LOCUS       BGC0002004              9803 bp    DNA     linear   CON 13-APR-2022
DEFINITION  Methylosinus trichosporium OB3b chromosome, complete genome.
ACCESSION   BGC0002004
VERSION     BGC0002004
KEYWORDS    .
SOURCE      Methylosinus trichosporium OB3b
  ORGANISM  Methylosinus trichosporium OB3b
            Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
            Methylocystaceae; Methylosinus.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP023737.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from ATCC:35070.
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 05:54:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1498746
            Orig. end    :: 1508549
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1143)
                     /locus_tag="CQW49_RS07145"
                     /old_locus_tag="CQW49_07135"
     CDS             complement(1..1143)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014890866.1"
                     /locus_tag="CQW49_RS07145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQW49_07135"
                     /product="di-heme enzyme"
                     /protein_id="WP_003614736.1"
                     /transl_table=11
                     /translation="MMRASFLVLAALVLGARSAAEPAPAWNWDLPKYIPPPRVPVDNPM
                     SEEKFQLGRRLFYDKRLSGNGTLSCSSCHLQERAFTDGRTVSIGSTGAKTPRNAPSIAY
                     SGWHGTLTWANPALVTLERQMLNPLFGADPIEMGASDANKAEIVARFRADADYRRWFAA
                     AFPEMSEPISFATIIAAISAFQRGVYSFDSRYDHYLQGEAQLTEAEQRGHDLYFGEKAE
                     CHHCHGSVGLDDQFVHARTREPELPFHNTGLYDIDGKGAYPAPNHGLFDITGDPDDMGK
                     FRAPSLRNIALTAPYMHDGSVATLEEVIDIYSEGGRKIASGPHAGDGRASALKSGLIVK
                     IDLTAQEKADLLAFLKTLTDESLIASPRFSDPWRTPTAAK"
     subregion       1..9803
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="RiPP"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..9803
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1140..2114)
                     /locus_tag="CQW49_RS07150"
                     /old_locus_tag="CQW49_07140"
     CDS             complement(1140..2114)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018265056.1"
                     /locus_tag="CQW49_RS07150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQW49_07140"
                     /product="metallo-mystery pair system four-Cys motif
                     protein"
                     /protein_id="WP_003614734.1"
                     /transl_table=11
                     /translation="MWELHRARTATIAAGALIVAGAALAAGVKTQPVAVRFALVADGKE
                     VGCGAPLANLGSGRLAGKLHEARLYVYGFELVDAKGKHTPIALTQNDWQYADVALLDFK
                     DARGGNAACTPGNPAKNTTVVGAAPQGAYVGLAFSVGAPVESLVDGKPVFVNHSNVEAA
                     PPPLDISGMAWNWQAGRRFVTIEVIPPAAVIKPDGSKSRTWMVHVGSTGCKGNPATGEI
                     VACAHENRFPVVFDRFDPKTQRVELDLTTLFESSDISVDKGGAVGCMSALDDPDCPAVF
                     RALGLNLADSAPGANDAGKPSRPGVSPIFSVGAAASKVAGGKQ"
