LOCUS       BGC0002017             12514 bp    DNA     linear   BCT 19-FEB-2013
DEFINITION  Nocardiopsis potens DSM 45234 contig_74, whole genome shotgun
            sequence.
ACCESSION   BGC0002017
VERSION     BGC0002017
KEYWORDS    .
SOURCE      Nocardiopsis potens DSM 45234
  ORGANISM  Nocardiopsis potens DSM 45234
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsaceae; Nocardiopsis.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 16:43:36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12514
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1476
                     /NRPS_PKS="Domain: AMP-binding (2-385). E-value: 4e-75.
                     Score: 244.7. Matches aSDomain:
                     nrpspksdomains_ctg4_1_AMP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     416.2; E-value: 2.5e-126)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="AMP-binding (E-value: 5.3e-93, bitscore:
                     300.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MHRRLGIGPGDPVVVQLPNVPEVFEVVFALFRLGALPVYALPAHR
                     SAEIGHLHAVTGARALVVSAARGPFDHVRMAREIAAGTGDGPAPHVIGVGAADPGALTE
                     AGAVPLETLRAEAADPAALSDPDPSDVAFFQLSGGTTGLPKLIPRTHDDYLYSVRASAD
                     ICGLTPDTVFLGALPVVHNFPMSSPGFLGVMHAGGSTVLAPDPSPATCLELIERERVTL
                     AAAVPPVAMLWLDAVDGGAQAHRDLSSLRMLQVGGAKFAPEAAKRVAGTLGCRLQQVFG
                     MAEGLVNYTRDEDDEATVTGTQGRPISPGDELRVVGPDGAEVPPGEPGELLTRGPYTIR
                     GYYRAPEHNARAFTPDGFYRTGDVVRVAPSGHITVEGRVKDQINRGGEKIAPDEVEDHL
                     LAHPGVHDAAVVAMPDPYLGERACAYVIPRDGAGDGLDRPALLRFLRGRGLAAYKIPDR
                     VEVVPEFPATGVGKVSKRDLRAAIADAVTAGRH"
     source          1..12514
                     /culture_collection="DSM:45234"
                     /db_xref="taxon:570268"
                     /isolation_source="household dustbin"
                     /mol_type="genomic DNA"
                     /organism="Nocardiopsis potens DSM 45234"
                     /strain="DSM 45234"
                     /submitter_seqid="contig_74"
                     /type_material="type strain of Nocardiopsis potens"
     protocluster    1..12514
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3967:12514]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3968..12514
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..12514
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2223:12514]"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2224..12514
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
     cand_cluster    1..12514
                     /SMILES="NCC(=O)NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="chemical_hybrid"
                     /product="NRP-metallophore"
                     /product="NRPS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..12514
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002017"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..12514
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRP-metallophore"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(VibH_like or Cy_tandem or (cds(Condensation and
                     AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or
                     TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or
                     (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or
                     PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like))
                     or Lys_monoox or VbsL)))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        7..1155
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_AMP-binding.1"
                     /evalue="4.00E-75"
                     /label="ctg4_1_AMP-binding.1"
                     /locus_tag="ctg4_1"
                     /protein_end="385"
                     /protein_start="2"
                     /score="244.7"
                     /specificity="substrate consensus: diOH-Bz"
                     /tool="antismash"
                     /translation="RRLGIGPGDPVVVQLPNVPEVFEVVFALFRLGALPVYALPAHRSA
                     EIGHLHAVTGARALVVSAARGPFDHVRMAREIAAGTGDGPAPHVIGVGAADPGALTEAG
                     AVPLETLRAEAADPAALSDPDPSDVAFFQLSGGTTGLPKLIPRTHDDYLYSVRASADIC
                     GLTPDTVFLGALPVVHNFPMSSPGFLGVMHAGGSTVLAPDPSPATCLELIERERVTLAA
                     AVPPVAMLWLDAVDGGAQAHRDLSSLRMLQVGGAKFAPEAAKRVAGTLGCRLQQVFGMA
                     EGLVNYTRDEDDEATVTGTQGRPISPGDELRVVGPDGAEVPPGEPGELLTRGPYTIRGY
                     YRAPEHNARAFTPDGFYRTGDVVRVAPSGHITVEGRVKDQINR"
     CDS_motif       970..1059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0001"
                     /evalue="1.30E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_1"
                     /protein_end="353"
                     /protein_start="323"
                     /score="20.7"
                     /tool="antismash"
                     /translation="PPGEPGELLTRGPYTIRGYYRAPEHNARAF"
     CDS             1513..2178
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 289.3; E-value: 3.7e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_2"
                     /transl_table=1
                     /translation="MSLPQIAPYEPPAPDRLPDNRAQWRPEPERAVLLVHDMQRYFLRP
                     YAHGAEPLNRATANIARLAAACRAAGVPVVYTAKPGDMPRERRGLEIDFWGSGMRAVPE
                     HTTIDDAVRPEPGDTLLTKWRYSAFAQTDLEQRLAAMGRDQLLVTGVYAHIGCLLTAAD
                     AFMRDIQPFFVADAMADFTAEDHHFAVRYVARRCGVALTTDAALDGVRATDRSTAAAG"
     CDS             2224..3564
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Orn_monoox"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 533.9;
                     E-value: 4.2e-162)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="Orn_monoox (E-value: 1.1e-187, bitscore:
                     612.3, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTTTRTTDAPPVHDLAGIGFGPSNVALAIALRERREQAAADPGRT
                     APTAVFHERQQEFGWHRGMLLDDATMQVSFLKDLVTTRNPASDFSFLSYLHQAGRLHDF
                     INHKTLFPLRSEFHDYLAWCAGRLSDSVRYGSEVIGVEPVRDAAGRISAVDVLAREAGP
                     GGERTHRTRARNLVIAPGLSPRLPEGVRLGERVWHNEYLLHRLEALGEGAAPRSFAVVG
                     AGQSAAEVADHLYRRFPGAEVNAVFSRYGYSPSDDSQFANRIFDPEAVDAFYDASDETK
                     AQIMGYHGNTNYSVVDPDLIESMYRAVYQDRVLGTERLHMHKLSRVTGVEEDADGVTLT
                     VEHLPSGKQRPLRADYVVYATGYHPAAPLSLLGGLAEHVATDARGRHAVGRDYRLITDD
                     EVTCGIYLQGGTEHTHGISSSLLSNVAVRAGEILDSVGARTAGAAAA"
     CDS             3639..3872
                     /NRPS_PKS="Domain: PP-binding (8-73). E-value: 1.4e-10.
