LOCUS       BGC0001995             27487 bp    DNA     linear   CON 04-APR-2018
DEFINITION  Aspergillus oryzae RIB40 DNA, chromosome 7.
ACCESSION   BGC0001995
VERSION     BGC0001995
KEYWORDS    .
SOURCE      Aspergillus oryzae RIB40
  ORGANISM  Aspergillus oryzae RIB40
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to BA000055.
            This genome assembly has been updated so
            as to reflect the location and orientation of
            contigs on the chromosomes. Gap lengths were
            estimated using the results from Optical
            Mapping (http://www.bio.nite.go.jp/dogan/project/view/AO). This
            Aspergillus oryzae RIB40 genome consists of a nuclear genome
            assembly represented by eight chromosomes (assembled from 24
            entries) and three unplaced contigs (AP007156, AP007160 and
            AP007177) and a complete mitochondrial genome (AP007176).
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 16:40:47
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1039553
            Orig. end    :: 1067040
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..>1018
                     /db_xref="GeneID:5998148"
                     /locus_tag="AO090011000406"
     mRNA            join(<1..199,285..404,456..>1018)
                     /db_xref="GeneID:5998148"
                     /locus_tag="AO090011000406"
                     /product="unnamed protein product"
                     /transcript_id="XM_023232935.1"
     CDS             join(1..199,285..404,456..1018)
                     /codon_start=1
                     /db_xref="GeneID:5998148"
                     /locus_tag="AO090011000406"
                     /note="unnamed protein product; predicted protein"
                     /protein_id="XP_023093491.1"
                     /transl_table=11
                     /translation="MPNSWHGQHLACHPVIDGVRNLYGYQPSLAAGVFFSILFTILMIF
                     HVVHCIRRKTWWCMVFAIGCLVEVLGWAARTWSAKCPYTKSAFLMQLATLVIGQDNCDM
                     LRTGIYLLLGYIIRIFGRKSSYFRSDCYFWFFTVCDLISLVVQAVGGALASAALSAHRD
                     MSNGTHIMIAGIAFQMASTLAFATCMVDCVLRTIHRPRGTIPKSVSFLFAAMVLSVLCI
                     CTRSIYRLAELSQGWTGYLITHEKYFIILDAVMMAIAVGIFVIFHPSLMVSAAANPPMG
                     RRYRELAPINVK"
     subregion       1..27487
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="terpene"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..27487
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(<4993..>5542)
                     /db_xref="GeneID:5998149"
                     /locus_tag="AO090011000408"
     mRNA            complement(join(<4993..5189,5257..>5542))
                     /db_xref="GeneID:5998149"
                     /locus_tag="AO090011000408"
                     /product="unnamed protein product"
                     /transcript_id="XM_001825994.3"
     CDS             complement(join(4993..5189,5257..5542))
                     /codon_start=1
                     /db_xref="GeneID:5998149"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Terpene synthase/cyclase metal-binding domain
                     protein (Score: 55.9; E-value: 7.4e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="AO090011000408"
                     /note="unnamed protein product; predicted protein"
                     /protein_id="XP_001826046.3"
                     /sec_met_domain="Terpene_synth_C (E-value: 1.4e-08,
                     bitscore: 24.0, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWWPRATADRLQTCTFWFLWLFTWDDEIDQSTSDLFIHIHKANDF
                     RKESLEYVKFCLGVGDDETAKWDFQNNPPNRPLIRSLDVIGAHLQKVYNHDQIMTFVNE
                     IDYYMGCQQREQKRKLTGRLPIVAEYLETRMGTSAVTSMLALNEYGGALILGLKRR"
     gene            <7507..>9051
                     /db_xref="GeneID:5998150"
                     /locus_tag="AO090011000410"
     mRNA            join(<7507..7748,7802..7839,7885..8148,8211..8869,
                     8923..>9051)
                     /db_xref="GeneID:5998150"
                     /locus_tag="AO090011000410"
                     /product="unnamed protein product"
                     /transcript_id="XM_023232936.1"
     CDS             join(7507..7748,7802..7839,7885..8148,8211..8869,
                     8923..9051)
                     /codon_start=1
                     /db_xref="GeneID:5998150"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 212.5; E-value: 1.8e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090011000410"
                     /note="unnamed protein product; predicted protein"
                     /protein_id="XP_023093492.1"
                     /sec_met_domain="p450 (E-value: 4e-44, bitscore: 140.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQNMIIPSFWTGTAIIGLVACAYVSYQCLLSPLARFPGPFAAKL
                     SKGWRAYKTANGQWHRKLVDLHRKYGHVVRIAPNELSVGDPSSFRKIYSPAEAGNGFNK
                     AACYSVVQGNRPFDLTGERNEKVHSEQRKLVATAYSMSSMVHFESKVNVVIETVIHKLE
                     ARCRKTIDLGHWLQMWAFEPTRPLLNSLKPDVIGSVSFSQPFGYVESGDDEGVFKRIQN
                     AMGSAAWLMHAGWLFRLHQKLIPICGNWLAVNDRNGYFFQVACREVSGRINRGGDDKDI
                     IGQLLETQKIKPQLKDLDISFMMTSNVFAGSDSTSIAFQSIFYLLLTHPAAHDRLMREL
                     REREEKGELSDPVSFQEAESWPYLQAIIYEAMRLYAPAAFVLDRVVPPEGMMIEDKFVP
                     GNTVVGSSAWVIHRNPEIWGPDVDTFRPERWLDDRKDEYSTFLI"
     gene            complement(<9822..>11638)
                     /db_xref="GeneID:5998151"
                     /locus_tag="AO090011000411"
     mRNA            complement(join(<9822..10378,10431..10518,10593..10846,
                     10909..10939,11000..11491,11558..>11638))
                     /db_xref="GeneID:5998151"
                     /locus_tag="AO090011000411"
                     /product="unnamed protein product"
                     /transcript_id="XM_023232937.1"
     CDS             complement(join(9822..10378,10431..10518,10593..10846,
                     10909..10939,11000..11491,11558..11638))
                     /codon_start=1
                     /db_xref="GeneID:5998151"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 307.6; E-value: 2.6e-93)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090011000411"
                     /note="unnamed protein product; cytochrome P450
                     CYP4/CYP19/CYP26 subfamilies"
                     /protein_id="XP_023093493.1"
                     /sec_met_domain="p450 (E-value: 9.2e-60, bitscore: 192.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSISALFSAGGFQWILLSLSLAFIVVYSLFYLAVGLYNLYFHPL
                     ARYPGPLLGRASSLWYARSLARGTVAQDTLKLHEKYGDVVRIAPDELSFIQPENWSAIY
