BGC0002015: aborycin biosynthetic gene cluster from Streptomyces sp. ZS0098
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Location: 18,549 - 30,566 nt. (total: 12,018 nt).
This entry is originally from NCBI GenBank NZ_MKCP01000039.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002015
Short description aborycin biosynthetic gene cluster from Streptomyces sp. ZS0098
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
NZ_MKCP01000039.1
18549 - 30566
via
Compounds
  • aborycin
Species Streptomyces sp. ZS0098 [taxonomy]
References
Chemical products information
aborycin Evidence:
Copy SMILES
C97H131N23O26S4
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BIU87_RS24165
  • WP_147474396.1
 18549 - 19250 (-) response regulator transcription factor
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    • BIU87_RS24170
    • WP_122215938.1
    		 19732 - 20871 (+) sensor histidine kinase
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      • BIU87_RS24175
      • WP_183153327.1
      		 20982 - 21884 (+) ATP-binding cassette domain-containing protein
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        • BIU87_RS24180
        • WP_102640375.1
        		 21877 - 22629 (+) ABC transporter permease
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          • BIU87_RS24185
          • WP_106963308.1
          		 22746 - 22874 (+) aborycin family tricyclic lasso peptide
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            • BIU87_RS24190
            • WP_122215940.1
            		 22936 - 24747 (+) lasso peptide isopeptide bond-forming cyclase
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              • BIU87_RS24195
              • WP_037640857.1
              		 24744 - 25007 (+) lasso peptide biosynthesis PqqD family chaperone
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                • BIU87_RS24200
                • WP_122215941.1
                		 25004 - 25429 (+) lasso peptide biosynthesis B2 protein
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                  • BIU87_RS24205
                  • WP_122215942.1
                  		 25426 - 26391 (+) ATP-binding cassette domain-containing protein
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                    • BIU87_RS24210
                    • WP_122215943.1
                    		 26388 - 27257 (+) ABC transporter permease
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                      • BIU87_RS24215
                      • WP_122215944.1
                      		 27271 - 27744 (+) DoxX family membrane protein
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                        • BIU87_RS24220
                        • WP_122215945.1
                        		 27747 - 28472 (+) thioredoxin domain-containing protein
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                          • BIU87_RS24225
                          • WP_122215946.1
                          • mslH
                          		 28469 - 29815 (+) lasso peptide C-terminal Trp epimerase
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                            • BIU87_RS24230
                            • WP_122215947.1
                            		 29889 - 30566 (+) response regulator transcription factor
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                              Biosynthesis information
                              Annotation changelog

                              Entry version: 3

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-10-07
                              Update chemical activity to schema version 2.11
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 2

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-09-15
                              Cleaned up synonym list
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              2022-09-15
                              Fetch compound properties from PubChem
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              2022-09-15
                              Updated bioactivity data
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 1

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2019-10-16
                              Submitted
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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