                     Score: 33.4. Matches aSDomain:
                     nrpspksdomains_ctg4_4_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_4"
                     /sec_met_domain="PP-binding (E-value: 1.3e-11, bitscore:
                     33.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTDTALTPERIRADVERVLGEQPGTVPGTENLLDLGMDSIRLMSL
                     VESWRTAGAQTDFIELAEEPSIDAWTRLLAGG"
     aSDomain        3663..3857
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_4_PP-binding.1"
                     /evalue="1.40E-10"
                     /label="ctg4_4_PP-binding.1"
                     /locus_tag="ctg4_4"
                     /protein_end="73"
                     /protein_start="8"
                     /score="33.4"
                     /tool="antismash"
                     /translation="ERIRADVERVLGEQPGTVPGTENLLDLGMDSIRLMSLVESWRTAG
                     AQTDFIELAEEPSIDAWTRL"
     CDS             3968..12514
                     /NRPS_PKS="Domain: Condensation_Starter (7-303). E-value:
                     3.8e-97. Score: 317.1. Matches aSDomain:
                     nrpspksdomains_ctg4_5_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (479-876). E-value:
                     9.7e-104. Score: 339.0. Matches aSDomain:
                     nrpspksdomains_ctg4_5_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (989-1058). E-value: 1.4e-22. Score:
                     71.6. Matches aSDomain: nrpspksdomains_ctg4_5_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1074-1377). E-value:
                     3.1e-102. Score: 333.5. Matches aSDomain:
                     nrpspksdomains_ctg4_5_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1543-1938). E-value:
                     2e-107. Score: 351.1. Matches aSDomain:
                     nrpspksdomains_ctg4_5_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2112-2179). E-value: 3e-25. Score:
                     80.1. Matches aSDomain: nrpspksdomains_ctg4_5_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (2204-2516). E-value:
                     1.9e-98. Score: 321.0. Matches aSDomain:
                     nrpspksdomains_ctg4_5_Condensation_LCL.2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     356.3; E-value: 4.9e-108)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_5"
                     /sec_met_domain="Condensation (E-value: 8.2e-68, bitscore:
                     217.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-116, bitscore:
                     376.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.9e-16, bitscore:
                     46.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTDTPHPRFDLTGAQSGVWYAQQVDPSGAVYNVGQYVDLVGDLDT
                     GLLQEALAAVVAETDALRTRIVDDGGVPRQEVLPPGAAGVGRPADAVDLRGEADPEAAA
                     LELMLADMDTPVDLAGGPLHRFALIRTADRRHLWYQRYHHILADAYAISVITRRAAEVY
                     TALAEGADPGRRFGALADVVAEEEAYEASERREEDGGHWARALADRPEPALLSDAPPAT
                     PRRAVRPGARLDAAALSGLEELAGQAGANWAEALIALFGCYVHRRTGAPEAVLGVPAMG
                     RLGSAALRTPAMVVNVLPLRVPAAPGDTVAEAVRRTRDALRALRAHQRYRAEDIRRDLS
                     LVGRATGLYGPMVNIKAFDYDVRFGEVRGDTRTLSEGPVDDVSLSVAADSGAGGLHLVL
                     NANPERYTEQEAADRLAEFVRMVEGLLSRPEPGTGEGGAGAAASARVASLDLVGAAERA
                     LLTAPPEPRPVPEDSVADQVAAAARRAPGAPALRTAESRLDYAGLVRRADAVAARLAAA
                     GAARETVVAIALPRGADLVAALLAASRLGSTYLPIDPDFPADRIAYMLADSGARLLVTT
                     PELDKELPEGPERVLLGPAGPEQADPAPGTADRATTAPAAAARRHGAAYVLYTSGSTGR
                     PKGVVVPERGLLNFLRDMGERFPLGADDRWLAVTTVGFDISALELYLPLMHGAELVLAD
                     RDTVRDPAALADLAERAGATVMQATPALWRALADERPAVLDRLRVLVGGEALPTDLAER
                     LAARAPSVTNLYGPTETTIWSTASRVRPGEPVDIGAPIANTGAYVLDSALRPVPVGVPG
                     DLYISGEGLARGYAGRPDLTAERFVACPFGAPGERMYRTGDVVRRRADGALEYLGRGDH
                     QVKVRGFRIELGEVEVRLGRLPGVAQAVVTAREDVPGQAHLVGYAVFEDGADTDPARLR
                     AALAETLPDYMVPSAFVALDAFPLTENRKIDRKALPAPAGAGAAAGDRPAPDAAPRTPV
                     EERICAVLGEVLGSAPIGVHQDFFALGGHSLLATRAANRIRAELGLHARVRDLFDAPEP
                     ARLAALLQERSGGDDRPPLTAHPGPDDDAPLSYAQERIWFHEELHGPGPAYNVPLAFRL
                     RGPVDAAALALALRDTVARHDVLRTVHADDGEGPRPRVLPMGRVPELLRTEDAGADPAR
                     LDRAVAEVLHTPFDVRTDVPVRAALIRTAPDDAVLALCFHHIATDEWSETPFVRDLDTA
                     YTARTAGEEPRWERPAVRYTDFARWQRSWLGDAADPGSPMGRGLAYWRRALDGLPAETA
                     LPADRPRPAVADGAGATVRFDLDADTAAALRRAAAAHGTTVFMVLQAAVAVLLHRMGAG
                     DDIPVGTPVTNRDDTAVHDAVGMFLNMLTLRTDLSGAPTGRELLARIREADIEAFAHAG
                     VPFEAVVRETDPSRSAARHPLFQVMLTYQREPDHPGLLGTDSSVHPIDIATSKLDLEFT
                     FAEFPGGGGLAANLRYATARFDRATAEGLAERFRQVLIALLVAPDVPVGEHEVLTDAER
                     SALLRGAGATARPVPAPGLARRIARTAAEHPDRTAVRAGSERVGYAELARRADAVAARL
                     AAAGAVRESVVAVALPRGADLVAALLAVGRTGAAYLPIDPDFPADRIAYMLADSGARLL
                     VTTPELDPVLPAGPARLLLGPDAPGGAAASQAAGAVLSFLDPHPDSAAYVLYTSGSTGR
                     PKGVVVPHRALLNFLLDMAERFPLDAGDRWLAVTTVGFDISALELYLPLMQGAELVLAD
                     RDTVRDPAALADLAEESGATVMQATPALWRALAEDRPEALDGLRALVGGEALPRDLAER
                     MAARTAHTANLYGPTETTIWSTVSRVRVGEPVDIGAPIANTGVYVLDASLRPVPVGVPG
                     DLYISGEGLARGYAGRPDLSAERFVACPFGAPGERMYRTGDVVRWRADGALEYLGRGDH
                     QVKVRGFRIELGEVEEALSRAEGVGQAVVTAREDVPGQAYLVGYLVPEPGGADPDPARL
                     RAALAETLPDYMVPSAFVALDAFPLTENRKIDRKSLPSPAVSGAEPSGPRSSSAASAEG
                     PSGGGGSLRAGTGPGRGAPEEGRPSSSGPLRARLLLAPGADGAAGTTESARAAGGEPRD
                     ETEREMCAIAAEVLGLPSLGVHDDFFTSGGHSLAAARTVNRMRARLGLDIGVRDLFEAP
                     TVAGLAARTAARSAASGGDRPAAARPPLARRTDPDAPAPLSAEQRRLWLLDGMNPGSDA
                     YNVPWALRISGPLDRAALAAAARDVLLRHEVLRTRFPLPEGAAEPVQQVVPEDALPADP
                     LRVEEPRTAAPQDGAAGADHRVEAAARAPFDLGSDLPVRFTLFPEGEDEHLLLVVFHHI