     gene            complement(2527..3600)
                     /locus_tag="CQW49_RS07155"
                     /old_locus_tag="CQW49_07145"
     CDS             complement(2527..3600)
                     /NRPS_PKS="Domain: Aminotran_1_2 (18-345). E-value:
                     2.9e-42. Score: 136.9. Matches aSDomain:
                     nrpspksdomains_CQW49_RS07155_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 147.2; E-value:
                     1.1e-44)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018268276.1"
                     /locus_tag="CQW49_RS07155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQW49_07145"
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="WP_244441328.1"
                     /transl_table=11
                     /translation="MRAKSSLAVPIFAVAPRPDGILLDSNEFRFPLPKRFLKRVADELW
                     PVDLRCYPDFAEVEKIKVALARDLGVEPDNLLLGVGSTELLDLISRAFGERDHRIVTPI
                     PSFPMYAHYANLNDRKFVPVPLDDDLSLSSKVAEALLREPGSKSFYVCSPNNPTGLSIE
                     RETFDALASDPRAILCLDEAYAEYSGRSFVTEAATRDNVVVTRSFSKIGLAGCRFGYAV
                     ASKNLIRELAKAALPYALNSLTLRIAQIFIEEMPLIRAVVEDVKRERARLSTALANLPG
                     FHPYRSDANFLLCAAPGDAAALARRLIELRKIWVRPFSPQSRLRDCLRIAVGSPEDNDI
                     LLDALRQESTIHAPRSE"
     aSDomain        complement(2566..3546)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CQW49_RS07155_Aminotran_1_2.1"
                     /evalue="2.90E-42"
                     /label="CQW49_RS07155_Aminotran_1_2.1"
                     /locus_tag="CQW49_RS07155"
                     /protein_end="345"
                     /protein_start="18"
                     /score="136.9"
                     /tool="antismash"
                     /translation="DGILLDSNEFRFPLPKRFLKRVADELWPVDLRCYPDFAEVEKIKV
                     ALARDLGVEPDNLLLGVGSTELLDLISRAFGERDHRIVTPIPSFPMYAHYANLNDRKFV
                     PVPLDDDLSLSSKVAEALLREPGSKSFYVCSPNNPTGLSIERETFDALASDPRAILCLD
                     EAYAEYSGRSFVTEAATRDNVVVTRSFSKIGLAGCRFGYAVASKNLIRELAKAALPYAL
                     NSLTLRIAQIFIEEMPLIRAVVEDVKRERARLSTALANLPGFHPYRSDANFLLCAAPGD
                     AAALARRLIELRKIWVRPFSPQSRLRDCLRIAVGSPEDNDILLDAL"
     gene            complement(3677..4987)
                     /locus_tag="CQW49_RS07160"
                     /old_locus_tag="CQW49_07150"
     CDS             complement(3677..4987)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 61.2; E-value: 1.3e-18)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016921440.1"
                     /locus_tag="CQW49_RS07160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQW49_07150"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_003614730.1"
                     /transl_table=11
                     /translation="MTRPKTGFWRGYWPLLMALASAQLAQQADIVMMSRLGGPAAGAYV
                     MMMRLALVEVVLMTAMGAVASTVVAQAQRNGGAAPVIGRILGLALLTGLLCGALGWLLY
                     PTAARWLAGEGDVASLVGEGVFWHALAAPFRFVVNIGAFVLHALGRGPSVVRWKLTEAA
