LOCUS       BGC0002019             24752 bp    DNA     linear   BCT 15-MAR-2019
DEFINITION  TPA_exp: Streptomyces sp. CB03234, complete sequence.
ACCESSION   BGC0002019
VERSION     BGC0002019
KEYWORDS    .
SOURCE      Streptomyces sp. CB03234
  ORGANISM  Streptomyces sp. CB03234
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     THIRD PARTY DATABASE: This TPA record uses data from
            DDBJ/EMBL/GenBank entry LIYH01000003.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 16:43:36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 24752
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1296
                     /codon_start=1
                     /gene_functions="transport (smcogs)
                     SMCOG1117:sodium/hydrogen exchanger (Score: 391; E-value:
                     9.3e-119)"
                     /gene_kind="transport"
                     /note="Orf1"
                     /product="Na/H exchanger"
                     /protein_id="DAC74128.1"
                     /transl_table=11
                     /translation="MNAQHLTELFFALAAVVLLARLLGAVARRFDQPAVIGEVLAGVLM
                     GPTLFGGAVSDHLFPAGIRPSLGVLAAVGVAVFMFIVGLEWDPALARGSGGFAVTVSLS
                     SVLLPFGLGAALAVYLMREYDTPDKAAFVLFMGIAMSITAFPVLARILTDRGMERTTLG
                     VLALACASIDDVLAWSVLAGVAALSGAAGPGPARMLLALPYVLGMLFVLRPLLRRVLAH
                     GGTVRLTPAWTACALVGMLASAATTEWVGLHFIFGAFLFGAVIPRERTARLRAGIRDQL
                     GRLSDVLLLPVFFVVAGLNVDLSGLSVGGLGDLGLILLVAIGGKFAGAFLAARAHGMPS
                     RQSAALATLMNTRGLTELIALSVGLNLGIIQQDLYSLMVVMAVVTTAMAGPLLRWLLPR
                     RLIEAEAARESVPADSTDVRPDAPTRTSPPPG"
     source          1..24752
                     /db_xref="taxon:1703937"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. CB03234"
                     /strain="CB003234"
     misc_feature    1..24752
                     /note="tiancilactone biosynthesis gene cluster"
     subregion       1..24752
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="terpene"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..24752
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             1387..1605
                     /codon_start=1
                     /note="TnlR1"
                     /product="LuxR family regulator"
                     /protein_id="DAC74129.1"
                     /transl_table=11
                     /translation="MTRLASEPSLTPRQTEVVRLAVLGLTAKETARRLGISKNTVDEHL
                     REARHRVGAATKSRLIGWAVASGIVPF"
     CDS             complement(1676..2542)
                     /NRPS_PKS="Domain: TauD (10-251). E-value: 4e-63. Score:
                     205.5. Matches aSDomain: nrpspksdomains_DAC74131.1_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121:dioxygenase, TauD/TfdA (Score: 268.4; E-value:
                     1.1e-81)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlO1"
                     /product="alpha-ketoglutarate-dependent dioxygenase"
                     /protein_id="DAC74131.1"
                     /sec_met_domain="TauD (E-value: 1.7e-63, bitscore: 205.5,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESLRTAFDVRPLSGALGAEVLGVRLEDITDEEFAELRRLLLRY
                     LVLFLPEQEGWSSESRIAFGRRFGELEVHPYLPHLDGHPEIQIIDSEQDGKIPIWHTDM
                     TYSPNPPIGSVLQIVRSPGRGGDTMWSNQYLAYESLSAPMRELLDGLTAIHAIHIPGLD
                     SRAEHPVVRVHPETGRRALFVNRAHTSHIVQLSRNESDALLQFLTEFSTSPQFTCRYQW
                     RPGDVAIWDNRVTQHYAVDDYEERRTGLRVVVLGDDPTGNKPRWSPYRPKPGERYAPAR
                     VNAKEPY"
     aSDomain        complement(1790..2512)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DAC74131.1_TauD.1"
                     /evalue="4.00E-63"
                     /label="DAC74131.1_TauD.1"
                     /locus_tag="DAC74131.1"
                     /protein_end="251"
                     /protein_start="10"
                     /score="205.5"
                     /tool="antismash"
                     /translation="VRPLSGALGAEVLGVRLEDITDEEFAELRRLLLRYLVLFLPEQEG
                     WSSESRIAFGRRFGELEVHPYLPHLDGHPEIQIIDSEQDGKIPIWHTDMTYSPNPPIGS
                     VLQIVRSPGRGGDTMWSNQYLAYESLSAPMRELLDGLTAIHAIHIPGLDSRAEHPVVRV
                     HPETGRRALFVNRAHTSHIVQLSRNESDALLQFLTEFSTSPQFTCRYQWRPGDVAIWDN
                     RVTQHYAVDDYEERRTGLR"
     CDS             complement(2568..3830)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 182.8; E-value:
                     2e-55)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlT1"
                     /product="FAD-dependent GGPP epoxidase"
                     /protein_id="DAC74130.1"
                     /transl_table=11
                     /translation="MDADVVVCGAGVAGLAAACALGRLGLDVALLEKNRRQPPVWKGEV
                     LQPGSLNTLHSWGALPALEARGAVRLNRLVTRRADGAELLTMDFGVLGGERPWMLSHDY
                     TTILECLGESLGTTVHWQRGVLVKDVVKDGDGRVVGVRAVRDGSEYDVRARLVVAADGM
                     SSRVRRLSGLSASPVAYGHKLLSFELAGTPDLDDEVSAYVTDRGLVMVYPLPDRRTRVY
                     VQVAPDEIRGADRARLQQWCDELIAGVPALGPLSPAFKEGLDRRQLLPVWQYRAPSLVR
                     PGIALIGEAAHGVHPLAAQGMNTAIGDAQVLADRLAGVDVTGREAVDRALRAYEAGRRD
                     RIRDIHVMSHRAARMMTSTSGLGRALGLRLLTGTARSARLRRLTTYNMSGLGMRPLGTV
                     DRLVQLGVLPDRKVPRLPAPK"
     CDS             complement(3857..5671)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: terpene_cyclase"
                     /gene_kind="biosynthetic"
                     /note="TnlT2"
                     /product="type II diterpene synthase"
                     /protein_id="DAC74132.1"
                     /sec_met_domain="terpene_cyclase (E-value: 2.6e-52,
                     bitscore: 168.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCSAVDGRVEKSVARSVAKAAEALFEVQRPDGSWPNRRPTAVLGT
                     AGALAALHVADRERSNDLIERGAAWLAGAQNADGGWGGVAGASTQLVPTVIAAASLHLV
                     SPHTSREPVQRALDLVKSYGGTEALTDPGMAHMAATFLALAGLQDQQASRRIPLELLLL
                     PQRLWRRRLSFRVAPFVAMAFIQARHSPPEARLQRLLDRLARPAGLRTLARVERGENAR
                     GGYGGDNWLAAVVCLGLTCAGAPRRAVLDAVGYLRANAHPDGSWHIMQGLDLIGGSYVA
                     RGLADAGYRADPRLVRARQWLRGCQQEEAFEVYGAPPGGWGWEGPRGWPNFLDSANVLA
                     ALAAGGGEAGTGDGDGDVDTGEAGTGDGDGDVDTGEAGDAHLRRGLRWLVSRQDRKGSW
                     GTFVPDTTLPNDGPCPYVTAQSVEVLLDSGVSRRHPAVRKALDWLLAHQRADGTYEALW
                     YRGLTPGTAMVLVALGRAGLAGHPVARRARDALLRNQLADGSWGPGETGTPGDDPSPGT
                     VEETAWALRALLACGVPADDPRLRRAAEWIMTAQRPDGRWDASAVCVHIRGFAYYVDGL
                     IVDGLALKALGDYRGAVAALPYEGQEAS"
     CDS             complement(5691..6710)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlT3"
                     /product="UbiA-type prenyltransferase"
                     /protein_id="DAC74133.1"
                     /sec_met_domain="ubiA (E-value: 2.4e-17, bitscore: 53.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRGSRFGNVLAAHVRTWRPYTLWYVGLVGLAGAALAADRHTPGR
                     LAAAWLVPTLVWLAAHYLGDYLDRDLDAISKPQRPIPSGQLRPSTAVVCGVVLTCGGLA
                     VGLSVNGLTVFLLAGGVGGAMAYNGFFKARGLWGNVVRGALTGAAFVFGAMMAVRTPPL
                     ELLLFVVVFWAHDAASNLVGTLRDVAGDREGGYVTFAVRHGPRRAAGAAAALYALAVAT
                     AVAGTFLVPRDRAAYLLGILLAAVLGAYAFRMLYAAGRALTSRTALRSHEVLVVERLVL
                     AAALLVPGLGLPTALGLLVPVLVVTLTTQRVMRSRHEFSPDGRAHSADGPAAPPAFQR"
     CDS             complement(6712..7743)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 259.8; E-value:
                     4.7e-79)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlT4"
                     /product="GGPP synthase"
                     /protein_id="DAC74134.1"
                     /transl_table=11
                     /translation="MTTTDYEPPMGRTHLPDFPASPAGHDLLHRDLLRIWGGQDDQLGR
                     IAEYALVPPGKMLRPLLVLESARCAGGRPEDLTELALAVEYLHVATLIHDDIIDGDDMR
                     RGRPSVQAAFGVPSAIVAGDGLILETFATLTGARPEGVTDAAVVAVVSVLARAGVSLCR
                     GQLLESEYVGDLNCTVDQYLVMARLKTGVLFESACRIGAILATDRPEWIDALGVFGEQL
                     GTAFQVRDDLLAFDDSPALLGKPRESDLHNRRPTLPVLLAYERAGDDDRKELERVFRDE
                     RPHDDAYALVRDVVERTGAREAAGDHAARMIGRAKDSLTRLPAGKGADTLGTIADYASG
                     RRF"
     CDS             complement(7747..8598)
                     /codon_start=1
                     /note="TnlH"
                     /product="fumarylacetoacetate-like hydrolase"
                     /protein_id="DAC74135.1"
                     /transl_table=11
                     /translation="MLVCRYGDGGGRGYGRVDRDHDGDRVVPVAYDGATGRWVPRAGRA
                     RPVGEVTLLPPAEPTKIACIALNHTSGGGPAAGGGRPAGAASSPVLLKPPSSLAGPGDA
                     VGHPGAAWELKHEAELAVVIGVRCKRVRPEYAAEVVAGYTCANDLTAYAKAPPDAGNGS
                     APAAYPPLWAKHFDRFTPLGPWLATDLDPAGVEITCQVDGETRQRGSTRDLITPVHEVI
                     AVVSEHMTLEPGDVILTGTPAGSGPLSPGDRVEVSIGGIGTLRNTIAVVAADHAASEER
                     PC"
     CDS             complement(8644..9786)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 413; E-value: 1.9e-125)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlO2"
                     /product="cytochrome P450"
                     /protein_id="DAC74136.1"
                     /sec_met_domain="p450 (E-value: 1.4e-25, bitscore: 80.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPELDELRAREPVSRVRLPDGRTAWLVTRHDDVRTVLSGEKFTR
                     DMSAGSGAAATEPGRGTTRTVNMDGRAHLELRGLVSKAFGVRRIDGMRPRVQELTDRLF
                     DSLEEAGPPADLVRHVAAPLPALVICELLGFPTEDHAALSRLCDRITTVGGGPDQSAWR
                     ELSAFVDRTVRARRAGPGEGRASDPDVLSVLIRAHDEARLTEEELVSLTVVILAGGLET
                     TQTAISAGLLRLFRNPDQWKRLRDDPGLLDPAIEEILRYQPVVDLNRLQMATEDVWLGG
                     RLVPAGDLVQISINSANRDDGIFPEAARFDIARQPNPHLAFGHGAHHCLGAALARLELR
                     TVFSTILRRFPGLRLAAAPESLRWRGGHVTLGLEELPVTW"
     CDS             10342..11841
                     /NRPS_PKS="Domain: AMP-binding (9-392). E-value: 1.7e-85.
