LOCUS       BGC0002016             28409 bp    DNA     linear   BCT 22-FEB-2018
DEFINITION  Streptomyces sp. QL37 scaffold1_size8772908, whole genome shotgun
            sequence.
ACCESSION   BGC0002016
VERSION     BGC0002016
KEYWORDS    .
SOURCE      Streptomyces sp. QL37
  ORGANISM  Streptomyces sp. QL37
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     Bacteria and source DNA available from Gilles P. van Wezel,
            Sylviusweg 72 2333 BE Leiden, Netherlands.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 06:00:34
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 28409
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..28409
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[9629:12127]"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 689.2; E-value:
                     3.4e-210)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 384.421"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 426.458"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
                     /tool="antismash"
     proto_core      9630..12127
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="1"
                     /t2pks_malonyl_elongations="8|9 (Score: 689.2; E-value:
                     3.4e-210)"
                     /t2pks_molecular_weights="acetyl-CoA_8 (Da): 384.421"
                     /t2pks_molecular_weights="acetyl-CoA_9 (Da): 426.458"
                     /t2pks_product_classes="angucycline"
                     /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)"
     cand_cluster    1..28409
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..28409
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002016"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..28409
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T2PKS"
                     /region_number="1"
                     /rules="(t2ks and t2clf)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..597)
                     /locus_tag="C5F59_12855"
     CDS             complement(1..597)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127613.1"
                     /locus_tag="C5F59_12855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FMN reductase"
                     /protein_id="PPQ57481.1"
                     /transl_table=11
                     /translation="MDNDTYRLVILVGSVREGRFGPVVASWVAEQAVNHGGFDVKTVDL
                     ADIDIPLELPAASPKYAGDDYPRPAGMAALTSALEGADAFVVVSPEYNHSYPASLKAAI
                     DWHFTQWAAKPVAFVSYGGAAGGRHAVLHLENVLTELHAVTIRDGLAFPDYYTAWEDGR
                     PLGPEVPGYAKTLFEQLAWWAGALRTAREANPYPA"
     gene            710..1549
                     /locus_tag="C5F59_12860"
     CDS             710..1549
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119337.1"
                     /locus_tag="C5F59_12860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /protein_id="PPQ57482.1"
                     /transl_table=11
                     /translation="MGTPLGDFIRAKRDSIQPQSLGLPDHGRRRAPGLRRSDLAGRAGI
                     SVEYLTRLEQGRDRNPSVAVVNAVADALGLDTAERSHLRYLVKITGGECTAHTRPSPAP
                     REVRPPVLETLRLLEPGIAVVTNRLGDVLARTGAYEAVTSGTGLLDSDSPNLTRYVFTD
                     PRARMFFADWDDVADEQAFDLWFAPSVENTEWFTAELAPVAGPDFTGRLNGHVVPRRGV
                     LRLNHPSGEELRLLRETLDLSSDAQQLVVLLPADEGTAQAVARLRSLPPHGRLRAIS"
     gene            complement(1585..2253)
                     /locus_tag="C5F59_12865"
     CDS             complement(1585..2253)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 77.5; E-value:
                     1.4e-23)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003765346.1"
                     /locus_tag="C5F59_12865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="PPQ57483.1"
                     /transl_table=11
                     /translation="MVFAANHALVRDSVAGILHAQEDILLLGATLHRVEALQLVADQSP
                     HVIVLEPSEILNDSVSTIRSLRRAHPRSALLVIPPYRAGDRTALLEAGAHVVLARDAGA
                     GALLAAARYLATPAKSDAARESPIALSPRELQVVRCAAAAMTNQQIASRLGITLGTVKR
                     HLHSAFRKLGAVSRLDAVRKALTAGLLSAPVPAPAPVALKHGARAEGTPPGHRDTASAA
                     "
     gene            complement(2804..3520)
                     /locus_tag="C5F59_12870"
     CDS             complement(2804..3520)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 113.5; E-value: 2.8e-34)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453018.1"
                     /locus_tag="C5F59_12870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="PPQ57484.1"
                     /transl_table=11
                     /translation="MTEARTSEAPRRNASRGRIDKRRAILDAAFRVFAREGYGQSCVQE
                     IAAEAGVAKPTIYNHMHDKESLFREAMETVAVRTADRNLAALDPLREPSGDVGNALTET
                     GRLLLRCHCADESWALRRLLYAEAARFPDLLESVQRQGGRRLVETLADRLARLALAGRL
                     RTQDPDVAAEQFLALLTGPAEARSVLGTRPLPEGELDDVVEAAVRTFLHAYSPAASTPA
                     VRFSDADGAGAAGGRG"
     gene            3667..5145
                     /locus_tag="C5F59_12875"
     CDS             3667..5145
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 331.5; E-value:
                     1.1e-100)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103033.1"
                     /locus_tag="C5F59_12875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="PPQ57485.1"
                     /transl_table=11
                     /translation="MSQAQDDRLDPRLLRLIGVVLLGGIMGILDSTMVAVAADTLSEEF
                     NTSLTAISWASTAYLLTLTVTIPVTSWAIGRFGVKKLWLFGLVLFLAGSLASALAWNVE
                     SLIVFRVLQGLGSGVLDPLVLVILARAAGPSRAGRVMGMMGVVLSLGPVLGPVLGGVVL
                     EALDWRWMFFINLPIGVVAFFLATRVIPADPKAAQQSGTGLDVLGFALMAPGFAAMVLG
                     LTQAGEHATFGTPTVLVPLGLGLVLLVAYVLHALRARRTPPLIDVRLFSSRSFAASVTV
                     QGLVGLATYAGLFALPLYYQLLHGHDARAAGLLVAPLGLGSALAMPLAGRLSDRMGARN
                     LAAGGAVIAGLGGVALTQIGADTTELLSALGAFAIGLGLGAVGAPTMGALYRTLPPEKV
                     PQGSSVLYNLNQLGGALGVAGVALILATMNADKGSTADAVSGFHGVYWFVTAVSVVILL
                     ATPLLPGRPEAPAAPAGETPTGEAPAKETAGRAG"
     misc_feature    3706..3708
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5338..5763
                     /locus_tag="C5F59_12880"
     CDS             5338..5763
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /locus_tag="C5F59_12880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /product="hypothetical protein"
                     /protein_id="PPQ57486.1"
                     /transl_table=11
                     /translation="MAPSTAAAAGSRTRTRTADRAASLRRRTATLLTTGRSTSVWSFHA
                     HSSETANAPRTTAAATGVDRLLSAPSRRCPYTRTRPCTMEKPKETSPSQIGRRPADGAP
                     RSWAFRSAWVTAATSRASGITGRATRLYRYGAWQASQ"
     gene            6602..7588
                     /locus_tag="C5F59_12885"
     CDS             6602..7588
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 241.6; E-value:
                     2.2e-73)"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     C2O|C2N (Score: 303.3; E-value: 4.5e-93)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453021.1"
                     /locus_tag="C5F59_12885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase"
                     /protein_id="PPQ62299.1"
                     /transl_table=11
                     /translation="MGILSGYWHTKILLTATEADLFTVLSGGSATAEELADRLRFRLPG
                     ASDFLLALAGIGLLEAAEDGTFRNSAAAEAFLVSGRPGYVGGYLKFCDRELNPAWDGLG
                     ESLRTGLPRNAAAREGNPYHTLYQDTEATDSFLESMDMLNTPILERVGALDWSPYESFV
                     DVGGARGNLAHHLTGAHPHLKGAVFDLPPLAEAFGTHMKALGGGDGIAFHGGDFFSDPL
                     PGADVIVLGHVLHNWGPKDRAALLRTAYDAVRPGGAVLVYDPMVSNSRPPLYATLASLS
                     MLVWSAGGGEYSVAECHALMKEAGFRPETVGPEDTVDDVLVLGHKDR"
     gene            7654..9123
                     /locus_tag="C5F59_12890"
     CDS             7654..9123
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 536.7; E-value:
                     1.1e-162)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 565.6; E-value: 2.1e-172)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453024.1"
                     /locus_tag="C5F59_12890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="monooxygenase"
                     /protein_id="PPQ57487.1"
                     /transl_table=11
                     /translation="MDASVVVVGAGPAGLMLAGELRLAGIDVVVLEKLARSTGESRGIG
                     FTPRTMEVFDQRGLLSRFGDIEKSGQGHFGGIPLDFEVLGGGELAARSVPQSVTESVLE
                     AWARELGADIRRGHEFAGLTDHGDRVDVRVRDSGHEHTLSAAYLVGCDGGRSGVRKAGG
                     FDFPGTAATTELFLADVRGVDLEPRMVADRVTDGMVMVGRLGDGVHRIIVSERGAPPQR
                     RTGPPAFAEVADVWKRLTGIDISHAEPVWVSAFGDASRQVTEYRRGRVLLSGDSAHIHL
                     PAGGQGMNTSVQDSVNLGWKLAAVLRSTAPPALLDTYHSERHEVGRRLLANTRAQSLLL
                     LGSEDVQPLRDMLAELALHEEVSRTLAAKAAGLDIRYDVGKGVNPLLGRRMPTWELLRD
                     GTPTTSAELLRAGRGVLLDLAGNQHLRRRAVGWTDRVDVVTATRRSEAGDGPAGRAHAV
                     LIRPDGHVAWIAPGSHHDLPMALERWFGPAR"
     gene            9307..9633
                     /locus_tag="C5F59_12895"
     CDS             9307..9633