                     AVDEWSQAPFLRDLDTAYLARLDGRAPDQAPIPVQYADYAAWQAELLGDGDDPGSAAAR
                     QRAFWAEALAGLPEETALPADRPRPAGGMPADGGVVGFRVPPALRKAAEELAESTGTTR
                     FMVLRTAVAVLLHRMGAGDDVALGAPAANRTDEALHDLVGMFLNTLVLRTDLSGDPGFT
                     ELLGRVRAADLAAHDNADLPFEDAVDAAAPARVAGRNPLFQVMVAQQIRPADTGGLFGL
                     RTRLDDRVIDSAKFDLEFAFIERPGEDGLDGVIRYAAALFDPETVQALAERFTRVLTAV
                     LADPARPVGTADVLLPAERRALDAERGAAAHPVPPRTLPELLAAAPGTREAGPALLFGG
                     ESVSRAEFDGRVARLARELVARGAGPESVVAVALPRSVELVVALHAVVQAGAAYLPLDT
                     DLPAGRLAYMLRTAAPLLVLSDTATARSLPDGDGPETVLLDDPRVQGRLEVRSADPVSD
                     ADRRGRLLAEHPAYVIFTSGSTGRPKGVAVP"
     aSDomain        3989..4876
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_5_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="3.80E-97"
                     /label="ctg4_5_Condensation_Starter.1"
                     /locus_tag="ctg4_5"
                     /protein_end="303"
                     /protein_start="7"
                     /score="317.1"
                     /tool="antismash"
                     /translation="RFDLTGAQSGVWYAQQVDPSGAVYNVGQYVDLVGDLDTGLLQEAL
                     AAVVAETDALRTRIVDDGGVPRQEVLPPGAAGVGRPADAVDLRGEADPEAAALELMLAD
                     MDTPVDLAGGPLHRFALIRTADRRHLWYQRYHHILADAYAISVITRRAAEVYTALAEGA
                     DPGRRFGALADVVAEEEAYEASERREEDGGHWARALADRPEPALLSDAPPATPRRAVRP
                     GARLDAAALSGLEELAGQAGANWAEALIALFGCYVHRRTGAPEAVLGVPAMGRLGSAAL
                     RTPAMVVNVLPLRVP"
     aSModule        3989..7141
                     /complete
                     /domains="nrpspksdomains_ctg4_5_Condensation_Starter.1"
                     /domains="nrpspksdomains_ctg4_5_AMP-binding.1"
                     /domains="nrpspksdomains_ctg4_5_PCP.1"
                     /locus_tags="ctg4_5"
                     /monomer_pairings="Gly -> Gly"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3995..4033
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0001"
                     /evalue="2.80E-02"
                     /label="C1_starter_004-017"
                     /locus_tag="ctg4_5"
                     /protein_end="22"
                     /protein_start="9"
                     /score="7.7"
                     /tool="antismash"
                     /translation="DLTGAQSGVWYAQ"
     CDS_motif       4052..4171
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0002"
                     /evalue="3.40E-17"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg4_5"
                     /protein_end="68"
                     /protein_start="28"
                     /score="54.9"
                     /tool="antismash"
                     /translation="AVYNVGQYVDLVGDLDTGLLQEALAAVVAETDALRTRIVD"
     CDS_motif       4391..4456
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0003"
                     /evalue="8.30E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg4_5"
                     /protein_end="163"
                     /protein_start="141"
                     /score="21.9"
                     /tool="antismash"
                     /translation="YHHILADAYAISVITRRAAEVY"
     CDS_motif       4748..4870
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0004"
                     /evalue="6.90E-12"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg4_5"
                     /protein_end="301"
                     /protein_start="260"
                     /score="37.7"
                     /tool="antismash"
                     /translation="GCYVHRRTGAPEAVLGVPAMGRLGSAALRTPAMVVNVLPLR"
     CDS_motif       4922..5032
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0005"
                     /evalue="6.20E-17"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ctg4_5"
                     /protein_end="355"
                     /protein_start="318"
                     /score="54.0"
                     /tool="antismash"
                     /translation="DALRALRAHQRYRAEDIRRDLSLVGRATGLYGPMVNI"
     aSDomain        5405..6595
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_5_AMP-binding.1"
                     /evalue="9.70E-104"
                     /label="ctg4_5_AMP-binding.1"
                     /locus_tag="ctg4_5"
                     /protein_end="876"
                     /protein_start="479"
                     /score="339.0"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="AAARRAPGAPALRTAESRLDYAGLVRRADAVAARLAAAGAARETV
                     VAIALPRGADLVAALLAASRLGSTYLPIDPDFPADRIAYMLADSGARLLVTTPELDKEL
                     PEGPERVLLGPAGPEQADPAPGTADRATTAPAAAARRHGAAYVLYTSGSTGRPKGVVVP
                     ERGLLNFLRDMGERFPLGADDRWLAVTTVGFDISALELYLPLMHGAELVLADRDTVRDP
                     AALADLAERAGATVMQATPALWRALADERPAVLDRLRVLVGGEALPTDLAERLAARAPS
                     VTNLYGPTETTIWSTASRVRPGEPVDIGAPIANTGAYVLDSALRPVPVGVPGDLYISGE
                     GLARGYAGRPDLTAERFVACPFGAPGERMYRTGDVVRRRADGALEYLGRGDHQVKVR"
     CDS_motif       5585..5626
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0006"
                     /evalue="5.80E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg4_5"
                     /protein_end="553"
                     /protein_start="539"
                     /score="1.4"
                     /tool="antismash"
                     /translation="LAASRLGSTYLPID"
     CDS_motif       5837..5893
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0007"
                     /evalue="2.90E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_5"
                     /protein_end="642"
                     /protein_start="623"
                     /score="28.9"
                     /tool="antismash"
                     /translation="AYVLYTSGSTGRPKGVVVP"
     CDS_motif       6260..6283
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0008"
