtcgaa
     4861 agctctgtcc gcccggctcc tcgacgagat gacccggcag gatccgctgc gctggttcgt
     4921 actcagctcg gccctcgccg ccgtctgcgg caacatcgga cagagcgtct acggattgtc
     4981 gaatggctgg ctcgatgggt tcgccgagga acgcaactca ttgacagcgg ccggccgagc
     5041 ttcgggccgg accgtcgcag tcgcctggcc tctttggaac acccgcacgg ggatgcaggc
     5101 ctccgaacgc ttcttgcgca ggctccagga tgaggggctc gatcttctgg aacccgatga
     5161 aggagcgcgc ctcttcgcgg ccgcaacctg gagcgaccgc tctctcatcg ttcccatcaa
     5221 gggcgacgag gagcgatctt cccgcatcct cggcatcaag gacgcgggaa taccggccgg
     5281 caatacggat gacgccaccc tcgaaccgca gccaggtacc gccgacgcca acggcggcca
     5341 ggaggatcgg gttcttcggt atctgatcgg gacgctgtcc gatgtgaccg ggaccgcgcc
     5401 ggaacggatc gaacccgaca ctccgctcga agcattcggt ctggactcgc tgctcgtgct
     5461 ggaaatgagc gaccgcttgc aggagcgttt cccgcgcatt gccaggaccg ctctgttcga
     5521 ggcccgcaca cttcgagcgc tggcccgcct gctcatcgac gaacttccac tggacgtcgc
     5581 aaaacttgtc gcatccggcg tctccgtgga ggacgatgag cctctcgagg agccaacccg
     5641 tccagccgtc agcgccgccg ttgtcggcgg cagccctgag ccgggatcca cgacaggtaa
     5701 ccgtccggcc atcgccatcg ttggtctggc cggccgctat ccaggctctg cggacctatg
     5761 ggacttgtgg gaccatctgt gcgcagggag cgacttggtg accgaactgc cgccgcgcct
     5821 gagtgcgggc gaagagcgca acggcgtcta tgccaaatgg ggcagcttca tcgacgacgt
     5881 cgatacgttc gaccccctct tcttcggcat ctcgccacgg gatgccgaac gcatggaccc
     5941 gcaggagcgg atcttcctcc agacagcatg gcatgccgtc gaagacgccg gctacacgcc
     6001 tgaaggcttg tcaggtggct cggagcgcgg gacgcgccgt cgggtggctg tcatcgccgg
     6061 agtgatgtac ggcgaatacc agttcttcgg agcggccggg acgtcggagg ggggagctct
     6121 taccaactcc tcctacgcct ccattgcgaa ccgcgtctcc tactgtcttg atttcgacgg
     6181 cccctctttc gccgtcgaca gcatgtgctc gtcttcgctg accagcatgc acctggcgtg
     6241 cgaactgctc cagagcggtg gctgcgacat cgcactcgcc ggaggcgtta acatctctgt
     6301 acatccctac aagtacagga tgctctcgga actgaagttt gcggcgaccg acggtcgctg
     6361 ccgcagcttc ggggtaggtg gcgacggtta tgtgccggga gaaggttgcg gcgtcgtcgt
     6421 cctgcgcccg ctcgaagcag cccttgccgc aggcgaccac atctacggcg tgatccgggg
     6481 cagtgacatc gggcatggcg cgcggtcgtc cggctacacg gtaccgaatc ccgatgccca
     6541 ggccgaagta gtccgtcgcg ccttcgagag gagcggcgtg gatcctgccc ggctttccta
     6601 catcgaagcg cacggcacgg ggaccagcct cggagatccc atcgagatcc gcggcctcag
     6661 caaggctctg ggcagacagt tccccgaagg cggcacctgc gcgatcgggt ccatcaaggc
     6721 gaacatcggg catttggaat ccgcagcggg aatcgctggt ttgacgaagg tgctgctgca
     6781 gatgaagcac cgcagactgg taccctccat tcattccgct gaactcaatc ccttcatcga
     6841 cttcaaccag acccccttcc gggtgcagcg cgagcaggcc gaatggcagg cggttggcgg
     6901 gcggaggttg gcggcggtca gctccttcgg agccggaggg gcaaacgccc accttgtcgt
     6961 ggaaagctgg gaccacccga ctatgcctga ggtggcttcg agggagcctc ttgccctgct
     7021 gctctcatcg gcaaacgaag gtcaattgcg ggaggctgct cgtgttcttc tcaagcatct
     7081 cgaacgcgag ggggagatct ctccggacgc cgggcagtat tggatcggct cccagcactt
     7141 ctccctgcgg gacgtggcac tgacccttct ccacggcagg cgccacggcg atcaccgcct
     7201 cgcgatcata gcggctgact tcgatgagtt ccgccggaaa ctggcgttgt tcattcgcac
     7261 ggacagcaac gtaggagccg cgtcgggcga cttcgagcgt cttggcatcc ttattggagg
     7321 attgcagcct accgtccaag gcgacgccat ctacagggag gcccgtgcct gggtcgatgg