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225:Polyketide synthesis cyclase (Score: 157.8;
                     E-value: 1.2e-48)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C17/C2-C19 (Score: 189.3; E-value: 1.5e-58)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767153.1"
                     /locus_tag="C5F59_12895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TcmI family type II polyketide cyclase"
                     /protein_id="PPQ57488.1"
                     /transl_table=11
                     /translation="MPSTLIVARMNIESADEVARIFSEFDDTEMPHLMGTRRRELFSYR
                     GLYFHLQDFDGENGGSRIEEAKAHPRFIKVSEDLKPFIEAYDPATWRSPADAMAQRFYH
                     WNGR"
     gene            9630..10910
                     /locus_tag="C5F59_12900"
     CDS             9630..10910
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (8-401). E-value:
                     6.5e-59. Score: 191.7. Matches aSDomain:
                     nrpspksdomains_C5F59_12900_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 483.3; E-value:
                     1.1e-146)"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     772.4; E-value: 2.4e-235)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453026.1"
                     /locus_tag="C5F59_12900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ACP synthase"
                     /protein_id="PPQ57489.1"
                     /sec_met_domain="t2ks (E-value: 5.1e-244, bitscore: 800.5,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQRGRRVVITGIGVTAPGGSGTKGFWQLLTDGRTATRRISLFD
                     SSAFRSQIAAEVDFDAEALGLRPQEIRRMDRAAQFAVTTAREAAVDSGLEFAAVDPART
                     GVSLGTAVGATMGLDEEYRTVSDGGRLELVDHAYAVPHLYSYMVPSSFAAEVAWSVGAE
                     GPVTVVSTGCTSGLDAVGHAADIIREGSADVMIAGAAEAPISPITVACFDAIKATTPRN
                     DDPEHASRPFDASRNGFVLGEGSAVFVLEELESARRRGAHVYAEIAGYATRSNAFHMTG
                     LRPDGAEMAEAIRVAMAEARVNAEDIDYINAHGSGTKQNDRHETAAFKRSLGEAAYRVP
                     ISSIKSMIGHSLGAVGSIELAASALAMEHHAVPPTANLHTADPECDLDYTPLVAREQRT
                     DTVLSVGSGFGGFQSAVVLARPDRSQR"
     aSDomain        9654..10832
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5F59_12900_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="6.50E-59"
                     /label="C5F59_12900_PKS_KS.1"
                     /locus_tag="C5F59_12900"
                     /protein_end="401"
                     /protein_start="8"
                     /score="191.7"
                     /tool="antismash"
                     /translation="VVITGIGVTAPGGSGTKGFWQLLTDGRTATRRISLFDSSAFRSQI
                     AAEVDFDAEALGLRPQEIRRMDRAAQFAVTTAREAAVDSGLEFAAVDPARTGVSLGTAV
                     GATMGLDEEYRTVSDGGRLELVDHAYAVPHLYSYMVPSSFAAEVAWSVGAEGPVTVVST
                     GCTSGLDAVGHAADIIREGSADVMIAGAAEAPISPITVACFDAIKATTPRNDDPEHASR
                     PFDASRNGFVLGEGSAVFVLEELESARRRGAHVYAEIAGYATRSNAFHMTGLRPDGAEM
                     AEAIRVAMAEARVNAEDIDYINAHGSGTKQNDRHETAAFKRSLGEAAYRVPISSIKSMI
                     GHSLGAVGSIELAASALAMEHHAVPPTANLHTADPECDLDYTPLVAREQRTDT"
     gene            10907..12127
                     /locus_tag="C5F59_12905"
     CDS             10907..12127
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (67-401). E-value:
                     2.7e-29. Score: 94.1. Matches aSDomain:
                     nrpspksdomains_C5F59_12905_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 655.9; E-value:
                     3e-199)"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 8|9
                     (Score: 689.2; E-value: 3.4e-210)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453027.1"
                     /locus_tag="C5F59_12905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketosynthase chain-length factor"
                     /protein_id="PPQ57490.1"
                     /sec_met_domain="t2clf (E-value: 2.1e-207, bitscore: 679.3,
                     seeds: 26, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVSTVVTGLGIAAPNGLGLEEYWSATLAGRSGIGPVSRFDASSY
                     PARLAGEIDGFVAEDHLPGRLLPQTDRMTQLALVAAGWALDDAGVVPGDLPEYDMGVIT
                     ASHSGGFEFGQNELRALWSKGGKYVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVVSDQ
                     AGGLDALAQARRQIRKGTPLIVSGAVDASICPWGWVAQLASDRLSHGDVPERAYLPFDD
                     SAAGHVAGEGGALLVLEEESHARARDARRIYGRIAGHAATFDPPRDSGRAPAVQTVIDQ
                     ALADAAVTAEEVDVVFADAAGLPGLDRVEAEAISKVFGPRGVPVTAPKTMTGRLYSGSA
                     PLDVATACLSIRDAVIPPTVHTSPSGRYDIDLVTGAPREATVRYALVIARGYGGFNSAV
                     VVGAPHG"
     aSDomain        11108..12109
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5F59_12905_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="2.70E-29"
                     /label="C5F59_12905_PKS_KS.1"
                     /locus_tag="C5F59_12905"
                     /protein_end="401"
                     /protein_start="67"
                     /score="94.1"
                     /tool="antismash"
                     /translation="PQTDRMTQLALVAAGWALDDAGVVPGDLPEYDMGVITASHSGGFE
                     FGQNELRALWSKGGKYVSAYQSFAWFYAVNSGQISIRNGMRGPSGVVVSDQAGGLDALA
                     QARRQIRKGTPLIVSGAVDASICPWGWVAQLASDRLSHGDVPERAYLPFDDSAAGHVAG
                     EGGALLVLEEESHARARDARRIYGRIAGHAATFDPPRDSGRAPAVQTVIDQALADAAVT
                     AEEVDVVFADAAGLPGLDRVEAEAISKVFGPRGVPVTAPKTMTGRLYSGSAPLDVATAC
                     LSIRDAVIPPTVHTSPSGRYDIDLVTGAPREATVRYALVIARGYGGFNSAVVV"
     gene            12211..12483
                     /locus_tag="C5F59_12910"
     CDS             12211..12483
                     /NRPS_PKS="Domain: ACP (13-83). E-value: 3.8e-13. Score:
                     41.4. Matches aSDomain: nrpspksdomains_C5F59_12910_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129:acyl carrier protein (Score: 108.9; E-value:
                     1.6e-33)"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 121.1; E-value: 3.4e-38)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268987.1"
                     /locus_tag="C5F59_12910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="actinorhodin polyketide synthase"
                     /protein_id="PPQ57491.1"
                     /sec_met_domain="PP-binding (E-value: 1.1e-10, bitscore:
                     32.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEQTVFTVDALKQILRDGAGADESAALDGDILDTSFDALGYESL
                     ALLETASRIERAYDISLDEEAFGEAVTPRALIDLVNSHLPVEQSA"
     aSDomain        12250..12459
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5F59_12910_ACP.1"
                     /evalue="3.80E-13"
                     /label="C5F59_12910_ACP.1"
                     /locus_tag="C5F59_12910"
                     /protein_end="83"
                     /protein_start="13"
                     /score="41.4"
                     /tool="antismash"
                     /translation="QILRDGAGADESAALDGDILDTSFDALGYESLALLETASRIERAY
                     DISLDEEAFGEAVTPRALIDLVNSH"
     gene            12555..13340
                     /locus_tag="C5F59_12915"
     CDS             12555..13340
                     /NRPS_PKS="Domain: PKS_KR (7-164). E-value: 5.2e-13. Score:
                     41.1. Matches aSDomain:
                     nrpspksdomains_C5F59_12915_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     254.2; E-value: 2.1e-77)"
                     /gene_functions="biosynthetic-additional (t2pks) KR C9
                     (Score: 477.4; E-value: 2.5e-146)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015792183.1"
                     /locus_tag="C5F59_12915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketoacyl reductase"
                     /protein_id="PPQ57492.1"
                     /sec_met_domain="adh_short (E-value: 2.8e-38, bitscore:
                     122.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNDVSRVALVTGATSGIGLAVSRLLAQQGHRVYLCARTQESVTR
                     TVKQLQSEGLSVDGTVADVGSKEDVRHLVESAVARFGAIDVLVNNAGRSGGGVTADIAD
                     ELWLDVINTNLNSVFYLTREVLTAGGMRKKDRGRIINIASTAGKQGVVLGAPYSASKHG
                     VVGFTKALGNELAPTGITVNAVCPGYVETPMAQRVRAGYAAAYDASEEQIMEKFTAKIP
                     LGRYSTPEEVAGLVGYLASDPAAPITAQALNVCGGLGNF"
     aSDomain        12576..13046
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5F59_12915_PKS_KR.1"
                     /evalue="5.20E-13"
                     /label="C5F59_12915_PKS_KR.1"
                     /locus_tag="C5F59_12915"
                     /protein_end="164"
                     /protein_start="7"
                     /score="41.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGATSGIGLAVSRLLAQQGHRVYLCARTQESVTRTVKQLQS
                     EGLSVDGTVADVGSKEDVRHLVESAVARFGAIDVLVNNAGRSGGGVTADIADELWLDVI
                     NTNLNSVFYLTREVLTAGGMRKKDRGRIINIASTAGKQGVVLGAPYSASKHGV"
     CDS_motif       12582..12650
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C5F59_12915_0001"
                     /evalue="6.90E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="C5F59_12915"
                     /protein_end="32"
