BGC0002000 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002000 (Streptomyces aurantiacus JA 4570)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T2PKS	1	37,332	High	setomimycin	PKS

BGC0002000 - Region 1 - T2PKS

Download region GenBank file

Download region SVG

Location: 1 - 37,332 nt. (total: 37,332 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 37,333
Label		BGC0002000

Tailoring functions

Oxidoreductases: dehydrogenase oxygenase

STRAU_RS10360: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

STRAU_RS10395: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Lyases: cyclase

STRAU_RS10400: cyclase/dehydrase

smcogs: SMCOG1128: cyclase/dehydrase

STRAU_RS38955: Polyketide synthesis cyclase

smcogs: SMCOG1225: Polyketide synthesis cyclase

STRAU_RS41395: Polyketide synthesis cyclase

smcogs: SMCOG1225: Polyketide synthesis cyclase

Ligases: synthase

STRAU_RS10380: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

STRAU_RS10385: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002000.4	1.00	PKS	setomimycin	Streptomyces aurantiacus JA 4570
BGC0000231.5	0.83	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0000234.5	0.76	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001723.5	0.70	PKS	oviedomycin	Streptomyces antibioticus
BGC0001895.4	0.63	PKS	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0002514.3	0.61	PKS	julichrome Q6.6	Streptomyces sampsonii
BGC0000272.3	0.59	PKS	spore pigment	Streptomyces collinus
BGC0002276.2	0.58	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000197.5	0.58	PKS, saccharide	aranciamycin	Streptomyces echinatus
BGC0002012.4	0.58	PKS	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002000.4	1.00	PKS	setomimycin	Streptomyces aurantiacus JA 4570
BGC0000231.5	0.83	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0000234.5	0.76	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001723.5	0.70	PKS	oviedomycin	Streptomyces antibioticus
BGC0001895.4	0.63	PKS	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0002514.3	0.61	PKS	julichrome Q6.6	Streptomyces sampsonii
BGC0000272.3	0.59	PKS	spore pigment	Streptomyces collinus
BGC0002276.2	0.58	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000197.5	0.58	PKS, saccharide	aranciamycin	Streptomyces echinatus
BGC0002012.4	0.58	PKS	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 37332
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Malonyl elongations:: 8|9 (Score: 676.2; E-value: 3e-206)
Product class(es):: angucycline
Product molecular weight(s):: acetyl-CoA_8: 333 Da
acetyl-CoA_9: 375 Da

STRAU_RS10380: KS (Score: 784.1; E-value: 6.6e-239)
STRAU_RS10385: CLF 8|9 (Score: 676.2; E-value: 3e-206)
STRAU_RS10390: ACP (Score: 118.9; E-value: 1.7e-37)
STRAU_RS10395: KR C9 (Score: 470.8; E-value: 2.6e-144)
STRAU_RS10400: CYC C7-C12 (Score: 443.0; E-value: 1e-135)
STRAU_RS41395: CYC C4-C17/C2-C19 (Score: 169.6; E-value: 1.6e-52)