                     GHQLGKDYRELIKDPRYHDTVKPTPTILTGDWDEHTFYRKILSNSFSEKSLKDQEHILH
                     HFVDLFVQRLKETSAEGTRELNMTDQWNYLTFDVIGFLTYGEEFHCLTSSKLHDWIEAM
                     LCVAILMSLGQAARHLPFPFDKIYKQWAIPSNVKRQVALHRDLTEVAIPHIPIQYASAY
                     RLNSRKGDIPYSVLKEHANILTIGGSETTATLLAGATFHLGKNPPVLQKLATEIRTTFV
                     NDGEITVARLSECKYLLATVEECLRIYPPSPANHTRMVPKEGIVLNDQHIPGGIGVGMP
                     MYAAFRASSNFTYPDRFAPERWLGDPMYSKDKKGALQPFSFGPRNCLGRHLAYQEIKLA
                     LAKLVYHFDLELNPKCGDWDEQKNFTFWVKPPLWVNLHPVKS"
     gene            <12347..>14222
                     /db_xref="GeneID:5998152"
                     /locus_tag="AO090011000412"
     mRNA            join(<12347..12778,12842..12944,13004..13072,13126..13734,
                     13789..>14222)
                     /db_xref="GeneID:5998152"
                     /locus_tag="AO090011000412"
                     /product="unnamed protein product"
                     /transcript_id="XM_001825997.1"
     CDS             join(12347..12778,12842..12944,13004..13072,13126..13734,
                     13789..14222)
                     /codon_start=1
                     /db_xref="GeneID:5998152"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 132.2; E-value: 4.3e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090011000412"
                     /note="unnamed protein product; predicted protein"
                     /protein_id="XP_001826049.1"
                     /sec_met_domain="p450 (E-value: 2.3e-45, bitscore: 144.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHFNLAGPESNTSITSLEWLGIKNSFTGSHWAHITGLSELHPTG
                     FLCLIATLIIGIVHLTRGPKPTVLPVVNPPGTFELTANRVKKEWLVDARQIIRRGFEKF
                     PGKPFNMIAADVGLTTVLPPEYASEIRNNPSLSFVAFMAHLFFSELPGFEPTREGMFDN
                     DIGITVVHKYLTVNLARITEPLSREATAALKDIFTDNSEWHDANLKAINLALVARLSSR
                     IFLGEELCRNEEWLKITVNYTVDVMKAAERLRRVPGPLRRIVHWFLPEAQKCRDEVKRA
                     GKVIRPVLEKRRREKATMESEGKEALQYNDAIEWFEQMAKSQGTSYDPEVVQLFLSTVA
                     IHTTSDLLTVVMADLARNPEIIEPLREEISSVLRDGGWKKTSLTDMKLLDSVLKESLRL
                     KPIAVVSMRRVAMDHLKLSDGTFLPKGTKMAVSSHRMWDPDVYENPEQWDGFRYVNLRE
                     TPGQDKHAQFVSTSERHLGFGHGKHACPGRFFASSELKVALCHILMKYDFELAPGTVVQ
                     HRYSGASYYADPAIRVMLRRRNVALPSWFER"
     gene            complement(<14333..>15906)
                     /db_xref="GeneID:5998153"
                     /locus_tag="AO090011000413"
     mRNA            complement(join(<14333..15142,15214..15685,15737..>15906))
                     /db_xref="GeneID:5998153"
                     /locus_tag="AO090011000413"
                     /product="unnamed protein product"
                     /transcript_id="XM_023232938.1"
     CDS             complement(join(14333..15142,15214..15685,15737..15906))
                     /codon_start=1
                     /db_xref="GeneID:5998153"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 95.1; E-value:
                     5.3e-29)"
                     /gene_kind="transport"
                     /locus_tag="AO090011000413"
                     /note="unnamed protein product; synaptic vesicle
                     transporter SVOP and related transporters (major
                     facilitator superfamily)"
                     /protein_id="XP_023093494.1"
                     /transl_table=11
                     /translation="METPAGKADRPRDHDSEQSQDNVVSWEGEDDPTNPLNWSPLAKWV
                     HVAIISIGTFTIAREKSPLASSIFAPGVVELAHEFHEENQLLTTIVVSIFVLGLAFGPL
                     LAAPISEMYGRWICYTVFNILYTIFTVACGVSTNISMLIVFRFFAGVTGSAPLTIGGGT
                     VADLFPMHQRGLALSFVTLGQAVAPAIGPVAGGFLTQNLGWRWVFWLLTIVNGTITICQ
                     ILFTRETYAMTILNRRAKRLRKTTVHSSVTHRSVNFAIFFYSLVRPCKLLLLSPISLIV
                     ALCCAVIYGILYVLVTTFSPVFQDTYHFSIGISGLGYLGLGIGNLVGLWIFSMTSDRYM
                     VAQANRFGSAKPEHRLPMMILSGPVIAAGLFWYGWSVQARIHWMMPIVGSGIVGLGNMF
                     FFMPMVSYLVDSFPTYAASAIAANAVLRSIGGAVLPLAGQRMYDTLGFGWGNSILAFMA
                     LVFNPLLIAIYRYGEYIRTRWQVKL"
     gene            complement(<16377..>17497)
                     /db_xref="GeneID:5998154"
                     /locus_tag="AO090011000414"
     mRNA            complement(join(<16377..16573,16622..17303,17372..>17497))
                     /db_xref="GeneID:5998154"
                     /locus_tag="AO090011000414"
                     /product="unnamed protein product"
                     /transcript_id="XM_001825999.3"
     CDS             complement(join(16377..16573,16622..17303,17372..17497))
                     /codon_start=1
                     /db_xref="GeneID:5998154"
                     /locus_tag="AO090011000414"
                     /note="unnamed protein product; glyceraldehyde 3-phosphate
                     dehydrogenase"
                     /protein_id="XP_001826051.1"
                     /transl_table=11
                     /translation="MTAKVGINGFGRIGRIVFRNSFSHENTEVVMVNDPFIEVQYAAYM
                     LKYDSTHGNFEYDVHIDGDSIVVNGKKVKFYAEKDPAKIPWKDAGAEYIIESTGVFTTV
                     EKASAHLQGGAKKVIISAPSADAPMYVMGVNEKTYAGADVVSNASCTTNCLAPLTKVLH
                     ERFGVVEGLMTAVHAYTATQKLVDAPSKKDWRGGRAAAQNLIPSSTGAAKAVGKVIPEL
                     QGKVTGMSIRVPTSNVSVVDLTCRLEKGASYEEIITAIKEAAQGELKGILDYTEDDVVS
                     SDMKGNPHSSIVDIKAGISLNPNFLKIVSWYDNEWGYSRRVLDLTAYIASVGK"
     gene            <18241..>20154
                     /db_xref="GeneID:5998155"
                     /locus_tag="AO090011000415"
     mRNA            join(<18241..18457,18517..18651,18713..19131,19183..19521,
                     19577..19684,19751..19908,19965..>20154)
                     /db_xref="GeneID:5998155"
                     /locus_tag="AO090011000415"
                     /product="unnamed protein product"
                     /transcript_id="XM_001826000.1"
     CDS             join(18241..18457,18517..18651,18713..19131,19183..19521,
                     19577..19684,19751..19908,19965..20154)
                     /codon_start=1
                     /db_xref="GeneID:5998155"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 270.3; E-value: 5.3e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AO090011000415"
                     /note="unnamed protein product; cytochrome P450"
                     /protein_id="XP_001826052.1"
                     /sec_met_domain="p450 (E-value: 5e-59, bitscore: 189.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASLTGAAAVLLAFILAYSTALTIYRLFFHPLARFPGPRLAAATK
                     WYEFYFDIIKSPGGQFFKELSRMHDVYGPIVRVNPDEIHVRDAAWFEVLYAPNPTKRNK
