LOCUS       BGC0002006              3346 bp    DNA     linear   CON 22-MAR-2023
DEFINITION  Streptomyces albus strain ZD11 chromosome, complete genome.
ACCESSION   BGC0002006
VERSION     BGC0002006
KEYWORDS    .
SOURCE      Streptomyces albus
  ORGANISM  Streptomyces albus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP033071.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Institute of Pharmaceutical
            Biotechnology, Professor Wenjun Guan.
            COMPLETENESS: full length.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:42:05
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3346
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3346
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[209:2754]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      210..2754
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     cand_cluster    1..3346
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..3346
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002006"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..3346
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..138
                     /gene="albA"
                     /locus_tag="DUI70_RS10785"
     CDS             1..138
                     /codon_start=1
                     /gene="albA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_103055247.1"
                     /locus_tag="DUI70_RS10785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide albusnodin"
                     /protein_id="WP_103055247.1"
                     /transl_table=11
                     /translation="MDSLLSTETVISDDELLPIEVGGTAELTEGQGGGQSEDKRRAYNC
                     "
     gene            210..2030
                     /locus_tag="DUI70_RS10790"
                     /old_locus_tag="DUI70_2232"
     CDS             210..2030
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 108.8; E-value: 4.8e-33)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033561.1"
                     /locus_tag="DUI70_RS10790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DUI70_2232"
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_040248810.1"
                     /sec_met_domain="Asn_synthase (E-value: 5e-34, bitscore:
                     106.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFGGFSTTREVRQRPGNAEFIATDSPIWRLGRSPARCVAADHGQ
                     RRLVVLGECGATDGELSRLATAGLPTDITWRWPGVYVVVEEQPERTVLHTDPAAALPVY
                     ATPWQGGWAWSTSARILARLTEAPIDGQRLACSVLAPSVPALSGTRTFFAGIEQLALGS
                     RIELPVDGSRLRVTVRWRPDPVPGEPYHRLRTALTEAVALRVNRAPDLSCDLSGGLDST
                     SLAVLAAVCLPESHHLNAITIHPEGDESGADLRYARLAAAHHGRIRHHLLPLAAEHLPY
                     TEITAVPPTTEPAPSTLTRARLAWQLDWMRQHLGSRTHMTGDGGDSVLFQPPAHLADLL
                     RHRQWRRTLSESLGWARLRHTSVLPLLRGAATLARTSRRSGLQDLARALAGAGQQGDGR
                     GNVSWFAPLPLPGWATPTARRLLLDAADEAISTADPLPGLDTSLRVLIDEIREVARTAA
                     ADAELADAHGTTLHNPFLDPRTIDAVLRTPIAHRPAVHSYKPALGHAMQDLLPGAVARR
                     STKGSFNADHYAGMRANLPALTALADGHLADLGLLEPTRFRSHLRQAAAGIPMPLAAIE
                     QALSAEAWCHAHHATPSPAWTTQPPEHPHA"
     gene            2023..2754
                     /locus_tag="DUI70_RS10795"
                     /old_locus_tag="DUI70_2234"
     CDS             2023..2754
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520044.1"
                     /locus_tag="DUI70_RS10795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DUI70_2234"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_040248813.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 3.1e-09,
                     bitscore: 25.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 1.7e-24, bitscore: 74.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELPRFATAPRHVRALDFGHVLVLIDYRSNHVQCLLPAAAAHWT
                     ATARTGRLDTMPAALATQLLTSALLVPRPTATPWTAPVAAPPAPPSWGGSEHPAGTSRP
                     RARHRHSTTAAAALACVLAIKAAGPTRYAMQRLTTVVKAAASTCRRPATPAQATAAALA
                     VRQACWYSPARTACLEESAATVILLATRRLSSTWCHGVAPDPIRLHAWVETEDGTPVAE
                     PASTLAYTPALTIGGHHQHQP"
     gene            2768..3346
                     /locus_tag="DUI70_RS10800"
                     /old_locus_tag="DUI70_2235"
     CDS             2768..3346
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 80.7;
                     E-value: 2e-24)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.2"
                     /locus_tag="DUI70_RS10800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DUI70_2235"
                     /product="GNAT family protein"
                     /protein_id="WP_257786959.1"
