BGC0002002 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002002 (Serratia fonticola)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like,phenazine	1	14,395	1,6-phenazinedimethanol/fontizine A	NRPS:Type I	100%

BGC0002002 - Region 1 - NRPS-like,phenazine

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Location: 1 - 14,395 nt. (total: 14,395 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
phenazine: phzB

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 14,396
Label		BGC0002002

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002002	2.00	NRP	1,6-phenazinedimethanol, fontizine A	Serratia fonticola
BGC0000343	0.62	NRP	enterobactin	Pseudomonas sp. J465
BGC0001527	0.56	Other	basidioferrin	Gelatoporia subvermispora
BGC0002476	0.52	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0000936	0.51	Other	pyocyanine	Pseudomonas aeruginosa PAO1
BGC0000328	0.48	NRP	coronatine	Pseudomonas savastanoi pv. glycinea
BGC0002493	0.46	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0001868	0.45	Other (Phenazine)	iodinin	Xenorhabdus szentirmaii DSM 16338
BGC0002020	0.45	Saccharide, NRP	photolose	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002474	0.45	NRP	agrobactin	Agrobacterium tumefaciens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002002	1.00	NRP	1,6-phenazinedimethanol, fontizine A	Serratia fonticola
BGC0000343	0.64	NRP	enterobactin	Pseudomonas sp. J465
BGC0001527	0.62	Other	basidioferrin	Gelatoporia subvermispora
BGC0002476	0.59	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0000936	0.59	Other	pyocyanine	Pseudomonas aeruginosa PAO1
BGC0000328	0.57	NRP	coronatine	Pseudomonas savastanoi pv. glycinea
BGC0002493	0.56	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0002020	0.56	Saccharide, NRP	photolose	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002474	0.55	NRP	agrobactin	Agrobacterium tumefaciens
BGC0001868	0.54	Other (Phenazine)	iodinin	Xenorhabdus szentirmaii DSM 16338

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 14395:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

WN53_RS03350

Search NORINE for peptide: strict or relaxed

AMP-binding (28..403): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code(s):: Gly DILQLGLIWK (82% 8Å match)
Stachelhaus code match:: 100% (strong)

WN53_RS03365

AMP-binding (72..303): X

nrpys: Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -MMITGSGEK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)