                     AKIAANLLLMDVLGWGFSGCFLSGLIVGALSSIWCRRMLPPGDARLSLPGCSWTLRFLR
                     PIYWEAQRLISVQLAILACFSLFAAPWLANYSVSRMNSFAAGQTLMLMLFTPFVALTRF
                     LAFRHAALRDGRLSASMWRVWAQGAPVVVAAALALLESDELLGRLYGQSGHWWSTLIQA
                     LAISLPLRFAANIARALFHSQGSFAMVAAADGAAFWLIATPLVAIGLYVDSPAVAYSSL
                     ILPEAACAAWMWGRLGILAFREKGPVGADEGVKALLE"
     gene            complement(4984..5571)
                     /gene="mbnC"
                     /locus_tag="CQW49_RS07165"
                     /old_locus_tag="CQW49_07155"
     CDS             complement(4984..5571)
                     /codon_start=1
                     /gene="mbnC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018268274.1"
                     /locus_tag="CQW49_RS07165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQW49_07155"
                     /product="methanobactin biosynthesis cassette protein MbnC"
                     /protein_id="WP_003614727.1"
                     /transl_table=11
                     /translation="MSLLPTAPVRIDADLYDDLANPARQSLYPRDSRGFIRIDISLRAY
                     WHTLFDTCPRLLELSGPSGGAIFLPFMAWARENNLAFDWSFFLWVYVWLQQSEFRERLD
                     EDQLLPVMTASATRWLMIDRDIDACQIVLGSRSLAGAAVVGAKIDSIHCRLEQVQQVEF
                     EKPLPLPDGEFGYFLTPGFEIDHFPGWRPLPR"
     gene            complement(5543..6373)
                     /gene="mbnB"
                     /locus_tag="CQW49_RS07170"
                     /old_locus_tag="CQW49_07160"
     CDS             complement(5543..6373)
                     /codon_start=1
                     /gene="mbnB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016921438.1"
                     /locus_tag="CQW49_RS07170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CQW49_07160"
                     /product="methanobactin biosynthesis cassette protein MbnB"
                     /protein_id="WP_065083569.1"
                     /sec_met_domain="DUF692 (E-value: 2.7e-24, bitscore: 74.6,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIGFNFTLTGTLDMVQQMIKERKIDYVEMLIDNFVHLPPEQIAD
                     SFDCPVAFHIMLSKYLERDREELEKLGKRLRRFIDVMRPVYVSDHILYFTHNGRSLFHL
                     GEIDYREYDHVRSKVEQWQDMLGTRLYLENYPSIMDGAWDAPSFYERLSRETGVGVLFD
                     ASNAICAQNNTGAPVELWKKIIETTRHFHVAGYGTAFIEPRVKADTHDREMAEDTLDFL
                     SRMRTSFDKPGATITYERDFDIDYESISVDLKRLRDIFPCVEEERHEPVAHCAG"
ORIGIN
        1 tcatttcgca gcggtcggcg ttctccaggg atcagagaaa cgcggcgagg cgatcaggct
       61 ctcgtcggtc agcgtcttca ggaaggcgag gagatcagcc ttctcctgcg ccgtcagatc
      121 gatcttcacg atcagcccgc tcttcagcgc actggcgcgg ccgtcgcccg catgcggccc
      181 gctcgcgatc ttacgcccgc cttcggaata aatgtcgatc acctcttcca gcgtcgccac
      241 gctgccgtca tgcatgtaag gcgcggtcag cgcgatgttg cgcaggctcg gcgcgcggaa
      301 cttgcccatg tcgtccggat cgccggtgat gtcgaagagc ccgtgattgg gcgcgggata
      361 agcgcccttt ccgtcaatgt cgtagagccc ggtgttatgg aacggcagct ccggctcgcg