                     YRPSAEMAGLTLGIHGTVDHDLHRRRRMAIAPMFNKQSILSAEHLIKQHIDELTDVFES
                     YLGTNNPINLQTTFLAYTTDVLYHYMFDTDAGYQRDSGAAQQWRHSMDAVAQATPFLKQ
                     FPSLLSRVALIPLPMLIWVLKRIQPDVAGLLGTHQLMASIVSKYMASKPEEDQDELIAT
                     KAVKPRTLFHAIEASSLPPHEKAPTRLAQEGLTVLFAGGETGSRLLAHTVYHLLKNPEI
                     LEKVRKEILDAAGDSNQLPDMKALEALPWLTASVRESLRLRAATTSRLPLVTEKPLAYA
                     DWVIPPNTPVSMSHGDILHNEDIFPDPMKFMPSRWFNASPQQNRLFVPFGKGTRMCVGM
                     NFAYCEIYMSLAVILARFDLELYDTRWERDVHYTRDCFLGEPDPASPGIRVKVVADHKT
                     FTRS"
     gene            complement(<20404..>21111)
                     /db_xref="GeneID:5998156"
                     /locus_tag="AO090011000416"
     mRNA            complement(<20404..>21111)
                     /db_xref="GeneID:5998156"
                     /locus_tag="AO090011000416"
                     /product="unnamed protein product"
                     /transcript_id="XM_001826001.3"
     CDS             complement(20404..21111)
                     /codon_start=1
                     /db_xref="GeneID:5998156"
                     /locus_tag="AO090011000416"
                     /note="unnamed protein product; predicted protein"
                     /protein_id="XP_001826053.1"
                     /transl_table=11
                     /translation="MAETWMALPLFNRQNSPESSRDVLSMASPGLLPIDPSPEHDETNK
                     FGPFDLLDNLPGELQLPADLNPARVGPTTHLPDLTDRADPEPRWMQISDLEVVGPGAVT
                     CPFPGCKSTLRFTGSRELRRHYKQHFKRFFCRYPHCPQAGPGLQGPHPSTKRGFATRKD
                     RARHEAKHDPRIQCPCLDERGERCSRMFSRLDNMRDHVRRIHNNSHYAGQETHGTADAI
                     PDIDIHHEIEARS"
     gene            <22645..>23995
                     /db_xref="GeneID:5998157"
                     /locus_tag="AO090011000417"
     mRNA            join(<22645..23031,23093..>23995)
                     /db_xref="GeneID:5998157"
                     /locus_tag="AO090011000417"
                     /product="unnamed protein product"
                     /transcript_id="XM_023232941.1"
     CDS             join(22645..23031,23093..23995)
                     /codon_start=1
                     /db_xref="GeneID:5998157"
                     /locus_tag="AO090011000417"
                     /note="unnamed protein product; predicted protein"
                     /protein_id="XP_023093495.1"
                     /transl_table=11
                     /translation="MISMSVPRKKQEREISLLMHYVDDVFPHQFPIYHSQFVGKREWLL
                     PLLSSTRSVYYATLCLSLLHKEKSSNLDQPGSVSFCQEERLRYYILALRETQQLLQQLS
                     PVCDLEAMRSCVPSLASALHLISYESSCPVYGDWKVHLQAATSLIPILVGGWNSMIKPI
                     KHTSTLWTGLTLSDFHDLHTEGSLSYEDASALRFLTNALAVTGILSFISTGPTSALSDY
                     RYLMDATCDMVQCDQFLGCENWVMSAILDVGLLDRWKREEEGNRRLSFRELANRAKRLE
                     DCLENGIRELSAKTSGSSDAVSSITRIYASSTLTYLHSVVSGLNPDLSEIQESVSRTIE
                     LLKELSNWHLLACLTWPLCVTGCMAAPDHEAFFHSLAISAEISPHSLRHTWIVLRILKD
                     VGKVRGSLGEQILPTWEQILCIDGAPILLT"
     gene            <24670..>27487
                     /db_xref="GeneID:5998158"
                     /locus_tag="AO090011000418"
     mRNA            join(<24670..24790,25820..26148,26216..>27487)
                     /db_xref="GeneID:5998158"
                     /locus_tag="AO090011000418"
                     /product="unnamed protein product"
                     /transcript_id="XM_023232942.1"
     CDS             join(24670..24790,25820..26148,26216..27487)
                     /codon_start=1
                     /db_xref="GeneID:5998158"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 108; E-value:
                     6.3e-33)"
                     /gene_kind="transport"
                     /locus_tag="AO090011000418"
                     /note="unnamed protein product; synaptic vesicle
                     transporter SVOP and related transporters (major
                     facilitator superfamily)"
                     /protein_id="XP_023093496.1"
                     /transl_table=11
                     /translation="MPHGAVCLDVATDTIRADDIGIALDFLRWLIFGCKDDMRNLVSMA
                     HGNQSTNETEDISPVNSIIRSKDQTDETKVDNNELYPVGNECDKNDDAPYCSLSERRKI
                     SVMLIASFSGIISPISASIYYPALPTIAKDMHVSISLINLTIMTYLILQGISPSFTGSF
                     SDVYGRRLAYMLCFITYIGANIGLALQSDYAALMVLRCVQAAGSSGTIAIGSAVVADIS
                     TRAERGKYIAYATMGTTLGPALGPVLGGLLDHFLGWRWVFWFLVILGGFNFTLILVACP
                     ETCRAVVGNGSIPPAKWNRPLWVILRDSLRPQSHKAGKRVDYETLERSKTRPNPLTSVR
                     IALEKEGGLILIYGALLYAGYMIILSTLTSQLESEYGFNSIQVGLCYLPMGIGSLTSRW
                     SAGPLLDWNFKREAKRQNLPIVKNRQQDIRDFNIERTRLTITIPFVYAGCLFLLAYGWV
                     MRFQTHLAVPLVLLFFSGHLTTGAFSTLSTLIVDIHRQSAATAVAANNLFRCLLAAGAT
                     AFAAPLIDRIGIGWTTTFIVGVWIVFSACLWAVYLWGHKWRDELRVKRSEGDGSPA"
ORIGIN
        1 atgccaaact cctggcatgg ccagcacctg gcctgtcatc cagtcatcga cggtgtgcgg
       61 aatctatatg gatatcagcc ttctttggca gctggagtgt tcttctcgat cctcttcacc
      121 atattgatga tttttcatgt tgttcattgt attcgcagaa aaacatggtg gtgtatggtc
      181 ttcgccattg gctgcttagg tgcgtcaaca catccttacc ctatctctta taactcattt
      241 caatatagag ggtagtgtgg gctaatattc atattgccat atagttgagg tcctggggtg
      301 ggctgctaga acatggtcgg ctaaatgccc atataccaag tctgcatttc ttatgcagct
      361 cgctacactg gtcataggtc aggataattg tgatatgcta cggagttcag ccagcagctt
      421 agctaactaa tatccagccc caaccttttt ctcagccgga atttacttac tcttggggta
      481 tatcatccga atcttcggac ggaaatcttc ctacttccgg tcagattgct acttctggtt
      541 cttcaccgtc tgcgatctca tttccctcgt agtccaagcg gttggggggg ctcttgcttc
      601 cgctgcactc agtgctcacc gtgatatgag caatgggacc catatcatga ttgccggtat
      661 tgcatttcag atggcctcaa cactcgcctt tgccacctgc atggtggatt gtgtcttgag
      721 aaccatccat cgcccgcgag gtacgattcc caaaagcgtc tcatttctgt ttgctgctat
      781 ggttctcagt gttctatgta tctgtactcg aagtatatac cggctcgctg agctgtctca
      841 aggatggacg ggttatctca tcacacatga gaaatatttc atcatattgg atgcagtaat
      901 gatggctata gcagtcggaa tctttgttat cttccatcct agtttgatgg tatctgcagc
      961 agctaatcca ccgatgggaa gacgctatcg ggagctggcg ccgatcaatg tcaaataaac
     1021 aaagtgcata tgatatatcc aaagatacat actttgggat gagatgtgta gttaattttg
     1081 gggtggggtg tcgatcaaaa ctgaatcata cctgctgcat acctcgctgg atgtgcatct
     1141 gggaagcaag gggctgcctt gtactgtgga tatccacaaa caggaaaaaa aatgaaccac
     1201 caaaaaaaaa actctcaata gagtctattg catagtggct gcagcttttg ctctcggaca
     1261 tgagtagata gtgttagaag gcgtgtgagg atcttaactg cgcgccgctt tgcagaatga
     1321 tagtgggtta tatgtaatat gtcgcgttca aattggttgt tttcaccagc tgcagcaatc