     7381 tgggccccca cccccgccgg aagcgccctg gaggcgcgtt ccgctgcccg gatacgtgtt
     7441 tcagcgcagg cgcttctggc tcggcagcct acctgcagag aacgaggatc cggacaaggc
     7501 ggtggtcgac ctgcacaggt caccgccgaa gaccaaagat ccggacctca ctccgagcgg
     7561 gatcatcgcg aaggtcaagg ccggggatat gacgcaggag accgccagag agctgctgct
     7621 tgccatgcgc tgagggcggc cgaccggaca tccagaaatc ccgtgggcac gaagtggatc
     7681 tgagatgagg caggaacgga tcggaatcat cggtgcaggt gccagcggaa taggcatcgc
     7741 aaaggcgttg cgccgcgaag ggatcgagtt cgagatgctc gagtcaacga gcagggtcgg
     7801 cggcaactgg cagccggacg gtccggcttc gaagatgtac agatctgcgc acttgatcag
     7861 ctccaagcgc aacactcagt tttcagacta cccaatgccg gatgattacc cacactatcc
     7921 gcaccactcc ttgatgcatg attatcttca atccgtcgtc gcctctacgg acgtccagag
     7981 gagcataagg ttcggtacca ccgtgacttc ggcgcgccac gacggtagcg gctggcgcct
     8041 tcgcttcaag gaagggggag acgccttcta tggcactttg atcgtctgct cgggtctcct
     8101 gcgcaggccc atcattcctt tctaccctgg ccggttcgac ggagagacga tccacgcggt
     8161 cgaataccgc tcgagcagca tgctcgaggg caagcgggtt ctagtggtcg gaggagggaa
     8221 ctctggctgt gacatcgcgg tcgacgccgt ccacggcgca gcaaaggtct tccactccac
     8281 gagacgtggc taccactaca tgccgaagtt catcgccggg cggcccacgc aggagtggct
     8341 gatggacatc gccccggagt tttccgaccc agacgcgtac tgggagcacg tttcccagac
     8401 cttccggctt gccggcttcg atggccgaga cttcggcctg ccgcctcctg atcacggcat
     8461 ccaatcggct catccgattt tgaactcgca gatcctgttt cacataggtc atggcgacat
     8521 ttccccagtc ggcgacatcg tcaagatgtc aggccgtcag atcgagttct cggacgggac
     8581 cagggaggaa gtagatctta tcatctgggc tacggggtac gatccggacc tacctttttt
     8641 caacaaatcc gattttgatg cggttgagga tctaaattcc gcgtttttaa aggttgcctc
     8701 acgcagatat gatgatctac tgtatgtcgg ctacctcaat acgccatccg gtctcggcaa
     8761 cgtcgggaac gtactcggca gctttacggc ggcctatctt cagggccgtg ccggggcgac
     8821 ggccggctgg caaaaattcc agctgctgaa gcgcgagaat gcgcctgtcg atcttgggca
     8881 ggagcggttc atgcgcacca aacgccactc tcacgaagtg gatctctgga agttcatcaa
     8941 gaccatgaac ttcctgtccg cgaagctccg gcaatgatcg tcttgactga cggcatcctt
     9001 ctcagctctt cacgaggttc gtagtcatga cgcacttcga ggaccaccgt gtcggttccg
     9061 accgcttggc cgcggacgga gagataagtg cggacgaggc gctgagcatg ctcgacgcca
     9121 tcggtacagg gcagtctacg ccgaccggcg cggacgatct caaggcccgc atcgttcaag
     9181 atctcggatt gctgatcgcg tccgtgctga agcttcagct ggaagatctg tcgcccggca
     9241 ggacatggat ggactacggt ctcgactcga tcgcttcgac cgagctggcg acgctgttca
     9301 ccgaaaagta cggactgtcg ctgccaccga ccatcttttt cgaattccag aacatcgact
     9361 cgtttgcaga ctatctcctt tccagtcatc gggtccaatt ggaaaaaaag tattcggtcc
     9421 accttcctcg tctcgtaatc gcgaaagcgg gctcggcgac gcctaccatc cccccgaaac
     9481 acgttcgccc ttcgcctacc ccagagggcg gcccttcctc gattgaggca ctctggggcg
     9541 atgctgggcg gtcgatgccg tccgctactc gcggactggc tgcgagcccg gtctcggaac
     9601 ccgttgaggt ccgcagtccg ctcgatcggg tgatcgcctt ccccaagtcg accgaccgcg
     9661 aaccttccgt ggaggatctg cgccgatgcc gccccctcgt ggaagccgcc gaactgcacg
     9721 gtttccagcg gcgcggcggc gggaagctgg aatgtgccac cttcggccga ggtcgcccgc
     9781 tcctgctgct cggcggcctc gtcatgcact acagcgtcat gtggcagctc cagctggaac
     9841 aatggggagc cgaacacagg ctcgtcatgt tccacatgcc gggatgcggc ggcgcctcgc
     9901 tgtacgatgg cgtcaccctc gacagtctcg ttgatgacgt cgcccaggtc ctcgaagagc