                     Score: 278.9. Matches aSDomain:
                     nrpspksdomains_DAC74137.1_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     354.8; E-value: 1e-107)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlP4"
                     /product="AMP-dependent synthetase"
                     /protein_id="DAC74137.1"
                     /sec_met_domain="AMP-binding (E-value: 6.1e-92, bitscore:
                     298.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWMAQLLERGRQRHGDRVAVLDGERQVTYAELDRRTDSLATTFL
                     AMGIERGHRVAVVSHNRLEVLETYFALGKIGAAAVPVHYGAVADEVAAVVKEYGVSAVV
                     GEEGLPGTADHPFDCPVLLYGSSAYAEAVSCRPRLPAREVPDDELLFVLQTSATTGRPK
                     GVRVDHRSLRSVTLGYLAEVMPETDIVFLHCGPLSHGAMVFPLMYMAAGATVALMRMFS
                     PLECLATIRRAQVTHLFLVPDMLRFVLKAQGSSRTGLGRLREVIYGAAPMPRPLLLEAR
                     AAWGCAFRQAYGLTEAGGVVATLPPADQDYTTGEARGPAASVGRALLGTVIRSRDGELW
                     VRGPGVMSGYWNDPGATEETLQDGWVRTGDLGTVDEQGYVHLTGRVKDVIVRGGQKIFP
                     TEVEHVLLGHPAVREACVVGTPSEEWGELPFAYVVAADDDTAALDASLRELTRRHLARY
                     KRPVHFEVVASLPRNAAGKVDRKNLRNRAAGSDRGNEHGER"
     aSDomain        10369..11517
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DAC74137.1_AMP-binding.1"
                     /evalue="1.70E-85"
                     /label="DAC74137.1_AMP-binding.1"
                     /locus_tag="DAC74137.1"
                     /protein_end="392"
                     /protein_start="9"
                     /score="278.9"
                     /tool="antismash"
                     /translation="RGRQRHGDRVAVLDGERQVTYAELDRRTDSLATTFLAMGIERGHR
                     VAVVSHNRLEVLETYFALGKIGAAAVPVHYGAVADEVAAVVKEYGVSAVVGEEGLPGTA
                     DHPFDCPVLLYGSSAYAEAVSCRPRLPAREVPDDELLFVLQTSATTGRPKGVRVDHRSL
                     RSVTLGYLAEVMPETDIVFLHCGPLSHGAMVFPLMYMAAGATVALMRMFSPLECLATIR
                     RAQVTHLFLVPDMLRFVLKAQGSSRTGLGRLREVIYGAAPMPRPLLLEARAAWGCAFRQ
                     AYGLTEAGGVVATLPPADQDYTTGEARGPAASVGRALLGTVIRSRDGELWVRGPGVMSG
                     YWNDPGATEETLQDGWVRTGDLGTVDEQGYVHLTGRVKDVIVR"
     CDS_motif       10792..10848
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DAC74137.1_0001"
                     /evalue="7.80E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="DAC74137.1"
                     /protein_end="169"
                     /protein_start="150"
                     /score="18.6"
                     /tool="antismash"
                     /translation="FVLQTSATTGRPKGVRVDH"
     CDS_motif       11350..11418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DAC74137.1_0002"
                     /evalue="4.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="DAC74137.1"
                     /protein_end="359"
                     /protein_start="336"
                     /score="31.9"
                     /tool="antismash"
                     /translation="GELWVRGPGVMSGYWNDPGATEE"
     CDS             11828..12103
                     /NRPS_PKS="Domain: PP-binding (14-81). E-value: 1.8e-11.
                     Score: 36.3. Matches aSDomain:
                     nrpspksdomains_DAC74138.1_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlP1"
                     /product="peptide carrier protein"
                     /protein_id="DAC74138.1"
                     /sec_met_domain="PP-binding (E-value: 7.5e-12, bitscore:
                     36.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENAEAVHVLARLETLLREVWDEYPAGEPVDRDASLLSLGVDSLT
                     LVILLDRVEREFRVAWDPGNPPGAFSSLRSLAELVAAGSPDTAGKP"
     aSDomain        11870..12070
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DAC74138.1_PP-binding.1"
                     /evalue="1.80E-11"
                     /label="DAC74138.1_PP-binding.1"
                     /locus_tag="DAC74138.1"
                     /protein_end="81"
                     /protein_start="14"
                     /score="36.3"
                     /tool="antismash"
                     /translation="TLLREVWDEYPAGEPVDRDASLLSLGVDSLTLVILLDRVEREFRV
                     AWDPGNPPGAFSSLRSLAELVA"
     CDS             12281..13426
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 410.1; E-value:
                     1.6e-124)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlO3"
                     /product="cytochrome P450"
                     /protein_id="DAC74139.1"
                     /sec_met_domain="p450 (E-value: 6.8e-21, bitscore: 65.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAWFRRMREEAPVSHDEETGVWHVFRYAEAVQVLGDPDTFSSDFS
                     GLTSAQEDVDLFSRGNIVRMDPPQHRKLRTLVGKAFTPRVVARLEPRIAAVTGELLDAM
                     KGSDRTELISALAYPLPVIVITELLGIPAEDRATFRRWAEALVSPEGQSGLVPNEQRVR
                     SMAAVMREMNPYSLDHIRSRRAAPKDDLISKLVTAEVDGERLDDAEMVGFVSLLLLAGH
                     ITTTVLLGNSVLCLADHPEAAAALRADPSGLPTMIEEVLRYRAPLAPTTRRTTREARIG
                     EHTVPAGQVVVTWLASANRDERQFHEPDRFDFRRRPNPHLSFGQGIHFCLGAPLARLEA
                     RIALEAMLGRWSDFTAGPGVEFHDPRGIFGPRRLPLHLRWA"
     CDS             13459..14307
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262:haloalkane dehalogenase (Score: 72.7; E-value:
                     4.9e-22)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlP6"
                     /product="alpha beta hydrolase"
                     /protein_id="DAC74140.1"
                     /sec_met_domain="PF00561 (E-value: 2.4e-17, bitscore: 53.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.9e-13, bitscore:
                     42.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANTDSTTHTLDVPGARLCYETHGSGPLLLLVGAPMGSRGFATIT
                     PLLAEDHTVVTYDPRGILRSTVEDPAREGTLEVLTDDVHRLLSALGPEPAYVFGNSGGA
                     AIGLDLLTRHPGQVRALVAHEPPLMELLPDSAQLRAAADEVYDTYVGVGRNEALKKYAA
                     LTGVERFSRPPGGGRHEVTDLDSFTPPDDVRAILDRFFLHIFRPTARYAPDIAALRAAS
                     APVVVGGGTTSKGQLSHRAAVALAGQLGTHVVDFPGDHTGFQGEPEAFAATLRRVLTGT
                     A"
     CDS             14342..15055
                     /codon_start=1
                     /note="TnlP2"
                     /product="tryptophan dioxygenase"
                     /protein_id="DAC74141.1"
                     /transl_table=11
                     /translation="MTAFSYSDYLRTDTLLSLQRTRTPPTADRAVLLAEHFFIVAHQSC
                     ELWLKQVVADLEAVAGTLSSASGAEDLELSAEYLQRASEVLRVLHDQVIVLERLPLRHF
                     AAFRPYLGTASGAQSEQFRTLARLIGDERRTGTLYEAFATAVTRLGTTVAEVCRRGTGA
                     GALHRVAEGLLDIGNGYWRWKVAHLGLTSKMLGGRPGTGATDGVDHLLRRITQPFSELR
                     THREQVHAPLAQSAG"
     CDS             15112..16581
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlP3"