      421 cgtcctcgca tgcacgaatt gatcgtcgag gccgacgctg ccatggcagt gatgacattc
      481 cgccttctca ccgaaataaa gatcatgtcc gcgctgctcg gcttcggtga gctgcgcctc
      541 gccctgcaga taatgatcat agcggctgtc gaaggaatag acgccgcgct ggaacgccga
      601 gatcgccgcg atgatcgtcg cgaaggagat gggctcgctc atttcgggaa aggccgcggc
      661 gaaccatcgg cgataatcgg cgtcggcgcg aaagcgcgcg acgatctccg ccttattggc
      721 gtcgctcgcg cccatctcga tcggatcggc gccgaacagc ggattgagca tctgccgctc
      781 caatgtcacc agcgccggat tggcccaggt gagcgttcca tgccagccgg aataggcgat
      841 cgacggcgca ttgcgcggcg tcttcgcgcc cgtcgagccg atggagacgg tgcgtccgtc
      901 ggtaaaggcg cgctcctgca gatggcagga gctgcacgag agcgttccat tgccggagag
      961 gcgcttatcg tagaagaggc gccgcccgag ctggaacttc tcctccgaca tcggattgtc
     1021 gacgggaaca cgcggcggcg ggatgtattt cggtaagtcc caattccagg cgggggccgg
     1081 ctcggccgca gagcgcgcgc cgagaacgag cgcggcgagt acgagaaacg acgcgcgcat
     1141 cattgcttgc cgcccgcgac tttcgacgct gcggcgccga cagagaatat cggcgagacg
     1201 ccgggcctcg atggcttgcc ggcgtcattg gcgccgggcg cgctgtcggc gagattgagg
     1261 ccgagcgcgc ggaacaccgc cgggcagtcg ggatcatcga gcgcgctcat gcagccgacc
     1321 gcgccgccct tgtcgacgct gatgtcgctg ctctcgaaca gcgtcgtcaa atcgagctcg
     1381 acgcgctgcg tcttcggatc gaagcggtcg aagacgacag gaaagcggtt ctcatgcgca
     1441 caggcgacga tctcgccggt cgccggattg cccttgcagc cggtcgagcc gacatggacc
     1501 atccaggtcc gcgacttgga gccgtcgggc ttgatcaccg ccgccggcgg aatgacctcg
     1561 atcgtcacga accggcggcc ggcctgccag ttccacgcca ttccggaaat gtcgagaggc
     1621 ggcggcgcgg cctcgacatt ggaatggttg acgaagacgg gcttgccgtc gacgaggctc
     1681 tccaccgggg cgccgacaga gaaggcgaga ccgacatagg cgccttgcgg cgcggctccg
     1741 acgacggtcg tgttcttggc cggattgccc ggcgtgcaag cggcgttgcc tccgcgcgcg
     1801 tccttgaagt cgagcagcgc gacatcggcg tattgccaat cgttctgcgt cagtgcgatg
     1861 ggtgtgtgct tccctttggc gtcgaccagc tcgaagccat agacgtagag gcgcgcttcg
     1921 tgcagcttgc cggcgaggcg cccgctgccg aggtttgcga gcggcgcgcc gcagcccact
     1981 tccttgccat cggcgacgag cgcgaaacgg actgcgaccg gctgtgtctt cacgcccgcg
     2041 gccagcgccg cgccggcgac aatcagcgct ccggcggcaa ttgtcgcggt ccgcgctcta
     2101 tgcaattccc acatgatcga tcctcctcga attccctccg cccgcgaatg atcggcccct
     2161 tacgcataga cgcgcggaaa gcggaatagc tgaaggaaaa tatattcgct tcccggtcgc
     2221 ggcccttttg cagatccgcg ccggcggtca taggcgccgt cccccgtcgt gagagggccg
     2281 gcgatgcgac tgctagagtc ggccgtaacc tcgaattctc cgattcctct gcggccttgt
     2341 ggcgcacgtt ccgtctcgtc gtcgccctgc ctcggttgat caacactgca tgatcgcctc
     2401 tcaccaagtt cgacgcatga gacgaattac gaggaggtcg aacccgaaaa attttttgct
     2461 gttctcatga gcttcgccgg cgcccgccgc aagatcgatc ggcggctggg cgcgatcgcc
     2521 tctagatcat tccgaccgag gcgcgtggat cgtcgattcc tgtctcaagg cgtctagaag
     2581 gatgtcattg tcctccggcg aaccgaccgc gatgcgcaga cagtcgcgta agcgcgattg
     2641 gggcgaaaag ggtcgcaccc agatttttcg tagctcgatc aaccttcggg cgagcgcggc
     2701 ggcgtcgcca ggcgccgcgc agagcaggaa gttggcgtcg gatcggtagg ggtggaaacc