     9961 ttggcatcgc tgaagcggtt ccggtcctcg gctactcctt cgggggcgtc ctggcccagg
    10021 cgttcgctct ccggcatccc gcgcgttgct cggctttggc tgtctgcgtc agcacatcgt
    10081 cggcggatgg agtgggcgac ttccgcagcc tgatgcagga actgcagaag agcccccgct
    10141 tcatggaggt caaccgcggc tggccgatgg ccgcgcttcc gacctacggg cgcgtggttg
    10201 aaggcttcga tttcagaagc gctctcggac ggttgggaat gccgacgctg gtcgtctccg
    10261 cagaggacga ccggtacatg acgccggcct actcctccgc cttgtcggcg cgaattccga
    10321 acgcgcggct ccttgagttc cgtgatgccg ggcacctcgt cggcttcacc catcacgacg
    10381 agttcaaccg tgcggtgctc gactttctgg ccgaggtgca cggtagacgg ccggttcacg
    10441 gtgccgagga tccaagcaac cctaccatct gcagcgatgc tactgacgag accctacagc
    10501 tcctatcgga atacgtccgc tcgggcgagc agggtcatac gatcatgctt tcccccgcag
    10561 tcgcccaagc cgccttgctg ctcgatgcgg gattgggagc gtcgaagcgg gagaaaaggt
    10621 cgacgaggtc ctatttcctg acttcggggg tcgaggcggt cgactccgct ttcaggttcg
    10681 ctcggcacct cgcacgaaac cgttcgggca gcagccgagg cggcatcctc ctggtggatc
    10741 gcacggacca ggtcatccgg catttcgacc cactcggaat gggcacatcc ggggctcttg
    10801 ttcccggcat ccagtccgtc agcgacctcg acgccgccag cgacatcctc gcaggctcag
    10861 acgcgcgcga aatcgtggcg ctcgcctacg tggccgaccc gcgggacacg atcgaggatg
    10921 ccgggcgctt tctcgccatg gctaaggcag cctcactgac gagcatcctc attgatcgca
    10981 acgatacggg gacacttcct tccgactggc tctccgtccg aatgcccgaa cgaaccgaca
    11041 ttgtcgtgct cggcgaagct ctgggaggct tccaggtgcc ggcggcggcc atggtcgtgg
    11101 gcgataacgt ggccaatcct tggctgatga cgccgaacga gggctacgtc cgacatccga
    11161 tggccaatct cggcttcaca gcccgggtgg tgcttgagca tctcgcgaaa cacctgccgc
    11221 tggacgcagc cagggtccgg gagtttcgcc ggatcgcaag cgacccagaa gcaaactacg
    11281 aggcccacag cagatacggg aactcgggct atgcccgggt cgcgcggatg cacggcttcg
    11341 acgcccggtt ctacgaggga cgcggtgcca ggtcccggat ggtcctggcc aatcgtccgc
    11401 cgcgagacat cgtcgactgc ctttcgaacg tggggacctg cccacgcggc atcaatccgc
    11461 tcgatatcgc gaccgaggtg gccggcgctc actcccgcga gcgcgactac aatgcggacc
    11521 tgcgctcctt cctgcacgca acaaccggct tcgaagtctt tctgcaggct ccgagctatg
    11581 tcgcagcgat cgacaccgcg ctcgccctcg gccttgccgg atcgggcgga cggacgaaga
    11641 tcgtcgcatt taccggcgga gccgctttct cgctggcctc cgccgcggtc gcacgtgacg
    11701 cactgtttga cagttttcgg actcccttcc agcccgtcta cgcacgcacc gtcttcattg
    11761 atccggacgc ccccgaggcg cgagcgaagc tcgaggagga actcgccggc ggcgacgtag
    11821 ccctggtctg gttggagacg atccaggtcg aggggaacgc cacccgtcca ctcccgagtg
    11881 atctcgtcga gaccgtcgag ggcatgagag ggagtggagg gtatctggtt gcggtcgacg
    11941 agacgcagac ggcgctgtgg accggacata tgatccacag tgcacgaacg gtgcgtgagc
    12001 cggacatcgc ggtcctcggt acggctttga cggacggagt tctgccgatc ggcggcgtgc
    12061 ttacccgagg caccctcctt ggcgctgcct acaaggcaca tccgtcttgg gcccgtgcgg
    12121 cggaacggat gcacgtgtgt cagctctcgg cacacgtggc gctgcattcg ctggaggaca
    12181 tccaggccag aggactgttg gaactggcgc gcacgaacgg aatctacctc cgcacggctc
    12241 tcgaggcgct gcagagccgt caccccatcg tcgcggacgt ccgaggagag gggctgcttc
    12301 tcaccatcga gctgaatctc gacgcgcaac cgcaatttgt ccggcagagc ttcggctatc
    12361 tcctctgggg gtggatgttg agagatgcca acggcggcgt cgccaccgtc gtctgcccac
    12421 tgcacaacaa ctgccttcgg ctggcacctc cgctcaccat cactcgcgaa gaaatcgacg