                     /product="tryptophan halogenase"
                     /protein_id="DAC74150.1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.3e-132,
                     bitscore: 433.4, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATYLKAAFGERIQVTLVESEQVSTIGVGEATFSTVRHFFRFLG
                     LAEHEWMPECHASYKLAIRFEDWRAEGHYFYHPFERPRTVNGFSLAEWWQHLRPGDRFD
                     RDASVLAALCDARSSPKYLDGTLFEMAGEDPTQFPYAYHFDATLLARFLRGYGTRRGVR
                     HVVDDVLDVRLDERGHIRNVLTKEHGELAGDLFVDCTGFRGMLLNKALGVPFLSYQDSL
                     PNDSAVALRVPVDVARRGMRPCTTATAQAAGWIWTIPLLDRLGTGYVYASDYCSPEEAE
                     RTLREFVGPEADDVTANHIRMRIGRSAQSWAGNCVAIGLSSGFVEPLESTGIFFIQNGI
                     EQLVRYFPDGRDDERLRQAYNRQVGHVMDGVREFLVLHYYAAARDDNQYWRDAKTRPMP
                     DALAERIEQWHTSLPDADSVYPYFHGFEPYSYTAMLLGLGGIRTRPLPVLARLDGTDAV
                     KEFHRIRQQADSLVDRLPSQYDYLAQLRGGA"
     CDS             complement(16629..17222)
                     /codon_start=1
                     /note="TnlR2"
                     /product="TetR family regulator"
                     /protein_id="DAC74142.1"
                     /transl_table=11
                     /translation="MPTGVAIRDVRRQLFGAAERVLLRGGPNALTSREVTTEAGCAKGV
                     LHRHFADFDTFLAELVRDRMGRIDDQAAALRDRAGSGTVVDNLAGALTDLFGPVTVGIV
                     NLVVSRDELRGRLRRTTPTGIPVLTEATAMIASYLVAERDLGRIAADADIDTLSPMLIG
                     SGHLLFADRQATAPEPTAVRKTVSAVVSGVLRQP"
     CDS             17367..18527
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 418.1; E-value:
                     5.5e-127)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlO4"
                     /product="cytochrome P450"
                     /protein_id="DAC74143.1"
                     /sec_met_domain="p450 (E-value: 2.3e-28, bitscore: 89.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYGVADPVRELWRQAPVREITTETGMKGWLVTGMEEVRVALSDPR
                     FSRAEARRIGAVVMPSAVFEKPGINDLDGAEHTRLRRLVAGAFSARRIRALRPRVQRIT
                     DELITALAAAGPPADLVAGLCRPLPLTVIFEILGVPQQDRARFSGWADRVMAAGAYSPE
                     ESLKALHAVVDYMTELVDAKRRAPDDSLLQDLIAARDEHDRLSEQELVHLGCGLLMAGN
                     ESTATMLGKGLLALLDNPDQLAALRADPSLLPSAVEEVLRYAPLAARPYGGQVRATTCD
                     VELGGVTIPAHSVVFAAVPAANLDPGTFPDPVRFDITREGAAEHVTFGYGPHRCLGAQL
                     ARMELEVAFGSLLAAFPRLRPAVPVEELSHAEGRLMTGLLELPVTW"
     CDS             18649..19473
                     /NRPS_PKS="Domain: oMT (15-217). E-value: 4.9e-46. Score:
                     148.6. Matches aSDomain: nrpspksdomains_DAC74144.1_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 189.9; E-value: 9e-58)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlM1"
                     /product="methyltransferase"
                     /protein_id="DAC74144.1"
                     /sec_met_domain="PCMT (E-value: 6.6e-09, bitscore: 26.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGFYNDISGLLTELFGGSLHEGYWESPSDRSTMAEASQRLTDLL
                     TEKLKAGPGDTVLDVGCGSGAPAIRLARVTGARVVGITNSDVQIQAAVRNAQDAGMGEQ
                     VTFRCEDATVLDFPAGSFDGVLMIESIFHLPDRLGALREAAKVLKPGGRLALTDLLDLT
                     PVRHGMAEAMGDLAEHGHEHGHAPLVARPIPLRRYETLLEEAGLVPVELTDVTEHTVAP
                     TLACIRKKLDEDHDRLVETFGSQVVKQYETVLPLLESAGFGYAVVVAEVPGG"
     aSDomain        18694..19299
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DAC74144.1_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="4.90E-46"
                     /label="DAC74144.1_oMT.1"
                     /locus_tag="DAC74144.1"
                     /protein_end="217"
                     /protein_start="15"
                     /score="148.6"
                     /tool="antismash"
                     /translation="FGGSLHEGYWESPSDRSTMAEASQRLTDLLTEKLKAGPGDTVLDV
                     GCGSGAPAIRLARVTGARVVGITNSDVQIQAAVRNAQDAGMGEQVTFRCEDATVLDFPA
                     GSFDGVLMIESIFHLPDRLGALREAAKVLKPGGRLALTDLLDLTPVRHGMAEAMGDLAE
                     HGHEHGHAPLVARPIPLRRYETLLEEAGLVPVELTDVTE"
     CDS             19588..20397
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 58.9; E-value:
                     8.8e-18)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlM2"
                     /product="methyltransferase"
                     /protein_id="DAC74145.1"
                     /transl_table=11
                     /translation="MPTLPENQPHRQRQVAESFGTDAERYDRARPRYPEALVERIVADS
                     PGVTVLDVGSGTGIAARQFQAHDCTVLAVEPDERLAELARQLGVETDVATFEAWEPAGR
                     EFDAVVAAQAWHWVDPVAGAAKAARVLRPAGRLAVFWNVFQFPPDVADVVAEVCERVMP
                     NAPFSFTAMTKGAMDGYQEFFAKSADGIRTAGGFGEPEQWRYDWEWTYTKDAWLDQMPT
                     LGAFTRLPEDKMAEVLRGVGDAIDAMGGSFTMGYATVAVTARRTDAP"
     CDS             20456..21451
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 85;
                     E-value: 1.1e-25)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlE"
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="DAC74146.1"
                     /transl_table=11
                     /translation="MRVLVLGGTHYVGRALVEAALARGDDVSTLNRGLSAPAAKGVETL
                     IADRTDPRALRRAIGDQKWDAVVDTWNGAPRVIADSSALLADRVRHFGYVSSWVVYRPP
                     VPHGADESAAVIDGDPDDSADGFYPTAKRGAELGVLRAFGDRALIARPGPMLGPYEDVG
                     SLTWWLRRIERGGRVLAPGAPDDPLQYVDVRDHAVWMLDAAERGIGGTFNTVCPRGRHT
                     MGELLETMCRVTGSDAELVWAGDDILMAEGVRPYLDIPLWLPAAMRGGIHDVDVTAAHD
                     AGLDTGRPLEDTLADTWSWLRREGEPPWQQTDTRRGLDPATEQRVLDKVG"
     CDS             21456..22277
                     /NRPS_PKS="Domain: oMT (20-216). E-value: 3.8e-48. Score:
                     155.6. Matches aSDomain: nrpspksdomains_DAC74147.1_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 191; E-value: 4.4e-58)"
                     /gene_kind="biosynthetic-additional"
                     /note="TnlP5"
                     /product="methyltransferase"
                     /protein_id="DAC74147.1"
                     /transl_table=11
                     /translation="MRQQTDEAGFYNDTSEFLAELSGGSLHMGYWESPSDRSTMAEASQ
                     RLTDLMTEKTKAGPADRVLDIGCGTGAPAIRLARTTGAQVVGITDSPVQARLAVRSAED
                     AGIGDRVTFRREDAMDLPFPAQSFDVVWLLESLMAMPDRLGALRQAARVLVPGGRLALT
                     DFLDRAPAPATGRRTPGEHEGSTLMTKLIPLADYDSLLEQAGLVPVETTDITDHTVERT
                     LTCMRQKLTEDREDLVRRFGAPVVDQFDAIVARLRAVGLGYGLVVATRPVR"
     aSDomain        21516..22103
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DAC74147.1_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.80E-48"
                     /label="DAC74147.1_oMT.1"
                     /locus_tag="DAC74147.1"
                     /protein_end="216"
                     /protein_start="20"