                     /evalue="9.50E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg4_5"
                     /protein_end="772"
                     /protein_start="764"
                     /score="6.0"
                     /tool="antismash"
                     /translation="YGPTETTI"
     CDS_motif       6386..6475
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0009"
                     /evalue="1.60E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_5"
                     /protein_end="836"
                     /protein_start="806"
                     /score="49.2"
                     /tool="antismash"
                     /translation="PVGVPGDLYISGEGLARGYAGRPDLTAERF"
     CDS_motif       6560..6625
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0010"
                     /evalue="1.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg4_5"
                     /protein_end="886"
                     /protein_start="864"
                     /score="36.1"
                     /tool="antismash"
                     /translation="YLGRGDHQVKVRGFRIELGEVE"
     CDS_motif       6662..6712
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0011"
                     /evalue="1.30E+00"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg4_5"
                     /protein_end="915"
                     /protein_start="898"
                     /score="1.7"
                     /tool="antismash"
                     /translation="VVTAREDVPGQAHLVGY"
     aSDomain        6935..7141
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_5_PCP.1"
                     /evalue="1.40E-22"
                     /label="ctg4_5_PCP.1"
                     /locus_tag="ctg4_5"
                     /protein_end="1058"
                     /protein_start="989"
                     /score="71.6"
                     /tool="antismash"
                     /translation="EERICAVLGEVLGSAPIGVHQDFFALGGHSLLATRAANRIRAELG
                     LHARVRDLFDAPEPARLAALLQER"
     aSDomain        7190..8098
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_5_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.10E-102"
                     /label="ctg4_5_Condensation_LCL.1"
                     /locus_tag="ctg4_5"
                     /protein_end="1377"
                     /protein_start="1074"
                     /score="333.5"
                     /tool="antismash"
                     /translation="DDAPLSYAQERIWFHEELHGPGPAYNVPLAFRLRGPVDAAALALA
                     LRDTVARHDVLRTVHADDGEGPRPRVLPMGRVPELLRTEDAGADPARLDRAVAEVLHTP
                     FDVRTDVPVRAALIRTAPDDAVLALCFHHIATDEWSETPFVRDLDTAYTARTAGEEPRW
                     ERPAVRYTDFARWQRSWLGDAADPGSPMGRGLAYWRRALDGLPAETALPADRPRPAVAD
                     GAGATVRFDLDADTAAALRRAAAAHGTTVFMVLQAAVAVLLHRMGAGDDIPVGTPVTNR
                     DDTAVHDAVGMFLNMLTLRTDL"
     aSModule        7190..10504
                     /complete
                     /domains="nrpspksdomains_ctg4_5_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg4_5_AMP-binding.2"
                     /domains="nrpspksdomains_ctg4_5_PCP.2"
                     /locus_tags="ctg4_5"
                     /monomer_pairings="Gly -> Gly"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7199..7234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0012"
                     /evalue="4.60E-02"
                     /label="C1_starter_004-017"
                     /locus_tag="ctg4_5"
                     /protein_end="1089"
                     /protein_start="1077"
                     /score="7.0"
                     /tool="antismash"
                     /translation="PLSYAQERIWFH"
     CDS_motif       7256..7366
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0013"
                     /evalue="4.20E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg4_5"
                     /protein_end="1133"
                     /protein_start="1096"
                     /score="54.5"
                     /tool="antismash"
                     /translation="PAYNVPLAFRLRGPVDAAALALALRDTVARHDVLRTV"
     CDS_motif       7580..7645
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0014"
                     /evalue="1.60E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg4_5"
                     /protein_end="1226"
                     /protein_start="1204"
                     /score="20.7"
                     /tool="antismash"
                     /translation="FHHIATDEWSETPFVRDLDTAY"
     CDS_motif       7697..7732
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0015"
                     /evalue="8.40E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg4_5"
                     /protein_end="1255"
                     /protein_start="1243"
                     /score="15.2"
                     /tool="antismash"
                     /translation="YTDFARWQRSWL"
     CDS_motif       8000..8089
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0016"
                     /evalue="7.20E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg4_5"
                     /protein_end="1374"
                     /protein_start="1344"
                     /score="34.5"
                     /tool="antismash"
                     /translation="DIPVGTPVTNRDDTAVHDAVGMFLNMLTLR"
     CDS_motif       8138..8257
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0017"
                     /evalue="7.60E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg4_5"
                     /protein_end="1430"
                     /protein_start="1390"
                     /score="47.2"
                     /tool="antismash"
                     /translation="READIEAFAHAGVPFEAVVRETDPSRSAARHPLFQVMLTY"
     aSDomain        8597..9781
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_5_AMP-binding.2"
                     /evalue="2.00E-107"
                     /label="ctg4_5_AMP-binding.2"
                     /locus_tag="ctg4_5"