    12481 cgatagtcgc cggcttcgac cgagctctta cggtcgggat cccaggcgtg ctgcgcgact
    12541 gcgcgaccta ttgcgaggaa agaggcgaca tgcgcacggc aacctacatc ggcggcctcg
    12601 tgtcggatct gcctgccgca atctcctcct ccctcgaacg caagacaaag agcgaggctc
    12661 gaacgaagcg cggcgggcct ggatacacgt ccgtctgcat cgtcggagcc ggcgtcgccg
    12721 gcatctcgat ggcgaaggcg ctcaaggaca agaacatcct gttcgaatgc tacgaagcga
    12781 gagatcagct cgggggaatc tgggcatacg acgaggaggg tctacagact tcgacctggg
    12841 cgaatttgaa catgaacacg ccaaaaggcc attaccagtt cgcggacatg cccatgccgt
    12901 ctcattatcc agattatccc aaccgacagc aggtgaagga ctatctggaa gcatacgtcg
    12961 acaagaatgg tctacgtgac aacattcacc ttggctgcag ggtctcgaag gcgacgcgga
    13021 gggaggacgg caagtgggac gtcgttcttg aaaacggcag caggaggctc ttcgatgctt
    13081 tggccgtcgc aaatggccat cacaacgagc cgacggttcc ggacttcatc aagaacggca
    13141 ccttcactgg tacggtcacg cattcccaga agtacaggac gaggcacgag taccgcgggc
    13201 agcgcgtcat ggtcgtcggt atcggcaaca gcggctctca gatcgctgtc gacgtcagcc
    13261 atgatgcttc gatgacatat ctcgctgtgc ggaggggcgt ctacgtgctg cctcactact
    13321 tactcggcat gcgcatcgac aaagctctgg ggccgctgaa ttcgtggtgg gtcaaaaaaa
    13381 tcctgcgcta cccgctgcac gaaatgctga tgacctcgac atacaacctc ttcatcgcac
    13441 ggcataaaaa catcggaatg ccgcgcccgg atcactggat gatgtcctgc cttccgacga
    13501 tgtctgagaa cctcgtcaac agaatagggg acggcaaact taaaatcgtc agcgacgtcg
    13561 aacgggcgga aggcaagacg ttgcacctga aggacgggac gagcctggag gttgacgcga
    13621 tcatctgctc gacgggctac aagacgacct tcccctttct ggaacgggag attgtggata
    13681 cacccgacaa tagggttcaa ctctacaagc gggtattcca tccggaagtc gacaatcttg
    13741 tcttcatcgg gttgttccag gcgatcacct ggggtttcct ggacatcatg gaacgacagg
    13801 gccagctcgc tgcacagtat ttcgcaggcg agtacatgtt gccatccgtc gcggatcaga
    13861 aagcggagat cgaacgcgag cgcgccagaa ttgaacgcga gtacgtgaag agccttcgga
    13921 accagtatta ccttcacgga ccgacatata tgcgcgagat gaaactggag atgcggcgcg
    13981 ggcaaaagcg catgcgcaag gcgaaagcgc ctcggagttt cttcttcggc gcgacggcca
    14041 gtcaacagtg acaattccgg caggtacaag ggcacgcacc atgaggactg ccgccgccat
    14101 tacgagcgaa agcgcgccac cggtcgccat cgtgggcatg catggccgct ttccgggcgc
    14161 ggctgatacg cccgctttct ggagcaacct tgtcgctgga aaggatgtcg tgggggaaat
    14221 tcccggcgac cgatggaact ggaggaggct gcatggggaa aagtcggcgg aaggtgaaac
    14281 ctcctacagc cgctggggcg gcttcacgga gcacgtcgac tgcttcgatg cgggcttttt
    14341 cgggatcttg ccgcgtgaag ccgagagtat ggatccgcag cagcgattgt tccttcagac
    14401 agcgcacagc gccttcgaag atgcaggctt cgctgcacga gatttggcgg gccgcaaggt
    14461 aggcgtcttc gtaggggtgg ggaatgcgga ttatccggtt ctgatgcgcg gcgatcgcgt
    14521 gccggtcgat gcatatcgag gcaccggcat ggcgctcacc gcgatcccga accgggtctc
    14581 gtttcagttc gatctgagag ggccgagcag cgcggtagac actgcctgct cgggatcgct
    14641 cgtcgctctt caccgggccg tcgcgtcgct cagggacggg gaatgcgagc tcgctctcgt
    14701 gggcggagtg aacctgcttc tcggtcccga gctctacgtc gccttctcca aagccgagat
    14761 gctgagtcca accggtcggt gccgaacctt cgatgccgga gcggatggct acgtgcgcgg
    14821 ggagggtgtg gcggcgctgg ttcttcgccc tattgcggct gcgctggccg atggcgacta
    14881 cgtgtacggc ctgatccgag gaagcgcgga gaaccacgga ggccgcgctc acagctttac
    14941 cgctccaaac cctgacgccc aggcagaagt aatcagggat gcctggacga gggccggcct
    15001 gccgctcgga aatgcggcgt tcatcgaggc tcacggcaca gggacgccgc tcggagatcc