                     /score="155.6"
                     /tool="antismash"
                     /translation="LSGGSLHMGYWESPSDRSTMAEASQRLTDLMTEKTKAGPADRVLD
                     IGCGTGAPAIRLARTTGAQVVGITDSPVQARLAVRSAEDAGIGDRVTFRREDAMDLPFP
                     AQSFDVVWLLESLMAMPDRLGALRQAARVLVPGGRLALTDFLDRAPAPATGRRTPGEHE
                     GSTLMTKLIPLADYDSLLEQAGLVPVETTDITD"
     CDS             complement(22341..23480)
                     /codon_start=1
                     /note="Orf2"
                     /product="alpha beta hydrolase"
                     /protein_id="DAC74148.1"
                     /transl_table=11
                     /translation="MSPRFLRLAAVSLALLGALVVPGVPSAAAASAESSVRTTSGPELP
                     APTGALRIGSRSLHLKDTSRPDPWKPGKDFRELMATVWYPAVRPSGRAAPFMSAQLSSA
                     AFGTDALSTVRTHSTVDAAALPGARPLVVLSPGYGMTRVSLTSLGEELASRGYVVAALD
                     HTYEAFVEFPGGRLEPCSMCTGQGNADVVRSRVKDIHFLLDQLTGPGSGLPVDGSRIAV
                     VGHSIGGASAVETLSEDPRVDAAVNMEGTFFTERPQEPVSRPVLLLGAQWPTAGGTPAA
                     NWVDRWGGLAGWKRWLSVPTAGHLSFSDAHWLYEHFDLSGVIPPELEPQLFGTLSGDRA
                     TVITRAYVGAFVDRHLRGVPRPLLDGPCAAFPEVAFVRP"
     CDS             complement(23541..24752)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 331;
                     E-value: 1.2e-100)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orf3"
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="DAC74149.1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 4.9e-19,
                     bitscore: 59.1, seeds: 500, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 9.2e-37, bitscore:
                     117.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTERTLREAADRFGTPLYVYDLAELRRRAAELWSVLPEAASLLYS
                     LKANPHPSVVAELRRAGCRAEVSSPGELAVALEAGHAAEEILYTGPGKSAAEIEEALAR
                     GVTSFSCESAAELRRLGRATAATGTRAGALLRLQPPTGSKAGLSMGDGRQFGFTPEDAV
                     RACAEVPSGVEVRGCHVYLGSQFPDVEALRDGFATARSTMELVAREAGIPLGVVDLGGG
                     FPWPYATPGAGAVLTGLREELDKLLSTWATGPAPQVYFESGRRLVASAGHLLTRVLDVK
                     ERPEGTIVVLDAGINVLGGMSGLGRVLRPATGFVNLSAGDDREPVTADVVGPLCTPLDR
                     LAVRTTLPRPREGDLLCVPNVGAYGPTASLTRFLSRPPAVEAVYDGDQLVSASRPVVSY
                     EAVE"
ORIGIN
        1 atgaacgccc agcacctcac ggaactgttc ttcgccctgg cggccgtcgt gctcctggcg
       61 cgactgctcg gcgccgtggc gcgccggttc gaccagccgg cggtcatcgg tgaggtgctg
      121 gccggcgtcc tgatgggccc gacactgttc ggtggcgcgg tctccgacca cctcttcccg
      181 gccggtatcc ggccgagcct gggcgtcctg gccgccgtcg gggtcgccgt cttcatgttc
      241 atcgtcggcc tggagtggga cccggccctg gccaggggct ccggcgggtt cgcggtcacc
      301 gtgtccctga gctccgtcct cctgccgttc ggcctgggcg ccgcactggc cgtgtacctc
      361 atgcgggagt acgacacccc cgacaaggcc gcgttcgtgc tcttcatggg catcgccatg
      421 tcgatcaccg cgttcccggt gctggcccgc atcctcaccg accggggcat ggagcggacg
      481 acgctgggcg tgctggcgct cgcctgcgcg tccatcgacg acgtactggc ctggtcggtg
      541 ctcgccgggg tggccgccct gagcggggcg gcgggcccgg gccccgcgag gatgctcctc
      601 gccctgccgt acgtgctcgg catgctcttc gtcctgcggc ccctgctgcg ccgggtcctg
      661 gcgcacgggg gcaccgtccg gctcaccccg gcgtggacgg cgtgcgccct cgtggggatg
      721 ctggcgtccg ccgccacgac ggagtgggtg gggctgcact tcatcttcgg ggcgttcctg
      781 ttcggcgccg tcatcccgcg tgagcggacg gcgcggctgc gcgccgggat ccgcgaccag
      841 ctcggccggc tcagcgacgt gctgctcctg ccggtcttct tcgtggtcgc cgggctcaac
      901 gtcgacctgt ccgggctgag cgtgggcgga ctcggcgacc tgggcctgat cctcctggtg
      961 gccatcgggg ggaagttcgc cggcgcgttc ctcgcggccc gcgcgcacgg gatgccgtcg
     1021 cggcagtccg cggcactggc caccctgatg aacacccgtg gcctgaccga gctcatcgcc
     1081 ctgagcgtgg ggctgaacct ggggatcatc cagcaggacc tgtactcgct catggtggtc
     1141 atggcggtcg tgacgaccgc gatggccgga ccgctgttgc ggtggctcct gccccggcgg
     1201 ctcatcgagg cggaagccgc cagggaatcc gtccccgccg actccaccga cgtgcgaccg
     1261 gacgccccca cccggacttc acccccaccg gggtgagccg gcagggcctc ggagaactgg
     1321 tccggggccg cagcctgccg gaacaacgac agccagtctc acgtacatgc gaatgcgagg
     1381 tgttcagtga ccaggctagc cagcgaacca tcactcaccc cgaggcagac ggaagtggtg
     1441 aggctcgccg ttctgggcct caccgcgaag gagaccgccc gtcgactggg catatcgaag
     1501 aacacggtgg acgagcacct gcgcgaggcc agacaccgcg tcggggcggc caccaaatcc
     1561 cggctcatcg gctgggccgt cgcctccggg atcgtcccgt tctagaggca agagggactt
     1621 catcgagcgg cggccggcct gacgaacggc cggccggccg ccgctcgatg tgctctcagt
     1681 agggctcctt cgcgttcacc cgggccggcg cgtagcgctc acccggcttc ggccggtacg
     1741 gggaccaccg gggcttattc ccggtcgggt cgtccccgag caccaccacc cgcaggcccg
     1801 tacggcgttc ctcgtagtcg tcgacggcgt agtgctgcgt gacccggttg tcccagatcg
     1861 ccacgtcgcc cggccgccac tggtaccggc aggtgaactg cggtgaggtg gagaactcgg
     1921 tgaggaactg cagcagcgcg tcactctcgt tccggctgag ctgcacgatg tgcgaggtgt
     1981 gggcgcggtt gacgaacagc gcccggcggc ccgtctccgg gtggacccgc accacggggt
     2041 gctccgcccg gctgtccagc cccgggatgt ggatggcgtg aatcgccgtg aggccgtcga
     2101 gcagctcgcg catcggggcg gacagggact cgtaggccag atactggttg gaccacatcg
     2161 tgtcgcctcc cctcccgggg ctgcggacga tctgcaggac ggacccgatc ggcggattcg
     2221 gcgagtacgt catgtcggtg tgccagatcg ggatcttgcc gtcctgctcc gagtcgatga
     2281 tctgtatctc cggatgcccg tcgaggtgcg gcagatacgg atggacctcg agctccccga
     2341 accggcggcc gaaggcgatg cgcgactcgg acgaccaccc ctcctgctcc ggcaggaaga
     2401 gcaccagata ccgcagcagc agccggcgca gttcggcgaa ctcctcgtcg gtgatgtcct
     2461 ccaggcgtac gccgagcacc tcggctccca gagcaccgga cagcggacgg acatcgaagg
     2521 ccgtcctgag tgactctgac atcttcccac ccttcttccc tcgtggatca cttcggcgcc
     2581 ggcagccggg gcaccttgcg gtcggggagc acccccagct gaacgagccg gtccacggtg
     2641 ccgagagggc gcataccgag gcccgacatg ttgtaggtgg tcagccggcg caagcgggcg
     2701 ctcctggccg tcccggtcag cagccgcagg cccagcgccc tgcccaggcc ggaggtgctc
     2761 gtcatcatgc gcgcggcacg gtgactcatg acgtggatgt cccggatcct gtcgcggcgc
     2821 ccggcctcgt acgcccgcag cgcccggtcg accgcctccc gcccggtgac gtcgacgccg
     2881 gcgagccggt ccgcgaggac ctgggcgtct ccgatggccg tgttcatccc ctgcgccgcc
     2941 aacgggtgca cgccgtgtgc ggcctcgccg atcagggcga tgcccggccg taccagggac
     3001 ggggcccggt actgccacac cggcagcaac tgcctgcggt ccagtccctc cttgaacgcc
     3061 gggctcaacg gcccgagcgc gggtacgccg gcgatcagct cgtcgcacca ctgctgcagt
     3121 cgcgcccggt ccgcgcccct gatctcgtcc ggcgccacct ggacgtagac ccgtgtccgt
     3181 cggtccggca gcggatagac catgaccagc ccgcggtccg tgacgtacgc ggacacctcg
     3241 tcgtccaggt ccggcgtacc cgccagttcg aacgacagga gcttgtggcc gtacgcgacg
     3301 gggctcgcgc tcagtcccga caggcggcgc acgcgcgagg acatgccgtc ggcggccacc
     3361 acgagccggg cacggacgtc gtactcgctc ccgtcgcgca ccgcccgtac gccgacgacg
     3421 cggccgtcgc cgtccttgac gacgtccttc accagcaccc cgcgctgcca gtggacggtc
     3481 gtgccgagcg actccccgag acactccagg atcgtcgtgt agtcgtggga cagcatccag