                     /protein_end="1938"
                     /protein_start="1543"
                     /score="351.1"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="ARTAAEHPDRTAVRAGSERVGYAELARRADAVAARLAAAGAVRES
                     VVAVALPRGADLVAALLAVGRTGAAYLPIDPDFPADRIAYMLADSGARLLVTTPELDPV
                     LPAGPARLLLGPDAPGGAAASQAAGAVLSFLDPHPDSAAYVLYTSGSTGRPKGVVVPHR
                     ALLNFLLDMAERFPLDAGDRWLAVTTVGFDISALELYLPLMQGAELVLADRDTVRDPAA
                     LADLAEESGATVMQATPALWRALAEDRPEALDGLRALVGGEALPRDLAERMAARTAHTA
                     NLYGPTETTIWSTVSRVRVGEPVDIGAPIANTGVYVLDASLRPVPVGVPGDLYISGEGL
                     ARGYAGRPDLSAERFVACPFGAPGERMYRTGDVVRWRADGALEYLGRGDHQVKVR"
     CDS_motif       8780..8821
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0018"
                     /evalue="1.50E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg4_5"
                     /protein_end="1618"
                     /protein_start="1604"
                     /score="9.2"
                     /tool="antismash"
                     /translation="LAVGRTGAAYLPID"
     CDS_motif       9023..9082
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0019"
                     /evalue="3.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_5"
                     /protein_end="1705"
                     /protein_start="1685"
                     /score="31.9"
                     /tool="antismash"
                     /translation="AYVLYTSGSTGRPKGVVVPH"
     CDS_motif       9446..9469
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0020"
                     /evalue="9.50E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg4_5"
                     /protein_end="1834"
                     /protein_start="1826"
                     /score="6.0"
                     /tool="antismash"
                     /translation="YGPTETTI"
     CDS_motif       9572..9661
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0021"
                     /evalue="1.60E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_5"
                     /protein_end="1898"
                     /protein_start="1868"
                     /score="46.0"
                     /tool="antismash"
                     /translation="PVGVPGDLYISGEGLARGYAGRPDLSAERF"
     CDS_motif       9746..9811
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0022"
                     /evalue="1.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg4_5"
                     /protein_end="1948"
                     /protein_start="1926"
                     /score="36.1"
                     /tool="antismash"
                     /translation="YLGRGDHQVKVRGFRIELGEVE"
     CDS_motif       9848..9904
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0023"
                     /evalue="6.70E+00"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg4_5"
                     /protein_end="1979"
                     /protein_start="1960"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="VVTAREDVPGQAYLVGYLV"
     aSDomain        10304..10504
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_5_PCP.2"
                     /evalue="3.00E-25"
                     /label="ctg4_5_PCP.2"
                     /locus_tag="ctg4_5"
                     /protein_end="2179"
                     /protein_start="2112"
                     /score="80.1"
                     /tool="antismash"
                     /translation="EREMCAIAAEVLGLPSLGVHDDFFTSGGHSLAAARTVNRMRARLG
                     LDIGVRDLFEAPTVAGLAARTA"
     aSDomain        10580..11515
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_5_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.90E-98"
                     /label="ctg4_5_Condensation_LCL.2"
                     /locus_tag="ctg4_5"
                     /protein_end="2516"
                     /protein_start="2204"
                     /score="321.0"
                     /tool="antismash"
                     /translation="APAPLSAEQRRLWLLDGMNPGSDAYNVPWALRISGPLDRAALAAA
                     ARDVLLRHEVLRTRFPLPEGAAEPVQQVVPEDALPADPLRVEEPRTAAPQDGAAGADHR
                     VEAAARAPFDLGSDLPVRFTLFPEGEDEHLLLVVFHHIAVDEWSQAPFLRDLDTAYLAR
                     LDGRAPDQAPIPVQYADYAAWQAELLGDGDDPGSAAARQRAFWAEALAGLPEETALPAD
                     RPRPAGGMPADGGVVGFRVPPALRKAAEELAESTGTTRFMVLRTAVAVLLHRMGAGDDV
                     ALGAPAANRTDEALHDLVGMFLNTLVLRTDL"
     CDS_motif       10589..10621
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0024"
                     /evalue="4.70E-01"
                     /label="C1_starter_004-017"
                     /locus_tag="ctg4_5"
                     /protein_end="2218"
                     /protein_start="2207"
                     /score="4.1"
                     /tool="antismash"
                     /translation="PLSAEQRRLWL"
     CDS_motif       10646..10762
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0025"
                     /evalue="3.50E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg4_5"
                     /protein_end="2265"
                     /protein_start="2226"
                     /score="54.8"
                     /tool="antismash"
                     /translation="DAYNVPWALRISGPLDRAALAAAARDVLLRHEVLRTRFP"
     CDS_motif       10994..11059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0026"
                     /evalue="4.20E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg4_5"
                     /protein_end="2364"
                     /protein_start="2342"
                     /score="22.6"
                     /tool="antismash"
                     /translation="FHHIAVDEWSQAPFLRDLDTAY"
     CDS_motif       11108..11146
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0027"
                     /evalue="1.50E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg4_5"
                     /protein_end="2393"