    15061 tatcgagatc gacggcatca agaaggcgct tgccctctcc ggcggcagcg ataggcccaa
    15121 tggcgtcctt ccgatctaca tttcgagcct caagagccac atcgggcacc tcgaagccgc
    15181 cgccgggatc gcagccgtaa tcaaggcggt gctttcgttg cagcggtcgg agctaccggg
    15241 aaaccagcac ttcgagcacc tcaacccgca gatcgaaatc ggcaattcac ctctcgccat
    15301 tccggagaag aacgttcctc ttcaaacacg tggcgtcccg ctgtgtgcag gtgtgagctc
    15361 cttcggtttc ggcggagtga acgcacacgt cgtcctcgaa ggagttgcct cagccgcgca
    15421 acgggacgcc gacggagagg ggcgtccgtt cctgatcctg ttgtcggcca gggacgagtc
    15481 cggactacga gcgcgtgccg cacagctcct cgacgtcgtc cagtatgcag agggaacggc
    15541 ccggcaaagg cggcttgagc tcgaactcta cgacgcgctc gccatccctc ggaccccgga
    15601 tgccgcaccg gccggcctag cggccaatgc agtcagcccg acgaagctta cacgtgctct
    15661 tgagcagctg tcgacgactg cgggacgggg gttgaccatt gcagacgtcc gcgattgcgt
    15721 gacggtcgag gaagtagccg agcgcatcgc acggcgtccg tcgagcttcg cgcttaggga
    15781 cctgtcccgc ttgatcagcg ggaccgccct tccggagagt gcgaagcgct cgatcagcgt
    15841 accttcgatc gcccgatcgc tgatgctcgg cagagagccg atgtccgagc ggctcgcatt
    15901 cgtagttcgt agcctttcgg atctgatcaa gcgcctcgag agctttctcg ccgatgccga
    15961 cggcgagtgg aagcgattca cgctgcgcgg gagaggcgag aaacttgtcc cgccggtgac
    16021 gtcatccggt cacccatctg agcaccatct gatgcgatgg gcagagtact gggggctggt
    16081 caaagcccct caaactccgt gggccggcat ctatcccgac ttcccactgc cggcgaaaac
    16141 cccgctgccg gcctatcctt tcgaactgaa gcgcatctgg ttcagatcga ctgctccggc
    16201 tcctgccgct gaatccgaag atcaaggccg gaagagtcga tccaacgtca tgcatctgca
    16261 tgagggtggg ctcgaggcga gagagggaag gcgtctacta cccatttccg tcgcatggcg
    16321 ggagtgctgg ggcgcatcca cggtaggcct cccgtcttcg ctggtcgctc tgcccgttct
    16381 cgcagaacat ctggagcgga gcggctctcg ggcgggggcc gctgatcgga tcggactcgg
    16441 tcgaccctgc gaccttcagg ctggggctac ggcccgcaag tccggggacg gggagaaggc
    16501 tgtcatccac tgcatcgccg agggtccgac gaccggtgcc ctgctggaag caagggcggc
    16561 atccgtagct cccggcttca ttccccagcc ttcggccgaa tgcaccggta ccgttgacgg
    16621 ttccgagttc tacaggatgc ttgaacgagc gggctttcag cccgacgcac gctacagatg
    16681 cgtccgccgt gtcgccatcg gccgcggcca tctcggcttc gaggtcgacc tccacaggac
    16741 tgctgctgag gacgggcgct tctggacagc cctcatctcc acggtggtgt tggggatcgg
    16801 gtggctcttg gatcctgctc tgtcgccgag cggctttgga atgatctggc gtatcgggct
    16861 gctccgcttc gatgccgacg cctacgacca tgtcgtgcgc atcgatatcg ctcagaccga
    16921 ggacgggacg atatcggtct gggcacgcaa cgaccgcagc gaacctgccc tcggcttgac
    16981 ggatgtcctg actcgcaact tctcgctcgc gccggtgggc cgaacggagc tccgctcccg
    17041 agcggcggga gccggccgat gaaagccgta ctctttccag gccagggtat acagcggaag
    17101 ggaatgggcc gagaactctt cggtcgctac cccgaccttg tcgcggcagc tgaccgcatc
    17161 ctgggctaca gccttgagga actgtgcctg gatgaccctc gggacgagct ctcgcgtacg
    17221 gcattcaccc agcccgcgat cttcgtcgtg tcgatgctcg cctactacga ccggcggaac
    17281 gcgggactcc aggagccaga ctttctggcc ggacacagcg taggcgagat cggtgctctc
    17341 gcagccgcag gcgccttcga cttcgaaact ggtctgatcc tcgtacaacg ccgtgccgcc
    17401 ctgatggggc aagcagacgg aggggggctc gtcgcagtcg tcggtccacc cagtgaggtg
    17461 gtcgcttcgc tgctttccgc cgcgggcctg cagggtcttt ccgttgccaa cttcaacacg
    17521 cccacccaga ccgtggtggg cgggcctgtc gagcaactcg aaactttttt aagacagtgc