     2761 gggcaggttc gccagcgcgg tcgaaagacg cgcccgttca cgcttgacgt cctcgacgac
     2821 cgctctgatc agcggcatct cctcgatgaa gatttgcgca atgcgcaagg tgagggagtt
     2881 cagagcatag ggcagagcgg ccttcgcgag ttcccggatg agatttttcg aggcgaccgc
     2941 atagccgaac cggcatcccg cgaggccgat cttcgaaaag gagcgcgtga cgacgacatt
     3001 gtcgcgtgtc gccgcctccg tgacgaagga gcggccggaa tattcggcgt atgcctcgtc
     3061 caggcacaaa atggcgcgag gatcggaagc gagagcgtcg aacgtctctc gctctatgga
     3121 aagcccggtg ggattattcg ggctgcagac atagaaggat ttgctcccgg gctcccgcag
     3181 cagcgcctcc gccactttcg aagacaagga gagatcgtcg tcgagcggaa cgggaacgaa
     3241 ttttcgatcg ttcagattgg cgtaatgagc atacatcgga aaggatggaa tcggcgtgac
     3301 gattctgtgg tccctttcgc cgaaagcgcg gctgatcaaa tcgaggagtt cggtcgagcc
     3361 gaccccgagc aacagattgt cgggctcgac gccgaggtct cgcgccaagg cgaccttgat
     3421 tttttccact tcggcgaaat caggatagca tcgcagatcg accggccaca gctcgtccgc
     3481 gacgcgtttc agaaacctct tcgggagagg aaagcgaaat tcgttgctgt cgagcaagat
     3541 gccgtcgggc cgcggcgcaa cggcgaatat cgggacggcc aggctcgatt tggctcgcat
     3601 cgcgatcggc tcgctcgtga gcccgttcgt ttcacatggg atcgccgtca ttggcctgtc
     3661 tctccctcgg cacgcttcat tcgagcaaag ctttcacgcc ttcgtcggcg ccgaccggtc
     3721 ctttttcacg gaaagcgaga attccgagcc ggccccacat ccaagcggcg caggccgctt
     3781 ctggaaggat cagcgaggaa taagcgacgg ccggggagtc gacgtagagc ccgatggcga
     3841 caagcggcgt cgcgatcagc caaaacgcgg cgccgtcggc ggctgcgacc atggcgaacg
     3901 agccctgcga atggaacaag gctcgggcga tattcgccgc gaagcgaagg ggaagcgaaa
     3961 tcgccagcgc ctggatcagc gtcgaccacc aatgcccgct ctggccatat aagcgaccga
     4021 gcagctcgtc gctctccagc aaggcgaggg cggcggcgac cacgacaggc gcgccctgcg
     4081 cccacactct ccacatcgac gccgagagcc ggccgtcgcg cagcgcagcg tgccggaacg
     4141 ccaggaatcg cgtcagcgcg acgaagggcg tgaacagcat cagcatcaag gtctggccgg
     4201 ccgcgaagga attcatccgc gagacgctgt aattcgcgag ccacggcgcc gcgaacaggg
     4261 agaagcaggc gagtatggcg agctgcacgg atatgagccg ctgcgcctcc caatagatcg
     4321 gacgaaggaa gcgcagcgtc cacgagcatc cgggaagcga aagcctcgcg tcgcccggcg
     4381 gcaacatgcg gcggcaccag atcgacgaca gcgcgccgac gatgaggccg gacaagaagc
     4441 agcccgaaaa tccccatccc aaaacatcca tgaggagcag attggcggcg atcttggccg
     4501 ccgcctcggt caatttccac cgaacgaccg aagggccacg accgagggcg tggaggacga
     4561 atgcgccgat gttgaccaca aaccgaaagg gcgccgccag cgcgtgccag aacacaccct
     4621 cgccgacgag gctcgcgacg tcgccttccc ccgccagcca cctcgccgcc gtgggataaa
     4681 ggagccagcc tagcgcgccg cagagcagtc ccgtcagcag ggccaggccg aggatgcggc
     4741 cgatgaccgg cgcggccccg ccgtttcgtt gcgcctgcgc gaccaccgtc gatgcgaccg
     4801 cgcccatcgc cgtcatcagc acgacttcga cgagcgctag gcgcatcatc atcacataag
     4861 cgccggcggc ggggccgccg aggcggctca tcatcacgat gtccgcttgc tgcgcgagtt
     4921 gagccgaggc cagagccatg agcaatggcc agtagccgcg ccagaagccc gttttgggcc
     4981 gcgtcatcgc gggagcggcc gccagccggg aaaatggtcg atctcgaagc cgggcgtcag
     5041 gaaatagccg aactcgccgt cggggagcgg cagcggcttc tcgaattcga cctgctggac
