BGC0002008 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002008 (Xenorhabdus doucetiae)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	arylpolyene	1	43,657	High	aryl polyenes	other:other

BGC0002008 - Region 1 - arylpolyene

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Location: 1 - 43,657 nt. (total: 43,657 nt) Show pHMM detection rules used

Region on contig edge.

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 43,658
Label		BGC0002008

Tailoring functions

Oxidoreductases: dehydrogenase

XDD1_RS16060: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: acyltransferase methyltransferase

XDD1_RS15985: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

XDD1_RS15995: acyltransferase

smcogs: SMCOG1141: acyltransferase

Ligases: ligase synthase

XDD1_RS16015: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

XDD1_RS16025: polyprenol-monophosphomannose synthase ppm1

smcogs: SMCOG1123: polyprenol-monophosphomannose synthase ppm1

XDD1_RS16050: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

XDD1_RS16065: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.3	1.00	other (other)	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.5	0.80	other (other)	APE Ec	Escherichia coli CFT073
BGC0000837.4	0.65	other (other)	APE Vf	Aliivibrio fischeri ES114
BGC0002276.2	0.60	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0001160.5	0.60	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0001164.3	0.60	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001258.3	0.59	PKS	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001197.5	0.49	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0001723.5	0.49	PKS	oviedomycin	Streptomyces antibioticus
BGC0000234.5	0.48	PKS	jadomycin	Streptomyces venezuelae ATCC 10712

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.3	1.00	other (other)	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.5	0.80	other (other)	APE Ec	Escherichia coli CFT073
BGC0000837.4	0.65	other (other)	APE Vf	Aliivibrio fischeri ES114
BGC0002276.2	0.60	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0001160.5	0.60	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0001164.3	0.60	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001258.3	0.59	PKS	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001197.5	0.49	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0001723.5	0.49	PKS	oviedomycin	Streptomyces antibioticus
BGC0000234.5	0.48	PKS	jadomycin	Streptomyces venezuelae ATCC 10712

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS substrates

NRPS/PKS substrate predictions

XDD1_RS16015: X

AMP-binding (36..293): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: --FIVAIIMK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

Link to PARAS substrate predictor