    17581 tcggatcagg ggcacagagc agtcagactc cgggtcagcg gcgcgttcca cacggctgct
    17641 atgcaggagg catcggacag gttccggggc ttccttgcag gcatcggcat cggacggccg
    17701 aggattccgg tggctctcaa cgtcacaggc cggttgcatt ccggcgagga cctccgagac
    17761 gtcctggcgg cgcagatcgc cagtcctgtg ctctggtcgc gctgcgtgga agcgctcgcg
    17821 gcggccgggg ccgacgagtt cgaggaggtt ccttccccag gcgttctcac gaagatggtg
    17881 gccgagatca gaagctgctg gtcggccggg cctctcgcac gcctcgccga ctcgcttgcg
    17941 ccaccctcct tccgcgaggt cttcggatgc cgccctcttt tcggcggcgg acttggacgc
    18001 ggcatggccg gcgtcgatct cgtgcgcgca ctcgcgtcgg caggggcgtt cgggttcctg
    18061 gatactgaag acttgcccct tgctttggtc gaggacggcc taaagtcgct cgcttccgat
    18121 cccgccgtcg ggcgacgcta cggagcatgt ctgtcgccct ccccgcttga tcccggacgg
    18181 gaggacgttc tcatcgatct gttcatccgg tcgaacgtac ccgcgatcga gatgcgaggc
    18241 ttcgatcagc cctccggagc ggcagcgcgc tataggaacg gctccgccgg ccaggtgctg
    18301 gcaagagtcg gctgccgtgc tgcagccgac cgcttcctcg agccggccgc gggagacggg
    18361 aagccttttg ctgccgccct gtgcgtcgac atggggttct ggcgatcggc cggaggagga
    18421 acgctcgatc tactgcgcga actcctggcg atgcgcgccg agggtcgcaa cagcggccgg
    18481 ccggcggggc gtgtcctgat cggcgtgctg ggagtctgcg gcagccgcga cggggcggcc
    18541 acggcattct cgatggggtg cgatttcatc cattccggct ccaccatggt cttcgccgag
    18601 gaagcccgtc tgcaagatgg cgcgaggctc gcgatctacg gtggcgcgga aggagtggtg
    18661 gaaacgctgc ctgactggtg gctccccgaa ctcgcctcga gatcgatgtt ctggctcgag
    18721 tgcggggcga catctcagga aatcagatcc ctccaggatt tatacctgcg cggatctgcc
    18781 gggatggcgg agatctacga cgtgatctcc cagctgggga tagagctccg acaccggatc
    18841 ggaaagccgg agacccacga ggcgagagga acgctcagag aagcggcagc cgttgtcttc
    18901 ggaagcagga ctgtgccttg cgatcccgct ttcctgcgct tccgggagtg gtccggcctc
    18961 cgcggatcgg acccgagcca gagcctgagt gcgtcgacca tagccgacct tctgatccct
    19021 gggatgccgg caggcgaaat ccaagccgcg aaaggagatc ggccgtggaa ctaacagacg
    19081 ctgatcggat cgaggaatac attgccggat tcatctcaaa ggaactcggc attcccgagt
    19141 ccgacgtgga ttatgacctg aacttcggag cgttcgggtt gagttcgatg tccggcatga
    19201 agctcgtcgg ccgactggag gaggaattac agacgaagat caagccaagc atgctgttcg
    19261 aaaatccaac gatctcaaaa cttgccgagg ccatcgccgc gaggggttct acctcgaacg
    19321 ccgcttagct gctggaacct gtcgagcggc gggaagaggt gctgcgcaaa tcgtaatcaa
    19381 tcgatcttct acgcagggag cacacgatgt ttgcaaaatc ggagatgacc gacttcgaac
    19441 tgttctccgc agcgggctcg ctgccggttc acgatgtcct cgcgatccgc acgtggctca
    19501 ctcccgacaa aacactcttc accttcctcg atgacgaagg tgaagagtgc aatcggctca
    19561 cgtacctcga tctttggcgc cgttgcagag cggtgggcgc aagcctcgcc gcagtgagcg
    19621 atccgggaga tcgcatcatg ctgttctacc cgcccggcct cgacttcatc tccgccttca
    19681 tcggctgcct gatggttggg cgtgtagcgg tcccctccaa ccttcccgcc cgtcggcgcg
    19741 tcgatcgctc ggtcaacatc gtcaccgatt gcggggcgaa ggtcgccatg ggcccctccg
    19801 atcaggttcc tgagttccgc aggagcttcg aaggaacgaa agccgagaca ctgcagtgga
    19861 tcgcgaccga tacgctgcct ctcgaggatg gcccgccgtg cctgcccgaa caaccctcct
    19921 cggtcgacat gggagcggtc gcctacctgc agtacacctc gggttcgaca tcgaatccca
    19981 agggcgtgat gatcacgttc ggcaacgtga cgaccaactg ccggatgatc cgcgacaccc
    20041 ttcggctgaa tcaagattct accatggtgt tctggcaacc ccaccatcac gacatgggct