                     /protein_start="9"
                     /score="21.9"
                     /tool="antismash"
                     /translation="LVTGATSGIGLAVSRLLAQQGHR"
     gene            13382..14329
                     /locus_tag="C5F59_12920"
     CDS             13382..14329
                     /NRPS_PKS="Domain: Polyketide_cyc2 (7-149). E-value:
                     4.2e-17. Score: 54.7. Matches aSDomain:
                     nrpspksdomains_C5F59_12920_Polyketide_cyc2.1"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (158-312). E-value:
                     9.9e-13. Score: 40.5. Matches aSDomain:
                     nrpspksdomains_C5F59_12920_Polyketide_cyc2.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 447.2; E-value:
                     5e-136)"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C7-C12
                     (Score: 487.5; E-value: 2.9e-149)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050070.1"
                     /locus_tag="C5F59_12920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclase"
                     /protein_id="PPQ57493.1"
                     /transl_table=11
                     /translation="MTEQEAREVEHEITVRAPAEDVYRLLAEVENWPRLFPPSVYVDYA
                     EKNGNEERIRIWATANGEAKHWTSRRELDPEGRRITFWQEVSAPPVARMSGTWIIEPQG
                     PEQTRVRLLHTYRAIDDDPEGLAWIDRAVDRNSRAELPALKENLELASLSADLTLSFED
                     TVRIDGSAKDVFAFINEAQLWTERLPHVHDVTLTESTPGVQTLRMDTVAKDGSTHTTES
                     VRVCFPDHRIAYKQTTLPALMKLHTGYWQFSEGDDGVTTATSQHTVTVDVENIAKVLGP
                     AAGVAEARAFLREALGTNSRATLGHAKAFAEARR"
     aSDomain        13403..13828
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5F59_12920_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="4.20E-17"
                     /label="C5F59_12920_Polyketide_cyc2.1"
                     /locus_tag="C5F59_12920"
                     /protein_end="149"
                     /protein_start="7"
                     /score="54.7"
                     /tool="antismash"
                     /translation="EVEHEITVRAPAEDVYRLLAEVENWPRLFPPSVYVDYAEKNGNEE
                     RIRIWATANGEAKHWTSRRELDPEGRRITFWQEVSAPPVARMSGTWIIEPQGPEQTRVR
                     LLHTYRAIDDDPEGLAWIDRAVDRNSRAELPALKENLE"
     aSModule        13403..14317
                     /domains="nrpspksdomains_C5F59_12920_Polyketide_cyc2.1"
                     /domains="nrpspksdomains_C5F59_12920_Polyketide_cyc2.2"
                     /incomplete
                     /locus_tags="C5F59_12920"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        13856..14317
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5F59_12920_Polyketide_cyc2.2"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="9.90E-13"
                     /label="C5F59_12920_Polyketide_cyc2.2"
                     /locus_tag="C5F59_12920"
                     /protein_end="312"
                     /protein_start="158"
                     /score="40.5"
                     /tool="antismash"
                     /translation="LSFEDTVRIDGSAKDVFAFINEAQLWTERLPHVHDVTLTESTPGV
                     QTLRMDTVAKDGSTHTTESVRVCFPDHRIAYKQTTLPALMKLHTGYWQFSEGDDGVTTA
                     TSQHTVTVDVENIAKVLGPAAGVAEARAFLREALGTNSRATLGHAKAFAE"
     gene            14333..16300
                     /locus_tag="C5F59_12925"
     CDS             14333..16300
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 409; E-value:
                     5.2e-124)"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 531.3; E-value: 5.5e-162)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453032.1"
                     /locus_tag="C5F59_12925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="monooxygenase"
                     /protein_id="PPQ57494.1"
                     /transl_table=11
                     /translation="MGTTRDADVLVVGAGPVGLLLAGDLAGSGAGVIVLEQLSAPTAES
                     KASILHARTREIFAARGILDRMGTVPDGGRGHFGGIPLDLREADPEHPYAGQAEYLQSR
                     LEPVLQDWAAERGAVVRRGHRVTALVRQSDGVELETVGPDERPRRLTARYVVGCDGTRS
                     TVRQLAGFDFAGDSATREMLRADVAGIDVPDRRLRRYPRGTATSYRRGDGTTRLMVHAR
                     AATPGTGRPGFAEVVAAWAQVTGEDIGSGEPRWLDRFDDTRRQATRYRQGRVLLAGDAA
                     HAQMPVGGQALNLGLQDAAALGPRLAARVSGAADDHVLDDYHRERHAAGARTLTNIQAQ
                     SLLLFGGQEVDGARDVFRELLDLAPVRRHLARTISGLDTPYRPPAERRSRSTPSPQESS
                     TMSRLTGKNALVTGSSRGIGRATAVRLAREGALVAVHYASNEAAADETVAQIEREGGRA
                     FPVRAELGVAGDVHELFLGLEQGLKERTGETTLDILVNNAAVTGVDGILPEDVTAEQLD
                     RYYAVNAKAPFLLVQRAVRNMPDGGRIINISSGLTRCAVPEQVAYSMTKGALEQITLHM
                     AKHLAPRGITVNSVAPGITDNGGAVFDIPEIVEQMAQSSAFKRVGEAGDVADVVTFIAT
                     DESRWITGAFIDASGGTLLG"
     gene            16434..17180
                     /locus_tag="C5F59_12930"
                     /pseudo=""
     CDS             16434..17180
                     /NRPS_PKS="Domain: PKS_KR (1-143). E-value: 6.3e-08. Score:
                     24.5. Matches aSDomain:
                     nrpspksdomains_C5F59_12930_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     185.4; E-value: 2.1e-56)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     134.0; E-value: 1.8e-41)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453033.1"
                     /locus_tag="C5F59_12930"
                     /note="incomplete; partial in the middle of a contig;
                     missing start; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /product="dehydrogenase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RVALVTGANKGIGRAVAGQLGALGMRVYLGARDDERGRAAERDLR
                     AEDLDVRFVRLDVTDETSVTLAAKHIGEESGRLDVLVNNAGTGAPVGAPSETAVQDVRS
                     TFETNVFGTIAVTNAMIPLLRRSEAGRIVNVSSVLGSLTHAAAREDPSGVFPPGVFPAV
                     LDYNTSKAALNAITVTYANELRDEGILVNAVSPGFVATDINGHRGHLTTEQGARLPVRM
                     ATLGADGPTATFVGEDGTPAGQRLAW"
     aSDomain        16437..16862
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5F59_12930_PKS_KR.1"
                     /evalue="6.30E-08"
                     /label="C5F59_12930_PKS_KR.1"
                     /locus_tag="C5F59_12930"
                     /protein_end="143"
                     /protein_start="1"
                     /score="24.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGANKGIGRAVAGQLGALGMRVYLGARDDERGRAAERDLRA
                     EDLDVRFVRLDVTDETSVTLAAKHIGEESGRLDVLVNNAGTGAPVGAPSETAVQDVRST
                     FETNVFGTIAVTNAMIPLLRRSEAGRIVNVSSVLGSLT"
     CDS_motif       16443..16496
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C5F59_12930_0001"
                     /evalue="4.10E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="C5F59_12930"
                     /protein_end="21"
                     /protein_start="3"
                     /score="9.8"
                     /tool="antismash"
                     /translation="LVTGANKGIGRAVAGQLG"
     gene            17218..18789
                     /locus_tag="C5F59_12935"
     CDS             17218..18789
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 717.3; E-value: 2e-217)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511400.1"
                     /locus_tag="C5F59_12935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylmalonyl-CoA carboxyltransferase"
                     /protein_id="PPQ62300.1"
                     /transl_table=11
                     /translation="MDDVPQATGASALLDRLSELKGQAWDGPGPQATERQHAKGKLTAR
                     ERIALLLDKGSFTEVETLRRHRATGFGLEHKRPYTDGVVTGWGTVEGRTVFVYAHDFRI
                     FGGALGEAHAEKIHKLMDMAVSVGAPLVSLNDGAGARIQEGVSALAGYGGIFRRNTRAS
                     GMVPQISVMLGPCAGGAAYSPALTDFVFAVRGISQMFITGPDVVKTVTGEDISQDGLGG
                     ADVHSGVSGVAHFAYDDEETCLAEVRYLLSLLPSNNRELPPPAATTDPADRRCDALIDL
                     VPADGSRSYDIRAVIEELVDDGEHMEVHSTWAPNLVCALARLDGQVVGIVANQPAAMAG
                     VLDIRASEKGARFVQFCDAFNIPLVTLVDVPGFLPGVEQEHEGIIRRGAKLLYAYCNAT
                     VPRISVVLRKAYGGAYIVMDSRSIGADLALAWPGNEIAVMGAEGAANVVFRKEIAAAAD
                     PEAVRRRKIDAYRQELAHPYYSAERGLVDDVIDPRDTRSVLINSLAMLRSKDSELPRRK
                     HGNPPQ"
     gene            18804..19040
                     /locus_tag="C5F59_12940"
     CDS             18804..19040
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946704.1"
                     /locus_tag="C5F59_12940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="PPQ57495.1"
                     /transl_table=11
                     /translation="MTGPTGPAGPPRQELLRVERGHPDAEELAALTAVLLVRTAAVRDT
                     ATVHGPSPAGARWRRPERTPAFANPRAWRRETG"
     gene            19053..20303
                     /locus_tag="C5F59_12945"
     CDS             19053..20303
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 137.5; E-value:
                     7.3e-42)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130977.1"
                     /locus_tag="C5F59_12945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="PPQ57496.1"
                     /transl_table=11