     3541 ggccgctcgc cgccgagcac cccgaagtcc atcgtcagca gttcggcgcc gtcggccctc
     3601 ctggtgacga gccggttgag gcggaccgcc cccctggcct ccagggcggg gagcgcgccc
     3661 cacgagtgca gggtgttcag ggagccgggc tggaggacct cgcccttcca gaccggtggc
     3721 tgccgccggt tcttctccag cagggcgacg tccagcccca gccggcccag cgcacaggcc
     3781 gccgccaggc ctgccactcc cgccccgcag accaccacgt ccgcgtccac ggtgcccgca
     3841 ggcgcgttcc ctgtcgtcat gacgcctcct gcccctcgta cgggagtgcg gccaccgcgc
     3901 cgcggtagtc cccgagcgcc ttcagggcga gtccgtcgac gatcaggccg tccacgtaat
     3961 aggcgaagcc gcggatgtgc acgcacaccg cactggcgtc ccaccggccg tccggccgtt
     4021 gcgcggtcat gatccattcg gccgcgcggc gcaggcgcgg gtcgtcggcc ggcaccccgc
     4081 aggccagcag cgcccgcagc gcccacgccg tctcctccac cgtccccggc gaaggatcgt
     4141 cgcccggcgt acccgtctcg ccagggcccc aggaaccgtc cgcgagttgg ttgcgcagca
     4201 gggcgtcacg ggcgcgccgg gcgacggggt ggccggcgag tccggcgcgg ccgagggcca
     4261 cgagcaccat ggcggtaccc ggggtgagcc cccggtacca cagcgcctca taggtgccgt
     4321 cggcacgctg gtgggcgagc agccagtcga gtgccttgcg taccgcgggg tgccgacggg
     4381 aaacgccgct gtcgagcagg acctcgacgg actgcgcggt gacgtagggg caggggccgt
     4441 cgttggggag cgtggtgtcg gggacgaagg tcccccagga acccttgcgg tcctgccgcg
     4501 agaccagcca gcgcagcccg cggcgcaggt gcgcgtcgcc cgcctcgccg gtgtccacgt
     4561 cgccgtcgcc gtcgccggtg cccgcctcgc cggtgtccac gtcgccgtcg ccgtcgccgg
     4621 tgcccgcctc gccgccgccc gccgcgagcg cggccagcac gttggcgctg tcgaggaagt
     4681 tcggccaacc tcgcggcccc tcccagcccc agccgccggg aggagcgccg tagacctcga
     4741 acgcctcctc ctgctgacag ccgcgcagcc actgcctcgc ccgcaccagc cgggggtcgg
     4801 cgcggtagcc ggcgtccgcc aggccgcgtg ccacgtacga cccgccgatc aggtcgaggc
     4861 cctgcatgat gtgccaggac ccgtcggggt gcgcgttcgc ccgcaggtag ccgacggcgt
     4921 cgaggaccgc gcggcgcggc gccccggcac aggtgaggcc caggcacacc accgcggcca
     4981 gccagttgtc cccgccgtag ccgccgcggg cgttctcgcc tcgttccacc cgcgcgagcg
     5041 tgcgcagccc ggcgggcctg gccagccggt ccagcagccg ctgaagccgc gcttccggcg
     5101 ggctgtggcg cgcctggatg aaggccatcg cgacgaaggg cgcgacgcgg aaggacaggc
     5161 ggcgtcgcca cagccgctgg ggcagcagga gcagttcgag cgggatgcgc cgggaggcct
     5221 gctggtcctg gagcccggcg agcgcgagga acgtcgcggc catgtgggcc atgccgggat
     5281 cggtgagcgc ctcggtcccg ccgtacgact tcaccaggtc cagggcccgc tgtacgggtt
     5341 cccgggaggt gtgcggggac accaggtgca gcgacgccgc cgcgatcacg gtgggtacga
     5401 gctgggtgga ggcaccggcg accccgcccc agccgccgtc ggcgttctgg gcgcccgcca
     5461 gccaggcggc tccccgttcg atgaggtcgt tcgagcgctc gcggtcggcg acgtgcagcg
     5521 cggccagcgc gccggccgta ccgagcacgg cggtgggccg cctgttgggc caggagccgt
     5581 cgggccgctg cacctcgaac aaggcctcgg cggccttcgc gaccgacctc gcgaccgact
     5641 tctcgacgcg accgtccaca gctgagcaca tgggggactg tcctccttct ctagcgctgg
     5701 aaggcgggcg gagccgcggg gccgtctgcg gagtgtgcgc ggccgtccgg cgagaactcg
     5761 tgccgggagc gcatcacacg ctgagtggtg agagtgacga cgagtacggg tacgaggagc
     5821 ccgagcgccg tcggcagtcc gaggcccggc accagcaggg cggcggccag cacgagccgc
     5881 tcgacgacga gcacttcgtg ggagcggagg gcggtgcgcg aggtcagggc acgccccgcg
     5941 gcgtacagca tccggaaggc gtacgccccg agcaccgcgg cgagcaggat cccgaggagg
     6001 tacgccgccc ggtcgcgcgg cacgaggaac gtccccgcca ccgccgtcgc gacggccagg
     6061 gcgtagaggg ccgccgcggc gcccgccgcc cgccgcggcc cgtggcgcac cgcgaaggtg
     6121 acgtaaccgc cctcgcggtc cccggcgacg tcccgcagcg tcccgacgag gttggacgcg
     6181 gcgtcgtggg cccagaacac caccacgaac agcagcagtt cgagcggtgg ggtccgtacg
     6241 gccatcatcg cgccgaacac gaaggccgcg ccggtgagcg cgccgcggac aacgtttccc
     6301 cacagccccc gcgccttgaa gaagccgttg tacgccatcg ccccgccgac cccgccggcc
     6361 agcaggaaca ccgtgagccc gttgacgctc aggccgacgg ccagcccgcc gcaggtcagg
     6421 accacaccgc agacgaccgc ggtggagggc cgcagctgcc ccgacggtat ggggcgttgg
     6481 ggcttgctga tcgcgtcgag gtcgcgatcg aggtagtcgc ccagatagtg cgccgccagc
     6541 cacaccaggg tgggcacgag ccatgccgcg gccaggcgcc cgggcgtgtg ccggtcggcg
     6601 gccagggccg cgccggccag gccgaccaga ccgacgtacc agagggtgta cgggcgccac
     6661 gtccgcacgt gcgcggcgag gacgttcccg aaccggctgc cgcgtcgcat gtcagaacct
     6721 tctcccggac gcgtagtccg cgatggtccc cagggtgtcg gcgcccttcc ccgcgggcag
     6781 cctcgtgagg ctgtccttgg cccgtccgat catccgcgcg gcgtggtccc cggccgcctc
     6841 acgggcgccg gtccgctcca cgacgtcgcg caccagcgcg taggcgtcgt catgggggcg
     6901 ttcgtcgcgg aagacgcgct ccagctcctt gcggtcgtcg tcgccggccc gctcgtacgc
     6961 cagcagcacc ggcagggtgg ggcggcggtt gtgcaggtcg ctctcgcgcg gtttgccgag
     7021 gagcgcgggg gagtcgtcga acgccagcag gtcgtcccgg acctggaacg cggtgcccag
     7081 ctgctccccg aacacgccca gggcgtcgat ccactccggc cggtcggtgg cgaggatcgc
     7141 cccgatgcgg caggccgact cgaagagcac accggtcttc agccgggcca tcaccaggta
     7201 ctggtccacg gtgcagttca ggtcgccgac gtactccgac tccagcaact ggccgcggca
     7261 caggctcact ccggccctgg ccagcacgga aaccaccgcc acgacggcgg cgtccgtgac
     7321 accctcgggc cgcgcgccgg tcagggtggc gaaggtctcc aggatcagcc cgtcgccggc
     7381 gacgatggcg gagggaacac cgaaggcggc ctggacggaa ggacggccac ggcgcatgtc
     7441 gtcgccgtcg atgatgtcgt cgtggatgag ggtggccaca tgcaggtact cgacggccag
     7501 ggccagttcg gtgaggtcct ccggacggcc tccggcacac cgtgccgatt cgagtaccag
     7561 cagcgggcgg agcatcttcc cgggcgggac cagggcgtac tcggcgatgc ggcccaactg
     7621 gtcgtcctgt ccgccccaga tcctcagcag atcccggtgc aggaggtcgt gcccggcggg
     7681 cgacgcgggg aagtccggca gatgtgtccg gcccatgggg ggttcgtagt cagtcgtcgt
     7741 catcgttcaa cacggccttt cttcactcgc tgcgtgatcc gcggcgacca cggcgatggt
     7801 gttgcggagc gtgccgatgc cgccgatcga cacctcgacc cggtcgccgg gcgacagcgg
     7861 cccggagccc gcgggcgtcc cggtgaggat cacgtcaccg ggctccagcg tcatgtgctc
     7921 gctgaccacg gcgatgacct cgtggaccgg ggtgatgagg tcgcgggtgc tgccacgctg
     7981 cctggtctcg ccgtccacct ggcaggtgat ctcgacgccc gccggatcca ggtccgtcgc
     8041 cagccaggga cccaggggcg tgaagcggtc gaagtgtttc gcccagaggg gcgggtacgc
     8101 cgccggcgcg gaaccgttgc ccgcgtccgg tggggctttc gcgtacgccg tcaggtcgtt
     8161 cgcgcacgtg tagcccgcca cgacctccgc cgcgtactcg gggcgaaccc gcttgcagcg
     8221 caccccgatc acgaccgcca gctcggcctc gtgcttcagc tcccaggcgg ctcccgggtg
     8281 gccgacggcg tccccgggcc cggccagtga cgacggcggc ttcagcagca cgggggagga
     8341 ggcggcgccc gccgggcgcc cgcccccggc agccggtccg ccgccggagg tgtggttgag
     8401 ggcgatgcac gcgatcttgg tcggctcggc gggcggcagg agcgtgacct caccgaccgg
     8461 gcgcgcgcgg cccgcgcgcg gcacccagcg cccggtcgcg ccgtcgtacg cgacggggac
     8521 cacgcggtca ccgtcgtgat cacggtcgac gcggccgtat ccgcgtccac cgccgtcgcc
     8581 gtatctgcag acaagcatga tggaacgttc cttcctggcc gtggaggggg cgcgaggagg
     8641 gcctcaccag gtcacgggca gttcctccag gcccagcgtc acgtggccgc cccgccagcg
     8701 caggctctcc ggcgccgccg ccaggcggag ccccgggaag cgccggagga tcgtcgagaa
     8761 caccgtcctc agttcgagcc gcgccagggc cgcgccgaga cagtggtgcg ctccgtggcc