    20101 tgatctgcgc ggtccttctg ccggtcgtca tcggaaacca caccgttctc atgacgccgg
    20161 caaccttcgt cagacaaccc atgctttgga tccagatcat ctcacgatac aaggcggagg
    20221 tcgccggagg cccgaatttc gcattcgaca tggccaccga gcgctacgcc cccgccaaga
    20281 tggaaggcgt cgacctgtcc aattggcgtc tcgcactgaa cggttctgac atcgtcagac
    20341 cgagcacgct ggatcgattc gctgagcggt tcggccctca tggctacagg cctgagacat
    20401 tcctgatatg ctatggcatg gcggaggcgg ttctgttcct gtcagccggc ccggtcggca
    20461 agaaaccccg ctacgctgca gtcgacatcg aagaactcga gcagcatcgg cgcgtgcagc
    20521 tcccgaccga tccgtccagg agtcggctgc tcgtgggatg tggcgagccg tcttgggaag
    20581 tggaggctat cgccgtcgaa ccggaaaccc gacgcaaact gccggtgggc gaggtcggcg
    20641 agatctggat ccacagtgcg actgtcggga tcggctattg ggagaacccg gaagagtcgg
    20701 atcgcacctt cagggcacac acggaggagg atgccggaaa gaactatctg cggaccggcg
    20761 acctgggctt catccatccg gaagaccgtc aggtttacat ctgcggaagg atcaaagacc
    20821 tcatcatatc cgaaggcagg aacgtacacc ccgaggatat cgaatacacc ataagcgagg
    20881 ctcttgctgc acgaggagaa tcaaagacga tttcgtccgt cgtcttcaac gtggagttca
    20941 atgatcgaca gctcatcgtg gccgccgttg aggtcgaccg ctctctcaaa cgggctctgc
    21001 ttgagaaggg agccgagatc gagagagcga tccgacaagc cgtcgcagcc gatcacggcg
    21061 tcacgttgca tcggctgttg ttcatcccgc cgtcaagcat gtgcaagacg accagcggaa
    21121 aggtgcagcg gggcctgatg cgtcagatct acgtgaacgg cgcactcagc gccttggaac
    21181 ccgtcggggc ggccgcgtga gcgtccagcc gggcatgctt ggcagatcct gggccgttct
    21241 cggggaggac gccccggagc agccgtgcct cgtgtgcttc catttcgccg gtggaagcgc
    21301 tcagagcttt cttccatggc gtaagcacgt ggtggggcgc tacaatcttc tcgcggccga
    21361 actgccggga cgagggcgac gttacggcga ggcattcgcc tcgtccgtcg acgaggcggc
    21421 cgcccaattt gccgaagagg cgcttcacct accccggaac ccgctcatct tcgtcgggca
    21481 cagcttgggc gcgttgctgg cctatgaaac ggcctacgcc atgcgcgaac gaggaggccg
    21541 gcaacctatc gggctggtcg cagcgggccg tcagtcaccg gacgtcgatc agcatggaag
    21601 gaatctgccc gacgcttcga tgtcggccat aagaaagtac ctgcaggaac tgtcaggtac
    21661 tccagaatcg atcctgcggg acgacgccta catgaccatg atgcgtccga tcctacaggc
    21721 tgatttcgat ctgctgagga gctaccggtt ccggccgcgg acgccgcttc agatacccgt
    21781 gcacgtcgtc ggcgccatcc acgatcacgc cgtcaaattc gagtctctgc tcggctggtc
    21841 gcgcctctcg gtcggcgagg tttcactgtc ccttatcgat ggcgggcatt tcgctccgat
    21901 cgagcaaccc gcctcaatac tcgacaaggc cgatcgcatc gccggcggcg tcgcgtctac
    21961 ctcgatcgga gagcagttcg cgccggcttg cgcctgaagc caccttccct gccgcacctc
    22021 agatccatga gcagggacgg tacgtacggg gacgtagaag aaatctccgg aaggatcagg
    22081 aacacccgca aacgaaggga acaacgcatg acagcatctc aatcgctgac tcacgaagcg
    22141 gacccagcca gcatcgtagc tggtctaaaa gcgagcttcg agacggcagc ttctgccata
    22201 aacggaagca cagtcctaaa gttggcggca gacaaagagg actgggtgga tacgggtgtc
    22261 ttcgttaaag aaggtcagga ggtcagcctc ctgtcggaag gtgttatctg gctatctcgc
    22321 gaatttgaca ttcaggtaaa aggaaacgcg gcgctctggt atagagttgg aaacggcacg
    22381 atcgaaaaat cggctggcag aaccactacg ttccgcgccg accgggatgg ccctctgcaa
    22441 ctcgcctgcc gcttggcagg tcattggctc gatgacaccg gcagactgga tccggatgtc
    22501 ccgcccatgc cgatggaggg ggcgctcacc gttggggttg cagcctggga gactgacgcc
    22561 aaggaagggc tcgaaagact cgccggcagc gacgataccg atctggcaca agctgaactg
    22621 gagcggctcc ggtcgtcaag gccgctccca aaggggtggg atcacctttg gcgcgtcggg