                     /translation="MNPKHTSTPPDADADPGSWGARWWTLLFVLSGNMVLDAVEVSVVL
                     VALPSIGADLGLSLLSVQWLMSGFALGFAALLTLGPRVNARFGRRRAYLGAMLVFAAAS
                     VAGGFAESEGPLIATRVVKGFCAALTAPTGLAIISTTFQEGPGRRRAVSVYSLFGAVGF
                     TVGVLLSAVALESSWRWTFLFPAPVALLLFFLAMRLIPRDPDPARVPSRGLAPLLRDGW
                     LVRSGLGAATLNGTYAGMLLLVTFLLQERWGWSPWQCALALLPACVPLAVAVPFAGRLV
                     GRFGTARLTAAGALAPVIGCGLCLWRIADGGYWTAVLPMLLLVEAGFVLSFAALNMQAT
                     STVEAADRARAVPLYQTGVQLGGVLTLPLVALLMTVYDGYSAALSLLTAVGTVGFLIAL
                     TGLRRDAAVPTRPATPS"
     gene            20266..20901
                     /locus_tag="C5F59_12950"
     CDS             20266..20901
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950145.1"
                     /locus_tag="C5F59_12950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="PPQ57497.1"
                     /transl_table=11
                     /translation="MRPCPPVPPPLPRKGRPVQEQPLRLAVVVGSVRDGRFAPAVADWF
                     ALRTRTRDDFEIDVIDPADHCLPLSMPSALPPEAAASRDGLSARLAAADAFVVVTPEYN
                     HTFPAALKNLLDWFLSEWAAKPVGFVSYGGMAGGLRAVEHLRQVFAELHAVTVRDGVSF
                     HNPWQEFADHGGPRDAAAAEGAAKTMLDQLAWWGEALRRARRQHPYSR"
     gene            20913..21554
                     /locus_tag="C5F59_12955"
     CDS             20913..21554
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450404.1"
                     /locus_tag="C5F59_12955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="PPQ57498.1"
                     /transl_table=11
                     /translation="MPRQISLAMPDLRRTDATSVFVAQVYVPGRASGLETAAHLAEQWS
                     RPGRPSSVLSFSCYLSTGEDTVLTYVQCDDGDSYHPFVRSLEGAAQWPAVEYRLRRSVR
                     PAGNDGPPACVVVATFDVDGAERQDRVIDSLSDAIEGMPADRTEGMISANFHVSTDASR
                     VLNYAEWTSDEAHTAFLGSTTREATKRASGGIPGVRPIGFKRYHLLHGIR"
     gene            21551..22285
                     /locus_tag="C5F59_12960"
     CDS             21551..22285
                     /NRPS_PKS="Domain: ACPS (102-166). E-value: 3.1e-17. Score:
                     54.6. Matches aSDomain: nrpspksdomains_C5F59_12960_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060:4'-phosphopantetheinyl transferase (Score: 208.6;
                     E-value: 1.3e-63)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803992.1"
                     /locus_tag="C5F59_12960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="PPQ57499.1"
                     /transl_table=11
                     /translation="MIDELLPACVAAAHTFGDVADADLLPEELRHMAGAVERRRRSFRT
                     GRHCARQALASLGRTARHPLLPGPHGEPLWPRGVVGSITHCEGYRAAAVAEDRDLASLG
                     IDAEPHAALPAGVLRKVMSPHEGGRLARLFGLHPEVHWDRLLFSAKEAVYKTWFPLTGT
                     GLGLQDIEVTIAPGLRGSAVGARGATGSGAGAGTGAFHAHVPRSRIGAGRLSVLRGHWL
                     VRDGLLVTAAIRTREEQTVESW"
     aSDomain        21857..22048
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5F59_12960_ACPS.1"
                     /evalue="3.10E-17"
                     /label="C5F59_12960_ACPS.1"
                     /locus_tag="C5F59_12960"
                     /protein_end="166"
                     /protein_start="102"
                     /score="54.6"
                     /tool="antismash"
                     /translation="LGIDAEPHAALPAGVLRKVMSPHEGGRLARLFGLHPEVHWDRLLF
                     SAKEAVYKTWFPLTGTGLG"
     gene            22490..23290
                     /locus_tag="C5F59_12965"
     CDS             22490..23290
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 168; E-value: 4e-51)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037154.1"
                     /locus_tag="C5F59_12965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA-binding response regulator"
                     /protein_id="PPQ57500.1"
                     /transl_table=11
                     /translation="MSHDLDLLCRAHPAPQPPPRTPRPPLGRRDLTAVESWTILVVCGD
                     TRAAQSLADELSWHGHTVRPVTTGAAALEEHHSVDLILLDLALPDVDGLQVCRTIAAQS
                     DIPILAVTGRSTELDRVLGLQAGADDYVTEPYGVRELLARMAAVMRRARPRPRTAPRTR
                     VGPLVIERETREVRLHGCLVPLTRKEFDLLQLLASQPGTIFPRRQLLQQIWHDTDVTRS
                     RTIDTHVNSLRRKLGSSQWVLTVRGVGFSLSERLAPSSVAMRCP"
     gene            complement(23238..24584)
                     /locus_tag="C5F59_12970"
     CDS             complement(23238..24584)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 275.3; E-value: 1.4e-83)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890073.1"
                     /locus_tag="C5F59_12970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="PPQ57501.1"
                     /transl_table=11
                     /translation="MTASLRVRNFRLFTLGQLASVTGTWMMFTAQDWLVLRMSDDSAGA
                     LGLVTAAQFTPVLLLTLLGGRLADRYDKRKLLIAANGLLALLALALAAVVLSGQPRLWH
                     IVVCALGIGVVNAVEIPARMAFVSEMVGSDLLPNASALSAAYFNSARVLGPAAAGILIH
                     VWGVPTVVLLNAVSYLGTLVALLRMRPSELHRSGARPARGGVAAGLRYIRGRPDLLLPL
                     LLVAVIGLVGFNFQVTLPLLAKTVFGTGSATFGLLTAAMAAGSLVAALMTTLRRGRPSE
                     RTVLLGAGAFALCELCSALAPSLPVALVALGFTGLAMMVFAQAANHRLQLGTAPSYRGR
                     VMALYTLVHQGTTPLGALLTGRLVERSGARTGLGVAGAVCLVAVLVAWGVSIAVRAGRR
                     ERPKETTAEAPQGVTAADPYDGLPTGTASGPEVRDSAWRPRKERAFRRG"
     gene            complement(24608..25528)
                     /locus_tag="C5F59_12975"
     CDS             complement(24608..25528)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450398.1"
                     /locus_tag="C5F59_12975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="PPQ57502.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.8e-16, bitscore:
                     49.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 8.9e-09, bitscore: 26.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPERPSAASVPPAPYPSAAEEGVQGRAVELSGYGVPLSGLIALPG
                     RTAPRAVVVALHGGGMRAGYFHGRADPGASLLTLAARHGYAALALDRPGYGRSAERVPH
                     GMGLAEQAAVVRGALAGYRRSHPCGAGFFLVGHSLGGKVALTTAAGWRKGGLLGVDVSG
                     ISDRWAVSPTRLTGPGARGTHGLHWGPLALYPPRTFELAAPLIAPLPRREAEEAPYWPS
                     TFAAIAPRIRVPVRFTFAEHERWWRCDARTVREMTARLASPLVRTERLEGAGHNISLGN
                     AARTYHHRVLDFLAMCHRPPRAAPA"
     gene            complement(25531..26355)
                     /locus_tag="C5F59_12980"
     CDS             complement(25531..26355)
                     /NRPS_PKS="Domain: PKS_KR (3-88). E-value: 1.7e-07. Score:
                     23.1. Matches aSDomain:
                     nrpspksdomains_C5F59_12980_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     68.9; E-value: 7.9e-21)"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     39.8; E-value: 9.2e-13)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450401.1"
                     /locus_tag="C5F59_12980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oxidoreductase"
                     /protein_id="PPQ57503.1"
                     /transl_table=11
                     /translation="MKNIVIQGGTDGMGRALARTYLNRGDAVLVIGRSEAKGQAFLAEA
                     NAAGAGSRAAFLQADLSLVSENDRVVEEIGERFPVVDALVLCARHYLSPRRDTAEGIES
                     SLALFYLSRYLLSHGLRGHLEKADRPVIVNVAGPGSPMGEIHWDDLQLKRNYHGLDAQM
                     QGGKANDLLGVSFASLYDGGRTRYVLFNPGSVSTSFSGEYDAATKGHIEGMKRMAKSVE
                     AGIAPIVTCLDSPPAEPLSAFVEGRRMSLDHPSFRLADALRLDELTRELLGR"
     aSDomain        complement(26092..26346)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C5F59_12980_PKS_KR.1"
                     /evalue="1.70E-07"
                     /label="C5F59_12980_PKS_KR.1"
                     /locus_tag="C5F59_12980"
                     /protein_end="88"
                     /protein_start="3"
                     /score="23.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="IVIQGGTDGMGRALARTYLNRGDAVLVIGRSEAKGQAFLAEANAA
                     GAGSRAAFLQADLSLVSENDRVVEEIGERFPVVDALVLCA"
     gene            complement(26472..28409)
                     /locus_tag="C5F59_12985"
     CDS             complement(26472..28409)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs)
                     SMCOG1041:transcriptional regulator, SARP family (Score:
                     464.7; E-value: 1.1e-140)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:PF03704.15"
                     /locus_tag="C5F59_12985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="PPQ57504.1"
                     /transl_table=11
                     /translation="MHFAVLGPVEVRGENGPCAPTSPMARQVLLLLLAHANRVVPLEKL
                     VEELWGDSPPRLARKTVQTYIYQVRKALREGERTGDRPRVATEPRGYRIRVEKGEFDLW
                     RFQELCRQGQAAQMKGDAFTTSAACDEALSLWRGQPFSGVSVGTVLAAHQARWEDLRMG
                     TLEHRIEADMTLGRHRELLSELKGLAVDFPLNEVICGQLMRAAWHSGQRQVALDAFSRL
                     RVAMVDELGLEPSATVKEVQQDILQDGLGPTTRPLTPAPAPAEESCPATSPAELPAKMA
                     DCVAQEHEVAAILAALGEDEDQRSAVPVALVTGGTGTGKTVTAVQAAHHMRPAYPGGQL
                     FTTLHHPDGTPVPTRNALASLLLSSGHSEHGLPDSTEDMARLFRSWTSTQRMLVVLDDA
                     HSREQVLPLLPSSPGCAVIVSSRRHLEGLPGKVTGVSLSGMTGDEGVALLGGLIGTRRV
