BGC0002009: kanglemycin A biosynthetic gene cluster from Amycolatopsis vancoresmycina
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 420,871 - 518,113 nt. (total: 97,243 nt).
This entry is originally from NCBI GenBank NZ_JNYY01000005.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002009
Short description kanglemycin A biosynthetic gene cluster from Amycolatopsis vancoresmycina
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: NZ_JNYY01000005.1
Compounds
  • kanglemycin A
  • kanglemycin V1
  • kanglemycin V2
Species Amycolatopsis vancoresmycina [taxonomy]
References
Chemical products information
kanglemycin A
(no structure information available)
kanglemycin V1
(no structure information available)
kanglemycin V2
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • OO60_RS14025
  • WP_003071771.1
 420872 - 422086 (-) LuxR family transcriptional regulator
copy AA seq
copy Nt seq
  • OO60_RS14030
  • WP_003071773.1
 422651 - 423100 (-) 3-dehydroquinate dehydratase
copy AA seq
copy Nt seq
  • OO60_RS14035
  • WP_003071775.1
 423344 - 424603 (+) cytochrome P450
copy AA seq
copy Nt seq
  • OO60_RS14040
  • WP_003071776.1
 424672 - 425583 (-) transketolase
copy AA seq
copy Nt seq
  • OO60_RS14045
  • WP_003071778.1
 425580 - 426275 (-) thiamine pyrophosphate-dependent enzyme
copy AA seq
copy Nt seq
  • OO60_RS14050
  • WP_003071780.1
 426474 - 427742 (+) cytochrome P450
copy AA seq
copy Nt seq
  • OO60_RS14055
  • WP_003071782.1
 427786 - 428523 (+) alpha/beta fold hydrolase
copy AA seq
copy Nt seq
  • OO60_RS14060
  • WP_033261516.1
 428541 - 429746 (+) acyltransferase
copy AA seq
copy Nt seq
  • OO60_RS14065
  • WP_003071786.1
 429743 - 431197 (+) bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase
copy AA seq
copy Nt seq
  • OO60_RS14070
  • WP_003071788.1
 431194 - 432228 (-) CoA transferase
copy AA seq
copy Nt seq
  • OO60_RS14075
  • WP_003071791.1
 432225 - 432620 (-) cobalamin B12-binding domain-containing protein
copy AA seq
copy Nt seq
  • OO60_RS14080
  • WP_033261449.1
 432620 - 434197 (-) methylmalonyl-CoA mutase family protein
copy AA seq
copy Nt seq
  • OO60_RS14085
  • WP_003071800.1
 434267 - 436051 (-) ABC transporter ATP-binding protein/permease
copy AA seq
copy Nt seq
  • OO60_RS14090
  • WP_051767685.1
 436051 - 437820 (-) ABC transporter ATP-binding protein/permease
copy AA seq
copy Nt seq
  • OO60_RS14095
  • WP_244885523.1
 438046 - 440025 (+) multicopper oxidase domain-containing protein
copy AA seq
copy Nt seq
  • OO60_RS14100
  • WP_004562633.1
 440095 - 441690 (-) acyl-CoA carboxylase subunit beta
copy AA seq
copy Nt seq
  • OO60_RS14105
  • WP_004562634.1
 441797 - 443062 (-) cytochrome P450
copy AA seq
copy Nt seq
  • OO60_RS14110
  • WP_004562636.1
 443253 - 444419 (-) cytochrome P450
copy AA seq
copy Nt seq
  • OO60_RS14115
  • WP_004562638.1
 444652 - 446076 (+) NDP-hexose 2,3-dehydratase family protein
copy AA seq
copy Nt seq
  • OO60_RS14120
  • WP_004562640.1
 446120 - 447271 (+) glycosyltransferase
copy AA seq
copy Nt seq
  • OO60_RS14125