     8821 gaacgcgagg tgcgggttcg gctgccgcgc gatgtcgaag cgtgccgcct cggggaagat
     8881 cccgtcgtcg cggttggcgg agttgatgga tatctgcacg aggtcgcccg ccggcacaag
     8941 ccggccaccc agccatacgt cctcggtcgc catctggagg cggttgaggt cgacgaccgg
     9001 ctggtagcgg agtatctcct cgatcgccgg atcgaggagt cccgggtcgt cgcgcagcct
     9061 cttccactgg tcggggttgc ggaagagcct gagcagcccg gcgctgatcg cggtctgcgt
     9121 cgtctccagc ccgcccgcca ggatgacgac ggtgagggag accagctcct cctcggtgag
     9181 gcgtgcctcg tcgtgggcgc ggatcagcac gctcagcaca tcgggatccg acgcgcggcc
     9241 ctctccgggc cccgcgcgcc tggcccggac ggtgcggtcg acgaaggcgc tgagctcccg
     9301 ccacgccgac tggtcggggc cgccgcccac ggtggtgatg cggtcgcaca accggctgag
     9361 cgcggcgtgg tcctcggtgg ggaatccgag cagctcgcag atgacgaggg ccggcagcgg
     9421 agcggcgacg tgccggacca ggtccgcggg cggccccgcc tcctccaagg agtcgaacag
     9481 ccggtccgtc agttcctgga cacgcggccg catgccgtcg atccgccgta cgccgaacgc
     9541 cttcgacacc agtccccgca gttcgaggtg cgcacggccg tccatgttga cggtacgcgt
     9601 cgtgccgcga cccggctcgg tggccgccgc gccgctcccc gccgacatgt cgcgggtgaa
     9661 cttctcaccg gagagcacgg tgcgcacgtc gtcgtgacgg gtcacgagcc aggcggtcct
     9721 gccgtccggg aggcggacgc gggagacggg ctcgcgcgcc cgcagctcgt ccagctccgg
     9781 tggcaggtcg cccgcgtggt ccgccgcgtg tgggtagtcg agtatgtggt ccatggcgtc
     9841 attccgatct gtgcggtgtg gcctgtgacg gaatgaagaa aggcgatcgg gaggaggtca
     9901 cacccgaggc cggccggaag agcagcacgg acctgcgcga cgtcatcagt ttcccccgtg
     9961 acgaatggac aagcgtgatg atggcgtggc cgcatcgccc ggttgcgatg cggccacgcc
    10021 ggaatcgact cacgcttgga tcgctttgta ccaatcgctt gtgtaccaaa ggcacgttgc
    10081 cggacagcgt tggccacaac aaccctgatt ttgcgggggt acctatgggt ccgcacgtat
    10141 gttagggtcc cgccccctcg atcgcccccc accggcaggc gatcccttta gcagatgtcc
    10201 cgctgctgag gtacccccgc aaaatgaggg ttgttggcgc ggggagctgt ccggcaacgt
    10261 gcctttcgcg atcaactggc gaaatatctt cccagaggtg ttgcgccggg aatcaggccg
    10321 agtcaggggg gagatctcgt catgtcctgg atggcacagc ttctggagag aggccggcag
    10381 cgccacggcg accgggtcgc ggtcctcgac ggggaacgac aggtcaccta cgccgagttg
    10441 gaccgccgga ccgacagcct ggccaccacc ttcctggcca tgggcatcga gcgcggccac
    10501 cgggtcgcgg tcgtctcgca caaccgcctc gaggtgctcg agacctactt cgccctcggc
    10561 aagatcggag cggcggcggt acccgtccac tacggggccg tcgcggacga agtcgccgcc
    10621 gtcgtcaagg agtacggcgt ttccgccgtc gtcggggaag agggactccc ggggacggcg
    10681 gaccacccct tcgactgccc cgtcctgctg tacggaagca gcgcctacgc ggaggccgtc
    10741 tcgtgccggc cccgcctccc ggcgcgtgag gtccccgacg acgagctgct gttcgtcctc
    10801 cagacctcgg cgaccacggg ccggcccaag ggcgtccgcg tcgaccaccg ctcgctgcgc
    10861 tcggtgaccc tgggatacct ggccgaggtc atgccggaga cggacatcgt cttcctgcac
    10921 tgcggcccgc tgtcccacgg ggcgatggtg ttcccgctca tgtacatggc cgccggtgcg
    10981 acggtggcgc tcatgcggat gttctccccg ctggagtgcc tcgccacgat ccgccgcgca
    11041 caggtcacgc acctcttcct cgtaccggac atgctcaggt tcgtcctgaa ggcccaaggg
    11101 tcctcgcgaa ccggcctcgg ccgcctccgg gaggtcatct acggcgcggc gccgatgccc
    11161 cggccgctgc tcctggaagc gcgggcggcg tggggctgcg ccttccgcca ggcgtacggc
    11221 ctgacggaag ccgggggcgt cgtcgcgacg ctcccgcccg ccgaccagga ctacacgacc
    11281 ggagaagccc ggggccctgc cgcgtccgtg ggccgggccc tcctgggcac cgtcatccgg
    11341 agccgcgacg gcgaactgtg ggtgcgcggc cccggcgtca tgagcgggta ctggaacgat
    11401 cccggcgcca cggaggaaac cctccaggac ggctgggtgc gtacgggcga cctcgggacg
    11461 gtcgacgagc aggggtacgt ccacctcacc gggcgcgtga aggacgtcat cgtccgtggc
    11521 ggccagaaaa tcttccccac ggaggtcgag cacgtcctcc tcggccatcc cgcggtgcgc
    11581 gaggcctgcg tcgtcgggac accgagcgag gagtggggcg agcttccgtt cgcctatgtg
    11641 gtcgcggcgg acgacgacac cgcggcgctc gacgcgtccc tgcgggaact gacacgccgg
    11701 catctcgccc ggtacaaacg ccccgttcat ttcgaggtcg tcgcgagtct gccgcgcaat
    11761 gccgccggaa aggtcgaccg gaaaaatctc cgcaaccggg cagccggcag tgacaggggg
    11821 aatgagcatg gagaacgctg aagcggttca cgtcctggcc cgtctggaaa ccctgctgag
    11881 ggaagtctgg gacgagtatc ccgccggtga gccggtggac agggacgcat cgctcctcag
    11941 cctcggagtc gactcgctca ccctggtgat tctgctcgac cgagtcgaaa gagaattccg
    12001 tgtcgcatgg gatcccggca atcctcccgg cgctttcagt tcactgcgct cgctcgcgga
    12061 actggtggcg gcgggaagcc cggacaccgc ggggaaaccg taaccgccat gctccggcgg
    12121 aggcggacga tcaccggtcc cttcccggcg tggcgggccg acccccgcga accggccggc
    12181 cacatcacca acgaccagga agagaggtgc cgccatgacc gggaccgaac gtgccgtcgg
    12241 gccggccgcc gtccagcagc tcgatgagac cgggacgaca ctggcctggt tcaggcggat
    12301 gcgggaggag gccccggtca gccacgacga ggagaccggc gtctggcatg tcttccggta
    12361 cgccgaggcc gttcaggtcc tcggtgatcc cgacaccttc tcgtccgact tcagcggcct
    12421 cacctccgcc caggaggacg tcgacctctt ctcccggggc aacatcgtcc ggatggaccc
    12481 gccccagcac cgcaagctgc gcaccctggt cggcaaggcg ttcacccccc gcgtggtggc
    12541 ccggctggag ccccgtatcg ccgctgtcac cggcgagttg ctggacgcca tgaaggggtc
    12601 ggaccggaca gagctgatct ccgccctggc ctaccccctg ccggtgatcg tcatcaccga
    12661 gctcctgggc atcccggccg aggaccgcgc cacgttccgg cgctgggccg aggccctggt
    12721 gtcaccggag gggcagtcgg gcctcgtacc caacgagcag cgggtgcggt ccatggcggc
    12781 cgtcatgcgc gagatgaacc cctactccct ggaccacatc cgctcccgcc gtgccgcgcc
    12841 caaggacgat ctgatcagca agctcgtgac cgcggaggtg gacggggagc gcctggacga
    12901 cgcggagatg gtcgggttcg tgagcctgct gctgctcgcc ggccacatca cgaccacggt
    12961 gctgctgggc aactccgtgc tgtgcctggc cgaccacccg gaggccgccg cggcgctgcg
    13021 cgccgacccg agcggcctgc ccaccatgat cgaggaagtg ctgcgctacc gcgcaccgct
    13081 ggccccgacc acgcgcagga ccacccggga ggcccggatc ggtgagcaca ccgtcccggc
    13141 gggccaggtg gtggtcacct ggctcgcctc ggccaaccgg gacgagcggc agttccacga
    13201 gccggaccgc ttcgacttcc gccgccggcc caatccgcac ctgagcttcg ggcagggcat
    13261 ccacttctgc ctcggcgccc ccctggcccg gctggaagcc cggatcgccc tggaggcgat
    13321 gctcggccgc tggagcgact tcacggccgg ccccggagtc gagttccacg atccacgagg
    13381 gatcttcggc cccaggcggc tccccctcca cctgcgctgg gcctgacctt ggagacggaa
    13441 ggaaaggaag agccgaccat ggcgaacacc gactcgacca cccacacgct ggacgtcccg
    13501 ggcgcgcgcc tgtgctacga gacccacggc tccggcccgc tgctcctgct ggtcggcgcc
    13561 cccatgggca gcagagggtt cgcgacgatc acgcccctgc tcgccgagga ccacaccgtc
    13621 gtgacgtacg acccgcgcgg catcctgcgc agcaccgtcg aggacccggc gcgggaaggg
    13681 acactggagg tgctcaccga cgacgtccac cgcctgctgt ccgccctcgg ccccgaaccg
    13741 gcctatgtgt tcggcaacag cggaggcgcc gccatcggcc tcgacctgct cacccggcac
    13801 cccggacagg tccgcgccct ggtggcccac gaacccccgc tgatggaact gctgcccgac
    13861 agcgcgcagt tgcgtgccgc ggccgacgag gtgtacgaca cctacgtcgg cgtgggccgc
    13921 aacgaggcgc tgaagaagta cgcggccctg accggcgtcg agcggttctc ccgtccgccc
    13981 ggcggcgggc ggcacgaggt caccgacctc gactccttca ccccgccgga cgacgtccgg
    14041 gccatcctcg accgcttctt cctgcacatc ttccgcccca ccgcccgcta tgccccggac
    14101 atcgcggcgc tgcgggccgc ctccgcgcct gtcgtggtgg gcggcggcac cacgtccaag