     1381 tgagaattcc agacattctc aatatcgcct ggaatcctat ctcaatcata ttagacagtg
     1441 gtctgaaccc gtgcaaggca tccctctctc atctgttaat gaaaatagcg tggataaatg
     1501 cgaaaagccg ccccaacctg ccatcaaaaa tctactgaga cgagctgaaa tgtctagtga
     1561 agtggcactt cgatcagggg acagcccatt ctgcctcgac gataaagctg agaccgctag
     1621 actaagccga ttacagctgt taggtatttc tggcatatac atcggtaaat tttccccatt
     1681 gtcccctaaa gactctccaa gtgacaaaaa gcataggtgt tctcctggca agctccgggg
     1741 acacgttggt tgttgccgtt tacaactcta tcggctcgga tttccacgat ctctcaaaag
     1801 gggcatggct gcttgtgtcg tatagtttag gttcttgtat ttcctcccct acagtaagta
     1861 gcttccgaac gactcgttct ttgctttcgt gcagtgttga tgcaaacccc gtgggccagt
     1921 tcggggcact tgatgaactt tttggaagga agacgacgct gttatggaca tattttctct
     1981 tcgctgctgg aaatatatta tggtttgtcc agtcgttgat accaatttca tgctaaggat
     2041 attccctagc taatttcttt ttatttgctt ttattatatg ttgcagcgga gctagcactt
     2101 caatgcctca gctagtagca gcaagagtat tagttggact tactagtgcg ggaatagttt
     2161 cctcatcatc cgccactgtg accggtgaga attacacgaa attggaagtc cctactatac
     2221 taatattgga aagcgctcat cccgtccgat aaggctactt ggcttcgaag ttacgccgat
     2281 gtggccaata ccattgggcg cagcgtagga gctgcagtcg gattcctgtt cacaaaaaca
     2341 atcggatgga gatggtgaag tacctcgaag tatcttccaa ggctattgtt cgttctaact
     2401 gttgccaaat aatataggtg cttctatagt aacgtgccgc tgattcttct ctgcgctttt
     2461 attgtcgtac aacagattcc acctgattcg ccaaagtctt cgcaaagcat ggacgacagt
     2521 cttccttccg aagtccagag cattgattgg gctggtgtat tcactctcac aatcacatta
     2581 gtgcaactaa ttctcttcat ccagactctt caaccaggcc agatccagca agcccgtatg
     2641 ttatacataa caggggctgg gtctattttc tccatatcaa tctttgtttg gatagagaca
     2701 tgctgggcgc actatcccct actccctctt aactccatga aaaaggcatt tggaggatac
     2761 tgtctttcac aattcttaat actgtccggc cggaccgggg tgagtaaatg tctttcctag
     2821 taacgtattt atttattgct gattataaca tctacgagta gctcctcacc agtgtagttc
     2881 cttacttcac tcgagctaac attggaggtg atatcacaac tctcctagca ggtggcatgt
     2941 tacttgttgg cctacctttc ggagggattc tagcaaatca cgtagtgaga cggtgagtct
     3001 cctcacaacg catcatcgtt attcgacccc gcttatagct ctcatctcgg ttaaggacac
     3061 gccattataa acgcctaggg ctcatcacaa tcattctact cgtgttaacc tatcttgtcg
     3121 tcttcctacg gtggcgggag ggtatacaca tttgggagat agtgtttctg ttcccttcag
     3181 gtttagcagc ggggatgttt cttgctactc agttcattgg catgactgcg gagctaacag
     3241 gaaataactt aatacaatgc acaggcacgt actacttatt ccaacagctg ggtagaattc
     3301 taggccctgc cataggtttc gctttgatcc agggaaattt ccaggcgaga ttaaactgga
     3361 agctacgggg tctgcctaat acctcagagg taggtttact tcaatcttaa gctatgtcag
     3421 aagtctaaag agttcctagc tggtccggaa tatcctcaac gatgacaaat tctctcgtac
     3481 attgccagct ccaatgcagg atgttgtccg tgaatgctac ttgtatgggt ttcaatttgc
     3541 tgcacgtaag tgtcatcatt gcatcttagt gatcagggat cttaacattg tagcgcagtg
     3601 ttttcgatat tcagtactat tgcggcgctg cccattgttg tactggtaag agaggcttat
     3661 ttggactaag ggacgtggcc catggggaga atctatgtct tattttgttt ccttttctgt
     3721 gatacgctac atccactaaa actacacctg aatttaaaat ctttggagag caacaatgat
     3781 gaaataagac ctacttcccc atagttttcc cgatcaactg accatgcatg ttaactgttt
     3841 actagggcca cctgtgaata gagaaattga catatcgcgt tgctgagtag caatacatat
     3901 ccgacatttt ctgactacca tagccataga acagagtata atactttcct ttatagacag
     3961 aatatgaatg tattcacaat agtttaaatc cagtagaata ttgcaacaca tgactatgaa
     4021 catgataaag caacccacaa tttaatcaat caagttcgaa gtatataaat ttatatcctt
     4081 tattagccat cagtgccctc cgtacataga atataagatg atatctagga agatcttaaa
     4141 atttagtata ctgttatagt gtctagttat aaagaataag aacagacttt gtgaagagaa
     4201 aataattaac aatttttaag atttttttat gacttttttt tcttacggaa tacatatatt
     4261 ttcactttaa aagtttgcgg tcttaaaatt gtttacctat atctaaatta cttagttaag
     4321 actccttaaa ttgactgtag tccaggacat atactagatc ttgaactcga acccaaccca
     4381 ttaacaactc taactgcacg tatttaattg acattttcaa taactattgg gatcctgccc
     4441 tcagcatccc gaaccatatc acccaggcca tatctggtgg tagtcaagct acaaaaaata
     4501 gatcagtatt gttcccaaat taatatgcta tatttttaga ctgacaacat acctccacaa
     4561 gaagttggcc atttgattgt agcgacatcc aactatgtaa ctagcgacct cgtcaacctt
     4621 ttccgggtga gtgagtttga tctcctccaa tagtgcatcg gcaatttgat caaagcgctc
     4681 gatattccga ttgatctctg cttcagtctc cttgactgct tgccggacgg ttaatccacg
     4741 agcactaacc aggacaggga ccatgctgtc aatgtcaccg tgcttctgta tgaagaacat
     4801 gcgttagaag aagataatag tgctcaggta tttttatatg atgtagacgt acgatctctt
     4861 tgcgcagtga caggaggtca ttagatagcg acatgttcat gttcacctcg taccaaagcg
     4921 aaatcatctt cggatcggtc attatgtctc gtgggatatc atttccatcg gcaaatctgc
     4981 gttgtgaaaa ggttagcggc gtttcaatcc tagtatcaga gcgccaccat actcattgag
     5041 agccaacatc gaggtaacag cactggttcc cattcgcgtt tctaggtatt cggcgacgat
     5101 aggaagtcgt ccagtcaact tgcgcttttg ctcccgctgc tggcagccca tataataatc
     5161 aatttcgtta acaaaggtca ttatttgatc tgtcatgata taatatggat cagcccaggt
     5221 cgcaaaataa ctgcataaca agacaccggt acgtaccatg gttatagacc ttctgtagat
     5281 gtgccccgat cacgtccaga ctccgaatga gtgggcggtt cgggggattg ttctggaagt
     5341 cccacttggc ggtttcgtca tctcctaccc caagacagaa tttgacgtat tctaatgact
     5401 ccttccggaa atcgttggct ttgtggatat ggataaaaag gtcagaggta gactggtcga
     5461 tctcgtcgtc ccatgtgaag agccaaagga accaaaatgt gcaggtctga agacggtctg
     5521 ccgtggcacg cggccaccac atggaggaca acagggcgta gtcatcttgg atcagctttg
     5581 ccgccttctt agggggatag agactacaaa agtcagcatg gtcaaagccc taattgcgta
     5641 atggtagaaa ctgcacttct tgattcgggc ttctaaggct acctttagcc cggggtaatc
     5701 aggattcacc gccgtgggcc aggctttata gtacggctta agattcggga ttgagaaggg
     5761 ttctttggtg agcttggcct tcaaagctgg ccggggattg acaacgacag attgagacat
     5821 ggtaaccgaa tacgatggaa gagtgggtag aggcaggatg acagtcgaca agtcgaaccg
     5881 gggttcttgg ttatgttctc attgcggtat ttggttaatt atatagcgat ccgagatgga
     5941 acgatatcga gagaatctga ctgagtatgc tcggggttac agatcctgca atcagccatt
     6001 gacagatttg gccaccttca tcggtgcgcc tcttatccaa gcaccgcaaa tggaccgctc
     6061 taagcccaag cagtcaggga ctgaaacgct gagccatcca cggtggcctg aaatggcgag
     6121 cattggctgg atactggggg tttgaaaaga atagcagtgg acctacgtca tgcctcccat
     6181 tcgaagtgtt gaagattgcg cttgtcaaag actcagctta ggccctacct tggaactgta
     6241 catacatgag ggctgcttag ggccttaatt aggccctcct agtggggcca tgttatttag
     6301 cactcgggcc tgaaaaatcc actaatatca tagctgggaa ctggcgctgc gagggaatca
     6361 tatgactttc gactacccta cctaaaatat caagattact agatgccttg cactatccaa
     6421 atgaccttga tgatctgaat acattgtact agtacagtag tactgcatag attacctatc
     6481 tagactgcct aaatgggttt agattggtta tgtataatgc ttgcttcgct tcgctccgcg
     6541 caacgacact agggcttact ctggacccaa ttttaatgtt gactcaattt tggatcagac