                     ARELHAARELVQLYHGLPLAVRALGRRLSAWPQLPLADLLRRALRDPGRLAVLEGPQDD
                     GLHRLRSAHLRLPRDEQQLLHLLCRLPQPLGEHVLLRAVEASGQSVVSLRRRLESLADA
                     HFIQFHHLGGRTHFRVPELTRLVVLSGDGAGASALRAPARGLPEQAPGPRPMTPSQADR
                     RENEPCGSFQ"
ORIGIN
        1 tcacgcgggg taggggttcg cctcccgcgc cgtccgcagg gcgcccgccc accaggccag
       61 ctgctcgaac agcgttttgg cgtatccggg gacctcgggg ccgagggggc ggccgtcctc
      121 ccacgccgtg tagtagtccg ggaaggcgag accgtcccgg atcgtcacgg cgtgcagttc
      181 ggtcagcacg ttctccaggt gcagcaccgc gtgccggccc cccgccgccc cgccgtagct
      241 gacgaaggcc acgggcttgg ccgcccactg ggtgaagtgc cagtcgatcg ccgccttcag
      301 cgatgccgga taactgtggt tgtactccgg cgacaccacg acgaacgcgt cagcgccctc
      361 cagggccgac gtcagggccg ccatcccggc cggacggggg taatcgtccc cggcgtactt
      421 cggcgaggcc gccggcagct ccaagggaat gtcgatatcg gccagatcga cggtcttcac
      481 atcgaacccc ccgtgattca ccgcctgttc ggcgacccag gaggccacga ccggtccgaa
      541 ccgtccttcg cggacgctgc cgacgagaat caccagtctg tacgtgtcgt tgtccatgcc
      601 caccacgatc cggcggctct gcggccgcaa ccagaccgtg cccaggctgg cccccgcagg
      661 gccaccctgg agcctctgcc gtccgtgcgc gccgccctat cctcggacca tggggacgcc
      721 gttgggagat ttcatccggg ccaagcgtga cagcatccag ccgcagtcgc tggggctgcc
      781 ggaccacgga cgccgcaggg caccggggct gcggcgttcg gacctcgcgg ggcgggccgg
      841 tatcagcgtg gagtacctga cccgtctgga gcagggccgc gaccgcaacc cgtcggtcgc
      901 ggtggtgaac gcggtcgccg acgcgctcgg tctcgacacc gcggagcgca gccatctgcg
      961 ctacctcgtg aagatcaccg gcggggagtg caccgcccac acccggccct caccggcgcc
     1021 ccgcgaggtc cgtccgccgg tcctggagac gttgcgcctc ctcgaaccgg gcatcgccgt
     1081 ggtgaccaac cggctgggcg acgtcctggc ccgcacaggt gcgtacgagg cggtgacgag
     1141 cgggaccggg ctgctcgact ccgactcccc gaacctcacc cgctacgtct tcaccgaccc
     1201 ccgcgcccgg atgttcttcg ccgactggga cgacgtcgcg gacgagcagg ccttcgacct
     1261 gtggttcgcc ccgtccgtcg agaacaccga gtggttcacc gcggaactcg cccccgtcgc
     1321 cggccccgac ttcacgggcc gcctgaacgg ccatgtggtt ccgcgacgcg gggtgctgcg
     1381 cctcaaccac ccgtccgggg aggaactccg gctgctccgc gagacgctcg acctctcctc
     1441 ggacgcacag caactggtcg tcctcctccc cgcggacgag gggacggccc aggcggtcgc
     1501 ccggctccgc tccctgccgc cgcacggccg gctccgcgcc atctcgtaga gcatccctgg
     1561 ccacgcctta cgccgtcgtg ccccctacgc ggcgctcgcg gtgtcgcggt gcccgggcgg
     1621 cgtgccctcg gccctcgccc cgtgcttcag ggcgacgggg gcgggggcgg gaacgggggc
     1681 actcagcagc cccgccgtca gtgccttgcg tacggcgtcg agccgggaga cggctcccaa
     1741 tttccggaac gcggagtgca ggtgccgttt caccgttccc agggtgatgc ccagcctgct
     1801 ggcgatctgc tggttggtca tggcggcggc cgcacagcgc accacctgca actcacgcgg
     1861 ggagagcgcg atcgggctct ccctggcggc gtcgctcttc gccggagtgg cgaggtagcg
     1921 cgcggcggcc agcagcgcgc ccgcaccggc gtccctggcg agaacgacgt gcgctccggc
     1981 ctccagcaga gccgtccggt cacccgcccg gtagggcgga atgaccaaca gggccgaacg
     2041 agggtgggcg cggcgcaggg acctgatcgt gctgaccgaa tcgttcagta tttcggaggg
     2101 ctccagaacg atgacatggg gactttgatc ggcaaccagt tgcaacgcct ccaccctgtg
     2161 cagcgtggcc cccaggagaa gaatatcctc ttgcgcgtga agtattccgg cgaccgaatc
     2221 ccgaaccaac gcatggttgg ctgcgaaaac catacggatg ggcgccccgg agaccgttgt
     2281 cgacctgcat gaatcctccc ggagcggcag gtgaacgctg ggggaaggcg gcgagggtgg
     2341 gatgtgagga gtcttttcgg atccgctccg aggtattccc gataagctct tccctgtttc
     2401 ggcaacctcg gtcacgactt cccccattgc agttcccatg gcatctacag caagaacgca
     2461 gaaacgttac caaaacggcg ggcccgtctg tcaacaagtt tatttcgagg tgcggtggag
     2521 tcgagttgat acggatatga acgaaagcgc ctgaccggct cgccaagatt tcatgctgtc
     2581 atcgggattt catgaatggg aaacccggtt caattgtttt cggccacctc gcacacacgg
     2641 gagacgtcac cacgggaccg acccggagcc gtcgaaggaa aaccaccggc gggggcttcg
     2701 atccggtcag tgccgtctcg acggaccgtg cacccgaggg cgaccgggcg gcgggcaccc
     2761 tccggcccgg ggcccctgct cgctccggtc gtccgggtgg cggtcatccg cgcccccctg
     2821 ccgcacccgc gccgtcggca tcgctgaacc ggaccgcggg ggtggatgcc gccggggagt
     2881 acgcgtggag gaacgtacgc accgccgctt cgaccacgtc gtccagttcg ccctcgggca
     2941 gggggcgggt gcccagcacg gaccgggcct ccgccggacc ggtgagcagc gcgaggaact
     3001 gctcggccgc cacgtccgga tcctgggtgc gcagcctgcc cgccagggcc agccgggcga
     3061 ggcggtcggc cagggtctcc acgagacgcc gacccccctg gcgctgcacg gactccagca
     3121 ggtcggggaa cctggcggcc tcggcgtaca ggagtcgccg cagggcccag gactcgtcgg
     3181 cgcagtggca ccgcagcagc agccggcccg tctccgtcag cgcgttcccg acatcgcccg
     3241 agggctcccg caaggggtcc agcgcggcga ggttgcggtc ggccgtgcgt acggccaccg
     3301 tctccatcgc ctcacggaac agggactcct tgtcgtgcat gtggttgtag atggtgggct
     3361 tcgcgacacc tgcctcagcc gcgatctcct gcacgcagga ctgtccgtag ccctcccgtg
     3421 cgaagacgcg gaaggccgcg tcgaggatcg ctcgtcgctt gtcgatgcgc ccgcgcgatg
     3481 cgttgcgccg gggcgcctcg gacgttctgg cttcagtcac caactcatcc taccgccgaa
     3541 gccttctaga tgaaccgatt agtacaagtt gttgggctgc gcggttgcac aacgccgagc
     3601 gaggccgcta gcttgaacca cctggttcaa aagagcttcc gtcacgttcg tactggagta
     3661 gcgtctatgt ctcaagctca ggacgaccgc ctggatccca ggctgttacg gctgatcggt
     3721 gtggtcctgc tgggcgggat catgggaatc ctcgacagca cgatggtggc cgtggccgcc
     3781 gacaccctct ccgaggagtt caacacttct ctgacggcga tcagctgggc ctccaccgcc
     3841 tatctgctga ccctcaccgt caccatcccc gtcaccagct gggcgatcgg ccggttcgga
     3901 gtcaagaagc tgtggctctt cggcctcgtg ctcttcctcg ccggttccct ggcctccgcg
     3961 ctcgcctgga acgtggagag cctgatcgtc ttccgcgtcc tgcagggcct cggatccggt
     4021 gtgctcgatc cgctcgtgct ggtgatcctc gcccgcgcgg caggccccag ccgggccgga
     4081 cgcgtcatgg gaatgatggg cgtcgtgctc tccctgggcc cggtgctcgg tcccgtactg
     4141 ggcggcgtgg tcctcgaagc cctggactgg cgctggatgt tcttcatcaa cctgcccatc
     4201 ggcgtcgtcg ccttcttcct ggccacccgt gtcatcccgg cggacccgaa ggccgcgcag
     4261 cagtccggca ccggcctcga cgtgctcggc ttcgccctga tggcccctgg attcgccgcc
     4321 atggtgctcg gcctcaccca ggcgggagag cacgccacct tcggtacgcc caccgtgctc
     4381 gtgccgctcg gtctcgggct ggtgctgctc gtcgcgtacg tgctgcacgc gctgcgggcc
     4441 cggcggaccc cgcccctgat cgacgtccgt ctcttcagca gccgcagctt cgccgcgagc
     4501 gtgacggtcc agggccttgt cggactcgcc acctacgcgg gcctgttcgc gctgccgctc
     4561 tactaccagc tgctgcacgg acacgacgcg cgcgcggccg ggctgctggt cgccccgctg
     4621 gggctcggct cggcgctggc catgcccctc gccggacggc tcagcgaccg catgggggcc
     4681 aggaacctcg cagcgggcgg cgcggtcatc gccggtctcg gcggggtcgc cctcactcag
     4741 atcggcgccg acaccaccga actcctctcg gcactcggcg cgttcgccat cggcctcggt
     4801 ctcggcgcgg tcggcgcccc caccatgggc gcgctctacc gcacgctccc cccggagaag
     4861 gtcccccagg gcagctcggt gctgtacaac ctcaaccagc tcggcggcgc cttgggcgtc
     4921 gcgggggtcg ccctcatcct ggcgaccatg aacgcggaca agggctccac cgccgacgct
     4981 gtcagcggct tccacggggt gtactggttc gtgaccgcgg tctccgtggt catcctcctc
     5041 gccaccccgc tgcttcccgg ccgcccggag gcgccggccg caccggcggg ggaaacgccg
     5101 acaggggaag caccggcgaa ggagaccgca ggccgagcgg gctgacgggc ttgacggagc
     5161 ccgggcgggc cgggagagca gggcgccggt ccggcgggcc ttccgcagga ccggcgccgg
     5221 gtcccggcag aacgtacggc acgaccccga gtgccgcccc tgcgagggcg gtcctcagtc
     5281 gtgtgcgccg gcgcactcgc cgaccggtac cgcggccggg caggcggtcg agtgcccgtg
     5341 gccccgtcca cggcggccgc ggccggatcc aggacgcgca cccgcaccgc cgaccgggcg
     5401 gcgagccttc gccggcgcac ggcgaccctc ctgacgacgg gacgctccac cagcgtgtgg
     5461 agcttccacg cgcacagcag cgagacggcg aacgcaccca ggaccaccgc cgcggccacc
     5521 ggggtcgacc ggctcctgtc cgctccgagc aggcgatgcc cgtacaccag gacgaggccg
     5581 tgcaccatgg agaagccgaa ggagacctcg ccgagccaga tcggcaggcg gccggcggac
     5641 ggggcgccac gctcctgggc cttcaggtcg gcctgggtca ccgctgcgac cagcagggcg
     5701 agcggtatca cgggcagagc caccaggctg tacaggtacg gcgcgtggca ggcgagccag
     5761 tagctgccga cgaccggagc ggcaacgggc agcacccgca gacgcggcat gaggccctcg
     5821 cgcacgagcc gcgcggtgag gatcccgagg aggaactcca gcatccgggt ggccggcagg
     5881 acgtagacga acctgaactg atggacgtcc gtcaccccgt cgggcatcgc cgcgacgggc
     5941 ccggcgggca gattccgcgc gatcagcggg accgcggcga cgaccagtac gaccgacgcc
     6001 gccgagcccc acagatacct gggcccgatc cgtgacaccc agcgccacga ctgctgtgac
     6061 caggtgattc gggtacacct tcgcgactct tcgctgccag aacccgcgcg gggtgtcggt
     6121 ggggcgggcc gtccgggcga ggacgaatcc gctgagtacg aagaaggacg agaccccgat
     6181 ccatcccgcc ttctgaagac gtcgaagaac ccgttctgca ccgtggaatc ggcgaagaaa
     6241 ccttccaccg ctgcgtgcgg gcctcactcc ggcgacggac agccccgacg aaccggcgca
     6301 cagaacgctc ggcgtgggga aagggggccg agtgtggcag ccggtgttca aggaacggtc
     6361 aacgcgccag gggcccaaga ggctctcgac aagcagcggg agccggccgc gacaccctcc
     6421 gccggggctc ccttgaacgg gccttggccg atcgttggtc cgttgctgcg acgctcggtg
     6481 agcacggaag cacggcccgg aaaggccggg ctgccgcccc ttccattcag ctcccgagga
     6541 gattccgcgt atgactgcgc agcacccccc tgttgtggaa gagccctcca tcggccaggt
     6601 catgggaatt ctgagcggct actggcacac gaagatcctg ctgaccgcga cggaggcgga
     6661 cctcttcacc gttctgtccg gcgggtcggc caccgcggag gaactggccg accggctgag
     6721 gttccggctg ccgggagcct ccgacttcct tctcgccctg gcgggaatcg gcctgctgga
     6781 ggccgcggag gacggcacct tccgtaactc cgccgccgcg gaggccttcc tggtgagcgg
     6841 tcgccccggc tacgtcggcg gatatctgaa gttctgcgac cgcgaactga acccggcgtg
     6901 ggacggtctc ggggagtcgc tgcgtaccgg gcttccccgc aacgccgccg cgcgggaggg