    14161 gggcagctgt cccaccgggc cgcggtcgca ctggccggtc agctcggcac gcacgtcgtc
    14221 gacttccccg gtgaccacac cggcttccag ggcgaacccg aggcgttcgc cgccaccctg
    14281 cgccgagtgc tcaccggaac ggcatgaacg acgcccaggg aaccgcgacg tggagagact
    14341 catgaccgcc ttcagctact ccgactacct gcgcacggac accctgctct ccctgcagcg
    14401 cacccgtacg ccgcccacgg ccgatcgtgc ggtgctgctg gcggaacact tcttcatcgt
    14461 cgcgcaccag tcgtgcgagc tgtggctcaa gcaggtggtc gccgacctgg aggcggtggc
    14521 cggcacgctg tcctcggcga gcggcgccga ggacctggag ctgagcgcgg agtacctgca
    14581 gcgggcgagc gaggtgctgc gggtgctgca cgaccaggtg atcgtgctgg agcggctgcc
    14641 actgcgccac ttcgccgcgt tccggcccta cctcggcacc gcgagcggag cccagtccga
    14701 gcagttcagg acgctcgccc ggctgatcgg cgacgagcgg cggacgggca cgctgtacga
    14761 ggccttcgcg accgcggtga cgcgcctcgg caccaccgtc gccgaggtgt gccggcgcgg
    14821 gaccggtgcg ggagccctcc accgggtcgc cgaggggctg ctcgacatcg gcaacgggta
    14881 ctggcgatgg aaggtggccc atctcggtct cacgtccaag atgctgggcg gccggcccgg
    14941 cacgggtgcc accgacgggg tcgaccacct gctgcgccgg atcacccagc cgttctccga
    15001 actgcgcacg caccgcgagc aggtgcacgc ccccctcgcg cagagcgcgg gttgagaaga
    15061 gggaaaatga tgtcacatgt ggtaatcgtc ggtggcggaa ccgcgggatg gatgaccgcc
    15121 acctacctca aggcggcgtt cggtgagcgg atccaggtga cgctcgtcga atccgagcag
    15181 gtgtcgacga tcggcgtggg cgaggccacg ttcagcaccg tgcggcactt cttccggttc
    15241 ctgggactgg ccgagcacga gtggatgccg gaatgccacg cctcgtacaa gctcgccatc
    15301 cggttcgagg actggcgggc cgagggtcac tacttctacc accccttcga gcgcccgcgg
    15361 acggtgaacg gcttctcgct cgcggagtgg tggcagcacc tgcggcccgg cgaccggttc
    15421 gaccgggacg cctccgtact ggccgcgctg tgcgacgcgc ggagctcacc caagtacctc
    15481 gacggcaccc tgttcgagat ggcgggggag gaccccacac agttcccgta cgcctaccac
    15541 ttcgacgcca cgctgctggc ccgcttcctc cgcgggtacg gcacccggcg cggcgtccgg
    15601 cacgtcgtcg acgacgtcct cgacgtccgc ctcgacgaac gcggccacat ccggaacgtc
    15661 ctcaccaagg aacacggcga gctcgcgggt gacctgttcg tcgactgcac cggcttccgc
    15721 gggatgctgc tgaacaaggc ccttggggtg ccgttcctgt cgtaccagga cagcctgccc
    15781 aacgacagtg cggtcgcgtt gcgggtgccg gtggacgtcg ccaggagggg catgaggccg
    15841 tgtacgacgg ccaccgccca ggccgccggg tggatctgga cgatcccgct gctcgaccgg
    15901 ctcggcaccg ggtacgtgta cgcgagcgac tactgctcac cggaggaggc ggagcggacg
    15961 ctgcgggagt tcgtcggccc ggaggcggac gacgtgacgg cgaaccacat ccggatgagg
    16021 atcgggcgca gcgcccaatc ctgggccggc aactgcgtgg cgatcggcct gtccagcggg
    16081 ttcgtcgagc cgctggagtc gaccgggatc ttcttcatcc agaacggcat cgagcagctg
    16141 gtgcggtact tccctgacgg ccgggacgac gagcggctcc ggcaggcgta caaccggcag
    16201 gtcggccatg tcatggacgg cgtacgggag ttcctcgtgc tgcactacta cgccgcggcc
    16261 cgcgacgaca accagtactg gcgggacgcc aagacgcgcc cgatgcccga cgccctggcc
    16321 gagcgcatcg aacagtggca cacctcgctg cccgacgccg actcggtcta cccgtacttc
    16381 cacggcttcg agccgtactc gtacaccgcc atgctgctgg ggctcggcgg gatccggacc
    16441 cggccgctgc cggtgctcgc ccggctcgac gggaccgatg cggtgaagga gttccaccgg
    16501 atacggcagc aggcggacag cctggtcgac cggctgccga gccagtacga ctacctcgcg
    16561 cagctgcgcg gcggcgcctg agactccggc cccctgcccg ggcgggggcg ccgggcgggc
    16621 ggtacggcct acggctgccg caggacgccg gagaccaccg cgctcaccgt cttgcgtacg
    16681 gccgtgggct ccggcgcggt ggcctgccgg tcggcgaaca gcaggtgccc ggagccgatc
    16741 agcatggggg agagcgtgtc gatgtcggcg tcggcggcga tgcgccccag gtcgcgctcg
    16801 gcgacgaggt acgaggcgat catggccgtg gcctccgtca gcaccgggat gccggtcggc
    16861 gtggtccggc gcagccggcc gcgcagttcg tcccgggaga cgacgaggtt gacgatcccg
    16921 acggtgacgg ggccgaacag gtccgtcagc gcaccggcga ggttgtccac gacggtgccg
    16981 ctcccggcgc ggtcgcgcag ggcggcggcc tggtcgtcga tccggcccat gcggtcccgt
    17041 acgagctcgg cgaggaaggt gtcgaagtcg gcgaagtgcc ggtgcagtac gcccttggcg
    17101 cagcccgcct ccgtggtgac ctcccggctg gtcagcgcgt tcggcccgcc ccggagcaga
    17161 acgcgctcgg cggcaccgaa cagctgccgg cgtacgtcgc ggatggctac ccctgtcggc
    17221 atcgtgcggc cctccttcgc ttgctgggac cagtcgttga ccagtgggca cctgcccact
    17281 agggtgggcg catgcccact atacccccag tcgtgtccac aggaggttcc cgggaagcag
    17341 tgccggccac ggcggccggc cgcgagttgt acggggttgc ggacccggtc cgcgagctgt
    17401 ggcgccaggc accggtacgg gagatcacca cggagaccgg catgaagggc tggctggtca
    17461 ccggtatgga ggaggtacgg gtcgccctgt ccgacccccg gttcagccgg gccgaggccc
    17521 ggcggatcgg cgcggtggtc atgccctcgg cggtcttcga gaagccgggg atcaacgacc
    17581 tcgacggagc cgagcacacc cggctgcgcc gcctcgtggc gggggcgttc agcgcacgcc
    17641 gcatccgcgc cctccggccc cgcgtccagc gcatcaccga tgagctgatc accgccctgg
    17701 ccgccgccgg tccgcccgcc gacctcgtcg ccgggctgtg ccgcccgctc ccgctcaccg
    17761 tgatcttcga gatcctcggc gtcccgcagc aggacagggc gcgcttcagc ggctgggccg
    17821 accgcgtcat ggccgccggc gcctactcgc cggaggagtc cctgaaggcg ctccacgcgg
    17881 tggtggacta catgaccgag ctcgtcgacg ccaagcgtcg cgcccccgac gacagcctgc
    17941 tccaggacct gatcgcggcc cgcgacgagc acgaccggct gagcgagcag gagttggtcc
    18001 acctcggctg cggtctgctc atggccggca acgaatccac cgcgaccatg ctcggcaagg
    18061 gactgctggc cctgctggac aacccggacc agctcgcggc gctgcgcgcc gacccgtcgc
    18121 tcctgccgtc cgccgtggag gaggtgctgc ggtacgcgcc gctggccgcc cgcccgtacg
    18181 gcggtcaggt acgggccacc acgtgcgacg tcgagctggg cggtgtgacc atccccgcgc
    18241 acagcgtggt cttcgccgcc gtgccggccg ccaacctcga tccggggacg ttccccgatc
    18301 ccgtccgctt cgacatcacc cgtgagggcg ccgccgaaca cgtcacgttc ggctacggcc
    18361 cgcaccgctg cctgggcgcc caactcgccc gtatggagct ggaggtggcg ttcggcagcc
    18421 tgctcgccgc cttcccccga ctgcggccgg cggtgcccgt cgaagaactc tcccacgccg
    18481 agggcaggct catgaccggg cttctggagc tgcccgtcac ctggtgagtg ccggccgggc
    18541 gtacctggca caccgttcag gcctacgaga aagagatgac ttgtgaacga gcacgcagtc
    18601 gaaggcggtg cccgggcggc agccgaggac gcgccgccgg agagggaggt ggccggcttc
    18661 tacaacgaca tcagcggcct cctcaccgag ctgttcggcg ggagcctgca cgaggggtac
    18721 tgggaatccc cctccgaccg ctccacgatg gccgaggcgt cgcagcggct caccgacctg
    18781 ctgacggaga agctgaaggc cgggccgggg gacacggtcc tcgacgtcgg gtgcggatcg
    18841 ggcgctccgg cgatccggct cgcgcgggtg acgggcgcgc gggtggtcgg gatcaccaac
    18901 agtgacgtac agatccaggc ggccgtacgc aacgcccagg acgccggtat gggcgagcag
    18961 gtgacgttcc ggtgcgagga cgccacggtc ctggacttcc cggcggggtc gttcgacggg
    19021 gtgctgatga tcgagtcgat cttccacctc ccggaccggc tcggcgcgct gcgggaggcg
    19081 gcgaaggtgc tcaagccggg cggacggctg gccctgacgg acctgctgga cctgacgccg
    19141 gtgcggcacg gcatggcgga ggccatgggc gacctggccg agcacgggca tgagcacggg
    19201 cacgcgcccc tggtggccag gccgataccg ctgcggcggt acgagacgct cctcgaagag
    19261 gccggcctgg ttcccgtcga gctgacggac gtcaccgaac acacggtggc ccccacgctc
    19321 gcctgcatcc gcaagaagct cgacgaggac cacgaccggc tcgtcgagac gttcggcagc
    19381 caggtcgtga agcagtacga gacggttctg ccgcttctgg agtcggccgg tttcgggtac