     6601 ctcctcaata cgcagcataa caagggatga acttatcagg atttgatttt ttatgtaatc
     6661 ctatcaaagc agccccctcc cctccaactg caaatcaaat ctcgccaagt cgagccattt
     6721 gcgcgttccg accatagggt ggatttgtcg agttttaggc ccattcacgg cctctgcact
     6781 tgccccagca tggaaagagg gatgatttcg ggaggatggg cgaacaggct ctcctcagtg
     6841 gcgactcgcc gaagctccgc taatttcgga ttctgtcgat gttgatggag agcttcctga
     6901 ttcttgtatc tatacatgtt gtttaccata agcaactcac tccagagatg ctagctatgg
     6961 tattgtagga ctaccacact accaccgtgt ttgaggtagt tcactagata gaaacttact
     7021 tctcaaggac tatcatgatc ggctcccctc caggcctgga accaaagaaa acttggtact
     7081 gcaacgcatt gggttcgttt tcctgcatgg aggcgatgat accgttcatg atttctttca
     7141 actgtagtcg agatattcac attagataat tctagaggaa actcatttgg taaagcttac
     7201 ccggtctgct ttcccagctc gtgggtaaac aatggcgcac tggacctgtt cttgtgattc
     7261 tcccatagta acaatggaaa tccgaacaag atgtaatgcc ttatggagaa gaaggatgac
     7321 caacgagact gcgttgtcag acctgcggga tattaatatt tatccgtagt gtagaagaat
     7381 tccgctctgt tggttcggcc cacgtatgcc tgaaggcttt gcccacttcc aacgaattaa
     7441 gaaaagggcc agtttcgctg tgcctactct ccagctaagt cgtccctgtg ttttatttca
     7501 caagagatgc agcagaatat gattatccct agtttttgga ccggtaccgc cattatcggc
     7561 ctggtcgcgt gcgcctatgt gtcctaccaa tgccttctct ccccgctagc gagatttcca
     7621 ggtccttttg cggccaaact ctcgaagggc tggagggcgt ataagacagc aaatggtcaa
     7681 tggcatcgca agcttgtcga ccttcatcga aaatatggac atgtggtccg cattgcgcca
     7741 aacgagctgt aaaatctcct cgccccttgt agttgagacc gacctaacat cgactctgca
     7801 ggagtgttgg cgatcccagc tcattccgga agatctacag tatgtgcagt accacttgct
     7861 ccgcacttct ggaatgctaa cgaggtccgg cagaggccgg gaatgggttc aacaaggctg
     7921 cgtgctatag cgtggttcaa ggtaatcggc cgtttgattt aactggagaa cgcaacgaaa
     7981 aggtgcattc ggagcagcgc aagctggtag caactgcata ctcaatgagc tcgatggtcc
     8041 attttgagtc caaggtcaat gtagtaatcg agactgtgat tcacaaactg gaggcacgat
     8101 gcaggaaaac gattgatctg ggacattggc tgcagatgtg ggcgtttggt gtgttcaccc
     8161 atttattagt tcctcttcgg acatatccat cccatggcca cacgtctgag aaccaacaag
     8221 gccactacta aactctctca aaccagatgt tattggatcc gtcagctttt ctcagccatt
     8281 tggatacgtc gagagcggag atgacgaggg cgtctttaaa cgtatccaga atgcaatggg
     8341 ctcggcagct tggttaatgc acgccggttg gctgtttaga ttgcaccaga aattgattcc
     8401 aatctgtgga aactggctgg ctgttaatga tcgcaacggc tacttcttcc aggtcgcatg
     8461 cagggaagta tccggacgga tcaatcgcgg cggtgacgac aaggacatca tcggacagct
     8521 tctagagacg cagaaaatca agccacagct gaaagacttg gacatttctt tcatgatgac
     8581 atctaacgtt tttgccggat cggacagcac gtccattgcc tttcaaagta tcttttactt
     8641 gctacttact caccccgctg ctcatgatcg gttgatgcga gaactgcgtg agagggagga
     8701 gaagggagag ctgagcgatc cggtttcgtt tcaggaggct gaatcctggc catatctaca
     8761 ggcaatcatc tatgaggcca tgcgactgta tgctccagca gcctttgtct tggatcgagt
     8821 tgtaccccca gagggtatga tgatcgaaga caagtttgta cctggaaatg tgagctgccc
     8881 cttttttata tttacgagag acctatcgtt ctaactctat agactgtcgt gggatcaagt
     8941 gcttgggtaa tccatagaaa ccctgaaatt tggggcccag atgtagacac cttccggcct
     9001 gaacgatggc tcgatgacag gaaagatgag tatagtacgt ttcttatcta gctatgccca
     9061 atatcagtat atttgtactg acaagcgtta cccgttgcag agcggtactt cttcgctttc
     9121 ggtggaggct ccagaacttg cattggcaaa agtatgtgtt cgtccacggc ctatatatgt
     9181 ttcttaacta atgtttgctt tagatatcag ttggcttgaa atagggaagg tagagatttc
     9241 ctgggatgtt cataaatttg acttcttgag attcgctaat cagacatttc ttagttggtt
     9301 ccaactctac ttcggcattt tgaaatgaga ctcgaaaatg gtgcagtgct gaaagaggag
     9361 ttctggtagg tggaccttgt gcttggagtc cagactgaag acgctctaat ttgatatcaa
     9421 tagcgctctt gttttcctca aagggcttaa agttcatatc tcacgtcgaa gggtttagag
     9481 atatactgga ctacacatgt ttgatatgag cgagatgagc ggcggtttcc ctctgtcttt
     9541 ttgccgtaca tagtcataca gtatttgata cgtgatgccg tttgtctagc gttaatagta
     9601 aaggatatcg tcgtttcttt ctctcgaagt ctgttgtttc tgagaacaca taatagaatt
     9661 atggccacac cacactactt tgctggcatc tctacgatca ttcttcattt tcttcatctt
     9721 agtaggttgc agggttgatg cattcagaaa aagacatcca ctcgatagaa aaattacaat
     9781 aacagctagc ataaacttct tccccacaga gaattatatg tctaactctt cacagggtgc
     9841 aagttcaccc atagaggggg cttaacccag aaagtgaaat tcttctgctc atcccaatcc
     9901 ccgcacttcg gattcaactc caaatcaaag tgataaacga gtttagccag cgcaagctta
     9961 atctcctgat atgccaagtg ccgaccaaga caattccgag gaccaaacga gaaaggttgc
    10021 agagcgcctt tcttatcctt gctatacatc gggtcaccga gccaccgctc aggggcaaac
    10081 cggtctggat aggtgaagtt gctcgaggcc cggaaagcgg catacatggg catcccaaca
    10141 ccgatgcctc ccgggatgtg ttgatcgttc agcacgatgc cttctttggg aaccatgcgg
    10201 gtgtggtttg ccggggatgg agggtagatt cgcagacatt cttccacggt ggcgaggaga
    10261 tacttgcatt cggatagacg ggccacggtg atctctccat cattgacaaa ggtggtgcgg
    10321 atttccgtag ctagtttttg gagaaccggt gggttcttgc cgaggtgaaa tgtggcacct
    10381 atgaaaccta tgttagctac tgggtacaga tggtgcagag tttgctatac cggcgagtag
    10441 agttgctgtt gtttcgctcc cgccgatggt gaggatgttg gcgtgttctt ttaacacaga
    10501 gtagggaatg tcgcctttct tgtagagggc gatcatacgt ttcatgacat cttggtgttg
    10561 tggctcgtgc tggaggcgat tctgtagttt accctggagt ttaatctgta agcactagca
    10621 tattggatgg ggatatgggg aatcgctacc tcagtgagat cgcggtgtag agcgacctgt
    10681 cttttcacgt tgctaggaat cgcccattgc ttgtatatct tgtcgaaagg gaacggcaga
    10741 tgacgggcag cctgacccag ggacatgaga atggcaacgc acagcatagc ttcaatccaa
    10801 tcatgaagct tggagctggt caagcaatgg aactcttcac cgtatgctgg aataatgtga
    10861 gtcaggagag ctgatgcatt atctcgttat acctgggaat gaaaatactt agaaagccga
    10921 taacatcgaa ggtaagatac tatttttagg ttagttctgg tcgtccaggt agtataaagg
    10981 gagaaagagg cagcctcaca ttccattgat ccgtcatatt caactctctc gttccctccg
    11041 cggaggtctc cttcaatcgc tggacaaaca agtcgacaaa atggtgaaga atatgctctt
    11101 ggtctttgag ggatttttcc gagaacgagt tggacagtat cttgcgataa aaggtgtgct
    11161 catcccagtc tccggttaag atggtaggag tgggcttcac ggtgtcatga tatcgcgggt
    11221 ctttaatcag ctcacggtag tcctttccaa gctgatggcc gtagattgca ctccagttct
    11281 cgggctggat gaaggacagt tcgtctggcg cgattcgaac gacatcacca tatttttcat
    11341 gtaacttcag ggtgtcctgg gcgactgttc cccgagcgag tgagcgggca taccataagg
    11401 acgacgctcg tcctaagagt ggcccaggat atcgagccag aggatggaaa tagaggttgt
    11461 acaatcctac ggccagatag aacaggctgt actaaattcg ccacaagcag tcagaggtga
    11521 gtgggtggtg gatctgttac tctagtcttc aacatacaac gacaatgaaa gcgagagata
    11581 gagacaagag gatccattga aagccccctg cgctgaacag ggcggaaatt gagttcattt
    11641 cggtaggcag gagcaagacc aagtaggccc gatcatacgg aatatggcag gcttgacaac
    11701 aaaaagagaa actctcaaga tattcttaaa acagattgct acaaaactag cagaaaagga
    11761 tgtcaaatgt cttgctaaag ggctaagttc cgaagattac tgcggcaaga aatgcctgag