    22681 cgaaccgaca tcttctgcga gtcggtcacc gagggtggcc ctgtcctgtc ctgcaactgc
    22741 acagcggact cgggcatcat caagtacccg gtcgacgtgg ctctcgatcg ttcgacaacc
    22801 ctgtcttggg agtggctggt tcgggcgctc ccatcggagg tgccggaaaa cacgctagtc
    22861 acccatgact acttgtccat agccgtcgaa ttcgagaacg ggcaggactt gacctacttc
    22921 tggagctcga cgcttccact ggaaacgtcg ttccgctgtc ctataccagg ctgggagaag
    22981 cgtgagaccc acatcgtagt acggacgggc caggagcagg tcggaacttg ggtggccgac
    23041 agtcgaggtg tccttgccga ctacgaggcc gctgttggtg tcgagcaccc cggaagagtc
    23101 gtcggggtat ggatcatcgc actcagcccc ttccagcgca ggaacggccg ggccgagtac
    23161 cggaaaatca aactgtcctc ggacacggag acggtcgagg tcgggcccta gcccggacta
    23221 gcgcttcacg aacggtgcac cgagctaccg gtccgaaacc ggcatcccct ccgcgccccc
    23281 gggacgcggc aggctgatcg aaccggagta cggctttcca gcagatactg cacccacgag
    23341 tgccttccta cctagcgtca ctcgccggcc gaataggaga gagcaatgtt cattaaggtc
    23401 tcgcaggttt ctggcctgga gctgaacaag cccacgcata tcgaggttga aggtatcgat
    23461 ctcgttctgc tcggcaccgg aagcaagatc tcgctgttcg agagcagatg cccccatcag
    23521 ggcgcatttc tccatgaagg tgccgtccgg aatggtgcgc ttgtatgccg agctcacggc
    23581 tgggcgttcg acgccgatac gggtgtgtgc cgcgggaagc agggcatcgc cctgacctcc
    23641 attccactga ggatcgaagg cgacgacatc ctagccgacg ccgaggctgt acgcgccctg
    23701 gccgatagaa ggaaaacgga gggtcgctcg agcgaaactg tggcgagcgt tatccaatcg
    23761 cagaggacta taaacgatct tcccggcccg gcgggattgc cggtcttggg taacgcacac
    23821 cagatcaatc tggagcaact gcatgtcacg atggaaaact ggcacgagca gtacggctcg
    23881 ttcttcaagt tccgtatcct ccggcagaac gccattgcag tagcgcaccc tcacctcatc
    23941 cgcatggtct tacgcgagcg gccgcacaac ttccgcagga tcagctccat cgaatccgtt
    24001 tttcaggaaa tgcatgcaca gggcctcttc tccgtggaaa aagaggagtg gcggtatcaa
    24061 cgtcggatcg ttgctcaggc tttgaacgcc cggcaaatcc gcctattctt cccgaagatg
    24121 caacagatta ccgagagact gatgcggcgt tggtcgagag ccagcgaaga cggccgtgtt
    24181 gtggacgttc aagaagacct gatgcggtat acagtggacg tcacgtcaaa cctatccttc
    24241 aattatgaca tgaacacagt cgaaaaagaa ggtgacgtca tacaggacca cctagaacac
    24301 gtattcccaa tgataagccg tcgcgtaaac tcagccgttc cctactggcg gtatttcaag
    24361 tttcagagag acagggacct cgacaaagcg cttgtcgcat taaaagggat catcgacgat
    24421 atcattgaca agagcaggga caggctcaag caaaacggcg gaaacgtcga agcgggcaac
    24481 ctcgtagagg ctatgctgca actccaagag accgaggggg ccattacgaa cgacgcgata
    24541 tttggaaacg tattttcact ccttatagcc ggcgaagaca caactgcgaa cacaatggtc
    24601 tggatccttc atttcctcag ctccaggccg gaagtcttca agcgaatgca ggaggaggct
    24661 gacgaggttc tcggtggatc cgatgtgctg cccgacctgg agacagccaa ccgtctcatc
    24721 taccatgacg cggtgatcaa cgaggctttg cgcctcaagc cggtagcgtc gatttggccg
    24781 atggaggcat gctccgatgt cgtcatggac ggcgttgctg tcccagcagg cacgccggtg
    24841 ttcttgctta ctcggattcc cactttggtc gacgagaatg gcgtccctgc cccggagttc
    24901 gatccggaaa ggtggctcag gaaggacgcg tcgacgacgc atttcgacaa cgtgatggta
    24961 cctttcggtg ccggtccgag attgtgccct ggccgcagcc tcagccttct ggagatccga
    25021 gcagtgatgt cgatggtatc tcgacgcttc gaactcgaac taccaaccga tggtccttca
    25081 gtcggcgaga ggttcgcgtt tacgctgatc ccgacaaacg ttcgtctgag attcaaggaa
    25141 agaaataagt accctgctgg gccgcagttt attgcgccaa cggcagagtc cgtgcgtttg
    25201 ggagcgtga
//