     6961 caatccgtac cacaccctct accaggacac ggaggccacg gactccttcc tggagagcat
     7021 ggacatgctc aacaccccga tcctggaacg ggtgggtgca ctcgactgga gcccgtacga
     7081 gtccttcgtc gacgtcggcg gcgcgcgggg caacctcgcc catcacctga ccggcgccca
     7141 cccgcacctg aagggggccg tgttcgacct gccgccgctg gcggaggcct tcggcacaca
     7201 catgaaggcg ctcggcggcg gagacgggat cgcattccac ggcggggact tcttcagcga
     7261 cccgctgccc ggagccgatg tgatcgttct cggacacgtg ctccacaact ggggcccgaa
     7321 ggaccgtgcg gcactgctcc gcaccgccta cgacgcggtg cgccccggcg gggcggtact
     7381 cgtctacgac cccatggtca gcaacagccg accgccgctc tacgccacgc tggccagtct
     7441 cagcatgctc gtctggtccg ccggcggcgg cgagtactcg gtggccgagt gccatgccct
     7501 gatgaaggaa gccgggttcc gccccgagac cgtcggcccc gaggacaccg tcgacgacgt
     7561 gctggtgctg ggccacaagg accgctgagt gcggccccgc gacattcgcc ctggatgcac
     7621 ggccggcccg ggaacggacg agaggagcgg cacatggacg catcagtcgt agtcgtagga
     7681 gctggaccgg ccgggctcat gctcgccggg gaactgcgcc tggccgggat cgacgtggtg
     7741 gtcctggaga aactggcacg gagcacaggc gagtcccgcg gcatcgggtt caccccgcgc
     7801 accatggagg tgttcgacca gcggggactt ctgtcccgct tcggcgacat cgagaagagc
     7861 ggccagggac acttcggcgg cattccgctg gacttcgagg tcctgggcgg aggggaactg
     7921 gcggccagat cggtgccgca gtccgtcacc gagagcgtcc tggaagcatg ggcgcgtgaa
     7981 ctcggggccg acatccgccg gggccacgaa ttcgccgggc tcacggacca cggggaccgg
     8041 gtcgacgtcc gggtgcgcga ctcgggccac gagcacaccc tgagcgccgc ctacctggtc
     8101 gggtgcgacg gaggccgcag cggcgtgcgc aaggccggcg ggttcgactt cccgggcacc
     8161 gccgccacca ccgagctctt cctcgcggac gtacgcggtg tcgacctgga gccgcgcatg
     8221 gtggccgacc gggtgaccga cggcatggtg atggtgggac ggctcggcga cggcgtgcac
     8281 cgcatcatcg tcagcgagcg cggcgcaccg ccgcagcgtc gtaccggccc gcccgccttc
     8341 gccgaggtcg cggacgtgtg gaagcggctc accggaatcg acatctcgca cgccgagccg
     8401 gtctgggtca gcgccttcgg cgacgccagc cggcaggtca ccgaataccg cagggggcgg
     8461 gtcctgctct cgggcgactc cgcgcacatc catctgccgg ccggtggcca gggaatgaac
     8521 accagcgtcc aggactcggt gaacctcggc tggaagctgg ccgcggtgct gcgctccacc
     8581 gcacctcccg cgctgctgga cacgtaccac agcgagcgcc acgaggtcgg acggcgcctg
     8641 ctcgccaaca cacgcgccca gagcctgctg ctcctgggca gtgaggacgt gcagccgctc
     8701 cgcgacatgc tcgccgaact cgccctgcac gaggaggtga gccgcaccct cgcggccaag
     8761 gcggcgggac tggacatccg ttacgacgtc ggcaaggggg tcaacccgct gctcggccgg
     8821 cggatgccca cctgggagct tctgcgggac ggcaccccca ccaccagcgc ggaactgctc
     8881 agggcaggcc ggggcgtgct cctcgacctg gccggcaacc agcacctgcg gcgacgtgcc
     8941 gtcggctgga cggaccgggt cgacgtcgtg acggccaccc gccggagcga agcaggggac
     9001 ggaccggcgg gccgggcgca cgcggtcctg atcaggcccg acgggcacgt cgcctggatc
     9061 gcgcccggca gccaccacga tctgccgatg gcgttggaac gctggttcgg accggccagg
     9121 tgagattccg ggagcacggg agaccccggg cccacgtgac gcggtccgga cgaggttccg
     9181 ccggcagcgg gacgcggtag ccgcacccac cggacgccgc gacgcgacac ggcacccacg
     9241 ccacgcagcg cccgacacac gccgcacgca ggtgcgcaga gcacacgtgt gcagagagaa
     9301 ggaacgatgc caagcactct gatcgtcgcg cggatgaaca tcgaatcggc ggacgaagtc
     9361 gcccggatct tctcggagtt cgacgacacg gaaatgccgc acctgatggg gacccgacgc
     9421 cgggagctgt tctcctaccg cggcctgtac ttccacctcc aggacttcga cggggagaac
     9481 ggcgggtcgc ggatcgagga ggccaaggcc cacccgcggt tcatcaaggt cagtgaggac
     9541 ctgaagccgt tcatcgaggc ctacgacccg gccacctggc gctcgccggc cgacgccatg
     9601 gcccagcggt tctaccattg gaacggaagg tgagcgcgca gcggggccgg cgggtcgtca
     9661 tcaccggtat cggtgtcacc gcccccggcg gctccggaac caagggcttc tggcagctgc
     9721 tcaccgacgg ccggacggcc acccgccgga tctccctctt cgactcctcg gcgttccgct
     9781 cccagatcgc cgccgaggtg gacttcgacg cggaggcact cgggctgcgc ccgcaggaga
     9841 tccgccggat ggaccgcgcg gcacagttcg ccgtgacgac cgcccgcgag gccgcggtgg
     9901 acagcgggct tgagttcgcc gccgtcgacc cggcccgtac gggagtctcc ctcggcaccg
     9961 cggtcggcgc gacgatgggc ctggacgagg agtaccgcac cgtcagcgac ggcggccgcc
    10021 tcgaactcgt cgaccacgcc tacgccgtac cgcacctcta cagctacatg gtccccagct
    10081 cgttcgccgc cgaggtggcc tggtccgtcg gcgccgaggg gccggtcacc gtggtctcca
    10141 ccggctgcac ctccgggctc gacgcggtcg gccacgcggc ggacatcatc agggagggct
    10201 ccgccgacgt catgatcgcc ggcgccgccg aagcaccgat ctccccgatc acggtcgcct
    10261 gcttcgacgc gatcaaggcc acgacgcccc gcaacgacga ccccgagcac gcctcgcggc
    10321 ccttcgacgc gagccgcaac ggcttcgtcc tcggtgaggg gtccgccgtg ttcgtactgg
    10381 aggaactgga gagcgcccgg cgccggggcg cccatgtgta cgccgagatc gccggctacg
    10441 cgacccgttc caacgccttc cacatgaccg gcctgcgccc cgacggcgcg gagatggccg
    10501 aggccatccg ggtggccatg gcggaggcac gggtgaacgc cgaggacatc gactacatca
    10561 acgcgcacgg atccgggacc aagcagaacg accggcacga gacggcggcg ttcaagcgga
    10621 gcctgggcga ggccgcgtac cgggtgccca tcagctccat caagtccatg atcggccact
    10681 cgctcggcgc ggtcggctcc atcgagctgg ccgcctccgc gctggccatg gagcatcacg
    10741 cggtgccgcc cacggccaat ctgcacaccg cggacccgga gtgcgacctc gactacacgc
    10801 cgctggtcgc ccgcgagcag cggaccgaca ccgtgctgtc ggtcggcagc ggattcggcg
    10861 ggttccagag cgcggtggtg ctcgcccggc ccgacaggag tcagcgatga acgtcagcac
    10921 agtggtgacg ggcctgggaa tcgccgcgcc caacgggctg ggcctggagg agtactggtc
    10981 cgccaccctc gcgggccgca gcggcatcgg cccggtgtca cgcttcgacg cctcctccta
    11041 cccggcccgg ctcgcgggcg agatcgacgg cttcgtcgcc gaggaccatc tgccggggcg
    11101 gctcctgccc cagaccgacc ggatgacaca actcgccctg gtggccgccg gatgggcgct
    11161 ggacgacgcg ggcgtcgtgc ccggcgatct ccccgagtac gacatgggtg tgatcaccgc
    11221 cagccactcc ggcggattcg agttcggcca gaacgaactc agggcgctgt ggagcaaggg
    11281 cggcaagtac gtgagcgcct accagtcctt cgcctggttc tacgcggtca acagcggcca
    11341 gatatccatc cgcaacggca tgcgggggcc gagcggtgtc gtcgtcagcg accaggcggg
    11401 cggcctcgac gcactcgccc aggcccggcg gcagatccgc aagggcacac cgctgatcgt
    11461 ctccggcgcc gtcgacgcgt ccatctgccc ctgggggtgg gtggcccagc tcgcgagcga
    11521 ccggctcagc cacggcgacg tacccgagcg cgcctacctg cccttcgacg actccgcggc
    11581 cgggcacgtg gccggcgagg gtggagccct gctcgtcctg gaggaggaga gccacgcccg
    11641 cgcccgggac gctcggcgga tctacggccg gatcgcgggc cacgccgcca ccttcgaccc
    11701 gccgcgggac agcgggcggg cccccgccgt gcagacggtg atcgatcagg cgctggcgga
    11761 cgccgccgtc accgcggagg aggtggacgt ggtcttcgcg gacgccgccg gcctgcccgg
    11821 cctcgaccgg gtggaggccg aggcgatctc caaggtgttc ggcccgcgag gggtgccggt
    11881 gacggctccc aagaccatga ccgggcggct ctactcgggg tcggcgccgc tggacgtggc
    11941 gaccgcctgc ctcagcatcc gggacgcggt gattccgccc accgtgcaca cctcgccctc
    12001 gggccggtac gacatcgacc tggtgaccgg cgccccacgc gaggcgaccg tgcggtacgc
    12061 gctcgtgatc gcccgcggat acggcggctt caactcggcg gtcgtcgtcg gcgcaccgca
    12121 cggctgacga aggagagccg gagcgcggag acggataccg ccacgacacc tcctgtacac
    12181 acccacccct ctcggagagc aggaacagcc atgcccgaac agaccgtctt caccgtggac
    12241 gcgctcaagc agatcctgcg cgacggagca ggagcggacg agagtgccgc cctcgacggc
    12301 gacatcctcg acacctcctt cgacgcgctg ggctacgagt ccctcgcact gctcgaaacg
    12361 gccagccgca tcgagcgggc gtacgacatc agcctggacg aggaggcgtt cggcgaggcg
    12421 gtcacgcccc gcgcgctgat cgatctcgtc aactcacacc tgccggtcga gcagtccgcc
    12481 tgaggcccgg ggcccgagtg acgagctccg agttccccac gcacacccgc cgatccaccc
    12541 aggagacgaa gagcatgacg aacgacgtga gcagggtcgc cctcgtgacc ggagcgacca
    12601 gtggaatcgg tctggccgtc agccgcctgc tggcacagca gggacaccgg gtctacctgt
    12661 gcgcgcgcac gcaggagtcc gtgaccagga ccgtcaagca gctccagagc gagggactgt
    12721 ccgtggacgg aaccgtcgcc gacgtgggct cgaaggagga cgtcaggcac ctcgtggaga
    12781 gcgccgtggc ccgtttcggg gccatcgacg tcctggtcaa caacgccggc cgcagcggcg
    12841 gcggcgtgac cgccgacatc gcggacgagc tgtggctgga cgtgatcaac accaacctca
    12901 acagcgtctt ctacctcacc cgtgaagtcc tgacggcggg cggcatgcgg aagaaggacc
    12961 gaggacggat catcaacatc gcttccacgg ccggaaagca gggagtcgta ctgggcgcgc
    13021 cgtactccgc ctcgaagcac ggagtcgtcg gcttcaccaa ggcgctcggc aacgagctcg
    13081 cgccgaccgg catcaccgtc aacgccgtct gccccggcta tgtggaaacc cccatggcac
    13141 agcgggtccg ggcgggttat gccgccgcgt acgacgcgag cgaggagcag atcatggaga
    13201 agttcacggc caagatcccg ctcggccgct actccacgcc cgaggaggtc gcgggcctcg
    13261 tcggctatct ggcctccgac cccgccgccc cgatcaccgc gcaggcactg aacgtgtgcg
    13321 gcggtctggg caacttctga tccggccggg caaccagcca ccacacagca gggagttgac
    13381 catgaccgag caggaagccc gcgaagtcga gcacgagatc accgtccgag cacccgccga
    13441 ggacgtctac cgtctcctcg ccgaggtgga gaactggccc aggctcttcc ccccgtccgt
    13501 gtacgtggac tacgcggaga agaacggcaa cgaggagcgc atccggatct gggccaccgc
    13561 caacggcgag gcgaagcact ggacctcacg ccgtgagctc gaccccgagg gccgccgcat
    13621 caccttctgg caggaggtgt ccgcgccgcc ggtggcgcgg atgagcggca cctggatcat
    13681 cgaaccgcag ggccccgagc agacccgggt gcggctcctg cacacctatc gggcgatcga
    13741 tgacgatccc gaagggctcg cctggatcga ccgggccgtg gaccgcaaca gcagggcaga
    13801 actgcccgca ctgaaggaga acctggagct cgcctcgctc tccgccgacc tgacgctgtc
    13861 cttcgaggac accgtgcgga tcgacggatc ggccaaggac gtcttcgcgt tcatcaacga
    13921 ggcccagctg tggaccgagc ggctcccgca cgtgcacgac gtcacactga ccgagagcac
    13981 tccgggcgtc cagaccctcc ggatggacac cgtcgccaag gacggctcga cccacaccac
    14041 ggaatcggta cgggtctgct tccccgacca ccggatcgcc tacaagcaga cgacgctgcc