     5101 ctgctcgagc cggcagtgga tgctgtcgat cttggcgccg acgacggctg cgccggcgag
     5161 cgagcggctt cccagcacga tctgacaggc atcgatgtcg cggtcgatca tcaaccatcg
     5221 cgtcgcggag gcggtcatga cgggcagcag ctgatcctcg tcgagccgct cgcggaactc
     5281 cgattgctgc agccagacat agacccagag gaaaaagctc cagtcgaaag cgaggttgtt
     5341 ctcccgggcc caggccatga agggcaggaa gatggcgccg ccgctcggcc ccgagagctc
     5401 cagcaggcgt gggcatgtgt cgaacaatgt gtgccagtag gcccgaaggc tgatatcgat
     5461 gcgaatgaag ccgcgcgaat ccctgggata gagagactgg cgggcaggat ttgcgagatc
     5521 atcgtagaga tcggcgtcga ttctaaccgg cgcagtgggc aacaggctca tgacgctctt
     5581 cctcgacgca ggggaaaata tcgcgcagtc ttttcaggtc gaccgagatc gactcatagt
     5641 caatgtcgaa atcccgttca taagtgatcg tcgcgccggg cttgtcgaaa gacgtgcgca
     5701 tccggctcag gaaatcgagc gtgtcctccg ccatctcccg gtcgtgcgtg tcggccttga
     5761 cgcgcggctc gatgaaagcc gtgccatatc ctgcaacgtg gaaatggcgc gtggtctcga
     5821 tgattttctt ccacagctcg accggcgcgc cggtgttgtt ctgagcgcag atcgcgttcg
     5881 acgcgtcgaa gagaacgccg accccggtct cccggctcag ccgctcgtag aaggacggcg
     5941 cgtcccatgc gccatccatg atcgacggat aattctcaag atagaggcgc gtgccgagca
     6001 tgtcctgcca ttgctcgacc ttgctccgca cgtggtcgta ttctcgataa tcgatttcgc
     6061 cgagatggaa aaggcttctg ccgttgtgtg tgaagtataa aatatgatca gagacataga
     6121 cgggccgcat cacgtcgatg aatctgcgca gccgcttccc gagcttctcc aattcctccc
     6181 gatctctttc gaggtatttc gaaagcatga tatgaaatgc aacgggacaa tcgaatgaat
     6241 ccgcgatctg ctcgggcggg agatgaacga aattgtcgat caacatttcg acatagtcga
     6301 ttttccgctc tttgatcatc tgctggacca tgtcgagcgt gccggtcagc gtgaagttga
     6361 agccgatctg catcttcgcc tcgtggaata cggccagaat cgccccgaag aggcgagtgc
     6421 cgcccccgag cacatcgagg gcggcggcgc agtcagatca catgcagctg cacggatagc
     6481 acgaaccgca aagcgcagcc gcgcgaccga tgaccggaag gactttcttc tgagcaatct
     6541 tgacagtcat agcttcctcc taagggagtt tccaagttat acctacttga tcgccccact
     6601 ggaacgctca atatagatgc cgcatctgca actccaaaca gcatgcgata tctattaaga
     6661 catatattca aatatattgt caatataaaa tatcaataaa tctagcgtat caaggataaa
     6721 tactgaatac aggcaatatg tataaatatt gaccgatcgg cgcgctggga cgcgcaggaa
     6781 actcggatgt gagttcctcg aatgtcggtc cactaccgcc ttgggcctat gatccgttca
     6841 attctcgatc ccgctttccc ttcgcgtcgc gcgttcacgc ctcctttgcc cgttcctgag
     6901 tggaatgtgc gcctcatatg cggctcggcg gatcgccgac aggcgtttcg attgtcgcga
     6961 aagcgggcgt ccaactctcg gcgtcagcgc cgaagcgagt cgcctccctc tcgcagcccc
     7021 acgcaacatg tccgagccgc cacgccgatc gacctttcgg agcgcgcccc aggacgggga
     7081 catgactcaa aactcgtttc atttttggtc ctcccgctgc gccgacatcg atgatcccgg
     7141 ggggcgctcg ctacaagata cgacgaatga aatcgttgga atccgacaag gcgggagaaa
     7201 aattttgtcg tcggatcgat agaagcgaca cattccttca tgggatgcag ccgactcccg
     7261 tccgcgacgg aaaacgtctc gaacgatcat cggcgagcgt gaggatgccc gtccggcggc
     7321 tctgggcaaa cgttcgagcc gccggcgaag aagacccgaa cgtcctagaa ttccacgcga
     7381 atggagccga gaaccgtgcg cggcgcgccc actgtgatcg tggtgcgatt caacgaagcc