                     /protein_start="2380"
                     /score="14.4"
                     /tool="antismash"
                     /translation="QYADYAAWQAELL"
     CDS_motif       11417..11506
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0028"
                     /evalue="1.10E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg4_5"
                     /protein_end="2513"
                     /protein_start="2483"
                     /score="40.3"
                     /tool="antismash"
                     /translation="DVALGAPAANRTDEALHDLVGMFLNTLVLR"
     CDS_motif       11555..11671
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0029"
                     /evalue="1.70E-13"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg4_5"
                     /protein_end="2568"
                     /protein_start="2529"
                     /score="42.8"
                     /tool="antismash"
                     /translation="RAADLAAHDNADLPFEDAVDAAAPARVAGRNPLFQVMVA"
     CDS_motif       12203..12241
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0030"
                     /evalue="2.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg4_5"
                     /protein_end="2758"
                     /protein_start="2745"
                     /score="11.5"
                     /tool="antismash"
                     /translation="AVVQAGAAYLPLD"
     CDS_motif       12458..12511
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_5_0031"
                     /evalue="6.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_5"
                     /protein_end="2848"
                     /protein_start="2830"
                     /score="27.9"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGRPKGVAV"
ORIGIN
        1 ctgcaccggc ggctcggcat cggccccggc gacccggtgg tggtgcagct gccgaacgtc
       61 cccgaggtgt tcgaggtggt cttcgccctg ttccggctgg gcgccctgcc ggtgtacgcg
      121 ctgcccgcgc accgctccgc cgagatcggc cacctgcacg cggtgaccgg ggcgcgggcg
      181 ctggtcgtct ccgccgcccg cggccccttc gaccacgtcc ggatggcccg cgagatcgcc
      241 gccggaaccg gggacggccc cgccccgcac gtgatcgggg tcggcgccgc cgaccccgga
      301 gcgctcaccg aagcaggcgc ggtcccgctg gaaacactgc gcgccgaagc cgccgacccc
      361 gccgcgctct ccgaccccga cccctccgac gtcgcgttct tccagctctc cggcggcacc
      421 accggactgc ccaagctcat cccgcgcacc cacgacgact acctgtactc ggtgcgggcc
      481 agcgccgaca tctgcgggct cacccccgac acggtcttcc tcggcgcgct gcccgtcgtg
      541 cacaacttcc cgatgagctc ccccggcttc ctcggggtga tgcacgccgg cggcagcacc
      601 gtgctggccc ccgaccccag ccccgccacc tgcctggagc tgatcgaacg ggagcgggtc
      661 accctcgccg ccgcggtccc gccggtcgcc atgctctggc tggacgcggt ggacggcggc
      721 gcccaggccc accgcgacct ctcctcgctg cggatgctcc aggtcggcgg cgccaagttc
      781 gcccccgaag cggccaagcg cgtcgccggc accctcggct gccggctgca acaggtcttc
      841 ggcatggccg aagggctggt caactacacc cgggacgagg acgacgaggc gaccgtcacc
      901 ggcacccagg gccggcccat ctcccccggc gacgagctgc gcgtggtcgg cccggacggc
      961 gccgaggtgc cgcccggcga acccggcgaa ctgctcaccc gcggccccta caccatccgc
     1021 ggctactacc gggcgcccga gcacaacgcc agggcgttca ccccggacgg cttctaccgc
     1081 accggcgacg tggtccgggt cgcgcccagc ggccacatca ccgtcgaggg ccgggtcaag
     1141 gaccagatca accggggcgg cgagaagatc gcgccggacg aggtggagga ccacctcctg
     1201 gcgcaccccg gggtgcacga cgccgccgtc gtcgcgatgc ccgaccccta cctcggcgag
     1261 cgcgcctgcg cctacgtcat cccccgggac ggcgccggcg acgggctcga ccgccccgcc
     1321 ctgctccgct tcctgcgcgg ccgcggcctg gccgcctaca agatccccga ccgggtcgag
     1381 gtggtgccgg agttccccgc caccggcgtc ggcaaggtca gcaagcgcga cctgcgggcc
     1441 gccatcgccg acgcggtcac cgccggccgg cactgagaac cggcgaccca gagaggaacc
     1501 gaggaaaccc cgatgtccct gccgcagatc gcaccctacg agccgccggc gccggaccgc
     1561 ctcccggaca accgcgccca gtggcggccc gaacccgagc gcgccgtgct gctcgtgcac
     1621 gacatgcagc gctacttcct gcggccctac gcgcacggcg ccgaaccgct gaaccgggcc
     1681 accgccaaca tcgcccgcct cgccgccgcc tgccgggccg ccggcgtccc ggtggtctac
     1741 accgccaagc ccggcgacat gccgcgcgag cggcgcggcc tggagatcga cttctggggc
     1801 agcgggatgc gcgccgtccc cgagcacacc accatcgacg acgcggtccg ccccgaaccc
     1861 ggcgacaccc tcctcaccaa gtggcgctac agcgccttcg cccagaccga cctggagcag
     1921 cgcctcgccg ccatgggccg cgaccagctg ctcgtcaccg gggtctacgc ccacatcggc
     1981 tgcctgctca ccgccgccga cgccttcatg cgcgacatcc agccgttctt cgtcgccgac
     2041 gcgatggccg acttcaccgc cgaggaccac cacttcgcgg tccgctacgt cgcccggcgc
     2101 tgcggcgtcg cactgaccac cgacgccgcc ctggacggcg tccgcgccac cgaccgcagc
     2161 accgccgcgg ccggctgacc acggccggcg accaccgcga ccgcccctct cgaaaggacc
     2221 actgtgacca ccacccggac cacggacgcc ccgccggtgc acgacctcgc cggcatcgga
     2281 ttcggcccgt ccaacgtcgc cctcgcgatc gcgctgcgcg agcggcgcga gcaggccgcc
     2341 gccgaccccg ggcgcaccgc cccgaccgcg gtgttccacg agcgccagca ggagttcggg
     2401 tggcaccgcg ggatgctcct ggacgacgcc accatgcagg tgtccttcct caaggacctg
     2461 gtcaccaccc gcaacccggc cagcgacttc tccttcctca gctacctgca ccaggccggg
     2521 cggctgcacg acttcatcaa ccacaagacg ctgttcccgc tccgctcgga gttccacgac
     2581 tacctggcct ggtgcgcggg gcggctgtcc gactcggtcc gctacggctc cgaggtgatc
     2641 ggcgtggagc cggtgcgcga cgccgccggc cggatctccg cggtggacgt gctggcccgg
     2701 gaggccggcc ccggcggaga gcgcacccac cgcacccggg cccgcaacct ggtcatcgcc
     2761 cccggcctct ccccgcggct gcccgagggc gtccggctcg gcgagcgcgt ctggcacaac
     2821 gagtacctgc tgcaccggct ggaggcgctg ggcgagggcg ccgccccccg ctcgttcgcc
     2881 gtcgtcggcg cagggcagag cgccgccgag gtcgccgacc acctctaccg ccgcttcccc
     2941 ggcgccgagg tgaacgcggt gttctcccgg tacggctaca gcccctccga cgacagccag
     3001 ttcgccaacc ggatcttcga ccccgaggcc gtcgacgcct tctacgacgc ctcggacgag
     3061 accaaggccc agatcatggg ctaccacggc aacaccaact actcggtggt cgaccccgac
     3121 ctgatcgaga gcatgtaccg tgccgtctac caggaccggg tgctgggcac cgagcggctg
     3181 cacatgcaca agctgtcccg cgtcaccggg gtcgaggagg acgccgacgg cgtcaccctc