                     /transl_table=11
                     /translation="MSTDTCGLGPYRADLVDTYWQWEQDPTLLVGYGRQSPQSLEARTE
                     GMAHQLRGDNIRFTIYDLCSSTPTPAGVATLLPDHSVRTAEYVIMLAPEARGRGLGTTA
                     TQLTLDYAFHITNLRMVWLKVLAPNTAGIRAYEKAGFRTVGALREAGYWLGKVCDEVLM
                     DALAKDFTGPSAVHAALTGASGRQLRRAP"
ORIGIN
        1 atggacagcc tgctcagcac cgagaccgtc atctccgacg acgaactcct gccgatcgag
       61 gttggcggca ccgccgaact gaccgagggc cagggcggag gccagagcga ggacaagcga
      121 cgcgcctaca actgctgacc cctccgcggt ggtggtgctg ccctgcggcc gcaccaccac
      181 cgcaccgtgc gacccgcctg gaggcaatcg tgatcttcgg aggattcagc accacacgag
      241 aggttcgcca gcgtcccggg aacgccgagt tcatcgccac cgattcgccg atctggcggc
      301 tcggacgctc cccggcacgc tgtgtggcag cggaccacgg gcaacggcgc cttgtggtcc
      361 tgggcgagtg cggcgccacc gacggcgagt tgagccgcct ggccaccgcc ggactgccga
      421 ccgacatcac ctggcgctgg cccggcgtct acgtggtcgt cgaagagcaa ccggaacgca
      481 cggtgctgca caccgatcca gccgccgcgc tccctgtcta tgcgacgccg tggcagggtg
      541 gctgggcctg gtccacctcc gcccggatac tcgcccgcct caccgaggca cccatcgacg
      601 ggcaacggct cgcctgctcc gtacttgctc cgtcggtccc ggccctgtcc ggtacgcgaa
      661 ccttcttcgc cgggatcgag cagctggccc tgggcagccg gatcgaactc cccgttgacg
      721 gcagccgtct gcgggtcacc gtgcgatggc ggcccgatcc ggtcccgggt gagccgtacc
      781 accgtctgcg cacggccctg accgaggcgg tggccctgcg ggtgaacagg gccccggact
      841 tgtcgtgcga cctgtcggga ggactggact ccaccagcct tgccgtcctc gccgcggtct
      901 gtctgcccga gtcccaccac ctgaacgcga tcacgatcca ccccgagggc gacgagagcg
      961 gcgcggacct gcggtacgcc cgcctggccg ccgcgcacca cggtcggatc cgtcaccatc
     1021 tcctgccgct ggccgccgag cacctgccct acaccgagat caccgccgtg cccccgacca
     1081 ccgagcccgc cccctcgacg ctcacccgag cccgcttggc ctggcaactc gattggatgc
     1141 gccagcacct gggcagccgg acccatatga ccggggacgg cggagacagc gtcctgttcc
     1201 agccgcccgc gcacctcgcc gacctcctgc gtcaccgcca gtggcgacgg acgctgagcg
     1261 agagcctcgg ctgggcacgg cttcgccaca cctccgtcct cccgctcctg cgcggcgccg
     1321 cgaccctggc ccgcaccagc cgacgaagcg ggctccagga cctggcccgc gcccttgccg
     1381 gagcaggaca acaaggcgac ggccgcggca acgtctcctg gttcgcgccc ctgccgctgc
     1441 ccggctgggc cacacccacg gcccgacggc tgctgctcga cgcggccgac gaggcaatca
     1501 gtaccgcaga tccgctgccc ggcctggaca cgtcgctgcg cgtcctcatc gacgagatcc
     1561 gcgaagtcgc ccgcaccgct gccgccgacg ccgaactcgc cgacgcccac ggcaccactc
     1621 tccacaaccc cttcctcgac ccacgcacca tcgacgccgt cctgcgcacc cccatcgcac
     1681 accgcccggc agtccactcc tacaagcccg ccctcggcca cgcgatgcag gacctgctcc
     1741 ccggcgccgt cgcccgccgc agcaccaagg gcagcttcaa cgccgaccac tacgccggaa
     1801 tgcgcgccaa ccttcccgcc ctcacggctc tggccgacgg ccacctggcc gacctcggac
     1861 tcctcgaacc gacccgcttc cgcagccacc ttcgccaggc cgccgccggc atcccgatgc
     1921 ccctggccgc gatcgaacag gctctgagtg ccgaggcatg gtgccacgcg caccacgcca
     1981 cgccgagccc ggcttggact acacaaccgc cggagcaccc tcatgcctga actgccacga
     2041 ttcgccaccg ccccgcgcca cgtccgagct ctggacttcg ggcatgtcct ggtcctgatc
     2101 gactaccgct ccaaccacgt ccagtgcctc ctcccggcag ccgcggccca ctggacggca
     2161 acggctcgca ccggccggct ggacaccatg cccgccgccc tcgccaccca gctcctgacc
     2221 tccgcactcc tcgtcccgag gcccaccgca acaccctgga ccgcccccgt cgctgccccg
     2281 cccgcaccac cgagctgggg aggatccgag caccccgccg ggaccagccg accccgagcg
     2341 aggcaccgcc acagcaccac cgcagccgcc gcactggcct gcgtcctcgc catcaaggcc
     2401 gcaggaccca cgaggtacgc gatgcagcgt ctcaccaccg tggtgaaggc cgccgcgtca
     2461 acatgccgcc gaccggccac cccggctcag gcgacggccg ccgccctcgc cgtacgccag
     2521 gcgtgctggt actccccggc ccggaccgcc tgcctggaag aatccgccgc caccgtcatc
     2581 ctcctggcca cgcggcggct gtccagcacc tggtgccacg gcgtcgcccc ggaccccata
     2641 cgactgcacg cctgggtgga gactgaggac ggcacccccg tcgccgagcc cgcctcgacg
     2701 ctcgcctaca cgcccgcact caccatcgga ggccatcatc agcaccagcc ctgagcaaac
     2761 cctgtggatc agcaccgaca cctgcggcct cggcccctac cgcgccgacc tggtcgacac
     2821 gtactggcag tgggagcagg accccaccct cctcgtcggc tacggccgcc agagccccca
     2881 gtccctcgaa gcccgcaccg agggcatggc ccaccaactt cgcggcgaca acatccgctt
     2941 caccatctac gacctgtgca gcagcacccc gacacccgcc ggcgtcgcca cgctcctgcc
     3001 ggaccactcc gtacgcaccg ccgagtacgt gatcatgctc gcgccggaag cccgcggtcg
     3061 cggcctggga accacagcga cccagctcac cctcgactac gccttccaca tcaccaacct
     3121 gcggatggtc tggctcaagg tcctcgcgcc caacaccgcg ggcatccgcg cctacgagaa
     3181 ggccggcttc cgcacagtcg gtgccttgcg ggaagccggg tactggctcg gcaaggtctg
     3241 cgacgaggtc ctcatggacg ccctcgccaa ggacttcacc gggccgtccg ccgtgcatgc
     3301 ggcattgacc ggcgccagtg gccgtcagct ccgccgagca ccgtag
//