    11821 agaagaggat tccaaccatg aagatatacc gtattatgcg ccttggcgtc tttttagtgc
    11881 agcggcactg ctcgatagag gatttctaaa cagtactatt agttggttaa tttggacagc
    11941 ataagaccta ctggagcatt ggtaaggagc cacggcaaac acgctggtag gggctttttt
    12001 aaggccttcc aggcccactt cgcggtggag aagcagatct tactcaggct ggcctagggc
    12061 agttcatgca gcattcgcct aacaagatta gttcggatag attgaatgga gctgataggg
    12121 atttggtatg gcatgaaata aattgggtgc catccaacct cacccatttc gctgtagtaa
    12181 ggaattttta taaacgttac taagatctag agcacccagg attggaagca aagagataat
    12241 atctagcatg cgcttgctgg ttaaaaatta gtaagcgatc tatggaccca cgatacgccc
    12301 aggggttgag tacgagtact tggctaacta taagtaaatg tacactatgg accattttaa
    12361 tctggcaggg ccggagtcga atacgagtat aacgagcctc gaatggctgg gtatcaagaa
    12421 ctcattcact ggctcccatt gggcacacat tacgggtctc tcggagcttc atccaacagg
    12481 ttttctttgc ttgatagcca cattgattat tggcattgtt cacttgacca ggggccccaa
    12541 gcctaccgtt ctgcctgttg tcaatccccc cggtacattt gagctgacag cgaaccgagt
    12601 aaagaaggaa tggctagtag atgcaaggca gattatccgg aggggattcg aaaaattccc
    12661 tggaaaacca tttaacatga tcgctgctga tgtgggattg acaacggtcc tgccaccaga
    12721 atacgccagt gaaattcgaa ataacccaag ccttagcttt gtcgccttca tggctcatgt
    12781 aggaatatat ccactcctct atgggcatcg tcgagtatta catactgact aggtcaatta
    12841 gttgtttttc agcgaactgc ccggatttga gcctaccagg gaagggatgt ttgataatga
    12901 tattggcatc accgtcgttc ataagtatct cacagtaaat ctaggtctgt cgttcatctg
    12961 gataggcagc tctggggtaa ttgctcacgg actatcggta tagctcgaat cactgaacct
    13021 ctgtcacggg aggccacggc cgcgttgaag gatatattca ccgacaattc aggtgggagc
    13081 tgattgatct ctccaagtcg aagcaaacta actgtgaatg agcagaatgg catgatgcca
    13141 atttgaaagc catcaatctc gccttagttg ctcgattgtc gtcccgcatt ttcctgggag
    13201 aagagctttg tcggaacgag gagtggctca aaatcaccgt taactacaca gttgacgtga
    13261 tgaaggcggc agagagactc cgcagagtgc ctggtccgct tagacgcatt gtccactggt
    13321 tcctccccga ggcccagaag tgccgcgatg aagtcaagcg cgctggaaag gtcattcggc
    13381 ccgtgttgga aaagcgacgg agagagaaag cgacgatgga gtccgagggt aaggaggcct
    13441 tgcagtacaa tgatgccata gaatggttcg agcagatggc caagagtcaa ggtacctcct
    13501 atgacccaga ggtggtgcag ttgtttcttt cgaccgtggc catccataca acctcggacc
    13561 tgttgaccgt ggtcatggcg gatctggctc gcaatccaga gataattgag ccactgcggg
    13621 aggagatttc ctcagtactc cgagacggtg ggtggaagaa gacgtcgttg accgatatga
    13681 agcttttgga tagtgtgctc aaagagtcgc tccgattaaa gcccattgct gttggtcagt
    13741 gcttccctgt atacttaagc gtagtgatac gctaatcagc ccgcacagtt tccatgaggc
    13801 gggtcgccat ggaccatctg aagctctcgg atggtacgtt cctacccaaa ggtaccaaga
    13861 tggctgtttc gtcgcaccgc atgtgggatc cggatgtata tgagaacccg gaacagtggg
    13921 atggctttcg atatgtcaat ctacgcgaaa ccccgggaca ggacaaacat gcccagtttg
    13981 tgtcgacaag cgagcgccat ctgggctttg gacatggtaa gcacgcctgt cccggtcggt
    14041 tctttgcttc tagtgagctt aaggtcgcgc tgtgccacat tctgatgaag tatgactttg
    14101 aactggcccc cggaacggtt gtacagcatc gctactcggg ggcatcgtac tacgcagacc
    14161 ctgccattcg tgtgatgctt cgaaggagaa atgtcgcatt gccttcttgg tttgagcgat
    14221 aaggaaattg gaacaccggg agattttatt gttatggaaa ttgacacatt ggatcgtaag
    14281 gagatcgaaa agtaacagta atagtggacc aagtgtccgc ctcttatctt gtctataatt
    14341 tgacctgcca cctcgtccgg atatactctc cataccgata gatcgcaatt agcaaagggt
    14401 taaataccaa agccatgaac gccaaaatag aatttcccca tccgaacccc agcgtgtcat
    14461 acatgcgctg cccggccagg ggcaagaccg caccgccaat ggaccgaaga acagcgttcg
    14521 cggcgatagc agacgcggca taagttggga atgaatctac caagtagctc accatgggca
    14581 taaagaagaa catattgccc aggccgacaa tcccagagcc aacgataggc atcatccagt
    14641 gtatccgagc ttgcacgctc cagccatacc agaagagccc agctgcaatg actgggcccg
    14701 agagaatcat catgggcagt cgatgctctg gcttggccga cccgaaccgg tttgcctgtg
    14761 ccaccatata ccggtcgctc gtcattgaaa agatccagag gccgacgagg ttcccgatgc
    14821 cgagccccag ataaccaagc cccgatatgc caatcgagaa gtggtatgta tcttgaaaga
    14881 cgggcgagaa agtggtcacc agcacgtaga gaatgccgta aataacggca cagcataacg
    14941 cgacgatcag ggaaatgggc gacagcagaa gcaacttaca cgggcgaacc aggctgtaga
    15001 agaaaattgc aaaattaacc gagcgatgcg tcacactgct gtgtacggtg gtcttccgca
    15061 gcctctttgc tctacggttt agaatggtca tcgcgtatgt ctcacgggta aacagaatct
    15121 ggcaaatggt gatggtacca ttctgagcct tgttaatccg accttccctc ctcatcgtct
    15181 atagcagggt gacttgagga tgactccact taccacaatc gtcaggagcc agaaaaccca
    15241 ccgccagccc aggttctgag tcaagaaccc gcctgcgaca ggcccgatgg ctggggccac
    15301 agcctggccc agcgtcacaa aggagagcgc aaggcctcgt tggtgcatgg gaaatagatc
    15361 cgcaactgtt ccgccgccga tggtgagagg cgcagatcct gtgacgccag cgaagaaacg
    15421 gaagacaatc agcatggaaa tgttggtcga gacaccgcag gcaacagtga aaatagtgta
    15481 gaggatgtta aacacagtgt agcaaatcca gcggccgtac atctcggata tgggggcggc
    15541 cagcagaggc ccaaaggcga gtcccaggac aaaaatcgaa acgacaattg ttgtcaacag
    15601 ttgattctcc tcgtgaaatt cgtgagccag ctcgaccaca ccgggagcaa agatggatga
    15661 ggccagcggg cttttctctc tcgctctgta tcagcgactg cgcagcactc cgtcgtttgt
    15721 agacgggtta actcacattg taaaggttcc aatggaaata atagccacat gcacccattt
    15781 ggccaatggc gaccaattca atgggttcgt ggggtcgtcc tctccttccc aggagacgac
    15841 attgtcttga ctctgctcgc tgtcgtggtc cctgggccta tcggctttac ctgctggcgt
    15901 ttccatcttg tggctggcta acttgttgtc gcacacttca gacaattcag agaggccgta
    15961 aatcactgcg gtctgcgatc tctaagatct ggcgcaggta aacatttatc gtagggaagg
    16021 agaaactttg cagaattagg aacagacttg cggcgcatga aggaaagaaa aggtttaatt
    16081 gacctcctaa aaccccagtg ggtcattata agcactgacc ggccgcctaa agtcggccag
    16141 ctgcaagaga gcgctgatca ttggaacggc taaagagaga agactcgact gggcagtgtt
    16201 cacttatttc ctttccttaa aaattaattc cctcacctta tttgactggg gacaagatct
    16261 ccgcagactg gactatttac tacgagtcaa gatagatgtt taggtttaca attaagctct
    16321 tcatttcttt cattatcttg cgaactacga caatgtccat atcatcaatc atgaccctac
    16381 ttcccaacac tggcaatgta ggcagtcagg tctagcaccc gccgactgta tccccactcg
    16441 ttgtcatacc agctcacaat cttgaggaag ttcgggttca aagagatacc agccttgata
    16501 tcgacaattg atgaatgagg gttccccttc atgtcacttg agacaacatc atcctcggtg
    16561 taatcaagaa tacctactca tccttagtta tgctatcaaa ccagagccac agtcagctta
    16621 ccctttaatt ctccctgtgc agcttccttg atcgcagtaa tgatctcctc ataggaggct
    16681 cctttctcaa ggcgacaggt caagtcaacc acggacacat tggaggttgg cacccggatc
    16741 gacattccgg tcactttacc ctggagctca gggatcacct taccaacggc cttggccgcc
    16801 ccggtactac tcgggatcag gttctgagca gcagcacgac cgccgcgcca gtccttcttc
    16861 gaaggtgcat caactaactt ttgcgtagca gtataagcat gaaccgcggt catcaggcct
    16921 tcaactaccc caaacctctc atgaagaact ttagtcaacg gcgccaggca gttggtagtg
    16981 caggaggcat tcgacaccac atcggcccct gcataagtct tctcattcac ccccatgacg