     3241 accgtcgagc acctcccctc cggcaagcag cggccgctcc gcgcggacta cgtcgtctac
     3301 gccaccggct accaccccgc cgccccgctc tccctgctcg gcgggctcgc cgagcacgtg
     3361 gcgaccgacg cccgcggccg gcacgccgtc ggccgcgact accggctgat caccgacgac
     3421 gaggtcacct gcgggatcta cctgcagggc ggcaccgagc acacgcacgg catctcctcg
     3481 tcgctgctgt ccaacgtcgc cgtccgcgcc ggggagatcc tcgactccgt cggggcgcgc
     3541 accgccggcg ccgcggcggc ctgaacggcg ccccgaccgc ggcacccgcc cccaccggcc
     3601 cgcccctacg cccacttcta cgaaagggca gcacggagat gaccgacacc gcgctcaccc
     3661 ccgagcggat ccgcgccgac gtggagaggg tcctcggcga gcagccgggc accgtccccg
     3721 gcacggagaa cctcctcgac ctcggcatgg actcgatccg cctgatgagc ctggtggagt
     3781 cctggcgcac cgccggcgcg cagaccgact tcatcgagct cgccgaggaa cccagcatcg
     3841 acgcctggac ccgcctgctc gccggcggct gatcacacca ccccggcgga aaccctccgg
     3901 ggcgccgacc cctgcccgcc gcaccgcccg ccaccgcagc cactctcccg acccggagcc
     3961 accgaagatg accgacaccc ctcacccccg gttcgacctc accggagccc agagcggggt
     4021 ctggtacgcc cagcaggtcg acccttccgg agccgtctac aacgtcggcc agtacgtcga
     4081 cctcgtcggc gacctggaca ccggactgct ccaggaggcg ctggccgccg tggtcgccga
     4141 gaccgacgcg ctgcgcaccc gcatcgtcga cgacggcggg gtgccccgac aggaggtgct
     4201 cccgcccggc gccgcgggcg tcgggcggcc cgcggacgcg gtcgacctgc gcggcgaggc
     4261 cgacccggag gcggccgcgc tggagctgat gctggccgac atggacaccc cggtggacct
     4321 ggccggcggg ccgctgcacc ggttcgcgct gatccgcacc gccgaccggc ggcacctgtg
     4381 gtaccagcgc taccaccaca tcctcgccga cgcctacgcg atcagcgtga tcacccgccg
     4441 ggcggccgag gtctacaccg ccctcgccga gggggccgac cccggccgcc ggttcggcgc
     4501 gctggccgac gtcgtcgccg aggaggaggc ctacgaggcc tccgagcggc gggaggagga
     4561 cggcggccac tgggcccggg ccctggccga ccgccccgaa cccgccctgc tctcggacgc
     4621 accgcccgcg accccccggc gggcggtgcg ccccggggcg cggctggacg cggcggccct
     4681 gtccggcctg gaggaactgg ccggacaggc cggcgccaac tgggcggagg cgctgatcgc
     4741 cctgttcggc tgctacgtgc accgccgcac cggcgccccc gaggcggtgc tcggcgtgcc
     4801 ggcgatgggc cggctcggct cggcggcgct gcgcaccccc gccatggtgg tgaacgtgct
     4861 gccgctgcgg gtccccgccg cccccggcga caccgtcgcc gaggcggtcc ggcgcacccg
     4921 ggacgcgctg cgcgcactcc gcgcgcacca gcgctaccgg gccgaggaca tccgccgcga
     4981 cctcagcctg gtcggccgcg ccaccggcct gtacgggccg atggtcaaca tcaaggcctt
     5041 cgactacgac gtccgcttcg gggaggtccg cggcgacacc cggaccctct ccgaggggcc
     5101 cgtcgacgac gtctcgctgt cggtcgccgc cgacagcggc gccggcggcc tgcacctcgt
     5161 gctcaacgcc aacccggagc gctacaccga gcaggaggcc gccgaccgcc tcgccgagtt
     5221 cgtccggatg gtcgaagggc tgctctcccg cccggaaccg ggcaccgggg agggcggagc
     5281 cggcgccgcg gcctccgccc gggtcgcctc gctcgacctg gtcggcgccg ccgagcgcgc
     5341 cctgctcacc gcgccccccg aaccccgccc ggtgcccgag gactccgtcg ccgaccaggt
     5401 cgccgcagcg gcccggcgcg cccccggcgc ccccgcgctg cgcaccgccg agagcaggct
     5461 ggactacgcc gggctggtcc gccgcgccga cgcggtcgcc gcccggctgg ccgccgccgg
     5521 cgcggcccgg gagacggtcg tcgcgatcgc cctgccgcgc ggcgccgacc tggtcgccgc
     5581 gctgctcgcg gcgagccggc tgggcagcac ctacctgccg atcgacccgg acttcccggc
     5641 cgaccggatc gcctacatgc tcgccgactc cggcgcccgc ctcctggtca ccacccccga
     5701 gctggacaag gagctgcccg agggcccgga gcgggtgctg ctcggccccg ccggcccgga
     5761 gcaggccgac cccgcgcccg gcaccgccga ccgggcgacc acggcccccg ccgcggcggc
     5821 ccgccggcac ggcgccgcct acgtgctcta cacctccggt tccaccggcc gccccaaggg
     5881 agtggtggtc cccgagcggg gcctgctcaa cttcctgcgg gacatggggg agcggttccc
     5941 gctcggcgcg gacgaccggt ggctcgcggt gaccaccgtg ggcttcgaca tctccgccct
     6001 ggagctgtac ctgccgctga tgcacggcgc cgaactggtg ctggccgacc gggacaccgt
     6061 gcgcgacccc gccgccctcg ccgacctggc cgaacgggcc ggcgccacgg tcatgcaggc
     6121 cacccccgcc ctctggcgcg ccctggccga cgagcgcccg gcggtgctcg accggctccg
     6181 ggtcctcgtc ggcggggaag cgctccccac cgacctggcc gagcggctcg ccgcccgcgc
     6241 cccctcggtc accaacctgt acggccccac cgagaccacc atctggtcca ccgcctcccg
     6301 ggtccgcccc ggcgaaccgg tggacatcgg cgccccgatc gccaacaccg gggcctacgt
     6361 cctcgactcc gccctgcgcc cggtcccggt cggcgtcccc ggcgacctgt acatctccgg
     6421 cgaagggctg gcccgcggct acgccggccg cccggacctg accgcggagc ggttcgtcgc
     6481 ctgcccgttc ggcgcccccg gggagcggat gtaccgcacc ggcgacgtgg tgcgccgccg
     6541 cgccgacggc gccctggagt acctgggccg cggcgaccac caggtcaagg tgcgcggctt
     6601 ccggatcgag ctcggcgagg tcgaggtccg gctcggccgg ctgcccggcg tcgcccaggc
     6661 cgtggtcacc gcccgcgagg acgtccccgg ccaggcccac ctggtcggct atgcggtgtt
     6721 cgaggacggc gccgacaccg acccggcccg gctccgcgcg gcgctggccg aaacgctgcc
     6781 cgactacatg gtcccctcgg cgttcgtcgc cctggacgcg ttcccgctga ccgagaaccg
     6841 caagatcgac cgcaaggcgc tgcccgcccc cgcaggcgcc ggtgccgccg ccggggaccg
     6901 ccccgccccg gacgccgcgc cgcgcacccc cgtcgaggag cggatctgcg ccgtcctcgg
     6961 cgaagtgctc ggcagcgccc cgatcggggt gcaccaggac ttcttcgcgc tcggcggcca
     7021 ctcgctgctc gccacccgcg ccgccaaccg gatccgcgcc gagctcggcc tgcacgcccg
     7081 ggtccgcgac ctgttcgacg cccccgaacc ggcccgcctc gccgccctgc tccaggagcg
     7141 ctccggcggc gacgaccgcc cgccgctcac cgcccacccc ggccccgacg acgacgcccc
     7201 gctctcctac gcccaggagc gcatctggtt ccacgaggag ctgcacggcc ccggaccggc
     7261 ctacaacgtc ccgctcgcct tccggctgcg cggccccgtc gacgccgccg ccctcgccct
     7321 ggcgctccgc gacaccgtcg cccggcacga cgtgctgcgc acggtccacg ccgacgacgg
     7381 ggaggggccg cggccgcgcg tgctgcccat gggccgggtc cccgaactgc tccgcaccga
     7441 ggacgccggc gccgacccgg cccggctcga ccgggccgtc gccgaggtgc tgcacacccc
     7501 cttcgacgtg cgcaccgacg tcccggtgcg ggccgcgctg atccgcaccg cgcccgacga
     7561 cgcggtgctg gcgctctgct tccaccacat cgccaccgac gagtggtcgg agacgccgtt
     7621 cgtccgcgac ctggacaccg cctacaccgc ccgcaccgcc ggcgaggagc cccgctggga
     7681 gcggcccgcg gtccgctaca ccgacttcgc ccgctggcag cggtcctggc tcggcgacgc
     7741 cgccgacccc gggtcgccga tggggcgcgg gctcgcctac tggcggcgcg cgctggacgg
     7801 gctgcccgcc gagaccgccc tgcccgcgga ccggccgcgg cccgccgtcg ccgacggtgc