    14101 ggcgctgatg aaactgcaca ccggctactg gcagttcagc gagggtgacg acggtgtcac
    14161 caccgccact tcccagcaca cggtgacggt cgacgtcgag aacatcgcga aggtcctcgg
    14221 tcccgccgcc ggagtggcgg aggctcgcgc gttcctgcgc gaggcgctcg ggaccaacag
    14281 ccgggccact ctggggcacg ccaaggcctt cgccgaagca cggcgctgac ccgtgggcac
    14341 cacgcgcgac gcggacgtgc tcgtcgtggg cgcaggcccg gtggggctcc tgctggccgg
    14401 cgatctggcc ggcagcggcg ccggagtgat cgtgctggag cagctcagcg ccccgaccgc
    14461 cgagtccaag gcgtcgatac tgcacgcccg tacgcgagag atcttcgccg cccgcggcat
    14521 cctcgaccgg atgggcaccg tcccggacgg cgggcgcggc cacttcgggg gcattccact
    14581 cgatctgcgg gaggcggacc cggagcatcc gtacgccgga caggccgagt acctgcagag
    14641 ccggctcgaa cccgtactgc aggactgggc cgcggaacgg ggcgccgtgg tgcgccgcgg
    14701 gcaccgcgtc accgcgctgg tgcggcagtc cgacggggtg gagctggaga cggtggggcc
    14761 ggacgagcgg ccccggcgcc tcacggcacg ctacgtcgtc gggtgcgacg gtacccggag
    14821 cacggtacgg cagctcgccg gcttcgactt cgcgggcgac tccgccaccc gggagatgct
    14881 ccgcgccgac gtggcgggca tcgacgtccc cgaccggcga ctgcgccggt acccccgggg
    14941 aaccgcgacc tcctaccgcc gcggcgacgg caccacccgg ctgatggtgc acgcacgagc
    15001 cgcgaccccc ggcacgggca ggcccggatt cgccgaggtc gtggcggcat gggcacaggt
    15061 gacgggcgag gacatcggca gcggggagcc gcgctggctc gacagattcg acgacacgcg
    15121 gcgccaggcc acccgttacc gccaaggccg cgtcctgctg gcaggcgacg cggcccacgc
    15181 gcagatgccc gtcggcggac aggcgctcaa cctgggactg caggacgcgg ccgccctggg
    15241 cccccggctc gccgcacggg tgtcgggcgc cgccgacgac cacgtactgg acgactacca
    15301 ccgcgaacgc catgcggcgg gcgcccgcac gctgaccaac atccaggccc agtcgctgct
    15361 gctcttcggc ggtcaggagg tcgacggggc acgggacgtc ttccgggagc tcctggacct
    15421 cgcccccgtc cgccggcacc tcgcccgcac gatcagcggc ctggacaccc cctaccgccc
    15481 tccggccgag cgccggagcc ggtccacccc ctcaccgcag gagagctcca ccatgagcag
    15541 gctcacgggc aagaacgcac tggtcaccgg ctccagccgg ggcatcgggc gggccaccgc
    15601 cgtacggctg gcgcgcgaag gcgccctggt cgcggtgcac tacgcgagca acgaggcggc
    15661 ggccgacgag acggtcgccc agatcgaacg ggaaggcggc cgcgccttcc ccgtacgcgc
    15721 cgaactcggc gtcgccggcg acgtccacga gctcttcctc ggcctggagc agggcctgaa
    15781 ggagaggacg ggggagacca ccctcgacat cctcgtcaac aacgcggccg tcaccggagt
    15841 ggacggcata ctccccgagg acgtcaccgc cgagcagctc gaccgttact acgcggtgaa
    15901 cgcgaaggct ccgttcctcc tcgttcagcg ggcggtcagg aacatgccgg acggcggcag
    15961 gatcatcaac atctcgtccg gtctcacccg ctgcgccgtg ccggagcagg tcgcgtactc
    16021 gatgaccaag ggtgccctgg agcagatcac cctgcacatg gccaaacacc tcgccccgcg
    16081 cggcatcacc gtcaacagcg tggcaccggg aatcaccgac aacggcggag cggtcttcga
    16141 catccccgag atcgtggagc agatggcgca gagttccgcc ttcaagcgcg tgggcgaggc
    16201 cggggacgtc gcggacgtgg tgaccttcat cgccaccgac gagtcgcgct ggatcaccgg
    16261 cgccttcatc gacgcgagcg gcgggacgct cctcggatga gccgtcctcg gtgcacccgt
    16321 atccgggccc tggcccgtac ccacaccgcg gggtccgcga ggcaccgggc ccggttcccg
    16381 accgaaggag acctgtgacc acccagcccg ctccgcacat cccgtccggc acccgcgtgg
    16441 cactcgtgac cggtgccaac aaaggcatcg gtcgggccgt cgccggacaa ctcggcgcgc
    16501 tcggcatgcg cgtctacctg ggcgcccgcg acgacgaacg cgggcgcgcc gccgagaggg
    16561 acctgcgcgc cgaggacctc gacgtccgct tcgtcaggct cgacgtcacg gacgagacct
    16621 ccgtgaccct tgccgccaag cacatcggcg aggaatcggg ccgcctggac gtgctggtca
    16681 acaacgccgg caccggcgcc cccgtgggtg cccccagcga gacggcggtg caggacgtgc
    16741 gcagcacgtt cgagacgaac gtcttcggca ccatcgcggt gacgaacgcg atgatcccgc
    16801 tgctgcgccg ctcggaggcc ggacgcatcg tgaacgtcag cagcgtcctg ggctccctca
    16861 cccacgccgc ggcacgggag gacccgtcgg gtgtcttccc gccgggcgtc ttccccgcgg
    16921 tgctcgacta caacacctcc aaggccgccc tgaacgccat caccgtgacg tacgcgaacg
    16981 agctgcgcga cgagggaatc ctggtgaacg cggtgtcccc cgggttcgtc gccaccgaca
    17041 tcaacggcca ccgcggacac ctcaccacgg agcagggagc ccgccttccc gtacggatgg
    17101 cgacccttgg cgcggacggg ccgaccgcca ccttcgtcgg tgaggacggc acgccggccg
    17161 gacagcggct ggcctggtga aggacgtacg tgacgacagg acgggagcgt gaggatcttg
    17221 gacgacgtac cgcaggccac cggggcatcc gccctgctgg acaggctgtc ggagctcaag
    17281 ggacaggcct gggacggccc cggcccgcag gccaccgaac gacagcacgc caagggcaaa
    17341 ctcacggcgc gcgagcgcat cgcactgctt ctcgacaagg gcagcttcac cgaggtcgaa
    17401 accctgcgca ggcaccgggc gaccggcttc ggactggagc acaagcggcc gtacaccgac
    17461 ggtgtggtga ccggatgggg aacggtcgag ggccggacgg tcttcgtcta cgcccacgac
    17521 ttccgcatct tcgggggtgc gctcggcgag gcccacgcgg agaagatcca caaactgatg
    17581 gacatggccg tctccgtggg cgcaccgctc gtctcgctca acgacggggc gggcgcccgg
    17641 atccaggaag gcgtgtccgc cctggccggg tacggaggca tcttccgcag gaacacccgg
    17701 gcttcgggga tggtcccgca gatcagtgtg atgctggggc cgtgcgcggg aggcgccgcc
    17761 tactcgccgg ccctcaccga cttcgtcttc gcggtccgtg gcatctcgca gatgttcatc
    17821 acaggccctg acgtggtcaa gacggtgacc ggcgaggaca tctcgcagga cggcctcggc
    17881 ggcgccgacg tccacagcgg cgtctccggg gtggcccact tcgcctacga cgacgaggag
    17941 acctgcctgg cggaagtgcg ctacctgctg tcgctgctgc cgtccaacaa ccgcgaactg
    18001 cccccacccg ccgccaccac ggacccggca gaccgtcgct gcgacgccct gatcgacctc
    18061 gtccccgccg acgggagccg gtcgtacgac atccgggcgg tcatcgagga actcgtcgac
    18121 gacggcgagc acatggaggt ccattccacc tgggccccca acctggtgtg cgccctcgcc
    18181 aggctggacg gccaggtggt gggcatcgtc gcgaaccagc cggccgcgat ggcgggggtg
    18241 ctggacatca gggcctccga gaagggggcg aggttcgtcc agttctgcga cgcgttcaac
    18301 atcccgctcg tcactctcgt cgacgtcccc ggtttcctcc ccggagtgga gcaggagcac
    18361 gaggggatca tccggcgggg cgccaagctg ctgtacgcct actgcaacgc gaccgtgcca
    18421 cggatctcgg tggtgctccg caaggcgtac ggcggcgcgt acatcgtgat ggactcccgc
    18481 tcgatcggcg ccgacctcgc gctcgcctgg ccgggcaacg agatcgccgt catgggcgcg
    18541 gagggtgcgg cgaacgtggt cttccggaag gagatcgcgg cggccgccga cccggaggca
    18601 gtgcgccgcc ggaagatcga cgcctacagg caggagctgg cgcacccgta ctactcggcg
    18661 gagcgcgggt tggtcgacga cgtcatcgac ccccgggaca cccggtccgt gctcatcaac
    18721 tcgctcgcca tgctgcgcag caaggactcc gagctgccgc gccgcaaaca cggcaacccc
    18781 ccacagtgaa caggagcccg aggatgactg gaccgaccgg accggcagga ccgccgcgac
    18841 aagaactcct gcgggtggag cgggggcacc ccgacgccga ggagctggcc gcgctcaccg
    18901 ctgtgctgct cgtccgcacc gcggccgtac gcgacaccgc gaccgtgcac ggcccgtccc
    18961 ctgccggcgc ccgctggcgc cgaccggagc ggacaccggc cttcgcgaac ccacgggcct
    19021 ggcgccggga aaccggctga agtggcgggg aaatgaatcc gaagcacacg agcaccccgc
    19081 cggacgcgga cgccgatccg gggagttggg gcgcccgctg gtggaccctg ctgttcgtcc
    19141 tctccgggaa catggtgctg gacgccgtcg aggtctccgt cgtcctcgtc gcactccctt
    19201 ccatcggcgc cgacctcggt ctctccctcc tgtcggtgca gtggctgatg agcggcttcg
    19261 cgctcgggtt cgccgcgctg ctcacgctcg gcccccgggt caacgcacgt ttcggaagaa
    19321 ggcgtgcgta cctcggggcc atgctggtct tcgcggcggc ctcggtggcg ggcgggttcg
    19381 cggaaagtga aggaccgctg atcgcgaccc gggtggtcaa ggggttctgc gcggcgctca
    19441 ccgcgcccac cgggctggcc atcatcagca ccaccttcca ggaggggccc gggcggcgtc
    19501 gggcggtctc ggtgtactcc ctgttcggcg cggtcggatt caccgtcggg gtgctgctct
    19561 cggcggtggc cctggaatcc agctggcgct ggaccttcct ctttcccgcc cccgtcgccc
    19621 tcctgctgtt cttcctcgcg atgcggttga ttccgcggga cccggacccg gcgcgggtgc
    19681 cgtcgcgcgg actcgcgccg ctcctccgcg acggatggct cgtacgctcg gggctgggcg
    19741 ccgcgaccct caacgggacc tacgccggga tgctgctcct ggtcaccttc ctcctgcagg
    19801 agcggtgggg ctggtccccc tggcagtgcg ccctcgcgct gctgcccgcc tgcgtgccac
    19861 tggccgtggc cgttcccttc gccggccggc tcgtcggcag gttcggtacg gccaggctta
    19921 cagcggcggg ggccctcgct ccggtcatcg gctgcgggct gtgcctgtgg aggatcgcgg
    19981 acggcggcta ctggaccgcg gtgctgccca tgctcctcct ggtcgaagcc gggttcgtcc
    20041 tctcgttcgc cgcactgaac atgcaggcca cgtcgacggt cgaagccgcc gaccgggccc
    20101 gcgccgtccc gctctaccag accggagtac agctcggcgg tgtgctgacg ctgccgctgg
    20161 tcgcgctgct gatgacggtg tacgacggct actccgccgc gttgtccctg ctcaccgcgg
    20221 tgggaacagt ggggttcctc atcgcgctca ccgggctccg ccgcgatgcg gccgtgccca
    20281 cccgtcccgc caccccttcc taggaaaggc cgacccgtgc aagagcaacc gctcagactg
    20341 gcagtcgtcg tcgggagcgt ccgcgacggc aggttcgcgc ccgccgtggc cgactggttc
    20401 gccctgcgga ccaggacgcg ggacgacttc gagatcgatg tgatcgatcc ggccgaccac
    20461 tgtctgccgc tgtccatgcc gtccgcgctg ccgccggagg ccgccgcgtc gcgggacggg
    20521 ctgtccgcca ggctcgcggc ggcggacgcc ttcgtggtgg tgacgcccga gtacaaccac
    20581 accttccccg cggcgctgaa gaacctcctc gactggttcc tctcggaatg ggcggccaag
    20641 cccgtcgggt tcgtgtccta cggcggcatg gcgggcgggc tgcgggcggt ggagcacctg
    20701 cgccaggtct tcgccgaact gcacgcggtc acggtgcgcg acggtgtcag cttccacaac
    20761 ccctggcagg agttcgctga tcacggagga ccccgcgacg ccgcggccgc cgagggcgcg
    20821 gccaagacga tgctcgacca actcgcctgg tggggagagg ccctgcgccg ggcacgacgc
    20881 cagcacccct actcgcgttg aacggagccg acatgcctcg tcagatctct ctcgcgatgc
    20941 ccgacctgcg caggaccgac gccacctcgg tgttcgtcgc gcaggtgtac gtgcccggca
    21001 gggcgagcgg gctggagacg gccgcacatc tggccgagca gtggagccgc ccggggcgcc
    21061 cctcgtcggt cctctccttc agctgctacc tcagcacggg cgaggacacc gtgctgacct
    21121 acgtccagtg cgacgacggg gattcctacc atcccttcgt ccgctcgctg gagggagccg
    21181 cgcaatggcc ggcggtggag taccggctgc gcaggagcgt acgaccggcg ggcaacgacg