    17041 tacatgggtg cgtcggcaga aggggcagag ataatgacct tcttggcgcc accttgaagg
    17101 tgagcacttg ccttttccac agtagtgaac acgccggtcg actcgataat atattccgct
    17161 ccagcatcct tccatggaat tttggcagga tccttttccg cgtagaactt gaccttcttg
    17221 ccgttgacaa caatggagtc accgtcaatg tgaacatcat attcaaagtt gccgtgggta
    17281 gaatcgtact tgagcatgta tgcctaagca accgacagat tatcagtaat catgtccatt
    17341 tcgacatcag acccatccaa gggacatata ccgcgtattg aacctcgata aaaggatcgt
    17401 tcaccatgac cacttcagtg ttttcatggg agaaggagtt gcggaatacg atccgaccga
    17461 tccggccaaa gccgttgata ccaactttag cggtcattgt gttctttggt agttttggct
    17521 tgcaacagga atggaaggcc ttgatgtggg tggaaatgac agtggaggat acgaggccac
    17581 ggacgaaggg agacagacag ggtagcgagg gcaggatttt taacccctct cagatactcg
    17641 gtcttacgac ctccgaacat accaccctcg gacaatgacc tcaagtagca gagtctacta
    17701 tgtacaagga tgcctccggt gtactccgta gagaccaggt agagcctgtt ttctccctgg
    17761 tagtcggtag ccactactag ccggatccag acaccggctt aaacatgcgt tatctgcgcc
    17821 cagtgagaat atgctccgta ccttggttca ttaggtcgag atatgcacct agggacgact
    17881 agtggcgtaa ctaaccctat ggaggtcata atagtggcct actaagtaag acgcccaact
    17941 tccgtcggat cagcccgcgg aaggcctaag aagtggggac cgaagagggc ctaagaagct
    18001 tagccctact tagtatgcta tcaccagtgc tactatagcc tttaggccac gcactgggcc
    18061 accaacagga ccgaggatag aaggaagagg tttcaatgtg gtctcctaga cacacggagg
    18121 atcatgaccg gcaatgataa aagtcgaggc tgaaagtcct ggtgggtagg ttcgatacga
    18181 tgtagttgta aaagagctgg tttcgccatt gttctggtcc tttaacgacc agtacataca
    18241 atggcttcct taacaggtgc tgctgctgtt ttactagcgt tcattttagc ctattcgacc
    18301 gcgctcacca tttaccgtct gtttttccat ccgttggcta ggtttccagg accaaggctg
    18361 gcggcggcaa caaaatggta cgagttctat ttcgatatca tcaaatcacc aggtggtcag
    18421 ttcttcaaag aactcagtag gatgcatgat gtttatggta cgtcagagta aaagcctggt
    18481 gatatctcct gatcaattaa ttgatcatct cccaaggacc gattgtccgg gtcaatcccg
    18541 atgagattca cgttcgagat gcagcctggt tcgaagttct gtacgcgccc aacccgacga
    18601 aacgcaacaa atatcgtcct tcggcggaga tggcaggact gaccctcgga agtatgacgt
    18661 tgcatttgta tatatttttg gttcatcctt cattaactcg gcttgacaaa agtccacggc
    18721 acagttgacc atgacctcca ccgacgacga cggatggcga tcgccccaat gttcaacaaa
    18781 caatccattc tcagtgccga acatctgatc aaacaacata tcgacgagct gaccgatgtt
    18841 tttgagtcat atcttgggac caacaatcca atcaatttac agaccacctt cttggcctac
    18901 actactgatg tcctgtacca ttacatgttt gatacagatg cgggctacca acgcgactcg
    18961 ggggccgctc agcaatggag gcactcgatg gacgctgtcg cgcaagctac ccctttcttg
    19021 aaacaattcc ccagcctcct gtcaagagta gcattaatac cgcttcctat gctgatatgg
    19081 gttctcaagc ggattcaacc cgacgttgct ggattactgg gcacacatca agtaggttgc
    19141 ccccgtgttt tgtagacact ggaggagagg ctgattgagt agctgatggc aagcattgta
    19201 tcaaaataca tggcatccaa acccgaagag gatcaagacg aactgatagc aacgaaggct
    19261 gtcaagcccc gtaccttatt tcacgcgatc gaagcgagct ctttaccacc tcacgagaag
    19321 gctcccactc gtctggcgca ggaaggtcta accgtcctat ttgcaggtgg cgagacaggt
    19381 tcacgtctgc ttgcccacac agtataccat ttattgaaga atcccgagat tctcgagaag
    19441 gttaggaagg aaatcctcga cgctgcagga gactccaacc aactgcctga catgaaagct
    19501 ctcgaggctc tcccttggct tgtacgaagc ctctcaccta aggatattgc aacggggaca
    19561 ggctgattgg atatagactg cctctgtccg agagtcactc cgccttagag ctgcgactac
    19621 gtctcgattg ccgttggtca ccgaaaagcc attggcatat gctgactggg tgataccgcc
    19681 caatgtgagt gccatggata tcacaacaga agttgcttgg atgtgaatgc taaatgatcg
    19741 gtacctttag acccctgtta gcatgagcca cggagatatt ctacacaatg aagacatctt
    19801 cccagaccct atgaagttca tgccttcacg gtggttcaat gcgtcaccgc agcagaaccg
    19861 cctgttcgtg ccttttggta aaggaacccg tatgtgcgtt ggaatgaagt aagtaagatg
    19921 cgcagatctt cacttccgtt gctgatctat ttggtgatca acagcttcgc ctattgtgag
    19981 atatacatga gtcttgccgt cattcttgct cggtttgatt tagagctata tgacaccaga
    20041 tgggaaagag atgtgcatta cactcgtgac tgcttcctag gcgaaccaga cccggccagt
    20101 ccgggcatac gggtcaaggt tgttgctgac cacaagacat ttactcgttc ttgaaactta
    20161 tcagtataag cggagaagga tagaaataaa taaggacacc gaattctcta agcgagatgg
    20221 tatttggctc tatgcgaatc tgcttttgac gtctcccgta tctgtggtcc gtatcataaa
    20281 aatcatcatg cgagtatacc tcgtcaattt ctatccaggt taaactgaac aagaaagctc
    20341 tacccagagc tacgtccata caggtggccg ctgacccact tctgcgcttc aaagcgtttt
    20401 ctctcagctt cttgcctcga tttcatgatg aatgtctata tcgggaatcg catcggccgt
    20461 gccgtgtgtc tcttgacccg cgtagtggct gttattatgg atcctgcgca catgatctct
    20521 catgttgtca agtctactga acatcctcga acatcgctcg cctctctcat ccagacaagg
    20581 gcattgaatc cttgggtcgt gctttgcctc atgtcgggca cggtctttcc tcgtcgcgaa
    20641 gccgcgctta gtggagggat gagggccctg tagacccggc ccagcctgcg gacaatgcgg
    20701 ataacggcaa aaaaatcgtt tgaaatgttg tttatagtgc cgtcgaagct cgcgggaccc
    20761 ggtaaaccgc agtgtcgact tgcacccagg aaacgggcat gtcacagcac cgggtcctac
    20821 aacttcaagg tcgctgatct gcatccatcg gggctccggg tcggccctat ccgtcaagtc
    20881 aggtaagtga gtggtcggac ccacccttgc aggattcaaa tccgcgggaa gttgtagctc
    20941 acccgggagg ttgtcaagaa gatcaaaggg accgaacttg ttcgtttcgt cgtgttctgg
    21001 agaaggatct ataggtagca gcccggggct cgccatcgac agaacatcac gcgatgattc
    21061 tggagaattt tgacggttaa agagcggaag agccatccat gtttcagcca ttttcagacg
    21121 cggtacagat acactcgatc ggccgtttta ggtgagactc gtgggcatat ataccctggt
    21181 cccctagaaa tatgggaagc acattgccgt gtttcatgtc atccttgata agcagcagtg
    21241 tttttctgtc atcataattg aactgatata cttgattcgc tcaccgatcc ccttatgtgt
    21301 cgaataggac cactgtttgg gagccaaaaa aaaaaaacca gtgaaaggag agcaaggctg
    21361 tgacaagagg cctattcctt tgttgcgcag gtggagtcaa aggaaggcag tggtggactt
    21421 cgcagtacaa agtagtatcc gaagatcctc aaccgatcaa acccggtcgg ttctttcggg
    21481 ccgcaggtgg aatactgatg acccaatatg acctaatcac ggggggggac tagccccgag
    21541 agggtcaggt acatgacccc tgcacactag cacccaatcc gcgtacagac cagctccccg
    21601 tgctcgctaa tatagcctag gatgtactac tataattggt ttagcactaa tacttatcta
    21661 gaatagcctg aaaagaagct cagagtagta ggcggatcag tactccgtac ccgggcgata
    21721 cttcctaaaa agggaatttt ctaattcggc aatttggttt ccgacaccta ctagtgctaa
    21781 cttccgacaa tgtgactccc tctatatact agcactgtaa gatcctgata tagatataag
    21841 ctctgtattt aatcaatatc aatatatcat agaacagcaa gcatatttta tagactaggg
    21901 tctaaataag tgcgtggctt aatgtaggta agaattggct cttgtccaga accttgattc
    21961 agtcctccgt aactaggcag aagatactac tagtgtatac tctgcagtct ctagtgagca
    22021 gccccatccg ccattcgtca ccccgatatg gcggcttact tagtagagac gactataagc
    22081 accaaaagta ccatgcttgc tacgccaatc tgacaaggca agatgacaaa gcaaacccct
    22141 gattcgccca atcaactgtt tatcatccac aggtgaaacc tggtccagac cttggatgac
    22201 ggctacagcc caccagctca atgtgaagaa tctaaatctt gactaatcct atggccgttg
