BGC0001991: toblerol A biosynthetic gene cluster from Methylorubrum extorquens AM1
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Location: 7,676 - 32,884 nt. (total: 25,209 nt).
This entry is originally from NCBI GenBank NC_012811.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0001991
Short description toblerol A biosynthetic gene cluster from Methylorubrum extorquens AM1
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: NC_012811.1
Compounds
  • toblerol A
  • toblerol B
  • toblerol C
  • toblerol D
  • toblerol E
  • toblerol F
  • toblerol G
  • toblerol H
Species Methylorubrum extorquens AM1 [taxonomy]
References
Chemical products information
toblerol A
(no structure information available)
toblerol B
(no structure information available)
toblerol C
(no structure information available)
toblerol D
(no structure information available)
toblerol E
(no structure information available)
toblerol F
(no structure information available)
toblerol G
(no structure information available)
toblerol H
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • MEXAM1_RS33125
  • WP_003598534.1
7676 - 8416 (+) SDR family oxidoreductase
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  • MEXAM1_RS25395
  • WP_003598535.1
8472 - 15308 (+) SDR family NAD(P)-dependent oxidoreductase
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  • MEXAM1_RS25400
  • WP_003598536.1
15360 - 16652 (+) NAD(P)-binding domain-containing protein
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  • MEXAM1_RS25405
  • WP_003598537.1
16702 - 21726 (+) aminotransferase class III-fold pyridoxal phosphate-dependent enzyme
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  • MEXAM1_RS25410
  • WP_012753526.1
21756 - 24737 (+) polyketide synthase
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  • MEXAM1_RS25415
  • WP_003598540.1
24734 - 26749 (+) acyltransferase domain-containing protein
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  • MEXAM1_RS25420
  • WP_003598542.1
26740 - 27003 (+) acyl carrier protein
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  • MEXAM1_RS25425
  • WP_244426980.1
27100 - 28875 (+) fatty acyl-AMP ligase
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  • MEXAM1_RS25430
  • WP_244426981.1
29004 - 29672 (+) alpha/beta fold hydrolase
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  • MEXAM1_RS35190
  • WP_244426982.1
29783 - 30886 (+) DUF3047 domain-containing protein
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  • MEXAM1_RS25440
  • WP_003598550.1
31061 - 32884 (+) cytochrome P450
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
Detailed domain annotation
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Modifications to original record
  • MEXAM1_RS34780 crossed the origin and was split into two features