BGC0001991: toblerol A biosynthetic gene cluster from Methylorubrum extorquens AM1
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Location: 7,676 - 32,884 nt. (total: 25,209 nt).
This entry is originally from NCBI GenBank NC_012811.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0001991
Short description toblerol A biosynthetic gene cluster from Methylorubrum extorquens AM1
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
NC_012811.1
7676 - 32884
via
Compounds
  • toblerol A
  • toblerol B
  • toblerol C
  • toblerol D
  • toblerol E
  • toblerol F
  • toblerol G
  • toblerol H
Species Methylorubrum extorquens AM1 [taxonomy]
References
Chemical products information
toblerol A Evidence:
(no structure information available)
toblerol B Evidence:
(no structure information available)
toblerol C Evidence:
(no structure information available)
toblerol D Evidence:
(no structure information available)
toblerol E Evidence:
(no structure information available)
toblerol F Evidence:
(no structure information available)
toblerol G Evidence:
(no structure information available)
toblerol H Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • MEXAM1_RS33125
  • WP_003598534.1
 7676 - 8416 (+) SDR family oxidoreductase
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    • MEXAM1_RS25395
    • WP_003598535.1
    		 8472 - 15308 (+) SDR family NAD(P)-dependent oxidoreductase
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      • MEXAM1_RS25400
      • WP_003598536.1
      		 15360 - 16652 (+) NAD(P)-binding domain-containing protein
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        • MEXAM1_RS25405
        • WP_003598537.1
        		 16702 - 21726 (+) aminotransferase class III-fold pyridoxal phosphate-dependent enzyme
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          • MEXAM1_RS25410
          • WP_012753526.1
          		 21756 - 24737 (+) polyketide synthase
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            • MEXAM1_RS25415
            • WP_003598540.1
            		 24734 - 26749 (+) acyltransferase domain-containing protein
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              • MEXAM1_RS25420
              • WP_003598542.1
              		 26740 - 27003 (+) acyl carrier protein
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                • MEXAM1_RS25425
                • WP_244426980.1
                		 27100 - 28875 (+) fatty acyl-AMP ligase
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                  • MEXAM1_RS25430
                  • WP_275450678.1
                  		 28890 - 29672 (+) alpha/beta fold hydrolase
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                    • MEXAM1_RS35190
                    • WP_244426982.1
                    		 29783 - 30886 (+) DUF3047 domain-containing protein
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                      • MEXAM1_RS25440
                      • WP_003598550.1
                      		 31061 - 32884 (+) cytochrome P450
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                        Biosynthesis information
                        Annotation changelog

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        Detailed domain annotation
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                        Modifications to original record
                        • MEXAM1_RS34780 crossed the origin and was split into two features