    21241 ggccgccggc ctgcgtggtc gtcgccacct tcgacgtcga cggggcggaa cgccaggacc
    21301 gggtcatcga ctcgctgtcc gacgcgatcg agggcatgcc ggccgaccgt accgaaggca
    21361 tgatctccgc gaacttccat gtgagcaccg acgccagccg cgtcctcaac tacgcggagt
    21421 ggacctcgga cgaggcccac acggccttcc tcggcagcac gacccgggaa gcgaccaagc
    21481 gggccagcgg cggcatcccg ggggtgcggc ccatcggctt caagcgctac cacctgctgc
    21541 acggcatccg gtgatcgacg agctgctgcc cgcctgcgtc gcagcggccc acaccttcgg
    21601 cgacgtggcg gacgcggacc tcctccccga ggagctgcgc cacatggcgg gtgcggtgga
    21661 gagacggcgc aggtcgttcc gtacgggacg gcactgtgcc cggcaggccc tcgcctcact
    21721 gggccgtacc gcccgccatc cactgctgcc ggggccccac ggggaaccgt tgtggccccg
    21781 cggcgtcgtc ggcagcatca cccactgcga gggctaccgg gcggccgcgg tggccgagga
    21841 ccgggacctg gcctctctcg gcatcgatgc cgaaccgcac gccgcgctgc ccgcgggggt
    21901 gctccgcaag gtcatgtccc cgcacgaggg tggacggctg gcccggctct tcggcctgca
    21961 tcccgaagtg cactgggacc ggctgctgtt cagcgccaag gaggccgtct acaagacctg
    22021 gttccccctg accggcaccg ggctcggtct ccaggacatc gaggtgacga tcgcccccgg
    22081 cctccgcgga agtgctgtag gcgcccgcgg tgccacgggt tccggggccg gcgcggggac
    22141 gggtgccttc cacgcccacg tgccgcggtc ccgtatcggg gcggggcggc tgtccgtcct
    22201 gcggggacac tggctggtgc gcgacggcct gctggtcacc gcggcgatcc gcaccaggga
    22261 ggagcaaacg gtcgaatcct ggtgaaactc ctccggccga aaaccggggt caaccttggt
    22321 gctattcgcg gctcctggcc acttcccgca tggcacgctg cgacgtgccg caaccgatgg
    22381 cgtgcgcaac ggcgcgctgc gagcatcggt ccccgctccg gatcctcccg gagcgtccga
    22441 cagcgattgg cctgcccata cccatcaagt gaagtcacag gagaagaaca tgtcgcacga
    22501 cctcgatctg ctgtgccggg cccaccccgc cccgcaaccc ccaccgcgca ctccgaggcc
    22561 gcccctgggg cggcgcgacc tgacggccgt ggaatcctgg accattctgg tggtgtgcgg
    22621 ggacacgcgg gcggcgcagt ccctcgccga cgaactgagc tggcacggcc acacggtcag
    22681 accggtcacg acgggcgccg ccgccctgga ggagcaccac agcgtcgacc tcatcctgct
    22741 ggacctcgcc ctgccggacg tggacggcct gcaggtctgc cgcaccatcg ccgcacagag
    22801 cgacatcccc atcctcgccg tcaccgggcg cagcaccgaa ctcgaccgtg tcctggggct
    22861 ccaggcggga gcggacgact atgtgacgga gccgtacgga gtgcgtgagc tgctcgcccg
    22921 catggccgcg gtgatgcgcc gggcgaggcc tcgcccccgg accgcgcccc gtacgcgggt
    22981 ggggccgctc gtcatcgagc gggagacccg cgaggtgcgg ctgcacggat gtctcgtccc
    23041 gctcacccgc aaggagttcg acctcctgca actgctggcc tcccagcccg ggacgatctt
    23101 cccccgtcgg cagttgttgc agcagatctg gcacgacacc gacgtgacgc gcagtcgcac
    23161 catcgacacg cacgtcaaca gcctgcgtcg taagctcggt tcgagccagt gggtgctcac
    23221 cgtccgggga gtgggcttca gcctctccga aaggctcgct ccttcctcgg tcgccatgcg
    23281 ctgtccctga cctcgggacc ggaggcggtg ccggtcggca gtccgtcgta cggatcggcc
    23341 gcggtgacgc cttgcggcgc ttcggcggtg gtctccttcg gccgctcgcg tctcccggcg
    23401 cgcacggcga tggagacccc ccacgcgacg aggacggcga ccaggcacac cgccccggcc
    23461 acacccagtc cggtgcgtgc tcctgaccgt tccacgagcc ggcccgtcag gagtgcgccg
    23521 aggggcgtgg tgccttggtg gaccagggtg tagagggcca tcacccggcc gcggtaggag
    23581 ggggcggtgc cgagctgcag gcggtggttg gccgcttgcg cgaacaccat catcgcgagg
    23641 cccgtgaagc ccagcgcgac cagcgccacc gggaggctgg gagccagcgc cgagcagagt
    23701 tcgcacaggg cgaaggcacc ggcgccgagc agcaccgtgc gttcactcgg tctgccgcgg
    23761 cgcagcgtgg tcatcagcgc cgccaccagg gatcccgcgg ccatggccgc ggtcagcagc
    23821 ccgaacgtgg cggacccggt cccgaacacc gtcttcgcga gcagcggcag cgtcacctgg
    23881 aagttgaacc cgaccagccc gatcaccgcc accagcagca gcggcagcag gaggtcgggc
    23941 ctgccccgga tgtaccggag cccggccgcc accccgccgc gggccggccg ggcccctgag
    24001 cggtggagct ccgagggccg catgcgcagg agtgccacca gggtgccgag gtagctgacc
    24061 gcgttgagca gcaccaccgt cggcacgccc cacacgtgga tgaggatccc ggctgccgcc
    24121 ggtcccagta cgcgcgcgga gttgaagtac gccgcgctca gcgcggaggc gttcggcagc
    24181 aggtcggagc ccaccatctc actgacgaac gccatccgtg cgggtatctc caccgcgttc
    24241 accacaccga tgcccagcgc gcagacgacg atgtgccaca gccgcggctg cccggagagg
    24301 accacggccg ccagcgccag ggccagcagc gcgagcagtc cgttcgcggc gatcagcagc
    24361 ttgcgcttgt cgtagcggtc cgccagccgg ccgcccagca gggtgaggag cagtacgggc
    24421 gtgaactggg cggcggtcac caggccgagc gctccggccg agtcgtcgct catccgcagc
    24481 acgagccagt cctgcgcggt gaacatcatc cacgtgcccg tgaccgaggc gagctggccc
    24541 agagtgaaga gccggaagtt gcggacccgt agcgacgccg tcatcctccg caggactgcc
    24601 gttcggctca tgccggagcc gcccgcggag gacggtggca catggccagg aagtcgagga
    24661 cgcggtggtg ataggtgcgg gcggcgttac ccagactgat gttgtgtccc gcgccttcca
    24721 gccgttccgt gcgcaccagc ggcgacgcca gccgtgcggt catctcccgt accgtccgcg
    24781 cgtcgcaccg ccaccaccgc tcgtgctcgg cgaaggtgaa gcgtacgggg acacggatcc
    24841 gcggcgcgat cgctgcgaag gtggacggcc agtacggtgc ctcttccgcc tcccgtcgcg
    24901 gcagaggagc gatcaacggc gccgccagtt cgaaggtccg gggcgggtag agggcgagcg
    24961 ggccccagtg cagaccgtgg gtgccgcgcg cgcccgggcc ggtcagccgg gtggggctga
    25021 ccgcccagcg atcactgatg ccggagacgt cgacccccag cagcccgccc ttccgccagc
    25081 ccgccgcggt ggtgagcgcc accttgccgc ccagtgaatg tcccaccagg aagaagccgg
    25141 ccccgcacgg gtgggagcgc cggtacccgg ccaacgcccc ccggaccacg gcggcctgct
    25201 cggcgagccc catgccgtgg ggcacccttt ccgccgatcg gccgtagccg ggccggtcga
    25261 gggcgagtgc cgcgtacccg tggcgggcgg cgagggtgag cagcgaggcg ccggggtcag
    25321 cccgtccgtg gaagtatccg gcccgcatgc ctccgccgtg cagggcgacc accacggccc
    25381 ggggcgccgt ccgcccgggg agcgcgatga gcccggacag cggaaccccg tagccgctca
    25441 gctcgacggc ccggccctgg acgccttcct ccgcggccga cgggtacggc gccggcggca
    25501 cggacgctgc ggacgggcgc tccggcatgg tcagcggcct agcagttctc gggtcagctc
    25561 gtcgagccgg agggcgtccg ccaggcggaa ggaagggtgg tccaggctca tccggcgtcc
    25621 ctccacgaag gcgctcagcg gctccgccgg aggggagtcc agacaggtca cgatgggcgc
    25681 gataccggcc tcgacggact tggccatccg cttcatcccc tcgatgtgcc ccttcgtcgc
    25741 cgcgtcgtac tcgccggaga agctggtgga gacactgccc gggttgaaca ggacgtagcg
    25801 cgtcctgcca ccgtcgtaca ggctggcgaa ggagacgccc agcaggtcgt tggcctttcc
    25861 gccctgcatc tgcgcgtcca ggccgtggta gttccgcttc agctgcagat cgtcccagtg
    25921 gatctcaccc atggggctgc cggggcccgc gacattgacg atcacaggcc ggtccgcctt
    25981 ctccaggtgt ccgcgcagtc cgtggctgag caggtaccgg ctcagataga agagcgcgag
    26041 actgctctcg atgccctccg cggtgtcccg gcgcggcgac aggtagtgcc gggcgcacag
    26101 gaccagcgcg tccaccacgg ggaaccgttc gccgatctcc tcgacgaccc ggtcgttctc
    26161 gctcacgagg ctcaggtcgg cctggaggaa agcggcccgg gagcctgctc ccgcggcgtt
    26221 cgcctcggcg aggaacgcct gccccttcgc ctcgctcctg ccgatgacga ggacggcgtc
    26281 gccccggttc aggtaggtgc gggcgagggc gcggcccatg ccgtcggtac cgccctggat
    26341 gacgatgttc ttcacggatc tccccgggat ggagcggaac gccacgcttc gcacgcggtc
    26401 ggatgagccg gcatgagatg aaccggtgag ttaaacctaa tgacccagca cgaaaaaggc
    26461 aacgagctcg actactggaa tgaaccgcac ggttcatttt ctctccggtc cgcctgactg
    26521 ggcgtcatcg gacgcggtcc gggcgcctgc tccgggagac cgcgtgcggg agcgcggagc
    26581 gcggacgcgc cagctccgtc cccggagagc acgaccagcc gggtcagctc gggcaccctg
    26641 aagtgcgtcc ggccgcccag gtgatggaac tggatgaagt gtgcgtcggc gagggactcc
    26701 agccgtcggc gcagcgacac cactgactgc cccgacgcct cgacggctcg cagcaggacg
    26761 tgttcaccca gcggctgggg cagtcggcac aggaggtgca gcaactgctg ctcgtccctg
    26821 gggaggcgca ggtgggccga cctgagccgg tgcaggccgt cgtcctgggg accctcgagc
    26881 accgcgagcc gccccgggtc gcgcagggcg cgccgcagca ggtcggccaa gggcagctgc
    26941 ggccacgccg acaggcgccg ccccagcgcg cggacggcca ggggcagacc gtggtagagc
    27001 tggacgagct cgcgggcggc gtggagttcg cgcgcgaccc gccgggtgcc gatgaggcct
    27061 ccgagcagag ccacgccctc gtcaccggtc atgcccgaca ggctcacccc ggtgaccttg
    27121 ccgggcaggc cctcgagatg ccgccgggac gagacgatca ccgcgcagcc aggactgctc
    27181 gggagcagcg gaagcacctg ctcgcgggag tgtgcgtcgt cgaggacgac cagcatccgc
    27241 tgcgtcgacg tccagctgcg gaacagccgt gccatgtcct cggtcgagtc gggcagcccg
    27301 tgctccgagt gacccgaaga caggagcagg gaggccaggg cgttcctggt gggaacaggc
    27361 gtgccgtccg ggtggtgcag cgtggtgaac agctgtccgc cgggataggc gggccgcatg
    27421 tggtgtgcgg cctgcaccgc cgtgacggtc ttgccggtgc cggtgcctcc tgtgaccagg
    27481 gcgacgggca cggccgacct ctggtcctcg tcctcgccga gggcggccag gatggcggcc
    27541 acctcgtgct cctgcgccac gcagtccgcc attttcgcgg ggagttcggc gggggaggtg
    27601 gccgggcacg actcctcggc gggagcgggc gcaggggtga gtggtcgcgt ggtgggcccc
    27661 aaaccgtcct ggaggatgtc ctgttggacc tccttgacgg tggccgaggg ttcgaggccc
    27721 agctcgtcga ccatcgccac ccgaagtcgg ctgaacgcgt ccagggcgac ctggcgctgc
    27781 cccgagtgcc acgccgccct catcagctgg ccgcagatca cctcgttgag cgggaagtcg
    27841 accgcgagtc ccttgagttc actgaggagt tcgcgatggc gccccagggt catgtcggcc
    27901 tcgatgcggt gctccagcgt ccccatgcgc aggtcttccc accgcgcctg gtgcgccgcg
    27961 aggacggtgc ccaccgagac ccccgagaac ggctgccccc tccacaggga gagtgcctcg
    28021 tcgcaggccg cggacgtcgt gaaggcgtca cccttcatct gggcggcctg cccctgccgg
    28081 cagagctcct ggaaccgcca gaggtcgaac tcccccttct ccactcggat ccggtatccg
    28141 cgcggctctg tcgcgacccg tggcctgtcg ccggtcctct ccccttcccg cagcgccttg
    28201 cgcacctggt agatgtacgt ctgcacggtc ttacgggcga gccgtggcgg cgagtcgccc
    28261 cagagctcct cgaccagctt ttcgagcgga accacccggt tggcgtgggc caggagcagt
    28321 agcagtacct ggcgggccat gggagaggtc ggagcgcagg gcccgttctc cccacggacc
    28381 tcgaccgggc cgagaacggc gaagtgcat
//