  • WP_004562641.1
 447297 - 448277 (+) 5'/3'-nucleotidase SurE
copy AA seq
copy Nt seq
  • OO60_RS14130
  • WP_004562642.1
 448338 - 449105 (-) class I SAM-dependent methyltransferase
copy AA seq
copy Nt seq
  • OO60_RS14135
  • WP_004562643.1
 449124 - 450185 (-) aldo/keto reductase
copy AA seq
copy Nt seq
  • OO60_RS14140
  • WP_004562644.1
 450215 - 450976 (-) NAD-dependent epimerase/dehydratase family protein
copy AA seq
copy Nt seq
  • OO60_RS14145
  • WP_156081305.1
 450976 - 454188 (-) S41 family peptidase
copy AA seq
copy Nt seq
  • OO60_RS14150
  • WP_003062297.1
 454346 - 455542 (+) cytochrome P450
copy AA seq
copy Nt seq
  • OO60_RS14155
  • WP_003062299.1
 455532 - 456416 (-) ROK family protein
copy AA seq
copy Nt seq
  • OO60_RS14160
  • WP_003062302.1
 456422 - 457120 (-) HAD-IA family hydrolase
copy AA seq
copy Nt seq
  • OO60_RS14165
  • WP_033261451.1
 457133 - 458206 (-) Gfo/Idh/MocA family oxidoreductase
copy AA seq
copy Nt seq
  • OO60_RS14170
  • WP_003062304.1
  • rifK
 458280 - 459440 (-) 3-amino-5-hydroxybenzoate synthase
copy AA seq
copy Nt seq
  • OO60_RS46435
  • WP_155848838.1
 459483 - 459689 (-) hypothetical protein
copy AA seq
copy Nt seq
  • OO60_RS14175
  • WP_033261524.1
 459774 - 460562 (-) shikimate dehydrogenase
copy AA seq
copy Nt seq
  • OO60_RS14180
  • WP_004559804.1
 460559 - 461815 (-) 3-deoxy-7-phosphoheptulonate synthase
copy AA seq
copy Nt seq
  • OO60_RS14185
  • WP_004559805.1
 461812 - 462867 (-) 3-dehydroquinate synthase
copy AA seq
copy Nt seq
  • OO60_RS14190
  • WP_004559806.1
 462864 - 463052 (-) hypothetical protein
copy AA seq
copy Nt seq
  • OO60_RS14195
  • WP_004559807.1
 463071 - 463847 (-) arylamine N-acetyltransferase
copy AA seq
copy Nt seq
  • OO60_RS14200
  • WP_033261452.1
 463865 - 474211 (-) type I polyketide synthase
copy AA seq
copy Nt seq
  • OO60_RS14205
  • WP_240490790.1
 474264 - 479618 (-) type I polyketide synthase
copy AA seq
copy Nt seq
  • OO60_RS47765
 479689 - >479694 (-) hypothetical protein
copy AA seq
copy Nt seq
  • OO60_RS14210
  • WP_033261453.1
 479767 - 485190 (-) type I polyketide synthase
copy AA seq
copy Nt seq
  • OO60_RS14215
  • WP_033261454.1
 485200 - 500367 (-) type I polyketide synthase
copy AA seq
copy Nt seq
  • OO60_RS14220
  • WP_003060229.1
 500401 - 514653 (-) type I polyketide synthase
copy AA seq
copy Nt seq
  • OO60_RS14225
  • WP_003060232.1
 514695 - 515885 (-) cytochrome P450
copy AA seq
copy Nt seq
  • OO60_RS14230
  • WP_033261526.1
 515919 - 516134 (-) DUF5988 family protein
copy AA seq
copy Nt seq
  • OO60_RS14235
  • WP_003060236.1
 516321 - 517088 (-) Gfo/Idh/MocA family oxidoreductase
copy AA seq
copy Nt seq
  • OO60_RS14240
  • WP_240490590.1
 517085 - 518077 (-) Gfo/Idh/MocA family oxidoreductase
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: SJG3CBEHSM6A3I74YXLH6GLA, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added chemical activity and supporting publication
  • Refined reference coordinates
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.