     7441 ggatagtaga tggcgtcggt gagattcttg acgttcagct gcgccgtgac ggctgcgcct
     7501 tcgacctcga aacgatagga ggccatcgca ttgacgagcg tgtagtccgg caattggaag
     7561 tcattggcgg tgtcgccctg catcgatccg acgatcgaga cgccgccgcc gaggctcaac
     7621 ccctcgaaag ccccgtgggc gtcatatttg agccagagat tcccggcgtt cagcggcgcc
     7681 gagggcagcc tgcggccgat attcgccttg ttattgtcct tcgtgacgac ggcgtagtcg
     7741 tggctgaaat tgccgatgac gctccaattg tcgtccaaac gcccggtgag gtcgaattcg
     7801 acgccttcgc tctccgcttc gccaatcagc gtggagaacc gcggattgag cgggtcgggc
     7861 gtcggaatat ttgtcttcgt gatgtcgtaa taggcgaagg tcgccgtcag gcgcttgtcg
     7921 aagaactccg ctttcacgcc gccttcccat tgccgggccc tctgcggcgc cagaggaata
     7981 ttgccgccgg tgacgccatt gttggcgccg aaggattgag agtagtttcc atagaatgac
     8041 agccagggaa acggctggat cgaaagtccg atgcgcggac tgaacgcttc attgtaaatc
     8101 gtgacggcgg cgttcttggc ggagacatag gagacggagc tgaacgaatt gacggcatcc
     8161 gcccagtcat atctgccgcc gagaagcaga tgcgccctgt cgtcgaaggc cgagatcatg
     8221 tcctggagat agaggccttt ccaattctct cgcgcgtaag tgaaggcgtt gggcgtaggc
     8281 ttgtagggaa cgcccgaacc atagaccggc gcatagatgt tgatcgactt cacatagggc
     8341 gatacgccga gataaccatt atattgatcc tgattctcgg tgaaaaagtc gccccccacc
     8401 agcaagtcgt gccgcaacgg accggtttcg aactttccct tgaggtcgag attggtggaa
     8461 agagatccga cgtaagtcgg tgtcatgaag aggcggcgcg tcgcgtcgcc cgtcgcctcg
     8521 ttgatcgaac cgaaataagt cgtcgtgaca ccgtgatatc catattcata cagcagccga
     8581 ttggtcaggc tccaatcctt gtcgaaggcg aaggtccaat cgtaaccgat cagttcgcgg
     8641 gtatgccggg tggggttgtt ggcggtgacc gccggatctt gcagatatcg gctgatggga
     8701 accgaagccg gacgcgttcc gattgcagga atcgtctgat aaacgtcgac gagaatcgag
     8761 tcctggaatt ccgcgtcgac attcaggcgg aattgctcgt cgggatgaaa ggtgatcgtc
     8821 ggcgcgataa aaacgttctg actatttgcg taatcgatgt acgaatcggc gtgcatgaaa
     8881 ttgccggaga tacgatagag ccaggttcga tcgggagtca ggggaccggt ggcgtccacg
     8941 ctcgttcgcg tcattccgaa cgagccggct tgttcctgaa aggaataata tggcgtctcc
     9001 aatgggcgct tcacgaccag atcgatgata ccgcccggct cgacacggcc gtagagcatg
     9061 ccggccgggc ctttgagaat ctcgacggat tggagattgg aggtgtcgag ggtggagacg
     9121 aggtgccgtc tcaaattgtt tcggtagacg ccgtaattgg tggaaaagcc acgaatgttg
     9181 aaactgtcgt atgtcgaggc cgaggggttc tgagacacgc tgctggcgtt ggtggtgagc
     9241 gcctcttgta tgctgatcgc ctgctgatca tccatggtct gccgcgtgac gacctgcacc
     9301 gccaccggcg tctgcaggat cggcgtatcc gttttcaacg cggaagtggc ggacggggcg
     9361 ctatatcccg tcgctctgtc gcccggtcct cgtaccccgg cggcgcccct ctcgcttcga
     9421 gcctcgcgtc cgacatcgat ggtcggcaac gccgtcgcgc cgctcgcgtc agtgcggacg
     9481 cccgtgtcgt tctgcgccag cacgatcgat acggaccgtc cattgtccgc gaaacgatag
     9541 gcgagtccgg agccgcgcag cagccggtcg aggccgtcct tcgtcgaaaa agcgccatcg
     9601 agtccggagg tcgtcaggcg ctcggtcacg cgcgcgtcat atgcgatgtg cagcccgctg
     9661 acataagcga atgtgttgag cgccgtcgcc atcgaaccgg gcggaatctc atatttctgg
     9721 atccacccca agcgctctcg cgccggaatc gacgcctgtg cgggcgagtc ggcggcgccg
     9781 gcgccgatcg tcaaaacgcc cat
//