    22261 ttacccctcc aggttaccta cacggagaca ggagtacata ccttgcactc gagttatagc
    22321 ttcctcgata tatcagtgat tgatttcttg atatcttagc aagttctgac ccactatact
    22381 catttcgtgc aatgcccggg atcgggcgta gataagccat ggtctcggtt gaacgggggt
    22441 tcaggaaatc aaggattaag tggacaaggg tttgggaaat cctcagaatt ctccctgagg
    22501 ttataaaccc cgttcagccg gatgtgtgat ttattcatcc tctaaagcct gtacggcgcc
    22561 caaccatgtt cccggataat taaagtaccg tgtctggagt gccagaaata accaaaggaa
    22621 atattgaaag tatatctcac caaaatgatc tcaatgagtg tacctaggaa aaagcaggag
    22681 agggaaatca gccttctgat gcattatgtg gacgacgtgt ttcctcatca attccctatc
    22741 tatcatagcc agtttgtggg gaaaagagaa tggctgttgc ccttgctctc ttcaacgaga
    22801 tcggtctatt acgctacgct gtgcctcagt ctactgcaca aggagaaaag ctccaatctg
    22861 gaccagccag ggtcggtatc tttctgtcaa gaggagagac tccgatatta tatactggcg
    22921 ctgcgagaga cacagcagct tttacagcag ttgagcccag tatgtgacct agaagccatg
    22981 agatcctgtg ttccttccct ggcaagcgct ctacatctga tcagttatga ggtaaagtag
    23041 ccctttctcc gacaggatac agtgactttg tacgttaact tggctacctt agtcttcctg
    23101 ccctgtatac ggggattgga aagttcatct acaagctgca acatcactga tccctattct
    23161 cgtagggggc tggaacagta tgattaaacc tatcaaacat acttccaccc tttggacagg
    23221 tttaaccctt tctgatttcc atgacctcca cacagaaggg tccctctctt acgaagatgc
    23281 cagcgcctta cggtttctaa ccaatgcact agctgtaact ggcatcctct cgttcatttc
    23341 aaccggcccg acatctgcac tatccgacta ccgctacctg atggatgcca catgcgacat
    23401 ggtccagtgt gaccagttcc ttggttgcga gaactgggtg atgtcagcta ttctagacgt
    23461 aggcctactg gaccggtgga aaagagaaga ggaaggtaac cgacgcctga gcttccggga
    23521 actagcaaac cgggccaaga gactcgagga ctgtctggaa aacggcatca gagagctatc
    23581 ggccaaaacg tccggctctt cagatgcagt tagctccatt acccgcattt atgccagttc
    23641 caccctgacc tacctccatt cggtagtttc gggtctcaac ccggacctaa gcgagataca
    23701 ggagagtgtt tctcggacca ttgagctcct caaagaatta tccaactggc atcttctcgc
    23761 ctgtctgact tggcccctgt gtgtgactgg atgcatggca gcaccggatc atgaagcctt
    23821 ttttcatagt ctggctattt cggcggagat tagtccgcat tcgttgaggc atacttggat
    23881 tgttttacgg atattaaagg atgtgggcaa ggttcgcggc tctttggggg aacagatatt
    23941 gcccacatgg gaacagattc tttgtattga tggagctcca atactactta cataaagatc
    24001 gtctaaaaga agctggggta tcttttacag tctcattcaa aggttaattg acttcacggt
    24061 aagcctttgt gaggaccagt accaaagcgt agcagtccaa attcttcctg aggcgctgat
    24121 gaatggaggc ccaggattta gttgaggctc gagggttggt cgagtttctc acaggtccag
    24181 actatgacag ccacattgta ccagacttac tccgatatag gatccagagt tcgatgtgca
    24241 atccaattca gaggactatg ggatacacct ttgtaggata tcagtatgat gcacaatctc
    24301 ctaatgctta tgtgatactg tatctagtag taaatcgcag attccagttc aggccatcat
    24361 ttctatccta agggcgattg tatctaggag aaagagaaca aggacaggat gaaaatgaat
    24421 catagaacag agggcggccc agaatctacg tgtcttccag ccatcttgtt acgtatcgta
    24481 cgagaccctc aagggacaaa atatgaattt acccgagata cttctcaaag aagtctgcaa
    24541 cctgggtgta cctgttccat aggcgtcagt aatcactttt cgagaaagaa catgaagttc
    24601 ctcttaccct cgtcggtatt cagcattgct ttcttcactg tccagattag cacgtgctcc
    24661 catccagcca tgccacatgg tgctgtatgt ctcgacgtgg ccaccgatac cattcgtgct
    24721 gatgacatcg gcatagcctt ggatttcctc cgctggctca tctttggatg caaggacgat
    24781 atgaggaatt gtaagtttct cagcgtctgt tttgtcagtc cgactacaag taagtgaata
    24841 gattcagtat tcttcttttg tgtatatcag tttgaggcca tacataccca ggatgaactt
    24901 gcgcagtagc tacaaacggt gtaccgggtc cagaagctag aacagcaacc taagaagtac
    24961 atgttcctta gttgcgaaga ttatttcgac ccacaataaa aagaatcagc tcaccttccc
    25021 accccagcac agtcccaatg cagcccattt ggacacagac ggaaataatg tgttgtactg
    25081 cttagttatc tccagcagag tgtccacatt cctcggaatc gaggcttcat tggagacgaa
    25141 gctcgtaaga gcgttattct tctcttctgt gtccgccggg aaccattcgg gctgggcata
    25201 attcccttcg aagaaatcgg gcaccagaac caatgagttc aatcttgtag ctagaaagtc
    25261 tgccccctgc agggtctgga tggccatgcc gaaaatgtcg taaaggacca caagcccagt
    25321 ggaagcattc ggcggaccag taacatctgg agaaggtcag agcttgttct tcttcttgtg
    25381 tatctgtgtg tgacttgcag gtgttcaggc cggcgacttc tttataggtg cctttggtgg
    25441 tgtatccttg ggagatcacc ggtggtagcg ttcggcatgc gtcacaagac atggtgggat
    25501 ccttcgtagg tacgatggtc ttctggattg ttgtttgtat gaacacaatg tcaagttgcg
    25561 agttagtcgg tcttatacta tgtggacacg ctagtcttcg gagattatca cttaacgccg
    25621 tcgggattaa aacgtccttt ttgaataaag taggctaagc tttggttggc atgcccggga
    25681 ccggccctga aacgggggat cggactgcca cagagaacgt tggttcctta cccatgaagt
    25741 tgacgaaaga aagtcagtat cagtgtgata tacagctatc tctcaatttg acactaccaa
    25801 ctgcaaatcg actctacagt agtatcaatg gcgcacggca accaatcaac gaatgaaacg
    25861 gaagatatta gcccggtgaa ctccataatt cgctctaaag atcagactga cgagacaaag
    25921 gtagacaaca acgaacttta cccggtcgga aatgaatgtg acaagaacga tgacgctccc
    25981 tactgttccc tttctgagcg ccgaaagatc tccgtgatgc taatagcatc attttccggc
    26041 ataatatccc caatatctgc cagtatctat tatccagcac tccccaccat tgcgaaagac
    26101 atgcatgttt ctatctcctt gatcaacttg actatcatga cctatctggt aagtggactt
    26161 tgctatacta gttcaagaac ttcctttatt cagaacaagc ctaatatgta tccagatatt
    26221 acaaggaata tctccctctt tcaccggatc cttttctgat gtctatggac gacggctcgc
    26281 ctacatgctc tgtttcatca cctacatcgg ggcaaatatt ggccttgcat tacagtccga
    26341 ttacgcagct ttaatggtcc tgcgttgtgt ccaggcggct ggtagcagcg gaacgatcgc
    26401 gatcggaagt gctgtggttg cagatatatc gacacgagct gagcgaggca aatacattgc
    26461 atatgccacg atggggacga cactgggacc tgctctgggt cctgttcttg gaggtctcct
    26521 ggatcacttt cttggttgga gatgggtttt ttggtttctt gtcatcttag gtggcttcaa
    26581 ctttaccctc attctcgtgg catgtccaga aacgtgccgt gcagtggtgg gaaacggttc
    26641 aattccccct gctaaatgga atcggccttt gtgggtgata ctgagggatt cactaagacc
    26701 tcagagccat aaggccggaa agagggttga ctatgagact ctggaaagga gcaaaacgcg
    26761 cccgaatcca ttgacttctg ttcgtatcgc tctggaaaaa gagggtggtt tgattctcat
    26821 ctacggggca ctgctatacg ccggttacat gattattctg agcactctga cctcgcagct
    26881 ggagagcgag tacggattta actccatcca ggtgggatta tgctacttac ctatgggaat
    26941 cggaagcctg acatcccgtt ggtccgcagg acctttgctg gattggaatt tcaaacggga
    27001 agctaagcgt caaaacctac ctattgtcaa gaatcgccaa caagacatcc gagacttcaa
    27061 tattgaaaga actcgtctga ctattacaat acctttcgtg tatgccggtt gcctgttcct
    27121 tcttgcatac gggtgggtta tgagattcca gactcacctg gcggttccgt tggtgttgtt
    27181 gttcttctcc ggccatctca ccacgggggc tttttcgacc cttagcacgc tgatcgttga
    27241 tattcatcgc caaagtgcgg ccaccgccgt ggctgctaat aacttgtttc gctgcttgct
    27301 tgcggctggt gcgacagctt tcgcggcacc cctgatcgat cgtattggca ttggctggac
    27361 gactacgttt attgtaggtg tttggattgt cttcagtgcg tgtctgtggg cggtttatct
    27421 ctggggacat aaatggagag atgaattgcg tgttaaacgg agtgagggag atggtagccc
    27481 agcatag
//