     7861 cggcgcgacc gtccgcttcg acctggacgc cgacaccgcc gccgcactgc gccgcgccgc
     7921 cgccgcgcac ggcaccaccg tcttcatggt cctccaggcc gccgtcgcgg tgctgctgca
     7981 ccggatgggc gccggcgacg acatccccgt cggcaccccg gtcaccaacc gggacgacac
     8041 cgccgtgcac gacgcggtcg gcatgttcct gaacatgctc accctgcgca ccgacctgtc
     8101 cggggcgccc accggccggg agctgctggc gcggatccgc gaggccgaca tcgaggcgtt
     8161 cgcgcacgcc ggcgtcccgt tcgaggcggt ggtgcgggag accgacccgt cccgctccgc
     8221 cgcacgccac ccgctcttcc aggtcatgct gacctaccag cgcgaacccg accaccccgg
     8281 gctgctcggc accgactcct cggtgcaccc gatcgacatc gccacctcca agctcgacct
     8341 ggagttcacc ttcgccgagt tccccggcgg cggagggctg gccgcgaacc tgcgctacgc
     8401 caccgcccgc ttcgaccggg ccaccgccga gggcctggcg gagcggttcc gccaagtgct
     8461 gatcgccctg ctggtcgcgc cggacgtccc ggtcggcgaa cacgaggtgc tcaccgacgc
     8521 cgagcgcagc gccctgctgc gcggcgccgg ggccaccgcc cgcccggtcc ccgccccggg
     8581 gctggcccgg cgcatcgccc gcaccgccgc cgagcacccg gaccgcaccg ccgtgcgcgc
     8641 cgggagcgag cgggtcggct acgccgagct ggcccgccgc gccgacgcgg tcgccgcccg
     8701 gctggccgcc gccggcgcgg tccgcgaatc ggtggtggcg gtggcgctgc cgcgcggcgc
     8761 cgacctggtc gccgcactgc tcgcggtcgg ccgcaccggc gccgcctacc tgccgatcga
     8821 cccggacttc ccggccgacc ggatcgccta catgctcgcc gactccggtg cccgcctcct
     8881 ggtcaccacc cccgaactcg acccggtgct gccggccggc ccggcccggc tgctgctcgg
     8941 cccggacgcc cccggcggcg cggccgcgtc ccaggcggcc ggcgcggtgc tctccttcct
     9001 ggacccgcac cccgactccg ccgcctacgt gctctacacc tccggctcca ccggccgccc
     9061 caagggcgtg gtggtcccgc accgcgcgct gctcaacttc ctgctggaca tggcggagcg
     9121 gttcccgctg gacgccggcg accggtggct cgcggtgacc accgtgggct tcgacatctc
     9181 cgccctggag ctgtacctgc cgctgatgca gggggcggag ctggtgctgg ccgaccggga
     9241 caccgtgcgc gaccccgccg ccctcgccga cctggccgag gagagcgggg cgacggtcat
     9301 gcaggccacc cccgccctct ggcgcgccct ggccgaggac cggccggagg ccctggacgg
     9361 cctgcgcgcc ctggtcggcg gcgaggcgct cccgcgcgac ctggcggagc ggatggcggc
     9421 gcgcaccgcg cacaccgcca acctgtacgg gccgaccgag accaccatct ggtccacggt
     9481 ctcccgggtg cgcgtcggcg agccggtgga catcggcgcc ccgatcgcca acaccggggt
     9541 gtacgtgctg gacgcgtcgc tgcgcccggt cccggtcggc gtccccggcg acctgtacat
     9601 ctccggcgaa gggctggccc gcggctacgc cggccgcccg gacctgtccg cggagcggtt
     9661 cgtggcgtgc ccgttcggtg cgccggggga gcggatgtac cgcaccggcg acgtggtgcg
     9721 gtggcgcgcc gacggtgccc tggagtacct gggccgcggc gaccaccagg tcaaggtgcg
     9781 cggcttccgg atcgaactcg gcgaggtcga ggaggcgctg tcccgggccg aaggcgtcgg
     9841 ccaggcggtg gtgaccgccc gcgaggacgt ccccggccag gcctacctgg tcggctacct
     9901 ggtccccgag cccggaggcg cggaccccga cccggcccgg ctccgcgcgg cgctggccga
     9961 aacgctgccc gactacatgg tcccctcggc gttcgtcgcc ttggacgcgt tcccgctgac
    10021 cgagaaccgc aagatcgacc gcaagtccct cccgtcgccc gccgtttccg gtgcggagcc
    10081 ttcggggccc cgctcgtcgt ccgccgcctc cgccgaaggc ccttcaggcg gcggtggttc
    10141 cctgcgtgcc ggcaccggtc ccggccgagg cgctccggaa gagggacggc cctcctcttc
    10201 agggccgctc cgcgcccggc tgctgctcgc ccccggcgca gacggtgcgg ccgggaccac
    10261 cgagtccgcc agggccgcgg gcggcgagcc ccgggacgag accgagcggg agatgtgcgc
    10321 gatcgccgcc gaggtcctcg gcctgccctc gctcggcgtg cacgacgact tcttcaccag
    10381 cggcgggcac tcgctcgccg ccgcgcggac ggtcaaccgg atgcgcgccc gcctcggcct
    10441 ggacatcggc gtccgcgacc tgttcgaggc gcccaccgtc gccgggctcg cggcccgcac
    10501 cgccgcgcgc tccgccgcct ccggcgggga ccggcccgcg gccgcccgcc cgcccctggc
    10561 ccgccgcacc gacccggacg cccccgcgcc gctctccgcc gaacagcgcc ggctgtggct
    10621 gctggacggg atgaacccgg gctccgacgc ctacaacgtc ccctgggcac tgcggatctc
    10681 cggccccctg gaccgcgcgg ccctggccgc cgccgcccgc gacgtgctgc tccggcacga
    10741 ggtgctgcgc accaggttcc cgctgcccga gggcgccgcc gaaccggtcc agcaggtggt
    10801 cccggaggac gccctccccg ccgatccgct ccgcgtcgag gagccgcgca ccgccgcccc
    10861 gcaggacggg gcggccgggg cggaccaccg ggtcgaggcg gccgcgcggg ccccgttcga
    10921 cctcggctcc gacctgccgg tccggttcac cctcttcccc gagggcgagg acgagcacct
    10981 gctgctggtc gtcttccacc acatcgcggt ggacgagtgg tcccaggcgc ccttcctgcg
    11041 cgacctggac accgcctacc tggcccgcct ggacgggcgg gccccggacc aggcgccgat
    11101 cccggtccag tacgccgact acgccgcctg gcaggccgaa ctgctcggcg acggggacga
    11161 cccgggcagc gcggccgccc ggcagcgggc gttctgggcc gaggcgctgg ccggcctccc
    11221 cgaggagacg gcgctccccg ccgaccggcc ccggccggcc ggcggaatgc cggccgacgg
    11281 cggcgtggtc gggttccggg tgccgcccgc gctccgcaag gccgccgagg agctggccga
    11341 gtccaccggc accacccgct tcatggtgct gcgcaccgcc gtcgccgtgc tgctgcaccg
    11401 gatgggcgcc ggcgacgacg tcgcactggg ggcgcccgcc gccaaccgca ccgacgaggc
    11461 gctgcacgac ctggtcggca tgttcctcaa cacgctggtg ctccgcaccg acctgtccgg
    11521 cgaccccggc ttcacggaac tgctgggccg ggtgcgcgcc gccgacctcg ccgcgcacga
    11581 caacgccgac ctgccgttcg aggacgccgt ggacgccgcg gccccggccc gggtcgccgg
    11641 ccgcaacccg ctgttccagg tgatggtggc gcagcagatc cgccccgccg acaccggcgg
    11701 cctcttcggg ctccgcaccc gcctggacga ccgggtcatc gacagcgcca agttcgacct
    11761 ggagttcgcc ttcatcgaac gccccggcga ggacgggctg gacggcgtga tccgctacgc
    11821 cgcggccctg ttcgacccgg agaccgtgca ggcgctggcc gagcggttca cccgggtgct
    11881 caccgccgtc ctggccgacc cggcgcgccc cgtgggcacc gccgacgtgc tgctgccggc
    11941 cgaacggcgc gccctggacg ccgagcgcgg cgccgccgcg caccccgtcc cgccgcggac
    12001 gctgcccgag ctgctggccg cggcccccgg tacccgggag gcagggcccg ccctgctctt
    12061 cgggggcgag tccgtctccc gtgcggagtt cgatgggcgg gtggcgcggt tggcgcgtga
    12121 gctggtggcg cgaggtgcgg gtccggagtc ggtggtggcg gtggcgttgc cgcgttcggt
    12181 ggagctggtg gtggctctgc atgcggttgt gcaggcgggg gcggcgtatc tgccgctcga
    12241 caccgacctg cccgccggcc ggctggccta catgctccgc accgcggcgc cgctgctggt
    12301 gctctccgac accgcgacgg cacggtcgct gccggacggg gacggaccgg agaccgtgct
    12361 gctggacgac ccgcgcgtcc agggccgcct ggaggtccgc tccgccgatc cggtgtcgga
    12421 tgcggatcgg cgggggcggc tgcttgcgga gcaccctgcg tatgtgatct tcacgtcggg
    12481 ttcgacgggg cgtccgaagg gtgtggcggt gccg
//