    19441 gccgtcgtcg tcgcggaggt tcctggaggg tgaaccgatg agccggccgc ctcgtggccg
    19501 tgcggtggag ccgggaccgg tgcggtcccg gctccgcttc gtttcccgcc gtttgacgag
    19561 tgggcatgcg cccattaaag tgggcgcatg cccactcttc ccgagaacca gcctcaccgg
    19621 cagcgccagg tcgcggagtc gttcggcacg gacgccgagc gctacgaccg ggcgcggccc
    19681 cgctaccccg aagccctggt ggagcggatc gtcgccgaca gccccggcgt cacggtcctc
    19741 gacgtcggct ccggcaccgg catcgccgca cggcagttcc aggcccacga ctgcacggtc
    19801 ctcgcggtcg agcccgacga acggctggcc gagctggcca ggcagctcgg cgtcgagacc
    19861 gacgtggcca cgttcgaagc ctgggagccg gccgggcggg agttcgacgc cgtcgtcgcc
    19921 gcccaggcgt ggcactgggt cgacccggtg gcgggcgcgg ccaaggccgc gcgggtgctg
    19981 cgccccgccg gccggctggc ggtgttctgg aacgtcttcc agttcccgcc ggacgtggcg
    20041 gacgtcgtcg ccgaggtctg cgagcgggtg atgcccaacg cgccgttcag cttcacggcg
    20101 atgacgaagg gggccatgga cgggtaccag gagttcttcg ccaagtccgc cgacggcatc
    20161 cgcaccgcgg gcgggttcgg cgagccggag cagtggcggt acgactggga gtggacgtac
    20221 accaaggacg cctggctgga ccagatgccc acgctcggcg ccttcacccg gctcccggag
    20281 gacaagatgg ccgaggtgct gcggggcgtc ggggacgcca tcgacgccat gggcggcagc
    20341 ttcaccatgg ggtatgccac ggtggccgtt accgcgcggc gcaccgacgc cccctgatcc
    20401 cgctcgtccg cgacatccgg tgcgccggcg tccccggcgc gaggagagga acatcatgcg
    20461 agttctggtg ctgggcggta cccattacgt gggacgcgcc ctcgtcgagg cggcgttggc
    20521 gcgcggtgat gacgtcagca ccctcaaccg cggcctcagc gcacccgccg cgaaaggcgt
    20581 cgagaccctg atcgccgacc ggaccgatcc ccgggcgctg cgccgggcga tcggcgacca
    20641 gaagtgggac gccgtcgtcg acacctggaa cggggcgccg cgtgtcatcg ccgacagcag
    20701 cgcgctcctg gccgaccggg tccggcactt cggatacgtc tccagctggg tggtgtaccg
    20761 gccaccggta ccgcacggcg ccgacgagtc cgccgccgtg atcgacggcg acccggacga
    20821 cagcgccgac gggttctacc ccacggccaa gcgcggcgcc gagctcggcg tgctccgcgc
    20881 cttcggggac cgcgccctga tcgcccgccc cgggccgatg ctgggcccgt acgaggacgt
    20941 cggctcgctg acctggtggc tgcgccgcat cgagcgcggc ggacgggtcc tggcccccgg
    21001 tgcgccggac gaccccttgc agtacgtcga cgtccgggac cacgcggtgt ggatgctgga
    21061 cgccgcggaa cggggcatcg gcggcacgtt caacaccgtg tgcccccgcg ggcgtcacac
    21121 catgggggag ctgctggaga cgatgtgccg ggtgaccggg tccgacgcgg aactggtctg
    21181 ggccggcgac gacatcctca tggcggaggg cgtccgcccg tacctcgaca tcccgctgtg
    21241 gctcccggcg gccatgcggg gcggcatcca tgacgtcgac gtcaccgccg cccacgacgc
    21301 cggactcgac accggccgcc cgctggagga caccctcgcc gacacctggt cctggctgcg
    21361 gcgcgagggc gagccgccct ggcagcagac cgacacgcgc cgcggactgg accccgccac
    21421 cgaacagcgc gtactggaca aggtcggctg accgcatgcg acagcagacg gacgaagccg
    21481 ggttctacaa cgacacgagc gagttcctcg ccgaactgtc cggcggcagc ctgcacatgg
    21541 gctactggga atccccgtcg gaccggtcga cgatggcgga ggcgtcccag cggctcaccg
    21601 acctgatgac ggagaagacg aaggccgggc cggcggacag ggtgctcgac atcggttgcg
    21661 ggaccggcgc tcccgcgatc cggctcgcgc ggaccacggg cgcacaggtc gtcgggatca
    21721 ccgacagccc cgtacaggcg cgactggccg tacggagcgc ggaggacgcc ggaatcggcg
    21781 accgggtgac gttccggcgc gaggacgcca tggatcttcc cttcccggcg cagtcgttcg
    21841 acgtggtgtg gctcctggag tcgctgatgg ccatgccgga ccggctcgga gcgctgcggc
    21901 aggcggcgcg cgtgctcgta ccgggcggcc ggctggccct caccgacttc ctggaccgcg
    21961 ctccggcgcc ggccaccggg cggagaacgc cgggtgagca cgaggggtcg acgctgatga
    22021 ccaagctgat accgctggcc gactacgact cactcctcga acaggcgggc ctggtccccg
    22081 tcgagacgac cgacatcacc gaccacacgg tggagcgcac cctcacctgc atgcggcaga
    22141 agctgacgga ggaccgcgag gacctggtcc ggaggttcgg ggccccggtc gtcgaccagt
    22201 tcgacgccat cgtcgcgcgc ctgcgggcgg tcggcctcgg atacggcctc gtcgtcgcga
    22261 cccgccccgt gcggtgacca caccgcgggg ccggccccgg ccgtccggcc ggcaccggcc
    22321 ccgcggccgc gaccaggacg ctacggacgt acgaaggcga cttcggggaa cgccgcgcac
    22381 ggcccgtcga gcaacgggcg cggtacgccc cgcagatggc ggtcgacgaa ggcgccgaca
    22441 taggcccggg tgatcaccgt ggcccggtca ccggagaggg tgccgaacag ctgcggctcc
    22501 agctcgggtg gaatcacccc gctcaggtcg aagtgctcgt acagccagtg ggcgtcgctg
    22561 aaggacaggt gacccgcggt gggcacactg agccaccgct tccaaccggc caggccaccc
    22621 cagcggtcca cccaattggc ggcgggagtc ccaccggccg tgggccactg ggcacccagc
    22681 aacagcaccg gccgggacac cggctcctgg ggccgctccg tgaagaacgt gccctccatg
    22741 ttgacggcgg cgtcgacgcg aggatcctcg ctcagggtct cgacagcact cgctccgcct
    22801 atggagtgac ccaccacggc gatccgggaa ccgtcgacgg gaagccccga acccggcccg
    22861 gtcagctggt ccaggaggaa gtggatgtcc ttgacccggc tgcgcaccac atcggcgttg
    22921 ccctggcccg tacacatcga acagggctcc aggcgcccgc cggggaactc cacgaacgcc
    22981 tcgtaggtgt ggtccagcgc ggccacgaca tacccccggg aggcgagctc ctcgcccagc
    23041 gacgtcagcg acacgcgcgt cataccgtaa ccgggggaca gcaccacgag cggccgcgcc
    23101 ccgggcagcg cggccgcgtc cacggtcgag tgcgtacgca cggtgctgag ggcatcggtg
    23161 ccgaaggcgg cggaggacag ctgcgcggac atgaacggcg ccgcacggcc ggagggccgc
    23221 acggccggat accacacggt ggccatcagc tcccggaagt ccttgccggg cttccacggg
    23281 tcgggccgtg acgtgtcctt caggtgcagg gatctgctgc cgatccgaag tgcgcccgtc
    23341 ggcgcgggca gttcgggtcc cgaggtggtc cgtacggagg attcggcgga ggccgcggcc
    23401 gcgctcggaa ctccggggac cacgagggcc cccaggagag cgagcgagac ggcggcgagt
    23461 cgtaagaatc gtggggacat ggccccacgc tacgggaccc gtgatcgccg ggtcacggat
    23521 cccgcccacg ccgtacgccc ctactcgacc gcctcgtacg agacgaccgg ccgcgacgcc
    23581 gagaccagtt ggtctccgtc gtagacggcc tcgacggccg gggggcggct caggaagcgc
    23641 gtcaggctcg cggtcggccc gtaggcgccg acgttgggta cgcacagcag gtcgccctcg
    23701 cgcggtcgcg gcagggtggt cctgaccgcg aggcggtcca ggggcgtgca caggggcccc
    23761 accacgtcgg ccgtgacggg ctcgcggtcg tcgccggcgg agaggttgac gaaaccggtg
    23821 gcggggcgga ggaccctgcc gaggccgctc attccgccga ggacgttgat cccggcgtcc
    23881 agcacgacga tcgtgccctc cgggcgctcc ttgacgtcca gcaccctggt gagcagatgg
    23941 ccggccgagg cgaccaggcg ccggccggac tcgaagtaca cctggggcgc cggccccgtc
    24001 gcccacgtgg acagcagctt gtccagctcc tcccgcagcc cggtcagcac cgcgcccgcg
    24061 ccgggtgtgg cgtacggcca ggggaagccg ccgcccaggt cgacgacgcc gagcgggatc
    24121 cccgcctccc gggcgaccag ttccatggtg ctcctggccg tggcgaaacc gtcccgcaag
    24181 gcctcgacgt cggggaactg cgacccgagg tacacgtggc agccgcggac ctcgaccccg
    24241 ctcggcacct cggcgcaggc ccgtacggcg tcctcgggcg taaacccgaa ctggcggccg
    24301 tcgcccatgg acaggcccgc cttggaaccg gtcggcggct gcagccgcag cagtgcccca
    24361 gcccgcgtcc cggtcgcggc ggtcgcccgg ccgagacggc gcagttcggc ggccgactcg
    24421 caggagaacg acgtcacccc ccgcgccagc gcctcctcga tctcggcggc cgacttgccg
    24481 gggccggtgt agaggatctc ctccgcggcg tgccccgcct ccagggccac ggccagctcc
    24541 ccgggcgagg agacctcggc ccggcacccg gcccggcgga gttcggccac gaccgagggg
    24601 tgggggttcg ccttcagcga gtagagcagg ctcgccgcct cgggcaggac cgaccacagc
    24661 tccgcggccc ggcgccgcag ttccgcgagg tcgtagacgt agagcggggt gccgaaccgg
    24721 tcggcggcct cccggagagt gcgttcggtc at
//
